Works (40)

Updated: April 5th, 2024 01:17

2022 journal article

Hands-on childcare garden intervention: A randomized controlled trial to assess effects on fruit and vegetable identification, liking, and consumption among children aged 3-5 years in North Carolina

FRONTIERS IN PSYCHOLOGY, 13.

By: N. Cosco n, N. Wells*, D. Zhang n, L. Goodell n, M. Monsur*, T. Xu*, R. Moore n

author keywords: childcare; gardening; garden intervention; randomized controlled trial; healthy eating; diet; preschool; children
TL;DR: Children who received the garden intervention showed a greater increase in accurate identification of both fruits and vegetables as well as consumption of both fruit and vegetables during the tasting sessions, and the effects on fruit consumption were greater than on vegetable consumption. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: December 19, 2022

2021 journal article

Research Design, Protocol, and Participant Characteristics of COLEAFS: A Cluster Randomized Controlled Trial of a Childcare Garden Intervention

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 18(24).

By: N. Cosco n, N. Wells*, M. Monsur*, L. Goodell n, D. Zhang n, T. Xu*, D. Hales*, R. Moore n

author keywords: children; childcare; gardening; randomized controlled trial; healthy eating; physical activity
MeSH headings : Child; Child Care; Child, Preschool; Fruit; Gardening; Gardens; Health Promotion; Humans; Research Design; Vegetables
TL;DR: By employing an RCT to examine the effect of a garden intervention on diet and physical activity among young children attending childcare centers within low-income communities, this study offers compelling research design and methods, addresses a critical gap in the empirical literature, and is a step toward evidence-based regulations to promote early childhood healthy habits. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 18, 2022

2019 review

Statistical Analysis of Zero-Inflated Nonnegative Continuous Data: A Review

[Review of ]. STATISTICAL SCIENCE, 34(2), 253–279.

By: L. Liu n, Y. Shih*, R. Strawderman*, D. Zhang*, B. Johnson n & H. Chai n

author keywords: Two-part model; Tobit model; health econometrics; semiparametric regression; joint model; cure rate; frailty model; splines
TL;DR: This paper reviews statistical methods for analyzing zero-inflated nonnegative outcome data, discussing ways to separate zero and positive values and introducing flexible models to characterize right skewness and heteroscedasticity in the positive values. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 5, 2019

2016 journal article

A flexible model for correlated medical costs, with application to medical expenditure panel survey data

STATISTICS IN MEDICINE, 35(6), 883–894.

author keywords: model selection; generalized linear model; health econometrics; semiparametric regression; generalized estimating equation
MeSH headings : Aged; Aged, 80 and over; Bias; Computer Simulation; Data Interpretation, Statistical; Health Care Costs / statistics & numerical data; Health Care Costs / trends; Health Expenditures / statistics & numerical data; Health Expenditures / trends; Humans; Linear Models; Male; Models, Economic; United States
TL;DR: A flexible model for correlated medical cost data with several appealing features, including the mean function is partially linear and the covariance structure of correlated medical costs has a semiparametric form is proposed. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Bivariate Mixed Effects Analysis of Clustered Data with Large Cluster Sizes

STATISTICS IN BIOSCIENCES, 8(2), 220–233.

By: D. Zhang n, J. Sun* & K. Pieper*

author keywords: Meta-analysis; Missing data; Multi-center studies
TL;DR: An expected and maximization (EM) algorithm for the REML inference and an ML implementation using existing software and the new REML EM algorithm is easy to implement and computationally stable and efficient. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

A fast EM algorithm for fitting joint models of a binary response and multiple longitudinal covariates subject to detection limits

COMPUTATIONAL STATISTICS & DATA ANALYSIS, 85, 37–53.

By: P. Bernhardt*, D. Zhang n & H. Wang*

author keywords: Detection limit; EM algorithm; Joint model; Logistic regression; Multiple longitudinal covariates; Normal approximation
TL;DR: A fast, approximate EM algorithm is developed that reduces the dimension of integration in the E-step of the algorithm to one, regardless of the number of random effects in the joint model, and is applied to analyze the GenIMS data set. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Assessing gene-environment interactions for common and rare variants with binary traits using gene-trait similarity regression

Genetics, 199(3), 695-.

