Works (539)

Updated: September 22nd, 2024 06:15

2024 journal article

<i>Bartonella</i> species bacteremia in association with adult psychosis

FRONTIERS IN PSYCHIATRY, 15.

By: S. Delaney*, C. Robveille n, R. Maggi n, E. Lashnits*, E. Kingston n, C. Liedig n, L. Murray*, B. Fallon*, E. Breitschwerdt n

author keywords: Bartonella; infection; psychosis; serology; polymerase chain reaction; neurologic diseases
Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 1, 2024

2024 journal article

<i>Bartonella</i> spp. infection in people with Mild Cognitive Impairment: A pilot study

PLOS ONE, 19(8).

By: V. Guirguis*, F. Pupillo*, S. Rodrigues*, N. Walker*, H. Roth*, C. Liedig n, R. Maggi n, E. Breitschwerdt*, F. Frohlich*

UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 16, 2024

2024 journal article

A case of mistaken identity: a systematic review, meta-analysis, and reinvestigation of hemotropic <i>Mycoplasma</i> spp. infection in <i>Ctenocephalides felis</i> (cat flea)

PARASITES & VECTORS, 17(1).

By: C. Moore n, E. Lashnits*, M. Lappin*, J. Hawley* & E. Breitschwerdt n

author keywords: Ctenocephalides felis; Cat flea; Hemotropic mycoplasma; Vector-borne; Flea-borne pathogen; Mycoplasma haemofelis; Candidatus Mycoplasma turicensis; Mycoplasma haemominutum
Sources: Web Of Science, NC State University Libraries
Added: May 20, 2024

2024 journal article

A comparison of <i>Bartonella henselae</i> infection in immunocompetent and immunocompromised mice

PLOS ONE, 19(2).

By: R. Bullard*, M. Cheslock*, S. Gadila*, R. Maggi n, E. Breitschwerdt n, A. Saied*, M. Embers*

TL;DR: Data indicate that SCID/Beige mice can provide a model to study Bartonella infection, therapeutics, and vector dynamics in the future. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: March 11, 2024

2024 article

Antibodies to <i>Borrelia burgdorferi</i> and <i>Bartonella</i> species in serum and synovial fluid from people with rheumatic diseases

Kim, L., Lashnits, E., Breitschwerdt, E. B., Elam, A., Grade, N., Miller, J., & Shikhman, A. R. (2024, March 14). MICROBIOLOGY SPECTRUM, Vol. 3.

By: L. Kim*, E. Lashnits*, E. Breitschwerdt n, A. Elam*, N. Grade*, J. Miller*, A. Shikhman

author keywords: antibodies; Bartonella; Borrelia burgdorferi; immunoserology; Lyme; serodiagnosis; rheumatology
Sources: Web Of Science, NC State University Libraries
Added: April 8, 2024

2024 journal article

Assessment of the effect of long-term serum storage for retrospective serologic diagnosis of canine monocytic ehrlichiosis (<i> Ehrlichia</i> canis )

COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES, 108.

By: M. Karagkouni*, K. Spilioti, E. Meletis*, P. Kostoulas*, C. Koutinas*, K. Theodorou, E. Breitschwerdt n, M. Mylonakis*

author keywords: Diagnosis; Dog; Ehrlichia canis; Serology; Storage time
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 28, 2024

2024 article

Diagnostic challenge in veterinary pathology: Tri-cavitary effusion in a cat with systemic pyogranulomatous inflammation

Fingerhood, S., Neupane, P., Breitschwerdt, E. B., & Choi, E. A. (2024, January 21). VETERINARY PATHOLOGY, Vol. 1.

By: S. Fingerhood*, P. Neupane n, E. Breitschwerdt n & E. Choi*

Sources: Web Of Science, NC State University Libraries
Added: January 29, 2024

2024 journal article

Dilated cardiomyopathy of possible dietary origin in a cat

JOURNAL OF VETERINARY CARDIOLOGY, 51, 172–178.

By: B. Duperry*, K. Lopez*, J. Rush*, B. Berridge, R. Mitchell*, E. Breitschwerdt n, L. Freeman*

author keywords: Nutrition; Heart failure; Pulses; Feline; Electron microscopy
TL;DR: The relative roles of diet change, cardiac medications, and a dedicated owner are unclear, but this cat's relatively long survival time is similar to that seen after diet change in dogs and cats with DCM eating high-pulse diets. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 12, 2024

2024 article

Evaluation of the Veterinary IDEXX SNAP 4Dx Plus Test for the Diagnosis of Lyme Disease in Humans

Lee, G., Pretsch, P., Ursery, L., Giandomenico, D., Abernathy, H. A., Evans, L., … Boyce, R. M. (2024, June 19). VECTOR-BORNE AND ZOONOTIC DISEASES, Vol. 6.

By: G. Lee*, P. Pretsch*, L. Ursery*, D. Giandomenico*, H. Abernathy*, L. Evans*, B. Qurollo n, E. Breitschwerdt n, R. Boyce*

author keywords: Lyme disease; point-of-care; serology; diagnosis
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: July 1, 2024

2024 journal article

Human <i>Babesia odocoilei</i> and <i>Bartonella</i> spp. co-infections in the Americas

PARASITES & VECTORS, 17(1).

By: R. Maggi n, A. Calchi*, C. Moore n, E. Kingston n & E. Breitschwerdt n

author keywords: Bartonella; Babesiosis; Babesia odocoilei; Zoonotic diseases; Co-infection; Fatigue; Neurology
Sources: ORCID, Web Of Science, NC State University Libraries
Added: July 15, 2024

2024 journal article

Sequence typing of <i>Bartonella henselae</i> in small Indian mongooses (<i>Urva auropunctata</i>)

SCIENTIFIC REPORTS, 14(1).

By: A. Muller*, R. Maggi n, P. Sepulveda-Garcia*, A. Mau*, C. Sauve*, A. Conan, I. Branford*, P. Bittencourt*, E. Breitschwerdt n

Sources: Web Of Science, NC State University Libraries
Added: September 9, 2024

2024 review

Vector biology of the cat fl ea<i> Ctenocephalides felis</i>

[Review of ]. TRENDS IN PARASITOLOGY, 40(4), 324–337.

By: C. Moore n, M. Andre*, J. Slapeta* & E. Breitschwerdt n

TL;DR: Fundamental aspects of C. felis as a vector are reviewed with an emphasis on key techniques and research avenues employed in other vector species, improving the accuracy of vector and pathogen modeling to improve infection/infestation risk assessment and diagnostic recommendations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 8, 2024

2023 article

A second-generation, point-of-care immunoassay provided improved detection of Anaplasma and Ehrlichia antibodies in PCR-positive dogs naturally infected with Anaplasma or Ehrlichia species

Richardson, S. S., Mainville, C. A., Arguello-Marin, A., Whalley, D., Burton, W., Breitschwerdt, E. B., & Qurollo, B. A. (2023, May 9). JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION, Vol. 5.

By: S. Richardson n, C. Mainville*, A. Arguello-Marin*, D. Whalley*, W. Burton*, E. Breitschwerdt n, B. Qurollo n

author keywords: Anaplasma; dogs; Ehrlichia; immunoassay; point-of-care; serology; tick-borne pathogens
TL;DR: The second-generation SNAP 4Dx Plus test offered improved serologic detection of Anaplasma and Ehrlichia in naturally infected dogs, and case management decisions might have been different with an immediate anaplasmosis diagnosis, including earlier doxycycline therapy and less hospitalization. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: May 30, 2023

2023 article

Blood Supplementation Enhances Bartonella henselae Growth and Molecular Detection of Bacterial DNA in Liquid Culture

Liedig, C., Neupane, P., Lashnits, E., Breitschwerdt, E. B., & Maggi, R. G. (2023, May 25). (H. H. Mostafa, Ed.). MICROBIOLOGY SPECTRUM, Vol. 5.

By: C. Liedig n, P. Neupane*, E. Lashnits*, E. Breitschwerdt n & R. Maggi n

Ed(s): H. Mostafa

author keywords: BAPGM; Bartonella culture; Bartonella henselae; bartonellosis; blood supplementation; diagnostics
MeSH headings : Humans; Animals; Horses / genetics; Dogs; Sheep; Bartonella henselae / genetics; DNA, Bacterial / genetics; DNA, Bacterial / analysis; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella / genetics; Dietary Supplements; Mammals
TL;DR: The addition of sheep blood to liquid culture media increased the Bartonella henselae DNA concentration compared to controls, additionally improving PCR direct detection sensitivity. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: May 26, 2023

2023 journal article

Case report: Substantial improvement of autism spectrum disorder in a child with learning disabilities in conjunction with treatment for poly-microbial vector borne infections

FRONTIERS IN PSYCHIATRY, 14.

By: A. Offutt & E. Breitschwerdt n

author keywords: tics; infections; Bartonella; Lyme; PANS; OCD; autism; ADHD
TL;DR: Targeted antimicrobial treatment resulted in substantial improvement in cognitive and neurobehavioral symptoms in a boy diagnosed with autism spectrum disorder. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 18, 2023

2023 journal article

Eosinophilic pericardial effusion and pericarditis in a cat

JOURNAL OF FELINE MEDICINE AND SURGERY OPEN REPORTS, 9(2).

By: M. Wheatley n, J. Shamoun n, R. Maggi n, E. Breitschwerdt n, S. Sommer*, J. Cullen n, D. Stowe n

author keywords: Apicomplexan; Bartonella; eosinophilic effusion; mesothelial cells; pericardial effusion; pericarditis
TL;DR: This case offers several unique entities and illustrates the well-known marked atypia that may occur in reactive and hyperplastic mesothelial cells, particularly of infrequently sampled and cytologically described feline pericardial effusion, supporting a cautious interpretation of this cytology finding. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: December 18, 2023

2023 article

Establishment of a consensus protocol to explore the brain pathobiome in patients with mild cognitive impairment and Alzheimer's disease Research outline and call for collaboration

Lathe, R., Schultek, N. M., Balin, B. J., Ehrlich, G. D., Auber, L. A., Perry, G., … Tanzi, R. E. (2023, June 7). ALZHEIMERS & DEMENTIA, Vol. 6.

By: R. Lathe*, N. Schultek, B. Balin*, G. Ehrlich*, L. Auber, G. Perry*, E. Breitschwerdt n, D. Corry* ...

author keywords: Alzheimer's disease; antimicrobial; antiviral; bioinformatics; blood; cerebrospinal fluid; collaboration; dementia; diagnosis; methodology; microbiome; mild cognitive impairment; olfactory neuroepithelium; pathobiome; polymerase chain reaction; protocol; sequencing
TL;DR: The Alzheimer's Pathobiome Initiative aims to perform comparative molecular analyses of microbes in post mortem brains versus cerebrospinal fluid, blood, olfactory neuroepithelium, oral/nasopharyngeal tissue, bronchoalveolar, urinary, and gut/stool samples to provide a roadmap for detecting infectious agents in patients with mild cognitive impairment or AD. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: July 3, 2023

2023 journal article

Feeding on a Bartonella henselae Infected Host Triggers Temporary Changes in the Ctenocephalides felis Microbiome

PATHOGENS, 12(3).

By: C. Moore n, E. Lashnits n, P. Neupane n, B. Herrin*, M. Lappin*, M. Andre*, E. Breitschwerdt n

author keywords: Bartonella henselae; Ctenocephalides felis; flea; microbiome; wolbachia; vector microbiome
TL;DR: Using Next Generation Sequencing (NGS) on the Illumina platform, an increase in microbial diversity in C. felis microbiome when fed on B. henselae-infected cats is documented, which may be related to the mammalian, flea, or endosymbiont response. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 23, 2023

2023 article

Risk Factors for Bartonella Seroreactivity Among Veterinary Workers in the Pacific Northwest

Thiel, N., Baker, M., Lipton, B., Fuller, L., Breitschwerdt, E. B., & Rabinowitz, P. (2023, June 15). VECTOR-BORNE AND ZOONOTIC DISEASES, Vol. 6.

By: N. Thiel*, M. Baker*, B. Lipton*, L. Fuller, E. Breitschwerdt n & P. Rabinowitz*

author keywords: Bartonella henselae; Bartonella vinsonii; Bartonella koehlerae; risk matrix; zoonotic disease epidemiology; veterinarian occupational health
TL;DR: No significant predictors of seroreactivity were found, although the relationship between high-risk status and increased serore activity for some Bartonella species approached significance. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 26, 2023

2023 journal article

The association of host and vector characteristics with Ctenocephalides felis pathogen and endosymbiont infection

FRONTIERS IN MICROBIOLOGY, 14.

By: C. Moore n, E. Breitschwerdt n, L. Kim*, Y. Li*, K. Ferris n, R. Maggi n, E. Lashnits*

author keywords: Bartonella; flea; Wolbachia; vector phylogenetics; flea associated Rickettsia; host-vector agreement; cat flea
TL;DR: There was poor flea and host agreement for Bartonella spp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: April 4, 2023

2023 journal article

Viability and Desiccation Resistance of Bartonella henselae in Biological and Non-Biological Fluids: Evidence for Pathogen Environmental Stability

PATHOGENS, 12(7).

By: J. Bush n, R. Maggi n & E. Breitschwerdt n

author keywords: Bartonella; vector-borne; zoonotic; intracellular; alphaproteobacteria; desiccation; environment
TL;DR: The viability and stability of Bartonella within biological and non-biological fluids in the environment may represent a previously unrecognized source of infection for animals and human beings. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: July 20, 2023

2022 article

A bottom-up proteomics workflow for a system containing multiple organisms

Bai, H., Collins, L. B. B., Andre, M. R., Breitschwerdt, E. B. B., & Williams, T. I. (2023, January 3). RAPID COMMUNICATIONS IN MASS SPECTROMETRY, Vol. 1.

By: H. Bai n, L. Collins n, M. Andre n, E. Breitschwerdt n & T. Williams n

Contributors: H. Bai n, L. Collins n, M. André n, E. Breitschwerdt n & T. Williams n

TL;DR: A bottom-up proteomics workflow was developed to study a system containing multiple organisms to promote a thorough understanding of how each interacts with the others and can be readily applied to other label-free proteomics work involving multiple proteomes from taxonomically distinct organisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 25, 2022

2022 journal article

An Improved Point-of-Care ELISA for the Diagnosis of Anaplasmosis and Ehrlichiosis During the Acute Phase of Tick-Borne Infections in Dogs

TOPICS IN COMPANION ANIMAL MEDICINE, 51.

