@article{chee_mihalko_nellenbach_sollinger_huang_hon_pandit_cheng_brown_2023, title={Wound‐triggered shape change microgels for the development of enhanced biomimetic function platelet‐like particles}, volume={112}, ISSN={1549-3296 1552-4965}, url={http://dx.doi.org/10.1002/jbm.a.37625}, DOI={10.1002/jbm.a.37625}, abstractNote={Abstract}, number={4}, journal={Journal of Biomedical Materials Research Part A}, publisher={Wiley}, author={Chee, Eunice and Mihalko, Emily and Nellenbach, Kimberly and Sollinger, Jennifer and Huang, Ke and Hon, Mason and Pandit, Sanika and Cheng, Ke and Brown, Ashley}, year={2023}, month={Oct}, pages={613–624} } @article{chee_brown_2020, title={Biomimetic antimicrobial material strategies for combating antibiotic resistant bacteria}, volume={8}, ISSN={2047-4830 2047-4849}, url={http://dx.doi.org/10.1039/C9BM01393H}, DOI={10.1039/c9bm01393h}, abstractNote={Antibiotic drugs have revolutionized the field of medicine for almost 90 years. However, continued use has led to the rise of antibiotic resistant bacteria. To combat these bacteria, biomimetic material strategies have been investigated.}, number={4}, journal={Biomaterials Science}, publisher={Royal Society of Chemistry (RSC)}, author={Chee, Eunice and Brown, Ashley C.}, year={2020}, pages={1089–1100} } @article{im_ko_lee_chee_chee_2020, title={Immigration Transition and Cognitive Symptoms During Menopausal Transition}, volume={42}, ISSN={["1552-8456"]}, DOI={10.1177/0193945919858366}, abstractNote={ Many studies have been conducted to investigate the effect of cultural influences on menopausal symptoms; however, associations between immigration transition and cognitive symptoms have rarely been uncovered. This secondary analysis aimed to determine these associations among 1,054 midlife women in the United States using the data from two national Internet surveys. The surveys included multiple questions on immigration transition, health and menopausal status, and the Cognitive Symptom Index for Midlife Women. The data analysis was performed using descriptive and inferential statistics including hierarchical multiple regression analyses. Nonimmigrants had larger numbers and higher severity scores of total cognitive symptoms than immigrants ( p < .001). Immigration status explained 1.28% of the total variances in the total numbers and 1.46% of the total variances in the total severity scores of total cognitive symptoms ( p < .001). The study supported significant associations between immigration transition and cognitive symptoms of women at midlife. }, number={4}, journal={WESTERN JOURNAL OF NURSING RESEARCH}, author={Im, Eun-Ok and Ko, Young and Lee, Yaelim and Chee, Eunice and Chee, Wonshik}, year={2020}, month={Apr}, pages={269–277} } @article{im_kim_xu_lee_hamajima_inohara_chang_chee_chee_2020, title={Issues in Recruiting and Retaining Asian American Breast Cancer Survivors in a Technology-Based Intervention Study}, volume={43}, ISSN={["1538-9804"]}, DOI={10.1097/NCC.0000000000000657}, abstractNote={ Background Difficulties in recruiting and retaining Asian Americans in traditional research have been well documented. Despite an increasing number of technology-based cancer studies among racial/ethnic minorities, little is still known about potential issues in recruiting and retaining racial/ethnic minority cancer survivors for technology-based intervention research. }, number={1}, journal={CANCER NURSING}, author={Im, Eun-Ok and Kim, Sangmi and Xu, Shu and Lee, Chiyoung and Hamajima, Yuko and Inohara, Ayako and Chang, Kathleen and Chee, Eunice and Chee, Wonshik}, year={2020}, pages={E22–E29} } @article{chee_nandi_nellenbach_mihalko_snider_morrill_bond_sproul_sollinger_cruse_et al._2020, title={Nanosilver composite pNIPAm microgels for the development of antimicrobial platelet‐like particles}, volume={108}, ISSN={1552-4973 1552-4981}, url={http://dx.doi.org/10.1002/jbm.b.34592}, DOI={10.1002/jbm.b.34592}, abstractNote={Abstract}, number={6}, journal={Journal of Biomedical Materials Research Part B: Applied Biomaterials}, publisher={Wiley}, author={Chee, Eunice and Nandi, Seema and Nellenbach, Kimberly and Mihalko, Emily and Snider, Douglas B. and Morrill, Landon and Bond, Andrew and Sproul, Erin and Sollinger, Jennifer and Cruse, Glenn and et al.