By: G. Zhao, R. Marceau, D. Zhang & J. Tzeng

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Statistical Methods for Generalized Linear Models with Covariates Subject to Detection Limits

Statistics in Biosciences, 7(1), 68–89.

By: P. Bernhardt*, H. Wang n & D. Zhang n

author keywords: Censored predictor; Complete case; Conditional mean imputation; Detection limit; Improper multiple imputation
TL;DR: It is demonstrated that the conditional mean imputation method often leads to inconsistent estimates in generalized linear models, while several other methods are either computationally intensive or lead to parameter estimates that are biased or more variable compared to the proposed multiple imputation estimator. (via Semantic Scholar)
Source: Crossref
Added: November 21, 2020

2014 journal article

Flexible modeling of survival data with covariates subject to detection limits via multiple imputation

COMPUTATIONAL STATISTICS & DATA ANALYSIS, 69, 81–91.

By: P. Bernhardt n, H. Wang n & D. Zhang n

author keywords: Accelerated failure time model; Censored predictor; Complete case; Detection limit; Multiple imputation; Seminonparametric distribution
TL;DR: A computationally-efficient multiple imputation procedure for modeling survival data with covariates subject to detection limits is proposed in the context of an accelerated failure time model with a flexible seminonparametric error distribution. (via Semantic Scholar)
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Pathway-Guided Identification of Gene-Gene Interactions

ANNALS OF HUMAN GENETICS, 78(6), 478–491.

By: X. Wang n, D. Zhang n & J. Tzeng n

author keywords: Pathway analysis; gene-gene interactions; bio-knowledge-guided
MeSH headings : Computer Simulation; Epistasis, Genetic; Genotype; Humans; Linear Models; Models, Genetic; Polymorphism, Single Nucleotide; Principal Component Analysis; Regression Analysis
TL;DR: A regression model with pathway‐guided regularization for detecting interactions among genes using the principal components to summarize the SNP‐SNP interactions between a gene pair, and an L1 penalty that incorporates adaptive weights based on biological guidance and trait supervision to identify important main and interaction effects is proposed. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

A flexible model for the mean and variance functions, with application to medical cost data

STATISTICS IN MEDICINE, 32(24), 4306–4318.

By: J. Chen*, L. Liu*, D. Zhang n & Y. Shih*

author keywords: generalized linear model; semiparametric regression; health econometrics; smoothing parameter; generalized cross-validation
MeSH headings : Computer Simulation; Delivery of Health Care / economics; Heart Failure / economics; Humans; Likelihood Functions; Models, Economic; Models, Statistical; Virginia
TL;DR: This work considers an extension to generalized linear models by assuming nonlinear associations of covariates in the mean function and allowing the variance to be an unknown but smooth function of the mean. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 chapter

Constructing Conditional Reference Charts for Grip Strength Measured with Error

In Springer Proceedings in Mathematics & Statistics (pp. 299–310).

By: P. Torres*, D. Zhang n & H. Wang n

TL;DR: This work proposes a new semi-nonparametric estimation approach, able to account for measurement errors and allows the subject-specific random effects to follow a flexible distribution, and demonstrates through simulation studies that the proposed method leads to consistent and efficient estimates of the conditional quantiles of the latent response variable. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2012 journal article

A Semi-nonparametric Approach to Joint Modeling of A Primary Binary Outcome and Longitudinal Data Measured at Discrete Informative Times

Statistics in Biosciences, 4(2), 213–234.

By: S. Yan n, D. Zhang n, W. Lu n, J. Grifo* & M. Liu*

author keywords: EM algorithm; Informative observation times; IVF; Joint model; Longitudinal data; Maximum likelihood estimation; SNP density
TL;DR: This work proposes to introduce a third model in the joint model for the informative β-hCG observation times, and relax the normality distributional assumption of random effects using the semi-nonparametric (SNP) approach of Gallant and Nychka (Econometrica 55:363–390, 1987). (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Crossref
Added: August 28, 2020

2012 journal article

Trajectory Analyses in Alcohol Treatment Research

ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 36(8), 1442–1448.

