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Works (9)
Updated: April 5th, 2024 12:44
2023 article
Application of Ion Mobility Spectrometry-Mass Spectrometry for Compositional Characterization and Fingerprinting of a Library of Diverse Crude Oil Samples
Cordova, A. C., Dodds, J. N., Tsai, H.-H. D., Lloyd, D. T., Roman-Hubers, A. T., Wright, F. A., … Rusyn, I. (2023, August 22). ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY.
author keywords: Analytical chemistry; Environmental chemistry; Hazard; risk assessment; Mixtures; Oil spills
TL;DR:
It is found that IMS-MS data has complementary advantages for fingerprinting and characterization of diverse crude oils and that the proposed polycyclic aromatic hydrocarbon (PAH) biomarkers can be used for rapid exposure characterization.
(via Semantic Scholar)
doi.org (publisher)
Source: Web Of Science
Added: September 5, 2023
2022 journal article
Clomifene and Assisted Reproductive Technology in Humans Are Associated with Sex-Specific Offspring Epigenetic Alterations in Imprinted Control Regions
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(18).
author keywords: differentially methylated regions; adverse offspring outcomes; infertility
MeSH headings : Child; Clomiphene; DNA Methylation; Female; Genomic Imprinting; Humans; Male; Reproductive Techniques, Assisted / adverse effects; Retrospective Studies
TL;DR:
The results suggest that the increased risk of adverse outcomes in offspring conceived through ART may be due in part to altered methylation of ICRs, and larger studies utilizing epigenome-wide interrogation are warranted.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 3, 2022
2022 article
Sex-specific DNA methylation and associations with in utero tobacco smoke exposure at nuclear-encoded mitochondrial genes
King, D. E., Sparling, A. C., Lloyd, D., Satusky, M. J., Martinez, M., Grenier, C., … Murphy, S. K. (2022, March 5). EPIGENETICS.
author keywords: Sex differences; mitochondria; DNA methylation; in utero smoke exposure
MeSH headings : Female; Humans; Male; Adenosine Triphosphate; DNA Methylation; Genes, Mitochondrial; Hormones; Reactive Oxygen Species; Tobacco Smoke Pollution; Sex Factors; Maternal Exposure
TL;DR:
The findings suggest that sex-specific DNA methylation may help establish sex differences in expression and function and thatsex-specific alterations inDNA methylation in response to exposures could contribute to sex-variable toxicological responses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: March 21, 2022
2021 journal article
Associations between maternal obesity, gestational cytokine levels and child obesity in the NEST cohort
PEDIATRIC OBESITY, 16(7).
Contributors: R. Maguire n, J. House n , n, H. Skinner n, T. Allen *, A. Raffi n, D. Skaar n, S. Park n
author keywords: cytokines; maternal obesity; childhood obesity
MeSH headings : Black or African American; Body Mass Index; Child; Child, Preschool; Cohort Studies; Cytokines / blood; Female; Humans; Obesity, Maternal / epidemiology; Pediatric Obesity / epidemiology; Pregnancy; White People
TL;DR:
Although maternal systemic inflammation is hypothesized to link maternal pre‐pregnancy obesity to offspring metabolic dysfunction, patient empirical data are limited.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
5. Gender Equality
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 19, 2021
2021 journal article
Data Processing Workflow to Identify Structurally Related Compounds in Petroleum Substances Using Ion Mobility Spectrometry-Mass Spectrometry
ENERGY & FUELS, 35(13), 10529–10539.
TL;DR:
This work demonstrates how rapid untargeted IMS-MS analysis and the proposed data processing workflow can be used to provide confident compositional characterization of hydrocarbon-containing substances.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: July 26, 2021
2021 journal article
Environmental impacts of Hurricane Florence flooding in eastern North Carolina: temporal analysis of contaminant distribution and potential human health risks
JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, 31(5), 810–822.
author keywords: Disaster research response; Superfund; Chemical contaminants
MeSH headings : Cyclonic Storms; Environmental Monitoring; Gas Chromatography-Mass Spectrometry; Humans; Metals; North Carolina / epidemiology; Soil
TL;DR:
PAH and metals detected downstream from the coal ash storage pond that leaked were detected and were indicative of a pyrogenic source of contamination and PAH at these sites were of human health concern because cancer risk values exceeded 1 × 10−6 threshold.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: May 24, 2021
2021 journal article
Risk Characterization of Environmental Samples Using In Vitro Bioactivity and Polycyclic Aromatic Hydrocarbon Concentrations Data
TOXICOLOGICAL SCIENCES, 179(1), 108–120.
author keywords: polycyclic aromatic hydrocarbons; mixtures toxicology; in vitro models; iPSC; humanized models; human risk assessment; risk assessment; new approach methods; bioactivity; spatial analysis
MeSH headings : Cyclonic Storms; Endothelial Cells; Environmental Exposure / adverse effects; Environmental Monitoring; Humans; Polycyclic Aromatic Hydrocarbons / toxicity
TL;DR:
This work sets the stage for identification of the areas of concern and direct quantitative risk characterization based on bioactivity data, thereby providing an important supplement to traditional individual chemical analyses by shedding light on constituents that may be missed from targeted chemical monitoring.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: March 15, 2021
2020 journal article
Classification of estrogenic compounds by coupling high content analysis and machine learning algorithms
PLOS COMPUTATIONAL BIOLOGY, 16(9).
MeSH headings : Algorithms; Cell Line; Estrogens / classification; Estrogens / metabolism; Humans; Machine Learning; Receptors, Estrogen / metabolism
TL;DR:
A machine learning pipeline for rapid, accurate, and sensitive assessment of the endocrine-disrupting potential of benchmark chemicals based on data generated from high content analysis showed that highly accurate and generalized classification models with a minimum number of features can be constructed without loss of generality.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: October 26, 2020
2020 journal article
Low-Dose Silver Nanoparticle Surface Chemistry and Temporal Effects on Gene Expression in Human Liver Cells
SMALL, 16(21).
Contributors: J. House n , E. Bouzos*, K. Fahy *, V. Francisco*, n, F. Wright n, A. Motsinger-Reif*, P. Asuri *, K. Wheeler*
author keywords: nanotoxicity; silver nanoparticles; transcriptomics
MeSH headings : Gene Expression / drug effects; Hepatocytes / drug effects; Humans; Metal Nanoparticles / chemistry; Silver; Surface Properties; Time Factors
TL;DR:
Universal to all surface coatings, AgNP-treated cells responded by inactivating proliferation and enabling cell cycle checkpoints, which provide a foundation for understanding hepatic response to low-dose AgNPs for future risk assessment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 14, 2020
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