Elisa Crisci

Also known as: Eli

https://orcid.org/0000-0002-4235-8508

virology, immunology, virus-host interactions, pig animal model

I think about myself as a "viro-immunologist". I have a veterinary background and I´' m working mainly in veterinary immunology and virology, mainly in pigs. I also worked in human viral infection research. I was always interested in innate immunity, mainly cellular responses, against viral infections. I have worked also in complement system, virus-like particles, different RNA and DNA viruses. I promote the use of pig as gold standard animal model for human research.

Works (42)

2020 journal article

Priming for welfare: gut microbiota is associated with equitation conditions and behavior in horse athletes

SCIENTIFIC REPORTS, 10(1).

By: N. Mach, A. Ruet, A. Clark, D. Bars-Cortina, Y. Ramayo-Caldas, E. Crisci, S. Pennarun, S. Dhorne-Pollet ...

Sources: Web Of Science, ORCID
Added: July 6, 2020

2019 journal article

Cellular Innate Immunity against PRRSV and Swine Influenza Viruses

Veterinary Sciences.

By: E. Crisci, L. Fraile & M. Montoya

Source: ORCID
Added: March 16, 2019

2019 journal article

HSV-2 Cellular Programming Enables Productive HIV Infection in Dendritic Cells

Frontiers in Immunology.

Source: ORCID
Added: December 12, 2019

2019 journal article

Macrophage-B Cell Interactions in the Inverted Porcine Lymph Node and Their Response to Porcine Reproductive and Respiratory Syndrome Virus

FRONTIERS IN IMMUNOLOGY, 10.

By: E. Bordet, M. Fretaud, E. Crisci, E. Bouguyon, S. Rault, J. Pezant, A. Pleau, P. Renson ...

Sources: Web Of Science, ORCID
Added: May 28, 2019

2019 journal article

Multi-species annotation of transcriptome and chromatin structure in domesticated animals.

BMC Biology, 12.

By: S. Foissac, S. Djebali, K. Munyard, N. Vialaneix, A. Rau, K. Muret, D. Esquerré, M. Zytnicki ...

Source: ORCID
Added: January 4, 2020

2019 journal article

The T-Cell Response to Type 2 Porcine Reproductive and Respiratory Syndrome Virus (PRRSV)

Viruses, 11(9), 796.

By: A. Kick, A. Amaral, L. Cortes, J. Fogle, E. Crisci, G. Almond, T. Käser

Source: ORCID
Added: August 30, 2019

2019 journal article

The miRNA-targeted transcriptome of porcine alveolar macrophages upon infection with Porcine Reproductive and Respiratory Syndrome Virus

SCIENTIFIC REPORTS, 9.

By: S. Dhorne-Pollet, E. Crisci, N. Mach, P. Renson, F. JaffreziC, G. Marot, T. Maroilley, M. Moroldo ...

Sources: ORCID, Web Of Science
Added: March 11, 2019

2018 journal article

Livestock genome annotation: transcriptome and chromatin structure profiling in cattle, goat, chicken and pig.

By: S. Foissac, S. Djebali, K. Munyard, N. Villa-Vialaneix, A. Rau, K. Muret, D. Esquerre, M. Zytnicki ...

Source: ORCID
Added: February 11, 2019

2018 journal article

Porcine Alveolar Macrophage-like cells are pro-inflammatory Pulmonary Intravascular Macrophages that produce large titers of Porcine Reproductive and Respiratory Syndrome Virus.

Scientific Reports, 7.

By: E. Bordet, P. Maisonnasse, P. Renson, E. Bouguyon, E. Crisci, M. Tiret, D. Descamps, C. Bernelin-Cottet ...

Source: ORCID
Added: February 11, 2019

2018 journal article

Porcine Reproductive and Respiratory Syndrome Virus Type 1.3 Lena Triggers Conventional Dendritic Cells 1 Activation and T Helper 1 Immune Response Without Infecting Dendritic Cells.

Frontiers in Immunology, 9.

By: E. Bordet, F. Blanc, M. Tiret, E. Crisci, E. Bouguyon, P. Renson, P. Maisonnasse, M. Bourge ...

Sources: NC State University Libraries, ORCID
Added: October 16, 2018

2017 journal article

HIV/Human herpesvirus co-infections: Impact on tryptophan-kynurenine pathway and immune reconstitution.

PloS One.

Source: ORCID
Added: February 11, 2019

2017 conference paper

Integrative and differential analysis of transcriptomes and chromatin accessibility regions reveals regulatory mechanisms involved in pig immune and metabolic functions

36th International Society for Animal Genetics Conference, np.