By: J. Chen*, B. Johnson*, X. Wang*, J. O'Quigley*, M. Isaac, D. Zhang n, L. Liu*

author keywords: Alcohol Research; Clinical Trial; Grace Periods; Splines; Mixed Model
MeSH headings : Acamprosate; Adult; Aged; Aged, 80 and over; Alcohol Deterrents / therapeutic use; Alcoholism / drug therapy; Alcoholism / therapy; Algorithms; Behavior Therapy; Combined Modality Therapy; Data Interpretation, Statistical; Double-Blind Method; Female; Fructose / analogs & derivatives; Fructose / therapeutic use; Humans; Linear Models; Male; Middle Aged; Models, Statistical; Naltrexone / therapeutic use; Narcotic Antagonists / therapeutic use; Neuroprotective Agents / therapeutic use; Nonlinear Dynamics; Regression Analysis; Research / statistics & numerical data; Research Design; Taurine / analogs & derivatives; Taurine / therapeutic use; Topiramate; Treatment Outcome; Young Adult
TL;DR: Overall, naltrexone was better than placebo in reducing drinking over time yet was not different from placebo for subjects receiving the combination of a brief medical management and an intensive combined behavioral intervention. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Studying Gene and Gene-Environment Effects of Uncommon and Common Variants on Continuous Traits: A Marker-Set Approach Using Gene-Trait Similarity Regression

AMERICAN JOURNAL OF HUMAN GENETICS, 89(2), 277–288.

MeSH headings : Chromosomes, Human, Pair 21 / genetics; Computer Simulation; Databases, Genetic; Environment; Genes / genetics; Genetic Markers; Humans; Models, Genetic; Mutation / genetics; Quantitative Trait, Heritable; Regression Analysis
TL;DR: A similarity-based regression method for assessing the main genetic and interaction effects of a group of markers on quantitative traits and is an ideal tool for evaluating associations between phenotype and marker sets defined by linkage disequilibrium blocks, genes, or pathways in whole-genome analysis. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Placebo Effect in Canine Epilepsy Trials

JOURNAL OF VETERINARY INTERNAL MEDICINE, 24(1), 166–170.

By: K. Munana n, D. Zhang n & E. Patterson*

Contributors: K. Muñana n, D. Zhang n & E. Patterson*

author keywords: Clinical trials; Dog; Epilepsy; Statistical modeling
MeSH headings : Animals; Anticonvulsants / therapeutic use; Bromides / therapeutic use; Diet / veterinary; Dog Diseases / diet therapy; Dog Diseases / drug therapy; Dogs; Epilepsy / diet therapy; Epilepsy / drug therapy; Epilepsy / veterinary; Linear Models; Phenobarbital / therapeutic use; Placebo Effect; Potassium Compounds / therapeutic use
TL;DR: A positive response to placebo administration, manifesting as a decrease in seizure frequency, can be observed in epileptic dogs, of importance when evaluating open label studies in dogs that aim to assess efficacy of antiepileptic drugs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

The use of pooled vs serial urine samples to measure urine protein:creatinine ratios

VETERINARY CLINICAL PATHOLOGY, 39(1), 53–56.

By: D. LeVine n, D. Zhang n, T. Harris n & S. Vaden n

author keywords: Dog; proteinuria; protein:creatinine ratio; UPC
MeSH headings : Animals; Creatinine / urine; Dog Diseases / diagnosis; Dog Diseases / urine; Dogs; Kidney Failure, Chronic / urine; Kidney Failure, Chronic / veterinary; Proteinuria / veterinary; Specimen Handling
TL;DR: Measuring the UPC ratio in a pooled sample containing equal volumes of several different urine specimens from the same dog provides a reliable and cost-effective alternative to assessing multiple UPC ratios on several specimens fromThe same dog. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Variable Selection for Semiparametric Mixed Models in Longitudinal Studies

BIOMETRICS, 66(1), 79–88.

