Emily Coffey

Works (1)

Updated: July 5th, 2023 15:43

2013 journal article

Expression of Fibroblast Growth Factor 9 in Normal Human Lung and Idiopathic Pulmonary Fibrosis

JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY, 61(9), 671–679.

By: E. Coffey n, D. Newman n & P. Sannes n

author keywords: smooth muscle cells; myofibroblast; metaplastic epithelium
MeSH headings : Adult; Cells, Cultured; Fibroblast Growth Factor 9 / analysis; Fibroblast Growth Factor 9 / metabolism; Humans; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Immunohistochemistry; Lung / metabolism; Lung / pathology; Lung / ultrastructure; Myocytes, Smooth Muscle / metabolism; Myocytes, Smooth Muscle / pathology; Myocytes, Smooth Muscle / ultrastructure; Myofibroblasts / metabolism; Myofibroblasts / pathology; Myofibroblasts / ultrastructure
TL;DR: Lungs of IPF patients expressed FGF9 in a population of myofibroblasts within fibroblastic foci, hypertrophic and hyperplastic epithelium of airways and alveoli, and smooth muscle cells surrounding vessels embedded in thickened interstitium, demonstrating a potentially strong candidate for contributing to the progression of IPf. (via Semantic Scholar)
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