Works (543)

Updated: December 16th, 2024 05:03

2024 journal article

<i>Bartonella</i> species bacteremia in association with adult psychosis

FRONTIERS IN PSYCHIATRY, 15.

By: S. Delaney*, C. Robveille n, R. Maggi n, E. Lashnits*, E. Kingston n, C. Liedig n, L. Murray*, B. Fallon*, E. Breitschwerdt n

author keywords: Bartonella; infection; psychosis; serology; polymerase chain reaction; neurologic diseases
Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 1, 2024

2024 journal article

<i>Bartonella</i> spp. in Phlebotominae Sand Flies, Brazil

EMERGING INFECTIOUS DISEASES, 30(10), 2099–2107.

By: D. Lee, P. Shimabukuro, A. Brilhante, P. Arantes, G. Sanches, E. Franco, R. Machado, R. Maggi*, E. Breitschwerdt*, M. Andre

Sources: Web Of Science, NC State University Libraries
Added: December 9, 2024

2024 journal article

<i>Bartonella</i> spp. infection in people with Mild Cognitive Impairment: A pilot study

PLOS ONE, 19(8).

By: V. Guirguis*, F. Pupillo*, S. Rodrigues*, N. Walker*, H. Roth*, C. Liedig n, R. Maggi n, E. Breitschwerdt*, F. Frohlich*

UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 16, 2024

2024 journal article

A case of mistaken identity: a systematic review, meta-analysis, and reinvestigation of hemotropic <i>Mycoplasma</i> spp. infection in <i>Ctenocephalides felis</i> (cat flea)

PARASITES & VECTORS, 17(1).

By: C. Moore n, E. Lashnits*, M. Lappin*, J. Hawley* & E. Breitschwerdt n

author keywords: Ctenocephalides felis; Cat flea; Hemotropic mycoplasma; Vector-borne; Flea-borne pathogen; Mycoplasma haemofelis; Candidatus Mycoplasma turicensis; Mycoplasma haemominutum
Sources: Web Of Science, NC State University Libraries
Added: May 20, 2024

2024 article

A case of mistaken identity: a systematic review, meta-analysis, and reinvestigation of hemotropic Mycoplasma spp. infection in Ctenocephalides felis (cat flea) (vol 17, 209, 2024)

Moore, C. O., Lashnits, E., Lappin, M., Hawley, J., & Breitschwerdt, E. B. (2024, October 30). PARASITES & VECTORS, Vol. 17.

By: C. Moore n, E. Lashnits*, M. Lappin*, J. Hawley* & E. Breitschwerdt n

Sources: Web Of Science, NC State University Libraries
Added: November 12, 2024

2024 journal article

A comparison of <i>Bartonella henselae</i> infection in immunocompetent and immunocompromised mice

PLOS ONE, 19(2).

By: R. Bullard*, M. Cheslock*, S. Gadila*, R. Maggi n, E. Breitschwerdt n, A. Saied*, M. Embers*

TL;DR: Data indicate that SCID/Beige mice can provide a model to study Bartonella infection, therapeutics, and vector dynamics in the future. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 11, 2024

2024 article

Antibodies to <i>Borrelia burgdorferi</i> and <i>Bartonella</i> species in serum and synovial fluid from people with rheumatic diseases

Kim, L., Lashnits, E., Breitschwerdt, E. B., Elam, A., Grade, N., Miller, J., & Shikhman, A. R. (2024, March 14). MICROBIOLOGY SPECTRUM, Vol. 3.

By: L. Kim*, E. Lashnits*, E. Breitschwerdt n, A. Elam*, N. Grade*, J. Miller*, A. Shikhman

author keywords: antibodies; Bartonella; Borrelia burgdorferi; immunoserology; Lyme; serodiagnosis; rheumatology
Sources: Web Of Science, NC State University Libraries
Added: April 8, 2024

2024 journal article

Assessment of the effect of long-term serum storage for retrospective serologic diagnosis of canine monocytic ehrlichiosis (<i> Ehrlichia</i> canis )

COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES, 108.

By: M. Karagkouni*, K. Spilioti, E. Meletis*, P. Kostoulas*, C. Koutinas*, K. Theodorou, E. Breitschwerdt n, M. Mylonakis*

author keywords: Diagnosis; Dog; Ehrlichia canis; Serology; Storage time
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 28, 2024

2024 journal article

Development of Multiplex Assays for the Identification of Zoonotic Babesia Species

Pathogens.

By: A. Calchi, C. Moore, L. Bartone, E. Kingston, M. André, E. Breitschwerdt, R. Maggi

Source: ORCID
Added: December 11, 2024

2024 article

Diagnostic challenge in veterinary pathology: Tri-cavitary effusion in a cat with systemic pyogranulomatous inflammation

Fingerhood, S., Neupane, P., Breitschwerdt, E. B., & Choi, E. A. (2024, January 21). VETERINARY PATHOLOGY, Vol. 1.

By: S. Fingerhood*, P. Neupane n, E. Breitschwerdt n & E. Choi*

Sources: Web Of Science, NC State University Libraries
Added: January 29, 2024

2024 journal article

Dilated cardiomyopathy of possible dietary origin in a cat

JOURNAL OF VETERINARY CARDIOLOGY, 51, 172–178.

By: B. Duperry*, K. Lopez*, J. Rush*, B. Berridge, R. Mitchell*, E. Breitschwerdt n, L. Freeman*

author keywords: Nutrition; Heart failure; Pulses; Feline; Electron microscopy
TL;DR: The relative roles of diet change, cardiac medications, and a dedicated owner are unclear, but this cat's relatively long survival time is similar to that seen after diet change in dogs and cats with DCM eating high-pulse diets. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 12, 2024

2024 article

Evaluation of the Veterinary IDEXX SNAP 4Dx Plus Test for the Diagnosis of Lyme Disease in Humans

Lee, G., Pretsch, P., Ursery, L., Giandomenico, D., Abernathy, H. A., Evans, L., … Boyce, R. M. (2024, June 19). VECTOR-BORNE AND ZOONOTIC DISEASES, Vol. 6.

By: G. Lee*, P. Pretsch*, L. Ursery*, D. Giandomenico*, H. Abernathy*, L. Evans*, B. Qurollo n, E. Breitschwerdt n, R. Boyce*

author keywords: Lyme disease; point-of-care; serology; diagnosis
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 1, 2024

2024 journal article

Human <i>Babesia odocoilei</i> and <i>Bartonella</i> spp. co-infections in the Americas

PARASITES & VECTORS, 17(1).

By: R. Maggi n, A. Calchi*, C. Moore n, E. Kingston n & E. Breitschwerdt n

author keywords: Bartonella; Babesiosis; Babesia odocoilei; Zoonotic diseases; Co-infection; Fatigue; Neurology
Sources: ORCID, Web Of Science, NC State University Libraries
Added: July 15, 2024

2024 journal article

Sequence typing of <i>Bartonella henselae</i> in small Indian mongooses (<i>Urva auropunctata</i>)

SCIENTIFIC REPORTS, 14(1).

By: A. Muller*, R. Maggi n, P. Sepulveda-Garcia*, A. Mau*, C. Sauve*, A. Conan, I. Branford*, P. Bittencourt*, E. Breitschwerdt n

Sources: Web Of Science, NC State University Libraries
Added: September 9, 2024

2024 journal article

The role of vector-borne pathogens and cardiac Striatin genotype on survival in boxer dogs with arrhythmogenic right ventricular cardiomyopathy

JOURNAL OF VETERINARY CARDIOLOGY, 56, 84–96.

By: B. Ditzler, E. Lashnits*, K. Meurs*, R. Maggi*, M. Yata, P. Neupane*, E. Breitschwerdt*

author keywords: Canine; Heart; Infection; Gene; Bartonella
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 22, 2024

2024 review

Vector biology of the cat fl ea<i> Ctenocephalides felis</i>

[Review of ]. TRENDS IN PARASITOLOGY, 40(4), 324–337.

By: C. Moore n, M. Andre*, J. Slapeta* & E. Breitschwerdt n

TL;DR: Fundamental aspects of C. felis as a vector are reviewed with an emphasis on key techniques and research avenues employed in other vector species, improving the accuracy of vector and pathogen modeling to improve infection/infestation risk assessment and diagnostic recommendations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 8, 2024

2023 article

A second-generation, point-of-care immunoassay provided improved detection of Anaplasma and Ehrlichia antibodies in PCR-positive dogs naturally infected with Anaplasma or Ehrlichia species

Richardson, S. S., Mainville, C. A., Arguello-Marin, A., Whalley, D., Burton, W., Breitschwerdt, E. B., & Qurollo, B. A. (2023, May 9). JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, Vol. 5.

By: S. Richardson n, C. Mainville*, A. Arguello-Marin*, D. Whalley*, W. Burton*, E. Breitschwerdt n, B. Qurollo n

author keywords: Anaplasma; dogs; Ehrlichia; immunoassay; point-of-care; serology; tick-borne pathogens
TL;DR: The second-generation SNAP 4Dx Plus test offered improved serologic detection of Anaplasma and Ehrlichia in naturally infected dogs, and case management decisions might have been different with an immediate anaplasmosis diagnosis, including earlier doxycycline therapy and less hospitalization. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: May 30, 2023

2023 article

Blood Supplementation Enhances Bartonella henselae Growth and Molecular Detection of Bacterial DNA in Liquid Culture

Liedig, C., Neupane, P., Lashnits, E., Breitschwerdt, E. B., & Maggi, R. G. (2023, May 25). (H. H. Mostafa, Ed.). MICROBIOLOGY SPECTRUM, Vol. 5.

By: C. Liedig n, P. Neupane*, E. Lashnits*, E. Breitschwerdt n & R. Maggi n

Ed(s): H. Mostafa

author keywords: BAPGM; Bartonella culture; Bartonella henselae; bartonellosis; blood supplementation; diagnostics
MeSH headings : Humans; Animals; Horses / genetics; Dogs; Sheep; Bartonella henselae / genetics; DNA, Bacterial / genetics; DNA, Bacterial / analysis; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella / genetics; Dietary Supplements; Mammals
TL;DR: The addition of sheep blood to liquid culture media increased the Bartonella henselae DNA concentration compared to controls, additionally improving PCR direct detection sensitivity. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: May 26, 2023

2023 journal article

Case report: Substantial improvement of autism spectrum disorder in a child with learning disabilities in conjunction with treatment for poly-microbial vector borne infections

FRONTIERS IN PSYCHIATRY, 14.

By: A. Offutt & E. Breitschwerdt n

author keywords: tics; infections; Bartonella; Lyme; PANS; OCD; autism; ADHD
TL;DR: Targeted antimicrobial treatment resulted in substantial improvement in cognitive and neurobehavioral symptoms in a boy diagnosed with autism spectrum disorder. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 18, 2023

2023 journal article

Eosinophilic pericardial effusion and pericarditis in a cat

JOURNAL OF FELINE MEDICINE AND SURGERY OPEN REPORTS, 9(2).

By: M. Wheatley n, J. Shamoun n, R. Maggi n, E. Breitschwerdt n, S. Sommer*, J. Cullen n, D. Stowe n

author keywords: Apicomplexan; Bartonella; eosinophilic effusion; mesothelial cells; pericardial effusion; pericarditis
TL;DR: This case offers several unique entities and illustrates the well-known marked atypia that may occur in reactive and hyperplastic mesothelial cells, particularly of infrequently sampled and cytologically described feline pericardial effusion, supporting a cautious interpretation of this cytology finding. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: December 18, 2023

2023 article

Establishment of a consensus protocol to explore the brain pathobiome in patients with mild cognitive impairment and Alzheimer's disease Research outline and call for collaboration

Lathe, R., Schultek, N. M., Balin, B. J., Ehrlich, G. D., Auber, L. A., Perry, G., … Tanzi, R. E. (2023, June 7). ALZHEIMERS & DEMENTIA, Vol. 6.

By: R. Lathe*, N. Schultek, B. Balin*, G. Ehrlich*, L. Auber, G. Perry*, E. Breitschwerdt n, D. Corry* ...

author keywords: Alzheimer's disease; antimicrobial; antiviral; bioinformatics; blood; cerebrospinal fluid; collaboration; dementia; diagnosis; methodology; microbiome; mild cognitive impairment; olfactory neuroepithelium; pathobiome; polymerase chain reaction; protocol; sequencing
TL;DR: The Alzheimer's Pathobiome Initiative aims to perform comparative molecular analyses of microbes in post mortem brains versus cerebrospinal fluid, blood, olfactory neuroepithelium, oral/nasopharyngeal tissue, bronchoalveolar, urinary, and gut/stool samples to provide a roadmap for detecting infectious agents in patients with mild cognitive impairment or AD. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: July 3, 2023

2023 journal article

Feeding on a Bartonella henselae Infected Host Triggers Temporary Changes in the Ctenocephalides felis Microbiome

PATHOGENS, 12(3).

By: C. Moore n, E. Lashnits n, P. Neupane n, B. Herrin*, M. Lappin*, M. Andre*, E. Breitschwerdt n

author keywords: Bartonella henselae; Ctenocephalides felis; flea; microbiome; wolbachia; vector microbiome
TL;DR: Using Next Generation Sequencing (NGS) on the Illumina platform, an increase in microbial diversity in C. felis microbiome when fed on B. henselae-infected cats is documented, which may be related to the mammalian, flea, or endosymbiont response. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 23, 2023

2023 article

Risk Factors for Bartonella Seroreactivity Among Veterinary Workers in the Pacific Northwest

Thiel, N., Baker, M., Lipton, B., Fuller, L., Breitschwerdt, E. B., & Rabinowitz, P. (2023, June 15). VECTOR-BORNE AND ZOONOTIC DISEASES, Vol. 6.

By: N. Thiel*, M. Baker*, B. Lipton*, L. Fuller, E. Breitschwerdt n & P. Rabinowitz*

author keywords: Bartonella henselae; Bartonella vinsonii; Bartonella koehlerae; risk matrix; zoonotic disease epidemiology; veterinarian occupational health
TL;DR: No significant predictors of seroreactivity were found, although the relationship between high-risk status and increased serore activity for some Bartonella species approached significance. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 26, 2023

2023 journal article

The association of host and vector characteristics with Ctenocephalides felis pathogen and endosymbiont infection

FRONTIERS IN MICROBIOLOGY, 14.

By: C. Moore n, E. Breitschwerdt n, L. Kim*, Y. Li*, K. Ferris n, R. Maggi n, E. Lashnits*

author keywords: Bartonella; flea; Wolbachia; vector phylogenetics; flea associated Rickettsia; host-vector agreement; cat flea
TL;DR: There was poor flea and host agreement for Bartonella spp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 4, 2023

2023 journal article

Viability and Desiccation Resistance of Bartonella henselae in Biological and Non-Biological Fluids: Evidence for Pathogen Environmental Stability

PATHOGENS, 12(7).

By: J. Bush n, R. Maggi n & E. Breitschwerdt n

author keywords: Bartonella; vector-borne; zoonotic; intracellular; alphaproteobacteria; desiccation; environment
TL;DR: The viability and stability of Bartonella within biological and non-biological fluids in the environment may represent a previously unrecognized source of infection for animals and human beings. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: July 20, 2023

2022 article

A bottom-up proteomics workflow for a system containing multiple organisms

Bai, H., Collins, L. B. B., Andre, M. R., Breitschwerdt, E. B. B., & Williams, T. I. (2023, January 3). RAPID COMMUNICATIONS IN MASS SPECTROMETRY, Vol. 1.

By: H. Bai n, L. Collins n, M. Andre n, E. Breitschwerdt n & T. Williams n

Contributors: H. Bai n, L. Collins n, M. André n, E. Breitschwerdt n & T. Williams n

TL;DR: A bottom-up proteomics workflow was developed to study a system containing multiple organisms to promote a thorough understanding of how each interacts with the others and can be readily applied to other label-free proteomics work involving multiple proteomes from taxonomically distinct organisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 25, 2022

2022 journal article

An Improved Point-of-Care ELISA for the Diagnosis of Anaplasmosis and Ehrlichiosis During the Acute Phase of Tick-Borne Infections in Dogs

TOPICS IN COMPANION ANIMAL MEDICINE, 51.

By: M. Beall*, C. Mainville*, A. Arguello-Marin*, G. Clark*, C. Lemieux*, J. Saucier*, B. Thatcher*, E. Breitschwerdt n ...

author keywords: Antibody; PCR; Serology; Infectious canine cyclic thrombocytopenia
MeSH headings : Dogs; Animals; Anaplasmosis; Point-of-Care Systems; Dirofilaria immitis; Dirofilariasis / diagnosis; Lyme Disease / diagnosis; Lyme Disease / veterinary; Antibodies, Bacterial; Dog Diseases; Ehrlichiosis / diagnosis; Ehrlichiosis / veterinary; Tick-Borne Diseases / veterinary; Ehrlichia; Enzyme-Linked Immunosorbent Assay / veterinary; Enzyme-Linked Immunosorbent Assay / methods
TL;DR: It is demonstrated that the second-generation POC ELISA had an improved ability to detect serologic responses during the acute phase of A. phagocytophilum, A. platys, and E. canis experimental infections. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: February 20, 2023

2022 journal article

Bartonella henselae Recombinant Pap31 for the Diagnosis of Canine and Human Bartonelloses

PATHOGENS, 11(2).

By: P. Neupane n, R. Maggi n, M. Basnet*, E. Lashnits*, G. Andrews* & E. Breitschwerdt n

author keywords: antigen; Bartonella henselae; serology; diagnosis; ELISA; Western blot; heme binding proteins
TL;DR: It is indicated that recombinant Pap31 and the selected fragments may not be appropriate diagnostic targets in detecting anti-Bartonella antibodies in Bartonella-infected dogs and humans. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 2, 2022

2022 journal article

Cat scratch disease: What to do with the cat?

American Journal of Ophthalmology Case Reports.

By: A. Smolar*, E. Breitschwerdt n, P. Phillips*, N. Newman* & V. Biousse*

TL;DR: When addressing the concerns of CSD patients in clinical practice, ophthalmologists should be aware of the strategies for minimizing Bartonella transmission risk, and cognizant of the One Health approach for managing zoonoses. (via Semantic Scholar)
Source: ORCID
Added: September 10, 2022

2022 article

FtlA and FtlB Are Candidates for Inclusion in a Next-Generation Multiantigen Subunit Vaccine for Lyme Disease

Camire, A. C., Nathaniel S. O'Bier, Patel, D. T., Cramer, N. A., Straubinger, R. K., Breitschwerdt, E. B., … Marconi, R. T. (2022, September 14). INFECTION AND IMMUNITY, Vol. 9.

By: A. Camire*, . Nathaniel S. O'Bier*, D. Patel*, N. Cramer*, R. Straubinger*, E. Breitschwerdt n, R. Funk*, R. Marconi*

author keywords: Borreliella; Borrelia; BBK01; BBG01; Ftl; Lyme disease vaccine; protein family 12; FtlA; Ixodes; Lyme vaccine; PF12; canine Lyme disease; chimeritope
MeSH headings : Animals; Dogs; Antibodies, Bacterial; Antigens, Bacterial; Bacterial Outer Membrane Proteins / genetics; Borrelia burgdorferi; Epitopes; Horses; Immune Sera; Ixodes / microbiology; Lipoproteins / genetics; Lyme Disease / microbiology; Vaccines, Combined; Vaccines, Subunit / genetics
TL;DR: It is suggested that FtlA and FtlB are potential candidates for inclusion in a multivalent vaccine for LD, and epitope localization revealed that the bactericidal epitopes reside within the N-terminal domain of the Ftl proteins. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: September 26, 2022

2022 journal article

Prospective serological and molecular cross-sectional study focusing on Bartonella and other blood-borne organisms in cats from Catalonia (Spain)

PARASITES & VECTORS, 15(1).

By: A. Alvarez-Fernandez*, R. Maggi n, G. Eduard Martin-Valls, M. Baxarias*, E. Bealmear Breitschwerdt & L. Solano-Gallego*

author keywords: Bartonellosis; Hemotropic Mycoplasma; Mycoplasma wenyonii; Ehrlichia; Anaplasma; Piroplasma; Co-infection; Cats; Spain
MeSH headings : Animals; Antibodies, Bacterial / blood; Antigens, Bacterial / immunology; Bartonella / genetics; Bartonella / immunology; Bartonella Infections / blood; Bartonella Infections / epidemiology; Bartonella Infections / transmission; Bartonella Infections / veterinary; Cat Diseases / blood; Cat Diseases / epidemiology; Cat Diseases / microbiology; Cat Diseases / transmission; Cats; Cross-Sectional Studies; DNA, Bacterial / blood; DNA, Bacterial / isolation & purification; DNA, Ribosomal Spacer / chemistry; Female; Fluorescent Antibody Technique / veterinary; Male; Polymerase Chain Reaction / veterinary; Prevalence; Prospective Studies; RNA, Ribosomal, 16S / genetics; RNA, Ribosomal, 23S / genetics; Real-Time Polymerase Chain Reaction / veterinary; Seroepidemiologic Studies; Spain / epidemiology
TL;DR: This study is the first to document M. wenyonii is infection in cats, and substantial to almost perfect serological agreement was found between the three Bartonella species. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 18, 2022

2022 journal article

Rickettsia typhi infection in a clinically-ill dog from Houston, Texas

VETERINARY PARASITOLOGY- REGIONAL STUDIES AND REPORTS, 35.

By: N. Juhasz n, J. Wilson n, K. Haney n, M. Clark*, A. Davenport*, E. Breitschwerdt n, B. Qurollo n

author keywords: Dog; Rickettsia typhi; Murine typhus; North America
MeSH headings : Animals; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dogs; Doxycycline / therapeutic use; Polymerase Chain Reaction / veterinary; Rickettsia typhi; Texas; Typhus, Endemic Flea-Borne / diagnosis; Typhus, Endemic Flea-Borne / drug therapy; Typhus, Endemic Flea-Borne / veterinary
TL;DR: In 2020, Rickettsia typhi was diagnosed in a dog from Houston, Texas, USA based upon R. typhi IFA seroreactivity in both acute and convalescent sera, and PCR with DNA sequencing of 4 different gene regions, all of which were 100% identical to R. Typhi. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 11, 2022

2022 journal article

Using Proteomic Approaches to Unravel the Response of Ctenocephalides felis felis to Blood Feeding and Infection With Bartonella henselae

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 12.

By: M. Andre n, P. Neupane n, M. Lappin*, B. Herrin*, V. Smith*, T. Williams n, L. Collins n, H. Bai n ...

Contributors: M. André n, P. Neupane n, M. Lappin*, B. Herrin*, V. Smith*, T. Williams n, L. Collins n, H. Bai n ...

author keywords: bartonellosis; cat flea; cat scratch disease; flea-pathogen interface; proteome
MeSH headings : Animals; Bartonella henselae / genetics; Cat Diseases; Cats; Ctenocephalides; Felis; Proteomics; Siphonaptera
TL;DR: Flea-differentially abundant proteins (FDAP) are investigated in unfed fleas, fleas fed on uninfected cats, and flea fed on B. henselae-infected cats to help understand the complex interactions between cat fleas and B. Henselae over an infection time course, thus helping understand the dual effect of vaccine targeting both flea fitness and pathogen competence. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: January 29, 2022

2022 article

Vector-borne disease and its relationship to hematologic abnormalities and microalbuminuria in retired racing and show-bred greyhounds

Kidd, L., Hamilton, H., Stine, L., Qurollo, B., & Breitschwerdt, E. B. (2022, July 11). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 7.

By: L. Kidd*, H. Hamilton*, L. Stine*, B. Qurollo n & E. Breitschwerdt n

author keywords: Babesia; Bartonella; Ehrlichia thrombocytopenia; hemotropic Mycoplasma; leukopenia; proteinuria
MeSH headings : Anaplasma; Animals; Babesia; Bartonella; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Ehrlichia canis; Mycoplasma; Proteinuria / veterinary; Thrombocytopenia / epidemiology; Thrombocytopenia / veterinary; Vector Borne Diseases / veterinary
TL;DR: The prevalence of thrombocytopenia and B. vogeli exposure was lower than previously documented and larger studies investigating the health impact of multiple VBD organisms are warranted. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: July 26, 2022

2021 journal article

Bartonella henselae Antibodies in Serum and Oral Fluid Specimens from Cats

PATHOGENS, 10(3).

By: A. Alvarez-Fernandez*, M. Baxarias*, D. Prandi*, E. Breitschwerdt n & L. Solano-Gallego*

author keywords: bartonellosis; feline; serology; immunofluorescence antibody assay; oral fluid
TL;DR: B. henselae OF IFA antibody measurements were less sensitive compared to serum IFA measurements of ≥1:64, therefore, OF antibodies, detectable by IFA, is of limited utility for epidemiological or diagnostic testing in cats. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 12, 2021

2021 journal article

Bartonella henselae Detected in Malignant Melanoma, a Preliminary Study

PATHOGENS, 10(3).

By: M. Ericson*, E. Breitschwerdt n, P. Reicherter*, C. Maxwell*, R. Maggi n, R. Melvin*, A. Maluki*, J. Bradley n ...

author keywords: melanoma; A375 cells; Bartonella spp; Bartonella henselae; vector-borne pathogens; multi-immunostaining methods; confocal microscopy of thick sections; cancer microbiome; melanoma pathobiome
TL;DR: Findings from this small number of patients support the need for future investigations to determine the extent to which Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 11, 2021

2021 article

Bartonella spp. seroepidemiology and associations with clinicopathologic findings in dogs in the United States

Lashnits, E., Thatcher, B., Carruth, A., Mestek, A., Buch, J., Beall, M., … Breitschwerdt, E. B. (2021, November 17). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 11.

By: E. Lashnits n, B. Thatcher*, A. Carruth*, A. Mestek*, J. Buch*, M. Beall*, P. Neupane n, R. Chandrashekar*, E. Breitschwerdt n

author keywords: bartonellosis; canine; seroreactivity; vector-borne; zoonoses
MeSH headings : Animals; Bartonella; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Dog Diseases / epidemiology; Dogs; Retrospective Studies; Seroepidemiologic Studies; United States / epidemiology
TL;DR: Demographic and geographic findings for Bartonella spp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 18, 2021

2021 journal article

Comparison of Serological and Molecular Assays for Bartonella Species in Dogs with Hemangiosarcoma

PATHOGENS, 10(7).

By: E. Lashnits n, P. Neupane n, J. Bradley n, T. Richardson n, R. Maggi n & E. Breitschwerdt n

author keywords: diagnostic testing; ddPCR; PCR; serology; sensitivity; specificity; tissue biopsy; latent class analysis
TL;DR: Data indicate that Bartonella spp. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 24, 2021

2021 journal article

Demographics and travel history of imported and autochthonous cases of leishmaniosis in dogs in the United States and Canada, 2006 to 2019

JOURNAL OF VETERINARY INTERNAL MEDICINE, 35(2), 954–964.

By: T. Gin n, E. Lashnits n, J. Wilson n, E. Breitschwerdt n & B. Qurollo n

author keywords: dog; leishmania; lutzomyia
MeSH headings : Animals; Canada / epidemiology; Demography; Dog Diseases / epidemiology; Dogs; Leishmania infantum; Retrospective Studies; Seroepidemiologic Studies; United States / epidemiology
TL;DR: Leishmania surveillance should be considered for dogs that return from L. infantum‐endemic regions to monitor emergence of this zoonotic disease in the US and Canada, and several nonfoxhound breeds had no travel history. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 27, 2021

2021 journal article

Development of a Multiplex Droplet Digital PCR Assay for the Detection of Babesia, Bartonella, and Borrelia Species

PATHOGENS, 10(11).

By: R. Maggi n, E. Breitschwerdt n, B. Qurollo n & J. Miller*

author keywords: Babesia; Bartonella; Borrelia; Cytauxzoon; Piroplasma; Theileria; clinical diagnostics; molecular detection; digital droplet PCR; digital PCR
TL;DR: The ddPCR assay facilitated the simultaneous detection of co-infections with two and three vector-borne pathogens comprising four different genera (Babesia, Bartonella, Borrelia, and Theileria) from clinical and other sample sources. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 12, 2021

2021 journal article

Exposure of Domestic Cats to Three Zoonotic Bartonella Species in the United States

PATHOGENS, 10(3).

By: L. Osikowicz*, K. Horiuchi*, I. Goodrich*, E. Breitschwerdt n, B. Chomel*, B. Biggerstaff*, M. Kosoy

author keywords: domestic cats; cat scratch disease; Bartonella henselae; Bartonella clarridgeiae; Bartonella koehlerae; serosurvey; IFA; vector-borne pathogens
TL;DR: Cat-associated Bartonella species, which include B. henselae, B. koehlerae, and B. clarridgeiae, can cause mild to severe illness in humans, and seroreactivity against three species and two strain types associated with cats was evaluated across the U.S. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 17, 2021

2021 article

Haematological and biochemical abnormalities in hunting dogs infected with Acanthocheilonema reconditum, associated risk factors, and a European overview

Pacifico, L., Ferrari, N., Romeo, C., Buono, F., Varuzza, P., Sgroi, G., … Piantedosi, D. (2021, May 8). PARASITOLOGY RESEARCH, Vol. 5.

By: L. Pacifico*, N. Ferrari*, C. Romeo*, F. Buono*, P. Varuzza*, G. Sgroi*, B. Neola*, J. Buch* ...

author keywords: Filarial nematodes; Acanthocheilonema spp; CVBDs; Hunting dogs
MeSH headings : Acanthocheilonema / isolation & purification; Acanthocheilonema / pathogenicity; Acanthocheilonemiasis / blood; Acanthocheilonemiasis / epidemiology; Acanthocheilonemiasis / parasitology; Acanthocheilonemiasis / veterinary; Animals; Dog Diseases / blood; Dog Diseases / epidemiology; Dog Diseases / parasitology; Dogs; Hematologic Diseases / blood; Hematologic Diseases / epidemiology; Hematologic Diseases / parasitology; Hematologic Diseases / veterinary; Italy / epidemiology; Male; Microfilariae / isolation & purification; Microfilariae / pathogenicity; Prevalence; Risk Factors; Working Dogs / parasitology
TL;DR: The results showed that A. reconditum circulates within the hunting dog population of southern Italy, with seemingly low pathogenic potential. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 10, 2021

2021 journal article

Prevalence of Vector-Borne Pathogens in Reproductive and Non-Reproductive Tissue Samples from Free-Roaming Domestic Cats in the South Atlantic USA

PATHOGENS, 10(9).

By: C. Manvell n, K. Ferris n, R. Maggi n, E. Breitschwerdt n & E. Lashnits n

author keywords: Bartonella spp; hemotropic Mycoplasma spp; reproduction; cats; prevalence
TL;DR: Ear tip and reproductive tissues of FRCs from two locations in the South Atlantic United States for Anaplasma, Bartonella, Ehrlichia, hemotropic Mycoplasma, and Rickettsia species suggest that B. henselae preferentially infected cats’ reproductive tissue and reinforces the importance of investigating the potential for vertical transmission or induction of reproductive failure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 22, 2021

2021 review

Recent Progress in Lyme Disease and Remaining Challenges

[Review of ]. FRONTIERS IN MEDICINE, 8.

author keywords: Lyme disease; pathogenesis; diagnosis; treatment; prevention; field building; PTLD; vaccine
TL;DR: Progress over the past 5 years in the understanding of Lyme and tick-borne diseases in the United States is summarized and remaining challenges are highlighted. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: September 20, 2021

2021 journal article

Schizophrenia and Bartonella spp. Infection: A Pilot Case-Control Study

VECTOR-BORNE AND ZOONOTIC DISEASES, 21(6), 413–421.

By: E. Lashnits n, R. Maggi n, F. Jarskog*, J. Bradley n, E. Breitschwerdt n & F. Frohlich*

author keywords: vector-borne disease; infectious disease; cat; epidemiology; ddPCR; cat scratch disease
MeSH headings : Animals; Bartonella / genetics; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Case-Control Studies; Pilot Projects; Schizophrenia
TL;DR: Preliminary evidence in support of future investigations that should examine a potential contribution of Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: April 5, 2021

2021 journal article

Suspected Bartonella osteomyelitis in a dog

CLINICAL CASE REPORTS, 9(7).

By: F. Easley n, L. Taylor & E. Breitschwerdt n

author keywords: bone; infection; kidney; polydipsia and polyuria
TL;DR: Infection with Bartonella spp. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: July 22, 2021

2020 journal article

A retrospective study of vector‐borne disease prevalence in dogs with proteinuria: Southeastern United States

Journal of Veterinary Internal Medicine, 1(2), 742–753.

By: E. Purswell n, E. Lashnits n, E. Breitschwerdt n & S. Vaden n

author keywords: anaplasmosis; ehrlichiosis; flea; immune-mediated; rickettsioses; tick
MeSH headings : Animals; Cross-Sectional Studies; Dog Diseases / epidemiology; Dog Diseases / etiology; Dogs; Female; Male; Prevalence; Proteinuria / veterinary; Retrospective Studies; Risk Factors; Seasons; Southeastern United States / epidemiology; Vector Borne Diseases / epidemiology; Vector Borne Diseases / veterinary
TL;DR: Exposure to CVBD, particularly exposure to Rickettsia spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: January 9, 2020

2020 journal article

Bartonella Associated Cutaneous Lesions (BACL) in People with Neuropsychiatric Symptoms

Pathogens, 9(12), 1023.

By: E. Breitschwerdt n, J. Bradley n, R. Maggi n, E. Lashnits n & P. Reicherter*

author keywords: infection; bacteria; psychoses; transmission; stretch marks; bartonella; neuropsychiatric; cutaneous lesions; BACL
TL;DR: It is concluded that cutaneous lesions were common among people reporting neuropsychiatric symptoms and Bartonella spp. (via Semantic Scholar)
Source: ORCID
Added: December 5, 2020

2020 journal article

Bartonella rochalimae, a newly recognized pathogen in dogs

Journal of Veterinary Internal Medicine.

By: E. Ernst n, B. Qurollo n, C. Olech n & E. Breitschwerdt n

author keywords: emerging; endocarditis; infection; polymerase chain reaction; vector-borne
MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Endocarditis, Bacterial / veterinary; Female; Lameness, Animal; Male; Polymerase Chain Reaction / veterinary; Retrospective Studies; Seizures / veterinary; United States
TL;DR: A spectrum of clinical presentations accompanied by mild hematological abnormalities in B rochalimae‐infected dogs from the United States is documented to provide support for an association between B rochardimae and IE and provides documentation of dogs infected with B ro Chalimae with other clinical diagnoses. (via Semantic Scholar)
Source: ORCID
Added: May 17, 2020

2020 journal article

Bartonella spp. Prevalence (Serology, Culture, and PCR) in Sanitary Workers in La Rioja Spain

Pathogens, 9(3), 189.

author keywords: Bartonella Alpha-Proteobacteria Growth Medium (BAPGM); B. henselae; B. quintana; B. vinsonii subsp. berkhoffii; B. koehlerae; sanitary workers
TL;DR: The results suggest that exposure to and non-clinical infection with Bartonella spp. (via Semantic Scholar)
Source: ORCID
Added: March 7, 2020

2020 journal article

Development and validation of a droplet digital PCR assay for the detection and quantification of Bartonella species within human clinical samples

JOURNAL OF MICROBIOLOGICAL METHODS, 176.

By: R. Maggi n, T. Richardson*, E. Breitschwerdt n & J. Miller*

author keywords: Bartonella; Clinical diagnostics; Molecular detection; Digital droplet PCR; Digital PCR
MeSH headings : Bacteremia / diagnosis; Bacteremia / microbiology; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; DNA, Bacterial / isolation & purification; Humans; Real-Time Polymerase Chain Reaction / methods
TL;DR: The ddPCR assay developed based upon previously published TaqMan-based qPCR assays that can amplify DNA of over 25 Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: October 5, 2020

2020 journal article

Distribution and risk factors of canine haemotropic mycoplasmas in hunting dogs from southern Italy

VETERINARY MICROBIOLOGY, 251.

By: L. Cortese*, M. Beall*, F. Buono*, J. Buch*, L. Pacifico*, B. Neola*, A. Palatucci*, P. Tyrrell* ...

author keywords: Mycoplasma haemocanis; Candidatus mycoplasma haematoparvum; Hunting dogs; Italy
MeSH headings : Animals; DNA, Bacterial / genetics; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Female; Italy / epidemiology; Male; Mycoplasma / classification; Mycoplasma / genetics; Mycoplasma / isolation & purification; Mycoplasma / pathogenicity; Mycoplasma Infections / epidemiology; Mycoplasma Infections / veterinary; Prevalence; RNA, Ribosomal, 16S / genetics; Risk Factors; Tick Infestations / veterinary; Working Dogs / microbiology
TL;DR: Outdoor lifestyle and contact with wild fauna, through greater exposure to tick infestation, or possibly wounds acquired during hunting or fighting, could be factors contributing to haemoplasma infections. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: January 19, 2021

2020 journal article

Ehrlichia chaffeensis EplA Interaction With Host Cell Protein Disulfide Isomerase Promotes Infection

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 10.

By: R. Green*, J. Izac*, W. Naimi*, N. O'Bier*, E. Breitschwerdt n, R. Marconi*, J. Carlyon*

author keywords: Ehrlichia; protein disulfide isomerase; Intracellular bacteria; bacterial invasion; adhesin; anaplamataceae
MeSH headings : Adhesins, Bacterial; Animals; Dogs; Ehrlichia chaffeensis; Ehrlichiosis; Monocytes; Protein Disulfide-Isomerases
TL;DR: EplA contributes to E. chaffeensis infection of monocytic cells by engaging PDI and exploiting the enzyme's reduction of host cell surface disulfide bonds in an EplA C-terminus-dependent manner and is identified as a novel ehrlichial receptor binding domains. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: October 26, 2020

2020 journal article

Hepatozoon canisin hunting dogs from Southern Italy: distribution and risk factors

PARASITOLOGY RESEARCH, 119(9), 3023–3031.

By: L. Pacifico*, J. Braff*, F. Buono*, M. Beall*, B. Neola*, J. Buch*, G. Sgroi*, D. Piantedosi* ...

author keywords: Hepatozoon canis; Hunting dogs; Vector-borne diseases; Italy; PCR
TL;DR: The aims of the present survey were to determine the prevalence of H. canis in hunting dogs living in Southern Italy and to assess potential infection risk factors, as well as to assess the epidemiological relationships between hunting dogs and wild animal populations sharing the same habitats in SouthernItaly. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 17, 2020

2020 journal article

Imaging analysis of Bartonella species in the skin using single‐photon and multi‐photon (second harmonic generation) laser scanning microscopy

Clinical Case Reports.

By: A. Maluki*, E. Breitschwerdt n, L. Bemis*, R. Greenberg*, B. Mozayeni, J. Dencklau*, M. Ericson*

author keywords: Bartonella; confocal microscopy; psychiatric disorders; second harmonic generation; striae distensae
TL;DR: It is demonstrated Bartonella spp are abundant in skin lesions resembling striae distensae, coincidental with sudden onset of neuropsychiatric symptoms, indicate testing for suspected Bartonelli spp. (via Semantic Scholar)
Source: ORCID
Added: July 20, 2020

2020 journal article

Molecular prevalence of Bartonella, Babesia, and hemotropic Mycoplasma species in dogs with hemangiosarcoma from across the United States

PLOS ONE.

Ed(s): D. Thamm

MeSH headings : Animals; Babesia / genetics; Babesiosis / epidemiology; Babesiosis / parasitology; Bartonella / genetics; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; DNA, Bacterial / genetics; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Female; Hemangiosarcoma / epidemiology; Hemangiosarcoma / microbiology; Hemangiosarcoma / parasitology; Hemangiosarcoma / veterinary; Male; Mycoplasma / genetics; Mycoplasma Infections / epidemiology; Mycoplasma Infections / veterinary; Polymerase Chain Reaction; Prevalence; Retrospective Studies; United States / epidemiology
TL;DR: A high prevalence of Bartonella spp. (via Semantic Scholar)
Source: ORCID
Added: January 11, 2020

2020 journal article

Novel Rickettsia Species Infecting Dogs, United States

EMERGING INFECTIOUS DISEASES, 26(12), 3011–3015.

By: J. Wilson n, E. Breitschwerdt n, N. Juhasz n, H. Marr n, J. Galvao n, C. Pratt n, B. Qurollo n

MeSH headings : Animals; Dog Diseases / epidemiology; Dogs; Phylogeny; Rickettsia / genetics; Rickettsia Infections / epidemiology; Rickettsia Infections / veterinary; United States / epidemiology
TL;DR: Multilocus phylogenetic analysis showed the dogs were infected with a novel Rickettsia species related to humanRickettsia pathogens. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: February 15, 2021

2020 journal article

Validation of Bartonella henselae Western Immunoblotting for Serodiagnosis of Bartonelloses in Dogs

JOURNAL OF CLINICAL MICROBIOLOGY, 58(4).

By: P. Neupane n, S. Sevala n, N. Balakrishnan*, H. Marr n, J. Wilson n, R. Maggi n, A. Birkenheuer n, M. Lappin*, B. Chomel*, E. Breitschwerdt n

author keywords: serology; zoonosis; vector borne; Western blotting; antigen; Bartonella henselae
MeSH headings : Animals; Antibodies, Bacterial; Bartonella; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; Bartonella henselae; Blotting, Western; Dog Diseases / diagnosis; Dogs; Serologic Tests
TL;DR: This study characterized WB immunodominant proteins that could be used to confirm a serodiagnosis of canine bartonelloses using agar-grown Bartonella henselae San Antonio type 2 (SA2) whole-cell proteins, and found a strong but variable recognition of these proteins among 81% of group II dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 27, 2020

2019 review

An update on the treatment of canine monocytic ehrlichiosis (Ehrlichia canis)

[Review of ]. VETERINARY JOURNAL, 246, 45–53.

By: M. Mylonakis*, S. Harrus* & E. Breitschwerdt n

author keywords: Aplastic pancytopenia; Canine monocytic ehrlichiosis; Dog; Ehrlichia canis; Treatment
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Dog Diseases / drug therapy; Dogs; Ehrlichia canis; Ehrlichiosis / complications; Ehrlichiosis / drug therapy; Ehrlichiosis / veterinary; Pancytopenia / etiology; Pancytopenia / veterinary; Treatment Outcome
TL;DR: The current state of knowledge regarding treatment of ehrlichiosis, caused by E. canis infection in dogs, is reviewed, expert opinion guidelines for the management of the CME-associated aplastic pancytopenia are provided, and methods for evaluation of treatment outcomes are outlined. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 15, 2019

2019 journal article

Analysis of the antigenic determinants of the OspC protein of the Lyme disease spirochetes: Evidence that the C10 motif is not immunodominant or required to elicit bactericidal antibody responses

Vaccine, 37(17), 2401–2407.

By: J. Izac n, A. Camire n, C. Earnhart n, M. Embers n, R. Funk n, E. Breitschwerdt n, R. Marconi n

author keywords: Borreliella; Lyme disease; OspC; Lyme disease vaccine; Borrelia
MeSH headings : Animals; Antibodies, Bacterial / blood; Antibodies, Bacterial / immunology; Antibody Formation; Antigens, Bacterial / immunology; Bacterial Outer Membrane Proteins / immunology; Borrelia burgdorferi / immunology; Dogs; Enzyme-Linked Immunosorbent Assay; Epitopes / immunology; Horses; Humans; Lyme Disease / immunology; Lyme Disease / prevention & control; Primates; Rabbits; Recombinant Proteins / immunology; Vaccination
TL;DR: Insight is provided into the antigenic structure of OspC and it is demonstrated that the C10 motif does not significantly contribute to immunization or infection induced Ab responses in rabbits, rats, canines, horses and non-human primates. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: May 20, 2019

2019 journal article

Bartonella henselae Bloodstream Infection in a Boy With Pediatric Acute-Onset Neuropsychiatric Syndrome

Journal of Central Nervous System Disease, 11, 117957351983201.

By: E. Breitschwerdt n, R. Greenberg*, R. Maggi n, B. Mozayeni, A. Lewis & J. Bradley n

author keywords: Bacteria; psychosis; transmission; stretch marks; Bartonella; schizophrenia
TL;DR: This case report suggests that B henselae bloodstream infection may contribute to progressive, recalcitrant neuropsychiatric symptoms consistent with PANS in a subset of patients. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: April 9, 2019

2019 journal article

Clinicopathological findings in 41 dogs (2008‐2018) naturally infected with Ehrlichia ewingii

Journal of Veterinary Internal Medicine, 33(2), 618–629.

By: B. Qurollo n, J. Buch*, R. Chandrashekar*, M. Beall*, E. Breitschwerdt n, C. Yancey*, A. Caudill n, A. Comyn n

author keywords: canine; granulocytic ehrlichiosis; tick borne
MeSH headings : Animals; Antibodies, Bacterial / blood; Blood Cell Count / veterinary; Borrelia burgdorferi / immunology; Dog Diseases / blood; Dog Diseases / diagnosis; Dogs; Ehrlichia / immunology; Ehrlichia canis / immunology; Ehrlichiosis / diagnosis; Ehrlichiosis / veterinary; Female; Male; Retrospective Studies; Serologic Tests / veterinary
TL;DR: Renal disease, IMHA, proteinuria, neutrophilia, abnormal lymphocytes, and increased liver enzyme activities were common in this group of E. ewingii‐infected dogs and studies are needed to determine if E. Ewingii contributes to comorbidities or is a precipitating factor in clinical syndromes in persistently infected dogs. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: April 22, 2019

2019 journal article

Detection of Bartonella spp. in dogs after infection with Rickettsia rickettsii

Journal of Veterinary Internal Medicine, 34(1), 145–159.

By: E. Lashnits n, P. Neupane n, R. Maggi n, K. Linder n, J. Bradley n, N. Balakrishnan n, B. Southern n, G. McKeon n, R. Chandrashekar*, E. Breitschwerdt n

author keywords: PCR; recrudescence; serology; transmission
MeSH headings : Animals; Bartonella / isolation & purification; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Coinfection; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Female; Housing, Animal; Laboratory Animal Science; Rickettsia rickettsii; Rocky Mountain Spotted Fever / complications; Rocky Mountain Spotted Fever / microbiology; Rocky Mountain Spotted Fever / veterinary; Serologic Tests
TL;DR: The results support the possibilities of recrudescence of chronic subclinical Bartonella spp. (via Semantic Scholar)
Source: ORCID
Added: January 1, 2020

2019 journal article

Ecological and Socioeconomic Factors Associated with Bartonella henselae Exposure in Dogs Tested for Vector-Borne Diseases in North Carolina

Vector-Borne and Zoonotic Diseases, 19(8), 582–595.

By: E. Lashnits n, D. Dawson n, E. Breitschwerdt n & C. Lanzas n

author keywords: canine; seroreactivity; tick; flea; zoonoses; vector-borne
MeSH headings : Animals; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella henselae; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Ecosystem; Female; Male; North Carolina / epidemiology; Retrospective Studies; Risk Factors; Seroepidemiologic Studies; Socioeconomic Factors; Tick-Borne Diseases / epidemiology
TL;DR: Of 25 explanatory factors considered, the model combining demographic, socioeconomic, climatic, and land use variables fits best, and female intact sex and increasing percentage of the county with low-intensity development and evergreen forest were associated with higher seroreactivity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: June 4, 2019

2019 journal article

Evidence for vertical transmission of Mycoplasma haemocanis, but not Ehrlichia ewingii, in a dog

Journal of Veterinary Internal Medicine, 33(4), 1747–1752.

By: E. Lashnits n, S. Grant, B. Thomas n, B. Qurollo n & E. Breitschwerdt n

author keywords: bacterial species; hemotropic mycoplasma; perinatal; rickettsia; vector-borne
MeSH headings : Animals; Antibodies, Bacterial; Coinfection / veterinary; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Ehrlichia / isolation & purification; Ehrlichiosis / immunology; Ehrlichiosis / veterinary; Female; Infectious Disease Transmission, Vertical / veterinary; Male; Mycoplasma / isolation & purification; Mycoplasma Infections / transmission; Mycoplasma Infections / veterinary; Pregnancy
TL;DR: A potential role for vertical transmission in the maintenance of M. haemocanis in dogs as reservoir hosts is supported and there is no evidence that E. ewingii was transmitted transplacentally or during the perinatal period. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: May 27, 2019

2019 journal article

Molecular identification of vector-borne organisms in Ehrlichia seropositive Nicaraguan horses and first report of Rickettsia felis infection in the horse

ACTA TROPICA, 200.

By: J. Tyrrell n, B. Qurollo n, S. Tornquist*, K. Schlaich*, J. Kelsey*, R. Chandrashekar*, E. Breitschwerdt n

author keywords: Tick-borne disease; Equine rickettsiosis; Piroplasmosis; Babesia caballi; Theileria equi; Ehrlichia species H7
MeSH headings : Animals; Disease Vectors; Ehrlichia / genetics; Ehrlichia / isolation & purification; Ehrlichiosis / diagnosis; Ehrlichiosis / epidemiology; Horses / microbiology; Nicaragua / epidemiology; Rickettsia Infections / diagnosis; Rickettsia Infections / epidemiology; Rickettsia felis / genetics; Rickettsia felis / isolation & purification
TL;DR: To the authors' knowledge, this constitutes the first report of molecular detection of R. felis in horses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: December 16, 2019

2019 article

My Mother's Story: Tick Borne Ehrlichiosis and a Life Well-Lived

Breitschwerdt, E. B., & Maggi, R. G. (2020, May 1). VECTOR-BORNE AND ZOONOTIC DISEASES, Vol. 20, pp. 319–324.

By: E. Breitschwerdt n & R. Maggi n

author keywords: Ehrlichia; Bartonella; dementia; one health; non-Hodgkin's lymphoma
MeSH headings : Aged, 80 and over; Animals; Anti-Bacterial Agents / therapeutic use; Doxycycline / therapeutic use; Ehrlichia; Ehrlichiosis / diagnosis; Ehrlichiosis / drug therapy; Ehrlichiosis / epidemiology; Ehrlichiosis / pathology; Female; Humans; Maryland / epidemiology; Tick Bites; Ticks
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: May 18, 2020

2019 journal article

Prevalence of Babesia spp. and clinical characteristics of Babesia vulpes infections in North American dogs

Journal of Veterinary Internal Medicine, 7.

By: N. Barash n, B. Thomas n, A. Birkenheuer n, E. Breitschwerdt n, E. Lemler n & B. Qurollo n

author keywords: B; vulpes; Babesia; hemolytic anemia; prevalence; tick; vector-borne disease
MeSH headings : Animals; Babesia / classification; Babesia / isolation & purification; Babesiosis / epidemiology; Babesiosis / transmission; Coinfection / veterinary; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dog Diseases / pathology; Dogs; North America / epidemiology; Polymerase Chain Reaction / veterinary; Prevalence
TL;DR: The prevalence of Babesia sp. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 5, 2019

2019 journal article

Pyogranulomatous Myocarditis and Diaphragmatic Myositis Associated with Bartonella Henselae in a Cat From Turkey

Ankara Üniversitesi Veteriner Fakültesi Dergisi, 66(1), 103–107.