By: X. Ni*, D. Zhang n & H. Zhang n

author keywords: Correlated data; Gaussian stochastic process; Linear mixed models; Smoothly clipped absolute deviation; Smoothing splines
MeSH headings : Algorithms; Bayes Theorem; Biometry / methods; Computer Simulation; Data Interpretation, Statistical; Epidemiologic Methods; Information Storage and Retrieval / methods; Longitudinal Studies; Models, Statistical
TL;DR: A double-penalized likelihood approach for simultaneous model selection and estimation in semiparametric mixed models for longitudinal data, which provides valid inference for data with missing at random and will be more efficient if the specified model is correct. (via Semantic Scholar)
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Automatic model selection for partially linear models

JOURNAL OF MULTIVARIATE ANALYSIS, 100(9), 2100–2111.

By: X. Ni n, H. Zhang n & D. Zhang n

author keywords: Semiparametric regression; Smoothing splines; Smoothly clipped absolute deviation; Variable selection
TL;DR: A new type of double-penalized least squares is formulated, using the smoothing spline to estimate the nonparametric part and applying a shrinkage penalty on parametric components to achieve model parsimony. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

Gene-Trait Similarity Regression for Multimarker-Based Association Analysis

Biometrics, 65(3), 822–832.

By: J. Tzeng n, D. Zhang n, S. Chang*, D. Thomas* & M. Davidian n

MeSH headings : Chromosome Mapping / methods; Computer Simulation; Genetic Linkage / genetics; Genetic Markers / genetics; Haplotypes / genetics; Humans; Models, Genetic; Models, Statistical; Quantitative Trait Loci / genetics; Regression Analysis
TL;DR: The proposed similarity‐based regression method to detect associations between traits and multimarker genotypes allows for covariates, uses phase‐independent similarity measures to bypass the needs to impute phase information, and is applicable to traits of general types. (via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Power and sample size calculation for log-rank test with a time lag in treatment effect

STATISTICS IN MEDICINE, 28(5), 864–879.

By: D. Zhang n & H. Quan*

author keywords: censoring; intent-to-treat analysis; treatment termination
MeSH headings : Algorithms; Cardiovascular Diseases / drug therapy; Clinical Trials as Topic; Computer Simulation; Epidemiologic Research Design; Humans; Proportional Hazards Models; Sample Size; Statistics, Nonparametric; Time Factors; Treatment Outcome
TL;DR: Simulation studies indicate that the formulas necessary to calculate the asymptotic power of the log‐rank test under this non‐proportional hazards alternative for the two data analysis strategies provide accurate power for a variety of trial settings. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2008 journal article

Anti-Mullerian hormone and inhibin B in the definition of ovarian aging and the menopause transition

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 93(9), 3478–3483.

By: M. Sowers*, A. Eyvazzadeh*, D. McConnell*, M. Yosef*, M. Jannausch*, D. Zhang n, S. Harlow*, J. Randolph*

MeSH headings : Adult; Aging / blood; Aging / physiology; Anti-Mullerian Hormone / blood; Anti-Mullerian Hormone / physiology; Biomarkers / blood; Cohort Studies; Female; Follicle Stimulating Hormone / blood; Forecasting; Humans; Inhibins / blood; Inhibins / physiology; Menopause / blood; Menopause / physiology; Menstruation / blood; Middle Aged; Models, Biological; Ovary / physiology
TL;DR: AMH, an endocrine marker that reflects the transition of resting primordial follicles to growing follicles, declined to a time point 5 yr prior to the FMP; this may represent a critical biological juncture in the menopause transition. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Analysis of a binary composite endpoint with missing data in components

STATISTICS IN MEDICINE, 26(26), 4703–4718.

By: H. Quan*, D. Zhang n, J. Zhang* & L. Devlamynck*

author keywords: EM algorithm; event rate; missing at random; maximum likelihood estimate
MeSH headings : Algorithms; Clinical Trials as Topic; Data Interpretation, Statistical; Endpoint Determination / statistics & numerical data; Humans; Leg; Likelihood Functions; Orthopedics; United States; Venous Thromboembolism / prevention & control
TL;DR: The main idea is to first derive the probabilities of all possible study outcomes based on the appropriate model and then to construct the overall rate for the composite endpoint. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Haplotype-based association analysis via variance-components score test

AMERICAN JOURNAL OF HUMAN GENETICS, 81(5), 927–938.

