Works (54)

Updated: January 28th, 2024 04:35

2023 journal article

A SARS-CoV-2 and influenza double hit vaccine based on RBD-conjugated inactivated influenza A virus

SCIENCE ADVANCES, 9(25).

By: Z. Wang n, Z. Li n, W. Shi  n, D. Zhu n , S. Hu n , P. Dinh n, K. Cheng n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Cricetinae; Animals; Humans; Mice; Influenza Vaccines; SARS-CoV-2; Influenza, Human; Influenza A Virus, H1N1 Subtype; Pandemics; COVID-19 / prevention & control; COVID-19 Vaccines; Influenza A virus
Sources: ORCID, Web Of Science
Added: June 24, 2023

2023 journal article

An inhaled bioadhesive hydrogel to shield non-human primates from SARS-CoV-2 infection

Nature Materials, 2.

By: X. Mei n, J. Li n, Z. Wang n, D. Zhu n , K. Huang n , S. Hu n , K. Popowski n , K. Cheng

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
Sources: Web Of Science, ORCID, Crossref
Added: March 6, 2023

2023 journal article

Comparison of extruded cell nanovesicles and exosomes in their molecular cargos and regenerative potentials

NANO RESEARCH, 16(5), 7248–7259.

By: X. Wang  n, S. Hu n , D. Zhu n , J. Li n, K. Cheng n & G. Liu *

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: nanovesicles (NVs); exosomes; cardiac repair; mesenchymal stem cells (MSCs); extracellular vesicles (EVs); myocardial infarction (Ml)
Sources: Web Of Science, ORCID
Added: August 28, 2023

2023 journal article

Intrapericardial long non-coding RNA–Tcf21 antisense RNA inducing demethylation administration promotes cardiac repair

European Heart Journal, 44(19), 1748–1760.

By: D. Zhu n , S. Liu n, K. Huang n , J. Li n, X. Mei n, Z. Li n, K. Cheng n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: Myocardial infarction; Adverse remodelling; Mesenchymal stem cell; EVs; lncRNA; Tcf21
MeSH headings : Mice; Animals; Swine; RNA, Long Noncoding / genetics; RNA, Long Noncoding / metabolism; RNA, Antisense / genetics; RNA, Antisense / metabolism; Ventricular Remodeling; Myocardial Infarction / genetics; Myocardial Infarction / therapy; Myocardial Infarction / metabolism; Fibrosis; Demethylation
Sources: Web Of Science, ORCID, Crossref
Added: April 4, 2023

2023 article

Pericardial Delivery of SDF-1 Ξ± Puerarin Hydrogel Promotes Heart Repair and Electrical Coupling

Luo, L., Li, Y., Bao, Z., Zhu, D., Chen, G., Li, W., … Li, Z. (2023, September 15). ADVANCED MATERIALS, Vol. 9.

By: L. Luo *, Y. Li*, Z. Bao *, D. Zhu n , G. Chen*, W. Li*, Y. Xiao *, Z. Wang n ...

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
author keywords: cardiac arrhythmias; electrical coupling; endogenous repair; inflammation regulation; myocardial infarction; SDF-1
Sources: Web Of Science, ORCID
Added: October 23, 2023

2022 journal article

Corrigendum to β€˜A collagen hydrogel loaded with HDAC7-derived peptide promotes the regeneration of infarcted myocardium with functional improvement in a rodent model’ [Acta Biomaterialia 2019, 86, 223-234] (Acta Biomaterialia (2019) 86 (223–234), (S174270611930042X), (10.1016/j.actbio.2019.01.022))

Acta Biomaterialia.

By: Y. Zhang *, D. Zhu* , Y. Wei*, Y. Wu *, W. Cui *, L. Liuqin*, G. Fan *, Q. Yang * ...

co-author countries: China πŸ‡¨πŸ‡³ United Kingdom of Great Britain and Northern Ireland πŸ‡¬πŸ‡§

Contributors: Y. Zhang *, D. Zhu* , Y. Wei*, Y. Wu *, W. Cui *, L. Liuqin*, G. Fan *, Q. Yang * ...

Source: ORCID
Added: April 19, 2023

2022 article

Decoy Exosomes Offer Protection Against Chemotherapy-Induced Toxicity

Fan, M., Li, H., Shen, D., Wang, Z., Liu, H., Zhu, D., … Li, Z. (2022, September 4). ADVANCED SCIENCE, Vol. 9.

By: M. Fan*, H. Li *, D. Shen *, Z. Wang*, H. Liu *, D. Zhu n , Z. Wang n, L. Li* ...

co-author countries: China πŸ‡¨πŸ‡³ United Kingdom of Great Britain and Northern Ireland πŸ‡¬πŸ‡§ United States of America πŸ‡ΊπŸ‡Έ
author keywords: cardio-oncology; cardiotoxicity; chemotherapy; exosome; tetrahedral DNA nanostructure
MeSH headings : Humans; Exosomes / genetics; Exosomes / metabolism; Cardiotoxicity / etiology; Cardiotoxicity / prevention & control; Cardiotoxicity / metabolism; Quality of Life; Neoplasms; Antineoplastic Agents / toxicity; Antineoplastic Agents / metabolism; Chemical and Drug Induced Liver Injury / metabolism
Sources: Web Of Science, ORCID
Added: September 12, 2022

2022 article

Detachable Microneedle Patches Deliver Mesenchymal Stromal Cell Factor-Loaded Nanoparticles for Cardiac Repair

Hu, S., Zhu, D., Li, Z., & Cheng, K. (2022, September 23). ACS NANO, Vol. 9.