By: M. Gulbahar, E. Karaca, A. Ciftci, S. Inal, I. Ahmed, N. Balakrishnan, E. Breitshwerdt

TL;DR: Evidence is provided in support of an etiological association between pyogranulomatous myocarditis and diaphragmatic myositis and B. henselae infection in cats. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 13, 2019

2019 journal article

Trait-performance relationships of grassland plant species differ between common garden and field conditions

Ecology and Evolution, 9(4), 1691–1701.

author keywords: common garden experiment; land-use; managed grassland; plant functional traits; plant performance; relative growth rates
TL;DR: The ability to reproduce vegetatively, having leaves that are summer‐persistent and with high leaf dry matter content were traits of major importance under both settings, albeit the magnitude of their influence differed slightly between the field and the common garden experiment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 8, 2019

2018 journal article

Babesia gibsoni cytochrome b mutations in canine blood samples submitted to a US veterinary diagnostic laboratory

Journal of Veterinary Internal Medicine, 32(6), 1965–1969.

By: A. Birkenheuer n, H. Marr n, J. Wilson n, E. Breitschwerdt n & B. Qurollo n

author keywords: atovaquone; mitochondrial; pharmacogenomics; resistance
MeSH headings : Animals; Babesia / genetics; Babesiosis / blood; Babesiosis / epidemiology; Babesiosis / parasitology; Cytochromes b / genetics; Dog Diseases / blood; Dog Diseases / epidemiology; Dog Diseases / parasitology; Dogs; Mutation / genetics; Pathology, Veterinary / statistics & numerical data; Prevalence; Real-Time Polymerase Chain Reaction / veterinary; United States / epidemiology
TL;DR: The study reaffirms that B. gibsoni infection is widespread and most commonly detected in American Staffordshire Terrier/American Pit Bull Terrier dogs and that the prevalence of cytb mutations does not warrant pretreatment genotyping. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: December 31, 2018

2018 journal article

Bartonella henselae in a dog with ear tip vasculitis

Veterinary Dermatology, 29(6), 537–e180.

By: B. Southern n, P. Neupane n, M. Ericson*, J. Dencklau*, K. Linder n, J. Bradley n, G. McKeon n, C. Long*, E. Breitschwerdt n

MeSH headings : Animals; Bartonella henselae / genetics; Cat-Scratch Disease / pathology; Cat-Scratch Disease / veterinary; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Ear, External / microbiology; Ear, External / pathology; Female; Polymerase Chain Reaction / veterinary; Vasculitis / diagnosis; Vasculitis / pathology; Vasculitis / veterinary
TL;DR: Bartonella henselae is an emerging zoonotic pathogen that has been associated with leucocytoclastic vasculitis in humans and may have had a contributing or causative role in the development of the cutaneous aural margin vasculopathy in this beagle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: November 26, 2018

2018 journal article

Bartonella henselae infection in a dog with recalcitrant ineffective erythropoiesis

Veterinary Clinical Pathology, 47(1), 45–50.

By: M. Randell, N. Balakrishnan n, R. Gunn-Christie, A. Mackin* & E. Breitschwerdt n

author keywords: Bartonella henselae; bone marrow dyscrasia; immunosuppression; ineffective erythropoiesis
TL;DR: The contribution of B henselae bacteremia to ineffective erythropoiesis remains unknown; however, the potential role of B Henselae in the pathophysiology of bone marrow dyscrasias warrants additional investigation. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2018 journal article

Bartonella henselae in small Indian mongooses ( Herpestes auropunctatus ) from Grenada, West Indies

Veterinary Microbiology, 216, 119–122.

By: D. Jaffe*, B. Chomel*, R. Kasten*, E. Breitschwerdt n, R. Maggi n, A. McLeish*, U. Zieger*

author keywords: Bartonella henselae; Herpestes auropunctatus; Small Indian mongoose; Grenada Island
MeSH headings : Angiomatosis, Bacillary / epidemiology; Angiomatosis, Bacillary / microbiology; Animals; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Bartonella henselae / physiology; Disease Reservoirs / microbiology; Genotype; Grenada / epidemiology; Herpestidae / microbiology; Zoonoses / epidemiology; Zoonoses / microbiology
TL;DR: The role of small Indian mongooses as a natural reservoir of B. henselae in the New World is confirmed and documented to identify a potential source of zoonotic risk with mongoose-human contact in theNew World. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2018 journal article

Bartonella infections in cats and dogs including zoonotic aspects

Parasites & Vectors, 11(1).

By: A. Álvarez-Fernández*, E. Breitschwerdt n & L. Solano-Gallego*

author keywords: Bartonella; Dog; Cat; Europe; Zoonosis
MeSH headings : Animals; Bartonella / classification; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / transmission; Bartonella Infections / veterinary; Cat Diseases / diagnosis; Cat Diseases / microbiology; Cat Diseases / pathology; Cat Diseases / therapy; Cats; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dog Diseases / pathology; Dog Diseases / therapy; Dogs; Europe / epidemiology; Humans; Prevalence; Zoonoses / epidemiology; Zoonoses / microbiology; Zoonoses / transmission
TL;DR: An update and European perspective on Bartonella infections in cats and dogs, including clinical, diagnostic, epidemiological, pathological, treatment and zoonotic aspects is provided. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: December 17, 2018

2018 journal article

Bartonella quintana and Bartonella vinsonii subsp. vinsonii bloodstream co-infection in a girl from North Carolina, USA

Medical Microbiology and Immunology, 208(1), 101–107.

By: E. Breitschwerdt n & R. Maggi n

author keywords: Bartonella quintana; Bartonella vinsonii subsp; vinsonii; Bacteria; Vector; Equestrian
MeSH headings : Adolescent; Bacteremia / diagnosis; Bacteremia / microbiology; Bacteremia / pathology; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonellaceae Infections / diagnosis; Bartonellaceae Infections / microbiology; Bartonellaceae Infections / pathology; Cluster Analysis; Coinfection / diagnosis; Coinfection / microbiology; Coinfection / pathology; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Ribosomal Spacer / chemistry; DNA, Ribosomal Spacer / genetics; Female; Humans; Microbiological Techniques; Molecular Diagnostic Techniques; North Carolina; Phylogeny; Sequence Analysis, DNA; Serologic Tests
TL;DR: The first documented human case of blood stream infection with Bartonella vinsonii subsp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: February 4, 2019

2018 journal article

Bartonella spp. Bloodstream Infection in a Canadian Family

Vector-Borne and Zoonotic Diseases, 19(4), 234–241.

By: E. Breitschwerdt n, R. Maggi n, C. Quach* & J. Bradley n

author keywords: infection; bacteria; family; transmission; vectors
MeSH headings : Adult; Bacteremia / microbiology; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / microbiology; Canada; Child; Family; Female; Humans; Male; Real-Time Polymerase Chain Reaction
TL;DR: There is a substantial need for clinical research to clarify the extent to which Bartonella spp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: April 15, 2019

2018 journal article

Bartonella spp. as a Possible Cause or Cofactor of Feline Endomyocarditis–Left Ventricular Endocardial Fibrosis Complex

Journal of Comparative Pathology, 162, 29–42.

By: T. Donovan*, N. Balakrishnan*, I. Carvalho Barbosa, T. McCoy n, E. Breitschwerdt n & P. Fox*

author keywords: Barlonella; cat; endocardial fibrosis; endomyocarditis
MeSH headings : Animals; Bartonella; Bartonella Infections / veterinary; Cat Diseases / microbiology; Cats; DNA, Bacterial / analysis; Endocarditis, Bacterial / veterinary; Myocarditis / veterinary
TL;DR: The hypothesis that Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: September 11, 2019

2018 journal article

Comparative Evaluation of 2 In-Clinic Assays for Vector-Borne Disease Testing in Dogs

TOPICS IN COMPANION ANIMAL MEDICINE, 33(4), 114–118.

By: J. Liu*, J. Drexel*, B. Andrews*, M. Eberts*, E. Breitschwerdt n & R. Chandrashekar*

author keywords: SNAP 4Dx plus; FLEX4; tick-borne disease; heartworm disease; in-clinic assays; serology
MeSH headings : Anaplasma / immunology; Anaplasmosis / blood; Anaplasmosis / diagnosis; Animals; Antibodies, Bacterial / blood; Antibodies, Helminth / blood; Borrelia burgdorferi / immunology; Dirofilaria immitis / immunology; Dirofilariasis / diagnosis; Dog Diseases / blood; Dog Diseases / diagnosis; Dogs; Ehrlichia / immunology; Ehrlichiosis / blood; Ehrlichiosis / diagnosis; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay / methods; Enzyme-Linked Immunosorbent Assay / veterinary; Lyme Disease / blood; Lyme Disease / diagnosis; Lyme Disease / veterinary; Sensitivity and Specificity; Tick-Borne Diseases / diagnosis; Tick-Borne Diseases / veterinary
TL;DR: Based upon the comparative results derived from this study, the SNAP test was more sensitive than the FLEX4 test for detection of antibodies to all tick‐borne pathogens and heartworm disease (Dirofilaria immitis) antigen in dogs. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 21, 2019

2018 journal article

Distribution and risk factors associated with Babesia spp. infection in hunting dogs from Southern Italy

TICKS AND TICK-BORNE DISEASES, 9(6), 1459–1463.

By: V. Veneziano*, D. Piantedosi*, N. Ferrari*, B. Neola*, M. Santoro*, L. Pacifico*, G. Sgroi*, N. D'Alessio* ...

author keywords: Babesia canis; Babesia vogeli; Babesia gibsoni; Hunting dogs; Italy
MeSH headings : Animals; Babesia / classification; Babesia / isolation & purification; Babesia / physiology; Babesiosis / epidemiology; Babesiosis / parasitology; Dog Diseases / epidemiology; Dog Diseases / parasitology; Dogs; Italy / epidemiology; Prevalence; Risk Factors; Seroepidemiologic Studies
TL;DR: The aim of this survey was to determine the prevalence and risk factors associated with Babesia species infections in hunting dogs from Southern Italy, and to evaluate the potential epidemiological relationships between hunting dogs and wild animal populations sharing the same area. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 16, 2018

2018 journal article

Evaluation of cell culture-grown Bartonella antigens in immunofluorescent antibody assays for the serological diagnosis of bartonellosis in dogs

Journal of Veterinary Internal Medicine, 32(6), 1958–1964.

By: P. Neupane n, B. Hegarty n, H. Marr n, R. Maggi n, A. Birkenheuer n & E. Breitschwerdt n

author keywords: bacteria; BAPGM; serology; vector-borne; zoonosis
MeSH headings : Animals; Antigens, Bacterial / immunology; Bartonella / immunology; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; Bartonella henselae / immunology; Bartonella quintana / immunology; Cells, Cultured; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Fluorescent Antibody Technique / methods; Fluorescent Antibody Technique / veterinary; Polymerase Chain Reaction / veterinary; Sensitivity and Specificity; Serologic Tests / methods; Serologic Tests / veterinary; Trench Fever / diagnosis; Trench Fever / veterinary
TL;DR: Despite IFA testing of dogs against 8 different Bartonella isolates, IFA sensitivity remained poor, and specificity was only 85%. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: December 31, 2018

2018 journal article

Identification of Hemotropic Mycoplasmas in an Eastern Box Turtle (Terrapene carolina carolina) and a Yellow-bellied Slider (Trachemys scripta scripta) from North Carolina, USA

Journal of Wildlife Diseases, 54(2), 371–374.

By: J. Jarred n, G. Lewbart n, K. Stover n, B. Thomas n, R. Maggi n & E. Breitschwerdt n

author keywords: Chelonian; hemoplasma; hemotropic mycoplasma; PCR; wildlife
MeSH headings : Animals; Mycoplasma / classification; Mycoplasma / genetics; Mycoplasma / isolation & purification; Mycoplasma Infections / epidemiology; Mycoplasma Infections / microbiology; Mycoplasma Infections / veterinary; North Carolina / epidemiology; Phylogeny; Turtles / microbiology
TL;DR: Based upon sequencing of the 16S rRNA subunit, one eastern box turtle and one yellow-bellied slider were infected with Mycoplasma spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2018 journal article

Improvement of Bartonella henselae DNA Detection in Cat Blood Samples by Combining Molecular and Culture Methods

Journal of Clinical Microbiology, 56(5).

By: M. Drummond*, B. Lania*, P. Diniz*, R. Gilioli*, D. Demolin*, D. Scorpio*, E. Breitschwerdt n, P. Velho*

Ed(s): B. Fenwick

author keywords: bacteremia; Bartonella; cats; diagnosis; PCR
MeSH headings : Animals; Bacteremia / diagnosis; Bacteremia / microbiology; Bacteremia / veterinary; Bacterial Proteins / genetics; Bartonella Infections / blood; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; Bartonella henselae / genetics; Blood Culture; Cat Diseases / blood; Cat Diseases / diagnosis; Cats; Cytoskeletal Proteins / genetics; DNA, Bacterial / blood; DNA, Bacterial / genetics; Molecular Diagnostic Techniques; Polymerase Chain Reaction; Sensitivity and Specificity; Sequence Analysis, DNA
TL;DR: The frequency of bloodstream infection in 112 cats in southeastern Brazil is determined by comparing and combining the results of multiple conventional and nested PCRs from blood and liquid culture samples, indicating that PCR testing of more than one type of sample provides better sensitivity than a standalone PCR. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2018 journal article

Molecular and Serological Prevalence of Anaplasma phagocytophilum, A. platys, Ehrlichia canis, E. chaffeenses, E. ewingii, Borrelia burgdorferi, Babesia canis, B. gibsoni and B. vogeli among Clinically Healthy Outdoor Dogs in Serbia

Veterinary Parasitology: Regional Studies and Reports, 14, 117–122.

author keywords: Molecular prevalence; seroprevalence; Tick-borne pathogens; Dogs; Serbia
MeSH headings : Anaplasma phagocytophilum / genetics; Anaplasmosis / epidemiology; Animals; Animals, Wild; Antibodies, Bacterial / blood; Babesia / genetics; Borrelia burgdorferi / genetics; Disease Reservoirs / microbiology; Disease Reservoirs / parasitology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs / microbiology; Dogs / parasitology; Ehrlichia canis / genetics; Ehrlichiosis / veterinary; Female; Lyme Disease / veterinary; Male; Polymerase Chain Reaction; Prevalence; Serbia / epidemiology; Seroepidemiologic Studies; Tick-Borne Diseases / epidemiology
TL;DR: It is concluded that outdoor dogs in this territory are reservoirs for B. canis and B. gibsoni and are frequently co-exposed to combinations of Anaplasma and Babesia spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, ORCID
Added: September 11, 2019

2018 journal article

Molecular surveillance of novel tick-borne organisms in Madagascar's lemurs

TICKS AND TICK-BORNE DISEASES, 9(3), 672–677.

By: B. Qurollo n, P. Larsen*, H. Rakotondrainibe, K. Mahefarisoa*, T. Rajaonarivelo, J. Razafindramanana, E. Breitschwerdt n, R. Junge*, C. Williams*

author keywords: Babesia; Borrelia; Neoehrlichia; Lemurs; Madagascar; One health
MeSH headings : Animals; Babesia / genetics; Babesia / isolation & purification; Babesia / pathogenicity; Babesiosis / epidemiology; Babesiosis / parasitology; Borrelia / genetics; Borrelia / isolation & purification; Borrelia / pathogenicity; Humans; Ixodes / microbiology; Lemur / microbiology; Lemur / parasitology; Lyme Disease / epidemiology; Lyme Disease / microbiology; Lyme Disease / veterinary; Madagascar / epidemiology; One Health; Tick-Borne Diseases / epidemiology; Tick-Borne Diseases / microbiology; Tick-Borne Diseases / parasitology; Tick-Borne Diseases / veterinary; Zoonoses / epidemiology; Zoonoses / microbiology; Zoonoses / parasitology
TL;DR: This study lends support to the One Health concept by highlighting the prevalence of three blood-borne organisms in wild lemurs living in close proximity to domesticated species and humans in Madagascar. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

Pasteurella canis infective endocarditis in a dog

Veterinary Microbiology, 229, 14–19.

By: Z. Kern n, O. Swartley n, P. Neupane n, N. Balakrishnan n & E. Breitschwerdt n

author keywords: Pasteurella cards; Infective vegetative endocarditis; Sepsis; Vasculitis; 16S rDNA PCR; MAIDLTOF
MeSH headings : Animals; Dog Diseases / microbiology; Dogs; Endocarditis, Bacterial / microbiology; Fatal Outcome; Male; Pasteurella / classification; Pasteurella Infections / microbiology; Pasteurella Infections / veterinary
TL;DR: The goal of this study is to detail the clinical presentation and microbiological findings associated with a novel causative agent of infective endocarditis in the dog. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: February 18, 2019

2018 journal article

Potentially Same Novel Ehrlichia Species in Horses in Nicaragua and Brazil

Emerging Infectious Diseases, 24(5), 953–953.

MeSH headings : Animals; Brazil / epidemiology; Ehrlichia / classification; Ehrlichiosis / epidemiology; Ehrlichiosis / parasitology; Ehrlichiosis / veterinary; Horse Diseases / epidemiology; Horse Diseases / parasitology; Horses; Nicaragua / epidemiology
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2018 journal article

Regional prevalences of Borrelia burgdorferi, Borrelia bissettiae, and Bartonella henselae in Ixodes affinis, Ixodes pacificus and Ixodes scapularis in the USA

Ticks and Tick-Borne Diseases, 10(2), 360–364.

By: R. Maggi n, M. Toliver*, T. Richardson n, T. Mather* & E. Breitschwerdt n

author keywords: Borrelia; B. bissettiae; Bartonella; Ixodes; I.affinis; I. scapularis
MeSH headings : Angiomatosis, Bacillary / epidemiology; Animals; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Borrelia / genetics; Borrelia / isolation & purification; Borrelia burgdorferi / genetics; Borrelia burgdorferi / isolation & purification; Coinfection / epidemiology; Coinfection / microbiology; DNA, Bacterial / genetics; Ixodes / microbiology; Lyme Disease / epidemiology; Minnesota / epidemiology; North Carolina / epidemiology; Polymerase Chain Reaction; Prevalence; Sequence Analysis, DNA; United States / epidemiology
TL;DR: Improved understanding of the enzootic cycle, transmission dynamics, and vector competence of Ixodes species (especially I. affinis) for transmission of Borrelia spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: February 4, 2019

2018 journal article

Rheumatological presentation of Bartonella koehlerae and Bartonella henselae bacteremias

Medicine, 97(17), e0465.

By: B. Mozayeni n, R. Maggi n, J. Bradley n & E. Breitschwerdt n

author keywords: Bartonella henselae; Bartonella koehlerae; bartonellosis; breast cyst; EDS Ehlers-Danlos; joint laxity; serology
MeSH headings : Adult; Anti-Bacterial Agents / therapeutic use; Antibodies, Bacterial / blood; Bacteremia / diagnosis; Bacteremia / drug therapy; Bacteremia / physiopathology; Bartonella Infections / diagnosis; Bartonella Infections / drug therapy; Bartonella Infections / physiopathology; Diagnosis, Differential; Ehlers-Danlos Syndrome / diagnosis; Ehlers-Danlos Syndrome / physiopathology; Female; Humans; Polymerase Chain Reaction; Rheumatic Diseases / diagnosis; Rheumatic Diseases / physiopathology; Sequence Analysis, DNA
TL;DR: To facilitate early and directed medical interventions, systemic bartonellosis should potentially be considered as a differential diagnosis in patients with incalcitrant rheumatological symptoms and frequent arthropod exposures or extensive animal contact. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2018 journal article

Using co-occurrence information and trait composition to understand individual plant performance in grassland communities

Scientific Reports, 8(1).

MeSH headings : Algorithms; Biomass; Ecosystem; Grassland; Models, Theoretical; Plant Leaves / growth & development; Plants / classification; Plants / metabolism; Seasons; Species Specificity
TL;DR: The two-year field experiment investigated the relative growth rates of 130 species that had been transplanted into German grassland communities varying in intensities of land-use, demonstrating a limited temporal validity of performance models. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 8, 2019

2017 journal article

Antimicrobial use Guidelines for Treatment of Respiratory Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases

Journal of Veterinary Internal Medicine, 31(2), 279–294.

By: M. Lappin*, J. Blondeau*, D. Boothe*, E. Breitschwerdt n, L. Guardabassi*, D. Lloyd*, M. Papich n, S. Rankin* ...

author keywords: Bronchitis; Pneumonia; Pyothorax; Rhinitis
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacterial Infections / drug therapy; Bacterial Infections / veterinary; Cat Diseases / drug therapy; Cats; Dog Diseases / drug therapy; Dogs; Respiratory Tract Diseases / drug therapy; Respiratory Tract Diseases / veterinary
TL;DR: The International Society for Companion Animal Infectious Diseases convened a Working Group of clinical microbiologists, pharmacologists, and internists to share experiences, examine scientific data, review clinical trials, and develop these guidelines to assist veterinarians in making antimicrobial treatment choices. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Bartonella Seroepidemiology in Dogs from North America, 2008-2014

Journal of Veterinary Internal Medicine, 32(1), 222–231.

By: E. Lashnits n, M. Correa n, B. Hegarty n, A. Birkenheuer n & E. Breitschwerdt n

author keywords: Canine; Seroreactivity; Zoonoses
MeSH headings : Animals; Bartonella; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Female; Fluorescent Antibody Technique, Indirect / veterinary; Male; North America / epidemiology; Seroepidemiologic Studies; Spatio-Temporal Analysis
TL;DR: Male intact dogs, mixed breed dogs, and dogs exposed to other CVBD have higher seroreactivity to multiple Bartonella species, and geographic patterns supported broad distribution of exposure, and co‐exposure with otherCVBD was common. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Bartonella henselae in canine cavitary effusions: prevalence, identification, and clinical associations

Veterinary Clinical Pathology, 46(2), 326–330.

By: A. Weeden*, N. Cherry*, E. Breitschwerdt n, A. Cheves* & H. Wamsley*

author keywords: Bartonellosis; dog; peritoneal effusion; pleural effusion; seasonal variation
MeSH headings : Angiomatosis, Bacillary / diagnosis; Angiomatosis, Bacillary / epidemiology; Angiomatosis, Bacillary / pathology; Angiomatosis, Bacillary / veterinary; Animals; Ascitic Fluid / microbiology; Bartonella henselae; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Female; Male; Pericardial Effusion / etiology; Pericardial Effusion / microbiology; Pericardial Effusion / veterinary; Pleural Effusion / etiology; Pleural Effusion / microbiology; Pleural Effusion / veterinary; Prevalence; Seasons
TL;DR: Viable B henselae organisms occur in pleural and peritoneal effusions of dogs; the clinical relevance of which remains unclear and may represent opportunistic infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Bartonellosis, One Health and all creatures great and small

Veterinary Dermatology, 28(1), 96–e21.

By: E. Breitschwerdt n

MeSH headings : Animals; Bartonella; Bartonella Infections / diagnosis; Bartonella Infections / etiology; Bartonella Infections / therapy; Bartonella Infections / veterinary; Communicable Diseases, Emerging / diagnosis; Communicable Diseases, Emerging / therapy; Communicable Diseases, Emerging / veterinary; Humans; Zoonoses / diagnosis; Zoonoses / microbiology; Zoonoses / therapy; Zoonoses / transmission
TL;DR: This review serves as an update on comparative medical aspects of this disease, including the epidemiology, pathogenesis, clinical diagnosis, treatment and challenges, and concludes that directed Bartonella research could substantially reduce a spectrum of chronic and debilitating animal and human diseases, and thereby reduce suffering throughout the world. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Death of Military Working Dogs Due to Bartonella vinsonii Subspecies berkhoffii Genotype III Endocarditis and Myocarditis

MILITARY MEDICINE, 182(3-4), E1864–E1869.

By: L. Shelnutt n, N. Balakrishnan n, J. DeVanna, K. Batey* & E. Breitschwerdt n

MeSH headings : Animals; Bartonellaceae / pathogenicity; Bartonellaceae Infections / complications; Bartonellaceae Infections / diagnosis; Bartonellaceae Infections / veterinary; Dog Diseases / diagnosis; Dogs; Endocarditis / etiology; Endocarditis / veterinary; Female; Male; Military Personnel; Myocarditis / etiology; Myocarditis / veterinary
TL;DR: Comprehensive periodic screening for canine vector-borne infections, in particular occult infections caused by Bartonella spp, is prudent to avoid serious or life-threating illnesses. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 journal article

Doxycycline treatment efficacy in dogs with naturally occurring Anaplasma phagocytophilum infection

Journal of Small Animal Practice, 59(5), 286–293.

By: C. Yancey n, P. Diniz*, E. Breitschwerdt n, B. Hegarty n, C. Wiesen* & B. Qurollo n

MeSH headings : Anaplasma phagocytophilum / drug effects; Anaplasma phagocytophilum / genetics; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / therapeutic use; DNA, Bacterial / blood; DNA, Bacterial / isolation & purification; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Doxycycline / administration & dosage; Doxycycline / therapeutic use; Ehrlichiosis / veterinary; Lymph Nodes / microbiology; Polymerase Chain Reaction / veterinary; United States
TL;DR: The results of this study support the efficacy of doxycycline therapy for clinical treatment of dogs naturally infected with A. phagocytophilum in the USA. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Improved molecular detection of Babesia infections in animals using a novel quantitative real-time PCR diagnostic assay targeting mitochondrial DNA

Parasites & Vectors, 10(1).

By: B. Qurollo n, N. Archer n, M. Schreeg n, H. Marr n, A. Birkenheuer n, K. Haney n, B. Thomas n, E. Breitschwerdt n

author keywords: Canine babesiosis; Babesia; Mitochondrial DNA; Quantitative PCR
MeSH headings : Animals; Babesia / classification; Babesiosis / diagnosis; Babesiosis / parasitology; DNA, Mitochondrial / genetics; DNA, Protozoan / genetics; Real-Time Polymerase Chain Reaction / methods; Real-Time Polymerase Chain Reaction / veterinary
TL;DR: A more sensitive qPCR assay with a more expansive range of Babesia spp. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Nasogastric tube-administered alectinib achieved long-term survival in a crizotinib-refractory nonsmall cell lung cancer patient with a poor performance status

Clinical Case Reports, 5(6), 931–935.

By: D. Kaufman, A. Kogelnik, R. Mozayeni, N. Cherry & E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Neurological and immunological dysfunction in two patients with Bartonella henselae bacteremia

Clinical Case Reports, 5(6), 931–935.

By: D. Kaufman*, A. Kogelnik*, R. Mozayeni*, N. Cherry* & E. Breitschwerdt n

author keywords: Bartonella; immune dysfunction; Infection; neurological symptoms; vectorborne
TL;DR: Neurobartonellosis should be among the differential diagnoses for patients with persistent or recurrent neurological symptoms of undetermined etiology and microbiological and immunological testing should be concurrently pursued to determine whether defective immune function accompanies Bartonella bacteremia. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Prevalence of Bartonella spp. by culture, PCR and serology, in veterinary personnel from Spain

Parasites & Vectors, 10(1).

author keywords: Bartonella alphaproteobacteria growth medium; Bartonella henselae; Bartonella quintana; Bartonella vinsonii berkhoffii; Bartonella koehlerae; Veterinary personnel; Spain
MeSH headings : Animal Technicians; Animals; Antibodies, Bacterial / blood; Bartonella / genetics; Bartonella / immunology; Bartonella / isolation & purification; Bartonella / physiology; Bartonella Infections / diagnosis; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / transmission; Bartonella henselae / genetics; Bartonella henselae / growth & development; Bartonella henselae / immunology; Bartonella henselae / physiology; Cross-Sectional Studies; DNA, Bacterial / genetics; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Female; Fluorescent Antibody Technique; Genotype; Humans; Male; Prevalence; Real-Time Polymerase Chain Reaction; Sequence Analysis, DNA; Seroepidemiologic Studies; Spain / epidemiology; Surveys and Questionnaires; Veterinarians; Zoonoses
TL;DR: High serological and molecular prevalences of exposure to, or infection with, Bartonella spp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Prevalence of Vector-Borne Pathogens in Southern California Dogs With Clinical and Laboratory Abnormalities Consistent With Immune-Mediated Disease

Journal of Veterinary Internal Medicine, 31(4), 1081–1090.

By: L. Kidd*, B. Qurollo n, M. Lappin*, K. Richter*, J. Hart*, S. Hill*, C. Osmond*, E. Breitschwerdt n

author keywords: Anaplasmosis; Babesiosis; Ehrlichiosis; Flea; Immune-mediated; Rickettsioses; Tick
MeSH headings : Animals; Babesia; Babesiosis / diagnosis; Babesiosis / epidemiology; Babesiosis / immunology; California / epidemiology; Disease Vectors; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / immunology; Dogs; Ehrlichia; Ehrlichiosis / diagnosis; Ehrlichiosis / epidemiology; Ehrlichiosis / immunology; Ehrlichiosis / veterinary; Female; Male; Prevalence; Real-Time Polymerase Chain Reaction / veterinary
TL;DR: Repeated testing using serology and PCR enhances detection of infection by vector‐borne pathogens in dogs with clinical signs of immune‐mediated disease. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Sensitivity and specificity levels of two rapid assays for antibodies to Anaplasma spp. in dogs

Journal of Veterinary Diagnostic Investigation, 30(2), 290–293.

By: J. Liu n, M. Eberts n, H. Bewsey n, T. O’Connor n, R. Chandrashekar n & E. Breitschwerdt n

author keywords: Anaplasma phagocytophilum; dogs; tick-borne diseases
MeSH headings : Anaplasma / immunology; Anaplasma phagocytophilum / immunology; Anaplasmosis / blood; Anaplasmosis / epidemiology; Anaplasmosis / microbiology; Animals; Antibodies, Bacterial / blood; Dog Diseases / blood; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Enzyme-Linked Immunosorbent Assay / methods; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Fluorescent Antibody Technique, Indirect / methods; Fluorescent Antibody Technique, Indirect / veterinary; Male; Reagent Kits, Diagnostic / veterinary; Sensitivity and Specificity; Tick-Borne Diseases / epidemiology; Tick-Borne Diseases / veterinary; United States / epidemiology
TL;DR: The SNAP 4Dx Plus test and the VetScan Canine Anaplasmosis Rapid test are commercial in-house rapid tests for the detection of antibody to these 2 antigenically related Anaplasma species and demonstrate significantly higher sensitivity and specificity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Seroprevalence and risk factors associated with Ehrlichia canis, Anaplasma spp., Borrelia burgdorferi sensu lato, and D. immitis in hunting dogs from southern Italy

Parasitology Research, 116(10), 2651–2660.

By: D. Piantedosi*, B. Neola*, N. D’Alessio*, F. Di Prisco*, M. Santoro*, L. Pacifico*, G. Sgroi*, L. Auletta* ...

author keywords: Ehrlichia canis; Anaplasma spp; Borrelia burgdorferi; Dirofilaria immitis; Hunting dogs; Italy
MeSH headings : Anaplasma; Anaplasmosis / epidemiology; Animals; Borrelia burgdorferi; Dirofilaria immitis; Dirofilariasis / epidemiology; Disease Vectors; Dog Diseases / epidemiology; Dog Diseases / etiology; Dogs; Ehrlichia canis; Ehrlichiosis / epidemiology; Ehrlichiosis / etiology; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay; Female; Italy / epidemiology; Lyme Disease / epidemiology; Lyme Disease / veterinary; Male; Risk Factors; Seroepidemiologic Studies
TL;DR: The results of the present survey indicated that hunting dog populations are at relative risk of CVBDs in southern Italy and the historical presence of tick infestation was identified as a risk factor for positivity to E. canis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Seroprevalence of Bartonella species, Coxiella burnetii and Toxoplasma gondii among patients with hematological malignancies: A pilot study in Romania

Zoonoses and Public Health, 64(6), 485–490.

author keywords: Bartonella; Coxiella burnetii; immunocompromised patients; livestock; seroprevalence; Toxoplasma; zoonoses
MeSH headings : Adult; Animals; Bartonella / isolation & purification; Bartonella Infections / complications; Bartonella Infections / epidemiology; Coxiella / isolation & purification; Female; Humans; Leukemia / complications; Leukemia / epidemiology; Male; Middle Aged; Q Fever / complications; Q Fever / epidemiology; Risk Factors; Romania / epidemiology; Seroepidemiologic Studies; Toxoplasma / isolation & purification; Toxoplasmosis / complications; Toxoplasmosis / epidemiology; Zoonoses
TL;DR: Patients receiving immunosuppressive cancer treatments in settings where there is a high degree of human–animal interaction may be at increased risk for opportunistic zoonotic infections or reactivation of latent infections, particularly with respect to Bartonella species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Vector-borne and zoonotic diseases of dogs in North-west New South Wales and the Northern Territory, Australia

BMC Veterinary Research, 13(1).

By: A. Shapiro*, G. Brown*, J. Norris*, K. Bosward*, D. Marriot*, N. Balakrishnan n, E. Breitschwerdt n, R. Malik*

author keywords: Dog; Babesia spp.; Anaplasma spp.; Haemotropic mycoplasmas; Coxiella burnetii; Bartonella spp.; Brucella spp.
MeSH headings : Anaplasma / isolation & purification; Anemia / veterinary; Animals; Babesia / isolation & purification; Coxiella burnetii / isolation & purification; DNA, Bacterial; DNA, Protozoan; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Humans; Mycoplasma / isolation & purification; New South Wales / epidemiology; Northern Territory / epidemiology; Protozoan Infections, Animal / epidemiology; Real-Time Polymerase Chain Reaction; Thrombocytopenia / veterinary; Zoonoses / epidemiology; Zoonoses / microbiology; Zoonoses / parasitology
TL;DR: Vector-borne pathogens occur in dogs free ranging near Aboriginal communities, with higher detection rates in NT than N-W NSW, and work needs to be extended to tropical coastal communities where fleas are present as well as ticks. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Bartonella henselae, Bartonella koehlerae and Rickettsia rickettsii seroconversion and seroreversion in a dog with acute-onset fever, lameness, and lymphadenopathy followed by a protracted disease course

Veterinary Parasitology: Regional Studies and Reports, 7, 19–24.

By: E. Golly n, E. Breitschwerdt n, N. Balakrishnan n, D. Moore* & P. Bizikova n

TL;DR: Following recent tick exposure in Arkansas, a 2-year-old, female spayed Labradoodle was examined because of a one-week history of lethargy and shifting-leg lameness, and therapeutic elimination of all three pathogens was seemingly achieved. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 11, 2019

2016 journal article

Culture, PCR, DNA sequencing, and second harmonic generation (SHG) visualization of Bartonella henselae from a surgically excised human femoral head

Clinical Rheumatology, 36(7), 1669–1675.

By: M. Ericson*, N. Balakrishnan n, B. Mozayeni, C. Woods*, J. Dencklau*, S. Kelly, E. Breitschwerdt n

MeSH headings : Bartonella henselae / isolation & purification; Cat-Scratch Disease / complications; Cat-Scratch Disease / diagnosis; Female; Humans; Middle Aged; Osteoarthritis, Hip / microbiology; Second Harmonic Generation Microscopy
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Infective endocarditis in 13 cats

Journal of Veterinary Cardiology, 18(3), 213–225.

By: J. Palerme*, A. Jones*, J. Ward*, N. Balakrishnan n, K. Linder n, E. Breitschwerdt n, B. Keene n

author keywords: BAPGM; Bartonella; Duke criteria; Vegetative lesion
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cat Diseases / physiopathology; Cats; Endocarditis, Bacterial / diagnosis; Endocarditis, Bacterial / drug therapy; Endocarditis, Bacterial / physiopathology; Endocarditis, Bacterial / veterinary; Female; Male; Prognosis; Retrospective Studies; Treatment Outcome
TL;DR: In contrast to dogs, cats with IE typically present with clinical signs consistent with cardiac decompensation and locomotor abnormalities suggestive of either thromboembolic disease or inflammatory arthritis, and prognosis is grave. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Pyogranulomatous Pancarditis with Intramyocardial Bartonella henselae San Antonio 2 (BhSA2) in a Dog

Journal of Veterinary Internal Medicine, 31(1), 142–148.

By: T. Donovan*, P. Fox*, N. Balakrishnan n, M. Ericson*, V. Hooker* & E. Breitschwerdt n

author keywords: Canine; Myocarditis; Nephritis; Stealth; Vasculitis
MeSH headings : Animals; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Bartonella henselae / isolation & purification; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Endocarditis, Bacterial / veterinary; Female; Myocarditis / microbiology; Myocarditis / veterinary; Pericarditis / veterinary
TL;DR: A 6-year-old, female, spayed American Pitbull terrier was presented for progressive lethargy, weakness, and anorexia of 3-weeks duration, and found to have metabolic acidosis and Lyme quantitative C6 ELISA was negative. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Risk Factors for Bartonella species Infection in Blood Donors from Southeast Brazil

PLOS Neglected Tropical Diseases, 10(3), e0004509.

By: P. Diniz*, P. Velho*, L. Pitassi*, M. Drummond*, B. Lania*, M. Barjas-Castro*, S. Sowy*, E. Breitschwerdt n, D. Scorpio*

Ed(s): C. Budke

MeSH headings : Animals; Bacteremia; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / parasitology; Blood Donors / statistics & numerical data; Brazil / epidemiology; Cats; Cross-Sectional Studies; Female; Humans; Male; Occupational Exposure; Risk Factors; Zoonoses
TL;DR: These risk factors should be considered during donor screening, as bacteremia by these Bartonella species may not be detected by traditional laboratory screening methods, and it may be transmitted by blood transfusion. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Sarolaner—a novel isoxazoline—addresses the need for enhanced flea and tick control

Veterinary Parasitology, 222, 1–2.

By: E. Breitschwerdt*, S. Little & D. Rugg

MeSH headings : Animals; Ectoparasitic Infestations / prevention & control; Ectoparasitic Infestations / therapy; Ectoparasitic Infestations / veterinary; Isoxazoles / administration & dosage; Siphonaptera; Tick Control / standards; Ticks
Sources: Crossref, NC State University Libraries
Added: September 8, 2019

2016 journal article

Successful treatment of mitral valve endocarditis in a dog associated with 'Actinomyces canis-like' infection

JOURNAL OF VETERINARY CARDIOLOGY, 18(3), 271–277.

By: N. Balakrishnan n, K. Alexander n, B. Keene n, S. Kolluru n, M. Fauls n, I. Rawdon n, E. Breitschwerdt n

author keywords: Bacterial endocarditis; Blood culture; 16s rDNA PCR; Actinomycosis
MeSH headings : Actinomyces; Actinomycosis / veterinary; Animals; Dog Diseases / microbiology; Dogs; Echocardiography / veterinary; Endocarditis / microbiology; Endocarditis / veterinary; Heart Valve Diseases / microbiology; Heart Valve Diseases / veterinary; Male; Mitral Valve
TL;DR: A case of mitral valve endocarditis in a 9-year-old male-castrated Weimaraner caused by an Actinomyces canis-like bacterium, not previously reported in association with infection in dogs is reported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

Vasculitis, cerebral infarction and persistent Bartonella henselae infection in a child

Parasites & Vectors, 9(1).

By: N. Balakrishnan n, M. Ericson*, R. Maggi n & E. Breitschwerdt n

author keywords: Neurobartonellosis; Bartonella henselae San Antonio 2 vasculitis
MeSH headings : Bacteremia; Bartonella Infections / complications; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella henselae / genetics; Bartonella henselae / immunology; Bartonella henselae / isolation & purification; Brain / microbiology; Brain / pathology; Canada; Cerebral Infarction / diagnosis; Cerebral Infarction / etiology; Child; Female; Humans; Sequence Analysis, DNA; Vasculitis / complications; Vasculitis / diagnosis; Vasculitis / microbiology
TL;DR: B. henselae bacteremia, potentially spanning a 12-year time frame, in conjunction with the therapeutic administration of immunosuppressive drugs may have resulted in a progression and potentiation of the neurological disease that was partially reversible following antibiotic administration. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Vertical transmission of Anaplasma platys and Leishmania infantum in dogs during the first half of gestation

Parasites & Vectors, 9(1).

author keywords: Vertical transmission; Leishmania infantum; Anaplasma platys; Dog; Real-time PCR
MeSH headings : Anaplasma / genetics; Anaplasma / isolation & purification; Anaplasma / physiology; Anaplasmosis / parasitology; Anaplasmosis / transmission; Animals; Dog Diseases / microbiology; Dog Diseases / parasitology; Dog Diseases / transmission; Dogs; Female; Infectious Disease Transmission, Vertical / veterinary; Italy; Leishmania infantum / genetics; Leishmania infantum / immunology; Leishmania infantum / isolation & purification; Leishmania infantum / physiology; Leishmaniasis, Visceral / parasitology; Leishmaniasis, Visceral / transmission; Leishmaniasis, Visceral / veterinary; Ovary / microbiology; Ovary / parasitology; Pregnancy; Pregnancy Complications, Infectious / microbiology; Pregnancy Complications, Infectious / parasitology; Pregnancy Complications, Infectious / veterinary; Uterus / microbiology; Uterus / parasitology
TL;DR: Results from this study suggest that, in contrast to L. infantum, A. platys can be transmitted from pregnant dogs to their offspring during the first half of gestation, and this hypothesis remains to be verified, for instance via direct observation of parasites in postpartum foetal tissues. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

A putative marker for human pathogenic strains of Anaplasma phagocytophilum correlates with geography and host, but not human tropism

Ticks and Tick-Borne Diseases, 7(2), 390–393.

By: J. Foley*, N. Stephenson*, M. Cubilla*, B. Qurollo n & E. Breitschwerdt n

author keywords: Dog; Horse; Host-niche polymorphism; Ixodes pacificus; Tick-borne disease
MeSH headings : Anaplasma phagocytophilum / genetics; Anaplasma phagocytophilum / isolation & purification; Animals; Arachnid Vectors / microbiology; Biomarkers / metabolism; Dog Diseases / microbiology; Dogs; Ehrlichiosis / microbiology; Geography; Horse Diseases / microbiology; Horses; Host Specificity; Humans; Ixodes / microbiology; Membrane Proteins / genetics; Membrane Proteins / metabolism; Phylogeny; Sequence Analysis, DNA / veterinary; Tropism
TL;DR: Assessing 117 strains from 14 host species from across the US found thatPhylogenetic clades were associated with geography, but not host species, and a virulent clade that lacks drhm and infects dogs, horses, and humans in northeastern US was identified. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Bartonella henselaeas a cause of acute-onset febrile illness in cats

Journal of Feline Medicine and Surgery Open Reports, 1(2), 205511691560045.

By: E. Breitschwerdt n, J. Broadhurst & N. Cherry*

TL;DR: It is concluded that microbiological diagnosis and treatment of B henselae infection in cats can be challenging, that antibody titration results and resolution of clinical abnormalities may not correlate with a therapeutic cure, and that fever and potentially neutropenia should be differential diagnostic considerations for young cats with suspected bartonellosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 24, 2021

2015 journal article

Bartonella spp. Bacteremia in Blood Donors from Campinas, Brazil

PLOS Neglected Tropical Diseases, 9(1), e0003467.

By: L. Pitassi*, P. de Paiva Diniz*, D. Scorpio*, M. Drummond*, B. Lania*, M. Barjas-Castro*, R. Gilioli*, S. Colombo* ...

Ed(s): D. Walker

MeSH headings : Adult; Bacteremia / epidemiology; Bartonella Infections / epidemiology; Bartonella Infections / transmission; Bartonella henselae / genetics; Bartonella henselae / immunology; Bartonella henselae / isolation & purification; Blood Donors; Brazil / epidemiology; Cross-Sectional Studies; Female; Humans; Male; Polymerase Chain Reaction; Sequence Analysis, DNA
TL;DR: Bartonella species are blood-borne, re-emerging organisms, capable of causing prolonged infection with diverse disease manifestations, from asymptomatic bacteremia to chronic debilitating disease and death, and screening of blood supplies for this pathogen is not routinely performed. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Did Bartonella henselae contribute to the deaths of two veterinarians?

Parasites & Vectors, 8(1).

By: E. Breitschwerdt n

author keywords: Infection; Disease; Mortality; Cancer; Heart valve; Blood
MeSH headings : Aged; Animals; Bartonella Infections / etiology; Bartonella Infections / microbiology; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Bartonella henselae / physiology; Cat Diseases / microbiology; Cats; Fatal Outcome; Humans; Male; Middle Aged; Occupational Exposure / analysis; Veterinarians; Zoonoses / microbiology; Zoonoses / transmission
TL;DR: Bartonella henselae may or may not have been responsible for the deaths of two veterinarians, and recent evidence indicates that this genus is of much greater medical importance than is currently appreciated by the majority of the biomedical community. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Erratum to ‘Novel Bartonella infection in northern and southern sea otters (Enhydra lutris kenyoni and Enhydra lutris nereis)’

Erratum to ‘Novel Bartonella infection in northern and southern sea otters (Enhydra lutris kenyoni and Enhydra lutris nereis).’ Veterinary Microbiology, 181(3-4), 336.

By: S. Carrasco*, B. Chomel*, V. Gill*, R. Kasten*, R. Maggi n, E. Breitschwerdt n, B. Byrne*, K. Burek-Huntington ...

UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Infection with Bartonella henselae in a Danish Family

Journal of Clinical Microbiology, 53(5), 1556–1561.

By: R. Maggi n, N. Balakrishnan n, J. Bradley n & E. Breitschwerdt n

Ed(s): B. Fenwick

MeSH headings : Adolescent; Adult; Angiomatosis, Bacillary / diagnosis; Angiomatosis, Bacillary / microbiology; Angiomatosis, Bacillary / transmission; Bartonella henselae / classification; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Child; Family Health; Female; Genotype; Genotyping Techniques; Humans; Infant; Male; Middle Aged; Polymerase Chain Reaction; Sequence Analysis, DNA
TL;DR: Molecular microbiological evidence of Bartonella henselae genotype San Antonio 2 (SA2) infection in four of six Danish family members, including a child who died of unknown causes at 14 months of age is provided. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Naturally OccurringEhrlichia ewingiiandMycoplasmasp. Co-Infection in a Goat

Journal of Veterinary Internal Medicine, 29(6), 1735–1738.

By: K. Meichner n, B. Qurollo n, K. Anderson n, C. Grindem n, M. Savage n & E. Breitschwerdt n

author keywords: Caprine; Ehrlichiosis; Tick-borne disease
MeSH headings : Animals; Coinfection / microbiology; Coinfection / veterinary; Ehrlichia / isolation & purification; Ehrlichiosis / complications; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Female; Goat Diseases / microbiology; Goats; Mycoplasma / isolation & purification; Mycoplasma Infections / complications; Mycoplasma Infections / microbiology; Mycoplasma Infections / veterinary; Polymerase Chain Reaction; RNA, Bacterial / genetics; RNA, Ribosomal, 16S / genetics
TL;DR: A 9-year-old nonpregnant, nonlactating doe Boer goat was examined because of a 2-day history of not being able to stand and some degree of chronicity was considered likely. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Potentially Novel Ehrlichia Species in Horses, Nicaragua

Emerging Infectious Diseases, 21(2), 335–338.

By: V. O’Nion n, H. Montilla n, B. Qurollo n, R. Maggi n, B. Hegarty n, S. Tornquist n, E. Breitschwerdt n

MeSH headings : Animals; Ehrlichia / classification; Ehrlichia / genetics; Ehrlichiosis / veterinary; Horse Diseases / epidemiology; Horse Diseases / microbiology; Horses; Molecular Typing; Nicaragua / epidemiology; Phylogeny; RNA, Ribosomal, 16S / genetics; Serotyping
TL;DR: Sequencing of 16S rDNA, sodB, and groEL genes indicated that the bacterium is most likely a novel Ehrlichia species and the potential for canine and human infection remain unknown. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Prevalence of Bartonella spp. in Canine Cutaneous Histiocytoma

Journal of Comparative Pathology, 153(1), 14–21.

By: E. Pultorak n, K. Linder n, R. Maggi n, N. Balakrishnan n & E. Breitschwerdt n

author keywords: Bartonella; canine cutaneous histiocytoma; dog
MeSH headings : Animals; Bartonella Infections / complications; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Dog Diseases / microbiology; Dogs; Histiocytoma, Benign Fibrous / microbiology; Histiocytoma, Benign Fibrous / veterinary; Prevalence; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms / microbiology; Skin Neoplasms / veterinary
TL;DR: It is hypothesized that Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Serological and molecular analysis of feline vector-borne anaplasmosis and ehrlichiosis using species-specific peptides and PCR

Parasites & Vectors, 8(1), 320.

By: B. Hegarty n, B. Qurollo n, B. Thomas n, K. Park n, R. Chandrashekar*, M. Beall*, B. Thatcher*, E. Breitschwerdt n

author keywords: Anaplasma; Borrelia; Ehrlichia; Cats; Vector-borne pathogens
MeSH headings : Anaplasma / genetics; Anaplasma / immunology; Anaplasma / isolation & purification; Anaplasmosis / blood; Anaplasmosis / diagnosis; Anaplasmosis / microbiology; Animals; Antibodies, Bacterial / blood; Cat Diseases / blood; Cat Diseases / diagnosis; Cat Diseases / microbiology; Cats; Ehrlichia / genetics; Ehrlichia / immunology; Ehrlichia / isolation & purification; Ehrlichiosis / blood; Ehrlichiosis / diagnosis; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Female; Male; Peptides / genetics; Polymerase Chain Reaction; Prospective Studies; Species Specificity
TL;DR: This study provides the first evidence for E.chaffeensis and E.ewingii infection in naturally-exposed cats in North America and supports the need for regional, serological and molecular FVBP prevalence studies, and the need to further optimize serodiagnostic and PCR testing for cats. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Splenic vasculitis, thrombosis, and infarction in a febrile dog infected with Bartonella henselae

Journal of Veterinary Emergency and Critical Care, 25(6), 789–794.

By: S. Friedenberg*, N. Balakrishnan n, J. Guillaumin*, E. Cooper*, K. Lewis*, D. Russell*, E. Breitschwerdt n

author keywords: B. henselae; polyarthritis; splenic vasculitis; thrombosis
MeSH headings : Animals; Bartonella Infections / complications; Bartonella Infections / pathology; Bartonella Infections / veterinary; Bartonella henselae / genetics; DNA, Bacterial; Dog Diseases / etiology; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Female; Infarction / etiology; Infarction / veterinary; Spleen / blood supply; Splenic Diseases / microbiology; Splenic Diseases / pathology; Splenic Diseases / veterinary; Thrombosis / veterinary; Vasculitis / pathology; Vasculitis / veterinary
TL;DR: A potential role for this bacterium as a cause of vasculitis and thromboembolism, which have not been previously reported in association with B. henselae infection in dogs, is established. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

A serological survey of tick-borne pathogens in dogs in North America and the Caribbean as assessed by Anaplasma phagocytophilum, A. platys, Ehrlichia canis, E. chaffeensis, E. ewingii, and Borrelia burgdorferi species-specific peptides

Infection Ecology & Epidemiology, 4(1), 24699.

By: B. Qurollo n, R. Chandrashekar*, B. Hegarty n, M. Beall*, B. Stillman*, J. Liu*, B. Thatcher*, E. Pultorak n ...

