Works (5)

Updated: November 20th, 2025 13:58

2025 article

Single-cell transcriptomics predict novel potential regulators of acute epithelial restitution in the ischemia-injured intestine

Rose, E. C., Simon, J. M., Gomez-Martinez, I., Magness, S. T., Odle, J., Blikslager, A. T., & Ziegler, A. L. (2025, January 24). American Journal of Physiology-Gastrointestinal and Liver Physiology, Vol. 3.

By: E. Rose n, J. Simon*, I. Gomez-Martinez*, S. Magness*, J. Odle n, A. Blikslager n, A. Ziegler n

author keywords: barrier function; intestinal ischemia; restitution
MeSH headings : Animals; Intestinal Mucosa / metabolism; Swine; Enterocytes / metabolism; Enterocytes / pathology; Transcriptome; Ischemia / metabolism; Ischemia / genetics; Jejunum / metabolism; Jejunum / pathology; Macrophage Colony-Stimulating Factor / metabolism; Macrophage Colony-Stimulating Factor / genetics; Single-Cell Analysis; Disease Models, Animal; Cell Movement; Animals, Newborn; Gene Expression Profiling / methods
topics (OpenAlex): Barrier Structure and Function Studies; Clinical Nutrition and Gastroenterology; Immune cells in cancer
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 24, 2025

2025 article

Structure-guided design of a synthetic bile acid that inhibits Clostridioides difficile TcdB toxin

Miletic, S., Icho, S., Li, Z., Tam, J., Rose, E. C., Perkins, C. E., … Melnyk, R. A. (2025, November 18). Nature Microbiology.

By: S. Miletic*, S. Icho*, Z. Li*, J. Tam*, E. Rose n, C. Perkins n, A. Nakhi*, X. Yang* ...

topics (OpenAlex): Clostridium difficile and Clostridium perfringens research; Bacillus and Francisella bacterial research; Antimicrobial Resistance in Staphylococcus
Source: NC State University Libraries
Added: November 19, 2025

2022 article

Oropharyngeal Shedding of Gammaherpesvirus DNA by Cats, and Natural Infection of Salivary Epithelium

Rose, E. C., Tse, T. Y., Oates, A. W., Jackson, K., Pfeiffer, S., Donahoe, S. L., … Pesavento, P. A. (2022, March 9). Viruses.

By: E. Rose n, T. Tse*, A. Oates*, K. Jackson*, S. Pfeiffer*, S. Donahoe*, L. Setyo*, V. Barrs*, J. Beatty*, P. Pesavento*

author keywords: feline; gammaherpesvirus; oncogenesis; shedding; transmission; carcinoma
MeSH headings : Animals; Carcinoma / complications; Cat Diseases; Cats; DNA, Viral / genetics; Epithelium; Female; Gammaherpesvirinae / genetics; Herpesviridae Infections; Oropharynx; Prospective Studies; Retrospective Studies; Virus Shedding
topics (OpenAlex): Herpesvirus Infections and Treatments; Viral-associated cancers and disorders; Virus-based gene therapy research
TL;DR: Data support the oronasopharynx as a site of FcaGHV1 shedding, particularly after maternal antibodies are expected to decline, and the salivary epithelium is identified as a potential site ofFcaGHVs1 persistence. (via Semantic Scholar)
Source: Web Of Science
Added: April 18, 2022

2022 article

Porcine Models of the Intestinal Microbiota: The Translational Key to Understanding How Gut Commensals Contribute to Gastrointestinal Disease

Rose, E. C., Blikslager, A. T., & Ziegler, A. L. (2022, March 25). Frontiers in Veterinary Science.

By: E. Rose n, A. Blikslager n & A. Ziegler n

author keywords: intestinal microbiota; translational models; pig models; gut commensals; gastrointestinal disease
topics (OpenAlex): Gut microbiota and health; Gastrointestinal motility and disorders; Clostridium difficile and Clostridium perfringens research
TL;DR: To further elucidate the pathogenesis of these disease syndromes as well as uncover novel therapies and preventative measures, gastrointestinal researchers should consider the pig as a powerful, translational model of the gastrointestinal microbiota. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: May 23, 2022

2021 journal article

Probiotics, Prebiotics and Epithelial Tight Junctions: A Promising Approach to Modulate Intestinal Barrier Function

International Journal of Molecular Sciences, 22(13), 6729.

By: E. Rose n, J. Odle n, A. Blikslager n & A. Ziegler n

author keywords: probiotics; prebiotics; bioactive compounds; intestinal barrier function; tight junctions; toll-like receptors; intestinal microbiota
MeSH headings : Gastrointestinal Microbiome / drug effects; Gastrointestinal Microbiome / physiology; Humans; Infant; Intestinal Mucosa / cytology; Intestinal Mucosa / drug effects; Intestinal Mucosa / physiology; Prebiotics; Probiotics / pharmacology; Tight Junction Proteins / metabolism; Tight Junctions / metabolism; Toll-Like Receptors / metabolism
topics (OpenAlex): Barrier Structure and Function Studies; Gut microbiota and health; Oral microbiology and periodontitis research
TL;DR: Current views on the effects of pro- and prebiotics on the intestinal epithelial barrier as well as on non-epithelial cell barrier constituents, such as the enteric glial cell network are summarized. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries, Crossref
Added: June 24, 2021

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