By: S. Hu n , D. Zhu n , Z. Li n & K. Cheng n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: mesenchymal stromal cell; secreted factors; microneedle patch; elastin-like peptide gel; hyaluronic acid gel; myocardial infarction; cardiac repair
MeSH headings : Animals; Rats; Elastin; Polylactic Acid-Polyglycolic Acid Copolymer; Hyaluronic Acid; Mesenchymal Stem Cells; Myocytes, Cardiac; Myocardium; Nanoparticles; Peptides
Sources: Web Of Science, ORCID
Added: October 11, 2022

2022 article

Exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain as an inhalable COVID-19 vaccine

Wang, Z., Popowski, K. D., Zhu, D., Abad, B. L. de J., Wang, X., Liu, M., … Cheng, K. (2022, July 4). NATURE BIOMEDICAL ENGINEERING, Vol. 7.

By: Z. Wang n, K. Popowski n , D. Zhu n , B. Abad  n, X. Wang  n, M. Liu n, H. Lutz n, N. De Naeyer* ...

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; Antibodies, Neutralizing; CD8-Positive T-Lymphocytes; COVID-19 / prevention & control; COVID-19 Vaccines; Exosomes; Humans; Mice; Mice, Inbred BALB C; SARS-CoV-2; Viral Vaccines
Sources: Web Of Science, ORCID
Added: July 11, 2022

2022 journal article

Inhalable dry powder mRNA vaccines based on extracellular vesicles

Matter, 5(9), 2960–2974.

By: K. Popowski n , A. Moatti n , G. Scull n, D. Silkstone n, H. Lutz n, B. LΓ³pez de Juan Abad  n, A. George n , E. Belcher  n ...

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
Sources: Web Of Science, ORCID, Crossref
Added: October 17, 2022

2022 journal article

Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3

CIRCULATION RESEARCH, 131(10), E135–E150.

By: D. Zhu n , S. Liu n, K. Huang n , Z. Wang n, S. Hu n , J. Li n, Z. Li n, K. Cheng n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
author keywords: exosomes; immunomodulation; mesesnchymal stem cell; myocardial infarction; regulatory T cell
MeSH headings : Humans; Exosomes / metabolism; Forkhead Box Protein O3 / genetics; Forkhead Box Protein O3 / metabolism; Mesenchymal Stem Cells / metabolism; Myocardial Infarction / pathology; Proto-Oncogene Proteins c-akt / metabolism; Signal Transduction; Heart Injuries / metabolism
Sources: Web Of Science, ORCID
Added: November 14, 2022

2022 journal article

Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem cells in myocardial infarction

CHEMICAL ENGINEERING JOURNAL, 427.

By: J. Li n, Y. Lv *, D. Zhu n , X. Mei n, K. Huang n , X. Wang  n, Z. Li n, S. Zhang n ...

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ

Contributors: J. Li n, Y. Lv *, D. Zhu n , X. Mei n, K. Huang n , X. Wang  n, Z. Li n, S. Zhang n ...

author keywords: Mesenchymal stem cells; Hydrogel; Myocardial infarction; Intrapericardial; Intramyocardial
Sources: Web Of Science, ORCID
Added: January 3, 2022

2022 journal article

Minimally invasive delivery of a hydrogel-based exosome patch to prevent heart failure

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 169, 113–121.

By: G. Cheng n, D. Zhu n , K. Huang n  & T. Caranasos *

co-author countries: United States of America πŸ‡ΊπŸ‡Έ
MeSH headings : Animals; Exosomes; Heart Failure; Hydrogels / therapeutic use; Myocardial Infarction / drug therapy; Myocardium; Rats; Swine
Sources: Web Of Science, ORCID
Added: October 31, 2022

2022 journal article

Nanoparticles functionalized with stem cell secretome and CXCR4-overexpressing endothelial membrane for targeted osteoporosis therapy

JOURNAL OF NANOBIOTECHNOLOGY, 20(1).

By: C. Zhang  n, W. Zhang *, D. Zhu n , Z. Li n, Z. Wang n, J. Li n, X. Mei n, W. Xu *, K. Cheng n, B. Zhong*

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ

Contributors: C. Zhang  n, W. Zhang *, D. Zhu n , Z. Li n, Z. Wang n, J. Li n, X. Mei n, W. Xu *, K. Cheng n, B. Zhong*

author keywords: Osteoporosis; CXCR4; Secretome; Mesenchymal stem cells; Bone targeting; Nanoparticles
MeSH headings : Animals; Cell Membrane / chemistry; Cell Membrane / metabolism; Disease Models, Animal; Endothelial Cells / chemistry; Endothelial Cells / metabolism; Mesenchymal Stem Cells / chemistry; Mesenchymal Stem Cells / metabolism; Nanoparticle Drug Delivery System; Nanoparticles; Osteoporosis / metabolism; Rats; Receptors, CXCR4 / metabolism; Secretome / metabolism
Sources: Web Of Science, ORCID
Added: January 24, 2022

2021 journal article

A Minimally Invasive Exosome Spray Repairs Heart after Myocardial Infarction

ACS NANO, 15(7), 11099–11111.

By: J. Yao*, K. Huang n , D. Zhu n , T. Chen *, Y. Jiang *, J. Zhang *, L. Mi*, H. Xuan ...

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ

Contributors: J. Yao*, K. Huang n , D. Zhu n , T. Chen *, Y. Jiang *, J. Zhang *, L. Mi*, H. Xuan ...

author keywords: MSC; exosome; spray; myocardial infarction; heart repair
MeSH headings : Mice; Swine; Animals; Exosomes; Myocardial Infarction / therapy; Mesenchymal Stem Cells; Heart; Disease Models, Animal
Sources: Web Of Science, ORCID
Added: August 23, 2021

2021 journal article

A fluid-powered refillable origami heart pouch for minimally invasive delivery of cell therapies in rats and pigs

MED, 2(11), 1253-+.

