Works (26)

2023 article

An inhaled bioadhesive hydrogel to shield non-human primates from SARS-CoV-2 infection

Mei, X., Li, J., Wang, Z., Zhu, D., Huang, K., Hu, S., … Cheng, K. (2023, February 9). NATURE MATERIALS, Vol. 2.

By: X. Mei, J. Li, Z. Wang, D. Zhu, K. Huang, S. Hu, K. Popowski, K. Cheng

Sources: Web Of Science, ORCID
Added: March 6, 2023

2022 article

Decoy Exosomes Offer Protection Against Chemotherapy-Induced Toxicity

Fan, M., Li, H., Shen, D., Wang, Z., Liu, H., Zhu, D., … Li, Z. (2022, September 4). ADVANCED SCIENCE, Vol. 9.

By: M. Fan*, H. Li*, D. Shen*, Z. Wang*, H. Liu*, D. Zhu, Z. Wang, L. Li* ...

author keywords: cardio-oncology; cardiotoxicity; chemotherapy; exosome; tetrahedral DNA nanostructure
Sources: Web Of Science, ORCID
Added: September 12, 2022

2022 article

Detachable Microneedle Patches Deliver Mesenchymal Stromal Cell Factor-Loaded Nanoparticles for Cardiac Repair

Hu, S., Zhu, D., Li, Z., & Cheng, K. (2022, September 23). ACS NANO, Vol. 9.

By: S. Hu, D. Zhu, Z. Li & K. Cheng

author keywords: mesenchymal stromal cell; secreted factors; microneedle patch; elastin-like peptide gel; hyaluronic acid gel; myocardial infarction; cardiac repair
Sources: Web Of Science, ORCID
Added: October 11, 2022

2022 article

Exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain as an inhalable COVID-19 vaccine

Wang, Z., Popowski, K. D., Zhu, D., Abad, B. L. de J., Wang, X., Liu, M., … Cheng, K. (2022, July 4). NATURE BIOMEDICAL ENGINEERING, Vol. 7.

By: Z. Wang, K. Popowski, D. Zhu, B. Abad n, X. Wang n, M. Liu, H. Lutz, N. De Naeyer* ...

Sources: Web Of Science, ORCID
Added: July 11, 2022

2022 journal article

Inhalable dry powder mRNA vaccines based on extracellular vesicles

MATTER, 5(9), 2960–2974.

By: K. Popowski, A. Moatti, G. Scull, D. Silkstone, H. Lutz, B. Abad n, A. George, E. Belcher* ...

Sources: Web Of Science, ORCID
Added: October 17, 2022

2022 journal article

Intrapericardial Exosome Therapy Dampens Cardiac Injury via Activating Foxo3

CIRCULATION RESEARCH, 131(10), E135–E150.

By: D. Zhu, S. Liu, K. Huang, Z. Wang, S. Hu, J. Li, Z. Li, K. Cheng

author keywords: exosomes; immunomodulation; mesesnchymal stem cell; myocardial infarction; regulatory T cell
Sources: Web Of Science, ORCID
Added: November 14, 2022

2022 journal article

Intrapericardial hydrogel injection generates high cell retention and augments therapeutic effects of mesenchymal stem cells in myocardial infarction

CHEMICAL ENGINEERING JOURNAL, 427.

By: J. Li, Y. Lv, D. Zhu, X. Mei, K. Huang, X. Wang n, Z. Li, S. Zhang ...

author keywords: Mesenchymal stem cells; Hydrogel; Myocardial infarction; Intrapericardial; Intramyocardial
Sources: Web Of Science, ORCID
Added: January 3, 2022

2022 journal article

Minimally invasive delivery of a hydrogel-based exosome patch to prevent heart failure

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY, 169, 113–121.

By: G. Cheng, D. Zhu, K. Huang & T. Caranasos*

Sources: Web Of Science, ORCID
Added: October 31, 2022

2022 journal article

Nanoparticles functionalized with stem cell secretome and CXCR4-overexpressing endothelial membrane for targeted osteoporosis therapy

JOURNAL OF NANOBIOTECHNOLOGY, 20(1).

author keywords: Osteoporosis; CXCR4; Secretome; Mesenchymal stem cells; Bone targeting; Nanoparticles
Sources: Web Of Science, ORCID
Added: January 24, 2022

2021 journal article

A Minimally Invasive Exosome Spray Repairs Heart after Myocardial Infarction

ACS NANO, 15(7), 11099–11111.

By: J. Yao*, K. Huang, D. Zhu, T. Chen*, Y. Jiang*, J. Zhang*, L. Mi*, H. Xuan* ...

author keywords: MSC; exosome; spray; myocardial infarction; heart repair
Sources: Web Of Science, ORCID
Added: August 23, 2021

2021 journal article

A fluid-powered refillable origami heart pouch for minimally invasive delivery of cell therapies in rats and pigs

MED, 2(11), 1253-+.

Sources: ORCID, Web Of Science
Added: November 3, 2021

2021 journal article

A stem cell-derived ovarian regenerative patch restores ovarian function and rescues fertility in rats with primary ovarian insufficiency

THERANOSTICS, 11(18), 8894–8908.