By: S. Quelen, K. Munyard, N. Villa-Vialaneix, C. Cabau, A. Rau, E. Crisci, T. Derrien, C. Klopp, M. Zytnicki, S. Lagarrigue

Source: ORCID
Added: February 11, 2019

2017 journal article

Pig as a biomedical model: Putting the porcine lung dendritic cells/macrophages network into light

Revue Des Maladies Respiratoires, 34, A328.

By: P. Maisonnasse, E. Bouguyon, M. Bourge, G. Piton, A. Ezquerra, C. Deloizy, C. Urien, J. Leplat, G. Simon, C. Chevalier

Source: ORCID
Added: February 11, 2019

2016 journal article

Complement Opsonization Promotes Herpes Simplex Virus 2 Infection of Human Dendritic Cells.

Journal of Virology, 90(10), 4939–4950,

By: E. Crisci, R. Ellegård, S. Nyström, E. Rondahl, L. Serrander, T. Bergström, C. Sjöwall, K. Eriksson, M. Larsson

Source: ORCID
Added: February 11, 2019

2016 journal article

Rabbit hemorrhagic disease virus capsid, a versatile platform for foreign B-cell epitope display inducing protective humoral immune responses.

Scientific Reports, 6, 31844,

By: N. Moreno, I. Mena, I. Angulo, Y. Gómez, E. Crisci, M. Montoya, E. Blanco, J. Bárcena

Source: ORCID
Added: February 11, 2019

2015 journal article

Impaired NK Cell Activation and Chemotaxis toward Dendritic Cells Exposed to Complement-Opsonized HIV-1.

Journal of Immunology (Baltimore.

By: R. Ellegård, E. Crisci, J. Andersson, E. Shankar, S. Nyström, J. Hinkula, M. Larsson

Source: ORCID
Added: February 11, 2019

2015 journal article

The respiratory DC/macrophage network at steady-state and upon influenza infection in the swine biomedical model.

Mucosal Immunology.

By: P. Maisonnasse, E. Bouguyon, G. Piton, A. Ezquerra, C. Urien, C. Deloizy, M. Bourge, J. Leplat ...

Source: ORCID
Added: February 11, 2019

2014 journal article

Complement Opsonization of HIV-1 Results in Decreased Antiviral and Inflammatory Responses in Immature Dendritic Cells via CR3.

Journal of Immunology, 193(9), 4590–4601.

By: R. Ellegård, E. Crisci, A. Burgener, C. Sjöwall, K. Birse, G. Westmacott, J. Hinkula, J. Lifson, M. Larsson

Source: ORCID
Added: February 11, 2019

2014 journal article

Immune characterization of long pentraxin 3 in pigs infected with influenza virus.

Veterinary Microbiology, 168(1), 185–192.

By: E. Crisci, L. Fraile, S. Valentino, L. Martínez-Guinó, B. Bottazzi, A. Mantovani, M. Montoya

Source: ORCID
Added: February 11, 2019

2014 journal article

In vivo tracking and immunological properties of pulsed porcine monocyte-derived dendritic cells.

Molecular Immunology.

By: E. Crisci, L. Fraile, R. Novellas, Y. Espada, R. Cabezón, J. Martínez, L. Cordoba, J. Bárcena, D. Benitez-Ribas, M. Montoya

Source: ORCID
Added: February 11, 2019

2013 journal article

Review: influenza virus in pigs.

Molecular Immunology, 55(3-4), 200–211.

By: E. Crisci, T. Mussá, L. Fraile & M. Montoya

Source: ORCID
Added: February 11, 2019

2013 journal article

Seudopart́ıculas virales como vacunas v́ıricas en veterinaria

Inmunoloǵıa (1987), 102–106.

Source: ORCID
Added: February 11, 2019

2013 journal article

Virus-like particle-based vaccines for animal viral infections

Inmunología, 32(3), 102–116.

By: E. Crisci, J. Bárcena & M. Montoya

Source: ORCID
Added: February 11, 2019

2012 journal article

Chimeric calicivirus-like particles elicit specific immune responses in pigs.

30(14), 2427–2439.

By: E. Crisci, L. Fraile, N. Moreno, E. Blanco, R. Cabezón, C. Costa, T. Mussá, M. Baratelli ...

Source: ORCID
Added: February 11, 2019

2012 journal article

Immunogenic properties of calicivirus-like particles as vaccine vectors

By: E. Crisci & J. Segalés Coma

Source: ORCID
Added: February 11, 2019

2012 journal article

Immunomodulatory properties of beta-sitosterol in pig immune responses.

International Immunopharmacology, 13(3), 316–321.

By: L. Fraile, E. Crisci, L. Córdoba, M. Navarro, J. Osada & M. Montoya

Source: ORCID
Added: February 11, 2019

2012 journal article

Virus-like particles: the new frontier of vaccines for animal viral infections.