By: X. Mei n, D. Zhu n , J. Li n, K. Huang n , S. Hu n , Z. Li n, B. Abad  n, K. Cheng n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ

Contributors: X. Mei n, D. Zhu n , J. Li n, K. Huang n , S. Hu n , Z. Li n, B. Juan Abad  n, K. Cheng n

MeSH headings : Animals; Cell- and Tissue-Based Therapy; Heart; Mesenchymal Stem Cell Transplantation / methods; Mesenchymal Stem Cells; Myocardial Infarction / surgery; Rats; Swine
Sources: ORCID, Web Of Science
Added: November 3, 2021

2021 journal article

A stem cell-derived ovarian regenerative patch restores ovarian function and rescues fertility in rats with primary ovarian insufficiency

THERANOSTICS, 11(18), 8894–8908.

By: S. Zhang*, D. Zhu* , Z. Li*, K. Huang* , S. Hu* , H. Lutz*, M. Xie*, X. Mei* ...

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ

Contributors: S. Zhang*, D. Zhu* , Z. Li*, K. Huang* , S. Hu* , H. Lutz*, M. Xie*, X. Mei* ...

author keywords: primary ovarian insufficiency; ovarian regenerative patch; regenerative medicine; mesenchymal stem cells; acellular therapy; fertility
MeSH headings : Animals; Apoptosis; Cell-Derived Microparticles / metabolism; Disease Models, Animal; Female; Hydrogels / pharmacology; Infertility, Female / therapy; Mesenchymal Stem Cell Transplantation / methods; Mesenchymal Stem Cells / metabolism; Ovary / pathology; Primary Ovarian Insufficiency / therapy; Rats; Rats, Sprague-Dawley; Regenerative Medicine / methods; Secretome; Stem Cells / metabolism; Tissue Scaffolds
Sources: Web Of Science, ORCID
Added: October 12, 2021

2021 journal article

A trifunctional contraceptive gel enhances the safety and quality of sexual intercourse

BIOACTIVE MATERIALS, 6(6), 1777–1788.

By: M. Xie n, J. Li n, S. Zhang n, D. Zhu n , X. Mei n, Z. Wang n, X. Cheng n, Z. Li n, S. Wang *, K. Cheng n

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ

Contributors: M. Xie n, J. Li n, S. Zhang n, D. Zhu n , X. Mei n, Z. Wang n, X. Cheng n, Z. Li n, S. Wang *, K. Cheng n

author keywords: Contraceptive; Hydrogel; Anti-viral; Libido; Erectile function
Sources: ORCID, Web Of Science
Added: March 6, 2021

2021 review

Advances in biomaterials and regenerative medicine for primary ovarian insufficiency therapy

[Review of ]. BIOACTIVE MATERIALS, 6(7), 1957–1972.

By: S. Zhang n, D. Zhu n , X. Mei n, Z. Li n, J. Li n, M. Xie n, H. Xie, S. Wang *, K. Cheng n

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ

Contributors: S. Zhang n, D. Zhu n , X. Mei n, Z. Li n, J. Li n, M. Xie n, H. Xie, S. Wang *, K. Cheng n

author keywords: Stem cells; Primary ovarian insufficiency; Cell therapy; Biomaterials
Sources: ORCID, Web Of Science
Added: March 6, 2021

2021 review

All Roads Lead to Rome (the Heart): Cell Retention and Outcomes From Various Delivery Routes of Cell Therapy Products to the Heart

[Review of ]. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 10(8).

By: J. Li n, S. Hu n , D. Zhu n , K. Huang n , X. Mei n, B. Abad  n, K. Cheng

co-author countries: United States of America πŸ‡ΊπŸ‡Έ

Contributors: J. Li n, S. Hu n , D. Zhu n , K. Huang n , X. Mei n, B. Abad  n, K. Cheng

author keywords: cardiac repair; cell delivery; intracoronary; intramyocardial; intrapericardial; intravenous; retention rate
MeSH headings : Animals; Cell- and Tissue-Based Therapy / methods; Heart Diseases / therapy; Humans; Injections
Sources: Web Of Science, ORCID
Added: June 10, 2021

2021 journal article

Bioengineering Technologies for Cardiac Regenerative Medicine

Frontiers in Bioengineering and Biotechnology, 9.

By: M. Chingale n, D. Zhu n , K. Cheng n & K. Huang 

co-author countries: United States of America πŸ‡ΊπŸ‡Έ

Contributors: M. Chingale n, D. Zhu n , K. Cheng n & K. Huang 

author keywords: bioengineering; cardiac repair; cell reprogramming; exosome; cardiac patch; targeting
Sources: Web Of Science, ORCID, Crossref
Added: June 28, 2021

2021 journal article

Bispecific Antibody Inhalation Therapy for Redirecting Stem Cells from the Lungs to Repair Heart Injury

Advanced Science, 8(1).

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ
Source: ORCID
Added: April 19, 2023

2021 review

Cardiac Cell Therapy for Heart Repair: Should the Cells Be Left Out?

[Review of ]. CELLS, 10(3).

By: D. Zhu n  & K. Cheng n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ

Contributors: D. Zhu n  & K. Cheng n

author keywords: stem cell; myocardial infarction; cardiovascular diseases; acellular therapy; exosomes; paracrine effects; biomedical engineering; biomaterials
MeSH headings : Cell- and Tissue-Based Therapy / methods; Heart Failure / pathology; Heart Failure / therapy; Humans; Myocardium / pathology; Myocytes, Cardiac / metabolism; Tissue Engineering / methods
Sources: ORCID, Web Of Science
Added: March 15, 2021

2021 journal article

Cell-mimicking nanodecoys neutralize SARS-CoV-2 and mitigate lung injury in a non-human primate model of COVID-19

Nature Nanotechnology, 6(8), 942–951.