TL;DR: This study demonstrated significant shifts in canine vector-borne disease seroprevalence rates, and the use of specific peptides facilitated improved geographic delineation of tick-borne pathogen distributions among dogs, which may enhance epidemiological surveillance ofvector-borne pathogens shared by dogs and humans. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 13, 2021

2014 journal article

Anaplasma platys in Bone Marrow Megakaryocytes of Young Dogs

Journal of Clinical Microbiology, 52(6), 2231–2234.

By: A. De Tommasi*, G. Baneth*, E. Breitschwerdt n, D. Stanneck*, F. Dantas-Torres*, D. Otranto*, D. de Caprariis*

MeSH headings : Anaplasma / isolation & purification; Anaplasmosis / microbiology; Anaplasmosis / pathology; Animals; Bone Marrow / microbiology; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Female; Male; Megakaryocytes / microbiology
TL;DR: Cellular inclusions were documented in bone marrow thrombocyte precursors of two young naturally infected dogs, indicating that A. platys can infect megakaryocytes and promegakaryocyte. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Bartonella clarridgeiae Bacteremia Detected in an Asymptomatic Blood Donor

Journal of Clinical Microbiology, 53(1), 352–356.

By: G. Vieira-Damiani*, P. Diniz*, L. Pitassi*, S. Sowy*, D. Scorpio*, B. Lania*, M. Drummond*, T. Soares* ...

Ed(s): K. Carroll

MeSH headings : Adult; Bacteriological Techniques / methods; Bartonella / genetics; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Blood Donors; Humans; Male; Polymerase Chain Reaction; Sequence Analysis, DNA
TL;DR: It is reported for the first time an asymptomatic human blood donor infected with B. clarridgeiae, as documented by enrichment blood culture, PCR, and DNA sequencing. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Bartonella henselae Infections In An Owner and Two Papillon Dogs Exposed to Tropical Rat Mites (Ornithonyssus bacoti)

Vector-Borne and Zoonotic Diseases, 14(10), 703–709.

By: J. Bradley n, P. Mascarelli n, C. Trull n, R. Maggi n & E. Breitschwerdt n

author keywords: Neuropsychiatric symptoms; Mites; Vector; Pruritis; Edema
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Antibodies, Bacterial / blood; Bartonella Infections / drug therapy; Bartonella Infections / microbiology; Bartonella Infections / transmission; Bartonella henselae / genetics; Bartonella henselae / immunology; Bartonella henselae / isolation & purification; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Doxycycline / therapeutic use; Female; Humans; Male; Mite Infestations / parasitology; Mites / microbiology; Polymerase Chain Reaction; Pruritus / drug therapy; Pruritus / microbiology; Pruritus / veterinary; Rats; Sequence Analysis, DNA; Zoonoses
TL;DR: Clinicians and vector biologists should consider the possibility that rat mites may play a role in Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Bartonella henselae and B. koehlerae DNA in Birds

Emerging Infectious Diseases, 20(3), 490–492.

By: P. Mascarelli n, M. McQuillan n, C. Harms n, R. Harms n & E. Breitschwerdt n

MeSH headings : Animals; Bartonella / classification; Bartonella / genetics; Bartonella Infections / veterinary; Bartonella henselae / classification; Bartonella henselae / genetics; Bird Diseases / microbiology; Bird Diseases / transmission; Birds; DNA, Bacterial; Disease Reservoirs / microbiology; Humans; Zoonoses / microbiology; Zoonoses / transmission
TL;DR: The substantial mobility, broad distribution, and migrations of birds make them ideal reservoir hosts for dispersal of infectious agents and the possibility that persistent blood-borne infection can occur in nonmammals and that the host range for Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 30, 2019

2014 journal article

Bartonellosis: One Health Perspectives for an Emerging Infectious Disease

ILAR Journal, 55(1), 46–58.

By: E. Breitschwerdt n

author keywords: animals; bacteria; Bartonella; bartonellosis; disease; One Health; reservoirs; vectors
MeSH headings : Animals; Arthropod Vectors / microbiology; Bartonella / genetics; Bartonella / pathogenicity; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Communicable Diseases, Emerging / epidemiology; Communicable Diseases, Emerging / veterinary; Humans; Research / trends; Species Specificity; Zoonoses / epidemiology
TL;DR: A One Health approach to bartonellosis and other zoonotic infections is needed to properly address animal health, public health, and environmental factors that influence the distribution and transmission of these bacteria. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Bilateral mandibular pyogranulomatous lymphadenitis and pulmonary nodules in a dog with Bartonella henselae bacteremia

Canadian Veterinary Journal, 55(10), 970–974.

By: M. Tucker, R. Sellon, R. Tucker, T. Wills, A. Simonsen, R. Maggi, E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Case Report: Molecular Evidence of Anaplasma platys Infection in Two Women from Venezuela

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 91(6), 1161–1165.

By: C. Arraga-Alvarado n, B. Qurollo n, O. Parra n, M. Berrueta n, B. Hegarty n & E. Breitschwerdt n

MeSH headings : Adult; Anaplasma / genetics; Anaplasmosis / diagnosis; Base Sequence; DNA Primers; DNA, Bacterial / genetics; Female; Humans; Middle Aged; Polymerase Chain Reaction; Venezuela
TL;DR: Two case reports of Anaplasma platys detection in two women from Venezuela are presented, providing further support for A. platys as a zoonotic tick-borne pathogen, most likely of low pathogenicity. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Co-infection with Anaplasma platys, Bartonella henselae, Bartonella koehlerae and ‘Candidatus Mycoplasma haemominutum’ in a cat diagnosed with splenic plasmacytosis and multiple myeloma

Journal of Feline Medicine and Surgery, 16(8), 713–720.

By: B. Qurollo n, N. Balakrishnan n, C. Cannon n, R. Maggi n & E. Breitschwerdt n

MeSH headings : Animals; Bartonella Infections / veterinary; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cats; Coinfection; Doxycycline / therapeutic use; Multiple Myeloma / diagnosis; Multiple Myeloma / drug therapy; Multiple Myeloma / veterinary; Mycoplasma Infections / drug therapy; Mycoplasma Infections / veterinary; Polymerase Chain Reaction / veterinary
TL;DR: Co-infection with multiple vector-borne pathogens should be a diagnostic consideration in cats with chronic hypergammaglobulinemia, monoclonal gammopathy and splenic plasmacytosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Comparison of serological and molecular panels for diagnosis of vector-borne diseases in dogs

Parasites & Vectors, 7(1), 127.

By: R. Maggi n, A. Birkenheuer n, B. Hegarty n, J. Bradley n, M. Levy n & E. Breitschwerdt n

author keywords: Canine vector-borne diseases; Serology; Molecular testing; Diagnostic panel
MeSH headings : Animals; Bacterial Infections / blood; Bacterial Infections / diagnosis; Bacterial Infections / microbiology; Bacterial Infections / veterinary; DNA, Bacterial / genetics; Dog Diseases / blood; Dog Diseases / diagnosis; Dogs; Parasitic Diseases, Animal / blood; Parasitic Diseases, Animal / diagnosis; Parasitic Diseases, Animal / parasitology; Serologic Tests / veterinary
TL;DR: Serological and PCR assays should be used in parallel to maximize CVBD diagnosis, and a panel combining serological and molecular assays run in parallel resulted in a 4-58% increase in the recognition of exposure to or infection with CVBD. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

ConcurrentBartonella henselaeinfection in a dog with panniculitis and owner with ulcerated nodular skin lesions

Veterinary Dermatology, 26(1), 60–e22.

By: M. Rossi, N. Balakrishnan n, K. Linder n, J. Messa* & E. Breitschwerdt n

MeSH headings : Aged; Angiomatosis, Bacillary / diagnosis; Angiomatosis, Bacillary / pathology; Angiomatosis, Bacillary / transmission; Angiomatosis, Bacillary / veterinary; Animals; Bartonella henselae; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dog Diseases / pathology; Dog Diseases / transmission; Dogs; Female; Humans; Male; Skin / pathology; Skin Ulcer / microbiology; Zoonoses / diagnosis; Zoonoses / microbiology; Zoonoses / pathology
TL;DR: B Bartonella henselae is an emerging zoonotic pathogen that induces granulomatous inflammatory lesions in various tissues of animals, including humans, and is concluded that this bacterium had a contributory or causative role in the development of the dermatological lesions in the dog and owner. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Detection of Bartonella Species in the Blood of Veterinarians and Veterinary Technicians: A Newly Recognized Occupational Hazard?

Vector-Borne and Zoonotic Diseases, 14(8), 563–570.

By: P. Lantos*, R. Maggi n, B. Ferguson*, J. Varkey*, L. Park*, E. Breitschwerdt n, C. Woods*

author keywords: Bartonella; Diagnostic test; Veterinarian; Zoonosis; Bacteremia
TL;DR: This study supports an emerging body of evidence that cryptic Bartonella bloodstream infection may be more frequent in humans than previously recognized and may induce symptoms. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Development and Validation of a Sensitive and Specific sodB-Based Quantitative PCR Assay for Molecular Detection of Ehrlichia Species

Journal of Clinical Microbiology, 52(11), 4030–4032.

By: B. Qurollo n, D. Riggins n, A. Comyn n, M. Zewde n & E. Breitschwerdt n

MeSH headings : Animals; Bacterial Proteins / genetics; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Dogs; Ehrlichia / genetics; Ehrlichia / isolation & purification; Ehrlichiosis / diagnosis; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Humans; Molecular Sequence Data; RNA, Ribosomal, 16S / genetics; Real-Time Polymerase Chain Reaction / methods; Sensitivity and Specificity; Sequence Analysis, DNA; Superoxide Dismutase / genetics
TL;DR: A sensitive and specific sodB-based quantitative PCR assay to detect Ehrlichia spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Evaluation of blood and bone marrow in selected canine vector-borne diseases

Parasites & Vectors, 7.

By: A. Tommasi*, D. Otranto*, T. Furlanello*, S. Tasca*, C. Cantacessi*, E. Breitschwerdt n, D. Stanneck*, F. Dantas-Torres* ...

Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2014 journal article

Evaluation of blood and bone marrow in selected canine vector-borne diseases

Parasites & Vectors, 7(1), 534.

By: A. De Tommasi*, D. Otranto*, T. Furlanello*, S. Tasca*, C. Cantacessi*, E. Breitschwerdt n, D. Stanneck*, F. Dantas-Torres* ...

author keywords: Bone marrow; Cytology; Vector-borne pathogens; Dysplasia; Secondary dysmyelopoiesis
MeSH headings : Animals; Bacterial Infections / pathology; Bacterial Infections / veterinary; Bone Marrow / pathology; Bone Marrow Cells; Disease Vectors; Dog Diseases / blood; Dog Diseases / parasitology; Dog Diseases / pathology; Dogs; Female; Male; Parasitic Diseases, Animal / pathology
TL;DR: The aim of the present study was to assess the pathological changes in canine BM associated with natural infections by four vector-borne pathogens, as well as to determine the relationships between such changes and abnormalities of the peripheral blood. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 13, 2021

2014 journal article

Experimental infection of cats with Afipia felis and various Bartonella species or subspecies

Veterinary Microbiology, 172(3-4), 505–510.

By: B. Chomel*, R. Kasten*, M. Stuckey*, E. Breitschwerdt n, R. Maggi n, J. Henn*, J. Koehler*, C. Chang*

author keywords: Bartonella; Afipia felis; Cats; Experimental infection; Zoonosis
MeSH headings : Afipia; Animals; Bacteremia / veterinary; Bartonella / classification; Bartonella / genetics; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Cat Diseases / microbiology; Cats; Gram-Negative Bacterial Infections / veterinary; Polymerase Chain Reaction
TL;DR: Most of the cats seroconverted, but only the cats inoculated with B. rochalimae became bacteremic, indicating that cats are not natural hosts of A. felis or the other Bartonella species or subspecies tested in this study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Guidelines for the diagnosis and antimicrobial therapy of canine superficial bacterial folliculitis (Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases)

Veterinary Dermatology, 25(3), 163–e43.

By: A. Hillier*, D. Lloyd*, J. Weese*, J. Blondeau*, D. Boothe*, E. Breitschwerdt n, L. Guardabassi*, M. Papich n ...

MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / therapeutic use; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dogs; Folliculitis / diagnosis; Folliculitis / drug therapy; Folliculitis / veterinary; Skin Diseases, Bacterial / diagnosis; Skin Diseases, Bacterial / drug therapy; Skin Diseases, Bacterial / veterinary
TL;DR: Optimal management of SBF will improve antimicrobial use and reduce selection of MRSP and other multidrug-resistant bacteria affecting animal and human health. (via Semantic Scholar)
Source: Crossref
Added: February 13, 2021

2014 review

Guidelines for the diagnosis and antimicrobial therapy of canine superficial bacterial folliculitis (Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases)

[Review of ]. Veterinary Dermatology, 25(3), 163-.

By: A. Hillier, D. Lloyd, J. Weese, J. Blondeau, D. Boothe, E. Breitschwerdt, L. Guardabassi, M. Papich ...

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Hemotropic mycoplasmas in little brown bats (Myotis lucifugus)

Parasites & Vectors, 7(1), 117.

By: P. Mascarelli n, M. Keel*, M. Yabsley*, L. Last*, E. Breitschwerdt n & R. Maggi n

author keywords: Hemotropic mycoplasma; Bat; Haemoplasma; Mycplasma; WNS
MeSH headings : Animals; Appalachian Region / epidemiology; Ascomycota / isolation & purification; Base Sequence; Chiroptera / microbiology; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Ribosomal / chemistry; DNA, Ribosomal / genetics; Disease Reservoirs; Molecular Sequence Data; Mycoplasma / classification; Mycoplasma / genetics; Mycoplasma / isolation & purification; Mycoplasma Infections / epidemiology; Mycoplasma Infections / microbiology; Mycoplasma Infections / mortality; Mycoplasma Infections / veterinary; Nose / pathology; Phylogeny; Polymerase Chain Reaction / veterinary; Prevalence; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA / veterinary; Spleen / pathology
TL;DR: Gene sequences generated from WNS and non-WNS animals suggest that little brown bats could serve as a natural reservoir for this potentially novel Mycoplasma species. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Hyperinsulinemic Hypoglycemia Syndrome in 2 Dogs with Bartonellosis

Journal of Veterinary Internal Medicine, 28(4), 1331–1335.

By: E. Breitschwerdt n, C. Goldkamp*, W. Castleman*, J. Cullen n, P. Mascarelli n, L. Thalhem n, M. Schaer*

author keywords: Dog; Hyperinsulinemia; Hypoglycemia; Monocytosis; Seizures
MeSH headings : Animals; Bartonella Infections / complications; Bartonella Infections / veterinary; Dog Diseases / microbiology; Dog Diseases / physiopathology; Dogs; Hyperinsulinism / etiology; Hyperinsulinism / veterinary; Hypoglycemia / etiology; Hypoglycemia / veterinary; Male; Syndrome
TL;DR: A 6-month-old male castrated, 21-kg Weimaraner developed seizures after surgical castration and umbilical hernia repair and was referred to NCSU-CVM-VTH for further evaluation. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

In Pursuit of a Stealth Pathogen: Laboratory Diagnosis of Bartonellosis

Clinical Microbiology Newsletter, 36(5), 33–39.

By: L. Wolf*, N. Cherry*, R. Maggi* & E. Breitschwerdt*

TL;DR: The evolution of culture techniques, serology, and nucleic acid amplification tests used to detect Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 6, 2020

2014 journal article

Incidence of Cercopithifilaria bainae in Dogs and Probability of Co-Infection with Other Tick-Borne Pathogens

PLOS ONE, 9(2).

MeSH headings : Anaplasma / genetics; Anaplasmosis / epidemiology; Anaplasmosis / parasitology; Animals; Babesia / genetics; Babesiosis / epidemiology; Babesiosis / parasitology; Babesiosis / veterinary; Coinfection; DNA, Protozoan / genetics; Dog Diseases / epidemiology; Dog Diseases / parasitology; Dog Diseases / transmission; Dogs; Ehrlichia canis / genetics; Ehrlichiosis / epidemiology; Ehrlichiosis / parasitology; Ehrlichiosis / veterinary; Female; Incidence; Italy / epidemiology; Male; Polymerase Chain Reaction; Rhipicephalus sanguineus / parasitology; Spirurida / physiology; Spirurida Infections / epidemiology; Spirurida Infections / transmission; Spirurida Infections / veterinary; Tick Infestations / epidemiology; Tick Infestations / transmission; Tick Infestations / veterinary
TL;DR: It is indicated that tick-infested dogs are at risk of acquiring infection by C. bainae and the detection of C.bainae microfilariae indicates a prior tick exposure and, should stimulate testing for other tick-borne disease causing pathogens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Intraoperative Bleeding in Dogs from Grenada Seroreactive to Anaplasma platys and Ehrlichia canis

Journal of Veterinary Internal Medicine, 28(6), 1702–1707.

By: M. Lanza-Perea*, U. Zieger*, B. Qurollo n, B. Hegarty n, E. Pultorak n, S. Kumthekar*, R. Bruhl-Day*, E. Breitschwerdt n

author keywords: Hemostasis; Infection; Rickettsia; Ticks
MeSH headings : Anaplasma; Anaplasmosis / blood; Anaplasmosis / complications; Anaplasmosis / epidemiology; Animals; Blood Loss, Surgical / veterinary; Dog Diseases / blood; Dog Diseases / epidemiology; Dog Diseases / etiology; Dog Diseases / microbiology; Dogs; Ehrlichia canis; Ehrlichiosis / blood; Ehrlichiosis / complications; Ehrlichiosis / epidemiology; Ehrlichiosis / veterinary; Female; Grenada / epidemiology; Male; Partial Thromboplastin Time / veterinary; Platelet Count / veterinary; Prothrombin Time / veterinary
TL;DR: Bleeding scores in dogs coseroreactive for A. platys and E. canis may have increased intraoperative bleeding tendencies despite normal hemostatic parameters, and improved tick control is needed for dogs in Grenada. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Intravascular persistence of Anaplasma platys, Ehrlichia chaffeensis, and Ehrlichia ewingii DNA in the blood of a dog and two family members

Parasites & Vectors, 7(1), 298.

By: E. Breitschwerdt n, B. Hegarty n, B. Qurollo n, T. Saito*, R. Maggi n, L. Blanton*, D. Bouyer*

author keywords: Anaplasma; Ehrlichia; Rickettsemia; PCR; DNA sequencing
MeSH headings : Adolescent; Anaplasma / isolation & purification; Anaplasmosis / blood; Anaplasmosis / microbiology; Animals; Dog Diseases / blood; Dog Diseases / microbiology; Dogs; Ehrlichia / isolation & purification; Ehrlichiosis / blood; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Female; Humans; Male; Middle Aged; Polymerase Chain Reaction; Serologic Tests
TL;DR: Serology and PCR targeting multiple microbial genes, followed by DNA sequencing, was used to test sequential blood samples and provided molecular evidence supporting intravascular persistence of A. platys and Ehrlichia spp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Molecular identification of Bartonella species in dogs with leishmaniosis (Leishmania infantum) with or without cytological evidence of arthritis

Veterinary Microbiology, 174(1-2), 272–275.

By: M. Mylonakis*, N. Soubasis*, N. Balakrishnan n, K. Theodorou, D. Kasabalis*, M. Saridomichelakis*, C. Koutinas*, A. Koutinas*, E. Breitschwerdt n

author keywords: Bartonella spp.; Leishmania infantum; Dog; Arthritis
MeSH headings : Animals; Arthritis / microbiology; Arthritis / pathology; Arthritis / veterinary; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Coinfection / microbiology; Coinfection / parasitology; Coinfection / veterinary; Culture Media; DNA Primers / genetics; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Leishmania infantum / isolation & purification; Leishmaniasis, Visceral / veterinary; Polymerase Chain Reaction / veterinary; Prevalence; Retrospective Studies
TL;DR: The primary objective of this study was to investigate the molecular prevalence of Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: February 13, 2021

2014 journal article

Novel Bartonella infection in northern and southern sea otters (Enhydra lutris kenyoni and Enhydra lutris nereis)

Veterinary Microbiology, 170(3-4), 325–334.

By: S. Carrasco*, B. Chomel*, V. Gill*, R. Kasten*, R. Maggi n, E. Breitschwerdt n, B. Byrne*, K. Burek-Huntington ...

author keywords: Bartonella; Streptococcus bovis/equinus; Vegetative valvular endocarditis; Northern sea otter; Southern sea otter; Enhydra lutris
MeSH headings : Alaska; Animals; Bartonella / classification; Bartonella / genetics; Bartonella Infections / complications; Bartonella Infections / microbiology; California; DNA, Bacterial / analysis; DNA, Ribosomal Spacer / genetics; Endocarditis / microbiology; Female; Genes, Bacterial / genetics; Heart Valves / microbiology; Hematologic Tests; Male; Molecular Sequence Data; Otters; Phylogeny; Risk Factors; Streptococcal Infections / complications
TL;DR: The study evaluated whether Streptococcus bovis/equinus (SB/E) and Bartonella infections were associated with UME-related disease characterized by VVE and septicemia in Alaskan sea otter carcasses recovered 2004-2008 and suggested that Bart onella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Performance of a commercially available in-clinic ELISA for detection of antibodies against Anaplasma phagocytophilum, Anaplasma platys, Borrelia burgdorferi, Ehrlichia canis, and Ehrlichia ewingii and Dirofilaria immiti santigen in dogs

Journal of the American Veterinary Medical Association, 245(1), 80–86.

By: B. Stillman*, M. Monn, J. Liu, B. Thatcher, P. Foster, B. Andrews, S. Little, M. Eberts ...

MeSH headings : Anaplasma / immunology; Anaplasmosis / blood; Anaplasmosis / diagnosis; Animals; Antibodies, Bacterial / blood; Antibodies, Helminth / blood; Borrelia burgdorferi / immunology; Dirofilaria immitis / immunology; Dirofilariasis / blood; Dirofilariasis / diagnosis; Dogs; Ehrlichia / immunology; Ehrlichiosis / blood; Ehrlichiosis / diagnosis; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay / methods; Enzyme-Linked Immunosorbent Assay / veterinary; Lyme Disease / blood; Lyme Disease / diagnosis; Lyme Disease / veterinary; Sensitivity and Specificity
TL;DR: Results of field evaluations confirmed that the in-clinic ELISA could be reliably used under typical clinical conditions to identify dogs exposed to the pathogens of interest. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Prostatitis, Steatitis, and Diarrhea in a Dog following Presumptive Flea-Borne Transmission of Bartonella henselae

Journal of Clinical Microbiology, 52(9), 3447–3452.

By: N. Balakrishnan n, J. Pritchard n, M. Ericson*, C. Grindem n, K. Phillips n, S. Jennings n, K. Mathews n, H. Tran* ...

Ed(s): E. Munson

MeSH headings : Animals; Bartonella Infections / complications; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Bartonella henselae / isolation & purification; Diarrhea / microbiology; Diarrhea / pathology; Diarrhea / veterinary; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Flea Infestations / complications; Flea Infestations / veterinary; Male; Prostatitis / diagnosis; Prostatitis / microbiology; Prostatitis / pathology; Steatitis / microbiology; Steatitis / pathology
TL;DR: A dog developed an unusual clinical presentation for canine bartonellosis following an acute flea infestation, and comprehensive medical, microbiological, and surgical interventions were required for diagnosis and to achieve a full recovery. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2014 journal article

Regional Seroreactivity and Vector-Borne Disease Co-Exposures in Dogs in the United States from 2004–2010: Utility of Canine Surveillance

Vector-Borne and Zoonotic Diseases, 14(10), 724–732.

By: C. Yancey*, B. Hegarty n, B. Qurollo n, M. Levy n, A. Birkenheuer n, D. Weber*, P. Diniz*, E. Breitschwerdt n

author keywords: Dirofilaria; Rickettsia; Babesia; Ehrlichia; United States; Anaplasma; Borrelia; Bartonella; Surveillance
MeSH headings : Anaplasma / immunology; Anaplasmosis / epidemiology; Animals; Arachnid Vectors / microbiology; Arachnid Vectors / parasitology; Babesia / immunology; Babesiosis / epidemiology; Bartonella / immunology; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Borrelia burgdorferi / immunology; Coinfection / veterinary; Dirofilaria immitis / immunology; Dirofilariasis / epidemiology; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dog Diseases / transmission; Dogs; Ehrlichia / immunology; Ehrlichiosis / epidemiology; Ehrlichiosis / veterinary; Lyme Disease / epidemiology; Retrospective Studies; Rickettsia / immunology; Rickettsia Infections / epidemiology; Rickettsia Infections / veterinary; Seroepidemiologic Studies; Tick-Borne Diseases / epidemiology; Tick-Borne Diseases / microbiology; Tick-Borne Diseases / parasitology; Tick-Borne Diseases / veterinary; Ticks / microbiology; Ticks / parasitology; United States / epidemiology
TL;DR: Notable annual and regional seroreactivity variation was observed with certain pathogens over 7 years of study, suggesting canine surveillance studies may have value in contributing to future VBD knowledge. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2014 journal article

Relationship Between Degenerative Joint Disease, Pain, and Bartonella spp. Seroreactivity in Domesticated Cats

Journal of Veterinary Internal Medicine, 29(1), 21–27.

By: A. Tomas n, E. Pultorak n, M. Gruen n, E. Breitschwerdt n & B. Lascelles n

MeSH headings : Animals; Antibodies, Bacterial / blood; Bartonella / isolation & purification; Bartonella Infections / immunology; Bartonella Infections / veterinary; Cat Diseases / blood; Cat Diseases / etiology; Cat Diseases / immunology; Cats; Female; Fluorescent Antibody Technique / veterinary; Male; Odds Ratio; Osteoarthritis / complications; Osteoarthritis / veterinary; Pain / etiology; Pain / veterinary; Risk Factors
TL;DR: Bartonella spp. (via Semantic Scholar)
Sources: NC State University Libraries, Crossref, NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Response to letter from J Mottet “Comments on the ISCAID Guidelines on the use of antimicrobial therapies in canine superficial bacterial folliculitis”

Response to letter from J Mottet “Comments on the ISCAID Guidelines on the use of antimicrobial therapies in canine superficial bacterial folliculitis.” Veterinary Dermatology, 25(6), 567–568.

By: D. Lloyd*, J. Weese*, J. Blondeau*, D. Boothe*, E. Breitschwerdt n, L. Guardabassi*, M. Papich n, S. Rankin* ...

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Dog Diseases / diagnosis; Folliculitis / veterinary; Skin Diseases, Bacterial / veterinary
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Serological and molecular prevalence of selected canine vector borne pathogens in blood donor candidates, clinically healthy volunteers, and stray dogs in North Carolina

Parasites & Vectors, 7(1), 116.

By: N. Balakrishnan, S. Musulin n, M. Varanat, J. Bradley & E. Breitschwerdt n

author keywords: Healthy dogs; CVBDs; Co-infection; Blood donors
MeSH headings : Animals; Bacterial Infections / blood; Bacterial Infections / epidemiology; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Blood Donors; Dog Diseases / blood; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Female; Insect Vectors; Male; North Carolina / epidemiology; Parasitic Diseases, Animal / blood; Parasitic Diseases, Animal / epidemiology; Prevalence; Seroepidemiologic Studies; Serologic Tests
TL;DR: To screen healthy dogs for serological and molecular evidence of regionally important CVBDs, serum and ethylenediamine tetraacetic acid anti-coagulated blood specimens collected from each dog were tested for CVBD pathogens. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Survey of veterinarians' perceptions of borreliosis in North Carolina

Journal of the American Veterinary Medical Association, 244(5), 592–596.

By: E. Pultorak n & E. Breitschwerdt n

MeSH headings : Animals; Arachnid Vectors / microbiology; Data Collection; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / prevention & control; Dogs; Lyme Disease / epidemiology; Lyme Disease / prevention & control; Lyme Disease / veterinary; Lyme Disease Vaccines / immunology; North Carolina / epidemiology; Tick Infestations / veterinary; Veterinarians
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Vector-borne pathogens in arctic foxes, Vulpes lagopus, from Canada

Research in Veterinary Science, 99, 58–59.

author keywords: Foxes; Canada; Vector-borne; Bartonella; Mycoplasma; Ehrlichia; Zoonosis
MeSH headings : Anaplasma / genetics; Animals; Babesia / genetics; Babesiosis / epidemiology; Bartonella / genetics; Canada / epidemiology; DNA, Bacterial / genetics; Ehrlichia / genetics; Foxes / blood; Foxes / microbiology; Gram-Negative Bacterial Infections / epidemiology; Mycoplasma / genetics; Polymerase Chain Reaction / veterinary; Prevalence
TL;DR: Preliminary evidence is provided that vector borne pathogens, not typically associated with the arctic ecosystem, exist at low levels in this arctic fox population, and that vector exposure, pathogen transmission dynamics, and changes in the geographic distribution of pathogens over time should be investigated in future studies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Zoonotic Bartonella Species in Cardiac Valves of Healthy Coyotes, California, USA

Emerging Infectious Diseases, 20(12), 2133–2136.

By: S. Kehoe*, B. Chomel, M. Stuckey*, R. Kasten*, N. Balakrishnan n, B. Sacks, E. Breitschwerdt n

MeSH headings : Animal Diseases / epidemiology; Animal Diseases / microbiology; Animals; Bartonella / classification; Bartonella / genetics; Bartonella Infections / veterinary; California / epidemiology; Coyotes / microbiology; DNA, Bacterial; Endocarditis, Bacterial / veterinary; Female; Genotype; Geography, Medical; Heart Valve Diseases / veterinary; Male; Zoonoses / epidemiology; Zoonoses / microbiology
TL;DR: Bartonella infection apparently leads to cardiac valve tropism, which could cause endocarditis, an often lethal complication in mammals, including humans. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

"Candidatus Mycoplasma haemomacaque" and Bartonella quintana Bacteremia in Cynomolgus Monkeys

Journal of Clinical Microbiology, 51(5), 1408–1411.

By: R. Maggi n, P. Mascarelli*, N. Balakrishnan n, C. Rohde*, C. Kelly*, L. Ramaiah*, M. Leach*, E. Breitschwerdt n

MeSH headings : Animals; Bacteremia / diagnosis; Bacteremia / microbiology; Bacteremia / veterinary; Bacterial Typing Techniques; Bartonella quintana / genetics; Base Sequence; Macaca fascicularis; Molecular Sequence Data; Monkey Diseases / diagnosis; Monkey Diseases / microbiology; Mycoplasma / classification; Mycoplasma / genetics; Mycoplasma / isolation & purification; Mycoplasma Infections / diagnosis; Mycoplasma Infections / microbiology; Mycoplasma Infections / veterinary; Phylogeny; RNA, Ribosomal, 16S / genetics; Ribonuclease P / genetics; Sequence Alignment; Sequence Analysis, DNA; Trench Fever / diagnosis; Trench Fever / veterinary
TL;DR: Sequence alignments, evolutionary analysis, and signature nucleotide sequence motifs of the hemotropic Mycoplasma 16S rRNA and RNase P genes indicate the presence of a novel organism. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

An unmatched case controlled study of clinicopathologic abnormalities in dogs with Bartonella infection

Comparative Immunology, Microbiology and Infectious Diseases, 36(5), 481–487.

By: C. Pérez Vera n, P. Diniz*, E. Pultorak n, R. Maggi n & E. Breitschwerdt n

author keywords: Bartonella; Dogs; BAPGM; Enrichment PCR; Hypoglobulinemia
MeSH headings : Animals; Bartonella / classification; Bartonella / genetics; Bartonella / pathogenicity; Bartonella Infections / immunology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Base Sequence; Blood Protein Disorders / veterinary; Case-Control Studies; DNA, Bacterial / genetics; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Female; Immunologic Deficiency Syndromes / veterinary; Male; Sequence Analysis, DNA; Weight Loss
TL;DR: With the exception of weight loss and hypoglobulinemia, clinicopathologic abnormalities in Bartonella-infected dogs in this study were similar to dogs suspected of other vector-borne infections. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Analysis of Seroreactivity against Cell Culture-DerivedBartonellaspp. Antigens in Dogs

Journal of Veterinary Internal Medicine, 28(1), 38–41.

By: B. Hegarty n, J. Bradley n, M. Lappin*, N. Balakrishnan n, P. Mascarelli n & E. Breitschwerdt n

author keywords: Bartonella henselae; Bartonella koehlerae; Bartonella vinsonii; Serodiagnostic limitations; Specificity
MeSH headings : Animals; Antibodies, Bacterial / blood; Antigens, Bacterial; Bacteremia / blood; Bacteremia / microbiology; Bacteremia / veterinary; Bartonella / isolation & purification; Bartonella Infections / blood; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Dog Diseases / blood; Dog Diseases / microbiology; Dogs; Fluorescent Antibody Technique, Indirect / standards; Fluorescent Antibody Technique, Indirect / veterinary; Sensitivity and Specificity; Specific Pathogen-Free Organisms
TL;DR: Serum from naïve SPF dogs shown to be negative for Bartonella bacteremia did not react with any of the 6 Bartoneella antigens by IFA testing. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Are vector-borne pathogen co-infections complicating the clinical presentation in dogs?

Parasites & Vectors, 6(1), 97.

By: A. De Tommasi*, D. Otranto*, F. Dantas-Torres*, G. Capelli*, E. Breitschwerdt n & D. de Caprariis*

author keywords: Co-infection; Dirofilaria immitis; Ehrlichia canis; Leishmania infantum; Bone marrow
MeSH headings : Animals; Blood / parasitology; Bone Marrow / parasitology; Bone Marrow / pathology; Coinfection / diagnosis; Coinfection / parasitology; Coinfection / pathology; Coinfection / veterinary; Dirofilaria immitis / isolation & purification; Dog Diseases / diagnosis; Dog Diseases / parasitology; Dog Diseases / pathology; Dogs; Ehrlichia canis / isolation & purification; Female; Italy; Leishmania infantum / isolation & purification; Male; Parasitic Diseases, Animal / diagnosis; Parasitic Diseases, Animal / parasitology; Parasitic Diseases, Animal / pathology
TL;DR: The clinical history and physical examination of findings for 7 CVBD co-infected dogs that were examined because of a spectrum of clinical signs and haematological abnormalities associated with the diagnostic evaluation and treatment of these dogs is described. (via Semantic Scholar)
Source: Crossref
Added: September 2, 2020

2013 journal article

Are vector-borne pathogen co-infections complicating the clinical presentation in dogs?

Parasites & Vectors, 6.

Edward Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Bartonella henselae bacteremia in a mother and son potentially associated with tick exposure

Parasites & Vectors, 6(1).

By: R. Maggi n, M. Ericson*, P. Mascarelli n, J. Bradley n & E. Breitschwerdt n

author keywords: Bartonella; BAPGM; Bacteremia; Striae; Neuropathy; Neurological disorder
MeSH headings : Adolescent; Animals; Antibodies, Bacterial / blood; Bacteremia / diagnosis; Bacteremia / microbiology; Bacteremia / pathology; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella henselae / isolation & purification; Female; Humans; Insect Bites and Stings / complications; Male; Middle Aged; Mothers; Netherlands; Nuclear Family
TL;DR: Preliminary evidence supporting the possibility of persistent B. henselae bacteremia in immunocompetent persons from Europe is provided. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Bartonella henselae infection in a family experiencing neurological and neurocognitive abnormalities after woodlouse hunter spider bites

Parasites & Vectors, 6(1), 98.

By: P. Mascarelli n, R. Maggi n, S. Hopkins*, B. Mozayeni*, C. Trull n, J. Bradley n, B. Hegarty n, E. Breitschwerdt n

author keywords: Bartonella; Spiders; Neurological disease; Guillain-Barre Syndrome; Serology; PCR
MeSH headings : Angiomatosis, Bacillary / complications; Angiomatosis, Bacillary / diagnosis; Animals; Bartonella henselae / isolation & purification; Child; Child, Preschool; Cognition Disorders / diagnosis; Cognition Disorders / etiology; Family Health; Female; Humans; Male; Spider Bites / complications; Spiders / microbiology
TL;DR: Although it was not possible to determine whether the family’s B. henselae infections were acquired by spider bites or whether the spiders and woodlice were merely accidental hosts, physicians should consider the possibility that B. Henselae represents an antecedent infection for GBS, CIDP, and non-specific neurocognitive abnormalities. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Co-infection with Anaplasma platys, Bartonella henselae and Candidatus Mycoplasma haematoparvum in a veterinarian

Parasites & Vectors, 6(1), 103.

By: R. Maggi n, P. Mascarelli n, L. Havenga*, V. Naidoo* & E. Breitschwerdt n

author keywords: Bartonella; Mycoplasma; Anaplasma; Headache; Migraines; Seizures; Serology; PCR
MeSH headings : Adult; Anaplasma / isolation & purification; Animals; Bacterial Infections / diagnosis; Bacterial Infections / microbiology; Bacterial Infections / pathology; Bacteriological Techniques; Bartonella henselae / isolation & purification; Coinfection / diagnosis; Coinfection / microbiology; Coinfection / pathology; Disease Vectors; Female; Grenada; Humans; Ireland; Mycoplasma / isolation & purification; Occupational Exposure; Polymerase Chain Reaction; Sequence Analysis, DNA; South Africa; Veterinarians
TL;DR: A 27-year-old female veterinarian experienced migraine headaches, seizures, including status epilepticus, and other neurological and neurocognitive abnormalities and no etiological diagnosis had been obtained to explain the patient's symptoms. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Comparative microbiological features of Bartonella henselae infection in a dog with fever of unknown origin and granulomatous lymphadenitis

Medical Microbiology and Immunology, 203(2), 85–91.

By: A. Drut*, I. Bublot*, E. Breitschwerdt n, L. Chabanne*, M. Vayssier-Taussat* & J. Cadoré*

author keywords: Bartonella henselae; Cat-scratch disease; Dog; Fever of unknown origin; Granulomatous lymphadenitis
MeSH headings : Angiomatosis, Bacillary / microbiology; Angiomatosis, Bacillary / veterinary; Animals; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; DNA, Bacterial / genetics; Dog Diseases / microbiology; Dogs; Female; Fever of Unknown Origin / microbiology; Fever of Unknown Origin / veterinary; Lymphadenitis / microbiology; Lymphadenitis / veterinary
TL;DR: The medical management of this case raises several clinically relevant comparative infectious disease issues, including the extent to which Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Efficacy of an imidacloprid/flumethrin collar against fleas, ticks and tick-borne pathogens in dogs

Parasites & Vectors, 6(1), 245.

By: F. Dantas-Torres*, G. Capelli*, A. Giannelli*, R. Ramos*, R. Lia*, C. Cantacessi*, D. de Caprariis*, A. De Tommasi* ...

author keywords: Canine vector-borne diseases; Anaplasma platys; Babesia vogeli; Hepatozoon canis; Prevention; Dog; Imidacloprid; Flumethrin; Tick
MeSH headings : Administration, Topical; Animals; Dog Diseases / prevention & control; Dogs; Female; Flea Infestations / prevention & control; Flea Infestations / veterinary; Imidazoles / administration & dosage; Insecticides / administration & dosage; Male; Neonicotinoids; Nitro Compounds / administration & dosage; Pyrethrins / administration & dosage; Tick Infestations / prevention & control; Tick Infestations / veterinary; Tick-Borne Diseases / prevention & control; Tick-Borne Diseases / veterinary; Treatment Outcome
TL;DR: This study demonstrates that the imidacloprid/flumethrin collar is efficacious against flea and tick infestation as well as tick-borne pathogen transmission to dogs under field conditions. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Evaluation of the role of tick-borne disease in 25 cases of high grade second degree or complete atrioventricular block in dogs

Journal of Veterinary Internal Medicine, 27(3), 642.

By: T. Hodge, T. DeFrancesco, M. Ames, J. Stern, S. Tou, C. Atkins, B. Keene, D. Trafny, M. Oyama, E. Breitschwerdt

Event: ACVIM Forum at Seattle, Washington on June 12-15, 2013

Source: NC State University Libraries
Added: March 7, 2021

2013 journal article

Experimental infection of dogs with Bartonella henselae and Bartonella vinsonii subsp. berkhoffii

Veterinary Immunology and Immunopathology, 156(1-2), 153–158.

By: N. Balakrishnan n, N. Cherry n, K. Linder n, E. Pierce n, N. Sontakke n, B. Hegarty n, J. Bradley n, R. Maggi n, E. Breitschwerdt n

author keywords: PCR; Bacteria; Bartonella henselae SA2; Bartonella vinsonii subsp berkhoffii genotype III; Isolation; Dog model
MeSH headings : Animals; Antibodies, Bacterial / blood; Bacteremia / immunology; Bacteremia / microbiology; Bacteremia / veterinary; Bartonella Infections / immunology; Bartonella Infections / microbiology; Bartonella henselae / immunology; DNA, Bacterial / analysis; Dog Diseases / immunology; Dog Diseases / microbiology; Dogs
TL;DR: Following intradermal infection, sequestration of Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Extrauterine Listeriosis in the Gravid Mouse Influences Embryonic Growth and Development

PLoS ONE, 8(8), e72601.

By: M. Suyemoto n, T. Hamrick n, P. Spears n, J. Horton n, I. Washington n, E. Havell n, L. Borst n, P. Orndorff n

Ed(s): R. Roop II

MeSH headings : Animals; Female; Listeria monocytogenes / physiology; Listeriosis / embryology; Mice; Placenta / embryology; Placenta / physiology; Pregnancy; Time Factors; Trophoblasts / cytology; Uterus / microbiology; Uterus / physiology
TL;DR: A model consistent with the authors' observations is one in which products (host or bacterial) generated during an acute infection enter embryos transplacentally and influences embryonic survival and slows normal growth in utero. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: July 20, 2019

2013 journal article

Flea species infesting dogs in Florida and Bartonella spp. prevalence rates

Veterinary Parasitology, 199(3-4), 225–229.

By: K. Yore, B. DiGangi*, M. Brewer, N. Balakrishnan n, E. Breitschwerdt n & M. Lappin

author keywords: Bartonella vinsonii subsp berkhoffii; Bartonella rochalimae; Bartonella clarridgeiae; Pulex spp.; Ctenocephalides felis
MeSH headings : Animals; Bartonella / classification; Bartonella / genetics; Bartonella / physiology; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; DNA, Bacterial / analysis; DNA, Bacterial / blood; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Flea Infestations / parasitology; Flea Infestations / veterinary; Florida / epidemiology; Genotype; Prevalence; Siphonaptera / microbiology
TL;DR: Evidence is provided that flea-infested dogs may be a reservoir host for Bvb and Br and that ectoparasite control is an important component of shelter intake protocols, and that Pulex fleas may beA vector for dogs and a source for zoonotic transfer of this pathogen from dogs to people. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

ID-13 Trends in Tick-Borne Disease Exposure in Dogs from the USA and Canada Determined by Species-Specific Peptide Assay

Journal of Veterinary Internal Medicine, 27(3), 724.

By: B. Qurollo, R. Chandrashekar, B. Hegarty, M. Beall, B. Stillman, J. Liu, B. Thatcher, B. Cerrito, M. Walsh, E. Breitschwerdt

Source: NC State University Libraries
Added: February 27, 2021

2013 journal article

Infection with Hemotropic Mycoplasma Species in Patients with or without Extensive Arthropod or Animal Contact

Journal of Clinical Microbiology, 51(10), 3237–3241.

By: R. Maggi n, S. Compton n, C. Trull n, P. Mascarelli n, B. Mozayeni & E. Breitschwerdt n

MeSH headings : Adult; Cohort Studies; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Ribosomal / chemistry; DNA, Ribosomal / genetics; Environmental Exposure; Female; Humans; Male; Middle Aged; Molecular Sequence Data; Mycoplasma / classification; Mycoplasma / genetics; Mycoplasma / isolation & purification; Mycoplasma Infections / epidemiology; Mycoplasma Infections / microbiology; Occupational Exposure; Prevalence; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA; Young Adult
TL;DR: The prevalence of hemotropic mycoplasma infection was significantly greater in previously reported cohorts of veterinarians, veterinary technicians, spouses of veterinary professionals, and others with extensive arthropod exposure and/or frequent animal contact than in a previously reported cohort of patients examined by a rheumatologist because of chronic joint pain or evidence of small-vessel disease. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Infection with Panola MountainEhrlichiasp. in a Dog with Atypical Lymphocytes and Clonal T-Cell Expansion

Journal of Veterinary Internal Medicine, 27(5), 1251–1255.

By: B. Qurollo n, A. Davenport n, B. Sherbert n, C. Grindem n, A. Birkenheuer n & E. Breitschwerdt n

author keywords: Lymphocytosis; Panola Mountain Ehrlichia sp.; Clonal T-cell expansion; Bacteria; Tick vector
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Dog Diseases / microbiology; Dogs; Doxycycline / therapeutic use; Ehrlichia / classification; Ehrlichiosis / blood; Ehrlichiosis / drug therapy; Ehrlichiosis / veterinary; Liver / cytology; Lymph Nodes / cytology; Lymphocytosis / veterinary; Male; T-Lymphocytes / classification; T-Lymphocytes / cytology; T-Lymphocytes / physiology; Thrombocytopenia / veterinary
TL;DR: An 11-year-old, castrated male Scottish Terrier that lived predominantly indoors and had no travel history was referred to the North Carolina State University Veterinary Health Complex in October 2012 for routine reevaluation of hepatobiliary disease and morphologic abnormalities raised the suspicion of possible lymphoid neoplasia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Koch's Postulates and the Pathogenesis of Comparative Infectious Disease Causation Associated with Bartonella species

Journal of Comparative Pathology, 148(2-3), 115–125.

By: E. Breitschwerdt n, K. Linder n, M. Day*, R. Maggi n, B. Chomel* & V. Kempf*

author keywords: disease; infection; pathology; Koch's postulates
TL;DR: Recent research observations involving the genus Bartonella are used to propose an additional postulate of comparative infectious disease causation to Koch's postulates. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Phylogenetic Diversity of Bacteria Isolated from Sick Dogs Using the BAPGM Enrichment Culture Platform

Journal of Veterinary Internal Medicine, 27(4), 854–861.

By: A. Davenport n, P. Mascarelli n, R. Maggi n & E. Breitschwerdt n

author keywords: Fastidious; Infection; Isolation; Sphingomonas
MeSH headings : Animals; Bacteria / classification; Bacteria / genetics; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Bacteriological Techniques / methods; DNA, Bacterial / genetics; Dog Diseases / microbiology; Dogs; Phylogeny; RNA, Ribosomal, 16S / genetics
TL;DR: Use of insect cell culture enrichment medium, such as BAPGM, appears to enhance the growth of alpha-Proteobacteria, but also results in isolation of non-alpha-Proteinobacteria from sick dogs, suggesting these organisms play a causal role in disease development. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Prevention of Canine Leishmaniosis in a Hyper-Endemic Area Using a Combination of 10% Imidacloprid/4.5% Flumethrin

PLOS ONE, 8(2).

By: D. Otranto*, F. Dantas-Torres*, D. Caprariis*, G. Di Paola*, V. Tarallo*, M. Latrofa*, R. Lia*, G. Annoscia* ...

MeSH headings : Animals; Dog Diseases / prevention & control; Dogs; Female; Imidazoles / therapeutic use; Leishmania infantum / pathogenicity; Leishmaniasis / prevention & control; Male; Neonicotinoids; Nitro Compounds / therapeutic use; Pyrethrins / therapeutic use
TL;DR: The use of collars containing 10% imidacloprid and 4.5% flumethrin conferred long-term protection against infection by L. infantum to dogs located in a hyper-endemic area, thus representing a reliable and sustainable strategy to decrease the frequency and spread of this disease among the canine population which will ultimately result in the reduction of associated risks to human health. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

Serial Testing from a 3-Day Collection Period by Use of the Bartonella Alphaproteobacteria Growth Medium Platform May Enhance the Sensitivity of Bartonella Species Detection in Bacteremic Human Patients

Journal of Clinical Microbiology, 51(6), 1673–1677.

By: E. Pultorak n, R. Maggi n, P. Mascarelli n & E. Breitschwerdt n

MeSH headings : Adult; Algorithms; Bacteremia / diagnosis; Bacteremia / microbiology; Bartonella / growth & development; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Blood / microbiology; Culture Media / chemistry; Female; Humans; Male; Middle Aged; Polymerase Chain Reaction / methods; Sensitivity and Specificity; Specimen Handling / methods; Time Factors
TL;DR: Obtaining three sequential blood samples during a 1-week period should be considered a diagnostic approach when bartonellosis is suspected. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Spontaneous onset of complex regional pain syndrome Type I in a woman infected with Bartonella koehlerae

Medical Microbiology and Immunology, 203(2), 101–107.

By: C. Vera n, R. Maggi n, C. Woods*, P. Mascarelli n & E. Breitschwerdt n

author keywords: Pain; Bacteria; Spider; Veterinarian; Neuropathogenesis
MeSH headings : Adult; Anti-Bacterial Agents / therapeutic use; Bartonella / drug effects; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / drug therapy; Bartonella Infections / microbiology; Complex Regional Pain Syndromes / drug therapy; Complex Regional Pain Syndromes / microbiology; Female; Humans
TL;DR: After a short-term fever, complex regional pain syndrome, characterized by hyperalgesia, intermittent swelling, erythema and cyanosis of both feet, was diagnosed in a female veterinarian and symptoms resolved following initiation of antibiotics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2013 journal article

Survey of Bartonella spp. in U.S. Bed Bugs Detects Burkholderia multivorans but Not Bartonella

PLoS ONE, 8(9), e73661.

By: V. Saenz n, R. Maggi n, E. Breitschwerdt n, J. Kim*, E. Vargo n & C. Schal n

Ed(s): S. Palli

MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; Bedbugs / microbiology; Burkholderia / genetics; Burkholderia / isolation & purification; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Intergenic / chemistry; DNA, Intergenic / genetics; Geography; Humans; Insect Vectors / microbiology; Molecular Sequence Data; Polymerase Chain Reaction; RNA, Ribosomal, 16S / genetics; RNA, Ribosomal, 23S / genetics; United States
TL;DR: This investigation investigated whether the resurgences of these medically important pathogens and their potential vector might be linked, by screening for Bartonella spp. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

2012 journal article

Bartonella bacteremia detected in non-lesional skin with laser scanning confocal microscopy

Journal of Investigative Dermatology, 132, S49.

By: P. Velho, E. Breitschwerdt, L. Henke, S. Nye, J. Nugent, S. Kavand, M. Ericson

Source: NC State University Libraries
Added: March 7, 2021

2012 journal article

Bartonella henselae infection in a man with hypergammaglobulinaemia, splenomegaly and polyclonal plasmacytosis

Journal of Medical Microbiology, 62(Pt_2), 338–341.

By: N. Balakrishnan n, J. Jawanda*, M. Miller* & E. Breitschwerdt n

MeSH headings : Aged; Bartonella Infections / complications; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella henselae / isolation & purification; Cat-Scratch Disease / diagnosis; Cat-Scratch Disease / microbiology; Humans; Hypergammaglobulinemia / complications; Male; Splenomegaly / complications
TL;DR: Clinicians should remain cognizant of the heterogeneous clinical presentations associated with bartonellosis. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Bartonella henselaeInfection Detected in Patients with Inflammatory Breast Cancer.