Veterinary Immunology and Immunopathology, 148(3-4), 211–225.

By: E. Crisci, J. Bárcena & M. Montoya

Source: ORCID
Added: February 11, 2019

2012 journal article

phenoypical characterization and isolation of a subpopulation of myeloid cells from swine peripheral blood: new method to isolate plasmacytoid dendritic cells: p0920

Immunology, 137, 482.

By: P. Martinez-Orellana, M. Cortes, C. Rodriguez-Carino, L. Córdoba, R. Maeso, E. Crisci, S. Chamorro, P. Martinez, J. Dominguez, M. Montoya

Source: ORCID
Added: February 11, 2019

2011 journal article

DC2010: Forum on Vaccine Science

Inmunología, 30(3), 100–104.

By: P. Bastos, D. Benitez-Ribas, E. Crisci, M. Naranjo, B. Pérez-Cabezas & M. Montoya

Source: ORCID
Added: February 11, 2019

2011 journal article

Interaction of porcine conventional dendritic cells with swine influenza virus.

420(2), 125–134.

By: T. Mussá, C. Rodriguez-Cariño, M. Pujol, L. Córdoba, N. Busquets, E. Crisci, J. Dominguez, L. Fraile, M. Montoya

Source: ORCID
Added: February 11, 2019

2010 journal article

Corrigendum to “A proposal on porcine circovirus type 2 (PCV2) genotype definition and their relation with postweaning multisystemic wasting syndrome (PMWS) occurrence”[Vet. Microbiol. 128 (2008) 23--25]

Veterinary Microbiology, 141(1), 194.

By: L. Grau-Roma, E. Crisci, M. Sibila, S. Lopez-Soria, M. Nofrarı́as, M. Cortey, L. Fraile, A. Olvera, J. Segales

Source: ORCID
Added: February 11, 2019

2010 journal article

Estudien el paper de la citoquina IL-10 en el desenvolupament de la circovirosi porcina

UAB Divulga, 0001–0002.

By: E. Crisci & M. Montoya González

Source: ORCID
Added: February 11, 2019

2010 journal article

Experimental infection with H1N1 European swine influenza virus protects pigs from an infection with the 2009 pandemic H1N1 human influenza virus.

Veterinary Research, 41(5), 74.

By: N. Busquets, J. Segalés, L. Córdoba, T. Mussá, E. Crisci, G. Martín-Valls, M. Simon-Grifé, M. Pérez-Simó ...

Source: ORCID
Added: February 11, 2019

2010 journal article

Increased numbers of myeloid and lymphoid IL-10 producing cells in spleen of pigs with naturally occurring postweaning multisystemic wasting syndrome

Veterinary Immunology and Immunopathology, 136(3-4), 305–310.

Source: ORCID
Added: February 11, 2019

2010 journal article

Increased numbers of myeloid and lymphoid IL-10 producing cells in spleen of pigs with naturally occurring postweaning multisystemic wasting syndrome.

Veterinary Immunology and Immunopathology, 136(3-4), 305–310.

By: E. Crisci, M. Ballester, J. Domínguez, J. Segalés & M. Montoya

Source: ORCID
Added: February 11, 2019

2010 journal article

Interferon-gamma induction correlates with protection by DNA vaccine expressing E2 glycoprotein against classical swine fever virus infection in domestic pigs.

Veterinary Microbiology, 142(1-2), 51–58.

By: J. Tarradas, J. Argilaguet, R. Rosell, M. Nofrarías, E. Crisci, L. Córdoba, E. Pérez-Martín, I. Díaz ...

Source: ORCID
Added: February 11, 2019

2009 journal article

A genetically engineered chimeric vaccine against porcine circovirus type 2 (PCV2) improves clinical, pathological and virological outcomes in postweaning multisystemic wasting syndrome affected farms.

27(52), 7313–7321.

By: J. Segalés, A. Urniza, A. Alegre, T. Bru, E. Crisci, M. Nofrarías, S. López-Soria, M. Balasch ...

Source: ORCID
Added: February 11, 2019

2009 journal article

Chimeric calicivirus-like particles elicit protective anti-viral cytotoxic responses without adjuvant.

387(2), 303–312.

By: E. Crisci, H. Almanza, I. Mena, L. Córdoba, E. Gómez-Casado, L. Fraile, J. Bárcena, M. Montoya

Source: ORCID
Added: February 11, 2019

2009 article

Effect of treatment with phytosterols in three herds with porcine respiratory disease complex.

