Works (47)

2019 journal article

Locally Fixed Alleles: A method to localize gene drive to island populations

SCIENTIFIC REPORTS, 9.

By: J. Sudweeks, B. Hollingsworth, D. Blondel, K. Campbell, S. Dhole, J. Eisemann, O. Edwards, J. Godwin ...

Source: Web Of Science
Added: November 18, 2019

2019 journal article

Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse

CHEMICAL RESEARCH IN TOXICOLOGY, 32(5), 887–898.

By: L. Lewis, B. Borowa-Mazgaj, A. Conti, G. Chappell, Y. Luo, W. Bodnar, K. Konganti, F. Wright ...

Source: Web Of Science
Added: June 17, 2019

2019 journal article

Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Population-Based Analysis of Toxicokinetics and Kidney Toxicodynamics of Tetrachloroethylene

ENVIRONMENTAL HEALTH PERSPECTIVES, 127(6).

By: Y. Luo, J. Cichocki, N. Hsieh, L. Lewis, F. Wright, D. Threadgill, W. Chiu, I. Rusyn

Source: Web Of Science
Added: July 29, 2019

2018 journal article

Permissiveness to form pluripotent stem cells may be an evolutionarily derived characteristic in Mus muscuius

SCIENTIFIC REPORTS, 8.

By: T. Garbutt, T. Konneker, K. Konganti, A. Hillhouse, F. Swift-Haire, A. Jones, D. Phelps, D. Aylor, D. Threadgill

Source: NC State University Libraries
Added: October 16, 2018

2015 journal article

Sensitivity to hepatotoxicity due to epigallocatechin gallate is affected by genetic background in diversity outbred mice

Food and Chemical Toxicology, 76, 19–26.

By: R. Church, D. Gatti, T. Urban, N. Long, X. Yang, Q. Shi, J. Eaddy, M. Mosedale ...

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Epidermal growth factor receptor plays a role in the regulation of liver and plasma lipid levels in adult male mice

American Journal of Physiology. Gastrointestinal and Liver Physiology, 306(5), G370–381.

By: L. Scheving, X. Zhang, O. Garcia, R. Wang, M. Stevenson, D. Threadgill, W. Russell

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Identification and characterization of an invasion antigen B gene from the oral pathogen Campylobacter rectus

Indian Journal of Microbiology, 54(1), 33–40.

By: M. LaGier & D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018

2014 article

Status and access to the Collaborative Cross population (vol 23, pg 706, 2012)

Mammalian Genome, Vol. 25, pp. 192–192.

By: C. Welsh, D. Miller, K. Manly, J. Wang, L. McMillan, G. Morahan, R. Mott, F. Iraqi, D. Threadgill, F. Villena

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Using the emerging Collaborative Cross to probe the immune system

Genes and Immunity, 15(1), 38–46.

By: J. Phillippi, Y. Xie, D. Miller, T. Bell, Z. Zhang, A. Lenarcic, D. Aylor, S. Krovi ...

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Conditional inactivation of TNF alpha-converting enzyme in chondrocytes results in an elongated growth plate and shorter long bones

PLoS One, 8(1).

By: K. Saito, K. Horiuchi, T. Kimura, S. Mizuno, M. Yoda, H. Morioka, H. Akiyama, D. Threadgill ...

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Identification of a novel polymorphism in X-linked sterol-4-Alpha-Carboxylate 3-Dehydrogenase (Nsdhl) associated with reduced high-density lipoprotein cholesterol levels in I/LnJ mice

G3-Genes Genomes Genetics, 3(10), 1819–1825.

By: D. Bautz, K. Broman & D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Modeling host genetic regulation of influenza pathogenesis in the collaborative cross

PLoS Pathogens, 9(2).

By: M. Ferris, D. Aylor, D. Bottomly, A. Whitmore, L. Aicher, T. Bell, B. Bradel-Tretheway, J. Bryan ...

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Pleiotropic effects of the trichloroethylene-associated P81S VHL mutation on metabolism, apoptosis, and ATM-mediated DNA damage response

JNCI-Journal of the National Cancer Institute, 105(18), 1355–1364.

By: M. DeSimone, W. Rathmell & D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Tumor fibroblast-derived epiregulin promotes growth of colitis-associated neoplasms through ERK

Journal of Clinical Investigation, 123(4), 1428–1443.

By: C. Neufert, C. Becker, O. Tureci, M. Waldner, I. Backert, K. Floh, I. Atreya, M. Leppkes ...