By: M. Beall*, C. Mainville*, A. Arguello-Marin*, G. Clark*, C. Lemieux*, J. Saucier*, B. Thatcher*, E. Breitschwerdt n ...

author keywords: Antibody; PCR; Serology; Infectious canine cyclic thrombocytopenia
MeSH headings : Dogs; Animals; Anaplasmosis; Point-of-Care Systems; Dirofilaria immitis; Dirofilariasis / diagnosis; Lyme Disease / diagnosis; Lyme Disease / veterinary; Antibodies, Bacterial; Dog Diseases; Ehrlichiosis / diagnosis; Ehrlichiosis / veterinary; Tick-Borne Diseases / veterinary; Ehrlichia; Enzyme-Linked Immunosorbent Assay / veterinary; Enzyme-Linked Immunosorbent Assay / methods
TL;DR: It is demonstrated that the second-generation POC ELISA had an improved ability to detect serologic responses during the acute phase of A. phagocytophilum, A. platys, and E. canis experimental infections. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: February 20, 2023

2022 journal article

Bartonella henselae Recombinant Pap31 for the Diagnosis of Canine and Human Bartonelloses

PATHOGENS, 11(2).

By: P. Neupane n, R. Maggi n, M. Basnet*, E. Lashnits*, G. Andrews* & E. Breitschwerdt n

author keywords: antigen; Bartonella henselae; serology; diagnosis; ELISA; Western blot; heme binding proteins
TL;DR: It is indicated that recombinant Pap31 and the selected fragments may not be appropriate diagnostic targets in detecting anti-Bartonella antibodies in Bartonella-infected dogs and humans. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 2, 2022

2022 journal article

Cat scratch disease: What to do with the cat?

American Journal of Ophthalmology Case Reports.

By: A. Smolar*, E. Breitschwerdt n, P. Phillips*, N. Newman* & V. Biousse*

TL;DR: When addressing the concerns of CSD patients in clinical practice, ophthalmologists should be aware of the strategies for minimizing Bartonella transmission risk, and cognizant of the One Health approach for managing zoonoses. (via Semantic Scholar)
Source: ORCID
Added: September 10, 2022

2022 article

FtlA and FtlB Are Candidates for Inclusion in a Next-Generation Multiantigen Subunit Vaccine for Lyme Disease

Camire, A. C., Nathaniel S. O'Bier, Patel, D. T., Cramer, N. A., Straubinger, R. K., Breitschwerdt, E. B., … Marconi, R. T. (2022, September 14). INFECTION AND IMMUNITY, Vol. 9.

By: A. Camire*, . Nathaniel S. O'Bier*, D. Patel*, N. Cramer*, R. Straubinger*, E. Breitschwerdt n, R. Funk*, R. Marconi*

author keywords: Borreliella; Borrelia; BBK01; BBG01; Ftl; Lyme disease vaccine; protein family 12; FtlA; Ixodes; Lyme vaccine; PF12; canine Lyme disease; chimeritope
MeSH headings : Animals; Dogs; Antibodies, Bacterial; Antigens, Bacterial; Bacterial Outer Membrane Proteins / genetics; Borrelia burgdorferi; Epitopes; Horses; Immune Sera; Ixodes / microbiology; Lipoproteins / genetics; Lyme Disease / microbiology; Vaccines, Combined; Vaccines, Subunit / genetics
TL;DR: It is suggested that FtlA and FtlB are potential candidates for inclusion in a multivalent vaccine for LD, and epitope localization revealed that the bactericidal epitopes reside within the N-terminal domain of the Ftl proteins. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: September 26, 2022

2022 journal article

Prospective serological and molecular cross-sectional study focusing on Bartonella and other blood-borne organisms in cats from Catalonia (Spain)

PARASITES & VECTORS, 15(1).

By: A. Alvarez-Fernandez*, R. Maggi n, G. Eduard Martin-Valls, M. Baxarias*, E. Bealmear Breitschwerdt & L. Solano-Gallego*

author keywords: Bartonellosis; Hemotropic Mycoplasma; Mycoplasma wenyonii; Ehrlichia; Anaplasma; Piroplasma; Co-infection; Cats; Spain
MeSH headings : Animals; Antibodies, Bacterial / blood; Antigens, Bacterial / immunology; Bartonella / genetics; Bartonella / immunology; Bartonella Infections / blood; Bartonella Infections / epidemiology; Bartonella Infections / transmission; Bartonella Infections / veterinary; Cat Diseases / blood; Cat Diseases / epidemiology; Cat Diseases / microbiology; Cat Diseases / transmission; Cats; Cross-Sectional Studies; DNA, Bacterial / blood; DNA, Bacterial / isolation & purification; DNA, Ribosomal Spacer / chemistry; Female; Fluorescent Antibody Technique / veterinary; Male; Polymerase Chain Reaction / veterinary; Prevalence; Prospective Studies; RNA, Ribosomal, 16S / genetics; RNA, Ribosomal, 23S / genetics; Real-Time Polymerase Chain Reaction / veterinary; Seroepidemiologic Studies; Spain / epidemiology
TL;DR: This study is the first to document M. wenyonii is infection in cats, and substantial to almost perfect serological agreement was found between the three Bartonella species. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 18, 2022

2022 journal article

Rickettsia typhi infection in a clinically-ill dog from Houston, Texas

VETERINARY PARASITOLOGY- REGIONAL STUDIES AND REPORTS, 35.

By: N. Juhasz n, J. Wilson n, K. Haney n, M. Clark*, A. Davenport*, E. Breitschwerdt n, B. Qurollo n

author keywords: Dog; Rickettsia typhi; Murine typhus; North America
MeSH headings : Animals; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dogs; Doxycycline / therapeutic use; Polymerase Chain Reaction / veterinary; Rickettsia typhi; Texas; Typhus, Endemic Flea-Borne / diagnosis; Typhus, Endemic Flea-Borne / drug therapy; Typhus, Endemic Flea-Borne / veterinary
TL;DR: In 2020, Rickettsia typhi was diagnosed in a dog from Houston, Texas, USA based upon R. typhi IFA seroreactivity in both acute and convalescent sera, and PCR with DNA sequencing of 4 different gene regions, all of which were 100% identical to R. Typhi. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 11, 2022

2022 journal article

Using Proteomic Approaches to Unravel the Response of Ctenocephalides felis felis to Blood Feeding and Infection With Bartonella henselae

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 12.

By: M. Andre n, P. Neupane n, M. Lappin*, B. Herrin*, V. Smith*, T. Williams n, L. Collins n, H. Bai n ...

Contributors: M. André n, P. Neupane n, M. Lappin*, B. Herrin*, V. Smith*, T. Williams n, L. Collins n, H. Bai n ...

author keywords: bartonellosis; cat flea; cat scratch disease; flea-pathogen interface; proteome
MeSH headings : Animals; Bartonella henselae / genetics; Cat Diseases; Cats; Ctenocephalides; Felis; Proteomics; Siphonaptera
TL;DR: Flea-differentially abundant proteins (FDAP) are investigated in unfed fleas, fleas fed on uninfected cats, and flea fed on B. henselae-infected cats to help understand the complex interactions between cat fleas and B. Henselae over an infection time course, thus helping understand the dual effect of vaccine targeting both flea fitness and pathogen competence. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: January 29, 2022

2022 article

Vector-borne disease and its relationship to hematologic abnormalities and microalbuminuria in retired racing and show-bred greyhounds

Kidd, L., Hamilton, H., Stine, L., Qurollo, B., & Breitschwerdt, E. B. (2022, July 11). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 7.

By: L. Kidd*, H. Hamilton*, L. Stine*, B. Qurollo n & E. Breitschwerdt n

author keywords: Babesia; Bartonella; Ehrlichia thrombocytopenia; hemotropic Mycoplasma; leukopenia; proteinuria
MeSH headings : Anaplasma; Animals; Babesia; Bartonella; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Ehrlichia canis; Mycoplasma; Proteinuria / veterinary; Thrombocytopenia / epidemiology; Thrombocytopenia / veterinary; Vector Borne Diseases / veterinary
TL;DR: The prevalence of thrombocytopenia and B. vogeli exposure was lower than previously documented and larger studies investigating the health impact of multiple VBD organisms are warranted. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: July 26, 2022

2021 journal article

Bartonella henselae Antibodies in Serum and Oral Fluid Specimens from Cats

PATHOGENS, 10(3).

By: A. Alvarez-Fernandez*, M. Baxarias*, D. Prandi*, E. Breitschwerdt n & L. Solano-Gallego*

author keywords: bartonellosis; feline; serology; immunofluorescence antibody assay; oral fluid
TL;DR: B. henselae OF IFA antibody measurements were less sensitive compared to serum IFA measurements of ≥1:64, therefore, OF antibodies, detectable by IFA, is of limited utility for epidemiological or diagnostic testing in cats. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 12, 2021

2021 journal article

Bartonella henselae Detected in Malignant Melanoma, a Preliminary Study

PATHOGENS, 10(3).

By: M. Ericson*, E. Breitschwerdt n, P. Reicherter*, C. Maxwell*, R. Maggi n, R. Melvin*, A. Maluki*, J. Bradley n ...

author keywords: melanoma; A375 cells; Bartonella spp; Bartonella henselae; vector-borne pathogens; multi-immunostaining methods; confocal microscopy of thick sections; cancer microbiome; melanoma pathobiome
TL;DR: Findings from this small number of patients support the need for future investigations to determine the extent to which Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 11, 2021

2021 article

Bartonella spp. seroepidemiology and associations with clinicopathologic findings in dogs in the United States

Lashnits, E., Thatcher, B., Carruth, A., Mestek, A., Buch, J., Beall, M., … Breitschwerdt, E. B. (2021, November 17). JOURNAL OF VETERINARY INTERNAL MEDICINE, Vol. 11.

By: E. Lashnits n, B. Thatcher*, A. Carruth*, A. Mestek*, J. Buch*, M. Beall*, P. Neupane n, R. Chandrashekar*, E. Breitschwerdt n

author keywords: bartonellosis; canine; seroreactivity; vector-borne; zoonoses
MeSH headings : Animals; Bartonella; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Dog Diseases / epidemiology; Dogs; Retrospective Studies; Seroepidemiologic Studies; United States / epidemiology
TL;DR: Demographic and geographic findings for Bartonella spp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 18, 2021

2021 journal article

Comparison of Serological and Molecular Assays for Bartonella Species in Dogs with Hemangiosarcoma

PATHOGENS, 10(7).

By: E. Lashnits n, P. Neupane n, J. Bradley n, T. Richardson n, R. Maggi n & E. Breitschwerdt n

author keywords: diagnostic testing; ddPCR; PCR; serology; sensitivity; specificity; tissue biopsy; latent class analysis
TL;DR: Data indicate that Bartonella spp. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: June 24, 2021

2021 journal article

Demographics and travel history of imported and autochthonous cases of leishmaniosis in dogs in the United States and Canada, 2006 to 2019

JOURNAL OF VETERINARY INTERNAL MEDICINE, 35(2), 954–964.

By: T. Gin n, E. Lashnits n, J. Wilson n, E. Breitschwerdt n & B. Qurollo n

author keywords: dog; leishmania; lutzomyia
MeSH headings : Animals; Canada / epidemiology; Demography; Dog Diseases / epidemiology; Dogs; Leishmania infantum; Retrospective Studies; Seroepidemiologic Studies; United States / epidemiology
TL;DR: Leishmania surveillance should be considered for dogs that return from L. infantum‐endemic regions to monitor emergence of this zoonotic disease in the US and Canada, and several nonfoxhound breeds had no travel history. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 27, 2021

2021 journal article

Development of a Multiplex Droplet Digital PCR Assay for the Detection of Babesia, Bartonella, and Borrelia Species

PATHOGENS, 10(11).

By: R. Maggi n, E. Breitschwerdt n, B. Qurollo n & J. Miller*

author keywords: Babesia; Bartonella; Borrelia; Cytauxzoon; Piroplasma; Theileria; clinical diagnostics; molecular detection; digital droplet PCR; digital PCR
TL;DR: The ddPCR assay facilitated the simultaneous detection of co-infections with two and three vector-borne pathogens comprising four different genera (Babesia, Bartonella, Borrelia, and Theileria) from clinical and other sample sources. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 12, 2021

2021 journal article

Exposure of Domestic Cats to Three Zoonotic Bartonella Species in the United States

PATHOGENS, 10(3).

By: L. Osikowicz*, K. Horiuchi*, I. Goodrich*, E. Breitschwerdt n, B. Chomel*, B. Biggerstaff*, M. Kosoy

author keywords: domestic cats; cat scratch disease; Bartonella henselae; Bartonella clarridgeiae; Bartonella koehlerae; serosurvey; IFA; vector-borne pathogens
TL;DR: Cat-associated Bartonella species, which include B. henselae, B. koehlerae, and B. clarridgeiae, can cause mild to severe illness in humans, and seroreactivity against three species and two strain types associated with cats was evaluated across the U.S. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 17, 2021

2021 article

Haematological and biochemical abnormalities in hunting dogs infected with Acanthocheilonema reconditum, associated risk factors, and a European overview

Pacifico, L., Ferrari, N., Romeo, C., Buono, F., Varuzza, P., Sgroi, G., … Piantedosi, D. (2021, May 8). PARASITOLOGY RESEARCH, Vol. 5.

By: L. Pacifico*, N. Ferrari*, C. Romeo*, F. Buono*, P. Varuzza*, G. Sgroi*, B. Neola*, J. Buch* ...

author keywords: Filarial nematodes; Acanthocheilonema spp; CVBDs; Hunting dogs
MeSH headings : Acanthocheilonema / isolation & purification; Acanthocheilonema / pathogenicity; Acanthocheilonemiasis / blood; Acanthocheilonemiasis / epidemiology; Acanthocheilonemiasis / parasitology; Acanthocheilonemiasis / veterinary; Animals; Dog Diseases / blood; Dog Diseases / epidemiology; Dog Diseases / parasitology; Dogs; Hematologic Diseases / blood; Hematologic Diseases / epidemiology; Hematologic Diseases / parasitology; Hematologic Diseases / veterinary; Italy / epidemiology; Male; Microfilariae / isolation & purification; Microfilariae / pathogenicity; Prevalence; Risk Factors; Working Dogs / parasitology
TL;DR: The results showed that A. reconditum circulates within the hunting dog population of southern Italy, with seemingly low pathogenic potential. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: June 10, 2021

2021 journal article

Prevalence of Vector-Borne Pathogens in Reproductive and Non-Reproductive Tissue Samples from Free-Roaming Domestic Cats in the South Atlantic USA

PATHOGENS, 10(9).

