Emily Ozpinar
Also known as: Emily A. Wrona
Works (20)
Updated: August 21st, 2023 21:15
2022 journal article
Monitoring decellularization via absorbance spectroscopy during the derivation of extracellular matrix scaffolds
BIOMEDICAL MATERIALS, 17(1).
co-author countries:
United States of America 🇺🇸
author keywords: extracellular matrix; manufacturing; decellularization; monitoring; vocal fold
MeSH headings : Biocompatible Materials; Extracellular Matrix / chemistry; Hydrogels; Regenerative Medicine; Spectrum Analysis; Tissue Engineering / methods; Tissue Scaffolds
iopscience.iop.org (publisher PDF)
Sources: ORCID, Web Of Science
Added: November 4, 2021
2021 journal article
Dermal Extracellular Matrix-Derived Hydrogels as an In Vitro Substrate to Study Mast Cell Maturation
TISSUE ENGINEERING PART A, 27(15-16), 1008–1022.
co-author countries:
United States of America 🇺🇸
author keywords: extracellular matrix; mast cell; allergy; metabolism
MeSH headings : Animals; Cell Differentiation; Collagen; Extracellular Matrix; Humans; Hydrogels; Mast Cells; Swine
Sources: Web Of Science, ORCID
Added: December 11, 2020
2021 journal article
Mast Cell-Biomaterial Interactions and Tissue Repair
TISSUE ENGINEERING PART B-REVIEWS, 27(6), 590–603.
co-author countries:
United States of America 🇺🇸
author keywords: mast cells; biomaterials; inflammation; tissue repair; foreign body response; wound healing
MeSH headings : Biocompatible Materials; Cell Communication; Fibrosis; Humans; Mast Cells / pathology; Tissue Engineering
Sources: Web Of Science, ORCID
Added: March 8, 2021
2021 journal article
Transcriptome-targeted analysis of human peripheral blood-derived macrophages when cultured on biomaterial meshes
BIOMEDICAL MATERIALS, 16(2).
co-author countries:
United States of America 🇺🇸
author keywords: surgical meshes; macrophage polarization; biomaterials; targeted transcriptome; poly-4-hydroxybutyrate (P4HB); polypropylene
MeSH headings : Anti-Inflammatory Agents / chemistry; Biocompatible Materials / chemistry; Cell Culture Techniques; Cell Differentiation; Cell Separation; Cells, Cultured; Flow Cytometry; Gene Expression Profiling; Humans; Hydroxybutyrates; Immunity, Innate; In Vitro Techniques; Inflammation; Macrophages / drug effects; Macrophages / metabolism; Materials Testing; Monocytes / cytology; Phenotype; Polypropylenes / chemistry; Prostheses and Implants; RNA / metabolism; Surgical Mesh; Tissue Scaffolds; Transcriptome; Treatment Outcome; Up-Regulation; Wound Healing
Sources: ORCID, Web Of Science
Added: January 16, 2021
2020 journal article
An off-the-shelf artificial cardiac patch improves cardiac repair after myocardial infarction in rats and pigs
Science Translational Medicine, 12(538).
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Cell- and Tissue-Based Therapy; Extracellular Matrix; Heart; Myocardial Infarction / therapy; Myocardium; Rats; Swine
Source: ORCID
Added: April 9, 2020
2020 journal article
Dermal Extracellular Matrix-Derived Hydrogels as an In Vitro Substrate to Study Mast Cell Maturation
Tissue Engineering Part A.
MeSH headings : Animals; Cell Differentiation; Collagen; Extracellular Matrix; Humans; Hydrogels; Mast Cells; Swine
Source: ORCID
Added: October 4, 2020
2020 journal article
Fast Automated Approach for the Derivation of Acellular Extracellular Matrix Scaffolds from Porcine Soft Tissues
ACS Biomaterials Science & Engineering, 6(7), 4200–4213.
co-author countries:
United States of America 🇺🇸
author keywords: automation; decellularization; extracellular matrix; hydrogel; biomaterial; biofabrication
MeSH headings : Animals; Biocompatible Materials; Bioreactors; Extracellular Matrix; Hydrogels; Swine; Tissue Scaffolds
Source: ORCID
Added: June 16, 2020
2020 journal article
Mast Cell-Biomaterial Interactions and Tissue Repair
Tissue Engineering Part B: Reviews.