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Both stromal cell and colonocyte epidermal growth factor receptors control HCT116 colon cancer cell growth in tumor xenografts

Carcinogenesis, 33(10), 1930–1939.

By: R. Mustafi, U. Dougherty, H. Shah, H. Dehghan, A. Gliksberg, J. Wu, H. Zhu, L. Joseph ...

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Dietary calcium supplementation enhances efficacy but also toxicity of EGFR inhibitor therapy for colon cancer

Cancer Biology & Therapy, 13(3), 130–137.

By: E. Rinella, E. Bankaitis & D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

EGF receptor is required for KRAS-induced pancreatic tumorigenesis

Cancer Cell, 22(3), 304–317.

By: C. Ardito, B. Gruner, K. Takeuchi, C. Lubeseder-Martellato, N. Teichmann, P. Mazur, K. DelGiorno, E. Carpenter ...

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Efficacy of EGFR inhibition is modulated by model, sex, genetic background and diet: Implications for preclinical cancer prevention and therapy trials

PLoS One, 7(6).

By: E. Rinella & D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation

Journal of Experimental Medicine, 209(6), 1105–1119.

By: C. Franzke, C. Cobzaru, A. Triantafyllopoulou, S. Loffek, K. Horiuchi, D. Threadgill, T. Kurz, N. Rooijen, L. Bruckner-Tuderman, C. Blobel

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Expression quantitative trait loci for extreme host response to influenza a in pre-collaborative cross mice

G3-Genes Genomes Genetics, 2(2), 213–221.

By: D. Bottomly, M. Ferris, L. Aicher, E. Rosenzweig, A. Whitmore, D. Aylor, B. Haagmans, L. Gralinski ...

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Genetic analysis of hematological parameters in incipient lines of the collaborative cross

G3-Genes Genomes Genetics, 2(2), 157–165.

By: S. Kelada, D. Aylor, B. Peck, J. Ryan, U. Tavarez, R. Buus, D. Miller, E. Chesler ...

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Genome-wide association mapping of loci for antipsychotic-induced extrapyramidal symptoms in mice

Mammalian Genome, 23(5-6), 322–335.

By: J. Crowley, Y. Kim, J. Szatkiewicz, A. Pratt, C. Quackenbush, D. Adkins, E. Oord, M. Bogue ...

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Mapping six new susceptibility to colon cancer (Scc) loci using a mouse interspecific backcross

G3-Genes Genomes Genetics, 2(12), 1577–1584.

By: C. Eversley, X. Yuying, R. Pearsall & D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Status and access to the Collaborative Cross population

Mammalian Genome, 23(9-10), 706–712.

By: C. Welsh, D. Miller, K. Manly, J. Wang, L. McMillan, G. Morahan, R. Mott, F. Iraqi, D. Threadgill, F. Villena

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Ten years of the collaborative cross

G3-Genes Genomes Genetics, 2(2), 153–156.

By: D. Threadgill & G. Churchill

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Architecture of energy balance traits in emerging lines of the Collaborative Cross

American Journal of Physiology. Endocrinology and Metabolism, 300(6), E1124–1134.

By: W. Mathes, D. Aylor, D. Miller, G. Churchill, E. Chesler, F. Villena, D. Threadgill, D. Pomp

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Epidermal growth factor receptor promotes glomerular injury and renal failure in rapidly progressive crescentic glomerulonephritis

Nature Medicine, 17(10), 1242–1272.

By: G. Bollee, M. Flamant, S. Schordan, C. Fligny, E. Rumpel, M. Milon, E. Schordan, N. Sabaa ...

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Epiregulin-dependent amphiregulin expression and ERBB2 signaling are involved in luteinizing hormone-induced paracrine signaling pathways in mouse ovary

Biochemical and Biophysical Research Communications, 405(2), 319–324.

By: K. Kim, H. Lee, D. Threadgill & D. Lee

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Genetic analysis of complex traits in the emerging Collaborative Cross

Genome Research, 21(8), 1213–1222.

By: D. Aylor, W. Valdar, W. Foulds-Mathes, R. Buus, R. Verdugo, R. Baric, M. Ferris, J. Frelinger ...

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice

Toxicological Sciences, 120(1), 206–217.

By: B. Bradford, E. Lock, O. Kosyk, S. Kim, T. Uehara, D. Harbourt, M. DeSimone, D. Threadgill ...

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

MicroRNA expression in the livers of inbred mice

Mutation Research, 714(1-2), 126–133.