By: C. Manvell n, K. Ferris n, R. Maggi n, E. Breitschwerdt n & E. Lashnits n

author keywords: Bartonella spp; hemotropic Mycoplasma spp; reproduction; cats; prevalence
TL;DR: Ear tip and reproductive tissues of FRCs from two locations in the South Atlantic United States for Anaplasma, Bartonella, Ehrlichia, hemotropic Mycoplasma, and Rickettsia species suggest that B. henselae preferentially infected cats’ reproductive tissue and reinforces the importance of investigating the potential for vertical transmission or induction of reproductive failure. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: September 22, 2021

2021 review

Recent Progress in Lyme Disease and Remaining Challenges

[Review of ]. FRONTIERS IN MEDICINE, 8.

author keywords: Lyme disease; pathogenesis; diagnosis; treatment; prevention; field building; PTLD; vaccine
TL;DR: Progress over the past 5 years in the understanding of Lyme and tick-borne diseases in the United States is summarized and remaining challenges are highlighted. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: September 20, 2021

2021 journal article

Schizophrenia and Bartonella spp. Infection: A Pilot Case-Control Study

VECTOR-BORNE AND ZOONOTIC DISEASES, 21(6), 413–421.

By: E. Lashnits n, R. Maggi n, F. Jarskog*, J. Bradley n, E. Breitschwerdt n & F. Frohlich*

author keywords: vector-borne disease; infectious disease; cat; epidemiology; ddPCR; cat scratch disease
MeSH headings : Animals; Bartonella / genetics; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Case-Control Studies; Pilot Projects; Schizophrenia
TL;DR: Preliminary evidence in support of future investigations that should examine a potential contribution of Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: April 5, 2021

2021 journal article

Suspected Bartonella osteomyelitis in a dog

CLINICAL CASE REPORTS, 9(7).

By: F. Easley n, L. Taylor & E. Breitschwerdt n

author keywords: bone; infection; kidney; polydipsia and polyuria
TL;DR: Infection with Bartonella spp. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: July 22, 2021

2020 journal article

A retrospective study of vector‐borne disease prevalence in dogs with proteinuria: Southeastern United States

Journal of Veterinary Internal Medicine, 1.

By: E. Purswell n, E. Lashnits n, E. Breitschwerdt n & S. Vaden n

author keywords: anaplasmosis; ehrlichiosis; flea; immune-mediated; rickettsioses; tick
MeSH headings : Animals; Cross-Sectional Studies; Dog Diseases / epidemiology; Dog Diseases / etiology; Dogs; Female; Male; Prevalence; Proteinuria / veterinary; Retrospective Studies; Risk Factors; Seasons; Southeastern United States / epidemiology; Vector Borne Diseases / epidemiology; Vector Borne Diseases / veterinary
TL;DR: Exposure to CVBD, particularly exposure to Rickettsia spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: January 9, 2020

2020 journal article

Bartonella Associated Cutaneous Lesions (BACL) in People with Neuropsychiatric Symptoms

Pathogens, 9(12), 1023.

By: E. Breitschwerdt n, J. Bradley n, R. Maggi n, E. Lashnits n & P. Reicherter*

author keywords: infection; bacteria; psychoses; transmission; stretch marks; bartonella; neuropsychiatric; cutaneous lesions; BACL
TL;DR: It is concluded that cutaneous lesions were common among people reporting neuropsychiatric symptoms and Bartonella spp. (via Semantic Scholar)
Source: ORCID
Added: December 5, 2020

2020 journal article

Bartonella rochalimae, a newly recognized pathogen in dogs

Journal of Veterinary Internal Medicine.

By: E. Ernst n, B. Qurollo n, C. Olech n & E. Breitschwerdt n

author keywords: emerging; endocarditis; infection; polymerase chain reaction; vector-borne
MeSH headings : Animals; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Endocarditis, Bacterial / veterinary; Female; Lameness, Animal; Male; Polymerase Chain Reaction / veterinary; Retrospective Studies; Seizures / veterinary; United States
TL;DR: A spectrum of clinical presentations accompanied by mild hematological abnormalities in B rochalimae‐infected dogs from the United States is documented to provide support for an association between B rochardimae and IE and provides documentation of dogs infected with B ro Chalimae with other clinical diagnoses. (via Semantic Scholar)
Source: ORCID
Added: May 17, 2020

2020 journal article

Bartonella spp. Prevalence (Serology, Culture, and PCR) in Sanitary Workers in La Rioja Spain

Pathogens, 9(3), 189.

author keywords: Bartonella Alpha-Proteobacteria Growth Medium (BAPGM); B. henselae; B. quintana; B. vinsonii subsp. berkhoffii; B. koehlerae; sanitary workers
TL;DR: The results suggest that exposure to and non-clinical infection with Bartonella spp. (via Semantic Scholar)
Source: ORCID
Added: March 7, 2020

2020 journal article

Development and validation of a droplet digital PCR assay for the detection and quantification of Bartonella species within human clinical samples

JOURNAL OF MICROBIOLOGICAL METHODS, 176.

By: R. Maggi n, T. Richardson*, E. Breitschwerdt n & J. Miller*

author keywords: Bartonella; Clinical diagnostics; Molecular detection; Digital droplet PCR; Digital PCR
MeSH headings : Bacteremia / diagnosis; Bacteremia / microbiology; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; DNA, Bacterial / isolation & purification; Humans; Real-Time Polymerase Chain Reaction / methods
TL;DR: The ddPCR assay developed based upon previously published TaqMan-based qPCR assays that can amplify DNA of over 25 Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: October 5, 2020

2020 journal article

Distribution and risk factors of canine haemotropic mycoplasmas in hunting dogs from southern Italy

VETERINARY MICROBIOLOGY, 251.

By: L. Cortese*, M. Beall*, F. Buono*, J. Buch*, L. Pacifico*, B. Neola*, A. Palatucci*, P. Tyrrell* ...

author keywords: Mycoplasma haemocanis; Candidatus mycoplasma haematoparvum; Hunting dogs; Italy
MeSH headings : Animals; DNA, Bacterial / genetics; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Female; Italy / epidemiology; Male; Mycoplasma / classification; Mycoplasma / genetics; Mycoplasma / isolation & purification; Mycoplasma / pathogenicity; Mycoplasma Infections / epidemiology; Mycoplasma Infections / veterinary; Prevalence; RNA, Ribosomal, 16S / genetics; Risk Factors; Tick Infestations / veterinary; Working Dogs / microbiology
TL;DR: Outdoor lifestyle and contact with wild fauna, through greater exposure to tick infestation, or possibly wounds acquired during hunting or fighting, could be factors contributing to haemoplasma infections. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: January 19, 2021

2020 journal article

Ehrlichia chaffeensis EplA Interaction With Host Cell Protein Disulfide Isomerase Promotes Infection

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 10.

By: R. Green*, J. Izac*, W. Naimi*, N. O'Bier*, E. Breitschwerdt n, R. Marconi*, J. Carlyon*

author keywords: Ehrlichia; protein disulfide isomerase; Intracellular bacteria; bacterial invasion; adhesin; anaplamataceae
MeSH headings : Adhesins, Bacterial; Animals; Dogs; Ehrlichia chaffeensis; Ehrlichiosis; Monocytes; Protein Disulfide-Isomerases
TL;DR: EplA contributes to E. chaffeensis infection of monocytic cells by engaging PDI and exploiting the enzyme's reduction of host cell surface disulfide bonds in an EplA C-terminus-dependent manner and is identified as a novel ehrlichial receptor binding domains. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: October 26, 2020

2020 journal article

Hepatozoon canisin hunting dogs from Southern Italy: distribution and risk factors

PARASITOLOGY RESEARCH, 119(9), 3023–3031.

By: L. Pacifico*, J. Braff*, F. Buono*, M. Beall*, B. Neola*, J. Buch*, G. Sgroi*, D. Piantedosi* ...

author keywords: Hepatozoon canis; Hunting dogs; Vector-borne diseases; Italy; PCR
TL;DR: The aims of the present survey were to determine the prevalence of H. canis in hunting dogs living in Southern Italy and to assess potential infection risk factors, as well as to assess the epidemiological relationships between hunting dogs and wild animal populations sharing the same habitats in SouthernItaly. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 17, 2020

2020 journal article

Imaging analysis of Bartonella species in the skin using single‐photon and multi‐photon (second harmonic generation) laser scanning microscopy

Clinical Case Reports.

By: A. Maluki*, E. Breitschwerdt n, L. Bemis*, R. Greenberg*, B. Mozayeni, J. Dencklau*, M. Ericson*

author keywords: Bartonella; confocal microscopy; psychiatric disorders; second harmonic generation; striae distensae
TL;DR: It is demonstrated Bartonella spp are abundant in skin lesions resembling striae distensae, coincidental with sudden onset of neuropsychiatric symptoms, indicate testing for suspected Bartonelli spp. (via Semantic Scholar)
Source: ORCID
Added: July 20, 2020

2020 journal article

Molecular prevalence of Bartonella, Babesia, and hemotropic Mycoplasma species in dogs with hemangiosarcoma from across the United States

PLOS ONE.

Ed(s): D. Thamm

MeSH headings : Animals; Babesia / genetics; Babesiosis / epidemiology; Babesiosis / parasitology; Bartonella / genetics; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; DNA, Bacterial / genetics; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Female; Hemangiosarcoma / epidemiology; Hemangiosarcoma / microbiology; Hemangiosarcoma / parasitology; Hemangiosarcoma / veterinary; Male; Mycoplasma / genetics; Mycoplasma Infections / epidemiology; Mycoplasma Infections / veterinary; Polymerase Chain Reaction; Prevalence; Retrospective Studies; United States / epidemiology
TL;DR: A high prevalence of Bartonella spp. (via Semantic Scholar)
Source: ORCID
Added: January 11, 2020

2020 journal article

Novel Rickettsia Species Infecting Dogs, United States

EMERGING INFECTIOUS DISEASES, 26(12), 3011–3015.

By: J. Wilson n, E. Breitschwerdt n, N. Juhasz n, H. Marr n, J. Galvao n, C. Pratt n, B. Qurollo n

MeSH headings : Animals; Dog Diseases / epidemiology; Dogs; Phylogeny; Rickettsia / genetics; Rickettsia Infections / epidemiology; Rickettsia Infections / veterinary; United States / epidemiology
TL;DR: Multilocus phylogenetic analysis showed the dogs were infected with a novel Rickettsia species related to humanRickettsia pathogens. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: February 15, 2021

2020 journal article

Validation of Bartonella henselae Western Immunoblotting for Serodiagnosis of Bartonelloses in Dogs

JOURNAL OF CLINICAL MICROBIOLOGY, 58(4).

By: P. Neupane n, S. Sevala n, N. Balakrishnan*, H. Marr n, J. Wilson n, R. Maggi n, A. Birkenheuer n, M. Lappin*, B. Chomel*, E. Breitschwerdt n

author keywords: serology; zoonosis; vector borne; Western blotting; antigen; Bartonella henselae
MeSH headings : Animals; Antibodies, Bacterial; Bartonella; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; Bartonella henselae; Blotting, Western; Dog Diseases / diagnosis; Dogs; Serologic Tests
TL;DR: This study characterized WB immunodominant proteins that could be used to confirm a serodiagnosis of canine bartonelloses using agar-grown Bartonella henselae San Antonio type 2 (SA2) whole-cell proteins, and found a strong but variable recognition of these proteins among 81% of group II dogs. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 27, 2020

2019 review

An update on the treatment of canine monocytic ehrlichiosis (Ehrlichia canis)

[Review of ]. VETERINARY JOURNAL, 246, 45–53.

By: M. Mylonakis*, S. Harrus* & E. Breitschwerdt n

author keywords: Aplastic pancytopenia; Canine monocytic ehrlichiosis; Dog; Ehrlichia canis; Treatment
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Dog Diseases / drug therapy; Dogs; Ehrlichia canis; Ehrlichiosis / complications; Ehrlichiosis / drug therapy; Ehrlichiosis / veterinary; Pancytopenia / etiology; Pancytopenia / veterinary; Treatment Outcome
TL;DR: The current state of knowledge regarding treatment of ehrlichiosis, caused by E. canis infection in dogs, is reviewed, expert opinion guidelines for the management of the CME-associated aplastic pancytopenia are provided, and methods for evaluation of treatment outcomes are outlined. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 15, 2019

2019 journal article

Analysis of the antigenic determinants of the OspC protein of the Lyme disease spirochetes: Evidence that the C10 motif is not immunodominant or required to elicit bactericidal antibody responses

Vaccine, 37(17), 2401–2407.

By: J. Izac n, A. Camire n, C. Earnhart n, M. Embers n, R. Funk n, E. Breitschwerdt n, R. Marconi n

author keywords: Borreliella; Lyme disease; OspC; Lyme disease vaccine; Borrelia
MeSH headings : Animals; Antibodies, Bacterial / blood; Antibodies, Bacterial / immunology; Antibody Formation; Antigens, Bacterial / immunology; Bacterial Outer Membrane Proteins / immunology; Borrelia burgdorferi / immunology; Dogs; Enzyme-Linked Immunosorbent Assay; Epitopes / immunology; Horses; Humans; Lyme Disease / immunology; Lyme Disease / prevention & control; Primates; Rabbits; Recombinant Proteins / immunology; Vaccination
TL;DR: Insight is provided into the antigenic structure of OspC and it is demonstrated that the C10 motif does not significantly contribute to immunization or infection induced Ab responses in rabbits, rats, canines, horses and non-human primates. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: May 20, 2019

2019 journal article

Bartonella henselae Bloodstream Infection in a Boy With Pediatric Acute-Onset Neuropsychiatric Syndrome

Journal of Central Nervous System Disease, 11, 117957351983201.

By: E. Breitschwerdt n, R. Greenberg*, R. Maggi n, B. Mozayeni, A. Lewis & J. Bradley n

author keywords: Bacteria; psychosis; transmission; stretch marks; Bartonella; schizophrenia
TL;DR: This case report suggests that B henselae bloodstream infection may contribute to progressive, recalcitrant neuropsychiatric symptoms consistent with PANS in a subset of patients. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: April 9, 2019

2019 journal article

Clinicopathological findings in 41 dogs (2008‐2018) naturally infected with Ehrlichia ewingii

Journal of Veterinary Internal Medicine, 33(2), 618–629.