By: Z. Li  n, Z. Wang  n, P. Dinh  n, D. Zhu n , K. Popowski n , H. Lutz  n, S. Hu  n, M. Lewis * ...

co-author countries: United States of America πŸ‡ΊπŸ‡Έ

Contributors: Z. Li  n, Z. Wang  n, P. Dinh  n, D. Zhu n , K. Popowski n , H. Lutz  n, S. Hu  n, M. Lewis * ...

MeSH headings : Administration, Inhalation; Angiotensin-Converting Enzyme 2 / metabolism; Animals; COVID-19 / virology; Cell-Derived Microparticles / metabolism; Cell-Derived Microparticles / transplantation; Disease Models, Animal; Humans; Lung Injury / prevention & control; Lung Injury / virology; Macaca fascicularis; Mice; Nanostructures / administration & dosage; Protein Binding; SARS-CoV-2 / drug effects; SARS-CoV-2 / metabolism; Spheroids, Cellular / metabolism; Spike Glycoprotein, Coronavirus / metabolism; Viral Load / drug effects; COVID-19 Drug Treatment
Source: ORCID
Added: June 18, 2021

2021 journal article

Exosome-eluting stents for vascular healing after ischaemic injury

NATURE BIOMEDICAL ENGINEERING, 5(10), 1174–1188.

By: S. Hu n , Z. Li n, D. Shen n, D. Zhu n , K. Huang n , T. Su n, P. Dinh n, J. Cores n, K. Cheng n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ

Contributors: S. Hu n , Z. Li n, D. Shen n, D. Zhu n , K. Huang n , T. Su n, P. Dinh n, J. Cores n, K. Cheng n

MeSH headings : Animals; Drug-Eluting Stents; Endothelial Cells; Endothelium, Vascular; Exosomes; Ischemia; Rats; Stents
Sources: ORCID, Web Of Science
Added: April 6, 2021

2021 journal article

Extruded Mesenchymal Stem Cell Nanovesicles Are Equally Potent to Natural Extracellular Vesicles in Cardiac Repair

ACS APPLIED MATERIALS & INTERFACES, 13(47), 55767–55779.

By: X. Wang *, S. Hu n , J. Li n, D. Zhu n , Z. Wang n, J. Cores n, K. Cheng n, G. Liu *, K. Huang 

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ

Contributors: X. Wang *, S. Hu n , J. Li n, D. Zhu n , Z. Wang n, J. Cores n, K. Cheng n, G. Liu *, K. Huang 

author keywords: extrusion; nanovesicles; extracellular vesicles; mesenchymal stem cell; ischemia reperfusion injury
MeSH headings : Animals; Disease Models, Animal; Endothelial Cells / drug effects; Endothelial Cells / pathology; Extracellular Vesicles / chemistry; Fibroblasts / drug effects; Fibroblasts / pathology; Mesenchymal Stem Cells / chemistry; Mesenchymal Stem Cells / cytology; Mice; Myocardial Infarction / drug therapy; Myocardial Infarction / pathology; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / pathology; Nanoparticles / chemistry; Particle Size; Surface Properties
Sources: Web Of Science, ORCID
Added: February 21, 2022

2021 journal article

Injection of ROS-Responsive Hydrogel Loaded with Basic Fibroblast Growth Factor into the Pericardial Cavity for Heart Repair

ADVANCED FUNCTIONAL MATERIALS, 31(15).

By: Z. Li n, D. Zhu n , Q. Hui *, J. Bi*, B. Yu *, Z. Huang *, S. Hu n , Z. Wang n ...

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ

Contributors: Z. Li n, D. Zhu n , Q. Hui *, J. Bi*, B. Yu *, Z. Huang *, S. Hu n , Z. Wang n ...

author keywords: bFGF; heart repair; intrapericardial delivery; pericardial cavity; ROS responsive hydrogels
Sources: Web Of Science, ORCID
Added: February 22, 2021

2021 journal article

Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair

NATURE COMMUNICATIONS, 12(1).

By: D. Zhu n , Z. Li n, K. Huang n , T. Caranasos *, J. Rossi * & K. Cheng n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ

Contributors: D. Zhu n , Z. Li n, K. Huang n , T. Caranasos *, J. Rossi * & K. Cheng n

MeSH headings : Animals; Cardiac Surgical Procedures; Cardiovascular Agents / administration & dosage; Cell Differentiation / physiology; Drug Delivery Systems / methods; Exosomes / metabolism; Extracellular Matrix / chemistry; Hydrogels / administration & dosage; Hydrogels / chemistry; Induced Pluripotent Stem Cells / transplantation; Male; Materials Testing; Mesenchymal Stem Cells / cytology; Mice; Minimally Invasive Surgical Procedures / methods; Myocardial Infarction / drug therapy; Myocardial Infarction / pathology; Myocardial Infarction / therapy; Myocytes, Cardiac / cytology; Myocytes, Cardiac / physiology; Pericardium; Rats; Swine
Sources: ORCID, Web Of Science
Added: March 6, 2021

2021 journal article

Nitrate-functionalized patch confers cardioprotection and improves heart repair after myocardial infarction via local nitric oxide delivery

Nature Communications, 12(1).

co-author countries: China πŸ‡¨πŸ‡³
MeSH headings : Animals; Cardiotonic Agents / metabolism; Cardiotonic Agents / pharmacology; Disease Models, Animal; Drug Implants / metabolism; Drug Implants / pharmacology; Heart / drug effects; Heart / physiopathology; Macrophage Activation / drug effects; Male; Mice; Myocardial Infarction / metabolism; Myocardial Infarction / mortality; Myocardial Infarction / prevention & control; Myocardial Ischemia / metabolism; Myocardial Ischemia / prevention & control; Myocardial Reperfusion Injury / metabolism; Myocardial Reperfusion Injury / prevention & control; Nitrates / metabolism; Nitrogen Oxides / metabolism; RAW 264.7 Cells; Rats, Sprague-Dawley; Survival Rate; Swine
Source: ORCID
Added: July 24, 2021

2021 journal article

Platelet membrane and stem cell exosome hybrids enhance cellular uptake and targeting to heart injury

NANO TODAY, 39.