}, year={2020}, month={Feb}, pages={2599–2609} } @article{im_ji_kim_chee_bao_mao_chee_2019, title={Challenges in a Technology-Based Cancer Pain Management Program Among Asian American Breast Cancer Survivors}, volume={37}, ISSN={["1538-9774"]}, DOI={10.1097/CIN.0000000000000503}, abstractNote={This paper aims to discuss the challenges faced during a pilot study that tested a technology-based cancer pain management program among Asian American survivors of breast cancer and provide directions for future technology-based interventions for racial and ethnic minorities. Data consisting of research diaries and meeting minutes underwent content analysis to extract themes that reflected the challenges. The challenges included those related to (1) diversities within the population of Asian American survivors of breast cancer; (2) survivors' treatment and healing process; (3) Internet resources from the participants' countries of origin; (4) building trust between researchers and participants/gatekeepers; (5) fidelity of the intervention; and (6) cultural sensitivity. Future design and implementation of technology-based programs for racial and ethnic minorities must consider these challenges.}, number={5}, journal={CIN-COMPUTERS INFORMATICS NURSING}, author={Im, Eun-Ok and Ji, Xiaopeng and Kim, Sangmi and Chee, Eunice and Bao, Ting and Mao, Jun J. and Chee, Wonshik}, year={2019}, month={May}, pages={243–249} } @article{im_kim_lee_chee_mao_chee_2019, title={Decreasing menopausal symptoms of Asian American breast cancer survivors through a technology-based information and coaching/support program}, volume={26}, ISSN={["1530-0374"]}, DOI={10.1097/GME.0000000000001249}, abstractNote={Abstract}, number={4}, journal={MENOPAUSE-THE JOURNAL OF THE NORTH AMERICAN MENOPAUSE SOCIETY}, author={Im, Eun-Ok and Kim, Sangmi and Lee, Chiyoung and Chee, Eunice and Mao, Jun J. and Chee, Wonshik}, year={2019}, month={Apr}, pages={373–382} } @article{sproul_nandi_chee_sivadanam_igo_schreck_brown_2019, title={Development of Biomimetic Antimicrobial Platelet-Like Particles Comprised of Microgel Nanogold Composites}, volume={6}, ISSN={2364-4133 2364-4141}, url={http://dx.doi.org/10.1007/s40883-019-00121-6}, DOI={10.1007/s40883-019-00121-6}, abstractNote={A blood clot is formed in response to bleeding by platelet aggregation and adherence to fibrin fibers. Platelets contract over time, stabilizing the clot, which contributes to wound healing. We have developed platelet-like particles (PLPs) that augment clotting and induce clot retraction by mimicking the fibrin-binding capabilities and morphology of native platelets. Wound repair following hemostasis can be complicated by infection; therefore, we aim to augment wound healing by combining PLPs with antimicrobial gold to develop nanogold composites (NGCs). PLPs were synthesized with N-isopropylacrylamide (NIPAm)/co-acrylic acid in a precipitation polymerization reaction and conjugated to a fibrin-specific antibody. Two methods were employed to create NGCs: (1) noncovalent swelling with aqueous gold nanospheres, and (2) covalent seeding and growth. Since the ability of PLPs to mimic platelet morphology and clot retraction requires a high degree of particle deformability, we investigated how PLPs created from NGCs affected these properties. Cryogenic scanning electron microscopy (cryoSEM) and atomic force microscopy (AFM) demonstrated that particle deformability, platelet-mimetic morphology, and clot retraction were maintained in NGC-based PLPs. The effect of NGCs on bacterial adhesion and growth was assessed with antimicrobial assays. These results demonstrate NGCs fabricated through noncovalent and covalent methods retain deformability necessary for clot collapse and exhibit some antimicrobial potential. Therefore, NGCs are promising