Cancer Research, 72(24 Supplement), P3–10-03.

By: S. Fernandez n, L. Aburto n, R. Maggi n, E. Breitschwerdt n & M. Cristofanilli n

Event: Poster Session at the Thirty-Fifth Annual CTRC‐AACR San Antonio Breast Cancer Symposium at San Antonio, TX on December 4-8, 2012

TL;DR: It is suggested that bacteria infections such as the one produced by Bartonella henselae might contribute to the clinical and pathological characteristics of IBC, associated with rapid spread of the breast tumor cells through the lymphatic system. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 13, 2021

2012 journal article

Bartonella spp. Bacteremia and Rheumatic Symptoms in Patients from Lyme Disease–endemic Region

Emerging Infectious Diseases, 18(11), 1919b–1921.

By: R. Maggi*, B. Mozayeni, E. Pultorak, B. Hegarty, J. Bradley, M. Correa, E. Breitschwerdt*

Sources: Crossref, NC State University Libraries
Added: February 13, 2021

2012 journal article

Bartonella vinsonii subsp. berkhoffii and Bartonella henselae as potential causes of proliferative vascular diseases in animals

Medical Microbiology and Immunology, 201(3), 319–326.

By: C. Beerlage*, M. Varanat n, K. Linder n, R. Maggi n, J. Cooley*, V. Kempf*, E. Breitschwerdt n

author keywords: Infection; Pathology; Systemic angiomatosis; Hemangiopericytoma; Bacteria
MeSH headings : Angiomatosis, Bacillary / microbiology; Angiomatosis, Bacillary / pathology; Angiomatosis, Bacillary / veterinary; Animals; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Bartonella henselae / classification; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Cat Diseases / microbiology; Cat Diseases / pathology; Cats; Cattle; Cattle Diseases / microbiology; Cattle Diseases / pathology; DNA, Bacterial / analysis; DNA, Bacterial / genetics; DNA, Bacterial / isolation & purification; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; HeLa Cells; Hemangiopericytoma / microbiology; Hemangiopericytoma / pathology; Hemangiopericytoma / veterinary; Humans; Polymerase Chain Reaction / methods
TL;DR: It is suggested that a fourth species, B. vinsonii subsp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Bartonellaspp. Bacteremia and Rheumatic Symptoms in Patients from Lyme Disease–endemic Region

Emerging Infectious Diseases, 18(5), 783–791.

By: R. Maggi n, B. Mozayeni n, E. Pultorak n, B. Hegarty n, J. Bradley n, M. Correa n, E. Breitschwerdt n

MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Arthritis / microbiology; Bacteremia / diagnosis; Bacteremia / epidemiology; Bacteremia / microbiology; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Child; Child, Preschool; Cross-Sectional Studies; Female; Humans; Lyme Disease / epidemiology; Male; Middle Aged; Molecular Typing; Serotyping; Surveys and Questionnaires; Young Adult
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Bartonellaspp. Infection in Healthy and Sick Horses and Foals from the Southeastern United States

Journal of Veterinary Internal Medicine, 26(6), 1408–1412.

By: N. Cherry n, S. Jones n, R. Maggi n, J. Davis n & E. Breitschwerdt n

author keywords: Bartonella vinsonii; coinfection; foals; lameness
MeSH headings : Animals; Antibodies, Bacterial; Bacteremia / blood; Bacteremia / veterinary; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Female; Fluorescent Antibody Technique, Indirect / veterinary; Horse Diseases / epidemiology; Horse Diseases / microbiology; Horses; Male; Polymerase Chain Reaction / veterinary; Serologic Tests; Southeastern United States
TL;DR: Horses in the southeastern United States are naturally infected with B. berkhofii genotypes I and III, and a bacteria most similar to Candidatus Bartonella volans, and further investigation into the pathogenic potential of Bart onella spp. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: September 9, 2019

2012 journal article

Candidatus Bartonella merieuxii, a Potential New Zoonotic Bartonella Species in Canids from Iraq

PLoS Neglected Tropical Diseases, 6(9), e1843.

By: B. Chomel*, A. McMillan-Cole*, R. Kasten*, M. Stuckey*, S. Sato*, S. Maruyama*, P. Diniz*, E. Breitschwerdt n

Ed(s): J. Vinetz

MeSH headings : Animals; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / veterinary; Cluster Analysis; DNA, Bacterial / blood; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Intergenic / chemistry; DNA, Intergenic / genetics; DNA-Directed RNA Polymerases / genetics; Dogs; Female; Foxes; Iraq; Jackals; Male; Molecular Sequence Data; Phylogeny; Sequence Analysis, DNA; Seroepidemiologic Studies
TL;DR: Seroprevalence in Iraqi dog owners and bacteremia in Iraqi people with unexplained fever or culture negative endocarditis requires further investigation as well as in United States military personnel who were stationed in Iraq. (via Semantic Scholar)
Source: Crossref
Added: February 20, 2021

2012 journal article

Candidatus Bartonella merieuxii, a potential new zoonotic Bartonella species in Canids from Iraq

PLoS Neglected Tropical Diseases, 6(9).

By: B. Chomel, K. A. C., S. R. W., S. M. J., M. S., D. S., . P. P. V. P., E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Candidatus Mycoplasma haematoparvum and Mycoplasma haemocanis infections in dogs from the United States

Comparative Immunology, Microbiology and Infectious Diseases, 35(6), 557–562.

By: S. Compton n, R. Maggi n & E. Breitschwerdt n

author keywords: Mycoplasma; Hemoplasmas; Erythrocytes; PCR; Disease
MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Female; Male; Mycoplasma / genetics; Mycoplasma / isolation & purification; Mycoplasma Infections / epidemiology; Mycoplasma Infections / microbiology; Mycoplasma Infections / veterinary; Phylogeny; Polymerase Chain Reaction / veterinary; Prevalence; RNA, Ribosomal, 16S / genetics; United States / epidemiology
TL;DR: The prevalence of Mhc and CMhp in this study was low; potential blood donors should be screened; and dogs and people can be co-infected with hemoplasma and Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Ehrlichia muris Infection in a Dog from Minnesota

Journal of Veterinary Internal Medicine, 26(5), 1217–1220.

By: B. Hegarty n, R. Maggi n, P. Koskinen*, M. Beall*, M. Eberts*, R. Chandrashekar*, E. Breitschwerdt n

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Ehrlichia / genetics; Ehrlichia / isolation & purification; Ehrlichiosis / drug therapy; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Male; Minnesota; Phylogeny; Polymerase Chain Reaction / veterinary; RNA, Ribosomal, 16S / chemistry; RNA, Ribosomal, 16S / genetics
TL;DR: A 6-year-old-male Labrador Retriever from northern Minnesota was examined by a veterinarian in June 2011 because of decreased activity, reluctance to climb stairs, and a history of having 2 attached ticks, but when re-examined in July, the dog had returned to normal activities and normal mobility. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Experimental Infection of Horses with Bartonella henselae and Bartonella bovis

Journal of Veterinary Internal Medicine, 26(2), 377–383.

By: J. Palmero*, N. Pusterla*, N. Cherry n, R. Kasten*, S. Mapes*, H. Boulouis*, E. Breitschwerdt n, B. Chomel*

author keywords: Animal model; Bacterial; Bacterial species; Bartonella; Bartonellosis; Epidemiology; Horse; Infectious diseases; Microbiology; Species Zoonoses
MeSH headings : Animals; Antibodies, Bacterial / blood; Bacteremia / immunology; Bacteremia / microbiology; Bacteremia / veterinary; Bartonella / genetics; Bartonella / immunology; Bartonella Infections / immunology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Female; Horse Diseases / immunology; Horse Diseases / microbiology; Horses; Male; Polymerase Chain Reaction / veterinary; Zoonoses / microbiology
TL;DR: Although mild clinical signs followed acute infection, no long-term effects were noted for 2 years postinoculation and detection of Bartonella sp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Failure to amplify bartonella koehlerae dna from blood of cats and their fleas in the united states

Journal of Veterinary Internal Medicine, 26(3), 791–792.

By: M. Lappin, R. Maggi, J. Hawley & E. Breitschwerdt

Event: ACVIM at New Orleans, LA on May 30 - June 2, 2012

Source: NC State University Libraries
Added: March 7, 2021

2012 journal article

Feline bartonellosis: we’re just scratching the surface

Journal of Feline Medicine and Surgery, 14(9), 609–610.

By: E. Breitschwerdt* & M. Lappin

MeSH headings : Animals; Bartonella Infections / transmission; Bartonella Infections / veterinary; Cat Diseases / transmission; Cats; Disease Vectors; Siphonaptera
TL;DR: A detailed, timely and comprehensive review of the current knowledge related to Bartonella species infection in cats, on which the authors, Dr Bianca Stützer and Professor Katrin Hartmann, are to be congratulated. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Granulomatous hepatitis due to Bartonella henselae infection in an immunocompetent patient

BMC Infectious Diseases, 12(1), 17.

By: T. VanderHeyden*, S. Yong*, E. Breitschwerdt n, R. Maggi n, A. Mihalik*, J. Parada*, C. Fimmel*

author keywords: Granulomatous hepatitis; Bartonella henselae; Diagnosis; Treatment
MeSH headings : Adult; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / surgery; Bartonella henselae / isolation & purification; Blood / microbiology; Female; Granuloma / microbiology; Granuloma / pathology; Hepatitis / diagnosis; Hepatitis / microbiology; Hepatitis / pathology; Hepatitis / surgery; Histocytochemistry; Humans; Liver / microbiology; Liver / pathology; Microscopy; Polymerase Chain Reaction; Radiography, Abdominal; Tomography, X-Ray Computed
TL;DR: The diagnosis of hepatic bartonellosis is exceedingly difficult to establish and requires a high degree of clinical suspicion, and recently developed, PCR-based approaches may be required in select patients to make the diagnosis. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 13, 2021

2012 journal article

Infection of human brain vascular pericytes (HBVPs) by Bartonella henselae

Medical Microbiology and Immunology, 202(2), 143–151.

By: M. Varanat n, R. Maggi n, K. Linder n & E. Breitschwerdt n

author keywords: Blood vessels; Bacteria; Cytokines; Vascular endothelial growth factor; Pericyte coverage
MeSH headings : Angiomatosis, Bacillary / metabolism; Angiomatosis, Bacillary / microbiology; Apoptosis; Bartonella henselae / physiology; Brain / metabolism; Brain / microbiology; Brain / pathology; Cell Proliferation; Cells, Cultured; Humans; Pericytes / metabolism; Pericytes / microbiology; Pericytes / ultrastructure; Vascular Endothelial Growth Factor A / biosynthesis
TL;DR: After infecting human brain vascular pericytes with Bartonella henselae, it was found that these bacteria were able to invade HBVPs and that bacterial infection resulted in decreased pericyte proliferation and increased pericyter production of vascular endothelial growth factor (VEGF) when compared to the uninfected control cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Isolation of a Novel Strain of Mycobacterium iranicum from a Woman in the United States

Journal of Clinical Microbiology, 51(2), 705–707.

By: N. Balakrishnan n, E. Tortoli*, S. Engel* & E. Breitschwerdt n

MeSH headings : Female; Genes, Bacterial; Humans; Lung / diagnostic imaging; Lung / pathology; Middle Aged; Mycobacterium / classification; Mycobacterium / genetics; Mycobacterium / isolation & purification; Mycobacterium Infections, Nontuberculous / diagnosis; Mycobacterium Infections, Nontuberculous / transmission; Radiography; Sputum / microbiology; United States
TL;DR: A novel strain of Mycobacterium iranicum, a recently described nontuberculous Myc Cobacterium species, was isolated from the sputum of a woman and fomite transmission of inhaled aerosolized secretions from her husband's sleep apnea equipment was historically possible. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Limited yield of diagnoses of intrahepatic infectious causes of canine granulomatous hepatitis from archival liver tissue

Journal of Veterinary Diagnostic Investigation, 24(5), 888–894.

By: R. Hutchins n, E. Breitschwerdt n, J. Cullen n, S. Bissett n & J. Gookin n

author keywords: Copper hepatopathy; dogs; fluorescent in situ hybridization; granulomatous hepatitis; polymerase chain reaction
MeSH headings : Animals; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Dog Diseases / diagnosis; Dog Diseases / pathology; Dogs; Female; Formaldehyde; Granuloma / pathology; Granuloma / veterinary; Hepatitis, Animal / diagnosis; Hepatitis, Animal / pathology; Liver / pathology; Male; Paraffin Embedding; Retrospective Studies; Tissue Preservation / veterinary
TL;DR: It was concluded that investigation of infectious etiologies within FFPE liver specimens using these diagnostic approaches may be of low yield. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Performance of the new in-clinic snap (R) 4dx (R) plus test for the detection of ehrlichia ewingii (granulocytic ehrlichiosis) and anaplasma platys (thrombocytotropic anaplasmosis) antibodies in dogs

Journal of Veterinary Internal Medicine, 26(3), 795–796.

By: B. Stillman, M. Beall, M. Monn & E. Breitschwerdt

Event: 2012 ACVIM Forum at New Orleans, LA on May 30 - June 2, 2012

Source: NC State University Libraries
Added: March 7, 2021

2012 journal article

Perinuclear antineutrophil cytoplasmic autoantibodies in dogs infected with various vector-borne pathogens and in dogs with immune-mediated hemolytic anemia

American Journal of Veterinary Research, 73(9), 1403–1409.

MeSH headings : Anemia, Hemolytic, Autoimmune / blood; Anemia, Hemolytic, Autoimmune / immunology; Anemia, Hemolytic, Autoimmune / veterinary; Animals; Antibodies, Antineutrophil Cytoplasmic / blood; Antibodies, Antineutrophil Cytoplasmic / immunology; Autoantibodies / blood; Autoantibodies / immunology; Chi-Square Distribution; Dog Diseases / blood; Dog Diseases / immunology; Dog Diseases / microbiology; Dogs; Female; Fluorescent Antibody Technique, Indirect / veterinary; Male; Prevalence; Retrospective Studies; Tick-Borne Diseases / immunology; Tick-Borne Diseases / microbiology; Tick-Borne Diseases / parasitology; Tick-Borne Diseases / veterinary
TL;DR: PANCA were detected in a high percentage of dogs with IMHA and vector-borne infectious diseases, therefore, pANCA may be a relatively nonspecific marker for dogs with inflammatory bowel disease, although they could represent a biomarker for immune-mediated diseases and infections. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Seroprevalence of Ehrlichia canis, Ehrlichia chaffeensis and Ehrlichia ewingii in dogs in North America

Parasites & Vectors, 5(1), 29.

By: M. Beall*, A. Alleman*, E. Breitschwerdt n, L. Cohn*, C. Couto*, M. Dryden*, L. Guptill*, C. Iazbik* ...

author keywords: Ehrlichia; E. canis; E. chaffeensis; E. ewingii; dog; tick; prevalence
MeSH headings : Animals; Antibodies, Bacterial / blood; Arachnid Vectors / microbiology; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dogs; Ehrlichia / immunology; Ehrlichia canis / immunology; Ehrlichia chaffeensis / immunology; Ehrlichiosis / diagnosis; Ehrlichiosis / epidemiology; Ehrlichiosis / veterinary; Humans; O Antigens; Peptides; Public Health; Seroepidemiologic Studies; Species Specificity; Ticks / microbiology; United States / epidemiology
TL;DR: The results of this study provide the first large scale regional documentation of exposure to E. canis, E. chaffeensis and E. ewingii in pet dogs, highlighting regional differences in seroprevalence and providing the basis for heightened awareness of these emerging vector-borne pathogens by veterinarians and public health agencies. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Serum cardiac troponin I concentrations in naturally occurring myelosuppressive and non-myelosuppressive canine monocytic ehrlichiosis

The Veterinary Journal, 194(2), 259–261.

By: C. Koutinas*, M. Mylonakis*, P. O’Brien*, L. Leontides*, V. Siarkou*, E. Breitschwerdt n, A. Koutinas*

author keywords: Canine monocytic ehrlichiosis; Heart; Cardiac troponin I; Ehrlichia canis; Prognosis
MeSH headings : Animals; Bone Marrow / pathology; Dog Diseases / blood; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Ehrlichia canis; Ehrlichiosis / blood; Ehrlichiosis / pathology; Ehrlichiosis / veterinary; Monocytes / pathology; Troponin I / blood
TL;DR: Serum cardiac troponin I (cTnI) concentration measured on admission was associated with the clinical severity of canine monocytic ehrlichiosis and was predictive of clinical outcome (death or survival) in dogs naturally infected with Ehrlichia canis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 journal article

Vector-Borne Diseases - constant challenge for practicing veterinarians: recommendations from the CVBD World Forum

Parasites & Vectors, 5(1), 55.

By: G. Baneth*, P. Bourdeau*, G. Bourdoiseau*, D. Bowman*, E. Breitschwerdt n, G. Capelli*, L. Cardoso*, F. Dantas-Torres* ...

MeSH headings : Animals; Bacterial Infections / diagnosis; Bacterial Infections / drug therapy; Bacterial Infections / prevention & control; Bacterial Infections / veterinary; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / prevention & control; Dogs; Parasitic Diseases, Animal / diagnosis; Parasitic Diseases, Animal / drug therapy; Parasitic Diseases, Animal / prevention & control; Veterinary Medicine / methods
TL;DR: Recommendations to veterinarians for the management of canine vector-borne diseases (CVBDs), a growing global threat as they continue their spread far from their traditional geographical and temporal restraints as a result of changes in both climatic conditions and pet dog travel patterns. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

"Candidatus Neoehrlichia mikurensis" Infection in a Dog from Germany

Journal of Clinical Microbiology, 49(5), 2059–2062.

By: P. Diniz*, B. Schulz*, K. Hartmann* & E. Breitschwerdt n

MeSH headings : Anaplasmataceae / isolation & purification; Anaplasmataceae Infections / complications; Anaplasmataceae Infections / diagnosis; Anaplasmataceae Infections / microbiology; Anaplasmataceae Infections / veterinary; Animals; Cluster Analysis; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Ribosomal / chemistry; DNA, Ribosomal / genetics; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Female; Germany; Molecular Sequence Data; Neutropenia / diagnosis; Phylogeny; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA
TL;DR: “Candidatus Neoehrlichia mikurensis” infection in a chronically neutropenic dog from Germany was confirmed by DNA sequencing by identifying a new intracellular pathogen associated with human infection and death. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

A case of granulomatous hepatitis due to bartonella henselae infection

American Journal of Gastroenterology, 106, S280.

By: T. VanderHeyden, C. Fimmel, E. Breitschwerdt, J. Parada, S. Yong & A. Mihalik

Source: NC State University Libraries
Added: March 12, 2021

2011 journal article

Antimicrobial Use Guidelines for Treatment of Urinary Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases

Veterinary Medicine International, 2011, 1–9.

By: J. Weese*, J. Blondeau*, D. Boothe*, E. Breitschwerdt n, L. Guardabassi*, A. Hillier*, D. Lloyd*, M. Papich n ...

Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: April 13, 2019

2011 journal article

Assessment of urine solute and matrix effects on the performance of an enzyme-linked immunosorbent assay for measurement of interleukin-6 in dog urine

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, 23(2), 316–320.

By: M. Wood n, S. Nordone n, S. Vaden n & E. Breitschwerdt n

author keywords: Cytokine; enzyme-linked immunosorbent assay; interleukin-6; matrix; urine
TL;DR: The role of urine pH, USG, and matrix are examined while optimizing a canine-specific chemiluminescent ELISA for the measurement of IL-6 in the urine of dogs to underscores the importance of critically optimizing testing modalities for biomarkers, particularly if they are immunologic in origin. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2011 journal article

Bartonella Species Bacteremia in Two Patients with Epithelioid Hemangioendothelioma

Journal of Clinical Microbiology, 49(11), 4006–4012.

By: P. Mascarelli n, J. Iredell*, R. Maggi n, G. Weinberg* & E. Breitschwerdt n

MeSH headings : Adult; Bacteremia / diagnosis; Bacteremia / microbiology; Bartonella / classification; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Female; Hemangioendothelioma, Epithelioid / complications; Hemangioendothelioma, Epithelioid / diagnosis; Humans; Male; Middle Aged
TL;DR: Chronic Bartonella infection could have a role in the development of this vascular neoplasm, considering the biology and clinically variable natural history of epithelioid hemangioendothelioma. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

Bartonella spp. DNA in Cardiac Tissues from Dogs in Colorado and Wyoming

Journal of Veterinary Internal Medicine, 25(3), 613–616.

By: A. Fenimore*, M. Varanat n, R. Maggi n, P. Schultheiss*, E. Breitschwerdt n & M. Lappin*

author keywords: Bartonella species; Blood cultures; Polymerase chain reaction assays
MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Colorado / epidemiology; DNA, Bacterial / isolation & purification; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Endocarditis, Bacterial / epidemiology; Endocarditis, Bacterial / microbiology; Endocarditis, Bacterial / veterinary; Retrospective Studies; Wyoming / epidemiology
TL;DR: The results emphasize the need for routine use of external parasite control products even in regions perceived to have low risk for flea and tick infestations and should be on the differential list for dogs in the Rocky Mountain states. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

Bartonella spp. bacteremia in high-risk immunocompetent patients

Diagnostic Microbiology and Infectious Disease, 71(4), 430–437.

By: R. Maggi n, P. Mascarelli n, E. Pultorak n, B. Hegarty n, J. Bradley n, B. Mozayeni, E. Breitschwerdt n

author keywords: Bartonella; BAPGM; Whole blood culture; Human; Isolation; PCR detection; IFA
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antibodies, Bacterial / blood; Bacteremia / diagnosis; Bacteremia / microbiology; Bacteremia / pathology; Bacteriological Techniques / methods; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bites and Stings / complications; Child; Female; Humans; Male; Middle Aged; Molecular Diagnostic Techniques / methods; Sensitivity and Specificity; Serologic Tests / methods; Skin / injuries; Young Adult
TL;DR: Serology, in conjunction with blood, serum, and BAPGM enrichment culture PCR, facilitates the diagnosis of Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 20, 2019

2011 journal article

Bartonella spp. in Feral Pigs, Southeastern United States

Emerging Infectious Diseases, 17(5), 893–895.

By: A. Beard n, R. Maggi n, S. Kennedy-Stoskopf n, N. Cherry n, M. Sandfoss n, C. DePerno n, E. Breitschwerdt n

MeSH headings : Animals; Bartonella / genetics; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; DNA, Ribosomal Spacer / genetics; Genes, Bacterial / genetics; Genotype; Male; Phylogeny; Sequence Homology; Southeastern United States / epidemiology; Swine; Swine Diseases / epidemiology; Swine Diseases / microbiology
TL;DR: In conjunction with efforts to assess pathogen exposure in feral pigs from the southeastern United States, amplified Bartonella henselae, B. koehlerae, and B. vinsonii subsp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2011 conference paper

Canine bartonellosis mimics other tick-borne diseases

Journal of Veterinary Internal Medicine, 25(3), 706–707.

By: C. Perez, P. Diniz, R. Maggi & E. Breitschwerdt

Event: American College Of Veterinary Internal Medicine Forum at Denver, Colorado on June 15-18, 2011

Source: NC State University Libraries
Added: March 12, 2021

2011 conference paper

Canine granulocytic anaplasmosis and granulocytic ehrlichiosis - a field-based comparison

Journal of Veterinary Internal Medicine, 25(3), 712.

By: M. Beall, B. Andrews, M. Eberts & E. Breitschwerdt

Event: American College of Veterinary Internal Medicine Forum at Denver, Colorado on June 15-18, 2011

Source: NC State University Libraries
Added: March 12, 2021

2011 journal article

Ecological Diversity ofBartonellaSpecies Infection Among Dogs and Their Owner in Virginia

Vector-Borne and Zoonotic Diseases, 11(11), 1425–1432.

By: N. Cherry n, R. Maggi n, J. Rossmeisl*, B. Hegarty n & E. Breitschwerdt n

author keywords: Bacteria; Disease; Ecology; Vector
MeSH headings : Animal Husbandry; Animals; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / transmission; Breeding; Databases, Nucleic Acid; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Ecology; Female; Genotype; Humans; Polymerase Chain Reaction; Virginia
TL;DR: Serology, serology, polymerase chain reaction, and enrichment blood culture were used to assess the prevalence of Bartonella sp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

Experimental infection by capillary tube feeding of Rhipicephalus sanguineus with Bartonella vinsonii subspecies berkhoffii

Comparative Immunology, Microbiology and Infectious Diseases, 35(1), 9–15.

By: S. Billeter*, R. Kasten*, L. Killmaster*, E. Breitschwerdt n, M. Levin*, M. Levy n, M. Kosoy*, B. Chomel*

author keywords: Bartonella vinsonii subspecies berkhoffii; Rhipicephalus sanguineus; Artificial infection; Transmission
MeSH headings : Animals; Arachnid Vectors / microbiology; Bacterial Typing Techniques; Bartonella / genetics; Bartonella / physiology; Bartonella Infections / microbiology; Bartonella Infections / transmission; Bartonella Infections / veterinary; DNA, Bacterial / genetics; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Feces / microbiology; Female; Polymerase Chain Reaction; Rabbits; Rhipicephalus sanguineus / microbiology
TL;DR: To determine whether adult R. sanguineus ticks can be infected with a B. v. berkhoffii genotype II isolate via capillary tube feeding and whether the infection can then be transmitted from adult females to their eggs via trans-ovarial transmission, tick fecal material was collected and screened as a possible source of infectious inoculum for canine infections. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

Fatal Aortic Endocarditis Associated with Community-Acquired Serratia marcescens Infection in a Dog

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 47(2), 133–137.

By: C. Perez n, Y. Fujii n, M. Fauls n, J. Hummel n & E. Breitschwerdt n

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Community-Acquired Infections / diagnosis; Community-Acquired Infections / drug therapy; Community-Acquired Infections / veterinary; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dogs; Endocarditis, Bacterial / diagnosis; Endocarditis, Bacterial / drug therapy; Endocarditis, Bacterial / veterinary; Fatal Outcome; Male; Serratia Infections / diagnosis; Serratia Infections / drug therapy; Serratia Infections / veterinary; Serratia marcescens
TL;DR: A 12 yr old Dalmatian was referred for evaluation of acute lethargy, fever, neurologic signs, and a recently ausculted heart murmur and found to have nonhospital-acquired Serratia marcescens bacteremia and aortic valve endocarditis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Hallucinations, Sensory Neuropathy, and Peripheral Visual Deficits in a Young Woman Infected with Bartonella koehlerae

Journal of Clinical Microbiology, 49(9), 3415–3417.

By: E. Breitschwerdt n, P. Mascarelli n, L. Schweickert, R. Maggi n, B. Hegarty n, J. Bradley n, C. Woods*

MeSH headings : Adolescent; Anti-Bacterial Agents / administration & dosage; Antibodies, Bacterial / blood; Bacteremia / diagnosis; Bacteremia / drug therapy; Bacteremia / microbiology; Bacteremia / physiopathology; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / drug therapy; Bartonella Infections / microbiology; Bartonella Infections / physiopathology; DNA, Bacterial / blood; Female; Hallucinations / diagnosis; Humans; Treatment Outcome
TL;DR: A young woman experiencing depression, anxiety, mood swings, severe headaches, muscle spasms, interphalangeal joint stiffness, decreased peripheral vision, diminished tactile sensation, and hallucinations was persistently Bartonella koehlerae seroreactive and bacteremic. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

Identification of Bartonella henselae in 2 Cats With Pyogranulomatous Myocarditis and Diaphragmatic Myositis

Veterinary Pathology, 49(4), 608–611.

By: M. Varanat n, J. Broadhurst, K. Linder n, R. Maggi n & E. Breitschwerdt n

author keywords: Bartonella; cats; diaphragmatic myositis; myocarditis
MeSH headings : Animals; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Bartonella henselae; Cat Diseases / microbiology; Cat Diseases / pathology; Cats; Fatal Outcome; Female; Male; Myocarditis / pathology; Myocarditis / veterinary; Myositis / pathology; Myositis / veterinary
TL;DR: This study supports a potential association between B. henselae and what has been historically described as “transmissible myocarditis and diaphragmitis” of undetermined cause in cats. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2011 journal article

Identification of Bartonella henselae in a horse from Germany

Veterinary Microbiology, 150(3-4), 414–415.

By: N. Cherry n, G. Liebisch, A. Liebisch, E. Breitschwerdt n, S. Jones n, R. Ulrich*, E. Allmers, P. Wolf*, M. Hewicker-Trautwein*

MeSH headings : Animals; Bartonella Infections / veterinary; Bartonella henselae / isolation & purification; Female; Germany; Horse Diseases / microbiology; Horses
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2011 journal article

Invasion of canine erythrocytes by Bartonella vinsonii subsp. berkhoffii

Veterinary Microbiology, 156(1-2), 213–216.

By: S. Billeter n, E. Breitschwerdt n & M. Levy n

author keywords: Bartonella vinsonii subsp berkhoffii; Erythrocyte; Canine; Invasion
MeSH headings : Animals; Bacteremia / microbiology; Bacteremia / veterinary; Bartonella / genetics; Bartonella / immunology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Dog Diseases / microbiology; Dogs; Female; Humans; Middle Aged
TL;DR: It is suggested that canine erythrocytes may serve in the maintenance of bacteremia due to B. vinsonii subsp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

2011 journal article

Molecular and Serological Diagnosis of Bartonella Infection in 61 Dogs from the United States

Journal of Veterinary Internal Medicine, 25(4), 805–810.

By: C. Pérez n, R. Maggi n, P. Diniz n & E. Breitschwerdt n

author keywords: Bacteria; BAPGM; Bartonella; Blood culture
MeSH headings : Animals; Antibodies, Bacterial / blood; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / blood; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Culture Media; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Fluorescent Antibody Technique, Indirect / veterinary; Logistic Models; Multivariate Analysis; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Retrospective Studies
TL;DR: Dogs were most often infected with B. henselae or B. berkhoffii based on PCR and enrichment culture, coinfection was documented, and various Bartonella species were identified. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

2011 journal article

Rickettsia rickettsii transmission by a lone star tick, North Carolina

Emerging Infectious Diseases, 17(5), 873–875.

By: E. Breitschwerdt, B. Hegarty, R. Maggi, P. Lantos, D. Aslett & J. Bradley

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Rickettsia rickettsiiTransmission by a Lone Star Tick, North Carolina

Emerging Infectious Diseases, 17(5), 873–875.

By: E. Breitschwerdt n, B. Hegarty n, R. Maggi n, P. Lantos n, D. Aslett n & J. Bradley n

MeSH headings : Adolescent; Animals; Bacterial Outer Membrane Proteins / genetics; Doxycycline / therapeutic use; Humans; Male; Mitochondria / genetics; North Carolina; RNA, Ribosomal, 16S / genetics; Rickettsia rickettsii / physiology; Rocky Mountain Spotted Fever / diagnosis; Rocky Mountain Spotted Fever / drug therapy; Rocky Mountain Spotted Fever / transmission; Skin / pathology; Ticks / genetics; Ticks / microbiology
TL;DR: Molecular evidence that A. americanum ticks can function, although most likely infrequently, as vectors of Rocky Mountain spotted fever for humans is provided. (via Semantic Scholar)
Source: Crossref
Added: January 24, 2021

2011 journal article

Seroprevalence of three ehrlichia species in dogs - a multi-institutional study

Journal of Veterinary Internal Medicine, 25(3), 748.

By: M. Beall, E. Breitschwerdt, L. Cohn, G. Couto, M. Dryden, S. Eddlestone, L. Guptill, W. Hoffman ...

Event: 2011 ACVIM Forum at Denver, Colorado on June 15-18, 2011

Source: NC State University Libraries
Added: March 7, 2021

2011 conference paper

The role of infectious agents in granulomatous hepatitis in dogs

Journal of Veterinary Internal Medicine, 25(3), 704.

By: R. Hutchins, E. Breitschwerdt, J. Cullen, S. Bissett & J. Gookin

Event: American College Of Veterinary Internal Medicine at Denver, Colorado on June 15-18, 2011

Source: NC State University Libraries
Added: March 12, 2021

2011 journal article

Typical and Atypical Manifestations of Anaplasma phagocytophilum Infection in Dogs

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 47(6), E86–E94.

By: M. Eberts n, P. Diniz n, M. Beall n, B. Stillman n, R. Chandrashekar n & E. Breitschwerdt n

MeSH headings : Anaplasma phagocytophilum / genetics; Anaplasma phagocytophilum / immunology; Anaplasma phagocytophilum / isolation & purification; Animals; Antibodies, Bacterial / immunology; DNA, Bacterial / analysis; Dog Diseases / epidemiology; Dog Diseases / etiology; Dog Diseases / pathology; Dogs; Ehrlichiosis / epidemiology; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Male; Minnesota / epidemiology; Polymerase Chain Reaction / veterinary; Retrospective Studies
TL;DR: Treatment with doxycycline resulted in rapid resolution of clinical signs in all dogs, and fever, arthropathy, neurologic dysfunction, and epistaxis are clinical syndromes that can be associated with A phagocytophilum infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2011 journal article

Vector-Borne Diseases in Client-Owned and Stray Cats from Madrid, Spain

Vector-Borne and Zoonotic Diseases, 12(2), 143–150.

author keywords: Cats; PCR; Serology; Vector-borne diseases
MeSH headings : Anaplasmataceae / immunology; Anaplasmataceae Infections / epidemiology; Anaplasmataceae Infections / veterinary; Animals; Antibodies, Bacterial / blood; Antibodies, Protozoan / blood; Bartonella / immunology; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Cat Diseases / epidemiology; Cat Diseases / microbiology; Cats; Disease Vectors; Female; Leishmania / immunology; Leishmaniasis / epidemiology; Leishmaniasis / veterinary; Male; Ownership; Polymerase Chain Reaction; Risk Factors; Spain / epidemiology
TL;DR: It is indicated that a large portion of the cat population of Madrid, Spain, is exposed to at least one of the five vector-borne pathogens tested, and about 9.9% of cats had antibody reactivity to more than one agent. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Autocrine Effects of Interleukin-6 Mediate Acute-Phase Proinflammatory and Tissue-Reparative Transcriptional Responses of Canine Bladder Mucosa

Infection and Immunity, 79(2), 708–715.

By: M. Wood n, E. Breitschwerdt n & J. Gookin n

Ed(s): A. Bäumler

MeSH headings : Acute-Phase Reaction / metabolism; Animals; Dogs; Humans; Interleukin-6 / metabolism; Mucous Membrane / metabolism; Mucous Membrane / microbiology; Signal Transduction; Tissue Culture Techniques; Urinary Bladder / metabolism; Urinary Bladder / microbiology; Uropathogenic Escherichia coli; Urothelium / metabolism
TL;DR: It is demonstrated that uropathogenic Escherichia coli infection stimulates the synthesis of IL-6 by all urothelial cell layers, with the u rothelial cells alone representing the only site of unequivocal IL- 6 receptor expression. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Bacillary angiomatosis in an immunosuppressed dog

Veterinary Dermatology, 21(4), 420–428.

By: J. Yager*, S. Best, R. Maggi n, M. Varanat n, N. Znajda* & E. Breitschwerdt n

MeSH headings : Angiomatosis, Bacillary / drug therapy; Angiomatosis, Bacillary / immunology; Angiomatosis, Bacillary / veterinary; Animals; Anti-Bacterial Agents / therapeutic use; Azathioprine / therapeutic use; Azithromycin / therapeutic use; Clindamycin / therapeutic use; Dogs; Female; Immunocompromised Host; Immunosuppressive Agents / adverse effects; Immunosuppressive Agents / therapeutic use; Pancytopenia / drug therapy; Pancytopenia / veterinary; Prednisone / therapeutic use
TL;DR: A dog being treated with immunosuppressive doses of prednisone and azathioprine for pancytopenia of unknown origin, developed, over a 2-week period, multiple erythematous nodular lesions in the skin including footpads identical to those of human bacillary angiomatosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2010 journal article

Bartonella vinsonii subsp. berkhoffii and Bartonella henselae bacteremia in a father and daughter with neurological disease

Parasites & Vectors, 3(1), 29.

By: E. Breitschwerdt n, R. Maggi n, P. Lantos*, C. Woods*, B. Hegarty n & J. Bradley n

TL;DR: Intravascular infection with B. berkhoffii and B. henselae are zoonotic pathogens that can be isolated from the blood of immunocompetent family members with arthralgias, fatigue and neurological symptoms and may also pose a risk to human beings. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2010 journal article

Bartonellosis: an emerging infectious disease of zoonotic importance to animals and human beings

Journal of Veterinary Emergency and Critical Care, 20(1), 8–30.

By: E. Breitschwerdt n, R. Maggi n, B. Chomel* & M. Lappin n

author keywords: bacteria; cat; diagnosis; disease; dog
MeSH headings : Animals; Animals, Domestic / microbiology; Animals, Wild / microbiology; Bartonella Infections / epidemiology; Bartonella Infections / transmission; Bartonella Infections / veterinary; Cats; Communicable Diseases, Emerging / epidemiology; Communicable Diseases, Emerging / veterinary; Disease Reservoirs / microbiology; Disease Reservoirs / veterinary; Dogs; Humans; Occupational Diseases / epidemiology; Occupational Diseases / microbiology; Occupational Diseases / veterinary; Species Specificity; Zoonoses
TL;DR: A review of clinically relevant observations related to Bartonella species as emerging pathogens in veterinary and human medicine to provide a review of clinical relevant observations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Diagnosis of Canine Vector-Borne Diseases in Young Dogs: a Longitudinal Study

Journal of Clinical Microbiology, 48(9), 3316–3324.

By: D. Otranto, G. Testini, F. Dantas-Torres, M. Latrofa, P. Diniz*, D. de Caprariis, R. Lia, N. Mencke* ...

MeSH headings : Anaplasma / genetics; Anaplasma / isolation & purification; Anaplasmosis / diagnosis; Animals; Antibodies, Protozoan / blood; Babesia / genetics; Babesia / isolation & purification; Babesiosis / diagnosis; Babesiosis / veterinary; Disease Vectors; Dog Diseases / diagnosis; Dogs; Ehrlichia canis / genetics; Ehrlichia canis / isolation & purification; Ehrlichiosis / diagnosis; Ehrlichiosis / veterinary; Insect Vectors; Italy; Leishmania infantum / immunology; Leishmania infantum / isolation & purification; Leishmaniasis, Visceral / diagnosis; Leishmaniasis, Visceral / veterinary; Longitudinal Studies; Polymerase Chain Reaction
TL;DR: Insight is provided on the incidence of certain pathogens infecting young dogs in southern Italy, important diagnostic testing limitations are highlighted, and the use of multiple diagnostic modalities when attempting to confirm a tick-borne infection in an individual dog or in a canine population is supported. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 conference paper

Diversity of bartonella species in 62 dogs using the bapgm pre-enrichment culture method

Journal of Veterinary Internal Medicine, 24(3), 759.

By: C. Perez, P. Diniz, R. Maggi & E. Breitschwerdt

Event: 2010 American College of Veterinary Internal Medicine Forum at Anaheim, CA on June 9-12, 2010

Source: NC State University Libraries
Added: March 16, 2021

2010 journal article

Evaluation of Brain Tissue or Cerebrospinal Fluid with Broadly Reactive Polymerase Chain Reaction for Ehrlichia, Anaplasma, Spotted Fever Group Rickettsia, Bartonella, and Borrelia Species in Canine Neurological Diseases (109 Cases)

Journal of Veterinary Internal Medicine, 24(2), 372–378.

By: R. Barber*, Q. Li*, P. Diniz*, B. Porter*, E. Breitschwerdt n, M. Claiborne*, A. Birkenheuer n, J. Levine* ...

author keywords: Central nervous system (CNS); Inflammation; Meningoencephalomyelitis; Vector-borne microorganisms
MeSH headings : Animals; Brain / microbiology; DNA, Bacterial / classification; DNA, Bacterial / isolation & purification; Dog Diseases / cerebrospinal fluid; Dog Diseases / microbiology; Dogs; Female; Gram-Negative Bacteria / isolation & purification; Gram-Negative Bacterial Infections / cerebrospinal fluid; Gram-Negative Bacterial Infections / microbiology; Gram-Negative Bacterial Infections / veterinary; Male; Meningoencephalitis / microbiology; Meningoencephalitis / veterinary; Polymerase Chain Reaction / veterinary
TL;DR: The results of this investigation suggest that microorganisms in the genera Ehrlichia, Anaplasma, Rickettsia, Bartonella, and Borrelia are unlikely to be directly associated with canine MEM in the geographic regions evaluated. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2010 journal article

Evaluation of peptide- and recombinant protein-based assays for detection of anti-Ehrlichia ewingii antibodies in experimentally and naturally infected dogs

American Journal of Veterinary Research, 71(10), 1195–1200.

By: T. O'Connor*, J. Saucier, D. Daniluk, B. Stillman, R. Krah, Y. Rikihisa, Q. Xiong, M. Yabsley ...

MeSH headings : Animals; Antibodies, Bacterial / blood; Dog Diseases / blood; Dog Diseases / epidemiology; Dog Diseases / immunology; Dogs; Ehrlichia / immunology; Ehrlichiosis / blood; Ehrlichiosis / diagnosis; Ehrlichiosis / epidemiology; Ehrlichiosis / immunology; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay / methods; Enzyme-Linked Immunosorbent Assay / veterinary; False Positive Reactions; Immunoassay / methods; Immunoassay / veterinary; Missouri / epidemiology; Peptides; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Recombinant Proteins
TL;DR: The EESP and EETp28 ELISAs were suitable for specifically detecting anti-E ewingii antibodies in experimentally and naturally infected dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Evolution of clinical, haematological and biochemical findings in young dogs naturally infected by vector-borne pathogens

Veterinary Microbiology, 149(1-2), 206–212.

By: D. de Caprariis*, F. Dantas-Torres*, G. Capelli*, N. Mencke*, D. Stanneck*, E. Breitschwerdt n, D. Otranto*

author keywords: Vector-borne diseases; Clinical signs; Haematological alterations; Diagnosis
MeSH headings : Anaplasma / pathogenicity; Animals; Babesia / pathogenicity; Bartonella / pathogenicity; Coccidia / pathogenicity; Disease Vectors; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Ehrlichia canis / pathogenicity; Gram-Negative Bacterial Infections / drug therapy; Imidazoles / pharmacology; Longitudinal Studies; Male; Neonicotinoids; Nitro Compounds / pharmacology; Permethrin / pharmacology; Polymerase Chain Reaction / veterinary; Protozoan Infections, Animal / drug therapy; Siphonaptera / microbiology; Thrombocytopenia; Ticks / microbiology
TL;DR: This study emphasizes the clinical difficulties associated with assigning a specific clinical sign or haematological abnormality to a particular canine vector-borne disease and serially monitored naturally infected dogs throughout a 1-year follow-up period. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Experimental infection and co-infection of dogs with Anaplasma platys and Ehrlichia canis: hematologic, serologic and molecular findings

Parasites & Vectors, 3(1), 33.

By: S. Gaunt*, M. Beall*, B. Stillman*, L. Lorentzen*, P. Diniz*, R. Chandrashekar*, E. Breitschwerdt n

TL;DR: The results of this study demonstrate that simultaneous or sequential infection with A. platys and E. canis can alter various pathophysiological parameters in experimentally infected dogs, and because natural exposure to multiple tick-borne pathogens occurs frequently in dogs, awareness of co-infection is important in clinical practice. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Feline immunodeficiency virus, feline leukemia virus and Bartonella species in stray cats on St Kitts, West Indies

Journal of Feline Medicine and Surgery, 12(6), 435–440.

By: P. Kelly*, L. Moura*, T. Miller*, J. Thurk*, N. Perreault*, A. Weil n, R. Maggio n, H. Lucas*, E. Breitschwerdt n

MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella henselae / isolation & purification; Cat Diseases / epidemiology; Cat Diseases / microbiology; Cats; DNA Primers; Databases, Nucleic Acid; Female; Immunodeficiency Virus, Feline / isolation & purification; Lentivirus Infections / epidemiology; Lentivirus Infections / veterinary; Lentivirus Infections / virology; Leukemia Virus, Feline / isolation & purification; Male; Polymerase Chain Reaction / veterinary; Prevalence; Retroviridae Infections / epidemiology; Retroviridae Infections / veterinary; Retroviridae Infections / virology; Saint Kitts and Nevis / epidemiology; Schools, Veterinary; Tumor Virus Infections / epidemiology; Tumor Virus Infections / veterinary; Tumor Virus Infections / virology
TL;DR: Stray cats trapped in various areas of Basseterre, the capital of St Kitts in the West Indies, were tested for infection with feline immunodeficiency virus (FIV) and feline leukemia virus (FeLV) using commercial kits, revealing DNA of Bartonella species in whole blood collected from 60/95 cats traps in 2006/7. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2010 journal article

Flea-associated zoonotic diseases of cats in the USA: bartonellosis, flea-borne rickettsioses, and plague

Trends in Parasitology, 26(4), 197–204.

By: K. McElroy*, B. Blagburn*, E. Breitschwerdt n, P. Mead* & J. McQuiston*

MeSH headings : Animals; Bartonella Infections / epidemiology; Bartonella Infections / transmission; Bartonella Infections / veterinary; Cat Diseases / epidemiology; Cat Diseases / transmission; Cat-Scratch Disease / epidemiology; Cat-Scratch Disease / transmission; Cat-Scratch Disease / veterinary; Cats; Humans; Insect Vectors / microbiology; Plague / epidemiology; Plague / transmission; Plague / veterinary; Rickettsia Infections / epidemiology; Rickettsia Infections / transmission; Rickettsia Infections / veterinary; Siphonaptera / microbiology; United States / epidemiology; Zoonoses / epidemiology; Zoonoses / microbiology; Zoonoses / transmission
TL;DR: Understanding flea-borne pathogens, and the associated risks for owners and veterinarians, is important to reduce the likelihood of zoonotic infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Human Coinfection with Bartonella henselae and Two Hemotropic Mycoplasma Variants Resembling Mycoplasma ovis

Journal of Clinical Microbiology, 48(10), 3782–3785.

By: J. Sykes*, L. Lindsay*, R. Maggi n & E. Breitschwerdt n

MeSH headings : Anti-Bacterial Agents / therapeutic use; Bacteriological Techniques / methods; Bartonella henselae / isolation & purification; Blood / microbiology; Cat-Scratch Disease / complications; Cat-Scratch Disease / diagnosis; Cat-Scratch Disease / drug therapy; Cat-Scratch Disease / microbiology; DNA, Bacterial / blood; Humans; Male; Middle Aged; Mycoplasma / isolation & purification; Mycoplasma Infections / complications; Mycoplasma Infections / diagnosis; Mycoplasma Infections / drug therapy; Mycoplasma Infections / microbiology; Polymerase Chain Reaction / methods; Texas; Treatment Outcome; Veterinarians
TL;DR: Two variants of an organism resembling the ovine hemoplasma, Mycoplasma ovis, were detected by PCR in blood samples from a veterinarian in Texas, marking the first report of human infection with this organism. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 conference paper

Immunologic testing of dog urine requires neutralization of matrix effects to allow for accurate measurement of il-6 concentrations

Journal of Veterinary Internal Medicine, 24(3), 770.

By: M. Wood, E. Breitschwerdt, S. Vaden & S. Nordone

Event: American College Of Veterinary Internal Medicine at Anaheim, CA on June 9-12, 2010

Source: NC State University Libraries
Added: March 12, 2021

2010 journal article

Leishmaniasis in a dog native to Colorado

Journal of the American Veterinary Medical Association, 237(11), 1288–1291.

By: K. Freeman n, M. Miller n, E. Breitschwerdt n & M. Lappin n

MeSH headings : Animals; Antibodies, Protozoan / blood; Colorado / epidemiology; Dog Diseases / blood; Dog Diseases / epidemiology; Dog Diseases / parasitology; Dogs; Female; Infectious Disease Transmission, Vertical; Leishmania infantum / isolation & purification; Leishmaniasis, Visceral / blood; Leishmaniasis, Visceral / epidemiology; Leishmaniasis, Visceral / veterinary; Male
TL;DR: This dog was from a litter of 10 puppies that included 4 stillborn puppies, 2 puppies that died as neonates, and 1 littermate that was euthanized at 1 year of age because of a high serum antibody titer against Leishmania spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Molecular Evidence of Perinatal Transmission of Bartonella vinsonii subsp. berkhoffii and Bartonella henselae to a Child

Journal of Clinical Microbiology, 48(6), 2289–2293.

By: E. Breitschwerdt n, R. Maggi n, P. Farmer n & P. Mascarelli n

MeSH headings : Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / microbiology; Bartonella Infections / transmission; Blood / microbiology; Brain / microbiology; Cervix Uteri / microbiology; Child; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Bacterial / isolation & purification; Family Health; Female; Humans; Infectious Disease Transmission, Vertical; Liver / microbiology; Male; Middle Aged; Molecular Sequence Data; Placenta / microbiology; Polymerase Chain Reaction; Pregnancy; Pregnancy Complications, Infectious / microbiology; Sequence Analysis, DNA; Spleen / microbiology
TL;DR: DNA of both organisms was amplified and sequenced from blood, enrichment blood cultures, or autopsy tissues from four family members and historical and microbiological results support perinatal transmission of Bartonella species in this family. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

PCR amplification of Bartonella koehlerae from human blood and enrichment blood cultures

Parasites & Vectors, 3(1), 76.

By: E. Breitschwerdt n, R. Maggi n, B. Robert Mozayeni, B. Hegarty n, J. Bradley n & P. Mascarelli n

TL;DR: The results of this study suggest that B. koehlerae bacteremia is more common in immunocompetent people than has been previously suspected. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2010 conference paper

Performance comparison of species-specific peptide-based assays with immunofluorescence assays for detection of canine antibodies to anaplasma and ehrlichia spp

Journal of Veterinary Internal Medicine, 24(3), 765–766.

By: B. Stillman, M. Beall, P. Shields, B. Hegarty, E. Breitschwerdt & R. Chandrashekar

Event: 2010 American College of Veterinary Internal Medicine Forum at Anaheim, CA

Source: NC State University Libraries
Added: March 16, 2021

2010 journal article

Performance of a commercially available in-clinic ELISA for the detection of antibodies against Anaplasma phagocytophilum, Ehrlichia canis, and Borrelia burgdorferi and Dirofilaria immitis antigen in dogs

American Journal of Veterinary Research, 71(12), 1443–1450.

By: R. Chandrashekar*, C. Mainville, M. Beall, T. O'Connor, M. Eberts, A. Alleman, S. Gaunt, E. Breitschwerdt*

MeSH headings : Anaplasma phagocytophilum / immunology; Animals; Antibodies, Bacterial / blood; Antibodies, Bacterial / immunology; Antibodies, Helminth / blood; Antibodies, Helminth / immunology; Borrelia burgdorferi / immunology; Dirofilaria immitis / immunology; Dirofilariasis / immunology; Dog Diseases / blood; Dog Diseases / immunology; Dogs; Ehrlichia canis / immunology; Ehrlichiosis / immunology; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay / methods; Enzyme-Linked Immunosorbent Assay / veterinary; Lyme Disease / immunology; Lyme Disease / veterinary; Tick-Borne Diseases / immunology; Tick-Borne Diseases / veterinary
TL;DR: The commercially available in-clinic ELISA could be used by veterinarians to screen dogs for heartworm infection and for exposure to tick-borne pathogens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: February 20, 2021

2010 journal article

Potential for Tick-borne Bartonelloses

Emerging Infectious Diseases, 16(3), 385–391.