By: B. Qurollo n, J. Buch*, R. Chandrashekar*, M. Beall*, E. Breitschwerdt n, C. Yancey*, A. Caudill n, A. Comyn n

author keywords: canine; granulocytic ehrlichiosis; tick borne
MeSH headings : Animals; Antibodies, Bacterial / blood; Blood Cell Count / veterinary; Borrelia burgdorferi / immunology; Dog Diseases / blood; Dog Diseases / diagnosis; Dogs; Ehrlichia / immunology; Ehrlichia canis / immunology; Ehrlichiosis / diagnosis; Ehrlichiosis / veterinary; Female; Male; Retrospective Studies; Serologic Tests / veterinary
TL;DR: Renal disease, IMHA, proteinuria, neutrophilia, abnormal lymphocytes, and increased liver enzyme activities were common in this group of E. ewingii‐infected dogs and studies are needed to determine if E. Ewingii contributes to comorbidities or is a precipitating factor in clinical syndromes in persistently infected dogs. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: April 22, 2019

2019 journal article

Detection of Bartonella spp. in dogs after infection with Rickettsia rickettsii

Journal of Veterinary Internal Medicine, 34(1), 145–159.

By: E. Lashnits n, P. Neupane n, R. Maggi n, K. Linder n, J. Bradley n, N. Balakrishnan n, B. Southern n, G. McKeon n, R. Chandrashekar*, E. Breitschwerdt n

author keywords: PCR; recrudescence; serology; transmission
MeSH headings : Animals; Bartonella / isolation & purification; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Coinfection; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Female; Housing, Animal; Laboratory Animal Science; Rickettsia rickettsii; Rocky Mountain Spotted Fever / complications; Rocky Mountain Spotted Fever / microbiology; Rocky Mountain Spotted Fever / veterinary; Serologic Tests
TL;DR: The results support the possibilities of recrudescence of chronic subclinical Bartonella spp. (via Semantic Scholar)
Source: ORCID
Added: January 1, 2020

2019 journal article

Ecological and Socioeconomic Factors Associated with Bartonella henselae Exposure in Dogs Tested for Vector-Borne Diseases in North Carolina

Vector-Borne and Zoonotic Diseases, 19(8), 582–595.

By: E. Lashnits n, D. Dawson n, E. Breitschwerdt n & C. Lanzas n

author keywords: canine; seroreactivity; tick; flea; zoonoses; vector-borne
MeSH headings : Animals; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Bartonella henselae; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Ecosystem; Female; Male; North Carolina / epidemiology; Retrospective Studies; Risk Factors; Seroepidemiologic Studies; Socioeconomic Factors; Tick-Borne Diseases / epidemiology
TL;DR: Of 25 explanatory factors considered, the model combining demographic, socioeconomic, climatic, and land use variables fits best, and female intact sex and increasing percentage of the county with low-intensity development and evergreen forest were associated with higher seroreactivity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: June 4, 2019

2019 journal article

Evidence for vertical transmission of Mycoplasma haemocanis, but not Ehrlichia ewingii, in a dog

Journal of Veterinary Internal Medicine, 33(4), 1747–1752.

By: E. Lashnits n, S. Grant, B. Thomas n, B. Qurollo n & E. Breitschwerdt n

author keywords: bacterial species; hemotropic mycoplasma; perinatal; rickettsia; vector-borne
MeSH headings : Animals; Antibodies, Bacterial; Coinfection / veterinary; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Ehrlichia / isolation & purification; Ehrlichiosis / immunology; Ehrlichiosis / veterinary; Female; Infectious Disease Transmission, Vertical / veterinary; Male; Mycoplasma / isolation & purification; Mycoplasma Infections / transmission; Mycoplasma Infections / veterinary; Pregnancy
TL;DR: A potential role for vertical transmission in the maintenance of M. haemocanis in dogs as reservoir hosts is supported and there is no evidence that E. ewingii was transmitted transplacentally or during the perinatal period. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: May 27, 2019

2019 journal article

Molecular identification of vector-borne organisms in Ehrlichia seropositive Nicaraguan horses and first report of Rickettsia felis infection in the horse

ACTA TROPICA, 200.

By: J. Tyrrell n, B. Qurollo n, S. Tornquist*, K. Schlaich*, J. Kelsey*, R. Chandrashekar*, E. Breitschwerdt n

author keywords: Tick-borne disease; Equine rickettsiosis; Piroplasmosis; Babesia caballi; Theileria equi; Ehrlichia species H7
MeSH headings : Animals; Disease Vectors; Ehrlichia / genetics; Ehrlichia / isolation & purification; Ehrlichiosis / diagnosis; Ehrlichiosis / epidemiology; Horses / microbiology; Nicaragua / epidemiology; Rickettsia Infections / diagnosis; Rickettsia Infections / epidemiology; Rickettsia felis / genetics; Rickettsia felis / isolation & purification
TL;DR: To the authors' knowledge, this constitutes the first report of molecular detection of R. felis in horses. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: December 16, 2019

2019 article

My Mother's Story: Tick Borne Ehrlichiosis and a Life Well-Lived

Breitschwerdt, E. B., & Maggi, R. G. (2020, May 1). VECTOR-BORNE AND ZOONOTIC DISEASES, Vol. 20, pp. 319–324.

By: E. Breitschwerdt n & R. Maggi n

author keywords: Ehrlichia; Bartonella; dementia; one health; non-Hodgkin's lymphoma
MeSH headings : Aged, 80 and over; Animals; Anti-Bacterial Agents / therapeutic use; Doxycycline / therapeutic use; Ehrlichia; Ehrlichiosis / diagnosis; Ehrlichiosis / drug therapy; Ehrlichiosis / epidemiology; Ehrlichiosis / pathology; Female; Humans; Maryland / epidemiology; Tick Bites; Ticks
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: May 18, 2020

2019 journal article

Prevalence of Babesia spp. and clinical characteristics of Babesia vulpes infections in North American dogs

Journal of Veterinary Internal Medicine, 7.

By: N. Barash n, B. Thomas n, A. Birkenheuer n, E. Breitschwerdt n, E. Lemler n & B. Qurollo n

author keywords: B; vulpes; Babesia; hemolytic anemia; prevalence; tick; vector-borne disease
MeSH headings : Animals; Babesia / classification; Babesia / isolation & purification; Babesiosis / epidemiology; Babesiosis / transmission; Coinfection / veterinary; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dog Diseases / pathology; Dogs; North America / epidemiology; Polymerase Chain Reaction / veterinary; Prevalence
TL;DR: The prevalence of Babesia sp. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 5, 2019

2019 journal article

Pyogranulomatous Myocarditis and Diaphragmatic Myositis Associated with Bartonella Henselae in a Cat From Turkey

Ankara Üniversitesi Veteriner Fakültesi Dergisi, 66(1), 103–107.

By: M. Gulbahar, E. Karaca, A. Ciftci, S. Inal, I. Ahmed, N. Balakrishnan, E. Breitshwerdt

TL;DR: Evidence is provided in support of an etiological association between pyogranulomatous myocarditis and diaphragmatic myositis and B. henselae infection in cats. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 13, 2019

2019 journal article

Trait-performance relationships of grassland plant species differ between common garden and field conditions

Ecology and Evolution, 9(4), 1691–1701.

author keywords: common garden experiment; land-use; managed grassland; plant functional traits; plant performance; relative growth rates
TL;DR: The ability to reproduce vegetatively, having leaves that are summer‐persistent and with high leaf dry matter content were traits of major importance under both settings, albeit the magnitude of their influence differed slightly between the field and the common garden experiment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 8, 2019

2018 journal article

Babesia gibsoni cytochrome b mutations in canine blood samples submitted to a US veterinary diagnostic laboratory

Journal of Veterinary Internal Medicine, 32(6), 1965–1969.

By: A. Birkenheuer n, H. Marr n, J. Wilson n, E. Breitschwerdt n & B. Qurollo n

author keywords: atovaquone; mitochondrial; pharmacogenomics; resistance
MeSH headings : Animals; Babesia / genetics; Babesiosis / blood; Babesiosis / epidemiology; Babesiosis / parasitology; Cytochromes b / genetics; Dog Diseases / blood; Dog Diseases / epidemiology; Dog Diseases / parasitology; Dogs; Mutation / genetics; Pathology, Veterinary / statistics & numerical data; Prevalence; Real-Time Polymerase Chain Reaction / veterinary; United States / epidemiology
TL;DR: The study reaffirms that B. gibsoni infection is widespread and most commonly detected in American Staffordshire Terrier/American Pit Bull Terrier dogs and that the prevalence of cytb mutations does not warrant pretreatment genotyping. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: December 31, 2018

2018 journal article

Bartonella henselae in a dog with ear tip vasculitis

Veterinary Dermatology, 29(6), 537–e180.

By: B. Southern n, P. Neupane n, M. Ericson*, J. Dencklau*, K. Linder n, J. Bradley n, G. McKeon n, C. Long*, E. Breitschwerdt n

MeSH headings : Animals; Bartonella henselae / genetics; Cat-Scratch Disease / pathology; Cat-Scratch Disease / veterinary; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Ear, External / microbiology; Ear, External / pathology; Female; Polymerase Chain Reaction / veterinary; Vasculitis / diagnosis; Vasculitis / pathology; Vasculitis / veterinary
TL;DR: Bartonella henselae is an emerging zoonotic pathogen that has been associated with leucocytoclastic vasculitis in humans and may have had a contributing or causative role in the development of the cutaneous aural margin vasculopathy in this beagle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: November 26, 2018

2018 journal article

Bartonella henselae infection in a dog with recalcitrant ineffective erythropoiesis

Veterinary Clinical Pathology, 47(1), 45–50.

By: M. Randell, N. Balakrishnan n, R. Gunn-Christie, A. Mackin* & E. Breitschwerdt n

author keywords: Bartonella henselae; bone marrow dyscrasia; immunosuppression; ineffective erythropoiesis
TL;DR: The contribution of B henselae bacteremia to ineffective erythropoiesis remains unknown; however, the potential role of B Henselae in the pathophysiology of bone marrow dyscrasias warrants additional investigation. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2018 journal article

Bartonella henselae in small Indian mongooses ( Herpestes auropunctatus ) from Grenada, West Indies

Veterinary Microbiology, 216, 119–122.

By: D. Jaffe*, B. Chomel*, R. Kasten*, E. Breitschwerdt n, R. Maggi n, A. McLeish*, U. Zieger*

author keywords: Bartonella henselae; Herpestes auropunctatus; Small Indian mongoose; Grenada Island
MeSH headings : Angiomatosis, Bacillary / epidemiology; Angiomatosis, Bacillary / microbiology; Animals; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Bartonella henselae / physiology; Disease Reservoirs / microbiology; Genotype; Grenada / epidemiology; Herpestidae / microbiology; Zoonoses / epidemiology; Zoonoses / microbiology
TL;DR: The role of small Indian mongooses as a natural reservoir of B. henselae in the New World is confirmed and documented to identify a potential source of zoonotic risk with mongoose-human contact in theNew World. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2018 journal article

Bartonella infections in cats and dogs including zoonotic aspects

Parasites & Vectors, 11(1).

By: A. Álvarez-Fernández*, E. Breitschwerdt n & L. Solano-Gallego*

author keywords: Bartonella; Dog; Cat; Europe; Zoonosis
MeSH headings : Animals; Bartonella / classification; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / transmission; Bartonella Infections / veterinary; Cat Diseases / diagnosis; Cat Diseases / microbiology; Cat Diseases / pathology; Cat Diseases / therapy; Cats; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dog Diseases / pathology; Dog Diseases / therapy; Dogs; Europe / epidemiology; Humans; Prevalence; Zoonoses / epidemiology; Zoonoses / microbiology; Zoonoses / transmission
TL;DR: An update and European perspective on Bartonella infections in cats and dogs, including clinical, diagnostic, epidemiological, pathological, treatment and zoonotic aspects is provided. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: December 17, 2018

2018 journal article

Bartonella quintana and Bartonella vinsonii subsp. vinsonii bloodstream co-infection in a girl from North Carolina, USA

Medical Microbiology and Immunology, 208(1), 101–107.

By: E. Breitschwerdt n & R. Maggi n

author keywords: Bartonella quintana; Bartonella vinsonii subsp; vinsonii; Bacteria; Vector; Equestrian
MeSH headings : Adolescent; Bacteremia / diagnosis; Bacteremia / microbiology; Bacteremia / pathology; Bartonella / classification; Bartonella / genetics; Bartonella / isolation & purification; Bartonellaceae Infections / diagnosis; Bartonellaceae Infections / microbiology; Bartonellaceae Infections / pathology; Cluster Analysis; Coinfection / diagnosis; Coinfection / microbiology; Coinfection / pathology; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; DNA, Ribosomal Spacer / chemistry; DNA, Ribosomal Spacer / genetics; Female; Humans; Microbiological Techniques; Molecular Diagnostic Techniques; North Carolina; Phylogeny; Sequence Analysis, DNA; Serologic Tests
TL;DR: The first documented human case of blood stream infection with Bartonella vinsonii subsp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: February 4, 2019

2018 journal article

Bartonella spp. Bloodstream Infection in a Canadian Family

Vector-Borne and Zoonotic Diseases, 19(4), 234–241.

By: E. Breitschwerdt n, R. Maggi n, C. Quach* & J. Bradley n

author keywords: infection; bacteria; family; transmission; vectors
MeSH headings : Adult; Bacteremia / microbiology; Bartonella / genetics; Bartonella / isolation & purification; Bartonella Infections / microbiology; Canada; Child; Family; Female; Humans; Male; Real-Time Polymerase Chain Reaction
TL;DR: There is a substantial need for clinical research to clarify the extent to which Bartonella spp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: April 15, 2019

2018 journal article

Bartonella spp. as a Possible Cause or Cofactor of Feline Endomyocarditis–Left Ventricular Endocardial Fibrosis Complex

Journal of Comparative Pathology, 162, 29–42.

By: T. Donovan*, N. Balakrishnan*, I. Carvalho Barbosa, T. McCoy n, E. Breitschwerdt n & P. Fox*

author keywords: Barlonella; cat; endocardial fibrosis; endomyocarditis
MeSH headings : Animals; Bartonella; Bartonella Infections / veterinary; Cat Diseases / microbiology; Cats; DNA, Bacterial / analysis; Endocarditis, Bacterial / veterinary; Myocarditis / veterinary
TL;DR: The hypothesis that Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries
Added: September 11, 2019

2018 journal article

Comparative Evaluation of 2 In-Clinic Assays for Vector-Borne Disease Testing in Dogs

TOPICS IN COMPANION ANIMAL MEDICINE, 33(4), 114–118.