materials for preventing hemorrhage and infection following trauma. Following injury, a blood clot is formed by platelets aggregating and binding to fibrin fibers. Platelets contract over time, stabilizing the clot, which contributes to wound healing. We have developed PLPs that enhance clotting and stimulate clot retraction by mimicking the fibrin-binding capabilities and morphology of native platelets. Wound repair following hemostasis can be complicated by infection; therefore, we aim to amplify wound healing by combining PLPs with antimicrobial gold to develop NGCs. These NGC PLPs mimic platelet morphology, generate clot retraction, demonstrate some antimicrobial potential, and are promising materials for preventing blood loss and infection following trauma. Future work will include exploring the application of these particles to treat hemorrhage and infection following traumatic injury.}, number={3}, journal={Regenerative Engineering and Translational Medicine}, publisher={Springer Science and Business Media LLC}, author={Sproul, Erin P. and Nandi, Seema and Chee, Eunice and Sivadanam, Supriya and Igo, Benjamin J. and Schreck, Luisa and Brown, Ashley C.}, year={2019}, month={Aug}, pages={299–309} } @article{im_hu_cheng_ko_chee_chee_2019, title={Racial/Ethnic Differences in Cognitive Symptoms During the Menopausal Transition}, volume={41}, ISSN={["1552-8456"]}, DOI={10.1177/0193945918767660}, abstractNote={ The purpose of this study was to explore racial/ethnic differences in midlife women’s cognitive symptoms among four major racial/ethnic groups in the United States and to determine multiple factors that influenced the women’s cognitive symptoms. This was a secondary analysis of the data from two larger studies among 1,054 midlife women. The instruments included multiple questions on background characteristics and health and menopausal status, and the Cognitive Symptom Index for Midlife Women. The data were analyzed using multiple logistic and Poisson regression analyses. There existed significant racial/ethnic differences in the total numbers and total severity scores of cognitive symptoms ( p < .01); non-Hispanic Asians had significantly lower total numbers and total severity scores compared with other racial/ethnic groups. Socioeconomic status and health and menopausal status were significant factors that influenced cognitive symptoms across racial/ethnic groups ( p < .05). Further studies on racial/ethnic differences in cognitive symptoms are needed with diverse groups of midlife women. }, number={2}, journal={WESTERN JOURNAL OF NURSING RESEARCH}, author={Im, Eun-Ok and Hu, Yun and Cheng, Ching-Yu and Ko, Young and Chee, Eunice and Chee, Wonshik}, year={2019}, month={Feb}, pages={217–237} } @article{im_chang_chee_chee_2019, title={The relationships of multiple factors to menopausal symptoms in different racial/ethnic groups of midlife women: The structural equation modeling}, volume={59}, ISSN={["1541-0331"]}, DOI={10.1080/03630242.2018.1450321}, abstractNote={ABSTRACT The purpose of the present study was to examine the relationships of multiple factors to menopausal symptoms in different racial/ethnic groups of midlife women. This secondary analysis was conducted with the data from 980 midlife women that were collected from 2005 to 2013 using the Midlife Women’s Symptom Index. Structural equation modeling was used to analyze the data. The model had the highest fit indices for non-Hispanic (NH) White midlife women, and prominent racial/ethnic differences were observed in the relationships of multiple factors to menopausal symptoms. In all racial/ethnic groups (except in Hispanic women), perceived health status was significantly positively associated with menopausal symptoms (β = −0.149 for NH African-American; β = −0.207 for NH Asians; β = −0.162 for NH Whites). Body mass index was significantly positively associated with menopausal symptoms only in NH Asians (β = 0.118) and Hispanics (β = 0.210). The racial/ethnic differences in the relationships of multiple factors to menopausal symptoms could have resulted from the different cultural contexts in which women undergo during their menopausal transitions. Further cultural studies on the associations of racial/ethnic-specific factors with menopausal symptoms would help in understanding possible causes for racial/ethnic differences in the factors significantly associated with menopausal symptoms.