By: S. Zhang, D. Zhu, Z. Li, K. Huang, S. Hu, H. Lutz, M. Xie, X. Mei ...

author keywords: primary ovarian insufficiency; ovarian regenerative patch; regenerative medicine; mesenchymal stem cells; acellular therapy; fertility
Sources: Web Of Science, ORCID
Added: October 12, 2021

2021 journal article

A trifunctional contraceptive gel enhances the safety and quality of sexual intercourse

BIOACTIVE MATERIALS, 6(6), 1777–1788.

author keywords: Contraceptive; Hydrogel; Anti-viral; Libido; Erectile function
Sources: ORCID, Web Of Science
Added: March 6, 2021

2021 review

Advances in biomaterials and regenerative medicine for primary ovarian insufficiency therapy

[Review of ]. BIOACTIVE MATERIALS, 6(7), 1957–1972.

By: S. Zhang, D. Zhu, X. Mei, Z. Li, J. Li, M. Xie, H. Xie, S. Wang*, K. Cheng

author keywords: Stem cells; Primary ovarian insufficiency; Cell therapy; Biomaterials
Sources: ORCID, Web Of Science
Added: March 6, 2021

2021 review

All Roads Lead to Rome (the Heart): Cell Retention and Outcomes From Various Delivery Routes of Cell Therapy Products to the Heart

[Review of ]. JOURNAL OF THE AMERICAN HEART ASSOCIATION, 10(8).

By: J. Li, S. Hu, D. Zhu, K. Huang, X. Mei, B. Abad n, K. Cheng

author keywords: cardiac repair; cell delivery; intracoronary; intramyocardial; intrapericardial; intravenous; retention rate
Sources: Web Of Science, ORCID
Added: June 10, 2021

2021 review

Bioengineering Technologies for Cardiac Regenerative Medicine

[Review of ]. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 9.

By: M. Chingale, D. Zhu, K. Cheng & K. Huang

author keywords: bioengineering; cardiac repair; cell reprogramming; exosome; cardiac patch; targeting
Sources: Web Of Science, ORCID
Added: June 28, 2021

2021 review

Cardiac Cell Therapy for Heart Repair: Should the Cells Be Left Out?

[Review of ]. CELLS, 10(3).

By: D. Zhu & K. Cheng

author keywords: stem cell; myocardial infarction; cardiovascular diseases; acellular therapy; exosomes; paracrine effects; biomedical engineering; biomaterials
Sources: ORCID, Web Of Science
Added: March 15, 2021

2021 journal article

Cell-mimicking nanodecoys neutralize SARS-CoV-2 and mitigate lung injury in a non-human primate model of COVID-19

Nature Nanotechnology, 6.

Source: ORCID
Added: June 18, 2021

2021 journal article

Exosome-eluting stents for vascular healing after ischaemic injury

NATURE BIOMEDICAL ENGINEERING, 5(10), 1174–1188.

Sources: ORCID, Web Of Science
Added: April 6, 2021

2021 journal article

Extruded Mesenchymal Stem Cell Nanovesicles Are Equally Potent to Natural Extracellular Vesicles in Cardiac Repair

ACS APPLIED MATERIALS & INTERFACES, 13(47), 55767–55779.

author keywords: extrusion; nanovesicles; extracellular vesicles; mesenchymal stem cell; ischemia reperfusion injury
Sources: Web Of Science, ORCID
Added: February 21, 2022

2021 journal article

Injection of ROS-Responsive Hydrogel Loaded with Basic Fibroblast Growth Factor into the Pericardial Cavity for Heart Repair

ADVANCED FUNCTIONAL MATERIALS, 31(15).

By: Z. Li, D. Zhu, Q. Hui*, J. Bi*, B. Yu*, Z. Huang*, S. Hu, Z. Wang ...

author keywords: bFGF; heart repair; intrapericardial delivery; pericardial cavity; ROS responsive hydrogels
Sources: Web Of Science, ORCID
Added: February 22, 2021

2021 journal article

Minimally invasive delivery of therapeutic agents by hydrogel injection into the pericardial cavity for cardiac repair

NATURE COMMUNICATIONS, 12(1).

Sources: ORCID, Web Of Science
Added: March 6, 2021

2021 journal article

Nitrate-functionalized patch confers cardioprotection and improves heart repair after myocardial infarction via local nitric oxide delivery

Nature Communications.

By: D. Zhu, J. Hou*, M. Qian*, D. Jin*, T. Hao*, Y. Pan*, H. Wang*, S. Wu* ...

Source: ORCID
Added: July 24, 2021

2021 journal article

Platelet membrane and stem cell exosome hybrids enhance cellular uptake and targeting to heart injury

NANO TODAY, 39.

By: S. Hu, X. Wang n, Z. Li, D. Zhu, J. Cores, Z. Wang, J. Li, X. Mei ...

author keywords: Exosomes; Targeting; Myocardial infarction; Platelet membrane; Stem cells
Sources: Web Of Science, ORCID
Added: September 7, 2021

2021 journal article

Publisher Correction: Exosome-eluting stents for vascular healing after ischaemic injury

Nature Biomedical Engineering, 4.

Source: ORCID
Added: April 21, 2021

2020 journal article

Particle-based artificial three-dimensional stem cell spheroids for revascularization of ischemic diseases

Science Advances, 6(19).

By: R. Zhang*, W. Luo*, Y. Zhang*, D. Zhu, A. Midgley*, H. Song*, A. Khalique*, H. Zhang* ...

Source: ORCID
Added: March 6, 2021

Employment

UNC/NCSU Joint Department of Biomedical Engineering Raleigh, NC, US
Joint Department of Biomedical Engineering

North Carolina State University Raleigh, NC, US

Education

Nankai University Tianjin, CN