By: S. Hu n , X. Wang  n, Z. Li n, D. Zhu n , J. Cores n, Z. Wang n, J. Li n, X. Mei n ...

co-author countries: United States of America πŸ‡ΊπŸ‡Έ

Contributors: S. Hu n , X. Wang  n, Z. Li n, D. Zhu n , J. Cores n, Z. Wang n, J. Li n, X. Mei n ...

author keywords: Exosomes; Targeting; Myocardial infarction; Platelet membrane; Stem cells
Sources: Web Of Science, ORCID
Added: September 7, 2021

2021 journal article

Publisher Correction: Exosome-eluting stents for vascular healing after ischaemic injury

Nature Biomedical Engineering, 5(10), 1239.

By: S. Hu  n, Z. Li  n, D. Shen  n, D. Zhu n , K. Huang n , T. Su n, P. Dinh  n, J. Cores n, K. Cheng  n

co-author countries: United States of America πŸ‡ΊπŸ‡Έ

Contributors: S. Hu  n, Z. Li  n, D. Shen  n, D. Zhu n , K. Huang n , T. Su n, P. Dinh  n, J. Cores n, K. Cheng  n

Source: ORCID
Added: April 21, 2021

2020 journal article

Anti-neuroinflammatory effects of dimethylaminomylide (DMAMCL, i.e., ACT001) are associated with attenuating the NLRP3 inflammasome in MPTP-induced Parkinson disease in mice

Behavioural Brain Research, 383.

By: Q. Liu *, X. Guo *, Z. Huang *, Q. He*, D. Zhu* , S. Zhang*, Z. Peng*, Y. Che*, X. Feng

co-author countries: China πŸ‡¨πŸ‡³

Contributors: Q. Liu *, X. Guo *, Z. Huang *, Q. He*, D. Zhu* , S. Zhang*, Z. Peng*, Y. Che*, X. Feng

MeSH headings : 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Behavior, Animal / drug effects; Catalase / drug effects; Catalase / metabolism; Circadian Rhythm / drug effects; Corpus Striatum / drug effects; Corpus Striatum / metabolism; Corpus Striatum / pathology; Cytokines / drug effects; Cytokines / metabolism; Dopaminergic Neurons / drug effects; Dopaminergic Neurons / metabolism; Dopaminergic Neurons / pathology; Inflammasomes / drug effects; Inflammasomes / metabolism; Inflammation / metabolism; Inflammation / physiopathology; Malondialdehyde / metabolism; Mice; NLR Family, Pyrin Domain-Containing 3 Protein / drug effects; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Oxidative Stress / drug effects; Parkinsonian Disorders / metabolism; Parkinsonian Disorders / physiopathology; Sesquiterpenes, Guaiane / pharmacology; Substantia Nigra / drug effects; Substantia Nigra / metabolism; Substantia Nigra / pathology; Superoxide Dismutase / drug effects; Superoxide Dismutase / metabolism; Tyrosine 3-Monooxygenase / metabolism
Source: ORCID
Added: April 19, 2023

2020 journal article

Delivery of mscs with a hybrid Ξ²-sheet peptide hydrogel consisting igf-1c domain and d-form peptide for acute kidney injury therapy

International Journal of Nanomedicine, 15, 4311–4324.

co-author countries: China πŸ‡¨πŸ‡³
MeSH headings : Acute Kidney Injury / drug therapy; Acute Kidney Injury / physiopathology; Animals; Biocompatible Materials / chemistry; Cell Survival; Female; Fibrosis; Human Umbilical Vein Endothelial Cells / metabolism; Humans; Hydrogels / chemical synthesis; Hydrogels / chemistry; Insulin-Like Growth Factor I / chemistry; Kidney / pathology; Kidney / physiopathology; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells / cytology; Mice, Transgenic; Neovascularization, Physiologic; Peptides / chemistry; Placenta / cytology; Pregnancy; Protein Conformation, beta-Strand; Protein Domains
Source: ORCID
Added: April 19, 2023

2020 journal article

Effects of 17Ξ²-trenbolone exposure on sex hormone synthesis and social behaviours in adolescent mice

Chemosphere, 245.

By: S. Zhang*, S. Zhang *, D. Zhu* , Z. Jiao *, X. Zhao *, M. Sun *, Y. Che*, X. Feng *

co-author countries: China πŸ‡¨πŸ‡³

Contributors: S. Zhang*, S. Zhang *, D. Zhu* , Z. Jiao *, X. Zhao *, M. Sun *, Y. Che*, X. Feng *

MeSH headings : Animals; Anxiety / chemically induced; Avoidance Learning / drug effects; Endocrine Disruptors / pharmacology; Gonadal Steroid Hormones / biosynthesis; Male; Mice; Myelin Sheath / drug effects; Oligodendroglia / drug effects; Social Behavior; Trenbolone Acetate / pharmacology
Source: ORCID
Added: April 19, 2023

2020 journal article

Light-triggered NO-releasing nanoparticles for treating mice with liver fibrosis

NANO RESEARCH, 13(8), 2197–2202.

By: H. Liang*, Z. Li n, Z. Ren *, Q. Jia*, L. Guo *, S. Li *, H. Zhang *, S. Hu n  ...

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ

Contributors: H. Liang*, Z. Li n, Z. Ren *, Q. Jia*, L. Guo *, S. Li *, H. Zhang *, S. Hu n  ...

author keywords: liver fibrosis; nitric oxide (NO); hepatic stellate cells (HSC); nanoparticles; near infrared light (NIR)-controlled release
Sources: ORCID, Web Of Science
Added: June 29, 2020

2020 journal article

Multifunctional natural polymer nanoparticles as antifibrotic gene carriers for CKD therapy

Journal of the American Society of Nephrology, 31(10), 2292–2311.