Source: ORCID
Added: November 11, 2020
2020 journal article
Porcine Vocal Fold Lamina Propria-Derived Biomaterials Modulate TGF-β1-Mediated Fibroblast Activation in Vitro
ACS Biomaterials Science & Engineering, 6(3), 1690–1703.
co-author countries:
United States of America 🇺🇸
author keywords: extracellular matrix; hydrogels; vocal fold lamina propria; MBVs; fibrosis
MeSH headings : Animals; Biocompatible Materials / pharmacology; Fibroblasts; Mucous Membrane; Swine; Transforming Growth Factor beta1; Vocal Cords
Source: ORCID
Added: February 13, 2020
2019 journal article
Effects of polarized macrophages on the in vitro gene expression after Co-Culture of human pluripotent stem cell-derived cardiomyocytes
Journal of Immunology and Regenerative Medicine.
Source: ORCID
Added: September 10, 2019
2018 journal article
Mesenchymal Stem Cell/Red Blood Cell-Inspired Nanoparticle Therapy in Mice with Carbon Tetrachloride-Induced Acute Liver Failure
ACS Nano, 12(7), 6536–6544.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: mesenchymal stem cells; red blood cells; biomimetic; nanoparticles; membrane cloaking; liver failure
MeSH headings : Animals; Apoptosis; Biomimetic Materials / chemistry; Biomimetic Materials / therapeutic use; Carbon Tetrachloride; Cell Line; Cell Proliferation; Disease Models, Animal; Erythrocyte Membrane / chemistry; Humans; Liver Failure, Acute / chemically induced; Liver Failure, Acute / pathology; Liver Failure, Acute / physiopathology; Liver Failure, Acute / therapy; Liver Regeneration; Male; Mesenchymal Stem Cells / chemistry; Mice; Mice, Inbred C57BL; Nanoparticles / chemistry; Nanoparticles / therapeutic use
Sources: ORCID, Crossref
Added: September 10, 2019
2018 review
Potential Synergistic Effects of Stem Cells and Extracellular Matrix Scaffolds
[Review of ]. ACS BIOMATERIALS SCIENCE & ENGINEERING, 4(4), 1208–1222.
co-author countries:
United States of America 🇺🇸
Contributors: L. Gaffney n, E. Wrona n & D. Freytes n
author keywords: extracellular matrix (ECM); stem cells; pluripotent stem cells (PSCs); wound healing; macrophage polarization
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
BMP protein-mediated crosstalk between inflammatory cells and human pluripotent stem cell-derived cardiomyocytes
Journal of Tissue Engineering and Regenerative Medicine, 11(5), 1466–1478.
co-author countries:
United States of America 🇺🇸
Contributors: I. Pallotta*, B. Sun*, E. Wrona* & D. Freytes*
author keywords: cardiomyocytes; macrophages; inflammation; BMP; migration; tissue engineering; regenerative medicine
MeSH headings : Bone Morphogenetic Protein 4 / metabolism; Cell Communication; Humans; Inflammation / metabolism; Inflammation / pathology; Macrophages / metabolism; Macrophages / pathology; Myocytes, Cardiac / metabolism; Myocytes, Cardiac / pathology; Pluripotent Stem Cells / metabolism; Pluripotent Stem Cells / pathology; Smad Proteins / metabolism
Sources: ORCID, Crossref
Added: September 10, 2019
2017 journal article
Macrophages' role in tissue disease and regeneration
Macrophages: Origin, Functions and Biointervention, 62, 245–271.