By: J. Liu*, J. Drexel*, B. Andrews*, M. Eberts*, E. Breitschwerdt n & R. Chandrashekar*

author keywords: SNAP 4Dx plus; FLEX4; tick-borne disease; heartworm disease; in-clinic assays; serology
MeSH headings : Anaplasma / immunology; Anaplasmosis / blood; Anaplasmosis / diagnosis; Animals; Antibodies, Bacterial / blood; Antibodies, Helminth / blood; Borrelia burgdorferi / immunology; Dirofilaria immitis / immunology; Dirofilariasis / diagnosis; Dog Diseases / blood; Dog Diseases / diagnosis; Dogs; Ehrlichia / immunology; Ehrlichiosis / blood; Ehrlichiosis / diagnosis; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay / methods; Enzyme-Linked Immunosorbent Assay / veterinary; Lyme Disease / blood; Lyme Disease / diagnosis; Lyme Disease / veterinary; Sensitivity and Specificity; Tick-Borne Diseases / diagnosis; Tick-Borne Diseases / veterinary
TL;DR: Based upon the comparative results derived from this study, the SNAP test was more sensitive than the FLEX4 test for detection of antibodies to all tick‐borne pathogens and heartworm disease (Dirofilaria immitis) antigen in dogs. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 21, 2019

2018 journal article

Distribution and risk factors associated with Babesia spp. infection in hunting dogs from Southern Italy

TICKS AND TICK-BORNE DISEASES, 9(6), 1459–1463.

By: V. Veneziano*, D. Piantedosi*, N. Ferrari*, B. Neola*, M. Santoro*, L. Pacifico*, G. Sgroi*, N. D'Alessio* ...

author keywords: Babesia canis; Babesia vogeli; Babesia gibsoni; Hunting dogs; Italy
MeSH headings : Animals; Babesia / classification; Babesia / isolation & purification; Babesia / physiology; Babesiosis / epidemiology; Babesiosis / parasitology; Dog Diseases / epidemiology; Dog Diseases / parasitology; Dogs; Italy / epidemiology; Prevalence; Risk Factors; Seroepidemiologic Studies
TL;DR: The aim of this survey was to determine the prevalence and risk factors associated with Babesia species infections in hunting dogs from Southern Italy, and to evaluate the potential epidemiological relationships between hunting dogs and wild animal populations sharing the same area. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: October 16, 2018

2018 journal article

Evaluation of cell culture-grown Bartonella antigens in immunofluorescent antibody assays for the serological diagnosis of bartonellosis in dogs

Journal of Veterinary Internal Medicine, 32(6), 1958–1964.

By: P. Neupane n, B. Hegarty n, H. Marr n, R. Maggi n, A. Birkenheuer n & E. Breitschwerdt n

author keywords: bacteria; BAPGM; serology; vector-borne; zoonosis
MeSH headings : Animals; Antigens, Bacterial / immunology; Bartonella / immunology; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; Bartonella henselae / immunology; Bartonella quintana / immunology; Cells, Cultured; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Fluorescent Antibody Technique / methods; Fluorescent Antibody Technique / veterinary; Polymerase Chain Reaction / veterinary; Sensitivity and Specificity; Serologic Tests / methods; Serologic Tests / veterinary; Trench Fever / diagnosis; Trench Fever / veterinary
TL;DR: Despite IFA testing of dogs against 8 different Bartonella isolates, IFA sensitivity remained poor, and specificity was only 85%. (via Semantic Scholar)
UN Sustainable Development Goal Categories
1. No Poverty (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: December 31, 2018

2018 journal article

Identification of Hemotropic Mycoplasmas in an Eastern Box Turtle (Terrapene carolina carolina) and a Yellow-bellied Slider (Trachemys scripta scripta) from North Carolina, USA

Journal of Wildlife Diseases, 54(2), 371–374.

By: J. Jarred n, G. Lewbart n, K. Stover n, B. Thomas n, R. Maggi n & E. Breitschwerdt n

author keywords: Chelonian; hemoplasma; hemotropic mycoplasma; PCR; wildlife
MeSH headings : Animals; Mycoplasma / classification; Mycoplasma / genetics; Mycoplasma / isolation & purification; Mycoplasma Infections / epidemiology; Mycoplasma Infections / microbiology; Mycoplasma Infections / veterinary; North Carolina / epidemiology; Phylogeny; Turtles / microbiology
TL;DR: Based upon sequencing of the 16S rRNA subunit, one eastern box turtle and one yellow-bellied slider were infected with Mycoplasma spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2018 journal article

Improvement of Bartonella henselae DNA Detection in Cat Blood Samples by Combining Molecular and Culture Methods

Journal of Clinical Microbiology, 56(5).

By: M. Drummond*, B. Lania*, P. Diniz*, R. Gilioli*, D. Demolin*, D. Scorpio*, E. Breitschwerdt n, P. Velho*

Ed(s): B. Fenwick

author keywords: bacteremia; Bartonella; cats; diagnosis; PCR
MeSH headings : Animals; Bacteremia / diagnosis; Bacteremia / microbiology; Bacteremia / veterinary; Bacterial Proteins / genetics; Bartonella Infections / blood; Bartonella Infections / diagnosis; Bartonella Infections / veterinary; Bartonella henselae / genetics; Blood Culture; Cat Diseases / blood; Cat Diseases / diagnosis; Cats; Cytoskeletal Proteins / genetics; DNA, Bacterial / blood; DNA, Bacterial / genetics; Molecular Diagnostic Techniques; Polymerase Chain Reaction; Sensitivity and Specificity; Sequence Analysis, DNA
TL;DR: The frequency of bloodstream infection in 112 cats in southeastern Brazil is determined by comparing and combining the results of multiple conventional and nested PCRs from blood and liquid culture samples, indicating that PCR testing of more than one type of sample provides better sensitivity than a standalone PCR. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2018 journal article

Molecular and Serological Prevalence of Anaplasma phagocytophilum, A. platys, Ehrlichia canis, E. chaffeenses, E. ewingii, Borrelia burgdorferi, Babesia canis, B. gibsoni and B. vogeli among Clinically Healthy Outdoor Dogs in Serbia

Veterinary Parasitology: Regional Studies and Reports, 14, 117–122.

author keywords: Molecular prevalence; seroprevalence; Tick-borne pathogens; Dogs; Serbia
MeSH headings : Anaplasma phagocytophilum / genetics; Anaplasmosis / epidemiology; Animals; Animals, Wild; Antibodies, Bacterial / blood; Babesia / genetics; Borrelia burgdorferi / genetics; Disease Reservoirs / microbiology; Disease Reservoirs / parasitology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs / microbiology; Dogs / parasitology; Ehrlichia canis / genetics; Ehrlichiosis / veterinary; Female; Lyme Disease / veterinary; Male; Polymerase Chain Reaction; Prevalence; Serbia / epidemiology; Seroepidemiologic Studies; Tick-Borne Diseases / epidemiology
TL;DR: It is concluded that outdoor dogs in this territory are reservoirs for B. canis and B. gibsoni and are frequently co-exposed to combinations of Anaplasma and Babesia spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Crossref, NC State University Libraries, ORCID
Added: September 11, 2019

2018 journal article

Molecular surveillance of novel tick-borne organisms in Madagascar's lemurs

TICKS AND TICK-BORNE DISEASES, 9(3), 672–677.

By: B. Qurollo n, P. Larsen*, H. Rakotondrainibe, K. Mahefarisoa*, T. Rajaonarivelo, J. Razafindramanana, E. Breitschwerdt n, R. Junge*, C. Williams*

author keywords: Babesia; Borrelia; Neoehrlichia; Lemurs; Madagascar; One health
MeSH headings : Animals; Babesia / genetics; Babesia / isolation & purification; Babesia / pathogenicity; Babesiosis / epidemiology; Babesiosis / parasitology; Borrelia / genetics; Borrelia / isolation & purification; Borrelia / pathogenicity; Humans; Ixodes / microbiology; Lemur / microbiology; Lemur / parasitology; Lyme Disease / epidemiology; Lyme Disease / microbiology; Lyme Disease / veterinary; Madagascar / epidemiology; One Health; Tick-Borne Diseases / epidemiology; Tick-Borne Diseases / microbiology; Tick-Borne Diseases / parasitology; Tick-Borne Diseases / veterinary; Zoonoses / epidemiology; Zoonoses / microbiology; Zoonoses / parasitology
TL;DR: This study lends support to the One Health concept by highlighting the prevalence of three blood-borne organisms in wild lemurs living in close proximity to domesticated species and humans in Madagascar. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2018 journal article

Pasteurella canis infective endocarditis in a dog

Veterinary Microbiology, 229, 14–19.

By: Z. Kern n, O. Swartley n, P. Neupane n, N. Balakrishnan n & E. Breitschwerdt n

author keywords: Pasteurella cards; Infective vegetative endocarditis; Sepsis; Vasculitis; 16S rDNA PCR; MAIDLTOF
MeSH headings : Animals; Dog Diseases / microbiology; Dogs; Endocarditis, Bacterial / microbiology; Fatal Outcome; Male; Pasteurella / classification; Pasteurella Infections / microbiology; Pasteurella Infections / veterinary
TL;DR: The goal of this study is to detail the clinical presentation and microbiological findings associated with a novel causative agent of infective endocarditis in the dog. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: February 18, 2019

2018 journal article

Potentially Same Novel Ehrlichia Species in Horses in Nicaragua and Brazil

Emerging Infectious Diseases, 24(5), 953–953.

MeSH headings : Animals; Brazil / epidemiology; Ehrlichia / classification; Ehrlichiosis / epidemiology; Ehrlichiosis / parasitology; Ehrlichiosis / veterinary; Horse Diseases / epidemiology; Horse Diseases / parasitology; Horses; Nicaragua / epidemiology
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2018 journal article

Regional prevalences of Borrelia burgdorferi, Borrelia bissettiae, and Bartonella henselae in Ixodes affinis, Ixodes pacificus and Ixodes scapularis in the USA

Ticks and Tick-Borne Diseases, 10(2), 360–364.

By: R. Maggi n, M. Toliver*, T. Richardson n, T. Mather* & E. Breitschwerdt n

author keywords: Borrelia; B. bissettiae; Bartonella; Ixodes; I.affinis; I. scapularis
MeSH headings : Angiomatosis, Bacillary / epidemiology; Animals; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Borrelia / genetics; Borrelia / isolation & purification; Borrelia burgdorferi / genetics; Borrelia burgdorferi / isolation & purification; Coinfection / epidemiology; Coinfection / microbiology; DNA, Bacterial / genetics; Ixodes / microbiology; Lyme Disease / epidemiology; Minnesota / epidemiology; North Carolina / epidemiology; Polymerase Chain Reaction; Prevalence; Sequence Analysis, DNA; United States / epidemiology
TL;DR: Improved understanding of the enzootic cycle, transmission dynamics, and vector competence of Ixodes species (especially I. affinis) for transmission of Borrelia spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: February 4, 2019

2018 journal article

Rheumatological presentation of Bartonella koehlerae and Bartonella henselae bacteremias

Medicine, 97(17), e0465.

By: B. Mozayeni n, R. Maggi n, J. Bradley n & E. Breitschwerdt n

author keywords: Bartonella henselae; Bartonella koehlerae; bartonellosis; breast cyst; EDS Ehlers-Danlos; joint laxity; serology
MeSH headings : Adult; Anti-Bacterial Agents / therapeutic use; Antibodies, Bacterial / blood; Bacteremia / diagnosis; Bacteremia / drug therapy; Bacteremia / physiopathology; Bartonella Infections / diagnosis; Bartonella Infections / drug therapy; Bartonella Infections / physiopathology; Diagnosis, Differential; Ehlers-Danlos Syndrome / diagnosis; Ehlers-Danlos Syndrome / physiopathology; Female; Humans; Polymerase Chain Reaction; Rheumatic Diseases / diagnosis; Rheumatic Diseases / physiopathology; Sequence Analysis, DNA
TL;DR: To facilitate early and directed medical interventions, systemic bartonellosis should potentially be considered as a differential diagnosis in patients with incalcitrant rheumatological symptoms and frequent arthropod exposures or extensive animal contact. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2018 journal article

Using co-occurrence information and trait composition to understand individual plant performance in grassland communities

Scientific Reports, 8(1).

MeSH headings : Algorithms; Biomass; Ecosystem; Grassland; Models, Theoretical; Plant Leaves / growth & development; Plants / classification; Plants / metabolism; Seasons; Species Specificity
TL;DR: The two-year field experiment investigated the relative growth rates of 130 species that had been transplanted into German grassland communities varying in intensities of land-use, demonstrating a limited temporal validity of performance models. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 8, 2019

2017 journal article

Antimicrobial use Guidelines for Treatment of Respiratory Tract Disease in Dogs and Cats: Antimicrobial Guidelines Working Group of the International Society for Companion Animal Infectious Diseases

Journal of Veterinary Internal Medicine, 31(2), 279–294.

By: M. Lappin*, J. Blondeau, D. Boothe*, E. Breitschwerdt n, L. Guardabassi*, D. Lloyd*, M. Papich n, S. Rankin* ...

author keywords: Bronchitis; Pneumonia; Pyothorax; Rhinitis
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Bacterial Infections / drug therapy; Bacterial Infections / veterinary; Cat Diseases / drug therapy; Cats; Dog Diseases / drug therapy; Dogs; Respiratory Tract Diseases / drug therapy; Respiratory Tract Diseases / veterinary
TL;DR: The International Society for Companion Animal Infectious Diseases convened a Working Group of clinical microbiologists, pharmacologists, and internists to share experiences, examine scientific data, review clinical trials, and develop these guidelines to assist veterinarians in making antimicrobial treatment choices. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Bartonella Seroepidemiology in Dogs from North America, 2008-2014

Journal of Veterinary Internal Medicine, 32(1), 222–231.

By: E. Lashnits n, M. Correa n, B. Hegarty n, A. Birkenheuer n & E. Breitschwerdt n

author keywords: Canine; Seroreactivity; Zoonoses
MeSH headings : Animals; Bartonella; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Female; Fluorescent Antibody Technique, Indirect / veterinary; Male; North America / epidemiology; Seroepidemiologic Studies; Spatio-Temporal Analysis
TL;DR: Male intact dogs, mixed breed dogs, and dogs exposed to other CVBD have higher seroreactivity to multiple Bartonella species, and geographic patterns supported broad distribution of exposure, and co‐exposure with otherCVBD was common. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Bartonella henselae in canine cavitary effusions: prevalence, identification, and clinical associations

Veterinary Clinical Pathology, 46(2), 326–330.