}, number={2}, journal={WOMEN & HEALTH}, author={Im, Eun-Ok and Chang, Sun Ju and Chee, Eunice and Chee, Wonshik}, year={2019}, month={Feb}, pages={196–212} } @article{im_hu_cheng_ko_chee_chee_2018, title={Clusters of midlife women identified by cognitive symptoms}, volume={110}, ISSN={["1873-4111"]}, DOI={10.1016/j.maturitas.2018.01.013}, abstractNote={Objectives The study aimed to identify clusters of midlife women by their cognitive symptoms and to examine racial/ethnic differences in the clusters. Study design This secondary analysis was conducted on the data from 1054 midlife women of multi-ethnic groups in two Internet studies (conducted from 2005 to 2013). Main outcome measures Only the data from the questions on background characteristics, health status, and menopausal status and the Cognitive Symptom Index for Midlife Women were used for this secondary analysis. The data were analyzed using factor analyses, hierarchical cluster analyses, chi-square tests, multinomial logistic analyses, and analyses of covariance. Results Four clusters were extracted: the low total symptom group (Cluster 1; 49.9%), the low-moderate total symptom group with high tertiary symptoms (Cluster 2; 17.3%), the high-moderate total symptom group with low tertiary symptoms (Cluster 3; 21.2%); and the high total symptom group (Cluster 4; 11.7%). There were significant differences in the level of education, employment status, family income, marital status, social support, the country of birth, race/ethnicity, body mass index, perceived general health, diagnosed disease(s), access to health care, and menopausal status among the clusters (p < .01). There were significant racial/ethnic differences in the total numbers and total severity scores of tertiary symptoms in Cluster 1. Also, there were significant racial/ethnic differences in individual symptoms in each cluster. Conclusions Racial/ethnic differences in midlife women’s cognitive symptoms and multiple factors that might differently influence their cognitive symptoms need to be considered in health care for midlife women in menopausal transition.}, journal={MATURITAS}, author={Im, Eun-Ok and Hu, Yun and Cheng, Ching-Yu and Ko, Young and Chee, Eunice and Chee, Wonshik}, year={2018}, month={Apr}, pages={33–40} } @article{im_chee_hu_kim_choi_hamajima_chee_2018, title={What to Consider in a Culturally Tailored Technology-Based Intervention?}, volume={36}, ISSN={["1538-9774"]}, DOI={10.1097/CIN.0000000000000450}, abstractNote={The purpose of this article is to identify practical issues in implementing a culturally tailored technology-based intervention among Asian American survivors of breast cancer. In a large-scale technology-based breast cancer intervention study, research team members wrote memos on issues in implementing a culturally tailored technology-based intervention and plausible reasons for the issues. Then, the content of the research diaries was analyzed, along with written records of the research team. The practical issues found in the research process included those related to (1) technology literacy and preferences; (2) language issues; (3) cultural attitudes, beliefs, and values; (4) intervention staff competence; (5) security and confidentiality issues; and (6) time and geographical constraints. Based on the issues, several recommendations are proposed for future research using culturally tailored technology-based interventions among racial and ethnic minorities.}, number={9}, journal={CIN-COMPUTERS INFORMATICS NURSING}, author={Im, Eun-Ok and Chee, Wonshik and Hu, Yun and Kim, Sangmi and Choi, Hanna and Hamajima, Yuko and Chee, Eunice}, year={2018}, month={Sep}, pages={424–429} }