By: A. Midgley *, Y. Wei*, D. Zhu* , F. Gao*, H. Yan *, A. Khalique*, W. Luo *, H. Jiang * ...

co-author countries: China πŸ‡¨πŸ‡³

Contributors: A. Midgley *, Y. Wei*, D. Zhu* , F. Gao*, H. Yan *, A. Khalique*, W. Luo *, H. Jiang * ...

MeSH headings : Animals; Antifibrinolytic Agents / administration & dosage; Bone Morphogenetic Protein 7 / genetics; Cell Culture Techniques; Chitosan; Disease Models, Animal; Gene Transfer Techniques; Hepatocyte Growth Factor / genetics; Hyaluronic Acid; Mice; Multifunctional Nanoparticles; Polymers; Renal Insufficiency, Chronic / therapy
Source: ORCID
Added: April 19, 2023

2020 journal article

Particle-based artificial three-dimensional stem cell spheroids for revascularization of ischemic diseases

Science Advances, 6(19).

co-author countries: China πŸ‡¨πŸ‡³
Source: ORCID
Added: March 6, 2021

2020 journal article

Supramolecular Nanofibers Containing Arginine-Glycine-Aspartate (RGD) Peptides Boost Therapeutic Efficacy of Extracellular Vesicles in Kidney Repair

ACS Nano, 14(9), 12133–12147.

co-author countries: China πŸ‡¨πŸ‡³
MeSH headings : Animals; Arginine; Aspartic Acid; Extracellular Vesicles; Glycine; Kidney; Mice; Nanofibers; Oligopeptides
Source: ORCID
Added: April 19, 2023

2020 journal article

Targeted Repair of Vascular Injury by Adipose-Derived Stem Cells Modified with P-Selectin Binding Peptide

Advanced Science, 7(11).

By: H. Yan *, X. Mi*, A. Midgley *, X. Du*, Z. Huang *, T. Wei *, R. Liu *, T. Ma* ...

co-author countries: China πŸ‡¨πŸ‡³

Contributors: H. Yan *, X. Mi*, A. Midgley *, X. Du*, Z. Huang *, T. Wei *, R. Liu *, T. Ma* ...

Source: ORCID
Added: April 19, 2023

2020 journal article

The parthenolide derivative ACT001 synergizes with low doses of L-DOPA to improve MPTP-induced Parkinson's disease in mice

Behavioural Brain Research, 379.

By: Q. Liu *, S. Zhang*, D. Zhu* , X. Tang *, Y. Che* & X. Feng

co-author countries: China πŸ‡¨πŸ‡³

Contributors: Q. Liu *, S. Zhang*, D. Zhu* , X. Tang *, Y. Che* & X. Feng

MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / pharmacology; Antiparkinson Agents / administration & dosage; Antiparkinson Agents / pharmacology; Apoptosis / drug effects; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Inflammation / drug therapy; Levodopa; Male; Mice; Mice, Inbred BALB C; Nerve Degeneration / drug therapy; Parkinson Disease / drug therapy; Parkinsonian Disorders / drug therapy; Sesquiterpenes / administration & dosage; Sesquiterpenes / analysis; Sesquiterpenes / pharmacology
Source: ORCID
Added: April 19, 2023

2019 journal article

A collagen hydrogel loaded with HDAC7-derived peptide promotes the regeneration of infarcted myocardium with functional improvement in a rodent model

Acta Biomaterialia, 86, 223–234.

By: Y. Zhang *, D. Zhu* , Y. Wei*, Y. Wu *, W. Cui *, L. Liuqin*, G. Fan *, Q. Yang * ...

co-author countries: China πŸ‡¨πŸ‡³ United Kingdom of Great Britain and Northern Ireland πŸ‡¬πŸ‡§

Contributors: Y. Zhang *, D. Zhu* , Y. Wei*, Y. Wu *, W. Cui *, L. Liuqin*, G. Fan *, Q. Yang * ...

MeSH headings : Animals; Apoptosis / drug effects; Cell Differentiation / drug effects; Cell Survival / drug effects; Collagen / pharmacology; Culture Media, Serum-Free; Disease Models, Animal; Female; Histone Deacetylases / chemistry; Hydrogels / pharmacology; Mice, Inbred C57BL; Myocardial Infarction / physiopathology; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / pathology; Neovascularization, Physiologic / drug effects; Peptides / pharmacology; Rats; Recovery of Function / drug effects; Regeneration / drug effects; Stem Cells / cytology; Stem Cells / drug effects; Ventricular Function / drug effects
Source: ORCID
Added: April 19, 2023

2019 article

Delivery of MSCs with a Hybrid Ξ²-Sheet Peptide Hydrogel Consisting IGF-1C Domain and D-Form Peptide for Acute Kidney Injury Therapy

SSRN.

co-author countries: China πŸ‡¨πŸ‡³
Source: ORCID
Added: April 19, 2023

2019 journal article

Lactobacillus maintains healthy gut mucosa by producing L-Ornithine

Communications Biology, 2(1).

By: H. Qi*, Y. Li *, H. Yun*, T. Zhang *, Y. Huang *, J. Zhou *, H. Yan *, J. Wei * ...

co-author countries: China πŸ‡¨πŸ‡³

Contributors: H. Qi*, Y. Li *, H. Yun*, T. Zhang *, Y. Huang *, J. Zhou *, H. Yan *, J. Wei * ...

