Works (5)

Updated: July 5th, 2023 15:29

2021 journal article

Population genomics of invasive rodents on islands: Genetic consequences of colonization and prospects for localized synthetic gene drive

EVOLUTIONARY APPLICATIONS, 14(5), 1421–1435.

By: K. Oh*, A. Shiels*, L. Shiels*, D. Blondel n, K. Campbell*, J. Saah n, A. Lloyd n, P. Thomas* ...

author keywords: Cas9; CRISPR; genetic biocontrol; genome editing; Mus musculus; synthetic biology
TL;DR: Results from pooled whole‐genome sequencing of invasive mouse populations on four islands along with paired putative source populations are used to test genetic predictions of island colonization and characterize locally fixed Cas9 genomic targets. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 29, 2021

2019 journal article

Controlling invasive rodents via synthetic gene drive and the role of polyandry

Proceedings of the Royal Society B: Biological Sciences, 286(1909), 20190852.

author keywords: gene drive; polyandry; invasive species; pest control; house mouse
MeSH headings : Animals; Ecosystem; Female; Gene Drive Technology; Genes, Synthetic; Introduced Species; Islands; Male; Mice / physiology; Pest Control / methods; Rodentia / physiology; Sexual Behavior, Animal; Spermatozoa
TL;DR: It is found that polyandry substantially hampers the spread of t-Sry such that release efforts have to be increased three- to sixfold for successful eradication. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: September 9, 2019

2019 journal article

Development of an Online Experiment Platform for High School Biology

JOURNAL OF FORMATIVE DESIGN IN LEARNING, 3(1), 62–81.

By: D. Blondel*, A. Sansone*, J. Rosenberg*, E. Godin*, B. Yang*, L. Jaglom-Kurtz*, L. Linnenbrink-Garcia*, R. Schwartz-Bloom*

author keywords: Online lab experiments; High school biology; Virtual experiments; Neuroscience; Drugs; Situational interest
TL;DR: A novel online platform that immerses students in a scientific investigative process, Rex (Real experiments), that uses zebrafish and rats as model systems to study the effects of drugs such as tetrahydrocannabinol, caffeine, alcohol, and cigarette smoke is developed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Source: Web Of Science
Added: July 8, 2019

2019 journal article

Locally Fixed Alleles: A method to localize gene drive to island populations

SCIENTIFIC REPORTS, 9.

By: J. Sudweeks n, B. Hollingsworth n, D. Blondel n, K. Campbell, S. Dhole n, J. Eisemann*, O. Edwards*, J. Godwin n ...

MeSH headings : Alleles; Animals; Biodiversity; Islands
TL;DR: This paper proposes the “Locally Fixed Alleles” approach as a novel means for localizing elimination by a drive to an island population that exhibits significant genetic isolation from neighboring populations and explores the feasibility and degree of localization that can be achieved. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: November 18, 2019

2019 journal article

Sustainability as a Framework for Considering Gene Drive Mice for Invasive Rodent Eradication

Sustainability, 11(5), 1334.

By: S. Barnhill-Dilling n, M. Serr n, D. Blondel n & J. Godwin n

author keywords: gene drives; invasive species management; sustainability
Sources: Web Of Science, NC State University Libraries, Crossref
Added: April 15, 2019

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