Works (1)
Updated: July 5th, 2023 15:36
2017 journal article
Investigation of interfacial properties of pure and mixed poloxamers for surfactant-mediated shear protection of mammalian cells
COLLOIDS AND SURFACES B-BIOINTERFACES, 156, 358–365.
author keywords: Poloxamer; Mammalian cells; Shear sensitivity; Interfacial tension; Foam stability; Bioreactors
MeSH headings : Animals; CHO Cells; Cell Survival / drug effects; Cells, Cultured; Cricetulus; Poloxamer / chemistry; Poloxamer / pharmacology; Surface Tension; Surface-Active Agents / chemistry; Surface-Active Agents / pharmacology
TL;DR:
The mechanism of disruption by P407 was determined to be independent of cell-to-bubble attachment, suggesting that poloxamer adsorption to and subsequent reinforcement of the cell membrane may play a key role in protecting cells in high shear environments.
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UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
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