MeSH headings : Animals; Arachnid Vectors / classification; Arachnid Vectors / microbiology; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / transmission; DNA, Bacterial / analysis; Humans; Species Specificity; Ticks / classification; Ticks / microbiology
TL;DR: There is little evidence that Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: NC State University Libraries, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Prevalence of Bartonella henselae and Borrelia burgdorferi Sensu Lato DNA in Ixodes ricinus Ticks in Europe

Applied and Environmental Microbiology, 76(5), 1395–1398.

By: F. Dietrich*, T. Schmidgen*, R. Maggi n, D. Richter*, F. Matuschka*, R. Vonthein*, E. Breitschwerdt n, V. Kempf*

MeSH headings : Animals; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Borrelia burgdorferi Group / genetics; Borrelia burgdorferi Group / isolation & purification; DNA, Bacterial / isolation & purification; France; Germany; Ixodes / microbiology; Nymph / microbiology; Portugal; Prevalence
TL;DR: The data indicate that ticks might serve as a vector for the transmission of B. henselae to humans and Borrelia burgdorferi sensu lato, the pathogen most frequently transmitted by ticks. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Prevalence of Selected Vector-borne Organisms and Identification of Bartonella Species DNA in North American River Otters (Lontra canadensis)

Journal of Wildlife Diseases, 46(3), 947–950.

By: S. Chinnadurai n, A. Birkenheuer n, H. Blanton n, R. Maggi n, N. Belfiore*, H. Marr n, E. Breitschwerdt n, M. Stoskopf n

author keywords: Bartonella; disease; Ehrlichia; Lontra canadensis; Ricketisia; river otter
MeSH headings : Animals; Animals, Wild / microbiology; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / transmission; Bartonella Infections / veterinary; DNA, Bacterial / blood; Female; Male; North Carolina / epidemiology; Otters / virology; Polymerase Chain Reaction / veterinary; Prevalence; Rivers
TL;DR: Trapper-killed North American river otters in North Carolina, USA, were screened for multiple vector-borne bacteria known to be pathogenic to mammals and blood from one live otter captured in 2008 was found positive for this Bartonella sp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2010 journal article

Prevention of endemic canine vector-borne diseases using imidacloprid 10% and permethrin 50% in young dogs: A longitudinal field study

Veterinary Parasitology, 172(3-4), 323–332.

By: D. Otranto*, D. de Caprariis*, R. Lia*, V. Tarallo*, V. Lorusso*, G. Testini*, F. Dantas-Torres*, S. Latrofa* ...

author keywords: Canine vector-borne diseases; Anaplasma platys; Babesia; Ehrlichia canis; Hepatozoon canis; Leishmania infantum; Prevention; Imidacloprid; Permethrin
MeSH headings : Animals; Disease Vectors; Dog Diseases / epidemiology; Dog Diseases / parasitology; Dog Diseases / prevention & control; Dogs; Female; Imidazoles; Incidence; Insecticides; Longitudinal Studies; Male; Neonicotinoids; Nitro Compounds; Permethrin; Tick-Borne Diseases / epidemiology; Tick-Borne Diseases / parasitology; Tick-Borne Diseases / veterinary
TL;DR: It is demonstrated that ImPer preventive treatment against arthropods protects autochthonous and naïve beagle dogs against CVBD-causing pathogens and reduces overall CVBD incidence density rate in dogs treated with ImPer. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Severe Hepatitis Associated with Acute Ehrlichia canis Infection in a Dog

Journal of Veterinary Internal Medicine, 24(3), 633–638.

By: M. Mylonakis*, M. Kritsepi-Konstantinou*, J. Dumler*, P. Diniz*, M. Day*, V. Siarkou*, E. Breitschwerdt n, V. Psychas* ...

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Dogs; Doxycycline / therapeutic use; Ehrlichia canis; Ehrlichiosis / complications; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Hepatitis, Animal / etiology; Hepatitis, Animal / microbiology; Male
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

Successful treatment ofBartonella henselaeendocarditis in a cat

Journal of Feline Medicine and Surgery, 12(6), 483–486.

By: C. Perez n, J. Hummel n, B. Keene n, R. Maggi n, P. Diniz n & E. Breitschwerdt n

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bartonella Infections / diagnosis; Bartonella Infections / drug therapy; Bartonella Infections / veterinary; Bartonella henselae / isolation & purification; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cat Diseases / microbiology; Cats; Endocarditis, Bacterial / diagnosis; Endocarditis, Bacterial / drug therapy; Endocarditis, Bacterial / microbiology; Endocarditis, Bacterial / veterinary; Fluorescent Antibody Technique, Indirect / veterinary; Male; Treatment Outcome
TL;DR: In conjunction with previous case reports, infective endocarditis can be associated with natural B henselae infection in cats; however, early diagnosis and treatment may result in a better prognosis than previously reported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: NC State University Libraries, NC State University Libraries, Crossref
Added: August 6, 2018

2010 conference paper

Survival of bartonella henselae in the blood of cats used for transfusion

Journal of Veterinary Internal Medicine, 24(3), 759.

By: C. Bradbury, M. Green, M. Brewer, E. Breitschwerdt & M. Lappin

Event: 2010 American College of Veterinary Internal Medicine Forum at Anaheim, CA on June 9-12, 2010

Source: NC State University Libraries
Added: March 16, 2021

2010 journal article

Suspected Needle Stick Transmission of Bartonella vinsonii subspecies berkhoffii to a Veterinarian

Journal of Veterinary Internal Medicine, 24(5), 1229–1232.

By: A. Oliveira n, R. Maggi n, C. Woods* & E. Breitschwerdt n

MeSH headings : Adult; Animals; Bartonella / classification; Bartonella / isolation & purification; Bartonella Infections / transmission; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Humans; Male; Needlestick Injuries; Veterinarians; Zoonoses / microbiology; Zoonoses / transmission
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2010 journal article

The increasing recognition of rickettsial pathogens in dogs and people

Trends in Parasitology, 26(4), 205–212.

By: W. Nicholson*, K. Allen*, J. McQuiston*, E. Breitschwerdt n & S. Little*

MeSH headings : Animals; Arachnid Vectors / microbiology; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Humans; Public Health; Rickettsia Infections / epidemiology; Rickettsia Infections / microbiology; Rickettsia Infections / transmission; Rickettsia Infections / veterinary; Tick Infestations / epidemiology; Tick Infestations / microbiology; Tick Infestations / transmission; Tick Infestations / veterinary; Tick-Borne Diseases / epidemiology; Tick-Borne Diseases / microbiology; Tick-Borne Diseases / transmission; Tick-Borne Diseases / veterinary; Ticks / microbiology; United States / epidemiology; Zoonoses
TL;DR: The ecology and epidemiology of tick-borne bacterial pathogens in the order Rickettsiales, including Ehrlichia and Rickettsia species, are highlighted, and avenues for future investigation are proposed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

A Groundhog, a Novel Bartonella Sequence, and My Father's Death

Emerging Infectious Diseases, 15(12), 2080–2086.

By: E. Breitschwerdt n, R. Maggi, M. Cadenas & P. Vissotto de Paiva Diniz

MeSH headings : Aged; Aged, 80 and over; Animals; Bartonella Infections / etiology; Humans; Male; Marmota / microbiology
TL;DR: During the summer of 2007, migratory joint pain developed in my 86-year-old father, previously an ironworker, farmer, and World War II veteran; because of occasional tick attachments, a Borrelia burgdorferi ELISA was performed; antibodies were not detected, and no treatment was instituted. (via Semantic Scholar)
Source: Crossref
Added: September 2, 2020

2009 conference paper

A confusing case of canine vector-borne disease: clinical signs and progression in a dog co-infected with Ehrlichia canis and Bartonella vinsonii ssp berkhoffii

Parasites & Vectors, 2.

By: E. Breitschwerdt & R. Maggi

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

A confusing case of canine vector-borne disease: clinical signs and progression in a dog co-infected with Ehrlichia canis and Bartonella vinsonii ssp. berkhoffii

Parasites & Vectors, 2(Suppl 1), S3.

By: E. Breitschwerdt n & R. Maggi n

TL;DR: The authors discuss the seemingly diverse spectrum of disease manifestations, the co-infections of Bartonellosis spp. (via Semantic Scholar)
Source: Crossref
Added: September 1, 2020

2009 journal article

A groundhog, a novel bartonella sequence, and my father's death

Emerging Infectious Diseases, 15(12), 2080–2086.

By: E. Breitschwerdt, R. Maggi, M. Cadenas & P. Diniz

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Bartonella Endocarditis

Annals of the New York Academy of Sciences, 1166(1), 120–126.

By: B. Chomel, R. Kasten, C. Williams*, A. Wey*, J. Henn, R. Maggi n, S. Carrasco*, J. Mazet* ...

author keywords: Bartonella; endocarditis; dogs; cats; cattle; reservoir
MeSH headings : Animals; Animals, Wild / microbiology; Bartonella / pathogenicity; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / transmission; Cat Diseases / microbiology; Cat Diseases / pathology; Cat Diseases / transmission; Cats; Cattle; Cattle Diseases / microbiology; Cattle Diseases / transmission; Disease Reservoirs; Dog Diseases / microbiology; Dog Diseases / pathology; Dog Diseases / transmission; Dogs; Endocarditis / microbiology; Female; Heart / microbiology; Humans; Male; Myocardium / pathology; Zoonoses / epidemiology; Zoonoses / microbiology; Zoonoses / transmission
TL;DR: The clinical and pathological characteristics of Bartonella endocarditis in dogs are similar to disease observed in humans, more often affecting the aortic valve, presenting with highly vegetative lesions with accompanying calcification, and in most instances high antibody titers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 13, 2021

2009 conference paper

Bartonella endocarditis: A pathology shared by animal reservoirs and patients

Rickettsiology and rickettsial diseases, 1166, 120–126.

By: B. Chomel, R. Kasten, C. Williams, A. Wey, J. Henn, R. Maggi, S. Carrasco, J. Mazet ...

Source: NC State University Libraries
Added: August 6, 2018

2009 article

Clinical Relevance of Annual Screening Using a Commercial Enzyme-Linked Immunosorbent Assay (SNAP 3Dx) for Canine Ehrlichiosis

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, Vol. 45, pp. 118–124.

By: B. Hegarty n, P. Diniz n, J. Bradley n, L. Lorentzen n & E. Breitschwerdt n

MeSH headings : Animals; Diagnosis, Differential; Diagnostic Tests, Routine / methods; Diagnostic Tests, Routine / standards; Diagnostic Tests, Routine / veterinary; Dog Diseases / blood; Dog Diseases / diagnosis; Dogs; Ehrlichia / genetics; Ehrlichia / immunology; Ehrlichia / isolation & purification; Ehrlichiosis / blood; Ehrlichiosis / diagnosis; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay / standards; Enzyme-Linked Immunosorbent Assay / veterinary; Fluorescent Antibody Technique / standards; Fluorescent Antibody Technique / veterinary; Polymerase Chain Reaction / standards; Polymerase Chain Reaction / veterinary; Thrombocytopenia / blood; United States
TL;DR: In this study, thrombocytopenia was frequently detected in healthy Ehrlichia SNAP 3Dx-positive dogs, whereas active infection was infrequently confirmed by PCR, and treatment based upon screening results alone is not recommended. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2009 journal article

Co-isolation of Bartonella henselae and Bartonella vinsonii subsp. berkhoffii from blood, joint and subcutaneous seroma fluids from two naturally infected dogs

Veterinary Microbiology, 138(3-4), 368–372.

By: P. Diniz n, M. Wood n, R. Maggi n, S. Sontakke n, M. Stepnik n & E. Breitschwerdt n

author keywords: Alpha Proteobacteria; Culture; Arthritis; Seroma; Co-infection; Bartonella
MeSH headings : Animals; Bartonella / isolation & purification; Bartonella Infections / microbiology; Bartonella Infections / veterinary; DNA, Bacterial; Dog Diseases / microbiology; Dogs; Female; Male; Serologic Tests; Seroma / microbiology; Synovial Fluid / microbiology
TL;DR: Dogs can be co-infected with two Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Comparative Activity of Pradofloxacin, Enrofloxacin, and Azithromycin against Bartonella henselae Isolates Collected from Cats and a Human

Journal of Clinical Microbiology, 48(2), 617–618.

By: S. Biswas n, R. Maggi n, M. Papich n, D. Keil* & E. Breitschwerdt n

MeSH headings : Angiomatosis, Bacillary / microbiology; Angiomatosis, Bacillary / veterinary; Animals; Anti-Bacterial Agents / pharmacology; Azithromycin / pharmacology; Bartonella henselae / drug effects; Bartonella henselae / isolation & purification; Cat Diseases / microbiology; Cat-Scratch Disease / microbiology; Cats; Enrofloxacin; Fluoroquinolones / pharmacology; Humans; Microbial Sensitivity Tests
TL;DR: It is concluded that pradofloxacin may prove useful for the treatment of B. henselae infections and showed greater antimicrobial activity than did other antibiotics. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Comparative medical features of canine and human bartonellosis

Clinical Microbiology and Infection, 15, 106–107.

By: E. Breitschwerdt n & R. Maggi n

MeSH headings : Animals; Antibodies, Bacterial / blood; Bacteriological Techniques / methods; Bartonella / genetics; Bartonella / growth & development; Bartonella / immunology; Bartonella / isolation & purification; Bartonella Infections / pathology; Bartonella Infections / veterinary; DNA, Bacterial / blood; DNA, Bacterial / genetics; Dog Diseases / pathology; Dogs; Female; Fluorescent Antibody Technique, Indirect; Humans; Male; Polymerase Chain Reaction
TL;DR: Current evi-dence indicates that canids, including coyotes, dogs and grey foxes, potentially serve as reservoirhosts for Bartonella species, and it is unclear how dogs become infected and whether dogsserve as accidental hosts or as chronically bacte-raemic reservoirs for B. henselae. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Cross-contamination in the Molecular Detection of Bartonella from Paraffin-embedded Tissues

Veterinary Pathology, 46(5), 940–944.

By: M. Varanat n, R. Maggi n, K. Linder n, S. Horton n & E. Breitschwerdt n

author keywords: Bartonellosis; cross-contamination; necropsy; paraffin-embedded tissue; PCR contamination
MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Equipment Contamination; Polymerase Chain Reaction / methods
TL;DR: Unless stringent procedures are established and followed to avoid cross-contamination, the molecular detection of Bartonella spp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Ecological fitness and strategies of adaptation of Bartonella species to their hosts and vectors

Veterinary Research, 40(2), 29.

By: B. Chomel*, H. Boulouis*, E. Breitschwerdt n, R. Kasten*, M. Vayssier-Taussat*, R. Birtles*, J. Koehler*, C. Dehio*

author keywords: Bartonella; vectors; ecological fitness; host adaptation; pathogenesis
MeSH headings : Adaptation, Physiological; Animals; Bartonella / classification; Bartonella / physiology; Disease Reservoirs; Ecosystem; Humans; Insect Vectors / microbiology; Insecta / microbiology
TL;DR: Bacterial type IV secretion systems, which are supra-molecular transporters ancestrally related to bacterial conjugation systems, represent crucial pathogenicity factors that have contributed to a radial expansion of the Bartonella lineage in nature by facilitating adaptation to unique mammalian hosts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

High Prevalence of Tick-Borne Pathogens in Dogs from an Indian Reservation in Northeastern Arizona

Vector-Borne and Zoonotic Diseases, 10(2), 117–123.

By: P. Diniz n, M. Beall*, K. Omark, R. Chandrashekar*, D. Daniluk*, K. Cyr*, J. Koterski*, R. Robbins ...

author keywords: Anaplasma; Babesia; Bartonella; Ehrlichia; Rickettsia; Sentinel
MeSH headings : Anaplasma / isolation & purification; Anaplasmosis / epidemiology; Animals; Arizona / epidemiology; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Ehrlichia / isolation & purification; Ehrlichiosis / epidemiology; Ehrlichiosis / veterinary; Female; Host-Pathogen Interactions; Male; Prevalence; Tick Infestations / epidemiology; Tick Infestations / veterinary
TL;DR: Dogs on this Hopi Indian reservation were most frequently infected with E. canis or A. platys; however, more than half of the dogs were exposed to a SFG-Rickettsia species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Infection and replication of Bartonella species within a tick cell line

Experimental and Applied Acarology, 49(3), 193–208.

By: S. Billeter n, P. Diniz n, J. Battisti*, U. Munderloh*, E. Breitschwerdt n & M. Levy n

author keywords: Bartonella species; Tick cell lines; Bacteria; Replication; Cell culture
MeSH headings : Animals; Bacteriological Techniques; Bartonella / cytology; Bartonella / isolation & purification; Bartonella / physiology; Cell Culture Techniques; Cells, Cultured; Culture Media, Conditioned; DNA, Bacterial; Ticks / microbiology
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Isolation of Bartonella vinsonii subsp. berkhoffii Genotype II from a Boy with Epithelioid Hemangioendothelioma and a Dog with Hemangiopericytoma

Journal of Clinical Microbiology, 47(6), 1957–1960.

By: E. Breitschwerdt n, R. Maggi n, M. Varanat n, K. Linder n & G. Weinberg n

MeSH headings : Adolescent; Animals; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Dog Diseases / microbiology; Dogs; Female; Genotype; Hemangioendothelioma, Epithelioid / complications; Hemangiopericytoma / complications; Hemangiopericytoma / veterinary; Humans; Male
TL;DR: Results suggest that B. vinsonii subsp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Isolation or Molecular Detection of Bartonella henselae and Bartonella vinsonii subsp. berkhoffii from Dogs with Idiopathic Cavitary Effusions

Journal of Veterinary Internal Medicine, 23(1), 186–189.

By: N. Cherry n, P. Diniz n, R. Maggi n, J. Hummel n, E. Hardie n, E. Behrend*, E. Rozanski*, T. DeFrancesco n ...

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bartonella / classification; Bartonella / isolation & purification; Bartonella Infections / drug therapy; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Female; Male; Pericardial Effusion / drug therapy; Pericardial Effusion / microbiology; Pericardial Effusion / veterinary; Pleural Effusion / drug therapy; Pleural Effusion / microbiology; Pleural Effusion / veterinary
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Lack of Evidence for Perinatal Transmission of Canine Granulocytic Anaplasmosis From a Bitch to Her Offspring

Journal of the American Animal Hospital Association, 45(5), 232–238.

By: M. Plier*, E. Breitschwerdt*, B. Hegarty* & L. Kidd*

MeSH headings : Anaplasma phagocytophilum; Animals; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Doxycycline / adverse effects; Doxycycline / therapeutic use; Ehrlichiosis / drug therapy; Ehrlichiosis / transmission; Ehrlichiosis / veterinary; Female; Infectious Disease Transmission, Vertical / veterinary; Pregnancy; Pregnancy Complications, Infectious / drug therapy; Pregnancy Complications, Infectious / microbiology; Pregnancy Complications, Infectious / veterinary; Teratogens
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 2, 2020

2009 journal article

Managing canine vector-borne diseases of zoonotic concern: part one

Trends in Parasitology, 25(4), 157–163.

By: D. Otranto*, F. Dantas-Torres* & E. Breitschwerdt n

MeSH headings : Animals; Disease Reservoirs / microbiology; Disease Reservoirs / parasitology; Disease Reservoirs / veterinary; Disease Vectors; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Humans; Zoonoses / epidemiology; Zoonoses / microbiology; Zoonoses / parasitology
TL;DR: This review focuses on the zoonotic relevance of CVBDs, the significance of co-infection and the role of infected but clinically healthy dogs in spreading different pathogens among human and canine populations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Managing canine vector-borne diseases of zoonotic concern: part two

Trends in Parasitology, 25(5), 228–235.

By: D. Otranto*, F. Dantas-Torres* & E. Breitschwerdt n

MeSH headings : Animals; Disease Vectors; Dog Diseases / microbiology; Dog Diseases / parasitology; Dog Diseases / prevention & control; Dog Diseases / transmission; Dogs; Humans; Zoonoses / epidemiology; Zoonoses / microbiology; Zoonoses / parasitology; Zoonoses / transmission
TL;DR: A better understanding of the pathogenesis and the progression of clinical, hematological and biochemical abnormalities of CVBDs will be important in choosing appropriate diagnostic tests and in establishing the best strategies for treatment and control. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Molecular Documentation of Bartonella Infection in Dogs in Greece and Italy

Journal of Clinical Microbiology, 47(5), 1565–1567.

By: P. Diniz n, S. Billeter n, D. Otranto*, D. De Caprariis*, T. Petanides, M. Mylonakis*, A. Koutinas*, E. Breitschwerdt n

MeSH headings : Animals; Bacterial Proteins / genetics; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / veterinary; Cluster Analysis; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Ribosomal / chemistry; DNA, Ribosomal / genetics; DNA, Ribosomal Spacer / chemistry; DNA, Ribosomal Spacer / genetics; DNA-Directed RNA Polymerases / genetics; Dog Diseases / microbiology; Dogs; Europe; Genes, rRNA; Molecular Sequence Data; Phylogeny; RNA, Bacterial / genetics; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid
TL;DR: DNA sequencing evidence of a potentially new Bartonella sp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Molecular Epidemiology of Feline and Human Bartonella henselae Isolates

Emerging Infectious Diseases, 15(5), 813–816.

By: R. Bouchouicha*, B. Durand*, M. Monteil*, B. Chomel, M. Berrich*, M. Arvand, R. Birtles*, E. Breitschwerdt n ...

MeSH headings : Animals; Bacterial Typing Techniques; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella henselae / classification; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Cat Diseases / epidemiology; Cat Diseases / microbiology; Cats; DNA, Bacterial / analysis; DNA, Bacterial / isolation & purification; Evolution, Molecular; Genotype; Humans; Minisatellite Repeats / genetics; Molecular Epidemiology; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA
TL;DR: Multiple locus variable number tandem repeat analysis was performed on 178 Bartonella henselae isolates from 9 countries; 99 profiles were distributed into 2 groups and the evolutive implications are discussed. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Molecular mechanisms of Bartonella henselae resistance to azithromycin, pradofloxacin and enrofloxacin

Journal of Antimicrobial Chemotherapy, 65(3), 581–582.

By: S. Biswas n, R. Maggi n, M. Papich n & E. Breitschwerdt n

author keywords: in vitro resistant mutants; disc diffusion assay; bartonellosis; DNA gyrase A; 23S rRNA
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Azithromycin / pharmacology; Bacteremia / microbiology; Bacterial Proteins / genetics; Bartonella henselae / drug effects; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Cat Diseases / microbiology; Cats; DNA Gyrase / genetics; DNA Mutational Analysis; DNA, Bacterial / genetics; Drug Resistance, Bacterial; Enrofloxacin; Fluoroquinolones / pharmacology; Mutation; Polymerase Chain Reaction; RNA, Ribosomal, 23S / genetics; Sequence Analysis, DNA
TL;DR: In vitro results might explain relapses or treatment failures in vivo when using azithromycin as the sole antibiotic for treatment of cats infected with B. henselae, and many independent lines of evidence indicate that adenosine 2058 is the key nucleotide involved in macrolide interaction with the bacterial ribosome. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2009 journal article

Prevention of transmission of ehrlichia SPP

Compendium-Continuing Education for Veterinarians, 31(8A), 8–9.

By: E. Britschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2009 journal article

Recurrent Osteomyelitis in a Cat due to Infection with Bartonella vinsonii subsp. berkhoffii Genotype II

Journal of Veterinary Internal Medicine, 23(6), 1273–1277.

By: M. Varanat n, A. Travis*, W. Lee n, R. Maggi n, S. Bissett n, K. Linder n, E. Breitschwerdt n

MeSH headings : Amoxicillin-Potassium Clavulanate Combination / therapeutic use; Animals; Anti-Bacterial Agents / therapeutic use; Azithromycin / therapeutic use; Bartonella / classification; Bartonella / genetics; Bartonella Infections / drug therapy; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Cat Diseases / drug therapy; Cat Diseases / microbiology; Cats; Female; Osteomyelitis / drug therapy; Osteomyelitis / microbiology; Osteomyelitis / veterinary
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 conference paper

Atovaquone and azithromycin for the treatment of cytauxzoon felis

Journal of Veterinary Internal Medicine, 22(3), 703–704.

By: A. Birkenheuer, L. Cohn, M. Levy, E. Breitschwerdt & H. Marr

Event: 26th Annual American College of Veterinary Internal Medicine Forum at San Antonio, TX on June 4-7, 2008

Source: NC State University Libraries
Added: March 16, 2021

2008 journal article

Bartonella DNA in the Blood and Lymph Nodes of Golden Retrievers with Lymphoma and in Healthy Controls

Journal of Veterinary Internal Medicine, 22(1), 89–95.

By: A. Duncan n, H. Marr n, A. Birkenheuer n, R. Maggi n, L. Williams n, M. Correa n, E. Breitschwerdt n

author keywords: bacteria; cancer; dog; tick; vector-borne
MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / complications; Bartonella Infections / veterinary; Case-Control Studies; DNA, Bacterial / analysis; DNA, Bacterial / blood; Disease Vectors; Dog Diseases / blood; Dog Diseases / microbiology; Dogs; Female; Lymph Nodes / microbiology; Lymphoma / microbiology; Lymphoma / veterinary; Male; Models, Statistical; Polymerase Chain Reaction / veterinary; Risk Factors; Surveys and Questionnaires
TL;DR: Bartonella DNA can be detected in blood and lymph nodes; importantly, in this report, Bartonella was detected in the same proportion of clinically healthy dogs and dogs with lymphoma. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2008 journal article

Bartonella Henselae in Captive and Hunter-Harvested Beluga (Delphinapterus Leucas)

Journal of Wildlife Diseases, 44(4), 871–877.

By: R. Maggi n, S. Raverty*, S. Lester*, D. Huff*, M. Haulena*, S. Ford, O. Nielsen*, J. Robinson*, E. Breitschwerdt n

author keywords: Bartonella; beluga; captive; Delphinapterus leucas; free-ranging
MeSH headings : Angiomatosis, Bacillary / epidemiology; Angiomatosis, Bacillary / microbiology; Angiomatosis, Bacillary / transmission; Angiomatosis, Bacillary / veterinary; Animals; Animals, Wild / virology; Animals, Zoo / virology; Bartonella henselae / classification; Bartonella henselae / isolation & purification; Beluga Whale / microbiology; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Intergenic / chemistry; DNA, Intergenic / genetics; Male; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Spleen / virology
TL;DR: Using polymerase chain reaction analyses targeting the intergenic spacer region (ITS), two B. henselae ITS strains were identified in 78% of captive and free-ranging hunter-harvested belugas and may influence aquarium management procedures for captive marine mammals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Bartonella sp. Bacteremia in Patients with Neurological and Neurocognitive Dysfunction

Journal of Clinical Microbiology, 46(9), 2856–2861.

By: E. Breitschwerdt n, R. Maggi n, W. Nicholson*, N. Cherry n & C. Woods*

MeSH headings : Adolescent; Adult; Bartonella; Bartonella Infections / microbiology; Bartonella henselae; Cognition Disorders / microbiology; Female; Humans; Male; Middle Aged; Nervous System Diseases / microbiology; Young Adult
TL;DR: infection with a Bartonella species (B. henselae or B. vinsonii subsp. berkhoffii) in blood samples from six immunocompetent patients who presented with a chronic neurological or neurocognitive syndrome including seizures, ataxia, memory loss, and/or tremors. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Bartonella species detection in captive, stranded and free-ranging cetaceans

Veterinary Research, 39(6), 59.

By: C. Harms n, R. Maggi n, E. Breitschwerdt n, C. Clemons-Chevis*, M. Solangi*, D. Rotstein*, P. Fair*, L. Hansen* ...

MeSH headings : Animals; Bartonella / classification; Bartonella / isolation & purification; Bartonella Infections / microbiology; Dolphins; Female; Male; Porpoises
TL;DR: Although disease causation has not been established, Bartonella species were detected more commonly from cetaceans that were overtly debilitated or were cohabiting in captivity with a debiltated animal than from free-ranging animals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Bartonella-Associated Meningoradiculoneuritis and Dermatitis or Panniculitis in 3 Dogs

Journal of Veterinary Internal Medicine, 22(3), 674–678.

By: J. Cross*, J. Rossmeisl*, R. Maggi n, E. Breitschwerdt n & R. Duncan*

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bartonella / isolation & purification; Bartonella Infections / drug therapy; Bartonella Infections / veterinary; Central Nervous System Bacterial Infections / diagnosis; Central Nervous System Bacterial Infections / drug therapy; Central Nervous System Bacterial Infections / microbiology; Central Nervous System Bacterial Infections / veterinary; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Female; Male; Panniculitis / drug therapy; Panniculitis / microbiology; Panniculitis / veterinary; Radiculopathy / diagnosis; Radiculopathy / drug therapy; Radiculopathy / microbiology; Radiculopathy / veterinary; Skin Diseases, Bacterial / drug therapy; Skin Diseases, Bacterial / microbiology; Skin Diseases, Bacterial / veterinary
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Concurrent Hepatic Copper Toxicosis and Fanconi's Syndrome in a Dog

Journal of Veterinary Internal Medicine, 22(1), 219–222.

By: T. Hill n, E. Breitschwerdt n, T. Cecere n & S. Vaden n

MeSH headings : Animals; Chelation Therapy / veterinary; Chemical and Drug Induced Liver Injury; Copper / metabolism; Dog Diseases / chemically induced; Dog Diseases / diagnosis; Dog Diseases / therapy; Dogs; Fanconi Syndrome / diagnosis; Fanconi Syndrome / therapy; Fanconi Syndrome / veterinary; Kidney / pathology; Liver / pathology; Liver Diseases / diagnosis; Liver Diseases / veterinary; Male; Metal Metabolism, Inborn Errors / diagnosis; Metal Metabolism, Inborn Errors / therapy; Metal Metabolism, Inborn Errors / veterinary
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2008 journal article

Coxiella-Like Infection in Psittacines and a Toucan

Avian Diseases, 52(3), 426–432.

By: H. Shivaprasad*, M. Cadenas*, S. Diab, R. Nordhausen, D. Bradway*, R. Crespo*, E. Breitschwerdt*

Contributors: H. Shivaprasad*, M. Cadenas*, S. Diab, R. Nordhausen, D. Bradway*, R. Crespo*, E. Breitschwerdt*

author keywords: avian; psittacines; toucan; hepatitis; splenitis; Coxiella
MeSH headings : Animals; Base Sequence; Bird Diseases / microbiology; Bird Diseases / pathology; Coxiella / genetics; DNA Primers / genetics; Fatal Outcome; Gram-Negative Bacterial Infections / pathology; Gram-Negative Bacterial Infections / veterinary; Immunohistochemistry; Liver / ultrastructure; Microscopy, Electron; Molecular Sequence Data; Psittaciformes; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA
TL;DR: This is the first documentation of disease presumptively associated with Coxiella-like bacteria in birds, based on polymerase chain reaction and bacterial 16S rRNA gene sequence obtained from each bird's liver tissue. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2008 journal article

Detection of two Bartonella tamiae-like sequences in Amblyomma americanum (Acari : Ixodidae) using 16S-23S intergenic spacer region-specific primers

JOURNAL OF MEDICAL ENTOMOLOGY, 45(1), 176–179.

By: S. Billeter n, M. Miller, E. Breitschwerdt* & M. Levy*

author keywords: Bartonella; Amblyomma americanum; PCR
TL;DR: Based upon PCR and sequencing, an adult male and adult female tick harbored DNA sequences closely related to Bartonella tamiae (DQ395180) and potential transmission of Bart onella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2008 journal article

Detection ofBartonella henselaein the Blood of 2 Adult Horses

Journal of Veterinary Internal Medicine, 22(2), 495–498.

By: S. Jones n, R. Maggi n, J. Shuler n, A. Alward n & E. Breitschwerdt n

author keywords: arthropathy; bartonellosis; purpura hemorrhagica; vasculitis
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacteremia / drug therapy; Bacteremia / microbiology; Bacteremia / veterinary; Bartonella Infections / blood; Bartonella Infections / drug therapy; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Culture Media; DNA, Bacterial / blood; Female; Horse Diseases / blood; Horse Diseases / drug therapy; Horse Diseases / microbiology; Horses; Joint Diseases / drug therapy; Joint Diseases / microbiology; Joint Diseases / veterinary; Male; Polymerase Chain Reaction / veterinary; Vasculitis / drug therapy; Vasculitis / microbiology; Vasculitis / veterinary
TL;DR: The presence of Bartonella sp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2008 conference paper

Duration of infection and efficacy of doxycycline treatment in dogs experimentally co-infected with anaplasma platys and ehrlichia canis

Journal of Veterinary Internal Medicine, 22(3), 703.

By: M. Beall, S. Gaunt, R. Chandrashekar, K. DeBisceglie, B. Thatcher, P. Diniz, E. Breitschwerdt

Event: 26th Annual American College of Veterinary Internal Medicine Forum at San Antonio, TX on June 4-7, 2008

Source: NC State University Libraries
Added: March 16, 2021

2008 conference paper

Dynamics of exposure to vector-borne organisms in dogs in North America: 2004-2006

Journal of Veterinary Internal Medicine, 22(3), 784.

By: P. Diniz, M. Morgado, B. Hegarty, N. Cherry, M. Sullivan & E. Breitschwerdt

Event: 26th Annual American College of Veterinary Internal Medicine Forum at San Antonio, TX on June 4-7, 2008

Source: NC State University Libraries
Added: March 16, 2021

2008 conference paper

Experimental E-canis infection in dogs: Antibody responses pre- and post-treatment

Journal of Veterinary Internal Medicine, 22(3), 781–782.

By: B. Stillman, K. Caterina-DeBisceglie, J. Bradley, J. Saucier, E. Breitschwerdt, S. Gaunt, T. O'Connor, R. Chandrashekar

Event: 26th Annual American College of Veterinary Internal Medicine Forum at San Antonio, TX on June 4-7, 2008

Source: NC State University Libraries
Added: March 16, 2021

2008 journal article

Factors Associated with the Occurrence of Epistaxis in Natural Canine Leishmaniasis (Leishmania infantum)

Journal of Veterinary Internal Medicine, 22(4), 866–872.

By: T. Petanides, A. Koutinas*, M. Mylonakis*, M. Day*, M. Saridomichelakis*, L. Leontides*, R. Mischke*, P. Diniz n ...

author keywords: dysproteinemia; rhinitis; thrombocytopathy
MeSH headings : Animals; Dog Diseases / parasitology; Dogs; Epistaxis / etiology; Epistaxis / veterinary; Female; Leishmania infantum; Leishmaniasis, Visceral / complications; Leishmaniasis, Visceral / veterinary; Male
TL;DR: CanL-associated epistaxis appears to be the result of multiple and variable pathogenetic factors such as thrombocytopathy, hyperglobulinemia-induced serum hyperviscosity, and nasal mucosa ulceration. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Failure to identify an association between serologic or molecular evidence ofBartonellainfection and idiopathic rhinitis in dogs

Journal of the American Veterinary Medical Association, 233(4), 597–599.

By: E. Hawkins n, L. Johnson, L. Guptill*, H. Marr n, E. Breitschwerdt n & A. Birkenheuer n

MeSH headings : Animals; Antibodies, Bacterial / blood; Bartonella / immunology; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella henselae / immunology; Bartonella henselae / isolation & purification; Case-Control Studies; DNA, Bacterial / analysis; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Female; Fluorescent Antibody Technique, Indirect / methods; Fluorescent Antibody Technique, Indirect / veterinary; Male; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Rhinitis / diagnosis; Rhinitis / microbiology; Rhinitis / veterinary
TL;DR: The failure to find any evidence of exposure to or infection with Bartonella spp in dogs with idiopathic nasal discharge suggested that Bart onella infection was not a common cause of the disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2008 journal article

Feline bartonellosis and cat scratch disease

Veterinary Immunology and Immunopathology, 123(1-2), 167–171.

By: E. Breitschwerdt n

author keywords: cat; bartonella; cat scratch disease; epidemiology
MeSH headings : Animals; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / transmission; Cat Diseases / epidemiology; Cat Diseases / microbiology; Cat Diseases / transmission; Cat-Scratch Disease / epidemiology; Cat-Scratch Disease / microbiology; Cat-Scratch Disease / transmission; Cats; Disease Reservoirs / microbiology; Disease Reservoirs / veterinary; Humans; Siphonaptera / microbiology; Zoonoses / microbiology
TL;DR: As fleas are involved in the transmission among cats, the use of acaracide products to eliminate fleas from the environment is of critical importance to decrease the risk of B. henselae Transmission among cats and to humans. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Isolation of Candidatus Bartonella melophagi from Human Blood

Emerging Infectious Diseases, 15(1), 66–68.

By: R. Maggi n, M. Kosoy n, M. Mintzer n & E. Breitschwerdt n

MeSH headings : Aged; Animals; Bacteremia / microbiology; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / complications; Bartonella Infections / microbiology; Bartonella henselae / classification; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Blood / microbiology; Citrate (si)-Synthase / genetics; Culture Media; DNA, Ribosomal Spacer / analysis; Female; Humans; Middle Aged; RNA Polymerase II / genetics; RNA, Ribosomal, 16S / genetics; RNA, Ribosomal, 23S / genetics; Sheep / microbiology
TL;DR: Candidatus Bartonella melophagi was isolated by blood culture from 2 women, 1 of whom was co-infected with B. henselae, and partial 16S rRNA, RNA polymerase B, and citrate synthase genes and 16S–23S internal transcribed spacer sequences indicated that human isolates were similar to Candidatus B.melophagi. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Molecular Characterization of Bartonella vinsonii subsp. berkhoffii Genotype III

Journal of Clinical Microbiology, 46(5), 1858–1860.

By: M. Cadenas n, J. Bradley n, R. Maggi n, M. Takara n, B. Hegarty n & E. Breitschwerdt n

MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Blood / microbiology; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Dog Diseases / microbiology; Dogs; Endocarditis, Bacterial / microbiology; Female; Genes, Bacterial; Genotype; Molecular Sequence Data
TL;DR: The molecular characterization of a Bartonella vinsonii subsp. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 1, 2020

2008 journal article

Molecular characterization of Bartonella vinsonii subsp berkhoffii genotype III

Journal of Clinical Microbiology, 46(5), 1858–1860.

By: M. Cadenas, J. Bradley, R. Maggi, M. Takara, B. Hegarty & E. Breitschwerdt

Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2008 journal article

PCR detection of Bartonella bovis and Bartonella henselae in the blood of beef cattle

Veterinary Microbiology, 135(3-4), 308–312.

By: N. Cherry n, R. Maggi n, A. Cannedy n & E. Breitschwerdt n

author keywords: Cattle; Bartonella bovis; Bartonella henselae; Co-infection; Bacteremia
MeSH headings : Angiomatosis, Bacillary / diagnosis; Angiomatosis, Bacillary / veterinary; Animals; Bacteremia / diagnosis; Bacteremia / veterinary; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Cattle; Cattle Diseases / diagnosis; Cattle Diseases / microbiology; DNA Primers; DNA, Bacterial / genetics; DNA, Bacterial / isolation & purification; Introns; Meat / microbiology; North Carolina; Polymerase Chain Reaction / methods; RNA, Bacterial / genetics; RNA, Bacterial / isolation & purification; RNA, Ribosomal / genetics; RNA, Ribosomal / isolation & purification
TL;DR: This study describes the first detection of B. henselae in any large ruminant species in the world and supports the need for further investigation of prevalence and pathogenic potential of b. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Prevalence of Bartonella species antibodies and Bartonella species DNA in the blood of cats with and without fever

Journal of Feline Medicine and Surgery, 11(2), 141–148.

By: M. Lappin*, E. Breitschwerdt n, M. Brewer*, J. Hawley*, B. Hegarty n & S. Radecki*

MeSH headings : Animals; Antibodies, Bacterial / blood; Bartonella / genetics; Bartonella / immunology; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella henselae / genetics; Bartonella henselae / immunology; Bartonella henselae / isolation & purification; Blotting, Western / standards; Blotting, Western / veterinary; Cat Diseases / blood; Cat Diseases / epidemiology; Cat Diseases / microbiology; Cats; DNA, Bacterial / blood; Enzyme-Linked Immunosorbent Assay / standards; Enzyme-Linked Immunosorbent Assay / veterinary; Fever / blood; Fever / microbiology; Fever / veterinary; Immunodominant Epitopes / immunology; Immunoglobulin G / blood; Polymerase Chain Reaction / standards; Polymerase Chain Reaction / veterinary; Predictive Value of Tests; Prevalence
TL;DR: The results of this study indicate that in cats, Bartonella species antibody tests cannot predict whether fever is due to Bart onella species infection and should not be used to determine the Bartoneella species infection status. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Serological and Molecular Prevalence of Borrelia burgdorferi, Anaplasma phagocytophilum, and Ehrlichia Species in Dogs from Minnesota

Vector-Borne and Zoonotic Diseases, 8(4), 455–464.

By: M. Beall*, R. Chandrashekar*, M. Eberts*, K. Cyr*, P. Diniz n, C. Mainville*, B. Hegarty n, J. Crawford n, E. Breitschwerdt n

author keywords: tick(s)
MeSH headings : Anaplasma phagocytophilum / isolation & purification; Animals; Antibodies, Bacterial / blood; Borrelia burgdorferi / isolation & purification; Dog Diseases / blood; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Ehrlichia / isolation & purification; Ehrlichiosis / epidemiology; Ehrlichiosis / veterinary; Female; Lyme Disease / epidemiology; Lyme Disease / veterinary; Male; Minnesota / epidemiology; Prevalence; Time Factors
TL;DR: A population of 731 naturally exposed pet dogs examined at a private practice in Baxter, Minnesota, an area endemic for Lyme disease and anaplasmosis, was tested by serological and molecular methods for evidence of exposure to or infection with selected vector-borne pathogens, finding A. phagocytophilum DNA was more prevalent in suspected cases of anaplasmsosis or borreliosis than in healthy dogs from the same region. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Serum Cardiac Troponin I Concentration in Dogs with Ehrlichiosis

Journal of Veterinary Internal Medicine, 22(5), 1136–1143.

By: P. Diniz n, H. de Morais*, E. Breitschwerdt n & D. Schwartz*

author keywords: canine monocytic ehrlichiosis; myocarditis; risk factor; SIRS; troponin
MeSH headings : Animals; Biomarkers / blood; Dog Diseases / blood; Dogs; Ehrlichiosis / blood; Ehrlichiosis / veterinary; Female; Heart Diseases / blood; Heart Diseases / complications; Heart Diseases / veterinary; Male; Odds Ratio; Risk Factors; Troponin I / blood
TL;DR: Severity of anemia and SIRS might contribute to the pathophysiology of myocardial damage in naturally infected Brazilian dogs. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2008 journal article

Use of broad range16S rDNA PCR in clinical microbiology

Journal of Microbiological Methods, 76(3), 217–225.

By: S. Sontakke*, M. Cadenas n, R. Maggi n, P. Diniz n & E. Breitschwerdt n

author keywords: Bacterial genes; Broad range PCR; DNA sequencing; Diagnostics
MeSH headings : Bacteria / classification; Bacteria / genetics; Bacterial Infections / diagnosis; Bacterial Infections / veterinary; Bacteriological Techniques; DNA, Ribosomal / genetics; Humans; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / standards; Polymerase Chain Reaction / veterinary; Predictive Value of Tests; RNA, Bacterial / genetics; RNA, Ribosomal, 16S / genetics; Sensitivity and Specificity
TL;DR: A more uniform consensus on the accurate interpretation of broad range 16S rDNA PCR results are needed to improve the microbiological utility of this modality for the diagnosis of bacterial infections in animals and in human patients. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2008 journal article

Vector transmission of Bartonella species with emphasis on the potential for tick transmission

Medical and Veterinary Entomology, 22(1), 1–15.

By: S. Billeter n, M. Levy n, B. Chomel n & E. Breitschwerdt n

author keywords: Bartonella species; arthropods; DNA; PCR; ticks; vector competence; vector potential
MeSH headings : Animals; Arachnid Vectors / microbiology; Bartonella / isolation & purification; Bartonella Infections / transmission; Bartonella Infections / veterinary; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Disease Reservoirs; Humans; Insect Vectors / microbiology; Phthiraptera / microbiology; Siphonaptera / microbiology; Ticks / microbiology; Zoonoses
TL;DR: A review of Bartonella transmission by sandflies, lice and fleas, the potential for transmission by other vectors, and data supporting transmission by ticks suggests there is substantial opportunity for the potential uptake of these blood‐borne bacteria by a variety of arthropod vectors that feed on animals and people. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2007 journal article

A combined approach for the enhanced detection and isolation of Bartonella species in dog blood samples: Pre-enrichment liquid culture followed by PCR and subculture onto agar plates

Journal of Microbiological Methods, 69(2), 273–281.

By: A. Duncan n, R. Maggi n & E. Breitschwerdt n

author keywords: Bartonella; culture; detection; dog; isolation
MeSH headings : Agar; Animals; Antibodies, Bacterial / blood; Bartonella Infections / blood; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella henselae / genetics; Bartonella henselae / immunology; Bartonella henselae / isolation & purification; Cell Culture Techniques / methods; Cell Culture Techniques / veterinary; Culture Media; DNA, Bacterial / blood; DNA, Bacterial / genetics; DNA, Ribosomal Spacer / chemistry; DNA, Ribosomal Spacer / genetics; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Female; Fluorescent Antibody Technique, Indirect / veterinary; Immunoglobulin G / blood; Male; Polymerase Chain Reaction / veterinary; Prospective Studies; Sequence Analysis, DNA
TL;DR: A multi-faceted approach resulted in substantial improvement in the microbiological detection and isolation of Bartonella when compared to direct inoculation of a blood agar plate, and may assist in the diagnostic confirmation of bartonellosis in dogs and other animals. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2007 journal article

Bartonella DNA in Loggerhead Sea Turtles

Emerging Infectious Diseases, 13(6), 949–950.

By: K. Valentine n, C. Harms n, M. Cadenas n, A. Birkenheuer n, H. Marr n, J. Braun-McNeill*, R. Maggi n, E. Breitschwerdt n

MeSH headings : Animals; Atlantic Ocean; Bartonella / genetics; Bartonella / isolation & purification; Bartonella / pathogenicity; Bartonella Infections / blood; Bartonella Infections / genetics; Bartonella Infections / veterinary; DNA, Bacterial / classification; North Carolina; Polymerase Chain Reaction; Turtles / blood; Turtles / microbiology
TL;DR: Pathogenic bacteria are an important threat in terrestrial and marine environments, and in the case of B. henselae, reservoir hosts may be more diverse than currently recognized. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2007 journal article

Bartonella vinsonii subsp berkhoffii endocarditis in a dog from Saskatchewan

Canadian Veterinary Journal, 48(8), 839–844.

By: K. Cockwill, S. Taylor, H. Phillbert, E. Breitschwerdt & R. Maggi

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

BartonellaDNA in Dog Saliva

Emerging Infectious Diseases, 13(12), 1948–1950.

By: A. Duncan n, R. Maggi n & E. Breitschwerdt n

MeSH headings : Animals; Bartonella; DNA, Bacterial / isolation & purification; Dogs; Saliva / microbiology
TL;DR: Oral swabs collected from dogs indicated the presence of 4 Bartonella species, transmitted by arthropods or animal bites and scratches, which are emerging pathogens in human and veterinary medicine. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2007 journal article

BartonellaSpecies in Blood of Immunocompetent Persons with Animal and Arthropod Contact

Emerging Infectious Diseases, 13(6), 938–941.

By: E. Breitschwerdt n, R. Maggi n, A. Duncan n, W. Nicholson*, B. Hegarty n & C. Woods*

MeSH headings : Adult; Animals; Arthropod Vectors; Bacteremia / blood; Bacteremia / microbiology; Bacteriological Techniques; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / genetics; Bartonella Infections / transmission; Bites and Stings; Cats; Dogs; Female; Humans; Immunocompetence; Male; Middle Aged; Molecular Sequence Data; North Carolina / epidemiology; Polymerase Chain Reaction; Seroepidemiologic Studies; Serologic Tests; Zoonoses
TL;DR: Using PCR in conjunction with pre-enrichment culture, it is detected Bartonella henselae and B. vinsonii subspecies berkhoffii in the blood of 14 immunocompetent persons who had frequent animal contact and arthropod exposure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2007 journal article

Canine bartonellosis: serological and molecular prevalence in Brazil and evidence of co-infection with Bartonella henselae and Bartonella vinsonii subsp berkhoffii

VETERINARY RESEARCH, 38(5), 697–710.

By: P. Vissotto De Paiva Diniz n, R. Maggi n, D. Schwartz*, M. Cadenas n, J. Bradley n, B. Hegarty n, E. Breitschwerdt n

author keywords: dogs; Bartonella infections; heart disease; culture; Brazil
MeSH headings : Angiomatosis, Bacillary / epidemiology; Angiomatosis, Bacillary / veterinary; Animals; Antibodies, Bacterial / blood; Bartonella / immunology; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Bartonella henselae / immunology; Brazil / epidemiology; DNA, Bacterial / analysis; Dog Diseases / epidemiology; Dogs; Female; Gene Amplification; Male; Prospective Studies; Seroepidemiologic Studies
TL;DR: It is concluded that dogs in this study population were infrequently exposed to or infected with a Bartonella species, genetically similar to strains isolated from septicemic cats, dogs, coyotes and human beings from other parts of the world. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 journal article

Detection of “Rickettsia amblyommii” in Association with a Tick Bite Rash

Vector-Borne and Zoonotic Diseases, 7(4), 607–610.

By: S. Billeter n, H. Blanton n, S. Little*, M. Levy n & E. Breitschwerdt n

author keywords: "Rickettsia amblyommii"; tick bite rash; Amblyomma americanum; STARI
MeSH headings : Animals; Bacterial Outer Membrane Proteins / genetics; Base Sequence; Bites and Stings / complications; Bites and Stings / microbiology; Exanthema / etiology; Exanthema / microbiology; Female; Humans; Rickettsia / genetics; Rickettsia / isolation & purification; Rickettsia Infections / complications; Rickettsia Infections / microbiology; Sequence Alignment; Sequence Homology, Nucleic Acid; South Carolina; Tick-Borne Diseases / complications; Tick-Borne Diseases / microbiology; Ticks / microbiology
TL;DR: This is the first case in which R. amblyommii was temporally associated with a rash and when examined by polymerase chain reaction for Borrelia, Anaplasma, Ehrlichia, Babesia,Rickettsia, and Bartonella DNA, only the Rickettsia primers generated an amplicon. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2007 journal article

Detection ofBartonella henselaeDNA in two dogs with pyogranulomatous lymphadenitis

Journal of the American Veterinary Medical Association, 230(5), 681–685.