By: J. Tzeng n & D. Zhang n

MeSH headings : Amyotrophic Lateral Sclerosis / genetics; Computer Simulation; Databases, Genetic; Genetic Predisposition to Disease; Haplotypes; Humans; Likelihood Functions; Models, Genetic; Polymorphism, Single Nucleotide / genetics; Quantitative Trait, Heritable
TL;DR: The broad coverage and the fast and easy implementation of this method make the VC strategy an effective tool for haplotype analysis, even in modern genomewide association studies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Likelihood and pseudo-likelihood methods for semiparametric joint models for a primary endpoint and longitudinal data

Computational Statistics & Data Analysis, 51(12), 5776–5790.

By: E. Li*, D. Zhang n & M. Davidian n

author keywords: conditional score; generalized linear model; mixed effects model; pseudo-likelihood; seminonparametric density
TL;DR: A semiparametric joint model is considered that makes only mild assumptions on this distribution and likelihood-based inference on the association and distribution is developed, which offers improved performance relative to existing methods that is insensitive to the true random effects distribution. (via Semantic Scholar)
Sources: Crossref, Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 journal article

Two-stage functional mixed models for evaluating the effect of longitudinal covariate profiles on a scalar outcome

BIOMETRICS, 63(2), 351–362.

By: D. Zhang n, X. Lin* & M. Sowers*

author keywords: longitudinal covariates; mixed effects models; nonparametric regression; periodic smoothing spline; restricted maximum likelihood; variance components
MeSH headings : Analysis of Variance; Biometry; Bone Density / physiology; Female; Follicle Stimulating Hormone / urine; Humans; Likelihood Functions; Linear Models; Longitudinal Studies; Menopause; Menstrual Cycle; Models, Statistical; Regression Analysis; Statistics, Nonparametric
TL;DR: A measurement error partial functional linear model is proposed, where repeated measures of FSH are modeling using a functional mixed effects model and the effect of the FSH time profile on BMD is modeled using a partialfunctional linear model by treating the unobserved true subject‐specific FSHTime profile as a functional covariate. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2006 journal article

Smoothing spline-based score tests for proportional hazards models

BIOMETRICS, 62(3), 803–812.

By: J. Lin*, D. Zhang n & M. Davidian n

author keywords: Cox model; penalized partial likelihood; smoothing parameter; variance component
MeSH headings : Analysis of Variance; Biometry / methods; Breast Neoplasms / drug therapy; Breast Neoplasms / metabolism; Clinical Trials as Topic / statistics & numerical data; Female; Humans; Likelihood Functions; Menopause; Proportional Hazards Models; Receptors, Estrogen / metabolism
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Sarcopenia is related to physical functioning and leg strength in middle-aged women

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES, 60(4), 486–490.

By: M. Sowers*, M. Crutchfield, K. Richards, M. Wilkin, A. Furniss, M. Jannausch, D. Zhang*, M. Gross

MeSH headings : Adipose Tissue / pathology; Adult; Black or African American; Aging / pathology; Aging / physiology; Body Composition / physiology; Body Mass Index; Electric Impedance; Female; Follow-Up Studies; Gait / physiology; Humans; Isometric Contraction / physiology; Longitudinal Studies; Lower Extremity / physiology; Middle Aged; Motor Activity / physiology; Muscle, Skeletal / pathology; Muscle, Skeletal / physiopathology; Muscular Atrophy / pathology; Muscular Atrophy / physiopathology; Walking / physiology; White People
TL;DR: Even in middle-aged women, there is loss ofLean mass among almost 1 woman in 10, and this loss of lean mass (sarcopenia) is associated with greater compromise in physical functioning. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Conditional estimation for generalized linear models when covariates are subject-specific parameters in a mixed model for longitudinal measurements

Biometrics, 60(1), 07-.

By: E. Li, D. Zhang & M. Davidian

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Construction and evaluation of cDNA libraries for large-scale expressed sequence tag sequencing in wheat (Triticum aestivum L.)

GENETICS, 168(2), 595–608.

By: D. Zhang*, D. Choi*, S. Wanamaker*, R. Fenton*, A. Chin*, M. Malatrasi*, Y. Turuspekov*, H. Walia* ...