By: A. Weeden*, N. Cherry*, E. Breitschwerdt n, A. Cheves* & H. Wamsley*

author keywords: Bartonellosis; dog; peritoneal effusion; pleural effusion; seasonal variation
MeSH headings : Angiomatosis, Bacillary / diagnosis; Angiomatosis, Bacillary / epidemiology; Angiomatosis, Bacillary / pathology; Angiomatosis, Bacillary / veterinary; Animals; Ascitic Fluid / microbiology; Bartonella henselae; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Female; Male; Pericardial Effusion / etiology; Pericardial Effusion / microbiology; Pericardial Effusion / veterinary; Pleural Effusion / etiology; Pleural Effusion / microbiology; Pleural Effusion / veterinary; Prevalence; Seasons
TL;DR: Viable B henselae organisms occur in pleural and peritoneal effusions of dogs; the clinical relevance of which remains unclear and may represent opportunistic infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Bartonellosis, One Health and all creatures great and small

Veterinary Dermatology, 28(1), 96–e21.

By: E. Breitschwerdt n

MeSH headings : Animals; Bartonella; Bartonella Infections / diagnosis; Bartonella Infections / etiology; Bartonella Infections / therapy; Bartonella Infections / veterinary; Communicable Diseases, Emerging / diagnosis; Communicable Diseases, Emerging / therapy; Communicable Diseases, Emerging / veterinary; Humans; Zoonoses / diagnosis; Zoonoses / microbiology; Zoonoses / therapy; Zoonoses / transmission
TL;DR: This review serves as an update on comparative medical aspects of this disease, including the epidemiology, pathogenesis, clinical diagnosis, treatment and challenges, and concludes that directed Bartonella research could substantially reduce a spectrum of chronic and debilitating animal and human diseases, and thereby reduce suffering throughout the world. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Death of Military Working Dogs Due to Bartonella vinsonii Subspecies berkhoffii Genotype III Endocarditis and Myocarditis

MILITARY MEDICINE, 182(3-4), E1864–E1869.

By: L. Shelnutt n, N. Balakrishnan n, J. DeVanna, K. Batey* & E. Breitschwerdt n

MeSH headings : Animals; Bartonellaceae / pathogenicity; Bartonellaceae Infections / complications; Bartonellaceae Infections / diagnosis; Bartonellaceae Infections / veterinary; Dog Diseases / diagnosis; Dogs; Endocarditis / etiology; Endocarditis / veterinary; Female; Male; Military Personnel; Myocarditis / etiology; Myocarditis / veterinary
TL;DR: Comprehensive periodic screening for canine vector-borne infections, in particular occult infections caused by Bartonella spp, is prudent to avoid serious or life-threating illnesses. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2017 journal article

Doxycycline treatment efficacy in dogs with naturally occurring Anaplasma phagocytophilum infection

Journal of Small Animal Practice, 59(5), 286–293.

By: C. Yancey n, P. Diniz*, E. Breitschwerdt n, B. Hegarty n, C. Wiesen* & B. Qurollo n

MeSH headings : Anaplasma phagocytophilum / drug effects; Anaplasma phagocytophilum / genetics; Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / therapeutic use; DNA, Bacterial / blood; DNA, Bacterial / isolation & purification; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dogs; Doxycycline / administration & dosage; Doxycycline / therapeutic use; Ehrlichiosis / veterinary; Lymph Nodes / microbiology; Polymerase Chain Reaction / veterinary; United States
TL;DR: The results of this study support the efficacy of doxycycline therapy for clinical treatment of dogs naturally infected with A. phagocytophilum in the USA. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Improved molecular detection of Babesia infections in animals using a novel quantitative real-time PCR diagnostic assay targeting mitochondrial DNA

Parasites & Vectors, 10(1).

By: B. Qurollo n, N. Archer n, M. Schreeg n, H. Marr n, A. Birkenheuer n, K. Haney n, B. Thomas n, E. Breitschwerdt n

author keywords: Canine babesiosis; Babesia; Mitochondrial DNA; Quantitative PCR
MeSH headings : Animals; Babesia / classification; Babesiosis / diagnosis; Babesiosis / parasitology; DNA, Mitochondrial / genetics; DNA, Protozoan / genetics; Real-Time Polymerase Chain Reaction / methods; Real-Time Polymerase Chain Reaction / veterinary
TL;DR: A more sensitive qPCR assay with a more expansive range of Babesia spp. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Nasogastric tube-administered alectinib achieved long-term survival in a crizotinib-refractory nonsmall cell lung cancer patient with a poor performance status

Clinical Case Reports, 5(6), 931–935.

By: D. Kaufman, A. Kogelnik, R. Mozayeni, N. Cherry & E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Neurological and immunological dysfunction in two patients with Bartonella henselae bacteremia

Clinical Case Reports, 5(6), 931–935.

By: D. Kaufman*, A. Kogelnik*, R. Mozayeni*, N. Cherry* & E. Breitschwerdt n

author keywords: Bartonella; immune dysfunction; Infection; neurological symptoms; vectorborne
TL;DR: Neurobartonellosis should be among the differential diagnoses for patients with persistent or recurrent neurological symptoms of undetermined etiology and microbiological and immunological testing should be concurrently pursued to determine whether defective immune function accompanies Bartonella bacteremia. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Prevalence of Bartonella spp. by culture, PCR and serology, in veterinary personnel from Spain

Parasites & Vectors, 10(1).

author keywords: Bartonella alphaproteobacteria growth medium; Bartonella henselae; Bartonella quintana; Bartonella vinsonii berkhoffii; Bartonella koehlerae; Veterinary personnel; Spain
MeSH headings : Animal Technicians; Animals; Antibodies, Bacterial / blood; Bartonella / genetics; Bartonella / immunology; Bartonella / isolation & purification; Bartonella / physiology; Bartonella Infections / diagnosis; Bartonella Infections / epidemiology; Bartonella Infections / microbiology; Bartonella Infections / transmission; Bartonella henselae / genetics; Bartonella henselae / growth & development; Bartonella henselae / immunology; Bartonella henselae / physiology; Cross-Sectional Studies; DNA, Bacterial / genetics; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Female; Fluorescent Antibody Technique; Genotype; Humans; Male; Prevalence; Real-Time Polymerase Chain Reaction; Sequence Analysis, DNA; Seroepidemiologic Studies; Spain / epidemiology; Surveys and Questionnaires; Veterinarians; Zoonoses
TL;DR: High serological and molecular prevalences of exposure to, or infection with, Bartonella spp. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Prevalence of Vector-Borne Pathogens in Southern California Dogs With Clinical and Laboratory Abnormalities Consistent With Immune-Mediated Disease

Journal of Veterinary Internal Medicine, 31(4), 1081–1090.

By: L. Kidd*, B. Qurollo n, M. Lappin*, K. Richter*, J. Hart*, S. Hill*, C. Osmond*, E. Breitschwerdt n

author keywords: Anaplasmosis; Babesiosis; Ehrlichiosis; Flea; Immune-mediated; Rickettsioses; Tick
MeSH headings : Animals; Babesia; Babesiosis / diagnosis; Babesiosis / epidemiology; Babesiosis / immunology; California / epidemiology; Disease Vectors; Dog Diseases / diagnosis; Dog Diseases / epidemiology; Dog Diseases / immunology; Dogs; Ehrlichia; Ehrlichiosis / diagnosis; Ehrlichiosis / epidemiology; Ehrlichiosis / immunology; Ehrlichiosis / veterinary; Female; Male; Prevalence; Real-Time Polymerase Chain Reaction / veterinary
TL;DR: Repeated testing using serology and PCR enhances detection of infection by vector‐borne pathogens in dogs with clinical signs of immune‐mediated disease. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Sensitivity and specificity levels of two rapid assays for antibodies to Anaplasma spp. in dogs

Journal of Veterinary Diagnostic Investigation, 30(2), 290–293.

By: J. Liu n, M. Eberts n, H. Bewsey n, T. O’Connor n, R. Chandrashekar n & E. Breitschwerdt n

author keywords: Anaplasma phagocytophilum; dogs; tick-borne diseases
MeSH headings : Anaplasma / immunology; Anaplasma phagocytophilum / immunology; Anaplasmosis / blood; Anaplasmosis / epidemiology; Anaplasmosis / microbiology; Animals; Antibodies, Bacterial / blood; Dog Diseases / blood; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dogs; Enzyme-Linked Immunosorbent Assay / methods; Enzyme-Linked Immunosorbent Assay / veterinary; Female; Fluorescent Antibody Technique, Indirect / methods; Fluorescent Antibody Technique, Indirect / veterinary; Male; Reagent Kits, Diagnostic / veterinary; Sensitivity and Specificity; Tick-Borne Diseases / epidemiology; Tick-Borne Diseases / veterinary; United States / epidemiology
TL;DR: The SNAP 4Dx Plus test and the VetScan Canine Anaplasmosis Rapid test are commercial in-house rapid tests for the detection of antibody to these 2 antigenically related Anaplasma species and demonstrate significantly higher sensitivity and specificity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Seroprevalence and risk factors associated with Ehrlichia canis, Anaplasma spp., Borrelia burgdorferi sensu lato, and D. immitis in hunting dogs from southern Italy

Parasitology Research, 116(10), 2651–2660.

By: D. Piantedosi*, B. Neola*, N. D’Alessio*, F. Di Prisco*, M. Santoro*, L. Pacifico*, G. Sgroi*, L. Auletta* ...

author keywords: Ehrlichia canis; Anaplasma spp; Borrelia burgdorferi; Dirofilaria immitis; Hunting dogs; Italy
MeSH headings : Anaplasma; Anaplasmosis / epidemiology; Animals; Borrelia burgdorferi; Dirofilaria immitis; Dirofilariasis / epidemiology; Disease Vectors; Dog Diseases / epidemiology; Dog Diseases / etiology; Dogs; Ehrlichia canis; Ehrlichiosis / epidemiology; Ehrlichiosis / etiology; Ehrlichiosis / veterinary; Enzyme-Linked Immunosorbent Assay; Female; Italy / epidemiology; Lyme Disease / epidemiology; Lyme Disease / veterinary; Male; Risk Factors; Seroepidemiologic Studies
TL;DR: The results of the present survey indicated that hunting dog populations are at relative risk of CVBDs in southern Italy and the historical presence of tick infestation was identified as a risk factor for positivity to E. canis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Seroprevalence of Bartonella species, Coxiella burnetii and Toxoplasma gondii among patients with hematological malignancies: A pilot study in Romania

Zoonoses and Public Health, 64(6), 485–490.

author keywords: Bartonella; Coxiella burnetii; immunocompromised patients; livestock; seroprevalence; Toxoplasma; zoonoses
MeSH headings : Adult; Animals; Bartonella / isolation & purification; Bartonella Infections / complications; Bartonella Infections / epidemiology; Coxiella / isolation & purification; Female; Humans; Leukemia / complications; Leukemia / epidemiology; Male; Middle Aged; Q Fever / complications; Q Fever / epidemiology; Risk Factors; Romania / epidemiology; Seroepidemiologic Studies; Toxoplasma / isolation & purification; Toxoplasmosis / complications; Toxoplasmosis / epidemiology; Zoonoses
TL;DR: Patients receiving immunosuppressive cancer treatments in settings where there is a high degree of human–animal interaction may be at increased risk for opportunistic zoonotic infections or reactivation of latent infections, particularly with respect to Bartonella species. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2017 journal article

Vector-borne and zoonotic diseases of dogs in North-west New South Wales and the Northern Territory, Australia

BMC Veterinary Research, 13(1).

By: A. Shapiro*, G. Brown*, J. Norris*, K. Bosward*, D. Marriot*, N. Balakrishnan n, E. Breitschwerdt n, R. Malik*

author keywords: Dog; Babesia spp.; Anaplasma spp.; Haemotropic mycoplasmas; Coxiella burnetii; Bartonella spp.; Brucella spp.
MeSH headings : Anaplasma / isolation & purification; Anemia / veterinary; Animals; Babesia / isolation & purification; Coxiella burnetii / isolation & purification; DNA, Bacterial; DNA, Protozoan; Dog Diseases / epidemiology; Dog Diseases / microbiology; Dog Diseases / parasitology; Dogs; Humans; Mycoplasma / isolation & purification; New South Wales / epidemiology; Northern Territory / epidemiology; Protozoan Infections, Animal / epidemiology; Real-Time Polymerase Chain Reaction; Thrombocytopenia / veterinary; Zoonoses / epidemiology; Zoonoses / microbiology; Zoonoses / parasitology
TL;DR: Vector-borne pathogens occur in dogs free ranging near Aboriginal communities, with higher detection rates in NT than N-W NSW, and work needs to be extended to tropical coastal communities where fleas are present as well as ticks. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Bartonella henselae, Bartonella koehlerae and Rickettsia rickettsii seroconversion and seroreversion in a dog with acute-onset fever, lameness, and lymphadenopathy followed by a protracted disease course

Veterinary Parasitology: Regional Studies and Reports, 7, 19–24.

By: E. Golly n, E. Breitschwerdt n, N. Balakrishnan n, D. Moore* & P. Bizikova n

TL;DR: Following recent tick exposure in Arkansas, a 2-year-old, female spayed Labradoodle was examined because of a one-week history of lethargy and shifting-leg lameness, and therapeutic elimination of all three pathogens was seemingly achieved. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 11, 2019

2016 journal article

Culture, PCR, DNA sequencing, and second harmonic generation (SHG) visualization of Bartonella henselae from a surgically excised human femoral head

Clinical Rheumatology, 36(7), 1669–1675.

By: M. Ericson*, N. Balakrishnan n, B. Mozayeni, C. Woods*, J. Dencklau*, S. Kelly, E. Breitschwerdt n

MeSH headings : Bartonella henselae / isolation & purification; Cat-Scratch Disease / complications; Cat-Scratch Disease / diagnosis; Female; Humans; Middle Aged; Osteoarthritis, Hip / microbiology; Second Harmonic Generation Microscopy
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Infective endocarditis in 13 cats

Journal of Veterinary Cardiology, 18(3), 213–225.