By: S. Morales*, E. Breitschwerdt n, R. Washabau*, I. Matise*, R. Maggi n & A. Duncan n

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bartonella henselae / isolation & purification; Cat-Scratch Disease / diagnosis; Cat-Scratch Disease / drug therapy; Cat-Scratch Disease / microbiology; DNA, Bacterial / analysis; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Drug Therapy, Combination; Lymphadenitis / diagnosis; Lymphadenitis / drug therapy; Lymphadenitis / microbiology; Lymphadenitis / veterinary; Male; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Treatment Outcome
TL;DR: Quantitative real-time PCR assays detected Bartonella henselae DNA in blood samples and affected lymph node specimens from both dogs and revealed pyogranulomatous lymphadenitis in both dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2007 journal article

Doxycycline Clearance of Experimentally Induced Chronic Ehrlichia Canis Infection in Dogs

Journal of Veterinary Internal Medicine, 21(6), 1237–1242.

By: S. Eddlestone*, P. Diniz n, T. Neer*, S. Gaunt*, R. Corstvet*, D. Cho*, G. Hosgood*, B. Hegarty n, E. Breitschwerdt n

author keywords: canine ehrlichiosis; immunofluorescence assay; platelets; polymerase chain reaction
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Chronic Disease; Dog Diseases / drug therapy; Dogs; Doxycycline / therapeutic use; Ehrlichia canis; Ehrlichiosis / drug therapy; Ehrlichiosis / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2007 journal article

Evaluation of conventional and real-time PCR assays for detection and differentiation of Spotted Fever Group Rickettsia in dog blood

Veterinary Microbiology, 129(3-4), 294–303.

By: L. Kidd n, R. Maggi n, P. Diniz n, B. Hegarty n, M. Tucker n & E. Breitschwerdt n

author keywords: dog; PCR; Rickettsia; spotted fever
MeSH headings : Animals; Bacterial Outer Membrane Proteins / genetics; Base Sequence; Boutonneuse Fever / diagnosis; Boutonneuse Fever / microbiology; Boutonneuse Fever / veterinary; DNA Primers; DNA, Bacterial / blood; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Disease Reservoirs / veterinary; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Gene Amplification; Humans; Molecular Sequence Data; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Rickettsia / classification; Rickettsia / genetics; Rickettsia / isolation & purification; Rickettsia conorii / classification; Rickettsia conorii / genetics; Rickettsia conorii / isolation & purification; Rickettsia rickettsii / classification; Rickettsia rickettsii / genetics; Rickettsia rickettsii / isolation & purification; Rocky Mountain Spotted Fever / diagnosis; Rocky Mountain Spotted Fever / microbiology; Rocky Mountain Spotted Fever / veterinary; Sensitivity and Specificity; Sentinel Surveillance / veterinary; Species Specificity
TL;DR: Conventional and real-time PCR assays developed using primers that targeted a small region of the ompA gene may assist in the timely diagnosis of infection with SFGRickettsia and facilitate the discovery of novel SFG Rickettsia infecting dogs, and in the investigation of dogs as sentinels for emerging rickettsioses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2007 journal article

Identification of bacteria from clinical samples using Bartonella alpha-Proteobacteria growth medium

Journal of Microbiological Methods, 71(2), 147–155.

By: M. Cadenas n, R. Maggi n, P. Diniz n, K. Breitschwerdt n, S. Sontakke* & E. Breithschwerdt n

author keywords: co-infection; fastidious bacteria; insect growth medium
MeSH headings : Animals; Bacteria / classification; Bacteria / growth & development; Bacteria / isolation & purification; Bacterial Infections / microbiology; Bacteriological Techniques / methods; Base Sequence; Culture Media / chemistry; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Bacterial / isolation & purification; DNA, Ribosomal / chemistry; DNA, Ribosomal / genetics; DNA, Ribosomal / isolation & purification; Humans; Molecular Sequence Data; Phylogeny; Polymerase Chain Reaction; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA; Sequence Homology, Nucleic Acid
TL;DR: Despite the phylogenetic limitations of using partial 16S rRNA gene sequencing for species and strain identification, the investigational methodology described in this study may provide a complementary approach for the isolation and identification of bacteria from patient samples. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2007 conference paper

Pathogens in rhipicephalus sanguineus infested dogs from the southwestern united states

Journal of Veterinary Internal Medicine, 21(3), 625.

By: P. Diniz, M. Beall, R. Chandrashekarl, D. Daniluk, K. Cyr, J. Koterski, R. Robbins, P. Konialestewa, B. Hegarty, E. Breitschwerdt

Event: 25th Annual American College of Veterinary Internal Medicine Forum at Seattle, WA on June 6-9, 2007

Source: NC State University Libraries
Added: March 23, 2021

2007 conference paper

Potentiation of thrombocytopenia and anemia in dogs experimentally coinfected with anaplasma platys and ehrlichia canis

Journal of Veterinary Internal Medicine, 21(3), 576.

By: S. Gaunt, C. Ramaswamy, M. Beall, K. Caterina & E. Breitschwerdt

Event: 25th Annual American College of Veterinary Internal Medicine Forum at Seattle, WA on June 6-9, 2007

Source: NC State University Libraries
Added: March 23, 2021

2007 conference paper

Preliminary evaluation of a peptide-based assay for detection of ehrlichia ewingh antibodies in experimentally and naturally-infected dogs

Journal of Veterinary Internal Medicine, 21(3), 625.

By: D. Daniluk, J. Shiuenwhite, T. O'Connor, M. Yabsley, D. Adams, P. Diniz, E. Breitschwerdt, S. Gaunt, R. Chandrashekar

Event: 25th Annual American College of Veterinary Internal Medicine Forum at Seattle, WA on June 6-9, 2007

Source: NC State University Libraries
Added: March 23, 2021

2007 journal article

Prevalence of Ehrlichia canis, Anaplasma platys, Babesia canis vogeli, Hepatozoon canis, Bartonella vinsonii berkhoffii, and Rickettsia spp. in dogs from Grenada

VETERINARY PARASITOLOGY, 151(2-4), 279–285.

By: M. Yabsley*, J. McKibben*, C. Macpherson*, P. Cattan*, N. Cherry n, B. Hegarty n, E. Breitschwerdt n, T. O'Connor* ...

author keywords: Anaplasma; Babesia; Bartonella; dog; Ehrlichia; Hepatozoon; Rickettsia; Rhipicephalus sanguineus
MeSH headings : Animals; Antibodies, Bacterial / blood; Antibodies, Protozoan / blood; Babesia / isolation & purification; Babesiosis / epidemiology; Babesiosis / veterinary; Coccidia / isolation & purification; Coccidiosis / epidemiology; Coccidiosis / veterinary; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Female; Gram-Negative Bacteria / isolation & purification; Gram-Negative Bacterial Infections / diagnosis; Gram-Negative Bacterial Infections / epidemiology; Gram-Negative Bacterial Infections / veterinary; Grenada / epidemiology; Male; Polymorphism, Single Nucleotide; Prevalence; RNA, Ribosomal, 16S / genetics; RNA, Ribosomal, 18S / genetics; Rhipicephalus sanguineus / microbiology; Rhipicephalus sanguineus / parasitology; Tick-Borne Diseases / diagnosis; Tick-Borne Diseases / epidemiology; Tick-Borne Diseases / veterinary
TL;DR: Results of this study indicate that dogs from Grenada are infected with multipletick-borne pathogens; therefore, tick-borne diseases should be included as differentials for dogs exhibiting thrombocytopenia, leukopenia, fever, or lethargy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2007 journal article

Science, medicine, academia, and the future of the ACVIM

Journal of Veterinary Internal Medicine, 21(3), 364–366.

By: J. Toll* & E. Breitschwerdt n

Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2007 journal article

Severe Anemia, Panserositis, and Cryptogenic Hepatitis in an HIV Patient Infected withBartonella henselae

Ultrastructural Pathology, 31(6), 373–377.

By: P. Velho*, V. Pimentel*, G. Negro*, T. Okay*, P. Diniz n & E. Breitschwerdt n

author keywords: anemia; Bartonella henselae; hepatitis; liver transplantation; serositis
MeSH headings : AIDS-Related Opportunistic Infections / drug therapy; AIDS-Related Opportunistic Infections / microbiology; AIDS-Related Opportunistic Infections / pathology; Adult; Anemia / drug therapy; Anemia / microbiology; Anemia / pathology; Angiomatosis, Bacillary / drug therapy; Angiomatosis, Bacillary / microbiology; Angiomatosis, Bacillary / pathology; Anti-Bacterial Agents / therapeutic use; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Base Sequence; Clarithromycin / therapeutic use; DNA, Bacterial / analysis; Erythrocytes / microbiology; Erythrocytes / ultrastructure; HIV Infections / microbiology; Hepatitis / drug therapy; Hepatitis / microbiology; Hepatitis / pathology; Humans; Immunocompromised Host; Male; Microscopy, Electron, Transmission / methods; Molecular Sequence Data; Serositis / drug therapy; Serositis / microbiology; Serositis / pathology; Skin Diseases / drug therapy; Skin Diseases / microbiology; Skin Diseases / pathology; Treatment Outcome
TL;DR: The case of an AIDS patient with bacillary angiomatosis, who had concurrent severe anemia, hepatitis, peritonitis, pleuritis, and pericarditis, is reported, which suggested a Bartonella sp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2007 journal article

Surveillance for Zoonotic Vector-Borne Infections Using Sick Dogs from Southeastern Brazil

Vector-Borne and Zoonotic Diseases, 7(4), 689–698.

By: P. Diniz n, D. Schwartz*, H. de Morais* & E. Breitschwerdt n

MeSH headings : Animals; Antibodies, Bacterial / blood; Antibodies, Protozoan / blood; Bartonella / isolation & purification; Bartonella / physiology; Bartonella Infections / blood; Bartonella Infections / epidemiology; Brazil / epidemiology; DNA, Bacterial / blood; Dog Diseases / blood; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Ehrlichia canis / genetics; Ehrlichia canis / isolation & purification; Ehrlichia canis / physiology; Ehrlichiosis / blood; Ehrlichiosis / epidemiology; Female; Leishmania infantum / isolation & purification; Leishmania infantum / physiology; Leishmaniasis, Visceral / blood; Leishmaniasis, Visceral / epidemiology; Male; Molecular Sequence Data; RNA, Ribosomal, 16S / genetics; Sentinel Surveillance; Sequence Alignment; Zoonoses / epidemiology
TL;DR: Ehrlichia canis may pose a human health hazard and may be undiagnosed in southeastern Brazil, whereas exposure to the other organisms examined in this study is presumably infrequent. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2006 journal article

A Bartonella vinsonii berkhoffii typing scheme based upon 16S–23S ITS and Pap31 sequences from dog, coyote, gray fox, and human isolates

Molecular and Cellular Probes, 20(2), 128–134.

By: R. Maggi n, B. Chomel*, B. Hegarty n, J. Henn* & E. Breitschwerdt n

author keywords: Bartonella; bacteria; canine; pathogen; classification; genes
MeSH headings : Animals; Bacterial Typing Techniques; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / genetics; Base Sequence; Coyotes / microbiology; DNA, Intergenic / genetics; DNA, Intergenic / isolation & purification; Disease Reservoirs; Dogs / microbiology; Foxes / microbiology; Humans; Molecular Sequence Data; Sequence Homology, Nucleic Acid; Viral Proteins / genetics
TL;DR: Strain typing may help to better define the reservoir potential, carriership patterns, modes of transmission, and geographic distribution for each B. vinsonii berkhoffii type in future molecular epidemiological studies involving Bartonella infection in coyotes, dogs, gray foxes, human beings and potentially other animals or in arthropod vectors. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2006 journal article

A serological study of exposure to arthropod-borne pathogens in dogs from northeastern Spain

VETERINARY RESEARCH, 37(2), 231–244.

By: L. Solano-Gallego n, J. Llull*, M. Osso, B. Hegarty n & E. Breitschwerdt n

author keywords: rickettsial pathogens; dogs; Spain
MeSH headings : Animal Husbandry / methods; Animals; Antibodies, Bacterial / blood; Antibodies, Protozoan / blood; Bacterial Infections / blood; Bacterial Infections / epidemiology; Bacterial Infections / veterinary; Dog Diseases / blood; Dog Diseases / epidemiology; Dogs; Female; Male; Protozoan Infections, Animal / blood; Protozoan Infections, Animal / epidemiology; Seasons; Seroepidemiologic Studies; Sex Factors; Spain / epidemiology; Tick-Borne Diseases / blood; Tick-Borne Diseases / epidemiology; Tick-Borne Diseases / veterinary; Ticks / microbiology; Ticks / parasitology
TL;DR: This study indicates that exposure to Rc, Li, Ec or related Ehrlichia spp, Bh and Ap or a related spp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 journal article

Alpha1-proteinase inhibitor deficiency and Bartonella infection in association with panniculitis, polyarthritis, and meningitis in a dog

Journal of Veterinary Internal Medicine, 20(4), 1023–1028.

By: P. Mellor, K. Fetz, R. Maggi, S. Haugland, M. Dunning, E. Villiers, R. Mellanby, D. Williams, E. Breitschwerdt, M. Herrtage

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Anaplasma spp, babesia canis, bartonella henselae, bartonella vinsonii subsp berkhoffii, borrelia burgdorferi, dirofilaria immitis, and ehrlichia canis seroprevalences in brazilian dogs

Journal of Veterinary Internal Medicine, 20(3), 712–713.

By: P. Diniz, D. Schwartz, R. Machado, J. Bradley, B. Hegarty & E. Breitschwerdt

Source: NC State University Libraries
Added: April 2, 2021

2006 journal article

Bartonella quintana Endocarditis in Dogs

Emerging Infectious Diseases, 12(12), 1869–1872.

By: P. Kelly*, J. Rolain, R. Maggi*, S. Sontakke*, B. Keene*, S. Hunter, H. Lepidi, K. Breitschwerdt ...

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bartonella Infections / drug therapy; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella quintana / growth & development; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Endocarditis, Bacterial / drug therapy; Endocarditis, Bacterial / microbiology; Endocarditis, Bacterial / veterinary; Fatal Outcome; Male
TL;DR: PCR and sequencing provide the first evidence that B. quintana can be pathogenic in dogs, according to a large number of animal studies. (via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries, Crossref
Added: August 6, 2018

2006 journal article

Bartonella spp. antigen recognition patterns in cats with and without fever

Journal of Veterinary Internal Medicine, 20(3), 710.

By: M. Lappin, J. Hawley & E. Breitschwerdt

Source: NC State University Libraries
Added: April 2, 2021

2006 journal article

BartonellaSpp. in Pets and Effect on Human Health

Emerging Infectious Diseases, 12(3), 389–394.

By: B. Chomel*, H. Boulouis*, S. Maruyama* & E. Breitschwerdt n

MeSH headings : Animals; Animals, Domestic / microbiology; Bartonella / classification; Bartonella / isolation & purification; Bartonella / physiology; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Disease Reservoirs / microbiology; Disease Reservoirs / veterinary; Humans; Insect Vectors / microbiology; Zoonoses / epidemiology; Zoonoses / microbiology; Zoonoses / transmission
TL;DR: Pets represent a large reservoir for human infection and can be a source of infection for humans and animals alike. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2006 journal article

Borrelia burgdorferi and anaplasma phagocytophilum: Potential implications of co-infection on clinical presentation in the dog

Journal of Veterinary Internal Medicine, 20(3), 713–714.

By: M. Beall, R. Chandrashekar, M. Eberts, K. Cyr, P. Diniz, C. Mainville, B. Hegarty, J. Crawford, E. Breitschwerdt

Source: NC State University Libraries
Added: April 2, 2021

2006 journal article

Comparison of an indirect immunofluorescence assay, western blot analysis, and a commercially available ELISA for detection ofEhrlichia canisantibodies in canine sera

American Journal of Veterinary Research, 67(2), 206–210.

By: T. O'Connor*, J. Hanscom n, B. Hegarty n, R. Groat n & E. Breitschwerdt n

MeSH headings : Animals; Antibodies, Bacterial / blood; Blotting, Western / veterinary; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / immunology; Dogs; Ehrlichia canis / immunology; Ehrlichia canis / isolation & purification; Ehrlichiosis / blood; Ehrlichiosis / diagnosis; Ehrlichiosis / immunology; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay / veterinary; Fluorescent Antibody Technique, Indirect / veterinary
TL;DR: The discrepancy between E canis-IFA, WB analyses, and the commercially available ELISA results for the low-titer serum samples may be related to a high IFA sensitivity or, more likely, a lack of specificity associated with cross-reactivity among Ehrlichia spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2006 journal article

Cytauxzoon felisinfection in cats in the mid-Atlantic states: 34 cases (1998–2004)

Journal of the American Veterinary Medical Association, 228(4), 568–571.

By: A. Birkenheuer n, J. Le*, A. Valenzisi*, M. Tucker*, M. Levy* & E. Breitschwerdt*

MeSH headings : Animals; Base Sequence; Cat Diseases / diagnosis; Cat Diseases / epidemiology; Cats; Diagnosis, Differential; Female; Geography; Male; North Carolina / epidemiology; Piroplasmida / isolation & purification; Piroplasmida / pathogenicity; Protozoan Infections, Animal / diagnosis; Protozoan Infections, Animal / epidemiology; RNA, Protozoan / genetics; RNA, Ribosomal / genetics; RNA, Ribosomal, 18S / genetics; Retrospective Studies; Seasons; Sequence Homology, Nucleic Acid; South Carolina / epidemiology; Virginia / epidemiology
TL;DR: Data indicate that veterinarians in the mid-Atlantic region of the United States should consider C. felis infection in cats that become ill with fever, icterus, and pancytopenia or bicy topenia, especially in the spring and summer months. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2006 journal article

Development and evaluation of a PCR assay for the detection of Cytauxzoon felis DNA in feline blood samples

VETERINARY PARASITOLOGY, 137(1-2), 144–149.

By: A. Birkenheuer n, H. Marr n, A. Alleman*, M. Levy n & E. Breitschwerdt n

author keywords: cytauxzoonosis; piroplasmosis; pancytopenia
MeSH headings : Animals; Blood / parasitology; Cat Diseases / blood; Cat Diseases / diagnosis; Cat Diseases / mortality; Cat Diseases / parasitology; Cats; DNA, Protozoan / analysis; Ixodidae / parasitology; Piroplasmida / genetics; Piroplasmida / isolation & purification; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Protozoan Infections, Animal / blood; Protozoan Infections, Animal / diagnosis; Protozoan Infections, Animal / mortality; Protozoan Infections, Animal / parasitology; RNA, Ribosomal, 18S / analysis; Sensitivity and Specificity
TL;DR: This work has developed and evaluated the sensitivity and specificity of a polymerase chain reaction (PCR) based assay and can be used for the rapid clinical diagnosis of cytauxzoonosis and for epidemiological studies that will better define the geographic distribution of C. felis infection in cats. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2006 journal article

Failure of imidocarb dipropionate to clear experimentally induced Ehrlichia canis infection in dogs

Journal of Veterinary Internal Medicine, 20(4), 840–844.

By: S. Eddlestone, T. Neer, S. Gaunt, R. Corstvet, A. Gill, G. Hosgood, B. Hegarty, E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Febrile Illness Associated with Rickettsia conorii Infection in Dogs from Sicily

Emerging Infectious Diseases, 12(12), 1985–1988.

By: L. Solano-Gallego*, L. Kidd*, M. Trotta, M. Di Marco, M. Caldin, T. Furlanello, E. Breitschwerdt*

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Antibodies, Bacterial / blood; Bacterial Outer Membrane Proteins / chemistry; Bacterial Outer Membrane Proteins / genetics; Base Sequence; Boutonneuse Fever / drug therapy; Boutonneuse Fever / microbiology; Boutonneuse Fever / veterinary; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Fever / microbiology; Fever / veterinary; Fluorescent Antibody Technique / veterinary; Male; Molecular Sequence Data; Polymerase Chain Reaction / veterinary; Rickettsia conorii / genetics; Rickettsia conorii / isolation & purification; Sequence Analysis, DNA; Sicily
TL;DR: Serologic and molecular evidence of acute, febrile illness associated with Rickettsia conorii in 3 male Yorkshire terriers from Sicily (Italy) is reported. (via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries, Crossref
Added: August 6, 2018

2006 journal article

Isolation of Bartonella quintana from a woman and a cat following putative bite transmission

JOURNAL OF CLINICAL MICROBIOLOGY, 45(1), 270–272.

By: E. Breitschwerdt n, R. Magi, B. Sigmon n & W. Nicholson*

MeSH headings : Adult; Animals; Bartonella quintana / classification; Bartonella quintana / genetics; Bartonella quintana / isolation & purification; Bites and Stings; Cat Diseases / microbiology; Cat Diseases / transmission; Cats; Female; Humans; Trench Fever / microbiology; Trench Fever / transmission
TL;DR: The detection of Bartonella quintana, after putative bite transmission, in pre-enrichment blood cultures from a woman and from two feral barn cats is reported. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 patent

Media and methods for cultivation of microorganisms

Washington, DC: U.S. Patent and Trademark Office.

By: E. Breitschwerdt & S. Sontakke

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Molecular Characterization of Rickettsia rickettsii Infecting Dogs and People in North Carolina

Annals of the New York Academy of Sciences, 1078(1), 400–409.

By: L. Kidd n, B. Hegarty n, D. Sexton* & E. Breitschwerdt n

author keywords: Rocky Mountain spotted fever; Rickettsia rickettsii; dog; gene sequence
MeSH headings : Animals; Base Sequence; Consensus Sequence; DNA Primers; Dog Diseases / microbiology; Dogs; Humans; Molecular Sequence Data; North Carolina / epidemiology; Rickettsia rickettsii / genetics; Rickettsia rickettsii / isolation & purification; Rocky Mountain Spotted Fever / epidemiology; Rocky Mountain Spotted Fever / veterinary
TL;DR: Describing rickettsial isolates obtained from three dogs and two persons diagnosed with RMSF in North Carolina confirms on a molecular level that R. ricksettsii causing naturally occurring R MSF in dogs in North North Carolina is highly homologous to R. Rickettsii that causes the disease in people in the same region. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 2, 2020

2006 journal article

Molecular characterization of a Babesia species identified in a North American raccoon

JOURNAL OF WILDLIFE DISEASES, 42(2), 375–380.

By: A. Birkenheuer n, J. Whittington*, J. Neel n, E. Large n, A. Barger*, M. Levy n, E. Breitschwerdt n

Contributors: A. Birkenheuer n, J. Whittington*, J. Neel n, E. Large n, A. Barger*, M. Levy n, E. Breitschwerdt n

author keywords: Babesia; PCR; phylogenetics; piroplasm; Procyon lotor; raccoon; taxonomy
MeSH headings : Animals; Babesia / classification; Babesia / isolation & purification; Babesiosis / epidemiology; Babesiosis / parasitology; Babesiosis / transmission; Babesiosis / veterinary; Diagnosis, Differential; Disease Reservoirs / veterinary; Gene Amplification; Humans; Male; Phylogeny; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; RNA, Protozoan / analysis; RNA, Ribosomal, 18S / analysis; Raccoons / parasitology; Zoonoses
TL;DR: The data generated in this study can be used to design molecular diagnostic tests for detection of this Babesia sp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2006 journal article

Molecular prevalence of bartonella spp. in brazilian dogs

Journal of Veterinary Internal Medicine, 20(3), 762.

By: P. Diniz, D. Schwartz, R. Maggi, M. Cadenas & E. Breitschwerdt

Source: NC State University Libraries
Added: April 2, 2021

2006 journal article

Serological and molecular evidence of exposure to arthropod-borne organisms in cats from northeastern Spain

VETERINARY MICROBIOLOGY, 118(3-4), 274–277.

By: L. Solano-Gallego n, B. Hegarty n, Y. Espada*, J. Llull & E. Breitschwerdt n

author keywords: Spain; cat; vector-borne pathogens; retrovirus
MeSH headings : Anaplasma phagocytophilum / immunology; Animals; Antibodies, Bacterial / blood; Antibodies, Viral / blood; Bartonella henselae / immunology; Cat Diseases / diagnosis; Cat Diseases / epidemiology; Cats; Cross Reactions; Diagnosis, Differential; Ehrlichia canis / immunology; Enzyme-Linked Immunosorbent Assay / methods; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Fluorescent Antibody Technique, Indirect / veterinary; Immunodeficiency Virus, Feline / immunology; Leukemia Virus, Feline / immunology; Male; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Rickettsia conorii / immunology; Seroepidemiologic Studies; Spain / epidemiology; Tick-Borne Diseases / diagnosis; Tick-Borne Diseases / epidemiology; Tick-Borne Diseases / veterinary; Ticks / microbiology; Ticks / virology
TL;DR: One hundred sixty-eight cat sera from Spain were tested for IgG antibodies to Rickettsia conorii (Rc), Ehrlichia canis (Ec), Anaplasma phagocytophilum (Ap) and Bartonella henselae (Bh) antigens using IFA and for FeLV antigen and FIV antibody by ELISA. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2006 journal article

The low seroprevalence of tick-transmitted agents of disease in dogs from southern Ontario and Quebec

Canadian Veterinary Journal, 47(12), 1194–1200.

By: A. Gary, J. Webb, B. Hegarty & E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2006 journal article

Use of an insect cell culture growth medium to isolate bacteria from horses with effusive, fibrinous pericarditis: A preliminary study

Veterinary Microbiology, 121(1-2), 177–181.

By: S. Jones n, A. Valenzisi n, S. Sontakke n, K. Sprayberry*, R. Maggi n, B. Hegarty n, E. Breitschwerdt n

author keywords: insect cell culture medium; mare reproductive loss syndrome; 16S rDNA; DNA sequencing
MeSH headings : Animals; Bacteria / genetics; Bacteria / isolation & purification; Bacterial Infections / microbiology; Bacterial Infections / pathology; Bacterial Infections / veterinary; Culture Media; Culture Techniques / veterinary; Disease Outbreaks / veterinary; Horse Diseases / microbiology; Horse Diseases / pathology; Horses; Insecta / cytology; Insecta / microbiology; Kentucky / epidemiology; Pericardial Effusion / microbiology; Pericardial Effusion / pathology; Pericarditis / microbiology; Pericarditis / pathology; Pericarditis / veterinary; Pilot Projects; Retrospective Studies
TL;DR: Bacterial isolation from equine pericardial fluid samples was attempted using an insect cell culture growth medium (ICCGM), but a similar or novel caterpillar-associated bacteria was not identified; however, use of an ICCGM might enhance isolation of bacteria from equines pericARDial fluid. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018

2006 journal article

Vector-borne diseases: What you don't know can kill you, your clients, or your patients

Compendium on Continuing Education for the Practicing Veterinarian, 28(3), 1–5.

By: E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Anaplasma phagocytophilum infection (granulocytic anaplasmosis) in a dog from Vancouver Island

Canadian Veterinary Journal, 46(9), 825–827.

By: S. Lester, E. Breitschwerdt, C. Collis & B. Hegarty

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Autochthonous visceral leishmaniasis in dogs in North America

Journal of the American Veterinary Medical Association, 226(8), 1316–1322.

By: P. Schantz n, F. Steurer n, Z. Duprey n, K. Kurpel n, S. Barr n, J. Jackson n, E. Breitschwerdt n, M. Levy n, J. Fox n

MeSH headings : Animals; Disease Outbreaks / veterinary; Disease Reservoirs / veterinary; Disease Transmission, Infectious / veterinary; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / transmission; Dogs; Fluorescent Antibody Technique, Indirect / veterinary; Humans; Leishmaniasis, Visceral / diagnosis; Leishmaniasis, Visceral / epidemiology; Leishmaniasis, Visceral / transmission; Leishmaniasis, Visceral / veterinary; North America / epidemiology; Polymerase Chain Reaction / veterinary
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2005 journal article

Bartonella Species as a Potential Cause of Epistaxis in Dogs

Journal of Clinical Microbiology, 43(5), 2529–2533.

By: E. Breitschwerdt n, B. Hegarty n, R. Maggi n, E. Hawkins n & P. Dyer*

MeSH headings : Animals; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; Base Sequence; DNA Primers; DNA, Bacterial / genetics; DNA, Bacterial / isolation & purification; Dog Diseases / microbiology; Dogs; Epistaxis / etiology; Epistaxis / microbiology; Epistaxis / veterinary; Female; Male
TL;DR: These cases, in conjunction with previously published reports, support a potential role for Bartonella spp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2005 journal article

Bartonella henselae and Rickettsia seroreactivity in a sick cat population from North Carolina

International Journal of Applied Research in Veterinary Medicine, 3(4), 287.

By: E. Breitschwerdt, J. Levine, S. Radulovic, S. Hanby, D. Kordick & K. Perle

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Bartonella henselae in porpoise blood

Emerging Infectious Diseases, 11(12), 1894–1898.

By: R. Maggi, C. Harms, A. Hohn, D. Pabst, W. McLellan, W. Walton, D. Rotstein, E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

Bartonella quintana in Cynomolgus Monkey (Macaca fascicularis)

Emerging Infectious Diseases, 11(12), 1931–1934.

By: L. O'Rourke*, C. Pitulle n, B. Hegarty n, S. Kraycirik*, K. Killary*, P. Grosenstein*, J. Brown n, E. Breitschwerdt n

MeSH headings : Animals; Bartonella quintana / classification; Bartonella quintana / genetics; Bartonella quintana / isolation & purification; Female; Macaca fascicularis / blood; Macaca fascicularis / microbiology; Phylogeny; Trench Fever / blood; Trench Fever / microbiology; Trench Fever / veterinary
TL;DR: This report describes naturally acquired B. quintana infection in a nonhuman primate. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2005 journal article

Clinicopathologic findings in dogs seroreactive toBartonella henselaeantigens

American Journal of Veterinary Research, 66(12), 2060–2064.

By: R. Goodman n & E. Breitschwerdt n

MeSH headings : Animals; Antigens, Bacterial / blood; Bartonella henselae / immunology; Bartonella henselae / pathogenicity; Disease Reservoirs / microbiology; Dog Diseases / immunology; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Odds Ratio; Serologic Tests / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2005 journal article

Detection of Medically Important Ehrlichia by Quantitative Multicolor TaqMan Real-Time Polymerase Chain Reaction of the dsb Gene

The Journal of Molecular Diagnostics, 7(4), 504–510.

By: C. Doyle*, M. Labruna*, E. Breitschwerdt n, Y. Tang*, R. Corstvet*, B. Hegarty n, K. Bloch*, P. Li*, D. Walker*, J. McBride*

MeSH headings : Animals; Color; Dogs; Ehrlichia / classification; Ehrlichia / enzymology; Ehrlichia / genetics; Ehrlichia / isolation & purification; Ehrlichiosis / blood; Ehrlichiosis / microbiology; Humans; Polymerase Chain Reaction / methods; Protein Disulfide Reductase (Glutathione) / genetics; Protein Disulfide Reductase (Glutathione) / metabolism; RNA, Ribosomal, 16S / genetics; Sensitivity and Specificity; Taq Polymerase / metabolism; Time Factors
TL;DR: The first tricolor TaqMan real-time polymerase chain reaction assay capable of simultaneously detecting and discriminating medically important ehrlichiae in a single reaction is developed, providing a powerful tool for prospective medical diagnosis for human and canine ehrlicioses and for ecologic and epidemiological studies involving arthropod and mammalian hosts. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 27, 2021

2005 journal article

Experimental Ehrlichia canis infection in the dog does not cause immunosuppression

VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, 109(1-2), 117–125.

By: P. Hess n, R. English n, B. Hegarty n, G. Brown n & E. Breitschwerdt n

author keywords: Ehrlichia canis; dog; immunoregulation; immunophenotype analysis; lymphocyte proliferation; LAK; CD8(+) T cell
MeSH headings : Animals; Antibody Formation / immunology; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / microbiology; Dog Diseases / immunology; Dog Diseases / microbiology; Dogs; Doxycycline / therapeutic use; Ehrlichia canis / genetics; Ehrlichia canis / immunology; Ehrlichiosis / blood; Ehrlichiosis / immunology; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Female; Flow Cytometry / veterinary; Immunity, Cellular / immunology; Immunodiffusion / veterinary; Immunoglobulins / blood; Immunophenotyping / veterinary; Killer Cells, Lymphokine-Activated / immunology; Random Allocation; Specific Pathogen-Free Organisms
TL;DR: It is suggested that immune responses are not grossly impaired in young dogs during the first several months following experimental E. canis infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Geographic distribution of babesiosis among dogs in the United States and association with dog bites: 150 cases (2000-2003)

Journal of the American Veterinary Medical Association, 227(6), 942–947.

By: A. Birkenheuer n, M. Correa, M. Levy* & E. Breitschwerdt*

MeSH headings : Animals; Babesia / classification; Babesia / isolation & purification; Babesiosis / epidemiology; Babesiosis / transmission; Babesiosis / veterinary; Bites and Stings / complications; Bites and Stings / veterinary; Breeding; DNA, Protozoan / analysis; Dog Diseases / epidemiology; Dog Diseases / transmission; Dogs; Geography; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Retrospective Studies; United States / epidemiology
TL;DR: Testing for babesiosis should be pursued in dogs with clinicopathologic abnormalities consistent with immune-mediated hemolytic anemia or thrombocytopenia, particularly if there is a history of a recent dog bite. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2005 journal article

Isolation of Bacteriophages from <i>Bartonella vinsonii </i>subsp.<i> berkhoffii</i> and the Characterization of Pap31 Gene Sequences from Bacterial and Phage DNA

Journal of Molecular Microbiology and Biotechnology, 9(1), 44–51.

By: R. Maggi n & E. Breitschwerdt*

author keywords: alpha-proteobacteria; virus; canine; pathogen; phage-associated protein; Bartonella
MeSH headings : Bacteriophages / genetics; Bacteriophages / isolation & purification; Bacteriophages / ultrastructure; Bartonella / virology; Base Sequence; Conserved Sequence; Genes, Viral; Microscopy, Electron; Molecular Sequence Data; Phylogeny; Sequence Homology, Amino Acid; Virion / ultrastructure
TL;DR: The detection and purification of a novel tailed bacteriophage from Bartonella vinsonii subsp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2005 journal article

Isolation of necrotoxigenic Escherichia coli from a dog with hemorrhagic pneumonia

Journal of the American Veterinary Medical Association, 226(12), 2016–2019.

By: E. Breitschwerdt n, C. DebRoy, A. Mexas n, T. Brown n & A. Remick n

MeSH headings : Animals; Bacterial Typing Techniques / veterinary; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Escherichia coli / isolation & purification; Escherichia coli / pathogenicity; Escherichia coli Infections / diagnosis; Escherichia coli Infections / microbiology; Escherichia coli Infections / veterinary; Fatal Outcome; Hemorrhage / diagnosis; Hemorrhage / microbiology; Hemorrhage / veterinary; Lung / microbiology; Lung / pathology; Male; Pneumonia, Bacterial / diagnosis; Pneumonia, Bacterial / microbiology; Pneumonia, Bacterial / veterinary; Virulence
TL;DR: A 7-month-old sexually intact male Cocker Spaniel was admitted to the North Carolina State University Veterinary Teaching Hospital for evaluation of lethargy, panting, and excessive salivation that had become progressively severe during a 5-hour period, and death was attributed to acute, severe, necrotizing pneumonia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2005 journal article

Novel Chemically Modified Liquid Medium That Will Support the Growth of Seven Bartonella Species

Journal of Clinical Microbiology, 43(6), 2651–2655.

By: R. Maggi n, A. Duncan n & E. Breitschwerdt n

MeSH headings : Angiomatosis, Bacillary / microbiology; Animals; Bacteriological Techniques; Bartonella / classification; Bartonella / growth & development; Bartonella / isolation & purification; Bartonella henselae / growth & development; Bartonella henselae / isolation & purification; Blood / microbiology; Cat Diseases / microbiology; Cats; Colony Count, Microbial; Culture Media / chemistry; Humans
TL;DR: A novel, chemically modified, insect-based liquid culture medium is described that supports the growth of at least seven Bartonella species and may provide an advantage over conventional direct blood agar plating for the diagnostic confirmation of bartonellosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: NC State University Libraries, NC State University Libraries, Crossref
Added: August 6, 2018

2005 journal article

Phylogenetic analysis of the spirochetes Borrelia parkeri and Borrelia turicatae and the potential for tick-borne relapsing fever in Florida

JOURNAL OF CLINICAL MICROBIOLOGY, 43(8), 3851–3859.

By: T. Schwan*, S. Raffel*, M. Schrumpf*, P. Policastro*, J. Rawlings*, R. Lane*, E. Breitschwerdt n, S. Porcella*

MeSH headings : Bacterial Proteins / analysis; Borrelia / classification; Borrelia / genetics; Humans; Phylogeny; Plasmids; Relapsing Fever / microbiology; Sequence Analysis, DNA
TL;DR: The Florida canine borrelia (FCB) was clearly separated with the group identified as B. turicatae, confirming this bacterium as a relapsing fever spirochete, and future efforts are needed to determine the enzootic hosts and distribution of this spiroChete in the southeastern United States. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2005 journal article

Potential Limitations of the 16S-23S rRNA Intergenic Region for Molecular Detection of Bartonella Species

Journal of Clinical Microbiology, 43(3), 1171–1176.

By: R. Maggi n & E. Breitschwerdt n

MeSH headings : Bartonella / genetics; Bartonella / isolation & purification; DNA Primers; DNA, Intergenic; Polymerase Chain Reaction / methods; RNA, Ribosomal, 16S / genetics; RNA, Ribosomal, 23S / genetics
TL;DR: The results define some potential limitations associated with the molecular detection of Bartonella species in patient samples and indicate that primer specificity is of critical importance if the ITS region is used as a diagnostic target for Detection of Bart onella species. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2005 personal communication

Potential limitations of the 16S-23S rRNA intergenic region for molecular detection of Bartonella species - Authors' reply

By: E. Breitschwerdt & R. Maggi

Source: NC State University Libraries
Added: August 6, 2018

2005 journal article

The Dog as a Sentinel for Human Infection: Prevalence of Borrelia burgdorferi C6 Antibodies in Dogs from Southeastern and Mid-Atlantic States

Vector-Borne and Zoonotic Diseases, 5(2), 101–109.

By: A. Duncan n, M. Correa n, J. Levine n & E. Breitschwerdt n

author keywords: Borrelia burgdorferi C6; dogs; lyme disease
MeSH headings : Animals; Antibodies, Bacterial / blood; Arachnid Vectors / microbiology; Borrelia burgdorferi / immunology; Carrier State / veterinary; Disease Reservoirs / veterinary; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Enzyme-Linked Immunosorbent Assay / veterinary; Humans; Ixodes / microbiology; Lyme Disease / epidemiology; Lyme Disease / microbiology; Lyme Disease / transmission; Maryland / epidemiology; North Carolina / epidemiology; Pennsylvania / epidemiology; Sentinel Surveillance; Seroepidemiologic Studies; Virginia / epidemiology; Zoonoses
TL;DR: The hypothesis that B. burgdorferi transmission seems to occur infrequently in North Carolina dogs as compared to dogs residing in other southeastern and mid-Atlantic states is supported and the utility of dogs as a sentinel to characterize the risk of B. Burgdorferis transmission to humans in a defined geographical location is supported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2004 journal article

Antinuclear antibodies can be detected in dog sera reactive to Bartonella vinsonii subsp berkhoffii, Ehrlichia canis, or Leishmania infantum antigens

JOURNAL OF VETERINARY INTERNAL MEDICINE, 18(1), 47–51.

By: B. Smith n, M. Tompkins* & E. Breitschwerdt*

author keywords: autoimmunity; systemic lupus erythematous
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 journal article

Bartonella henselae IgG antibodies are prevalent in dogs from southeastern USA

VETERINARY RESEARCH, 35(5), 585–595.

By: L. Solano-Gallego n, J. Bradley n, B. Hegarty n, B. Sigmon n & E. Breitschwerdt n

author keywords: Bartonella henselae; dog; serology; vector-borne diseases
MeSH headings : Angiomatosis, Bacillary / epidemiology; Angiomatosis, Bacillary / veterinary; Animals; Antibodies, Bacterial / analysis; Bartonella henselae / immunology; Bartonella henselae / isolation & purification; Case-Control Studies; Dog Diseases / epidemiology; Dog Diseases / etiology; Dogs; Female; Immunoglobulin G / immunology; Male; North Carolina / epidemiology; Seroepidemiologic Studies
TL;DR: This study indicates that B. henselae IgG antibodies are prevalent in healthy and sick dogs living in the south-eastern USA, and further studies are needed to evaluate the epidemiological, clinical and zoonotic relevance of B.Henselae infection in dogs. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 journal article

Cat scratch disease and other zoonoticBartonellainfections

Journal of the American Veterinary Medical Association, 224(8), 1270–1279.

By: B. Chomel, H. Boulouis* & E. Breitschwerdt*

MeSH headings : Aminoglycosides / therapeutic use; Animals; Anti-Bacterial Agents / therapeutic use; Bartonella / isolation & purification; Bartonella / pathogenicity; Bartonella Infections / epidemiology; Bartonella Infections / prevention & control; Bartonella Infections / transmission; Bartonella henselae / isolation & purification; Bartonella henselae / pathogenicity; Cat Diseases / epidemiology; Cat Diseases / prevention & control; Cat Diseases / transmission; Cat-Scratch Disease / epidemiology; Cat-Scratch Disease / prevention & control; Cat-Scratch Disease / transmission; Cats; Disease Reservoirs / veterinary; Dog Diseases / epidemiology; Dog Diseases / prevention & control; Dog Diseases / transmission; Dogs; Humans; Immunocompromised Host; Public Health; Zoonoses
TL;DR: Members of the genus Bartonella are maintained in many domesticated and wild animal hosts, and although these organisms have been implicated occasionally in illnesses, proving a causative role is difficult. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2004 journal article

Chronic canine ehrlichiosis (Ehrlichia canis): A retrospective study of 19 natural cases

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 40(3), 174–184.

By: M. Mylonakis n, A. Koutinas n, E. Breitschwerdt n, B. Hegarty n, C. Billinis n, L. Leontides n, V. Kontos n

MeSH headings : Animals; Antibodies, Bacterial / blood; Antigens, Bacterial / immunology; Blood Cell Count / veterinary; Chronic Disease / therapy; Dog Diseases / blood; Dog Diseases / mortality; Dog Diseases / pathology; Dogs; Ehrlichia canis / immunology; Ehrlichia canis / isolation & purification; Ehrlichiosis / blood; Ehrlichiosis / mortality; Ehrlichiosis / pathology; Ehrlichiosis / veterinary; Female; Fluorescent Antibody Technique, Indirect / methods; Fluorescent Antibody Technique, Indirect / veterinary; Male; Retrospective Studies; Seasons
TL;DR: Nineteen dogs from Greece with chronic ehrlichiosis were studied, and concurrent infections did not appear to substantially influence the clinical course and final outcome of the chronic canine ehrliciosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 journal article

Clinicopathological abnormalities and treatment response in 24 dogs seroreactive to Bartonella vinsonii (berkhoffii) antigens

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 40(2), 92–101.

By: E. Breitschwerdt n, K. Blann n, M. Stebbins n, K. Munana n, M. Davidson n, H. Jackson n, M. Willard n

Contributors: E. Breitschwerdt n, K. Blann n, M. Stebbins n, K. Muñana n, M. Davidson n, H. Jackson n, M. Willard n

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Antigens, Bacterial / cerebrospinal fluid; Antigens, Bacterial / immunology; Bartonella / immunology; Bartonella Infections / diagnosis; Bartonella Infections / drug therapy; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Diagnosis, Differential; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Female; Male; Retrospective Studies; Treatment Outcome
TL;DR: It is indicated that a diverse spectrum of disease manifestations and clinicopathological abnormalities can be detected in dogs that are seroreactive to B. vinsonii (berkhoffii) antigens. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2004 journal article

Comparison of results for serologic testing and a polymerase chain reaction assay to determine the prevalence of stray dogs in eastern Tennessee seropositive to Ehrlichia canis

American Journal of Veterinary Research, 65(9), 1200–1203.

By: R. Seaman*, S. Kania, B. Hegarty*, A. Legendre & E. Breitschwerdt*

MeSH headings : Animals; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Ehrlichia canis; Ehrlichiosis / epidemiology; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay / methods; Enzyme-Linked Immunosorbent Assay / veterinary; Fluorescent Antibody Technique, Indirect / methods; Fluorescent Antibody Technique, Indirect / veterinary; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Seroepidemiologic Studies; Serologic Tests / veterinary; Tennessee / epidemiology
TL;DR: The discordant ELISA, IFA, and PCR results obtained in this study were unexpected and may have been related to exposure of dogs to an Ehrlichia species other than E. canis, such as E. ewingii. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2004 journal article

Detection and molecular characterization of a novel large Babesia species in a dog

Veterinary Parasitology, 124(3-4), 151–160.

By: A. Birkenheuer n, J. Neel n, D. Ruslander n, M. Levy n & E. Breitschwerdt n

Contributors: A. Birkenheuer n, J. Neel n, D. Ruslander n, M. Levy n & E. Breitschwerdt n

author keywords: piroplasm; babesiosis; 18S; rRNA; taxonomy
MeSH headings : Animals; Antibodies, Protozoan / blood; Antiprotozoal Agents / therapeutic use; Babesia / classification; Babesia / genetics; Babesia / immunology; Babesia / isolation & purification; Babesiosis / drug therapy; Babesiosis / parasitology; Babesiosis / veterinary; Cross Reactions; Dog Diseases / drug therapy; Dog Diseases / parasitology; Dogs; Female; Fluorescent Antibody Technique, Indirect / veterinary; Imidocarb / therapeutic use; Phylogeny; Polymerase Chain Reaction / veterinary; RNA, Ribosomal, 18S; Sequence Homology, Nucleic Acid; Treatment Outcome
TL;DR: The molecular characterization of a large Babesia species that was detected in the blood and bone marrow of a dog with clinical and hematological abnormalities consistent with babesiosis is described. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2004 article

Efficacy of combined atovaquone and azithromycin for therapy of chronic Babesia gibsoni (Asian genotype) infections in dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 18, pp. 494–498.

By: A. Birkenheuer n, M. Levy n & E. Breitschwerdt n

author keywords: piroplasm; polymerase chain reaction; protozoa; treatment
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2004 journal article

Molecular and serologic evidence of Anaplasma phagocytophilum infection in cats in North America

Journal of the American Veterinary Medical Association, 225(6), 893–896.

By: M. Lappin*, E. Breitschwerdt*, W. Jensen, B. Dunnigan, J. Rha, C. Williams, M. Brewer, M. Fall

MeSH headings : Anaplasma phagocytophilum / genetics; Anaplasma phagocytophilum / immunology; Anaplasma phagocytophilum / isolation & purification; Animals; Anti-Bacterial Agents / therapeutic use; Antibodies, Bacterial / blood; Cat Diseases / blood; Cat Diseases / drug therapy; Cat Diseases / epidemiology; Cats; DNA, Bacterial / analysis; Doxycycline / therapeutic use; Ehrlichiosis / blood; Ehrlichiosis / drug therapy; Ehrlichiosis / epidemiology; Ehrlichiosis / veterinary; Female; Fever of Unknown Origin / blood; Fever of Unknown Origin / drug therapy; Fever of Unknown Origin / veterinary; Ixodes / microbiology; Male; Polymerase Chain Reaction / veterinary; Seroepidemiologic Studies; Thrombocytopenia / blood; Thrombocytopenia / drug therapy; Thrombocytopenia / veterinary; Tick Infestations / epidemiology; Tick Infestations / veterinary; Treatment Outcome
TL;DR: Results suggest that infection with the organism may be associated with clinical illness in some cats, and this is the first report of A. phagocytophilum infection of domestic cats in North America. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2004 journal article

ORCHITIS IN TWO DOGS WITH ROCKY MOUNTAIN SPOTTED FEVER

Veterinary Radiology & Ultrasound, 45(5), 458–465.

By: C. Ober n, K. Spaulding n, E. Breitschwerdt n, D. Malarkey* & B. Hegarty n

author keywords: orchitis; rickettsia; testicle; ultrasound
MeSH headings : Animals; Diagnosis, Differential; Dog Diseases / diagnostic imaging; Dogs; Male; Orchitis / complications; Orchitis / diagnostic imaging; Orchitis / veterinary; Rocky Mountain Spotted Fever / complications; Rocky Mountain Spotted Fever / veterinary; Ultrasonography
TL;DR: Two dogs with testicular swelling were sonographically diagnosed with orchitis and were subsequently diagnosed with Rocky Mountain spotted fever (RMSF) and should be considered in any dog with vascular insult to the testes, especially when other signs of systemic illness are involved. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2004 journal article

Prevalence of infectious diseases in feral cats in Northern Florida

Journal of Feline Medicine and Surgery, 6(5), 287–296.

By: B. Luria*, J. Levy*, M. Lappin*, E. Breitschwerdt n, A. Legendre*, J. Hernandez*, S. Gorman*, I. Lee*

MeSH headings : Animals; Animals, Wild; Bacterial Infections / epidemiology; Bacterial Infections / microbiology; Bacterial Infections / veterinary; Bartonella henselae / isolation & purification; Cat Diseases / blood; Cat Diseases / epidemiology; Cat Diseases / microbiology; Cat Diseases / virology; Cats; Female; Florida / epidemiology; Immunodeficiency Virus, Feline / isolation & purification; Leukemia Virus, Feline / isolation & purification; Male; Mycoplasma / isolation & purification; Polymerase Chain Reaction / veterinary; Prevalence; Retroviridae Infections / epidemiology; Retroviridae Infections / veterinary; Retroviridae Infections / virology
TL;DR: Feral cats assessed in this study appear to be of no greater risk to human beings or other cats than pet cats, and had similar or lower prevalence rates of infections than those published for pet cats in the United States. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2004 journal article

Seroprevalences of antibodies against Bartonella henselae and Toxoplasma gondii and fecal shedding of Cryptosporidium spp, Giardia spp, and Toxocara catiin feral and pet domestic cats

Journal of the American Veterinary Medical Association, 225(9), 1394–1398.

By: F. Nutter n, J. Dubey n, J. Levine n, E. Breitschwerdt n, R. Ford n & M. Stoskopf n

MeSH headings : Animals; Animals, Domestic; Animals, Wild; Antibodies, Bacterial / blood; Antibodies, Protozoan / blood; Bartonella henselae / immunology; Cat Diseases / epidemiology; Cat-Scratch Disease / epidemiology; Cat-Scratch Disease / veterinary; Cats; Feces / microbiology; Feces / parasitology; Female; Male; Seroepidemiologic Studies; Toxoplasma / immunology; Toxoplasmosis, Animal / epidemiology
TL;DR: Feral cats did have higher seroprevalences of antibodies against B. henselae and T. gondii than did pet cats, but this likely was related to greater exposure to vectors of these organisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2004 journal article

The Clinician Investigator Program in Companion Animal Internal Medicine at North Carolina State University

Journal of Veterinary Medical Education, 31(4), 425–434.