MeSH headings : Animals; Basic Helix-Loop-Helix Transcription Factors / metabolism; Epithelial Cells / immunology; Epithelial Cells / metabolism; Epithelial Cells / microbiology; Female; Gastrointestinal Microbiome / immunology; Gastrointestinal Microbiome / physiology; Germ-Free Life; Homeostasis; Humans; Intestinal Mucosa / immunology; Intestinal Mucosa / metabolism; Intestinal Mucosa / microbiology; Lactobacillus / immunology; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mucus / metabolism; Nuclear Receptor Subfamily 1, Group F, Member 3 / metabolism; Ornithine / biosynthesis; Pancreatitis-Associated Proteins / genetics; Pancreatitis-Associated Proteins / metabolism; Receptors, Aryl Hydrocarbon / metabolism
Source: ORCID
Added: April 19, 2023

2019 journal article

Preparation of levodopa-loaded crystalsomes through thermally induced crystallization reverses functional deficits in Parkinsonian mice

Biomaterials Science, 7(4), 1623–1631.

By: X. Li *, Q. Liu *, D. Zhu* , Y. Che* & X. Feng

co-author countries: China πŸ‡¨πŸ‡³

Contributors: X. Li *, Q. Liu *, D. Zhu* , Y. Che* & X. Feng

MeSH headings : Animals; Antiparkinson Agents / chemical synthesis; Antiparkinson Agents / chemistry; Antiparkinson Agents / therapeutic use; Crystallization; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers / chemistry; Emulsions / chemical synthesis; Emulsions / chemistry; Emulsions / therapeutic use; Female; Levodopa / chemical synthesis; Levodopa / chemistry; Levodopa / therapeutic use; Mice; Mice, Inbred BALB C; Molecular Structure; Nanoparticles / chemistry; Parkinson Disease / drug therapy; Structure-Activity Relationship; Temperature
Source: ORCID
Added: April 19, 2023

2019 journal article

Resveratrol synergizes with low doses of L-DOPA to improve MPTP-induced Parkinson disease in mice

Behavioural Brain Research, 367, 10–18.

By: Q. Liu *, D. Zhu* , P. Jiang*, X. Tang *, Q. Lang*, Q. Yu*, S. Zhang*, Y. Che*, X. Feng *

co-author countries: China πŸ‡¨πŸ‡³

Contributors: Q. Liu *, D. Zhu* , P. Jiang*, X. Tang *, Q. Lang*, Q. Yu*, S. Zhang*, Y. Che*, X. Feng *

MeSH headings : Animals; Antioxidants / administration & dosage; Antioxidants / pharmacology; Antiparkinson Agents / administration & dosage; Antiparkinson Agents / pharmacology; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Levodopa / administration & dosage; Levodopa / pharmacology; MPTP Poisoning / drug therapy; Mice; Mice, Inbred BALB C; Resveratrol / administration & dosage; Resveratrol / pharmacology
Source: ORCID
Added: April 19, 2023

2019 journal article

Targeted delivery of nitric oxide via a β€˜bump-and-hole’-based enzyme–prodrug pair

Nature Chemical Biology, 15(2), 151–160.

By: J. Hou *, Y. Pan*, D. Zhu* , Y. Fan *, G. Feng*, Y. Wei*, H. Wang *, K. Qin * ...

co-author countries: China πŸ‡¨πŸ‡³ United States of America πŸ‡ΊπŸ‡Έ

Contributors: J. Hou *, Y. Pan*, D. Zhu* , Y. Fan *, G. Feng*, Y. Wei*, H. Wang *, K. Qin * ...

MeSH headings : Animals; Azo Compounds; Drug Delivery Systems / methods; Galactosidases; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Nitric Oxide / administration & dosage; Nitric Oxide / metabolism; Nitric Oxide / physiology; Prodrugs; Rats; Rats, Sprague-Dawley; beta-Galactosidase / metabolism; beta-Galactosidase / physiology
Source: ORCID
Added: April 19, 2023

2018 journal article

Expression and clinical significance of CXC-chemokine ligand 5 in renal cell carcinoma

Chinese Journal of Clinical Oncology, 45(16), 838–843.

By: G. Feng*, H. Li *, D. Zhu* , Y. Zhang*, G. Song *, Z. Zhang *, M. Chen *, J. Du *, X. Yao

co-author countries: China πŸ‡¨πŸ‡³

Contributors: G. Feng*, H. Li *, D. Zhu* , Y. Zhang*, G. Song *, Z. Zhang *, M. Chen *, J. Du *, X. Yao

Source: ORCID
Added: April 19, 2023

2018 journal article

In situ cardiac regeneration by using neuropeptide substance P and IGF-1C peptide eluting heart patches

Regenerative Biomaterials, 5(5), 303–316.

co-author countries: China πŸ‡¨πŸ‡³ Korea (Republic of) πŸ‡°πŸ‡· Pakistan πŸ‡΅πŸ‡°
Source: ORCID
Added: April 19, 2023

2018 journal article

Prostaglandin E2 hydrogel improves cutaneous wound healing via M2 macrophages polarization

Theranostics, 8(19), 5348–5361.

By: S. Zhang *, Y. Liu *, X. Zhang *, D. Zhu* , X. Qi *, X. Cao *, Y. Fang*, Y. Che* ...

co-author countries: China πŸ‡¨πŸ‡³

Contributors: S. Zhang *, Y. Liu *, X. Zhang *, D. Zhu* , X. Qi *, X. Cao *, Y. Fang*, Y. Che* ...

MeSH headings : Animals; Cells, Cultured; Chitosan / administration & dosage; Dinoprostone / administration & dosage; Disease Models, Animal; Drug Carriers / administration & dosage; Hydrogel, Polyethylene Glycol Dimethacrylate / administration & dosage; Immunologic Factors / administration & dosage; Inflammation / pathology; Luminescent Measurements; Macrophage Activation / drug effects; Macrophages, Peritoneal / drug effects; Macrophages, Peritoneal / immunology; Mice; Molecular Imaging; Neovascularization, Physiologic / drug effects; Treatment Outcome; Wound Healing / drug effects; Wounds and Injuries / therapy
Source: ORCID
Added: April 19, 2023

2017 journal article

Herbal formula Xian-Fang-Huo-Ming-Yin regulates differentiation of lymphocytes and production of pro-inflammatory cytokines in collagen-induced arthritis mice

BMC Complementary and Alternative Medicine, 17(1).

