@article{rostom_goya-jorge_muro_boubrik_wiorek_karaky_kassab_rodriquez_veitia_2024, title={Fishing antioxidant 4-hydroxycoumarin derivatives: synthesis, characterization, and in vitro assessments}, ISSN={["1205-7541"]}, DOI={10.1139/cjpp-2023-0455}, journal={CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY}, author={Rostom, Batoul and Goya-Jorge, Elizabeth and Muro, Liliana Vicet and Boubrik, Imrane and Wiorek, Sarah and Karaky, Racha and Kassab, Issam and Rodriquez, Maria Elisa Jorge and Veitia, Maite Sylla-Iyarreta}, year={2024}, month={Apr} }
 @article{goya-jorge_gonza_douny_scippo_delcenserie_2024, title={M-Batches to Simulate Luminal and Mucosal Human Gut Microbial Ecosystems: A Case Study of the Effects of Coffee and Green Tea}, volume={12}, ISSN={["2076-2607"]}, DOI={10.3390/microorganisms12020236}, abstractNote={Gastrointestinal simulations in vitro have only limited approaches to analyze the microbial communities inhabiting the mucosal compartment. Understanding and differentiating gut microbial ecosystems is crucial for a more comprehensive and accurate representation of the gut microbiome and its interactions with the host. Herein is suggested, in a short-term and static set-up (named “M-batches”), the analysis of mucosal and luminal populations of inhabitants of the human colon. After varying several parameters, such as the fermentation volume and the fecal inoculum (single or pool), only minor differences in microbial composition and metabolic production were identified. However, the pool created with feces from five donors and cultivated in a smaller volume (300 mL) seemed to provide a more stable luminal ecosystem. The study of commercially available coffee and green tea in the M-batches suggested some positive effects of these worldwide known beverages, including the increase in butyrate-producing bacteria and lactobacilli populations. We hope that this novel strategy can contribute to future advances in the study of intestinal ecosystems and host-microbe relationships and help elucidate roles of the microbiome in health and disease.}, number={2}, journal={MICROORGANISMS}, author={Goya-Jorge, Elizabeth and Gonza, Irma and Douny, Caroline and Scippo, Marie-Louise and Delcenserie, Veronique}, year={2024}, month={Feb} }