MeSH headings : Expressed Sequence Tags / chemistry; Gene Library; Genetic Vectors; Sequence Analysis, DNA; Subtraction Technique; Triticum / genetics
TL;DR: The enrichment methods were effective in reducing the most abundant unigenes and to the observation that the most diverse libraries were from tissues exposed to environmental stresses including heat, drought, salinity, or low temperature. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2004 journal article

Generalized linear mixed models with varying coefficients for longitudinal data

Biometrics, 60(1), 15-.

By: D. Zhang

Source: NC State University Libraries
Added: August 6, 2018

2004 journal article

Likelihood and conditional likelihood inference for generalized additive mixed models for clustered data

JOURNAL OF MULTIVARIATE ANALYSIS, 91(1), 90–106.

By: D. Zhang n & M. Davidian n

author keywords: longitudinal data; marginal likelihood; nonparametric regression; smoothing spline; variance component
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2003 journal article

Hypothesis testing in semiparametric additive mixed models

Biostatistics (Oxford, England), 4(1), 57–74.

By: D. Zhang & X. Lin

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

A Monte Carlo EM algorithm for generalized linear mixed models with flexible random effects distribution

Biostatistics (Oxford, England), 3(3), 347–360.

By: J. Chen, D. Zhang & M. Davidian

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Randomized COMparison of platelet inhibition with abciximab, TiRofiban and eptifibatide during percutaneous coronary intervention in acute coronary syndromes - The COMPARE trial

Circulation (New York, N.Y. : 1950), 106(12), 1470–1476.

Daowen Zhang; Marie Davidian

Source: NC State University Libraries
Added: August 6, 2018

2001 journal article

Linear mixed models with flexible distributions of random effects for longitudinal data

BIOMETRICS, 57(3), 795–802.

By: D. Zhang n & M. Davidian n

author keywords: longitudinal data; multimodality; random effects; seminonparametric density; semiparametric mixed effects model; skewness
MeSH headings : Biometry; Cholesterol / blood; Data Interpretation, Statistical; Humans; Likelihood Functions; Linear Models; Longitudinal Studies
TL;DR: It is demonstrated that standard information criteria may be used to choose the tuning parameter and detect departures from normality, and the approach is illustrated via simulation and using longitudinal data from the Framingham study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2001 journal article

Semiparametric nonlinear mixed-effects models and their applications - Comment

Journal of the American Statistical Association, 96(456), 1288–1291.

By: X. Lin & D. Zhang

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

A scaled linear mixed model for multiple outcomes

Biometrics, 56(2), 593–601.

By: X. Lin*, L. Ryan*, M. Sammel*, D. Zhang n, C. Padungtod* & X. Xu*

MeSH headings : China; Cohort Studies; Computer Simulation; Data Interpretation, Statistical; Humans; Likelihood Functions; Male; Models, Statistical; Occupational Exposure; Pesticides; Semen
TL;DR: A scaled linear mixed model to assess the effects of exposure and other covariates on multiple continuous outcomes and develops two approaches to model fitting, including the maximum likelihood method and the working parameter method. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Semiparametric regression for periodic longitudinal hormone data from multiple menstrual cycles

BIOMETRICS, 56(1), 31–39.

By: D. Zhang n, X. Lin* & M. Sowers*

author keywords: nonparametric regression; penalized likelihood; periodic smoothing spline; restricted maximum likelihood; test for equality of functions
MeSH headings : Biometry; Chi-Square Distribution; Female; Humans; Likelihood Functions; Longitudinal Studies; Menstrual Cycle / blood; Models, Statistical; Progesterone / blood; Regression Analysis; Stochastic Processes
TL;DR: A scaled chi‐squared test for the equality of two nonparametric time functions is developed and it is shown that all model parameters can be easily obtained by fitting a linear mixed model. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

1999 journal article

Inference in generalized additive mixed models by using smoothing splines

Journal of the Royal Statistical Society. Series B, Methodological, 61(1999), 381–400.

By: X. Lin & D. Zhang

Source: NC State University Libraries
Added: August 6, 2018

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