By: J. Palerme*, A. Jones*, J. Ward*, N. Balakrishnan n, K. Linder n, E. Breitschwerdt n, B. Keene n

author keywords: BAPGM; Bartonella; Duke criteria; Vegetative lesion
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cat Diseases / physiopathology; Cats; Endocarditis, Bacterial / diagnosis; Endocarditis, Bacterial / drug therapy; Endocarditis, Bacterial / physiopathology; Endocarditis, Bacterial / veterinary; Female; Male; Prognosis; Retrospective Studies; Treatment Outcome
TL;DR: In contrast to dogs, cats with IE typically present with clinical signs consistent with cardiac decompensation and locomotor abnormalities suggestive of either thromboembolic disease or inflammatory arthritis, and prognosis is grave. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Pyogranulomatous Pancarditis with Intramyocardial Bartonella henselae San Antonio 2 (BhSA2) in a Dog

Journal of Veterinary Internal Medicine, 31(1), 142–148.

By: T. Donovan*, P. Fox*, N. Balakrishnan n, M. Ericson*, V. Hooker* & E. Breitschwerdt n

author keywords: Canine; Myocarditis; Nephritis; Stealth; Vasculitis
MeSH headings : Animals; Bartonella Infections / microbiology; Bartonella Infections / pathology; Bartonella Infections / veterinary; Bartonella henselae / isolation & purification; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Endocarditis, Bacterial / veterinary; Female; Myocarditis / microbiology; Myocarditis / veterinary; Pericarditis / veterinary
TL;DR: A 6-year-old, female, spayed American Pitbull terrier was presented for progressive lethargy, weakness, and anorexia of 3-weeks duration, and found to have metabolic acidosis and Lyme quantitative C6 ELISA was negative. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Risk Factors for Bartonella species Infection in Blood Donors from Southeast Brazil

PLOS Neglected Tropical Diseases, 10(3), e0004509.

By: P. Diniz*, P. Velho*, L. Pitassi*, M. Drummond*, B. Lania*, M. Barjas-Castro*, S. Sowy*, E. Breitschwerdt n, D. Scorpio*

Ed(s): C. Budke

MeSH headings : Animals; Bacteremia; Bartonella / isolation & purification; Bartonella Infections / epidemiology; Bartonella Infections / parasitology; Blood Donors / statistics & numerical data; Brazil / epidemiology; Cats; Cross-Sectional Studies; Female; Humans; Male; Occupational Exposure; Risk Factors; Zoonoses
TL;DR: These risk factors should be considered during donor screening, as bacteremia by these Bartonella species may not be detected by traditional laboratory screening methods, and it may be transmitted by blood transfusion. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Sarolaner—a novel isoxazoline—addresses the need for enhanced flea and tick control

Veterinary Parasitology, 222, 1–2.

By: E. Breitschwerdt*, S. Little & D. Rugg

MeSH headings : Animals; Ectoparasitic Infestations / prevention & control; Ectoparasitic Infestations / therapy; Ectoparasitic Infestations / veterinary; Isoxazoles / administration & dosage; Siphonaptera; Tick Control / standards; Ticks
Sources: Crossref, NC State University Libraries
Added: September 8, 2019

2016 journal article

Successful treatment of mitral valve endocarditis in a dog associated with 'Actinomyces canis-like' infection

JOURNAL OF VETERINARY CARDIOLOGY, 18(3), 271–277.

By: N. Balakrishnan n, K. Alexander n, B. Keene n, S. Kolluru n, M. Fauls n, I. Rawdon n, E. Breitschwerdt n

author keywords: Bacterial endocarditis; Blood culture; 16s rDNA PCR; Actinomycosis
MeSH headings : Actinomyces; Actinomycosis / veterinary; Animals; Dog Diseases / microbiology; Dogs; Echocardiography / veterinary; Endocarditis / microbiology; Endocarditis / veterinary; Heart Valve Diseases / microbiology; Heart Valve Diseases / veterinary; Male; Mitral Valve
TL;DR: A case of mitral valve endocarditis in a 9-year-old male-castrated Weimaraner caused by an Actinomyces canis-like bacterium, not previously reported in association with infection in dogs is reported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2016 journal article

Vasculitis, cerebral infarction and persistent Bartonella henselae infection in a child

Parasites & Vectors, 9(1).

By: N. Balakrishnan n, M. Ericson*, R. Maggi n & E. Breitschwerdt n

author keywords: Neurobartonellosis; Bartonella henselae San Antonio 2 vasculitis
MeSH headings : Bacteremia; Bartonella Infections / complications; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Bartonella henselae / genetics; Bartonella henselae / immunology; Bartonella henselae / isolation & purification; Brain / microbiology; Brain / pathology; Canada; Cerebral Infarction / diagnosis; Cerebral Infarction / etiology; Child; Female; Humans; Sequence Analysis, DNA; Vasculitis / complications; Vasculitis / diagnosis; Vasculitis / microbiology
TL;DR: B. henselae bacteremia, potentially spanning a 12-year time frame, in conjunction with the therapeutic administration of immunosuppressive drugs may have resulted in a progression and potentiation of the neurological disease that was partially reversible following antibiotic administration. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2016 journal article

Vertical transmission of Anaplasma platys and Leishmania infantum in dogs during the first half of gestation

Parasites & Vectors, 9(1).

By: M. Latrofa*, F. Dantas-Torres*, D. de Caprariis*, C. Cantacessi*, G. Capelli*, R. Lia, E. Breitschwerdt n, D. Otranto*

author keywords: Vertical transmission; Leishmania infantum; Anaplasma platys; Dog; Real-time PCR
MeSH headings : Anaplasma / genetics; Anaplasma / isolation & purification; Anaplasma / physiology; Anaplasmosis / parasitology; Anaplasmosis / transmission; Animals; Dog Diseases / microbiology; Dog Diseases / parasitology; Dog Diseases / transmission; Dogs; Female; Infectious Disease Transmission, Vertical / veterinary; Italy; Leishmania infantum / genetics; Leishmania infantum / immunology; Leishmania infantum / isolation & purification; Leishmania infantum / physiology; Leishmaniasis, Visceral / parasitology; Leishmaniasis, Visceral / transmission; Leishmaniasis, Visceral / veterinary; Ovary / microbiology; Ovary / parasitology; Pregnancy; Pregnancy Complications, Infectious / microbiology; Pregnancy Complications, Infectious / parasitology; Pregnancy Complications, Infectious / veterinary; Uterus / microbiology; Uterus / parasitology
TL;DR: Results from this study suggest that, in contrast to L. infantum, A. platys can be transmitted from pregnant dogs to their offspring during the first half of gestation, and this hypothesis remains to be verified, for instance via direct observation of parasites in postpartum foetal tissues. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

A putative marker for human pathogenic strains of Anaplasma phagocytophilum correlates with geography and host, but not human tropism

Ticks and Tick-Borne Diseases, 7(2), 390–393.

By: J. Foley*, N. Stephenson*, M. Cubilla*, B. Qurollo n & E. Breitschwerdt n

author keywords: Dog; Horse; Host-niche polymorphism; Ixodes pacificus; Tick-borne disease
MeSH headings : Anaplasma phagocytophilum / genetics; Anaplasma phagocytophilum / isolation & purification; Animals; Arachnid Vectors / microbiology; Biomarkers / metabolism; Dog Diseases / microbiology; Dogs; Ehrlichiosis / microbiology; Geography; Horse Diseases / microbiology; Horses; Host Specificity; Humans; Ixodes / microbiology; Membrane Proteins / genetics; Membrane Proteins / metabolism; Phylogeny; Sequence Analysis, DNA / veterinary; Tropism
TL;DR: Assessing 117 strains from 14 host species from across the US found thatPhylogenetic clades were associated with geography, but not host species, and a virulent clade that lacks drhm and infects dogs, horses, and humans in northeastern US was identified. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Bartonella henselaeas a cause of acute-onset febrile illness in cats

Journal of Feline Medicine and Surgery Open Reports, 1(2), 205511691560045.

By: E. Breitschwerdt n, J. Broadhurst & N. Cherry*

TL;DR: It is concluded that microbiological diagnosis and treatment of B henselae infection in cats can be challenging, that antibody titration results and resolution of clinical abnormalities may not correlate with a therapeutic cure, and that fever and potentially neutropenia should be differential diagnostic considerations for young cats with suspected bartonellosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: January 24, 2021

2015 journal article

Bartonella spp. Bacteremia in Blood Donors from Campinas, Brazil

PLOS Neglected Tropical Diseases, 9(1), e0003467.

By: L. Pitassi*, P. de Paiva Diniz*, D. Scorpio*, M. Drummond*, B. Lania*, M. Barjas-Castro*, R. Gilioli*, S. Colombo* ...

Ed(s): D. Walker

MeSH headings : Adult; Bacteremia / epidemiology; Bartonella Infections / epidemiology; Bartonella Infections / transmission; Bartonella henselae / genetics; Bartonella henselae / immunology; Bartonella henselae / isolation & purification; Blood Donors; Brazil / epidemiology; Cross-Sectional Studies; Female; Humans; Male; Polymerase Chain Reaction; Sequence Analysis, DNA
TL;DR: Bartonella species are blood-borne, re-emerging organisms, capable of causing prolonged infection with diverse disease manifestations, from asymptomatic bacteremia to chronic debilitating disease and death, and screening of blood supplies for this pathogen is not routinely performed. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Did Bartonella henselae contribute to the deaths of two veterinarians?

Parasites & Vectors, 8(1).

By: E. Breitschwerdt n

author keywords: Infection; Disease; Mortality; Cancer; Heart valve; Blood
MeSH headings : Aged; Animals; Bartonella Infections / etiology; Bartonella Infections / microbiology; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Bartonella henselae / physiology; Cat Diseases / microbiology; Cats; Fatal Outcome; Humans; Male; Middle Aged; Occupational Exposure / analysis; Veterinarians; Zoonoses / microbiology; Zoonoses / transmission
TL;DR: Bartonella henselae may or may not have been responsible for the deaths of two veterinarians, and recent evidence indicates that this genus is of much greater medical importance than is currently appreciated by the majority of the biomedical community. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Erratum to ‘Novel Bartonella infection in northern and southern sea otters (Enhydra lutris kenyoni and Enhydra lutris nereis)’

Erratum to ‘Novel Bartonella infection in northern and southern sea otters (Enhydra lutris kenyoni and Enhydra lutris nereis).’ Veterinary Microbiology, 181(3-4), 336.

By: S. Carrasco*, B. Chomel*, V. Gill*, R. Kasten*, R. Maggi n, E. Breitschwerdt n, B. Byrne*, K. Burek-Huntington ...

UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Infection with Bartonella henselae in a Danish Family

Journal of Clinical Microbiology, 53(5), 1556–1561.

By: R. Maggi n, N. Balakrishnan n, J. Bradley n & E. Breitschwerdt n

Ed(s): B. Fenwick

MeSH headings : Adolescent; Adult; Angiomatosis, Bacillary / diagnosis; Angiomatosis, Bacillary / microbiology; Angiomatosis, Bacillary / transmission; Bartonella henselae / classification; Bartonella henselae / genetics; Bartonella henselae / isolation & purification; Child; Family Health; Female; Genotype; Genotyping Techniques; Humans; Infant; Male; Middle Aged; Polymerase Chain Reaction; Sequence Analysis, DNA
TL;DR: Molecular microbiological evidence of Bartonella henselae genotype San Antonio 2 (SA2) infection in four of six Danish family members, including a child who died of unknown causes at 14 months of age is provided. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Naturally OccurringEhrlichia ewingiiandMycoplasmasp. Co-Infection in a Goat

Journal of Veterinary Internal Medicine, 29(6), 1735–1738.

By: K. Meichner n, B. Qurollo n, K. Anderson n, C. Grindem n, M. Savage n & E. Breitschwerdt n

author keywords: Caprine; Ehrlichiosis; Tick-borne disease
MeSH headings : Animals; Coinfection / microbiology; Coinfection / veterinary; Ehrlichia / isolation & purification; Ehrlichiosis / complications; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Female; Goat Diseases / microbiology; Goats; Mycoplasma / isolation & purification; Mycoplasma Infections / complications; Mycoplasma Infections / microbiology; Mycoplasma Infections / veterinary; Polymerase Chain Reaction; RNA, Bacterial / genetics; RNA, Ribosomal, 16S / genetics
TL;DR: A 9-year-old nonpregnant, nonlactating doe Boer goat was examined because of a 2-day history of not being able to stand and some degree of chronicity was considered likely. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Potentially Novel Ehrlichia Species in Horses, Nicaragua

Emerging Infectious Diseases, 21(2), 335–338.

By: V. O’Nion n, H. Montilla n, B. Qurollo n, R. Maggi n, B. Hegarty n, S. Tornquist n, E. Breitschwerdt n

MeSH headings : Animals; Ehrlichia / classification; Ehrlichia / genetics; Ehrlichiosis / veterinary; Horse Diseases / epidemiology; Horse Diseases / microbiology; Horses; Molecular Typing; Nicaragua / epidemiology; Phylogeny; RNA, Ribosomal, 16S / genetics; Serotyping
TL;DR: Sequencing of 16S rDNA, sodB, and groEL genes indicated that the bacterium is most likely a novel Ehrlichia species and the potential for canine and human infection remain unknown. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Prevalence of Bartonella spp. in Canine Cutaneous Histiocytoma

Journal of Comparative Pathology, 153(1), 14–21.

By: E. Pultorak n, K. Linder n, R. Maggi n, N. Balakrishnan n & E. Breitschwerdt n

author keywords: Bartonella; canine cutaneous histiocytoma; dog
MeSH headings : Animals; Bartonella Infections / complications; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Dog Diseases / microbiology; Dogs; Histiocytoma, Benign Fibrous / microbiology; Histiocytoma, Benign Fibrous / veterinary; Prevalence; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms / microbiology; Skin Neoplasms / veterinary
TL;DR: It is hypothesized that Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Serological and molecular analysis of feline vector-borne anaplasmosis and ehrlichiosis using species-specific peptides and PCR

Parasites & Vectors, 8(1), 320.

