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Works (10)
Updated: April 5th, 2024 10:32
2024 journal article
Characteristics of antimicrobial resistance in <i>Escherichia coli</i> isolated from retail meat products in North Carolina
PLOS ONE, 19(1).
TL;DR:
The lack of an association between MDR E. coli in retail meat and antibiotic use claim, including those with no indication of antimicrobial use, suggests that additional research is required to understand the origin of resistance.
(via Semantic Scholar)
journals.plos.org (publisher PDF)
Sources: Web Of Science, NC State University Libraries
Added: February 26, 2024
2024 journal article
Phenotypic and Genotypic Characterizations of Antimicrobial-Resistant <i>Escherichia coli</i> Isolates from Diverse Retail Meat Samples in North Carolina During 2018-2019
FOODBORNE PATHOGENS AND DISEASE, 1.
author keywords: antimicrobial resistance; Escherichia coli; retail meats; whole genome sequencing; antimicrobial susceptibility testing; multidrug resistance
Sources: Web Of Science, NC State University Libraries
Added: March 18, 2024
2023 journal article
Detection of resistance and virulence plasmids in Campylobacter coli and Campylobacter jejuni isolated from North Carolina food animal production, 2018-2019
FOOD MICROBIOLOGY, 116.
author keywords: Antimicrobial resistance; Food -borne pathogen; Horizontal gene transfer; Transposons; Bioinformatics
TL;DR:
This study highlights the extensive distribution and diversity of Campylobacter plasmids in food animal production and their role in the dissemination of biomedically important genes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: October 2, 2023
2022 journal article
Multidrug resistance and virulence genes carried by mobile genomic elements in Salmonella enterica isolated from live food animals, processed, and retail meat in North Carolina, 2018-2019
INTERNATIONAL JOURNAL OF FOOD MICROBIOLOGY, 378.
author keywords: Whole-genome sequencing; Plasmid assembly; Bioinformatics; Pathogen fitness; Food safety
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Cattle; Drug Resistance, Multiple, Bacterial / genetics; Genomics; Humans; Meat; Microbial Sensitivity Tests; North Carolina; Plasmids; Poultry; Salmonella Infections; Salmonella enterica; Swine; Virulence / genetics; Virulence Factors / genetics
TL;DR:
Plasmid-mediated virulence factors also appear to provide a fitness advantage, as the dominant S. enterica serotype Kentucky in chicken retail meat held the greatest diversity of plasmID-mediated colicin virulence genes which are often upregulated by environmental stressors and confer a competitive advantage.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 15, 2022
2022 journal article
Toward the Adoption of Loop-Mediated Isothermal Amplification for Salmonella Screening at the National Antimicrobial Resistance Monitoring System's Retail Meat Sites
FOODBORNE PATHOGENS AND DISEASE, 19(11), 758–766.
author keywords: antimicrobial resistance; LAMP; NARMS; Salmonella; screening; monitoring
MeSH headings : Humans; Animals; United States; Anti-Bacterial Agents / pharmacology; Drug Resistance, Bacterial / genetics; Salmonella; Meat / microbiology; Microbial Sensitivity Tests
TL;DR:
A method comparison study clearly demonstrated the benefit of a rapid, robust, and highly sensitive molecular screening method in streamlining the laboratory workflow.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 1, 2023
2021 journal article
Antimicrobial resistance and interspecies gene transfer in Campylobacter coli and Campylobacter jejuni isolated from food animals, poultry processing, and retail meat in North Carolina, 2018-2019
PLOS ONE, 16(2).
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacterial Proteins / genetics; Campylobacter coli / drug effects; Campylobacter coli / genetics; Campylobacter coli / isolation & purification; Campylobacter jejuni / drug effects; Campylobacter jejuni / genetics; Campylobacter jejuni / isolation & purification; Drug Resistance, Bacterial; Gene Transfer, Horizontal; Meat / microbiology; North Carolina; Poultry / microbiology
TL;DR:
Evidence of C. coli and C. jejuni interspecies genomic exchange may aid pathogen adaption, lead to higher AMR and increase Campylobacter persistence in food processing is investigated to track evolving risks to public health.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: March 15, 2021
2021 journal article
Tumor Necrosis Factor Alpha-Induced Interleukin-1 Alpha Synthesis and Cell Death Is Increased in Mouse Epithelial Cells Infected With Chlamydia muridarum
JOURNAL OF INFECTIOUS DISEASES, 224, S47–S55.
author keywords: Chlamydia muridarum; IL-1 alpha; mouse epithelial cells; mouse model; TNF alpha
MeSH headings : Animals; Cell Death; Chlamydia Infections / immunology; Chlamydia Infections / metabolism; Chlamydia muridarum / immunology; Epithelial Cells; Female; Interleukin-1alpha / immunology; Interleukin-1alpha / metabolism; Mice; Mice, Inbred C57BL; Tumor Necrosis Factor-alpha / immunology; Tumor Necrosis Factor-alpha / metabolism
TL;DR:
The results suggest TNFα and IL-1α enhance each other's downstream effects resulting in a hyperinflammatory response to chlamydial infection and propose that biologics targeting TNF-induced IL- 1α synthesis could be used to mitigate tissue damage during chlamYDial infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 13, 2021
2020 journal article
Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis
NATURE COMMUNICATIONS, 11(1).
MeSH headings : Administration, Inhalation; Alveolar Epithelial Cells / drug effects; Alveolar Epithelial Cells / metabolism; Alveolar Epithelial Cells / pathology; Animals; Apoptosis / drug effects; Bleomycin / toxicity; Cell Proliferation; Disease Models, Animal; Exosomes / metabolism; Exosomes / transplantation; Humans; Idiopathic Pulmonary Fibrosis / chemically induced; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Idiopathic Pulmonary Fibrosis / therapy; Lung / cytology; Lung / metabolism; Lung Injury / chemically induced; Lung Injury / metabolism; Lung Injury / pathology; Lung Injury / therapy; Mesenchymal Stem Cells / metabolism; Mice; Myofibroblasts / cytology; Proteomics; Silicon Dioxide / toxicity; Spheroids, Cellular / metabolism
TL;DR:
It is shown that the secretome and exosomes of lung spheroid cells is effective as inhalation treatment in rodent models of lung injury and fibrosis and superior to the counterparts derived from mesenchymal stem cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 23, 2020
2019 journal article
Fc Characteristics Mediate Selective Placental Transfer of IgG in HIV-Infected Women
CELL, 178(1), 190-+.
MeSH headings : Cohort Studies; Disease Progression; Female; Glycosylation; HIV / genetics; HIV Infections / immunology; HIV Infections / transmission; HIV Infections / virology; Humans; Immunoglobulin Fc Fragments / metabolism; Immunoglobulin G / blood; Infant; Infant, Newborn; Infectious Disease Transmission, Vertical; Malawi; Placenta / metabolism; Pregnancy; Pregnancy Complications, Infectious / immunology; Pregnancy Complications, Infectious / virology; Receptors, IgG / metabolism; United States; Viral Load / genetics
TL;DR:
It is suggested that Fc region characteristics modulate the selective placental transfer of IgG, with implications for maternal vaccine design and infant health.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 15, 2019
2017 review
Elucidating the role of host long non-coding RNA during viral infection: Challenges and paths forward
[Review of ]. Vaccines, 5(4).
Source: NC State University Libraries
Added: August 6, 2018
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