By: J. Li *, Y. Wei*, X. Li *, D. Zhu* , B. Nie *, J. Zhou *, L. Lou *, B. Dong * ...

co-author countries: China πŸ‡¨πŸ‡³

Contributors: J. Li *, Y. Wei*, X. Li *, D. Zhu* , B. Nie *, J. Zhou *, L. Lou *, B. Dong * ...

MeSH headings : Animals; Arthritis / drug therapy; Arthritis / genetics; Arthritis / immunology; Arthritis / physiopathology; Cell Differentiation; Collagen / adverse effects; Cytokines / genetics; Cytokines / immunology; Disease Models, Animal; Drugs, Chinese Herbal / administration & dosage; Humans; Janus Kinases / genetics; Janus Kinases / immunology; Lymphocytes / cytology; Lymphocytes / immunology; Male; Mice; Mice, Inbred DBA; NF-kappa B / genetics; NF-kappa B / immunology
Source: ORCID
Added: April 19, 2023

2017 journal article

PEGylation corannulene enhances response of stress through promoting neurogenesis

Biomaterials Science, 5(4), 849–859.

co-author countries: China πŸ‡¨πŸ‡³

Contributors: X. Li *, D. Sun *, X. Li *, D. Zhu* , Z. Jia *, J. Jiao*, K. Wang *, D. Kong * ...

MeSH headings : Animals; Doublecortin Protein; Female; Locomotion / drug effects; Mice; Mice, Inbred BALB C; Nanoparticles / chemistry; Nanoparticles / ultrastructure; Neurogenesis / drug effects; Polycyclic Aromatic Hydrocarbons / chemistry; Polycyclic Aromatic Hydrocarbons / pharmacology; Polyethylene Glycols / chemistry; Polyethylene Glycols / pharmacology; Stress, Physiological / drug effects
Source: ORCID
Added: April 19, 2023

2017 journal article

Puerarin and Amlodipine Improvement of d-Galactose-Induced Impairments of Behaviour and Neurogenesis in Mouse Dentate Gyrus: Correlation with Glucocorticoid Receptor Expression

Neurochemical Research, 42(11), 3268–3278.

By: X. Li *, J. Ma *, J. Xu *, D. Zhu* , A. Li*, Y. Che*, D. Chen *, X. Feng *

co-author countries: China πŸ‡¨πŸ‡³

Contributors: X. Li *, J. Ma *, J. Xu *, D. Zhu* , A. Li*, Y. Che*, D. Chen *, X. Feng *

MeSH headings : Aging / drug effects; Aging / metabolism; Aging / pathology; Amlodipine / administration & dosage; Animals; Dentate Gyrus / drug effects; Dentate Gyrus / metabolism; Dentate Gyrus / pathology; Doublecortin Protein; Drug Therapy, Combination; Female; Galactose / toxicity; Gene Expression; Isoflavones / administration & dosage; Maze Learning / drug effects; Maze Learning / physiology; Mice; Mice, Inbred BALB C; Neurogenesis / drug effects; Neurogenesis / physiology; Receptors, Glucocorticoid / biosynthesis; Receptors, Glucocorticoid / genetics; Vasodilator Agents / administration & dosage
Source: ORCID
Added: April 19, 2023

2017 journal article

Rhein and polydimethylsiloxane functionalized carbon/carbon composites as prosthetic implants for bone repair applications

Biomedical Materials (Bristol), 12(4).

By: Z. Jia *, C. Yang *, J. Jiao*, X. Li *, D. Zhu* , Y. Yang *, J. Yang *, Y. Che*, Y. Lu *, X. Feng

co-author countries: China πŸ‡¨πŸ‡³

Contributors: Z. Jia *, C. Yang *, J. Jiao*, X. Li *, D. Zhu* , Y. Yang *, J. Yang *, Y. Che*, Y. Lu *, X. Feng

MeSH headings : Anthraquinones / chemistry; Anthraquinones / metabolism; Biocompatible Materials / chemistry; Bone and Bones / chemistry; Bone and Bones / physiology; Cell Adhesion; Dimethylpolysiloxanes / chemistry; Nanotubes, Carbon / chemistry; Prostheses and Implants; Tissue Engineering / methods
Source: ORCID
Added: April 19, 2023

2016 journal article

IGF-1 C domain-modified hydrogel enhances cell therapy for AKI

Journal of the American Society of Nephrology, 27(8), 2357–2369.

By: G. Feng*, J. Zhang *, Y. Li, Y. Nie, D. Zhu* , R. Wang, J. Liu *, J. Gao * ...

co-author countries: China πŸ‡¨πŸ‡³

Contributors: G. Feng*, J. Zhang *, Y. Li, Y. Nie, D. Zhu* , R. Wang, J. Liu *, J. Gao * ...

MeSH headings : Acute Kidney Injury / therapy; Adipose Tissue / cytology; Animals; Chitosan; Combined Modality Therapy; Hydrogel, Polyethylene Glycol Dimethacrylate; Insulin-Like Growth Factor I / administration & dosage; Mesenchymal Stem Cell Transplantation; Mice
Source: ORCID
Added: April 19, 2023

Employment

Updated: December 13th, 2023 13:53

2023 - present

Columbia University New York, US
Postdoc Research Scientist Biomedical Engineering

2019 - 2023

UNC/NCSU Joint Department of Biomedical Engineering Raleigh, NC, US
Joint Department of Biomedical Engineering

2019 - 2023

NC State University Raleigh, NC, US

Education

Updated: February 13th, 2020 21:16

Nankai University Tianjin, CN

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