By: S. Bunch n, R. Ford*, E. Hawkins*, M. Jackson*, S. Vaden* & E. Breitschwerdt*

MeSH headings : Animals; Animals, Domestic; Curriculum; Education, Veterinary / methods; Humans; Internal Medicine / education; Mentors; North Carolina; Research Personnel; Retrospective Studies; Schools, Veterinary; Surveys and Questionnaires
TL;DR: A retrospective study was conducted to describe the development and evolution of the combined internal medicine/PhD program, the Clinician Investigator (CI) Program, at North Carolina State University. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: NC State University Libraries, NC State University Libraries, Crossref
Added: August 6, 2018

2004 journal article

The Dog as a Sentinel for Human Infection: Prevalence of Borrelia burgdorferi C6 Antibodies in Dogs from Southeastern and Mid-Atlantic States

Vector-Borne and Zoonotic Diseases, 4(3), 221–229.

By: A. Duncan n, M. Correa n, J. Levine n & E. Breitschwerdt n

author keywords: Lyme disease; Borrelia burgdorferi; dog; North Carolina
MeSH headings : Animals; Antibodies, Bacterial / blood; Borrelia burgdorferi / immunology; Carrier State / veterinary; Disease Reservoirs / veterinary; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Enzyme-Linked Immunosorbent Assay; Lyme Disease / epidemiology; Lyme Disease / microbiology; Lyme Disease / transmission; Maryland / epidemiology; North Carolina / epidemiology; Pennsylvania / epidemiology; Sentinel Surveillance; Seroepidemiologic Studies; Virginia / epidemiology; Zoonoses
TL;DR: The hypothesis that B. burgdorferi transmission seems to occur infrequently in North Carolina dogs as compared to dogs residing in other southeastern and mid-Atlantic states is supported and the utility of dogs as a sentinel to characterize the risk of B. Burgdorferis transmission to humans in a defined geographical location is supported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2003 journal article

Acute nontraumatic hemoabdomen in the dog: A retrospective analysis of 39 cases (1987-2001)

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 39(6), 518–522.

By: J. Pintar n, E. Breitschwerdt n, E. Hardie n & K. Spaulding n

MeSH headings : Abdominal Cavity; Anemia / etiology; Anemia / veterinary; Animals; Ascites / blood; Ascites / etiology; Ascites / surgery; Ascites / veterinary; Dog Diseases / diagnosis; Dog Diseases / mortality; Dog Diseases / surgery; Dogs; Emergency Medical Services / methods; Female; Hemangiosarcoma / complications; Hemangiosarcoma / mortality; Hemangiosarcoma / surgery; Hemangiosarcoma / veterinary; Hypoalbuminemia / etiology; Hypoalbuminemia / veterinary; Male; Peritoneum; Retrospective Studies; Survival Analysis; Treatment Outcome
TL;DR: The medical records of 39 dogs with acute nontraumatic hemoabdomen were identified and reviewed and malignant neoplasia was diagnosed most frequently and occurred in 24/30 (80%) dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2003 journal article

Bartonella vinsonii subspecies berkhoffi as a possible cause of anterior uveitis and choroiditis in a dog

VETERINARY OPHTHALMOLOGY, 6(4), 299–304.

By: T. Michau n, E. Breitschwerdt n, B. Gilger n & M. Davidson n

author keywords: anterior uveitis; Bartonella vinsonii; canine; choroiditis
MeSH headings : Animals; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; Choroiditis / diagnosis; Choroiditis / veterinary; Diagnosis, Differential; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Female; Uveitis, Anterior / diagnosis; Uveitis, Anterior / veterinary
TL;DR: This is the first reported case of a possible association between uveitis, choroiditis and Bartonella infection in the dog, without clinical manifestations of other organ or tissue involvement. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2003 journal article

Capnocytophaga sp. Isolated from a Cat with Chronic Sinusitis and Rhinitis

Journal of Clinical Microbiology, 41(11), 5321–5324.

By: E. Frey n, B. Pressler n, J. Guy n, C. Pitulle n & E. Breitschwerdt n

MeSH headings : Animals; Capnocytophaga / genetics; Capnocytophaga / isolation & purification; Capnocytophaga / pathogenicity; Cat Diseases / diagnosis; Cat Diseases / microbiology; Cats; Cell Line; DNA Primers; Gram-Negative Bacterial Infections / diagnosis; Gram-Negative Bacterial Infections / veterinary; Kidney / microbiology; Kidney / pathology; Kidney / ultrastructure; Male; Molecular Sequence Data; Orchiectomy; Polymerase Chain Reaction; Rhinitis / veterinary; Sinusitis / veterinary; Zoonoses
TL;DR: A Capnocytophaga sp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2003 journal article

Characterization of the Major Antigenic Protein 2 of Ehrlichia canis and Ehrlichia chaffeensis and Its Application for Serodiagnosis of Ehrlichiosis

Clinical and Diagnostic Laboratory Immunology, 10(4), 520–524.

By: T. Knowles n, A. Alleman n, H. Sorenson n, D. Marciano n, E. Breitschwerdt n, S. Harrus n, A. Barbet n, M. Belanger n

MeSH headings : Amino Acid Sequence; Animals; Antigens, Bacterial / genetics; Antigens, Bacterial / immunology; Arkansas / epidemiology; Bacterial Proteins; Cross Reactions; Disease Reservoirs; Dog Diseases / diagnosis; Dog Diseases / immunology; Dogs; Ehrlichia canis / genetics; Ehrlichia canis / immunology; Ehrlichia chaffeensis / genetics; Ehrlichia chaffeensis / immunology; Ehrlichiosis / diagnosis; Ehrlichiosis / epidemiology; Ehrlichiosis / immunology; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay; Florida / epidemiology; Genes, Bacterial; Humans; Molecular Sequence Data; North Carolina / epidemiology; Recombinant Fusion Proteins / immunology; Sequence Alignment; Sequence Homology, Amino Acid; Serologic Tests / methods; Species Specificity; Virginia / epidemiology
TL;DR: Genomic Southern blot analysis using digoxigenin-labeled species-specific probes suggested that map2 is a single-copy gene in both Ehrlichia species, but ELISA and Western blot analysis confirmed that the E. chaffeensis rMAP2 failed to serologically differentiate between E. canis and E. Chaffeensis infections. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 27, 2021

2003 journal article

Characterization of the major antigenic protein 2 of Ehrlichia canis and Ehrlichia chaffeensis and its application for serodiagnosis of ehrlichiosis

Clinical and Diagnostic Laboratory Immunology, 10(4), 520–524.

By: T. Knowles, A. Alleman, H. Sorenson, D. Marciano, E. Breitschwerdt, S. Harrus, A. Barbet, M. Belanger

Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2003 journal article

Clinical Impact of PersistentBartonellaBacteremia in Humans and Animals

Annals of the New York Academy of Sciences, 990(1), 267–278.

By: B. Chomel*, R. Kasten*, J. Sykes*, H. Boulouis* & E. Breitschwerdt n

author keywords: Bartonella; vector-borne pathogens; bacteremia
MeSH headings : Animals; Animals, Wild; Bacteremia / physiopathology; Bacteremia / veterinary; Bartonella Infections / epidemiology; Bartonella Infections / physiopathology; Bartonella Infections / veterinary; Cat Diseases / microbiology; Cat Diseases / physiopathology; Cats; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / physiopathology; Dogs; Humans; Rodent Diseases / microbiology; Rodent Diseases / physiopathology; Rodentia; United States / epidemiology
TL;DR: Bartonella spp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2003 journal article

Concurrent bartonellosis and babesiosis in a dog with persistent thrombocytopenia

Journal of the American Veterinary Medical Association, 223(9), 1306–1310.

By: A. Tuttle n, A. Birkenheuer*, T. Juopperi*, M. Levy* & E. Breitschwerdt*

MeSH headings : Animals; Antibodies, Protozoan / blood; Antiprotozoal Agents / therapeutic use; Babesia / genetics; Babesia / immunology; Babesia / isolation & purification; Babesiosis / complications; Babesiosis / diagnosis; Babesiosis / veterinary; Bartonella Infections / complications; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; DNA, Protozoan / blood; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / etiology; Dogs; Imidocarb / analogs & derivatives; Imidocarb / therapeutic use; Male; Polymerase Chain Reaction / veterinary; Thrombocytopenia / etiology; Thrombocytopenia / veterinary
TL;DR: Polymerase chain reaction (PCR) analysis of multiple stored blood samples obtained during the 5-month period of persistent thrombocytopenia identified DNA of B. canis vogeli. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: August 6, 2018

2003 journal article

Detection of Bartonella henselae and Bartonella clarridgeiae DNA in hepatic specimens from two dogs with hepatic disease

Journal of the American Veterinary Medical Association, 222(1), 47–51.

By: T. Gillespie*, R. Washabau*, M. Goldschmidt*, J. Cullen n, A. Rogala n & E. Breitschwerdt n

MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; DNA, Bacterial / analysis; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Female; Liver / microbiology; Liver / pathology; Liver Diseases / diagnosis; Liver Diseases / microbiology; Liver Diseases / pathology; Liver Diseases / veterinary; Polymerase Chain Reaction / veterinary
TL;DR: Identification of Bartonella DNA in these dogs indicates the need for future prospective studies to determine the clinical relevance of Bart onella spp infection in dogs with hepatic disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2003 journal article

Development and Evaluation of a Seminested PCR for Detection and Differentiation of Babesia gibsoni (Asian Genotype) and B. canis DNA in Canine Blood Samples

Journal of Clinical Microbiology, 41(9), 4172–4177.

By: A. Birkenheuer n, M. Levy n & E. Breitschwerdt*

MeSH headings : Animals; Babesia / genetics; Babesia / isolation & purification; Babesiosis / diagnosis; Babesiosis / veterinary; DNA, Protozoan / blood; Dog Diseases / diagnosis; Dogs; Polymerase Chain Reaction / methods; RNA, Ribosomal, 18S / chemistry; RNA, Ribosomal, 18S / genetics; Sensitivity and Specificity
TL;DR: The seminested PCR test was able to detect and discriminate B. gibsoni (Asian genotype), B.Canis subsp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2003 journal article

Emerging and re-emerging infectious diseases

Veterinary Clinics of North America: Small Animal Practice, 33(4), xi-xiii.

By: D. Macintire* & E. Breitschwerdt n

UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2003 journal article

Molecular identification of Ehrlichia ewingii infection in dogs: 15 cases (1997-2001)

JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 222(8), 1102–1107.

By: R. Goodman n, E. Hawkins*, N. Olby*, C. Grindem*, B. Hegarty* & E. Breitschwerdt*

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; DNA, Bacterial / blood; DNA, Bacterial / chemistry; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Doxycycline / therapeutic use; Ehrlichia / genetics; Ehrlichia / isolation & purification; Ehrlichiosis / diagnosis; Ehrlichiosis / drug therapy; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Female; Fever / microbiology; Fever / veterinary; Lameness, Animal / microbiology; Male; Polymerase Chain Reaction / methods; Polymerase Chain Reaction / veterinary; Retrospective Studies; Thrombocytopenia / microbiology; Thrombocytopenia / veterinary; Treatment Outcome
TL;DR: PCR testing for E ewingii infection should be considered in dogs with fever, neutrophilic polyarthritis, unexplained ataxia or paresis, thrombocytopenia, or unexplained reactive lymphocytes, and indogs with clinical signs suggestive of ehrlichiosis that are seronegative for E canis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2003 journal article

Serosurvey of antiBabesia antibodies in stray dogs and American pit bull terriers and American Staffordshire terriers from North Carolina

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 39(6), 551–557.

By: A. Birkenheuer n, M. Levy n, M. Stebbins n, M. Poore n & E. Breitschwerdt n

MeSH headings : Animals; Antibodies, Protozoan / blood; Babesia / immunology; Babesia / isolation & purification; Babesiosis / epidemiology; Babesiosis / veterinary; DNA, Protozoan / analysis; Dog Diseases / epidemiology; Dogs; Female; Male; North Carolina / epidemiology; Seroepidemiologic Studies
TL;DR: There was no association between antiBabesia antibodies and the presence of ticks, and there are currently Babesia gibsoni epizootics affecting American pit bull terrier kennels. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2003 journal article

The Immunologic Response of Dogs to Bartonella Vinsonii Subspecies Berkhoffii Antigens: as Assessed by Western Immunoblot Analysis

Journal of Veterinary Diagnostic Investigation, 15(4), 349–354.

By: E. Breitschwerdt n, J. Suksawat*, B. Chomel* & B. Hegarty n

MeSH headings : Animals; Antigens, Viral / analysis; Bartonella / immunology; Bartonella / pathogenicity; Bartonella Infections / immunology; Bartonella Infections / veterinary; Blotting, Western / veterinary; Diagnosis, Differential; Dog Diseases / immunology; Dog Diseases / microbiology; Dogs; Sensitivity and Specificity
TL;DR: The results of this study indicate that WI using agar-grown or cell culture–grown B. vinsonii (berkhoffii) antigens produce identical patterns of antigenic protein recognition. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2003 journal article

Transfusion-associated Babesia gibsoni infection in a dog

Journal of the American Veterinary Medical Association, 222(7), 959–963.

By: J. Stegeman*, A. Birkenheuer n, J. Kruger & E. Breitschwerdt n

MeSH headings : Animals; Antibodies, Protozoan / analysis; Antiprotozoal Agents / therapeutic use; Babesia / immunology; Babesiosis / diagnosis; Babesiosis / drug therapy; Babesiosis / etiology; Babesiosis / veterinary; Blood Transfusion / veterinary; Carrier State / diagnosis; Carrier State / parasitology; Carrier State / veterinary; DNA, Protozoan / isolation & purification; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / etiology; Dogs; Female; Fluorescent Antibody Technique / veterinary; Hematocrit / veterinary; Hysterectomy / veterinary; Ovariectomy / veterinary; Polymerase Chain Reaction / veterinary; Splenomegaly / parasitology; Splenomegaly / veterinary; Transfusion Reaction; Treatment Outcome
TL;DR: A series of antiparasitic treatments failed to eliminate the B gibsoni infection and screening of potential blood donor dogs for Babesia spp is becoming increasingly important in the United States. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2003 journal article

Transmission times and prevention of tick-borne diseases in dogs

Compendium on Continuing Education for the Practicing Veterinarian, 25(10), 742-.

By: L. Kidd & E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2003 journal article

Vector-borne diseases: From infectivity to control - A roundtable discussion

Veterinary Medicine, 98(10), 14-.

By: L. Austgen, T. Clekis, J. Mccall, M. Dryden & E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Bartonella henselae and Bartonella elizabethae as Potential Canine Pathogens

Journal of Clinical Microbiology, 40(12), 4670–4674.

By: A. Mexas n, S. Hancock n & E. Breitschwerdt n

MeSH headings : Animals; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonella / pathogenicity; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella henselae / classification; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Bartonella henselae / pathogenicity; Blood Specimen Collection / methods; DNA, Bacterial / blood; Dog Diseases / microbiology; Dogs; Edetic Acid; Female; Male; Polymerase Chain Reaction; Sequence Analysis, DNA
TL;DR: DNA from EDTA-anticoagulated blood samples obtained from four dogs was amplified and sequenced and showed that B. elizabethae should be added to the list of Bartonella species, and may have potential zoonotic implications, particularly if dogs can serve as a previously unrecognized reservoir for B. henselae. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2002 journal article

Coinfection with Three Ehrlichia Species in Dogs from Thailand and Venezuela with Emphasis on Consideration of 16S Ribosomal DNA Secondary Structure

Journal of Clinical Microbiology, 40(10), 3887–3887.

By: J. Suksawat n, C. Pitulle n, C. Arraga-Alvarado n, K. Madrigal n, S. Hancock n & E. Breitschwerdt n

Sources: Crossref, NC State University Libraries
Added: September 2, 2020

2002 journal article

Comparison of Serological Detection Methods for Diagnosis of Ehrlichia canis Infections in Dogs

Journal of Clinical Microbiology, 40(9), 3506–3508.

By: M. Belanger, H. Sorenson*, M. France*, M. Bowie, A. Barbet, E. Breitschwerdt n, A. Alleman*

MeSH headings : Animals; Antibodies, Bacterial / blood; Antigens, Bacterial / genetics; Antigens, Bacterial / immunology; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Ehrlichia / immunology; Ehrlichiosis / diagnosis; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay; Fluorescent Antibody Technique, Indirect; Recombinant Proteins / immunology; Reproducibility of Results; Sensitivity and Specificity; Serologic Tests
TL;DR: The value of four serological assays for the diagnosis of canine monocytic ehrlichiosis was determined by comparing them to the indirect fluorescent-antibody assay “gold standard” by finding the specificity of Dip-S-Ticks was significantly lower than that of all of the other tests evaluated. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2002 journal article

Consensus statement on ehrlichial disease of small animals from the infectious disease study group of the ACVIM

JOURNAL OF VETERINARY INTERNAL MEDICINE, 16(3), 309–315.

By: T. Neer*, E. Breitschwerdt*, R. Greene & M. Lappin

UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2002 journal article

Differentiation of Haemobartonella canis and Mycoplasma haemofelis on the basis of comparative analysis of gene sequences

American Journal of Veterinary Research, 63(10), 1385–1388.

By: A. Birkenheuer n, E. Breitschwerdt n, A. Alleman n & C. Pitulle n

MeSH headings : Anaplasmataceae / classification; Anaplasmataceae / genetics; Anaplasmataceae Infections / microbiology; Anaplasmataceae Infections / veterinary; Animals; Base Sequence; Cat Diseases / microbiology; Cats; DNA, Ribosomal / genetics; Dog Diseases / microbiology; Dogs; Mycoplasma / classification; Mycoplasma / genetics; Mycoplasma Infections / microbiology; Mycoplasma Infections / veterinary; Phylogeny; Ribonucleases / genetics; Species Specificity
TL;DR: Haemobartonella canis and M haemofelis are not identical organisms and molecular differentiation is more clearly evident by use of comparative analysis of RNase P gene sequences than by comparativeAnalysis of 16S rDNA gene sequences. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2002 journal article

Feline ehrlichiosis. The genetic identification of the agent in Avo cats

Pratique Medicale Et Chirurgicale De L'Animal De Compagnie, 37(3), 235–238.

By: J. Beaufils, E. Breitschwerdt, S. Hancock, B. Hegarty, J. Martin-Granel, P. Jumelle, M. Barbault-Jumelle, A. Blavier

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

Imaging of Pheochromocytoma in 2 dogs using p-[18F] Fluorobenzylguanidine

Veterinary Radiology and Ultrasound, 43(2), 183–186.

By: C. Berry n, T. Degrado*, F. Nutter n, P. Garg*, E. Breitschwerdt n, K. Spaulding n, K. Concannon n, M. Zalutsky*, R. Edward Coleman*

author keywords: canine; p-[F-18]fluorobenzylguanidine; pheochromocytoma
MeSH headings : Animals; Dog Diseases / diagnostic imaging; Dogs; Female; Fluorine Radioisotopes / metabolism; Pheochromocytoma / diagnostic imaging; Pheochromocytoma / veterinary; Tomography, Emission-Computed
TL;DR: The results indicate that [18F]PFBG may be useful for imaging canine pheochromocytomas and aid in differentiating adrenal masses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2002 journal article

Investigation of the phylogenetic relationships within the genus Bartonella based on comparative sequence analysis of the rnpB gene, 16S rDNA and 23S rDNA

INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY, 52(2002 Nov), 2075–2080.

By: C. Pitulle*, C. Strehse, J. Brown & E. Breitschwerdt

author keywords: 16S rDNA; 23S rDNA; RNase P RNA; phylogeny; genus Bartonella
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2002 journal article

Investigation of the phylogenetic relationships within the genus Bartonella based on comparative sequence analysis of the rnpB gene, 16S rDNA and 23S rDNA.

International Journal of Systematic and Evolutionary Microbiology, 52(6), 2075–2080.

By: C. Pitulle, C. Strehse, J. Brown & E. Breitschwerdt*

MeSH headings : Algorithms; Bartonella / classification; Bartonella / enzymology; Bartonella / genetics; Bartonella / pathogenicity; Base Sequence; DNA, Bacterial / genetics; DNA, Ribosomal / genetics; Endoribonucleases / genetics; Genes, Bacterial; Humans; Molecular Sequence Data; Phylogeny; RNA, Bacterial / genetics; RNA, Catalytic / genetics; RNA, Ribosomal, 16S / genetics; RNA, Ribosomal, 23S / genetics; Ribonuclease P; Sequence Homology, Nucleic Acid; Species Specificity
TL;DR: An alignment containing the sequences of three important phylogenetic markers, RNase P RNA, 16S rRNA and 23S r RNA, merged by catenation, is analysed to determine the phylogenetic relationships within the genus Bartonella. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 2, 2020

2002 journal article

Isolation and identification of Mycobacterium kansasii from pleural fluid of a dog with persistent pleural effusion

Journal of the American Veterinary Medical Association, 220(9), 1336–1340.

By: B. Pressler n, E. Hardie*, C. Pitulle*, R. Hopwood, S. Sontakke* & E. Breitschwerdt*

MeSH headings : Animals; Base Sequence; DNA, Bacterial / analysis; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Fatal Outcome; Female; Lung / surgery; Mycobacterium Infections, Nontuberculous / diagnosis; Mycobacterium Infections, Nontuberculous / microbiology; Mycobacterium Infections, Nontuberculous / veterinary; Mycobacterium kansasii / classification; Mycobacterium kansasii / genetics; Mycobacterium kansasii / isolation & purification; Pleural Effusion / diagnosis; Pleural Effusion / microbiology; Pleural Effusion / veterinary; Polymerase Chain Reaction / veterinary; Recurrence
TL;DR: This is the first report of M. kansasii infection in a dog, and one of few reports of antemortem mycobacterial isolation from a body fluid, as opposed to identification in specimens during histologic examination. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2002 article

Molecular evidence supporting Ehrlichia canis-like infection in cats

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 16, pp. 642–649.

By: E. Breitschwerdt n, A. Abrams-Ogg*, M. Lappin*, D. Bienzle*, S. Hancock n, S. Cowan n, J. Clooten*, B. Hegarty n, E. Hawkins n

author keywords: antinuclear antibodies; leukemia; polyarthritis; thrombocytopenia
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2002 journal article

Naturally OccurringEhrlichia chaffeensisInfection in Two Prosimian Primate Species: Ring-tailed Lemurs (Lemur catta) and Ruffed Lemurs (Varecia variegata)

Emerging Infectious Diseases, 8(12), 1497–1500.

By: C. Williams*, J. Van Steenhouse, J. Bradley n, S. Hancock n, B. Hegarty n & E. Breitschwerdt n

MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Disease Outbreaks / veterinary; Doxycycline / therapeutic use; Ehrlichia chaffeensis / isolation & purification; Ehrlichiosis / blood; Ehrlichiosis / drug therapy; Ehrlichiosis / veterinary; Lemur; North Carolina; Polymerase Chain Reaction
TL;DR: A naturally occurring infection of Ehrlichia chaffeensis in lemurs is described and Organisms were cultured from the blood of one lemur exhibiting clinical and hematologic abnormalities similar to those of humans infected with E. Chaffeensis. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2002 journal article

Single-Tube Nested PCR for Detection of Tritrichomonasfoetus in Feline Feces

Journal of Clinical Microbiology, 40(11), 4126–4130.

By: J. Gookin n, A. Birkenheuer*, E. Breitschwerdt* & M. Levy n

MeSH headings : Animals; Cat Diseases / diagnosis; Cat Diseases / parasitology; Cats; DNA Primers; DNA, Protozoan / analysis; DNA, Ribosomal / analysis; Feces / parasitology; Polymerase Chain Reaction / instrumentation; Polymerase Chain Reaction / methods; Protozoan Infections / diagnosis; Protozoan Infections / parasitology; Protozoan Infections, Animal; RNA, Ribosomal, 5.8S / genetics; Sensitivity and Specificity; Tritrichomonas foetus / genetics; Tritrichomonas foetus / isolation & purification
TL;DR: The results demonstrate that the single-tube nested PCR is ideally suited for diagnostic testing of feline fecal samples that are found negative by direct microscopy and culturing and definitive identification of microscopically observable or cultivated organisms. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2002 journal article

Visceral leishmaniasis in a New York foxhound kennel

JOURNAL OF VETERINARY INTERNAL MEDICINE, 16(1), 34–44.

By: A. Gaskin n, P. Schantz*, J. Jackson*, A. Birkenheuer n, L. Tomlinson n, M. Gramiccia*, M. Levy n, F. Steurer* ...

author keywords: canine; dogs; Leishmania; sand fly
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2001 journal article

Assessing the association between the geographic distribution of deer ticks and seropositivity rates to various tick-transmitted disease organisms in dogs

Journal of the American Veterinary Medical Association, 218(7), 1092–1097.

By: V. Hinrichsen, U. Whitworth, E. Breitschwerdt*, B. Hegarty* & T. Mather

MeSH headings : Animals; Antibodies, Bacterial / blood; Antibodies, Bacterial / immunology; Arachnid Vectors / microbiology; Arachnid Vectors / physiology; Bartonella / immunology; Bartonella Infections / epidemiology; Bartonella Infections / transmission; Bartonella Infections / veterinary; Borrelia burgdorferi Group / immunology; Deer; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Ehrlichia / immunology; Ehrlichiosis / epidemiology; Ehrlichiosis / transmission; Ehrlichiosis / veterinary; Fluorescent Antibody Technique, Indirect / methods; Fluorescent Antibody Technique, Indirect / veterinary; Ixodes / microbiology; Ixodes / physiology; Lyme Disease / epidemiology; Lyme Disease / transmission; Lyme Disease / veterinary; Rhode Island / epidemiology; Rickettsia rickettsii / immunology; Rocky Mountain Spotted Fever / epidemiology; Rocky Mountain Spotted Fever / transmission; Rocky Mountain Spotted Fever / veterinary; Seroepidemiologic Studies; Tick-Borne Diseases / epidemiology; Tick-Borne Diseases / transmission; Tick-Borne Diseases / veterinary
TL;DR: Information concerning tick distributions may be useful in predicting the pattern of disease associated with particular tick species and may aid diagnostic, prevention, and control efforts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2001 journal article

Canine Rocky Mountain spotted fever: A retrospective study of 30 cases

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 37(1), 41–48.

By: A. Gasser n, A. Birkenheuer* & E. Breitschwerdt*

MeSH headings : Animals; Antibodies, Bacterial / blood; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dogs; Female; Male; North Carolina / epidemiology; Records / veterinary; Retrospective Studies; Rickettsia rickettsii / immunology; Rocky Mountain Spotted Fever / epidemiology; Rocky Mountain Spotted Fever / veterinary
TL;DR: Dogs with antibody titers of 1:1,024 or greater at the time of presentation had a higher incidence of more severe neurological dysfunction and cutaneous lesions and the survival rate following R. rickettsii infection was 100%. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

2001 journal article

Coinfection with Three Ehrlichia Species in Dogs from Thailand and Venezuela with Emphasis on Consideration of 16S Ribosomal DNA Secondary Structure

Journal of Clinical Microbiology, 39(1), 90–93.

By: J. Suksawat n, C. Pitulle n, C. Arraga-Alvarado*, K. Madrigal*, S. Hancock n & E. Breitschwerdt n

MeSH headings : Animals; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Ribosomal / chemistry; DNA, Ribosomal / genetics; Dog Diseases / microbiology; Dogs; Ehrlichia / classification; Ehrlichia / genetics; Ehrlichia / isolation & purification; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Molecular Sequence Data; Nucleic Acid Conformation; Phylogeny; Polymerase Chain Reaction / methods; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA; Species Specificity; Thailand; Venezuela
TL;DR: These results provide the first molecular documentation for the presence of E. platys 16S ribosomal DNA (rDNA) sequences reported from these two geographically divergent countries, and a phylogenetic analysis of the rRNA, incorporating the consideration of secondary structure. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2001 journal article

Differentiation of Ehrlichia platys and E. equi Infections in Dogs by Using 16S Ribosomal DNA-Based PCR

Journal of Clinical Microbiology, 39(12), 4577–4578.

By: S. Hancock n, E. Breitschwerdt n & C. Pitulle n

MeSH headings : Animals; DNA Primers; DNA, Ribosomal / analysis; Dog Diseases / microbiology; Dogs; Ehrlichia / classification; Ehrlichia / genetics; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Polymerase Chain Reaction / methods; RNA, Ribosomal, 16S / genetics
TL;DR: New PCR primers for the identification of E. equi and E. platys organisms are designed and tested and found to have previously unrecognized specificity problem when using small-subunit ribosomal DNA (16S rDNA) based primers. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2001 journal article

Experimental infection of cats with Tritrichomonas foetus

American Journal of Veterinary Research, 62(11), 1690–1697.

By: J. Gookin n, M. Levy*, J. Law*, M. Papich*, M. Poore* & E. Breitschwerdt*

MeSH headings : Animals; Antigens, Protozoan / analysis; Antiprotozoal Agents / administration & dosage; Antiprotozoal Agents / therapeutic use; Cat Diseases / drug therapy; Cat Diseases / parasitology; Cats; Cryptosporidiosis / complications; Cryptosporidiosis / drug therapy; Cryptosporidiosis / veterinary; Cryptosporidium / growth & development; Diarrhea / drug therapy; Diarrhea / parasitology; Diarrhea / veterinary; Feces / parasitology; Female; Intestinal Diseases / drug therapy; Intestinal Diseases / parasitology; Intestinal Diseases / veterinary; Intestinal Mucosa / parasitology; Nitro Compounds; Parasite Egg Count / veterinary; Prednisolone / administration & dosage; Prednisolone / therapeutic use; Protozoan Infections / complications; Protozoan Infections / drug therapy; Protozoan Infections, Animal; Specific Pathogen-Free Organisms; Thiazoles / administration & dosage; Thiazoles / therapeutic use; Tritrichomonas foetus
TL;DR: After experimental inoculation in cats, T. foetus organisms colonize the ileum, cecum, and colon, reside in close contact with the epithelium, and are associated with transient diarrhea that is exacerbated by coexisting cryptosporidiosis but not treatment with prednisolone. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2001 journal article

Immunodiagnosis of Ehrlichia canis Infection with Recombinant Proteins

Journal of Clinical Microbiology, 39(1), 315–322.

By: J. McBride*, R. Corstvet*, E. Breitschwerdt n & D. Walker*

MeSH headings : Amino Acid Sequence; Animals; Antibodies, Bacterial / blood; Antigens, Bacterial / chemistry; Antigens, Bacterial / genetics; Antigens, Bacterial / immunology; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Bacterial Proteins / immunology; Base Sequence; Blotting, Southern; Blotting, Western / methods; Cloning, Molecular; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Ehrlichia / immunology; Ehrlichiosis / diagnosis; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Fluorescent Antibody Technique, Indirect / methods; Molecular Sequence Data; Recombinant Proteins / immunology; Sequence Analysis, DNA
TL;DR: The results of this study demonstrate that the rP43 and rP28 are sensitive and reliable serodiagnostic antigens for E. canis infections. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2001 article

Immunopathology of Bartonella vinsonii (berkhoffii) in experimentally infected dogs

Pappalardo, B. L., Brown, T. T., Tompkins, M., & Breitschwerdt, E. B. (2001, December). VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, Vol. 83, pp. 125–147.

By: B. Pappalardo n, T. Brown n, M. Tompkins n & E. Breitschwerdt n

author keywords: dog; Bartonella; immunosuppression
MeSH headings : Animals; Antigen Presentation / immunology; Apoptosis / immunology; Bartonella / genetics; Bartonella / growth & development; Bartonella Infections / immunology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; CD4-CD8 Ratio; Cytokines / biosynthesis; Cytokines / blood; DNA, Bacterial / chemistry; DNA, Bacterial / isolation & purification; Dog Diseases / immunology; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Flow Cytometry / veterinary; Histocytochemistry; Lymph Nodes / immunology; Lymph Nodes / pathology; Lymphocytes / immunology; Phagocytosis / immunology; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Reverse Transcriptase Polymerase Chain Reaction / veterinary; Specific Pathogen-Free Organisms; T-Lymphocyte Subsets / immunology
TL;DR: Results from this study indicate that B. vinsonii establishes chronic infection in dogs which may result in immune suppression characterized by defects in monocytic phagocytosis, an impaired subset of CD8+ T lymphocytes, and impaired antigen presentation within LN. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2001 journal article

Infection of Fetal Feline Brain Cells in Culture with Bartonella henselae

Infection and Immunity, 69(1), 564–569.

By: K. Munana n, S. Vitek n, B. Hegarty n, D. Kordick n & E. Breitschwerdt n

Contributors: K. Muñana n, S. Vitek n, B. Hegarty n, D. Kordick n & E. Breitschwerdt n

MeSH headings : Animals; Astrocytes / microbiology; Bartonella henselae / physiology; Brain / cytology; Brain / microbiology; Brain Diseases / etiology; Cats; Cells, Cultured; DNA, Bacterial / analysis; Female; Fetus / microbiology; Microglia / microbiology; Microscopy, Electron; Pregnancy
TL;DR: A role for microglia in the pathogenesis of B. henselae-associated neurological disease is suggested, and evidence of infection was seen in Bartonella-inoculated astrocyte cultures. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2001 journal article

Infection with Bartonella weissii and Detection of Nanobacterium Antigens in a North Carolina Beef Herd

Journal of Clinical Microbiology, 39(3), 879–882.

By: E. Breitschwerdt n, S. Sontakke n, A. Cannedy n, S. Hancock n & J. Bradley n

MeSH headings : Alphaproteobacteria / isolation & purification; Animals; Antibodies, Bacterial / blood; Antigens, Bacterial / analysis; Bartonella / classification; Bartonella / genetics; Bartonella / immunology; Bartonella / isolation & purification; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Blood / microbiology; Cattle; Cattle Diseases / microbiology; Culture Media; Enzyme-Linked Immunosorbent Assay; Genes, rRNA / genetics; Meat / microbiology; Molecular Sequence Data; North Carolina; RNA, Ribosomal, 16S / genetics; Sequence Analysis, DNA
TL;DR: It is concluded that infection with an organism similar or closely related to Bartonella weissii can occur in North Carolina cattle and that although their actual existence is still controversial, nanobacterium antigens were detected with a commercially available test kit. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2001 journal article

Recombinant Major Antigenic Protein 2 of Ehrlichia canis: a Potential Diagnostic Tool

Journal of Clinical Microbiology, 39(7), 2494–2499.

By: A. Alleman, L. McSherry, A. Barbet*, E. Breitschwerdt n, H. Sorenson, M. Bowie*, M. Belanger*

MeSH headings : Animals; Antibodies, Bacterial / blood; Antigens, Bacterial / genetics; Antigens, Bacterial / immunology; Bacterial Proteins; Blotting, Western; Cloning, Molecular; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Ehrlichia / immunology; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay; Membrane Proteins / genetics; Membrane Proteins / immunology; Recombinant Proteins / immunology; Sequence Analysis, DNA
TL;DR: Data suggest that rMAP2 of E. canis could be used as a recombinant test antigen for the serodiagnosis of canine monocytic ehrlichiosis. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2001 journal article

Serologic and molecular evidence of coinfection with multiple vector-borne pathogens in dogs from Thailand

JOURNAL OF VETERINARY INTERNAL MEDICINE, 15(5), 453–462.

By: J. Suksawat*, X. Yu*, S. Hancock n, B. Hegarty n, P. Nilkumhang* & E. Breitschwerdt n

author keywords: canine; diseases; polymerase chain reaction; serology; ticks
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2001 journal article

Testing for tick-borne diseases in dogs - A roundtable discussion

Veterinary Technician, 22(4), 184–189.

By: R. Ford, M. Lappin, S. Levy, M. Philipp & E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2001 review

Tick-borne infectious diseases of dogs

[Review of ]. TRENDS IN PARASITOLOGY, 17(2), 74–80.

By: S. Shaw*, M. Day*, R. Birtles* & E. Breitschwerdt n

MeSH headings : Animals; Communicable Diseases, Emerging / veterinary; Disease Reservoirs; Dog Diseases / transmission; Dogs; Sentinel Surveillance; Tick Infestations / veterinary; Tick-Borne Diseases / etiology; Tick-Borne Diseases / veterinary
TL;DR: This work discusses the emergence of new canine tick-transmitted diseases, which results from several factors, including the expansion of the tick range into urban and semi-urban areas worldwide, the movement of infected dogs into previously non-endemic areas, and the advent of novel molecular techniques for diagnosis and pathogen identification. (via Semantic Scholar)
UN Sustainable Development Goal Categories
11. Sustainable Cities and Communities (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

Bartonella Infection in Animals: Carriership, Reservoir Potential, Pathogenicity, and Zoonotic Potential for Human Infection

Clinical Microbiology Reviews, 13(3), 428–438.

By: E. Breitschwerdt n & D. Kordick n

Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2000 chapter

Bartonella infections in domestic cats

In Kirk's current veterinary therapy : small animal practice (13th Ed.) (p. 302). Philadelphia, PA : W.B. Saunders.

By: D. Kordick & E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Bartonella spp Antibodies and DNA in Aqueous Humour of Cats

Journal of Feline Medicine and Surgery, 2(1), 61–68.

By: M. Lappin*, D. Kordick n & E. Breitschwerdt n

MeSH headings : Animals; Antibodies, Bacterial / analysis; Aqueous Humor / microbiology; Bartonella / genetics; Bartonella / immunology; Bartonella / isolation & purification; Bartonella Infections / immunology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Cat Diseases / immunology; Cat Diseases / microbiology; Cats; DNA, Bacterial / analysis; Enzyme-Linked Immunosorbent Assay / veterinary; Immunoglobulin G / analysis; Polymerase Chain Reaction / veterinary; Uveitis / immunology; Uveitis / microbiology; Uveitis / veterinary
TL;DR: Bartonella spp infect the eyes of some cats following natural exposure or experimental inoculation and may cause uveitis in some cats. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 2, 2020

2000 chapter

Bartonella vinsonii infection in dogs

In Kirk's current veterinary therapy : small animal practice (13th Ed.) (p. 300). Philadelphia, PA : W.B. Saunders.

By: B. Pappalardo & E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Coyotes (Canis latrans) as the reservoir for a human pathogenic Bartonella sp.: Molecular epidemiology of Bartonella vinsonii subsp berkhoffii infection in coyotes from central coastal California

Journal of Clinical Microbiology, 38(11), 4193–4200.

By: C. Chang, R. Kasten, B. Chomel, D. Simpson, C. Hew, D. Kordick, R. Heller, Y. Piemont, E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2000 article

Cyclic CD8+lymphopenia in dogs experimentally infected with Bartonella vinsonii subsp berkhoffii

Pappalardo, B. L., Brown, T., Gebhardt, D., Sontakke, S., & Breitschwerdt, E. B. (2000, June 30). VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY, Vol. 75, pp. 43–57.

By: B. Pappalardo n, T. Brown n, D. Gebhardt n, S. Sontakke n & E. Breitschwerdt n

author keywords: mAb, monoclonal antibody; FBS, fetal bovine serum; PID, post-inoculation day; PBL, peripheral blood lymphocytes; LN, lymph node
MeSH headings : Animals; Bartonella Infections / complications; Bartonella Infections / veterinary; CD4-CD8 Ratio; CD8-Positive T-Lymphocytes; Cell Separation / veterinary; Disease Models, Animal; Dog Diseases / blood; Dog Diseases / microbiology; Dogs; Flow Cytometry / veterinary; Leukocyte Count / veterinary; Lymphopenia / etiology; Lymphopenia / microbiology; Lymphopenia / veterinary; Polymerase Chain Reaction / veterinary
TL;DR: Evidence supporting a potentially important association between B. vinsonii and Ehrlichia canis co-infection in dogs is found based on a seroepidemiologic survey of dogs from North Carolina and Virginia presenting for a variety of medical problems. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

Familial glomerulonephropathy in a litter of Beagles

Journal of the American Veterinary Medical Association, 216(1), 46–50.

By: J. Rha*, M. Labato, L. Ross, E. Breitschwerdt* & J. Alroy

MeSH headings : Animals; Blood Chemical Analysis / veterinary; Dog Diseases / diagnosis; Dog Diseases / genetics; Dogs; Fatal Outcome; Female; Glomerulonephritis, Membranoproliferative / diagnosis; Glomerulonephritis, Membranoproliferative / genetics; Glomerulonephritis, Membranoproliferative / veterinary; Kidney / pathology; Kidney / ultrastructure; Male; Microscopy, Electron / veterinary; Proteinuria / veterinary
TL;DR: Families of Beagles raised in more than 1 area of the United States with similar clinicopathologic abnormalities, common genetic background, and identical histopathologic and electron microscopic findings, familial renal disease was diagnosed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2000 article

Granulomatous disease associated with Bartonella infection in 2 dogs

JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 14, pp. 37–42.

By: B. Pappalardo n, T. Brown*, J. Gookin n, C. Morrill n & E. Breitschwerdt n

author keywords: canine; infectious; lymphadenopathy; pathology
TL;DR: This is the 1st report of granulomatous disease in dogs associated with Bartonella infection, and an 11-year-old mixed-breed dog was referred for evaluation of a 6-week history of serous nasal discharge. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2000 journal article

Peliosis hepatis in a dog infected withBartonella henselae

Journal of the American Veterinary Medical Association, 216(4), 519–523.

By: B. Kitchell*, T. Fan*, D. Kordick n, E. Breitschwerdt n, G. Wollenberg* & C. Lichtensteiger*

MeSH headings : Animals; Ascitic Fluid / diagnostic imaging; Ascitic Fluid / surgery; Ascitic Fluid / veterinary; Bartonella Infections / complications; Bartonella Infections / veterinary; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Biopsy, Needle / veterinary; DNA, Bacterial / analysis; Dog Diseases / diagnostic imaging; Dog Diseases / microbiology; Dog Diseases / surgery; Dogs; Drainage / veterinary; Female; Liver / diagnostic imaging; Liver / microbiology; Liver / pathology; Peliosis Hepatis / microbiology; Peliosis Hepatis / surgery; Peliosis Hepatis / veterinary; Polymerase Chain Reaction / veterinary; Ultrasonography
TL;DR: To the authors' knowledge, this is the first report of molecular evidence of molecularevidence of B henselae infection in a dog with peliosis hepatis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2000 journal article

Prevalence of Bartonella henselae Antibody in Florida Panthers

Journal of Wildlife Diseases, 36(1), 157–160.

By: D. Rotstein*, S. Taylor*, J. Bradley n & E. Breitschwerdt n

author keywords: Bartonellosis; Bartonella henselae; Florida panther; mountain lion; Puma concolor coryi; Puma concolor stanleyana; serology
MeSH headings : Animals; Antibodies, Bacterial / blood; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Bartonella henselae / immunology; Carnivora; Female; Florida / epidemiology; Male; Seroepidemiologic Studies; Texas
TL;DR: Serum samples from 28 free-ranging Florida panthers and seven mountain lions living in south Florida between 1997 to 1998 were tested for antibodies to Bartonella henselae and the seroprevalence in animals <2-yr from southern Florida was similar to prevalences reported in mountain lions or domestic felids in California. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2000 journal article

Rapid identification and differentiation of Bartonella species using a single-step PCR assay

Journal of Clinical Microbiology, 38(5), 1717–1722.

By: W. Jensen, M. Fall, J. Rooney, D. Kordick & E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2000 journal article

Seroprevalence of Ehrlichia canis, Ehrlichia equi, and Ehrlichia risticii in sick dogs from North Carolina and Virginia

Journal of Veterinary Internal Medicine, 14(1), 50–55.

By: J. Suksawat n, B. Hegarty n & E. Breitschwerdt n

TL;DR: Ehrlichia canis, E. equi, and E. risticii seroprevalence was determined by microimmunofluorescent antibody testing in a sequential population of 1,845 sick dogs admitted during a 1-year period to the North Carolina State University Veterinary Teaching Hospital to indicate that ehrlichiosis was not diagnosed in the majority of serologically confirmed cases. (via Semantic Scholar)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2000 chapter

The rickettsioses

In Textbook of veterinary internal medicine : diseases of the dog and cat (5th Ed.) (p. 400). Philadelphia, PA : W.B. Saunders.

By: E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2000 chapter

Why are infectious diseases emerging?

In Kirk's current veterinary therapy : small animal practice (13th Ed.) (p. 244). Philadelphia, PA : W.B. Saunders.

By: E. Breitschwerdt & S. Dow

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

A retrospective study of ehrlichiosis in 62 dogs from North Carolina and Virginia

JOURNAL OF VETERINARY INTERNAL MEDICINE, 13(3), 194–201.

By: . Frank n & E. Breitschwerdt n

author keywords: Ehrlichia canis; response to therapy; infectious disease; flow cytometry
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1999 journal article

Babesia gibsoni infections in dogs from North Carolina

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 35(2), 125–128.

By: A. Birkenheuer n, M. Levy*, K. Savary, R. Gager & E. Breitschwerdt*

MeSH headings : Animals; Babesia / isolation & purification; Babesiosis / diagnosis; Babesiosis / epidemiology; Babesiosis / therapy; Diagnosis, Differential; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Female; Male; North Carolina / epidemiology
TL;DR: The recognition of canine babesiosis in North Carolina caused by Babesia gibsoni documents the expansion of the previously reported endemic area of this disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018

1999 journal article

Bartonella vinsonii subsp berkhoffi and related members of the alpha subdivision of the Proteobacteria in dogs with cardiac arrhythmias, endocarditis, or myocarditis

Journal of Clinical Microbiology, 37(11), 3618–3626.

By: E. Breitschwerdt, C. Atkins, T. Brown, D. Kordick & P. Snyder

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Clinical and pathologic evaluation of chronic Bartonella henselae or Bartonella clarridgeiae infection in cats

Journal of Clinical Microbiology, 37(5), 1536–1547.

By: D. Kordick, T. Brown, K. Shin & E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Coinfection with multiple tick-borne pathogens in a Walker Hound kennel in North Carolina

Journal of Clinical Microbiology, 37(8), 2631–2638.

By: S. Kordick, E. Breitschwerdt, B. Hegarty, K. Southwick, C. Colitz, S. Hancock, J. Bradley, R. Rumbough, J. McPherson, J. MacCormack

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Diarrhea associated with trichomonosis in cats

Journal of the American Veterinary Medical Association, 215(10), 1450–1454.

By: J. Gookin, E. Breitschwerdt, M. Ley, R. Gager & J. Benrud

Source: NC State University Libraries
Added: August 6, 2018

1999 journal article

Efficacy of Doxycycline, Azithromycin, or Trovafloxacin for Treatment of Experimental Rocky Mountain Spotted Fever in Dogs

Antimicrobial Agents and Chemotherapy, 43(4), 813–821.

By: E. Breitschwerdt*, M. Papich n, B. Hegarty*, B. Gilger*, S. Hancock & M. Davidson*

MeSH headings : Animals; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / therapeutic use; Anti-Infective Agents / blood; Anti-Infective Agents / therapeutic use; Azithromycin / blood; Azithromycin / therapeutic use; Capillary Permeability / drug effects; DNA, Bacterial / analysis; Dogs; Doxycycline / blood; Doxycycline / therapeutic use; Female; Fluoroquinolones; Guinea Pigs; Male; Naphthyridines / blood; Naphthyridines / therapeutic use; Polymerase Chain Reaction; Rickettsia rickettsii / drug effects; Rickettsia rickettsii / isolation & purification; Rocky Mountain Spotted Fever / drug therapy; Rocky Mountain Spotted Fever / immunology; Treatment Outcome
TL;DR: Doxycycline and trovafloxacin was as efficacious as doxycycline but azithromycin proved less efficacious, possibly due to the short duration of administration. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1999 journal article

Platelet-associated immunoglobulin (antiplatelet antibody) in canine Rocky Mountain spotted fever and ehrlichiosis

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 35(1), 56–61.

By: C. Grindem n, E. Breitschwerdt*, P. Perkins*, L. Cullins, T. Thomas & B. Hegarty*

MeSH headings : Animals; Antibodies, Bacterial / blood; Autoantibodies / blood; Blood Platelets / immunology; Dog Diseases / blood; Dog Diseases / immunology; Dogs; Ehrlichia / immunology; Ehrlichiosis / blood; Ehrlichiosis / immunology; Ehrlichiosis / veterinary; Flow Cytometry / veterinary; Fluorescent Antibody Technique, Indirect / veterinary; Immunoglobulin G / blood; Rickettsia rickettsii / immunology; Rocky Mountain Spotted Fever / blood; Rocky Mountain Spotted Fever / immunology; Rocky Mountain Spotted Fever / veterinary; Thrombocytopenia / blood; Thrombocytopenia / immunology; Thrombocytopenia / veterinary
TL;DR: Results of this study indicate an immunological component for rickettsial thrombocytopenia, and current therapeutic recommendations, especially regarding avoiding the use of immunosuppressive drugs in patients with ricksettsial diseases, need to be critically reviewed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1999 article

The incidence of ehrlichial and rickettsial infection in patients with unexplained fever and recent history of tick bite in central North Carolina

Carpenter, C. F., Gandhi, T. K., Kong, L. K., Corey, G. R., Chen, S. M., Walker, D. H., … al. (1999, September). JOURNAL OF INFECTIOUS DISEASES, Vol. 180, pp. 900–903.

By: C. Carpenter*, T. Gandhi*, L. Kong*, G. Corey*, S. Chen, D. Walker*, J. Dumler*, E. Breitschwerdt n ...

MeSH headings : Adult; Animals; Antibodies, Bacterial / blood; Comorbidity; Ehrlichia chaffeensis / isolation & purification; Ehrlichiosis / blood; Ehrlichiosis / epidemiology; Fever of Unknown Origin / blood; Fever of Unknown Origin / etiology; Fever of Unknown Origin / microbiology; Humans; Incidence; Insect Bites and Stings; Leukocyte Count; North Carolina / epidemiology; Platelet Count; Polymerase Chain Reaction; Rickettsia / isolation & purification; Rickettsia Infections / blood; Rickettsia Infections / epidemiology; Ticks
TL;DR: It is concluded that ehrlichial infections may be as common as spotted fever group rickettsial infections in febrile patients from central North Carolina with a recent history of tick bite. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1998 journal article

A survey of tick-borne bacteria and protozoa in naturally exposed dogs from Israel

VETERINARY PARASITOLOGY, 74(2-4), 133–142.