By: D. Gatti, L. Lu, R. Williams, W. Sun, F. Wright, D. Threadgill, I. Rusyn

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

The collaborative cross: A recombinant inbred mouse population for the systems genetic era

ILAR Journal, 52(1), 24–31.

By: D. Threadgill, D. Miller, G. Churchill & F. Villena

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Genetic mapping and developmental timing of transmission ratio distortion in a mouse interspecific backcross

BMC Genetics, 11.

By: C. Eversley, T. Clark, Y. Xie, J. Steigerwalt, T. Bell, F. Villena, D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Maternal dioxin exposure combined with a diet high in fat increases mammary cancer incidence in mice

Environmental Health Perspectives, 118(5), 596–601.

By: M. La Merrill, R. Harper, L. Birnbaum, R. Cardiff & D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018

2010 review

Toxicogenetics: population-based testing of drug and chemical safety in mouse models

[Review of ]. Pharmacogenomics, 11(8), 1127–1136.

By: I. Rusyn, D. Gatti, T. Wilshire, S. Kleeberger & D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018

2009 conference paper

Animal models of autism spectrum disorders: Information for neurotoxicologists

NeuroToxicology, 30(5), 811–821.

By: A. Halladay, D. Amaral, M. Aschner, V. Bolivar, A. Bowman, E. DiCicco-Bloom, S. Hyman, F. Keller ...

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Dietary fat alters body composition, mammary development, and cytochrome P450 induction after maternal TCDD exposure in DBA/2J mice with low-responsive aryl hydrocarbon receptors

Environmental Health Perspectives, 117(9), 1414–1419.

By: M. La Merrill, B. Kuruvilla, D. Pomp, L. Birnbaum & D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal

Genes & Development, 23(21), 2521–2536.

By: S. Munger, D. Aylor, H. Syed, P. Magwene, D. Threadgill & B. Capel

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Epidermal growth factor receptor is required for colonic tumor promotion by dietary fat in the azoxymethane/dextran sulfate sodium model: Roles of transforming growth factor-alpha and PTGS2

Clinical Cancer Research, 15(22), 6780–6789.

By: U. Dougherty, D. Cerasi, I. Taylor, M. Kocherginsky, U. Tekin, S. Badal, L. Aluri, A. Sehdev ...

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Mouse population-guided resequencing reveals that variants in CD44 contribute to acetaminophen-induced liver injury in humans

Genome Research, 19(9), 1507–1515.

By: A. Harrill, P. Watkins, S. Su, P. Ross, D. Harbourt, I. Stylianou, G. Boorman, M. Russo ...

Source: NC State University Libraries
Added: August 6, 2018

2009 review

Murine models of colorectal cancer

[Review of ]. Mammalian Genome, 20(5), 261–268.

By: J. Uronis & D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Placental and embryonic growth restriction in mice with reduced function epidermal growth factor receptor alleles

Genetics, 183(1), 207–218.

By: J. Dackor, K. Caron & D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Placental overgrowth and fertility defects in mice with a hypermorphic allele of epidermal growth factor receptor

Mammalian Genome, 20(6), 339–349.

By: J. Dackor, M. Li & D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Population-based discovery of toxicogenomics biomarkers for hepatotoxicity using a laboratory strain diversity panel

Toxicological Sciences, 110(1), 235–243.

By: A. Harrill, P. Ross, D. Gatti, D. Threadgill & I. Rusyn

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Reduced EGFR causes abnormal valvular differentiation leading to calcific aortic stenosis and left ventricular hypertrophy in C57BL/6J but not 129S1/SvImJ mice

American Journal of Physiology. Heart and Circulatory Physiology, 297(1), H65–75.

By: C. Barrick, R. Roberts, M. Rojas, N. Rajamannan, C. Suitt, K. O'Brien, S. Smyth, D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018

2009 review

The gastrointestinal microbiome: a malleable, third genome of mammals

[Review of ]. Mammalian Genome, 20(7), 395–403.

By: I. Carroll, D. Threadgill & D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Tumor-specific apoptosis caused by deletion of the ERBB3 pseudo-kinase in mouse intestinal epithelium

Journal of Clinical Investigation, 119(9), 2702–2713.

By: D. Lee, M. Yu, E. Lee, H. Kim, Y. Yang, K. Kim, C. Pannicia, J. Kurie, D. Threadgill

Source: NC State University Libraries
Added: August 6, 2018