By: B. Hegarty n, B. Qurollo n, B. Thomas n, K. Park n, R. Chandrashekar*, M. Beall*, B. Thatcher*, E. Breitschwerdt n

author keywords: Anaplasma; Borrelia; Ehrlichia; Cats; Vector-borne pathogens
MeSH headings : Anaplasma / genetics; Anaplasma / immunology; Anaplasma / isolation & purification; Anaplasmosis / blood; Anaplasmosis / diagnosis; Anaplasmosis / microbiology; Animals; Antibodies, Bacterial / blood; Cat Diseases / blood; Cat Diseases / diagnosis; Cat Diseases / microbiology; Cats; Ehrlichia / genetics; Ehrlichia / immunology; Ehrlichia / isolation & purification; Ehrlichiosis / blood; Ehrlichiosis / diagnosis; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Female; Male; Peptides / genetics; Polymerase Chain Reaction; Prospective Studies; Species Specificity
TL;DR: This study provides the first evidence for E.chaffeensis and E.ewingii infection in naturally-exposed cats in North America and supports the need for regional, serological and molecular FVBP prevalence studies, and the need to further optimize serodiagnostic and PCR testing for cats. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2015 journal article

Splenic vasculitis, thrombosis, and infarction in a febrile dog infected with Bartonella henselae

Journal of Veterinary Emergency and Critical Care, 25(6), 789–794.

By: S. Friedenberg*, N. Balakrishnan n, J. Guillaumin*, E. Cooper*, K. Lewis*, D. Russell*, E. Breitschwerdt n

author keywords: B. henselae; polyarthritis; splenic vasculitis; thrombosis
MeSH headings : Animals; Bartonella Infections / complications; Bartonella Infections / pathology; Bartonella Infections / veterinary; Bartonella henselae / genetics; DNA, Bacterial; Dog Diseases / etiology; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Female; Infarction / etiology; Infarction / veterinary; Spleen / blood supply; Splenic Diseases / microbiology; Splenic Diseases / pathology; Splenic Diseases / veterinary; Thrombosis / veterinary; Vasculitis / pathology; Vasculitis / veterinary
TL;DR: A potential role for this bacterium as a cause of vasculitis and thromboembolism, which have not been previously reported in association with B. henselae infection in dogs, is established. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

A serological survey of tick-borne pathogens in dogs in North America and the Caribbean as assessed by Anaplasma phagocytophilum, A. platys, Ehrlichia canis, E. chaffeensis, E. ewingii, and Borrelia burgdorferi species-specific peptides

Infection Ecology & Epidemiology, 4(1), 24699.

By: B. Qurollo n, R. Chandrashekar*, B. Hegarty n, M. Beall*, B. Stillman*, J. Liu*, B. Thatcher*, E. Pultorak n ...

TL;DR: This study demonstrated significant shifts in canine vector-borne disease seroprevalence rates, and the use of specific peptides facilitated improved geographic delineation of tick-borne pathogen distributions among dogs, which may enhance epidemiological surveillance ofvector-borne pathogens shared by dogs and humans. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 13, 2021

2014 journal article

Anaplasma platys in Bone Marrow Megakaryocytes of Young Dogs

Journal of Clinical Microbiology, 52(6), 2231–2234.

By: A. De Tommasi*, G. Baneth*, E. Breitschwerdt n, D. Stanneck*, F. Dantas-Torres*, D. Otranto*, D. de Caprariis*

MeSH headings : Anaplasma / isolation & purification; Anaplasmosis / microbiology; Anaplasmosis / pathology; Animals; Bone Marrow / microbiology; Dog Diseases / microbiology; Dog Diseases / pathology; Dogs; Female; Male; Megakaryocytes / microbiology
TL;DR: Cellular inclusions were documented in bone marrow thrombocyte precursors of two young naturally infected dogs, indicating that A. platys can infect megakaryocytes and promegakaryocyte. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Bartonella clarridgeiae Bacteremia Detected in an Asymptomatic Blood Donor

Journal of Clinical Microbiology, 53(1), 352–356.

By: G. Vieira-Damiani*, P. Diniz*, L. Pitassi*, S. Sowy*, D. Scorpio*, B. Lania*, M. Drummond*, T. Soares* ...

Ed(s): K. Carroll

MeSH headings : Adult; Bacteriological Techniques / methods; Bartonella / genetics; Bartonella Infections / diagnosis; Bartonella Infections / microbiology; Blood Donors; Humans; Male; Polymerase Chain Reaction; Sequence Analysis, DNA
TL;DR: It is reported for the first time an asymptomatic human blood donor infected with B. clarridgeiae, as documented by enrichment blood culture, PCR, and DNA sequencing. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Bartonella henselae Infections In An Owner and Two Papillon Dogs Exposed to Tropical Rat Mites (Ornithonyssus bacoti)

Vector-Borne and Zoonotic Diseases, 14(10), 703–709.

By: J. Bradley n, P. Mascarelli n, C. Trull n, R. Maggi n & E. Breitschwerdt n

author keywords: Neuropsychiatric symptoms; Mites; Vector; Pruritis; Edema
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Antibodies, Bacterial / blood; Bartonella Infections / drug therapy; Bartonella Infections / microbiology; Bartonella Infections / transmission; Bartonella henselae / genetics; Bartonella henselae / immunology; Bartonella henselae / isolation & purification; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Dog Diseases / drug therapy; Dog Diseases / microbiology; Dog Diseases / transmission; Dogs; Doxycycline / therapeutic use; Female; Humans; Male; Mite Infestations / parasitology; Mites / microbiology; Polymerase Chain Reaction; Pruritus / drug therapy; Pruritus / microbiology; Pruritus / veterinary; Rats; Sequence Analysis, DNA; Zoonoses
TL;DR: Clinicians and vector biologists should consider the possibility that rat mites may play a role in Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Bartonella henselae and B. koehlerae DNA in Birds

Emerging Infectious Diseases, 20(3), 490–492.

By: P. Mascarelli n, M. McQuillan n, C. Harms n, R. Harms n & E. Breitschwerdt n

MeSH headings : Animals; Bartonella / classification; Bartonella / genetics; Bartonella Infections / veterinary; Bartonella henselae / classification; Bartonella henselae / genetics; Bird Diseases / microbiology; Bird Diseases / transmission; Birds; DNA, Bacterial; Disease Reservoirs / microbiology; Humans; Zoonoses / microbiology; Zoonoses / transmission
TL;DR: The substantial mobility, broad distribution, and migrations of birds make them ideal reservoir hosts for dispersal of infectious agents and the possibility that persistent blood-borne infection can occur in nonmammals and that the host range for Bartonella spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 30, 2019

2014 journal article

Bartonellosis: One Health Perspectives for an Emerging Infectious Disease

ILAR Journal, 55(1), 46–58.

By: E. Breitschwerdt n

author keywords: animals; bacteria; Bartonella; bartonellosis; disease; One Health; reservoirs; vectors
MeSH headings : Animals; Arthropod Vectors / microbiology; Bartonella / genetics; Bartonella / pathogenicity; Bartonella Infections / epidemiology; Bartonella Infections / veterinary; Communicable Diseases, Emerging / epidemiology; Communicable Diseases, Emerging / veterinary; Humans; Research / trends; Species Specificity; Zoonoses / epidemiology
TL;DR: A One Health approach to bartonellosis and other zoonotic infections is needed to properly address animal health, public health, and environmental factors that influence the distribution and transmission of these bacteria. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Bilateral mandibular pyogranulomatous lymphadenitis and pulmonary nodules in a dog with Bartonella henselae bacteremia

Canadian Veterinary Journal, 55(10), 970–974.

By: M. Tucker, R. Sellon, R. Tucker, T. Wills, A. Simonsen, R. Maggi, E. Breitschwerdt

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Case Report: Molecular Evidence of Anaplasma platys Infection in Two Women from Venezuela

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 91(6), 1161–1165.

By: C. Arraga-Alvarado n, B. Qurollo n, O. Parra n, M. Berrueta n, B. Hegarty n & E. Breitschwerdt n

MeSH headings : Adult; Anaplasma / genetics; Anaplasmosis / diagnosis; Base Sequence; DNA Primers; DNA, Bacterial / genetics; Female; Humans; Middle Aged; Polymerase Chain Reaction; Venezuela
TL;DR: Two case reports of Anaplasma platys detection in two women from Venezuela are presented, providing further support for A. platys as a zoonotic tick-borne pathogen, most likely of low pathogenicity. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2014 journal article

Co-infection with Anaplasma platys, Bartonella henselae, Bartonella koehlerae and ‘Candidatus Mycoplasma haemominutum’ in a cat diagnosed with splenic plasmacytosis and multiple myeloma

Journal of Feline Medicine and Surgery, 16(8), 713–720.

By: B. Qurollo n, N. Balakrishnan n, C. Cannon n, R. Maggi n & E. Breitschwerdt n

MeSH headings : Animals; Bartonella Infections / veterinary; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cats; Coinfection; Doxycycline / therapeutic use; Multiple Myeloma / diagnosis; Multiple Myeloma / drug therapy; Multiple Myeloma / veterinary; Mycoplasma Infections / drug therapy; Mycoplasma Infections / veterinary; Polymerase Chain Reaction / veterinary
TL;DR: Co-infection with multiple vector-borne pathogens should be a diagnostic consideration in cats with chronic hypergammaglobulinemia, monoclonal gammopathy and splenic plasmacytosis. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Comparison of serological and molecular panels for diagnosis of vector-borne diseases in dogs

Parasites & Vectors, 7(1), 127.

By: R. Maggi n, A. Birkenheuer n, B. Hegarty n, J. Bradley n, M. Levy n & E. Breitschwerdt n

author keywords: Canine vector-borne diseases; Serology; Molecular testing; Diagnostic panel
MeSH headings : Animals; Bacterial Infections / blood; Bacterial Infections / diagnosis; Bacterial Infections / microbiology; Bacterial Infections / veterinary; DNA, Bacterial / genetics; Dog Diseases / blood; Dog Diseases / diagnosis; Dogs; Parasitic Diseases, Animal / blood; Parasitic Diseases, Animal / diagnosis; Parasitic Diseases, Animal / parasitology; Serologic Tests / veterinary
TL;DR: Serological and PCR assays should be used in parallel to maximize CVBD diagnosis, and a panel combining serological and molecular assays run in parallel resulted in a 4-58% increase in the recognition of exposure to or infection with CVBD. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

ConcurrentBartonella henselaeinfection in a dog with panniculitis and owner with ulcerated nodular skin lesions

Veterinary Dermatology, 26(1), 60–e22.

By: M. Rossi, N. Balakrishnan n, K. Linder n, J. Messa* & E. Breitschwerdt n

MeSH headings : Aged; Angiomatosis, Bacillary / diagnosis; Angiomatosis, Bacillary / pathology; Angiomatosis, Bacillary / transmission; Angiomatosis, Bacillary / veterinary; Animals; Bartonella henselae; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dog Diseases / pathology; Dog Diseases / transmission; Dogs; Female; Humans; Male; Skin / pathology; Skin Ulcer / microbiology; Zoonoses / diagnosis; Zoonoses / microbiology; Zoonoses / pathology
TL;DR: B Bartonella henselae is an emerging zoonotic pathogen that induces granulomatous inflammatory lesions in various tissues of animals, including humans, and is concluded that this bacterium had a contributory or causative role in the development of the dermatological lesions in the dog and owner. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Detection of Bartonella Species in the Blood of Veterinarians and Veterinary Technicians: A Newly Recognized Occupational Hazard?

Vector-Borne and Zoonotic Diseases, 14(8), 563–570.

By: P. Lantos*, R. Maggi n, B. Ferguson*, J. Varkey*, L. Park*, E. Breitschwerdt n, C. Woods*

author keywords: Bartonella; Diagnostic test; Veterinarian; Zoonosis; Bacteremia
TL;DR: This study supports an emerging body of evidence that cryptic Bartonella bloodstream infection may be more frequent in humans than previously recognized and may induce symptoms. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Development and Validation of a Sensitive and Specific sodB-Based Quantitative PCR Assay for Molecular Detection of Ehrlichia Species

Journal of Clinical Microbiology, 52(11), 4030–4032.

By: B. Qurollo n, D. Riggins n, A. Comyn n, M. Zewde n & E. Breitschwerdt n

MeSH headings : Animals; Bacterial Proteins / genetics; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Dogs; Ehrlichia / genetics; Ehrlichia / isolation & purification; Ehrlichiosis / diagnosis; Ehrlichiosis / microbiology; Ehrlichiosis / veterinary; Humans; Molecular Sequence Data; RNA, Ribosomal, 16S / genetics; Real-Time Polymerase Chain Reaction / methods; Sensitivity and Specificity; Sequence Analysis, DNA; Superoxide Dismutase / genetics
TL;DR: A sensitive and specific sodB-based quantitative PCR assay to detect Ehrlichia spp. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2014 journal article

Evaluation of blood and bone marrow in selected canine vector-borne diseases

Parasites & Vectors, 7.

By: A. Tommasi*, D. Otranto*, T. Furlanello*, S. Tasca*, C. Cantacessi*, E. Breitschwerdt n, D. Stanneck*, F. Dantas-Torres* ...

Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2014 journal article

Evaluation of blood and bone marrow in selected canine vector-borne diseases

Parasites & Vectors, 7(1), 534.

By: A. De Tommasi*, D. Otranto*, T. Furlanello*, S. Tasca*, C. Cantacessi*, E. Breitschwerdt n, D. Stanneck*, F. Dantas-Torres* ...

author keywords: Bone marrow; Cytology; Vector-borne pathogens; Dysplasia; Secondary dysmyelopoiesis
MeSH headings : Animals; Bacterial Infections / pathology; Bacterial Infections / veterinary; Bone Marrow / pathology; Bone Marrow Cells; Disease Vectors; Dog Diseases / blood; Dog Diseases / parasitology; Dog Diseases / pathology; Dogs; Female; Male; Parasitic Diseases, Animal / pathology
TL;DR: The aim of the present study was to assess the pathological changes in canine BM associated with natural infections by four vector-borne pathogens, as well as to determine the relationships between such changes and abnormalities of the peripheral blood. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 13, 2021

2014 journal article

Experimental infection of cats with Afipia felis and various Bartonella species or subspecies

Veterinary Microbiology, 172(3-4), 505–510.

By: B. Chomel*, R. Kasten*, M. Stuckey*, E. Breitschwerdt n, R. Maggi n, J. Henn*, J. Koehler*, C. Chang*

author keywords: Bartonella; Afipia felis; Cats; Experimental infection; Zoonosis
MeSH headings : Afipia; Animals; Bacteremia / veterinary; Bartonella / classification; Bartonella / genetics; Bartonella Infections / microbiology; Bartonella Infections / veterinary; Cat Diseases / microbiology; Cats; Gram-Negative Bacterial Infections / veterinary; Polymerase Chain Reaction
TL;DR: Most of the cats seroconverted, but only the cats inoculated with B. rochalimae became bacteremic, indicating that cats are not natural hosts of A. felis or the other Bartonella species or subspecies tested in this study. (via Semantic Scholar)