Source: NC State University Libraries
Added: August 6, 2018
2017 chapter
Macrophages’ role in tissue disease and regeneration
In Results and Problems in Cell Differentiation (Vol. 62, pp. 245–271).
co-author countries:
United States of America 🇺🇸
Contributors: L. Gaffney n, P. Warren n, E. Wrona n, M. Fisher n & D. Freytes n
MeSH headings : Animals; Humans; Inflammation / immunology; Macrophages / immunology; Regeneration / immunology; Regenerative Medicine; Tissue Engineering; Wound Healing / immunology
Source: ORCID
Added: September 10, 2019
2016 journal article
Differential gene expression in human, murine, and cell line-derived macrophages upon polarization
Experimental Cell Research, 347(1), 1–13.
co-author countries:
United States of America 🇺🇸
Contributors: K. Spiller *, E. Wrona*, S. Romero-Torres, I. Pallotta*, P. Graney *, C. Witherel*, L. Panicker*, R. Feldman *
author keywords: Classically activated; Alternatively activated macrophages; Wound healing; In vitro characterization; Angiogenesis; Tissue engineering; Induced pluripotent stem cells; Biomaterials
MeSH headings : Animals; Biocompatible Materials / pharmacology; Cell Differentiation / drug effects; Cell Line; Cell Polarity / drug effects; Cell Polarity / genetics; Discriminant Analysis; Gene Expression Profiling; Gene Expression Regulation / drug effects; Humans; Interferon-gamma / pharmacology; Least-Squares Analysis; Lipopolysaccharides / pharmacology; Macrophages / cytology; Macrophages / drug effects; Macrophages / metabolism; Mice, Inbred BALB C; Phenotype
Sources: ORCID, Crossref
Added: September 10, 2019
2016 review
Extracellular Matrix for Vocal Fold Lamina Propria Replacement: A Review
[Review of ]. TISSUE ENGINEERING PART B-REVIEWS, 22(6), 421–429.
co-author countries:
United States of America 🇺🇸
Contributors: E. Wrona n, R. Peng*, M. Amin*, R. Branski * & D. Freytes n
author keywords: voice; vocal fold; extracellular matrix; scaffold
MeSH headings : Extracellular Matrix; Humans; Mucous Membrane; Regenerative Medicine; Tissue Engineering; Vocal Cords
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Derivation and characterization of porcine vocal fold extracellular matrix scaffold
The Laryngoscope, 126(4), 928–935.
co-author countries:
United States of America 🇺🇸
Contributors: E. Wrona*, R. Peng*, H. Born *, M. Amin*, R. Branski * & D. Freytes*
author keywords: Vocal fold; extracellular matrix; mesenchymal stem cells; scaffold
MeSH headings : Animals; Cells, Cultured; DNA / analysis; Deoxycholic Acid; Extracellular Matrix / physiology; Gene Expression; Mesenchymal Stem Cells / cytology; Peracetic Acid; Swine; Tissue Engineering / methods; Tissue Scaffolds; Vocal Cords / cytology
Sources: ORCID, Crossref
Added: September 10, 2019
2015 chapter
Role of mesenchymal stem cells, macrophages, and biomaterials during myocardial repair
In Biomaterials in Regenerative Medicine and the Immune System (pp. 1–15).
co-author countries:
United States of America 🇺🇸
Contributors: I. Pallotta*, E. Wrona*, B. Sun* & D. Freytes *
Source: ORCID
Added: September 10, 2019
2014 book
Natural cardiac extracellular matrix hydrogels for cultivation of human stem cell-derived cardiomyocytes
In Methods in Molecular Biology (Vol. 1181, pp. 69–81).
Contributors: D. Freytes *, . J.D. O'Neill, Y. Duan-Arnold*, E. Wrona* & G. Vunjak-Novakovic *
MeSH headings : Animals; Cell Count; Cell Culture Techniques / methods; Extracellular Matrix / chemistry; Flow Cytometry; Humans; Hydrogels / chemistry; Myocytes, Cardiac / cytology; Myocytes, Cardiac / metabolism; Staining and Labeling; Stem Cells / cytology; Tissue Engineering; Troponin T / metabolism
Source: ORCID
Added: September 10, 2019
Employment
Updated: July 5th, 2023 13:59
Booz Allen Hamilton VA, VA, US
Lead Scientist
Education
Updated: November 13th, 2019 14:26
North Carolina State University Raleigh, NC, US
PhD
Joint Department of Biomedical Engineering
University of Virginia Charlottesville, VA, US
BS
Biology
University of North Carolina at Chapel Hill Chapel Hill, NC, US
PhD
Joint Department of Biomedical Engineering
Funding History
Funding history based on the linked ORCID record. Updated: November 13th, 2019 14:29
award
Predoctoral Fellowship
American Heart Association