LorenzoJ, F., Elisa, C., Joan, W., Montse, A., Lorenzo, M., Lara, R., … María, M. (2009, January). Journal of Swine Health and Production, Vol. 17, pp. 32–41,

By: F. LorenzoJ, C. Elisa, W. Joan, A. Montse, M. Lorenzo, R. Lara, B. Santi, M. María

Source: ORCID
Added: February 11, 2019

2008 journal article

A proposal on porcine circovirus type 2 (PCV2) genotype definition and their relation with postweaning multisystemic wasting syndrome (PMWS) occurrence.

Veterinary Microbiology, 128(1-2), 23–35.

By: L. Grau-Roma, E. Crisci, M. Sibila, S. López-Soria, M. Nofrarias, M. Cortey, L. Fraile, A. Olvera, J. Segalés

Source: ORCID
Added: February 11, 2019

2008 conference paper

Suvaxyn® Circo ameliorates PCV2-associated lymphoid lesions and PMWS-associated mortality

20th INTERNATIONAL PIG VETERINARY SOCIETY CONGRESS, 18.

By: J. Segalés, A. Urniza, A. Alegre, E. Crisci, M. Pérez, M. Nofrarı́as, M. Balasch, Z. Xu, H. Chu, J. Plana-Duran

Source: ORCID
Added: February 11, 2019

conference paper

IMMUNOMODULATION IN PRRS MLV VACCINATION

Fraile, L., Crisci, E., Gimeno, M., Diaz, I., Mateu, E., & Montoya, M. 20th INTERNATIONAL PIG VETERINARY SOCIETY CONGRESS, 21.

By: L. Fraile, E. Crisci, M. Gimeno, I. Diaz, E. Mateu & M. Montoya

Source: ORCID
Added: February 11, 2019

Employment

2018 - present

North Carolina State University Raleigh, NC, US
Assistant Professor Population Health and Pathobiology

2017 - 2018

INRA Centre de Jouy-en-Josas Jouy-en-Josas, Île-de-France, FR
Post doc GABI, VIM

2015 - 2016

Linköpings Universitet Institutionen för klinisk och experimentell medicin Linkoping, Region Östergötland, SE
Postdoctoral scientist Molecular Virology

2015 - 2015

Universitetssjukhuset i Linköping Linkoping, Region Östergötland, SE
Technician Clinical immunology and transfusion medicine

2013 - 2015

Linköpings Universitet Institutionen för klinisk och experimentell medicin Linköping, SE
Post Doc Molecular Virology

2012 - 2012

CRESA Bellaterra, Catalunya, ES
Post Doc

2007 - 2011

CRESA Bellaterra, Catalunya, ES
PhD

2011 - 2011

Walter and Eliza Hall Institute of Medical Research Melbourne, VIC, AU
Visiting PhD student Inflammation division

2010 - 2010

CISA-INIA Madrid, ES
Visiting PhD student CISA

2009 - 2009

Universiteit Gent Gent, BE
Visiting PhD student Faculty of Veterinary Medicine, Virology lab.

2008 - 2008

University of Aberdeen Aberdeen, Aberdeen, GB
Visiting PhD student Institute of Medical Science

2007 - 2007

CRESA Bellaterra, Catalunya, ES
Master Student

Education

2007 - 2011

Universitat Autònoma de Barcelona Bellaterra, Catalunya, ES
PhD in Animal Health and Medicine with Special Award CRESA

2006 - 2007

Universitat Autònoma de Barcelona Bellaterra, Catalunya, ES
Master of Science in Veterinary research Veterinary faculty

1997 - 2005

Facolta di Medicina Veterinaria Bologna, Emilia-Romagna, IT
DVM with honors degree

Funding History

Funding history based on the linked ORCID record.

grant September 1, 2019 - May 1, 2020
Immunogenomics of porcine lung cells during PRRSV-2 infection
College of Veterinary Medicine, North Carolina State University
grant June 1, 2019 - June 1, 2021
Define Long Non-coding RNA Regulatory Mechanisms of Host Response to Influenza Infection
NIAID Bioinformatics Research Center
grant January 1, 2019 - January 1, 2020
Understanding Porcine Respiratory Disease Complex and How to Prevent It
North Carolina Pork Council
salary-award September 1, 2017 - January 1, 2018
P.I.G. Pig Immunity Genomics
European Commission
award April 1 - July 1, 2011
Dendritic cells techniques
Ministerio de Ciencia e Innovación
award February 1 - May 1, 2010
Virus like particle production
Ministerio de Ciencia e Innovación
award March 1 - July 1, 2009
Influenza virus techniques
Ministerio de Ciencia e Innovación
award June 1 - August 1, 2008
Laser microdissection tecnique
Secretaría Nacional de Ciencia, Tecnología e Innovación