By: G. Baneth*, E. Breitschwerdt n, B. Hegarty n, B. Pappalardo n & J. Ryan n

author keywords: dog; Ehrlichia canis; Bartonella vinsonii; Babesia canis; Babesia gibsoni; Rickettsia conorii; Israel
MeSH headings : Animals; Animals, Domestic / microbiology; Animals, Domestic / parasitology; Antibodies, Bacterial / blood; Antibodies, Bacterial / immunology; Antibodies, Protozoan / blood; Antibodies, Protozoan / immunology; Babesia / immunology; Bacterial Infections / blood; Bacterial Infections / epidemiology; Bacterial Infections / veterinary; Bartonella / immunology; Blotting, Western / veterinary; Borrelia burgdorferi Group / immunology; Case-Control Studies; Data Collection; Dog Diseases / blood; Dog Diseases / epidemiology; Dogs; Ehrlichia / immunology; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Fluorescent Antibody Technique, Indirect / veterinary; Israel / epidemiology; Male; Prevalence; Protozoan Infections, Animal / blood; Protozoan Infections, Animal / epidemiology; Rickettsia / immunology; Tick-Borne Diseases / blood; Tick-Borne Diseases / epidemiology; Tick-Borne Diseases / veterinary; Ticks
TL;DR: Western blot analysis for antibodies reactive to B. burgdorferi identified genus-specific antiflagellin antibodies indicating that dogs in Israel are exposed to a Borrelia species, indicating that Lyme borreliosis in people in Israel is likely. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

1998 journal article

Doxycycline hyclate treatment of experimental canine ehrlichiosis followed by challenge inoculation with two Ehrlichia canis strains

Antimicrobial Agents and Chemotherapy, 42(2), 362–368.

By: E. Breitschwerdt, B. Hegarty & S. Hancock

Source: NC State University Libraries
Added: August 6, 2018

1998 journal article

Dual Infection with Ehrlichia chaffeensis and a Spotted Fever Group Rickettsia: A Case Report

Emerging Infectious Diseases, 4(2), 311–316.

By: D. Sexton*, G. Corey, C. Carpenter, L. Kong, T. Gandhi, E. Breitschwerdt, B. Hegarty, S. Chen ...

MeSH headings : Adult; Ehrlichia chaffeensis / genetics; Ehrlichia chaffeensis / isolation & purification; Ehrlichiosis / complications; Ehrlichiosis / diagnosis; Fluorescent Antibody Technique; Genes, Bacterial; Humans; Male; Polymerase Chain Reaction; Rickettsia rickettsii / isolation & purification; Rocky Mountain Spotted Fever / blood; Rocky Mountain Spotted Fever / complications; Rocky Mountain Spotted Fever / diagnosis; Sequence Analysis, DNA; Skin / microbiology
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1998 journal article

Granulocytic Ehrlichiosis in Dogs from North Carolina and Virginia

Journal of Veterinary Internal Medicine, 12(2), 61–70.

By: E. Goldman*, E. Breitschwerdt n, C. Grindem n, B. Hegarty*, J. Walls* & J. Dumler*

author keywords: anemia; polyarthritis; polymerase chain reaction; tick-transmitted rickettsia
MeSH headings : Animals; Dog Diseases; Dogs; Ehrlichia / classification; Ehrlichia / genetics; Ehrlichia / isolation & purification; Ehrlichiosis / blood; Ehrlichiosis / veterinary; Genes, Bacterial; Humans; Medical Records; Neutrophils / parasitology; North Carolina; Polymerase Chain Reaction; RNA, Ribosomal, 16S / genetics; Retrospective Studies; Virginia
TL;DR: Serologic or molecular results support the possibility of E. ewingii, E. equi, and E. canis coinfection or serologic cross-reactivity among canine granulocytic and monocytic Ehrlichia species in dogs from North Carolina and Virginia. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1998 journal article

Immunophenotypic Comparison of Blood and Lymph Node from Dogs with Lymphoma

Veterinary Clinical Pathology, 27(1), 16–20.

By: C. Grindem n, R. Page n, B. Ammerman n & E. Breitschwerdt n

author keywords: immunophenotyping; blood; bone marrow; lymph nodes; lymphoma; dogs
TL;DR: Simultaneous immunophenotyping of lymph node, blood and bone marrow cannot be recommended routinely without further studies to document its value as an independent prognostic indicator, however, it is potentially useful for tumor staging and monitoring remission, especially in lymphoma patients with a leukemic phase. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1998 journal article

Persistent Infection of Pets within a Household with Three Bartonella Species

Emerging Infectious Diseases, 4(2), 325–328.

By: D. Kordick n & E. Breitschwerdt*

MeSH headings : Animals; Antibodies, Bacterial / blood; Bacteremia / microbiology; Bacteremia / veterinary; Bartonella / genetics; Bartonella / immunology; Bartonella / isolation & purification; Bartonella Infections / immunology; Bartonella Infections / microbiology; Bartonella Infections / transmission; Bartonella Infections / veterinary; Cat Diseases / microbiology; Cats; DNA, Ribosomal / analysis; Dog Diseases / microbiology; Dogs; Fluorescent Antibody Technique; Humans; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; RNA, Ribosomal, 16S / genetics
TL;DR: Monitoring by blood culture and immunofluorescence assay (IFA) bartonella infection in one dog and eight cats in a household to determine the prevalence and persistence of the infection as well as its transmissibility to humans found it to be widespread and widespread. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1998 journal article

Sequential evaluation of dogs naturally infected with Ehrlichia canis, Ehrlichia chaffeensis, Ehrlichia equi, Ehrlichia ewingii, or Bartonella vinsonii

Journal of Clinical Microbiology, 36(9), 2645–2651.

By: E. Breitschwerdt, B. Hegarty & S. Hancock

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

A Retrospective Case-Control of Acute Renal Failure in 99 Dogs

Journal of Veterinary Internal Medicine, 11(2), 58–64.

By: S. Vaden n, J. Levine n & E. Breitschwerdt n

MeSH headings : Acute Kidney Injury / diagnosis; Acute Kidney Injury / epidemiology; Acute Kidney Injury / etiology; Acute Kidney Injury / veterinary; Animals; Case-Control Studies; Creatinine / blood; Demography; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / etiology; Dogs; Female; Logistic Models; Male; Retrospective Studies; Risk Factors; Seasons; Treatment Failure
TL;DR: Intact male dogs and nonsporting dogs were more likely to develop ARF and be admitted to the teaching hospital and dogs that survived in the hospital for more than 5 days were morelikely to recover and be discharged from the hospital. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1997 journal article

Bartonella clarridgeiae, a newly recognized zoonotic pathogen causing inoculation papules, fever, and lymphadenopathy (cat scratch disease)

Journal of Clinical Microbiology, 35(7), 1813–1818.

By: D. Kordick, E. Hilyard, T. Hadfield, K. Wilson, A. Steigerwalt, D. Brenner, E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Efficacy of enrofloxacin or doxycycline for treatment of Bartonella henselae or Bartonella clarridgeiae infection in cats.

Antimicrobial Agents and Chemotherapy, 41(11), 2448–2455.

By: D. Kordick n, M. Papich n & E. Breitschwerdt n

MeSH headings : Administration, Oral; Animals; Anti-Bacterial Agents / therapeutic use; Anti-Infective Agents / blood; Anti-Infective Agents / therapeutic use; Bartonella Infections / drug therapy; Bartonella Infections / veterinary; Bartonella henselae / drug effects; Cat Diseases / drug therapy; Cats; Chromatography, High Pressure Liquid; Doxycycline / blood; Doxycycline / therapeutic use; Drug Evaluation, Preclinical; Enrofloxacin; Fluoroquinolones; Microbial Sensitivity Tests; Quinolones / blood; Quinolones / therapeutic use
TL;DR: The results suggest that MICs obtained with axenic media do not predict antimicrobial activity against intracellular Bartonella, that a long treatment course is required to eliminate infection, and that duration of therapy correlates with pretreatment bacterial load. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1997 journal article

Epidemiologic evaluation of the risk factors associated with exposure and seroreactivity to Bartonella vinsonii in dogs

American Journal of Veterinary Research, 58(5), 467–471.

By: B. Pappalardo, M. Correa, C. York, C. Peat & E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

Immunoblot Analysis of the Immunoglobulin G Response to Ehrlichia Canis in Dogs: An International Survey

Journal of Veterinary Diagnostic Investigation, 9(1), 32–38.

By: B. Hegarty n, M. Levy n, R. Gager n & E. Breitschwerdt n

MeSH headings : Animals; Antibodies, Bacterial / blood; Antibody Formation; Antigens, Bacterial / immunology; Blotting, Western / methods; Dog Diseases; Dogs; Ehrlichia / genetics; Ehrlichia / immunology; Ehrlichiosis / immunology; Ehrlichiosis / veterinary; France; Genetic Variation; Immunoglobulin G / blood; Israel; Italy; United States; United States Virgin Islands; Zimbabwe
TL;DR: The results indicate that although relatively homogeneous, antigenic diversity may exist among E. canis organisms in different regions of the world, and that unique major proteins were observed in dog sera from Italy and Zimbabwe. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1997 journal article

Life-Threatening Cache Valley Virus Infection

New England Journal of Medicine, 336(8), 547–550.

By: D. Sexton*, P. Rollin*, E. Breitschwerdt n, G. Corey*, S. Myers*, M. Dumais*, M. Bowen*, C. Goldsmith* ...

MeSH headings : Adult; Bunyamwera virus / classification; Bunyamwera virus / isolation & purification; Bunyaviridae Infections / virology; Encephalitis, Viral / virology; Fatal Outcome; Humans; Male; Microscopy, Electron; Multiple Organ Failure / virology; North Carolina; Viremia / virology
TL;DR: The Bunyamwera serogroup of viruses contains more than 20 serologically cross-reactive viruses, 7 of which have been isolated in North America and are prevalent in livestock, large wild mammals, and humans from Alaska to Argentina. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: February 27, 2021

1997 journal article

Prednisolone at anti-inflammatory or immunosuppressive dosages in conjunction with doxycycline does not potentiate the severity of Rickettsia rickettsii infection in dogs.

Antimicrobial Agents and Chemotherapy, 41(1), 141–147.

By: E. Breitschwerdt n, M. Davidson n, B. Hegarty n, M. Papich n & C. Grindem n

MeSH headings : Animals; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / therapeutic use; Anti-Inflammatory Agents / blood; Anti-Inflammatory Agents / therapeutic use; Antibodies, Bacterial / analysis; Dogs; Doxycycline / blood; Doxycycline / therapeutic use; Drug Therapy, Combination; Female; Immunosuppressive Agents / blood; Immunosuppressive Agents / therapeutic use; Prednisolone / blood; Prednisolone / therapeutic use; Rickettsia rickettsii / immunology; Rickettsia rickettsii / isolation & purification; Rocky Mountain Spotted Fever / blood; Rocky Mountain Spotted Fever / drug therapy
TL;DR: It is concluded that the concurrent use of anti-inflammatory or immunosuppressive doses of prednisolone in conjunction with doxycycline, early in the course of experimental R MSF, confers no clinically relevant detrimental effects and that additional studies might be indicated to detect possible beneficial effects in cases of severe or potentially fulminant RMSF. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1997 journal article

Relapsing bacteremia after blood transmission of Bartonella henselae to cats

American Journal of Veterinary Research, 58(5), 492–497.

By: D. Kordick & E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

1997 journal article

THORACIC RADIOGRAPHIC FINDINGS IN DOGS INFECTED WITH RICKETTSIA RICKETTSII

Veterinary Radiology Ultrasound, 38(4), 260–266.

By: W. Drost n, C. Berry n, E. Breitschwerdt n & M. Davidson n

author keywords: dog; Rocky Mountain spotted fever; Rickettsia rickettsii; thoracic radiographs; ophthalmoscopy
MeSH headings : Animals; Dog Diseases / diagnostic imaging; Dog Diseases / drug therapy; Dogs; Female; Lung / diagnostic imaging; Male; Radiography, Thoracic / veterinary; Rocky Mountain Spotted Fever / diagnostic imaging; Rocky Mountain Spotted Fever / drug therapy; Rocky Mountain Spotted Fever / veterinary
TL;DR: Dogs with acute, experimentally-infected or naturally-occurring RMSF may have subtle pulmonary changes characterized by an unstructured interstitial pattern that is similar to that seen in animals infected with Rickettsia rickettsii. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1996 journal article

Bartonella vinsonii subsp. berkhoffii subsp. nov., Isolated from Dogs; Bartonella vinsonii subsp. vinsonii; and Emended Description of Bartonella vinsonii

International Journal of Systematic Bacteriology, 46(3), 704–709.

By: D. Kordick n, B. Swaminathan*, C. Greene*, K. Wilson*, A. Whitney*, S. O'Connor*, D. Hollis*, G. Matar* ...

MeSH headings : Animals; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonella / metabolism; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Base Sequence; DNA, Bacterial; Dog Diseases / microbiology; Dogs; Endocarditis, Bacterial / microbiology; Endocarditis, Bacterial / veterinary; Fatty Acids / analysis; Molecular Sequence Data; Polymerase Chain Reaction / veterinary; Polymorphism, Restriction Fragment Length; RNA, Bacterial; RNA, Ribosomal, 16S
TL;DR: Two bacterial strains were similar to Bartonella species, as determined by a number of phenotypic criteria, including growth characteristics, biochemical reactions, and cell wall fatty acid composition, and it is believed that strains 93-C01(T) and G7464 should be placed in a separate subspecies of B. vinsonii. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

1996 journal article

Comparative seroreactivity to Bartonella henselae and Bartonella quintana among cats from Israel and North Carolina

Veterinary Microbiology, 50(1-2), 95–103.

By: G. Baneth n, D. Kordick n, B. Hegarty n & E. Breitschwerdt n

author keywords: Bartonella henselae; Bartonella quintana; cat scratch disease
MeSH headings : Animals; Antibodies, Bacterial / blood; Bartonella henselae / immunology; Bartonella quintana / immunology; Cat-Scratch Disease / immunology; Cat-Scratch Disease / microbiology; Cats / immunology; Cats / microbiology; Cross Reactions; Fluorescent Antibody Technique, Indirect / veterinary; Humans; Israel; North Carolina; Species Specificity; Trench Fever / immunology; Trench Fever / microbiology
TL;DR: The data support the conclusion that B. henselae is the principal Bartonella species responsible for seroreactivity against B. quintana in naturally exposed cats from Israel or North Carolina and suggest that in Israel, cats are exposed to one or more antigenically different Bart onella species, sub-species or strains, that seroreact by IFA more intensely with B.Henselae. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

1996 journal article

Myocarditis in mice and guinea pigs experimentally infected with a canine-origin Borrelia isolate from Florida

American Journal of Veterinary Research, 57(4), 505–511.

By: E. Breitschwerdt, F. Geoly, D. Meuten, J. Levine, P. Howard, B. Hegarty, L. Stafford

Source: NC State University Libraries
Added: August 6, 2018

1996 journal article

PET imaging of pheochromocytoma (PHEO) in dogs using PARA [F-18]fluorobenzylguanidine (PFBG)

Journal of Nuclear Medicine, 37(5), 915.

By: P. Garg, C. Berry, R. DeGrado, F. Nutter, E. Breitschwerdt, M. Zalutsky, R. Coleman

Source: NC State University Libraries
Added: April 2, 2021

1995 journal article

Bartonellosis

Journal of the American Veterinary Medical Association, 206(12), 1928.

By: E. Breitschwerdt & D. Kordick

Source: NC State University Libraries
Added: August 6, 2018

1995 journal article

Diagnostic and therapeutic considerations in a hypercalcemic dog with multiple endocrine neoplasia

Journal of the American Animal Hospital Association, 31(2), 156–162.

By: K. Wright n, E. Breitschwerdt*, J. Feldman, C. Berry, D. Meuten & G. Spodnick

MeSH headings : 3-Iodobenzylguanidine; Adrenal Gland Neoplasms / diagnosis; Adrenal Gland Neoplasms / surgery; Adrenal Gland Neoplasms / veterinary; Animals; Calcium / blood; Contrast Media; Dog Diseases / diagnosis; Dog Diseases / surgery; Dogs; Female; Hypercalcemia / diagnosis; Hypercalcemia / surgery; Hypercalcemia / veterinary; Hyperparathyroidism / diagnosis; Hyperparathyroidism / veterinary; Iodine Radioisotopes; Iodobenzenes; Multiple Endocrine Neoplasia / diagnosis; Multiple Endocrine Neoplasia / surgery; Multiple Endocrine Neoplasia / veterinary; Parathyroid Hormone / blood; Parathyroid Neoplasms / diagnosis; Pheochromocytoma / diagnosis; Pheochromocytoma / surgery; Pheochromocytoma / veterinary; Technetium Tc 99m Sestamibi
TL;DR: Serum intact parathyroid hormone (iPTH), total serum calcium, and ionized serum calcium were increased prior to surgery, and subsequent high concentrations with increased serum iPTH concentrations confirmed concurrent primary hyperparathyroidism. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

1995 journal article

Endocarditis in a dog due to infection with a novel Bartonella subspecies

Journal of Clinical Microbiology, 33(1), 154.

By: E. Breitschwerdt, D. Kordick, D. Malarkey, B. Keene, T. Hadfield & K. Wilson

Source: NC State University Libraries
Added: August 6, 2018

1995 journal article

Erythrocyte fragility and chronic intermittent pigmenturia in a dog

Journal of American Veterinary Medical Association, 206(7), 1002–1006.

By: S. LeGrange, E. Breitschwerdt, C. Grindem & E. Beutler

Source: NC State University Libraries
Added: April 6, 2021

1995 journal article

Evaluation of the pathogenic potential of Rickettsia canada and Rickettsia prowazekii organisms in dogs

Journal of the American Veterinary Medical Association, 207(1), 58.

By: E. Breitschwerdt, B. Hegarty, M. Davidson & N. Szabados

Source: NC State University Libraries
Added: August 6, 2018

1995 journal article

Intraerythrocytic presence of bartonella henselae

Journal of Clinical Microbiology, 33(6), 1655–1656.

By: D. Kordick & E. Breitschwerdt

Source: NC State University Libraries
Added: April 6, 2021

1995 journal article

Prolonged bartonella bacteremia in cats associated with cat-scratch disease patients

Journal of Clinical Microbiology, 33(12), 3245–3251.

By: D. Kordick, K. Wilson, D. Sexton, T. Hadfield, H. Berkhoff & E. Breitschwerdt

Source: NC State University Libraries
Added: April 6, 2021

1995 journal article

The Effects of Cyclosporine Versus Standard Care in Dogs With Naturally Occurring Glomerulonephritis

Journal of Veterinary Internal Medicine, 9(4), 259–266.

By: S. Vaden n, E. Breitschwerdt n, P. Armstrong*, M. Correa n, C. Brown*, D. Polzin*, J. Brace*, S. DiBartola* ...

MeSH headings : Animals; Antigen-Antibody Complex / analysis; Cyclosporine / adverse effects; Cyclosporine / therapeutic use; Dog Diseases / drug therapy; Dog Diseases / mortality; Dogs; Drug Tolerance; Female; Gingival Hyperplasia / chemically induced; Glomerulonephritis / drug therapy; Glomerulonephritis / mortality; Glomerulonephritis / veterinary; Immunosuppressive Agents / adverse effects; Immunosuppressive Agents / therapeutic use; Male; Survival Rate; Treatment Outcome
TL;DR: The effects of cyclosporine (Cy) administration on the outcome of naturally occurring GN in dogs were determined and decreased appetite, diarrhea, vomiting, weight loss, involuntary shaking, and thrombocytopenia were noted in both treatment groups; however, clinical signs in Cy-treated dogs subjectively were more severe. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 20, 2019

1994 journal article

Canine mitochondrial myopathy associated with reduced mitochondrial mRNA and altered cytochrome c oxidase activities in fibroblasts and skeletal muscle

Comparative Biochemistry and Physiology Part A: Physiology, 109(4), 887–894.

By: C. Vijayasarathy*, U. Giger*, U. Prociuk*, D. Patterson*, E. Breitschwerdt n & N. Avadhani*

author keywords: MITOCHONDRIAL MYOPATHY; CYTOCHROME C OXIDASE; ATPASE; MITOCHONDRIAL RNA; MITOCHONDRIAL ENZYMES
MeSH headings : Adenosine Triphosphatases / genetics; Adenosine Triphosphatases / metabolism; Animals; Dogs; Electron Transport Complex IV / metabolism; Fibroblasts / metabolism; Genome; Mitochondria / metabolism; Mitochondrial Myopathies / genetics; Muscle, Skeletal / metabolism; RNA / metabolism; RNA, Messenger / metabolism; RNA, Mitochondrial
TL;DR: Results suggest that a mitochondrial dysfunction may be the causative factor of the exertional metabolic myopathy with lactic acidosis in this affected old English sheep dog. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: February 27, 2021

1994 journal article

Fanconi's Syndrome in a Dog With Primary Hypoparathyroidism

Journal of Veterinary Internal Medicine, 8(5), 349–354.

By: L. Freeman n, E. Breitschwerdt n, B. Keene n & B. Hansen n

MeSH headings : Animals; Blood Chemical Analysis / veterinary; Calcitriol / blood; Calcitriol / deficiency; Calcitriol / therapeutic use; Calcium / therapeutic use; Dihydrotachysterol / therapeutic use; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / etiology; Dogs; Fanconi Syndrome / blood; Fanconi Syndrome / diagnosis; Fanconi Syndrome / etiology; Fanconi Syndrome / veterinary; Hypoparathyroidism / blood; Hypoparathyroidism / complications; Hypoparathyroidism / diagnosis; Hypoparathyroidism / veterinary; Male; Parathyroid Hormone / blood; Parathyroid Hormone / deficiency; Water-Electrolyte Imbalance / veterinary
TL;DR: An 11-year-old castrated male mixed breed dog was referred for evaluation of muscle twitching, polyuria, polydipsia, anorexia, and periocular alopecia, and Fanconi's syndrome, which was supported by the presence of hypokalemia and increased urinary fractional excretion of sodium, potassium, calcium, phosphorus, and magnesium. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

1994 journal article

Natural infections with Borrelia spirochetes in two dogs from Florida

Journal of Clinical Microbiology, 32(2), 352–357.

By: E. Breitschwerdt, W. Nicholson, A. Kiehl, C. Steers, D. Meuten & J. Levine

Source: NC State University Libraries
Added: August 6, 2018

1994 journal article

The Use of a Polymerase Chain Reaction as a Diagnostic Test for Rocky Mountain Spotted Fever

The American Journal of Tropical Medicine and Hygiene, 50(1), 59–63.

By: D. Sexton, S. Kanj, K. Wilson, G. Corey, B. Hegarty, M. Levy, E. Breitschwerdt*

TL;DR: Findings confirm earlier findings that the PCR can detect R. rickettsii, but the need for reamplification indicates that the lack of sensitivity is a serious limitation in the usefulness of the PCR as a clinical diagnostic test. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: February 27, 2021

1994 journal article

Thrombocytopenia Associated With Neoplasia in Dogs

Journal of Veterinary Internal Medicine, 8(6), 400–405.

By: C. Grindem n, E. Breitschwerdt n, W. Corbett n, R. Page n & H. Jans n

MeSH headings : Animals; Dog Diseases / etiology; Dogs; Female; Male; Neoplasms / complications; Neoplasms / veterinary; Prevalence; Risk Factors; Thrombocytopenia / etiology; Thrombocytopenia / veterinary
TL;DR: If thrombocytopenia is identified in a dog with cancer, it is recommended thorough evaluation of the coagulation system before surgery or therapy, and careful consideration of the risks and potential benefits of myelosuppressive or L-asparaginase therapy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

1993 journal article

Acute membranous glomerulopathy in a dog with retrobulbar cellulitis

Journal of the American Animal Hospital Association, 29(6), 536.

By: E. Breitschwerdt, M. Menard, J. Cullen & M. Davidson

Source: NC State University Libraries
Added: August 6, 2018

1993 journal article

Brazilian Spotted Fever in Espirito Santo, Brazil: Description of a Focus of Infection in a New Endemic Region

The American Journal of Tropical Medicine and Hygiene, 49(2), 222–226.

By: D. Sexton*, M. Muniz*, G. Corey*, E. Breitschwerdt*, B. Hegarty*, S. Dumler*, D. Walker*, P. Pecanha*, R. Dietze*

MeSH headings : Adult; Animals; Antibodies, Bacterial / blood; Brazil / epidemiology; Disease Outbreaks; Dog Diseases / epidemiology; Dogs; Female; Fluorescent Antibody Technique; Humans; Male; Middle Aged; Rickettsia Infections / epidemiology; Rickettsia Infections / veterinary; Rickettsia rickettsii / immunology; Skin / pathology
TL;DR: Two proven and four suspected cases of Brazilian spotted fever and the results of the canine serosurvey suggest that a focus of virulent disease exists in an area not previously known to be endemic for SFG rickettsiae. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: February 27, 2021

1993 journal article

Comparison of latex agglutination, indirect immunofluorescent antibody, and enzyme immunoassay methods for serodiagnosis of rocky mountain spotted fever in dogs

American Journal of Veterinary Research, 54(1), 20–28.

By: C. Greene, M. Marks, M. Lappin, E. Breitschwerdt, N. Wolski & W. Burgdorfer

Source: NC State University Libraries
Added: April 6, 2021

1993 journal article

Endemic Visceral Leishmaniasis in a Dog from Texas

Journal of Veterinary Internal Medicine, 7(1), 16–19.

By: R. Sellon*, M. Menard*, D. Meuten*, E. Lengerich n, F. Steurer n & E. Breitschwerdt*

MeSH headings : Animals; Antibodies, Protozoan / analysis; Dog Diseases / diagnosis; Dogs; Female; Fluorescent Antibody Technique / veterinary; Leishmania donovani / immunology; Leishmaniasis, Visceral / diagnosis; Leishmaniasis, Visceral / veterinary; Male
TL;DR: Evidence of response to treatment with diminazene aceturate and ketoconazole included improvement in the abnormal clinical, hematologic, and biochemical findings, decreased serum globulin concentration and antibody titer to Leishmania donovani, and absence of organisms in examined tissues. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

1993 journal article

Risk factors associated with acute pancreatitis in dogs: 101 cases (1985-1990)

Journal of the American Veterinary Medical Association, 203(5), 673–679.

By: A. Cook, E. Breitschwerdt, J. Levine, S. Bunch & L. Linn

Source: NC State University Libraries
Added: August 6, 2018

1993 journal article

Thrombocytopenia in Cats: A Retrospective Study of 41 Cases

Journal of Veterinary Internal Medicine, 7(5), 261–265.

By: H. Jordan n, C. Grindem n & E. Breitschwerdt n

MeSH headings : Animals; Cat Diseases / etiology; Cats; Female; Heart Diseases / complications; Heart Diseases / veterinary; Infections / complications; Infections / veterinary; Male; Neoplasms / complications; Neoplasms / veterinary; Prevalence; Retrospective Studies; Thrombocytopenia / etiology; Thrombocytopenia / veterinary
TL;DR: No significant differences were found between groups with respect to platelet count, packed cell volume, or white blood cell count, though anemia and leukopenia were common among the cats as a whole, and Bleeding disorders were observed in 29% of thrombocytopenic cats and were more likely to be associated with neoplasia, cardiac disease, and platelet counts less than or equal to 30,000/microL. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

1993 journal article

Tickborne diseases of dogs

Veterinary Technician, 14(5), 291.

By: E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

1993 journal article

Use of 123 Iodine Metaiodobenzylguanidine Scintigraphy for the Diagnosis of a Pheochromocytoma in a dog

Veterinary Radiology and Ultrasound, 34(1), 52–55.

By: C. Berry n, K. Wright n, E. Breitschwerdt n & J. Feldman*

author keywords: CANINE PHEOCHROMOCYTOMA; I-123-METAIODOBENZYLGUANIDINE SCINTIGRAPHY
TL;DR: A 13-year-old neutered female Yorkshire terrier presented with a history of progressive episodic weakness and disorientation of 4 months duration and a pheochromocytoma was confirmed histologically after surgical excision. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: February 27, 2021

1993 journal article

Whats new in tick transmitted disease

Proceedings of the Annual Veterinary Medical Forum, 446.

By: E. Breitschwerdt

Source: NC State University Libraries
Added: April 6, 2021

1992 journal article

Effects of dietary protein source on Basenjis with immunoproliferative enteropathy

American Journal of Veterinary Research, 53(2), 234.

By: E. Breitschwerdt, D. Hirakawa, S. Hurlbert, T. Gerig & C. Babineau

Source: NC State University Libraries
Added: August 6, 2018

1992 journal article

Episodic weakness associated with exertional lactic acidosis and myopathy in old English Sheepdog littermates

Journal of the American Veterinary Medical Association, 201(5), 731.

By: E. Breitschwerdt, J. Kornegay, S. Wheeler, J. Stevens & C. Baty

Source: NC State University Libraries
Added: August 6, 2018

1992 journal article

Immunoproliferative enteropathy of Basenjis

Seminars in Veterinary Medicine and Surgery (Small Animal), 7(2), 153.

By: E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

1992 journal article

Seroprevalence of babesiosis in greyhounds in Florida

Journal of American Veterinary Medical Association, 200(1), 47–50.

By: J. Taboada, J. Harvey, M. Levy & E. Breitschwerdt

Source: NC State University Libraries
Added: May 18, 2021

1991 journal article

Acute blindness associated with intracranial tumors in dogs and cats: Eight cases (1984-1989)

Journal of American Veterinary Medical Association, 199(6), 755–758.

By: M. Davidson, M. Nasisse, E. Breitschwerdt, D. Thrall, R. Page, V. Jamieson, R. English

Source: NC State University Libraries
Added: May 18, 2021

1991 journal article

Bone marrow hypoplasia in a cat treated with griseofulvin

Journal of American Veterinary Medical Association, 198(3), 429–431.

By: J. Rottman, R. English, E. Breitschwerdt & D. Duncan

Source: NC State University Libraries
Added: May 18, 2021

1991 journal article

Efficacy of chloramphenicol, enrofloxacin, and tetracycline for treatment of experimental Rocky Mountain spotted fever in dogs.

Antimicrobial Agents and Chemotherapy, 35(11), 2375–2381.

By: E. Breitschwerdt n, M. Davidson n, D. Aucoin n, M. Levy n, N. Szabados n, B. Hegarty n, A. Kuehne n, R. James n

MeSH headings : Animals; Anti-Infective Agents / therapeutic use; Antibodies, Bacterial / analysis; Capillary Permeability / physiology; Chloramphenicol / therapeutic use; Dogs; Enrofloxacin; Female; Fluorescent Antibody Technique; Fluoroquinolones; Quinolones / therapeutic use; Rocky Mountain Spotted Fever / drug therapy; Rocky Mountain Spotted Fever / microbiology; Rocky Mountain Spotted Fever / physiopathology; Tetracycline / therapeutic use; Vero Cells
TL;DR: It is concluded that chloramphenicol, enrofloxacin, and tetracycline are equally efficacious for treating experimental canine RMSF. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1991 journal article

Epidemiologic Survey of Thrombocytopenia in Dogs: A Report on 987 Cases

Veterinary Clinical Pathology, 20(2), 38–43.

By: C. Grindem n, E. Breitschwerdt n, W. Corbett n & H. Jans n

TL;DR: It is concluded that thrombocytopenia is a prevalent and potentially important diagnostic finding in a variety of disease states. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018

1991 journal article

Gastric Acid Secretion in Basenji Dogs With Immunoproliferative Enteropathy

Journal of Veterinary Internal Medicine, 5(1), 34–39.

By: E. Breitschwerdt n, N. MacLachlan, R. Argenzio n, S. Hurlbert, C. Babineau & E. Buysscher

MeSH headings : Acepromazine; Anesthesia / veterinary; Animals; Breeding; Diarrhea / metabolism; Diarrhea / veterinary; Dog Diseases / metabolism; Dogs; Enteritis / metabolism; Enteritis / veterinary; Female; Gastric Acid / metabolism; Gastrins / blood; Gastritis / metabolism; Gastritis / veterinary; Immunoproliferative Small Intestinal Disease / metabolism; Immunoproliferative Small Intestinal Disease / veterinary; Male; Oxymorphone; Pentobarbital
TL;DR: The combination of oxymorphone and acepromazine provides an acceptable means of restraint in dogs undergoing acid secretory studies, and results of the secretin stimulation studies support previous pathologic studies that failed to detect gastrin-secreting tumors. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

1991 journal article

Intrahepatic Postsinusoidal Venous Obstruction in a Dog

Journal of Veterinary Internal Medicine, 5(6), 317–321.

By: L. Cohn*, K. Spaulding n, J. Cullen n, S. Bunch, M. Metcalf, E. Hardie, N. MacLachlan n, E. Breitschwerdt*

MeSH headings : Animals; Blood Pressure; Budd-Chiari Syndrome / diagnosis; Budd-Chiari Syndrome / diagnostic imaging; Budd-Chiari Syndrome / veterinary; Dog Diseases / diagnosis; Dog Diseases / diagnostic imaging; Dogs; Female; Hepatic Veins / diagnostic imaging; Hepatic Veins / pathology; Hepatic Veins / physiopathology; Liver / diagnostic imaging; Liver / pathology; Manometry / veterinary; Radiography; Ultrasonography
TL;DR: Intrahepatic postsinusoidal obstruction, similar to congenital Budd-Chiari syndrome in human patients, was diagnosed in a young Basenji dog. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, Web Of Science
Added: August 6, 2018

1991 journal article

Postsurgical mortality secondary to zinc toxicity in dogs

Veterinary and Human Toxicology, 33(6), 579–583.

By: K. Meurs, E. Breitschwerdt, C. Baty & M. Young

Source: NC State University Libraries
Added: May 18, 2021

1991 journal article

Primary ciliary dyskinesia in Bichon frise littermates

Journal of the American Animal Hospital Association, 27, 633–640.

By: S. Vaden, E. Breitschwerdt, C. Henrickson, M. Metcalf, L. Cohn & W. Craig

Source: NC State University Libraries
Added: September 6, 2019

1990 journal article

Acute-renal-failure after methylene-blue infusion in a dog

Journal of the American Animal Hospital Association, 26(4), 410–412.

By: D. Osuna, P. Armstrong, D. Duncan & E. Breitschwerdt

Source: NC State University Libraries
Added: May 18, 2021

1990 journal article

An epizootic of peroneal and tibial neuropathy in walker hound pups

Journal of American Veterinary Medical Association, 197(4), 498–500.

By: H. Jans, J. Kornegay, E. Breitschwerdt & P. Armstrong

Source: NC State University Libraries
Added: May 18, 2021

1990 journal article

Kinetics of IgM and IgG responses to experimental and naturally required Rickettsia rickettsii infection in dogs

American Journal of Veterinary Research, 51(8), 1312.

By: E. Breitschwerdt, M. Levy, M. Davidson, D. Walker, W. Burgdorfer, B. Curtis, C. Babineau

Source: NC State University Libraries
Added: August 6, 2018

1990 journal article

Platelet Aggregation in Dogs Experimentally Infected with Rickettsia rickettsii

Veterinary Clinical Pathology, 19(1), 25–28.

By: C. Grindem*, W. Corbett*, M. Levy*, M. Davidson n & E. Breitschwerdt n

TL;DR: Platelet aggregation studies were performed on nine Beagle dogs experimentally infected with Rickettsia rickettsia, and Platelets from dogs with Rocky Mountain spotted fever tended to be more aggregable than controls. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 1, 2020

1990 journal article

Tick-borne zoonoses

Veterinary Technician, 11(4), 249.

By: E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

1990 journal article

Vascular permeability and coagulation during rickettsia rickettsii infection in dogs

American Journal of Veterinary Research, 51(1), 165–170.

By: M. Davidson, E. Breitschwerdt, D. Walker, M. Levy, C. Carlson, E. Hardie, C. Grindem, M. Nasisse

Source: NC State University Libraries
Added: May 18, 2021

1989 journal article

Identification of Rickettsiae in Cutaneous i Biopsy Specimens From Dogs With Experimental Rocky Mountain Spotted Fever

Journal of Veterinary Internal Medicine, 3(1), 7–11.

By: M. Davidson n, E. Breitschwerdt*, D. Walker n, M. Nasisse & W. Sussman

TL;DR: Direct immunofluorescence reaction for Rickettsia rickettsii was performed on formalin-fixed, paraffin-embedded cutaneous biopsy specimens collected from dogs with experimental Rocky Mountain spotted fever, suggesting that clinical application of this technique for diagnosis of RMSF may be limited in dogs without cutaneous lesions. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 27, 2021

1989 journal article

Ocular manifestations of rocky mountain spotted fever in dogs

Journal of American Veterinary Medical Association, 194(6), 777–781.

By: M. Davidson, E. Breitschwerdt, M. Nasisse & S. Roberts

Source: NC State University Libraries
Added: May 18, 2021

1989 journal article

Taking a second hard look at borrelia burgdorferi

Journal of American Veterinary Medical Association, 195(5), 562–563.

By: R. Green, W. Nicholson, E. Breitschwerdt & J. Levine

Source: NC State University Libraries
Added: May 18, 2021

1988 journal article

Antibodies toEhrlichia canis, Ehrlichia platys, and Spotted Fever Group Rickettsiae in Louisiana Dogs

Journal of Veterinary Internal Medicine, 2(2), 55–59.

By: J. Hoskins*, E. Breitschwerdt n, S. Gaunt*, T. French* & W. Burgdorfer*

MeSH headings : Animals; Antibodies, Bacterial / analysis; Dog Diseases / epidemiology; Dog Diseases / immunology; Dogs; Ehrlichia / immunology; Louisiana; Rickettsia Infections / epidemiology; Rickettsia Infections / immunology; Rickettsia Infections / veterinary; Rickettsia rickettsii / immunology; Rickettsiaceae / immunology; Rickettsiaceae Infections / epidemiology; Rickettsiaceae Infections / immunology; Rickettsiaceae Infections / veterinary; Thrombocytopenia / immunology; Thrombocytopenia / veterinary
TL;DR: Simultaneous examination of increased serum antibody titers (greater than or equal to 1:64) to four SFG rickettsiae indicate thatRickettsia rhipicephali and Rickettsia montana accounted for the majority of the antibodies detected in these dogs. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: January 24, 2021

1988 journal article

Antibody to Borrelia burgdorferi in dogs in North Carolina

American Journal of Veterinary Research, 49, 473–476.

By: R. Greene, J. Levine, E. Breitschwerdt & H. Berkhoff

Source: NC State University Libraries
Added: August 6, 2018

1988 journal article

Clinical and serologic evaluations of induced Borrelia burgdorferi infections in dogs

American Journal of Veterinary Research, 49, 752–757.

By: R. Greene, J. Levine, E. Breitschwerdt, R. Walker, H. Berkhoff & W. Nicholson

Source: NC State University Libraries
Added: August 6, 2018

1988 journal article

Clinical, hematologic, and humoral immune response in female dogs inoculated with rickettsia rickettsii and rickettsia montana

American Journal of Veterinary Research, 49(1), 70–76.

By: E. Breitschwerdt, D. Walker, M. Levy, W. Burgdorfer, W. Corbett, S. Hurlbert, M. Stebbins, B. Curtis, D. Allen

Source: NC State University Libraries
Added: May 18, 2021

1988 journal article

Elevated serum IgA associated with immunoproliferative enteropathy of Basenji dogs: Lack of evidence for alpha heavy-chain disease or enhanced intestinal IgA secretion

Veterinary Immunology and Immunopathology, 20(1), 41–52.

By: E. De Buysscher n, E. Breitschwerdt n & N. MacLachlan n

MeSH headings : Animals; Dog Diseases / genetics; Dog Diseases / immunology; Dogs; Female; Immunoglobulin A / analysis; Immunoglobulin A / metabolism; Immunoglobulin alpha-Chains / analysis; Immunoproliferative Small Intestinal Disease / immunology; Immunoproliferative Small Intestinal Disease / veterinary; Jejunum / immunology; Jejunum / metabolism; Male
TL;DR: The results of this study indicate that immunoproliferative enteropathy of Basenjis resembles closely the nonsecretory form of human immunoproleiferative small intestinal disease (IPSID). (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: September 1, 2020

1988 journal article

Gastroenteritis of Basenji Dogs

Veterinary Pathology, 25(1), 36–41.

By: N. MacLachlan n, E. Breitschwerdt n, J. Chambers n, R. Argenzio n & E. De Buysscher n

MeSH headings : Animals; Diarrhea / genetics; Diarrhea / pathology; Diarrhea / veterinary; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Female; Fluorescent Antibody Technique; Gastroenteritis / genetics; Gastroenteritis / pathology; Gastroenteritis / veterinary; Immunoglobulins / analysis; Intestinal Mucosa / pathology; Intestines / pathology; Jejunum / immunology; Jejunum / pathology; Male; Pedigree; Stomach / pathology
TL;DR: Inter intestinal function was abnormal in both affected and asymptomatic Basenji dogs evaluated by combined N-benozoyl-L-tyrosyl-p-aminobenzoic acid and d-xylose test, but malabsorption and maldigestion were most pronounced in affected Basenjee dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: September 1, 2020

1988 journal article

Immunoblot analysis of immunoglobulin G response to the lyme disease agent (borrelia burgdorferi) in experimentally and naturally exposed dogs

Journal of Clinical Microbiology, 26(4), 648–653.

By: R. Greene, R. Walker, W. Nicholson, H. Heidner, J. Levine, E. Burgess, M. Wyand, E. Breitschwerdt, H. Berkhoff

Source: NC State University Libraries
Added: May 18, 2021

1988 journal article

Infectious thrombocytopenia in dogs

Compendium on Continuing Education for the Practicing Veterinarian, 10(10), 1177–1191.

By: E. Breitschwerdt

Source: NC State University Libraries
Added: May 18, 2021

1988 journal article

Zollinger-ellison syndrome and myelofibrosis in a dog

Journal of American Veterinary Medical Association, 192(10), 1430–1434.

By: R. English, E. Breitschwerdt, C. Grindem, D. Thrall & L. Gainsburg

Source: NC State University Libraries
Added: May 18, 2021

1987 journal article

Antibodies to spotted fever-group rickettsiae in dogs in North Carolina

American Journal of Veterinary Research, 48(10), 1436–1440.

By: E. Breitschwerdt, D. Moncol, W. Corbett, J. MacCormack, W. Burgdorfer, R. Ford, M. Levy

Source: NC State University Libraries
Added: May 18, 2021

1987 journal article

Antibody activity to babesia canis in dogs in North Carolina

American Journal of Veterinary Research, 48(3), 339–341.

By: M. Levy, E. Breitschwerdt & D. Moncol

Source: NC State University Libraries
Added: May 18, 2021

1987 journal article

Monoclonal Gammopathy Associated With Naturally Occurring Canine Ehrlichiosis

Journal of Veterinary Internal Medicine, 1(1), 2–9.

By: E. Breitschwerdt n, B. Woody*, C. Zerbe*, E. Buysscher n & O. Barta*

MeSH headings : Anemia / pathology; Animals; Blood Cell Count; Blood Proteins / analysis; Diagnosis, Differential; Dog Diseases / immunology; Dog Diseases / pathology; Dogs; Ehrlichia / isolation & purification; Female; Male; Paraproteinemias / immunology; Paraproteinemias / pathology; Paraproteinemias / veterinary; Proteinuria / urine; Retrospective Studies; Rickettsiaceae Infections / immunology; Rickettsiaceae Infections / pathology; Rickettsiaceae Infections / veterinary
TL;DR: It is concluded that an E. canis antibody titer should be determined in all dogs in which a diagnosis of benign monoclonal gammopathy is contemplated or definitive evidence of myeloma, leukemia, or macroglobulinemia is lacking. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 1, 2020

1987 journal article

Rhinitis, pneumonia, and defective neutrophil function in the doberman pinscher

American Journal of Veterinary Research, 48(7), 1054–1062.

By: E. Breitschwerdt, T. Brown, E. De Buysscher, B. Andersen, D. Thrall, E. Hager, G. Ananaba, M. Degen, M. Ward

Source: NC State University Libraries
Added: May 18, 2021

1986 journal article

3 cases of acute zinc toxicosis in dogs

Veterinary and Human Toxicology, 28(2), 109–117.

By: E. Breitschwerdt, P. Armstrong, C. Robinette, R. Dillman, M. Karl & E. Lowry

Source: NC State University Libraries
Added: May 18, 2021

1986 journal article

Chronic azotemia and hypertension in 2 bluetick coonhound siblings

Compendium on Continuing Education for the Practicing Veterinarian, 8(7), 487–491.

By: E. Breitschwerdt, M. Turk, M. Glaze, M. Crawford, M. Littlefield & A. Roussel

Source: NC State University Libraries
Added: May 18, 2021

1986 journal article

Cultivation of Rhinosporidium seeberi in vitro: interaction with epithelial cells

Science, 234(4775), 474–476.

By: M. Levy n, D. Meuten n & E. Breitschwerdt n

MeSH headings : Animals; Cell Cycle; Cells, Cultured; Dogs; Epithelium / microbiology; Humans; Polyps / microbiology; Rhinosporidium / growth & development
TL;DR: Rhinosporidium seeberi, a fungus that is associated with polyp-like tumors in animals and man, was successfully cultivated and stimulated proliferation of epithelial cells in vitro, producing polyp -like structures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: September 1, 2020

1986 journal article

Nasal Rhinosporidiosis in the Dog

Veterinary Pathology, 23(1), 50–56.

By: J. Easley n, D. Meuten n, M. Levy n, M. Dykstra n, E. Breitschwerdt n, E. Holzinger n, R. Cattley n

MeSH headings : Animals; Dog Diseases / pathology; Dogs; Female; Male; Nasal Polyps / pathology; Nasal Polyps / veterinary; Neutrophils / cytology; Nose Diseases / pathology; Nose Diseases / veterinary; Rhinosporidiosis / pathology; Rhinosporidiosis / veterinary; Staining and Labeling
TL;DR: The organism from one dog was cultured and grown in vitro for 7 months and is the first successful cultivation of Rhinosporidium seeberi. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 27, 2021

1986 journal article

Rhinosporidiosis in 2 dogs

Zentralblatt Fur Bakteriologie Mikrobiologie Und Hygiene, 262(1), 103–104.

By: M. Dykstra, J. Easley, D. Meuten, M. Levy, E. Breitschwerdt & E. Holzinger

Source: NC State University Libraries
Added: May 18, 2021

1985 journal article

Canine rocky mountain spotted fever: A kennel epizootic

American Journal of Veterinary Research, 46(10), 2124–2128.

By: E. Breitschwerdt, D. Meuten, D. Walker, M. Levy, K. Kennedy, M. King, B. Curtis

Source: NC State University Libraries
Added: May 18, 2021

1985 journal article

Idiopathic hyperaldosteronism in a dog

Journal of the American Veterinary Medical Association, 187(8), 841–845.

By: E. Breitschwerdt, D. Meuten, C. Greenfield, L. Anson, C. Cook & R. Fulghum

Source: NC State University Libraries
Added: May 18, 2021

1985 journal article

Mycotic keratitis in a dog: Concurrent aspergillus sp and curvularia sp infections

Journal of the American Veterinary Medical Association, 186(9), 975–976.

By: C. Qualls, F. Chandler, W. Kaplan, E. Breitschwerdt & D. Cho

Source: NC State University Libraries
Added: May 18, 2021

1984 journal article

Clinical and laboratory characterization of basenjis with immunoproliferative small intestinal disease

American Journal of Veterinary Research, 45(2), 267–273.

By: E. Breitschwerdt, R. Ochoa, M. Barta, O. Barta, J. McClure & C. Waltman

Source: NC State University Libraries
Added: May 18, 2021

1984 journal article

Immunoproliferative small intestinal disease in basenji dogs: Morphologic observations

American Journal of Veterinary Research, 45(3), 482–490.

By: R. Ochoa, E. Breitschwerdt & K. Lincoln

Source: NC State University Libraries
Added: May 18, 2021

1984 journal article

Serologic pattern of canine heartworm (dirofilaria immitis) infection

American Journal of Veterinary Research, 45(6), 1178–1183.

By: L. Glickman, R. Grieve, E. Breitschwerdt, M. Mika-Grieve, G. Patronek, L. Domanski, C. Root, J. Malone

Source: NC State University Libraries
Added: May 18, 2021

1983 journal article

Babesiosis in the greyhound

Journal of the American Veterinary Medical Association, 182(9), 978–982.

By: E. Breitschwerdt, J. Malone, P. MacWilliams, M. Levy, C. Qualls & M. Prudich

Source: NC State University Libraries
Added: May 18, 2021

1983 journal article

Lymphocyte transformation and humoral immune factors in basenji dogs with immunoproliferative small intestinal disease

American Journal of Veterinary Research, 44(10), 1954–1959.

By: O. Barta, E. Breitschwerdt, L. Shaffer & S. Pourciau

Source: NC State University Libraries
Added: May 18, 2021

1983 journal article

Multiple endocrine abnormalities in basenji dogs with renal tubular dysfunction

Journal of the American Veterinary Medical Association, 182(12), 1348–1353.

By: E. Breitschwerdt, R. Ochoa & C. Waltman

Source: NC State University Libraries
Added: May 18, 2021

1983 journal article

PULMONARY ACTINOMYCOSIS IN A DOG

Veterinary Radiology, 24(4), 186–188.

By: E. Breitschwerdt n & J. Watters n

TL;DR: A six-year-old spayed female mixed-breed dog was evaluated for coughing, dyspnea, exercise intolerance, and intermittent fever of four month's duration; however, radiographic evidence of a severe pulmonary pathologic condition remained 45 days after the initiation of therapy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 2, 2020

1983 journal article

Serum proteins in healthy basenjis and basenjis with chronic diarrhea

American Journal of Veterinary Research, 44(2), 326–328.

By: E. Breitschwerdt, O. Barta, C. Waltman, N. Hubbert, S. Pourciau & W. Liu

Source: NC State University Libraries
Added: May 18, 2021

1982 journal article

Clinical and epidemiologic characterization of a diarrheal syndrome in basenji dogs

Journal of the American Veterinary Medical Association, 180(8), 914–920.

By: E. Breitschwerdt, C. Waltman, H. Hagstad, R. Ochoa, J. McClure & O. Barta

Source: NC State University Libraries
Added: May 18, 2021

1981 journal article

Hypoglycemia in four dogs with sepsis

Journal of the American Veterinary Medical Association, 178(10), 1072–1076.

By: E. Breitschwerdt, A. Loar, T. Hribernik & R. McGrath

Source: NC State University Libraries
Added: May 18, 2021

1981 journal article

Nephrogenic diabetes insipidus in three dogs

Journal of the American Veterinary Medical Association, 179(3), 235–238.

By: E. Breitschwerdt, J. Verlander & T. Hribernik

Source: NC State University Libraries
Added: May 18, 2021

1980 journal article

Strongyloides stercoralis-like infection in a dog

Journal of the American Veterinary Medical Association, 176(2), 130–133.

By: J. Malone, E. Breitschwerdt, M. Little, R. Ochoa & K. Wolf

Source: NC State University Libraries
Added: May 18, 2021

1980 journal article

Tubular hypoplasia of the ascending aorta and patent ductus arteriosus in a dog

Journal of the American Veterinary Medical Association, 176(6), 536–538.

By: G. Sandusky, E. Breitschwerdt & D. Duplantier

Source: NC State University Libraries
Added: May 18, 2021

1979 journal article

Inappropriate secretion of antidiuretic hormone in a dog

Journal of the American Veterinary Medical Association, 175(2), 181–186.

By: E. Breitschwerdt & C. Root

Source: NC State University Libraries
Added: May 18, 2021

personal communication

Bartonella henselae and B-koehlerae DNA in Birds

Mascarelli, P. E., McQuillan, M., Harms, C. A., Harms, R. V., & Breitschwerdt, E. B.

By: P. Mascarelli, M. McQuillan, C. Harms, R. Harms & E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

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