Elizabeth Divito

College of Agriculture and Life Sciences

2020 journal article

Impact of radiation dose and pre-treatment pain levels on survival in dogs undergoing radiotherapy with or without chemotherapy for presumed extremity osteosarcoma

VETERINARY AND COMPARATIVE ONCOLOGY, 18(4), 538–547.

By: M. Nolan n, N. Green n, E. DiVito n, B. Lascelles n & S. Haney*

author keywords: analgesia; appendicular bone tumour; malignant osteolysis; palliative; primary bone tumour; radiosurgery
MeSH headings : Animals; Antineoplastic Agents / therapeutic use; Bone Neoplasms / drug therapy; Bone Neoplasms / mortality; Bone Neoplasms / radiotherapy; Bone Neoplasms / veterinary; Dog Diseases / drug therapy; Dog Diseases / mortality; Dog Diseases / radiotherapy; Dogs; Female; Fractures, Bone / complications; Fractures, Bone / veterinary; Lung Neoplasms / radiotherapy; Lung Neoplasms / secondary; Male; North Carolina / epidemiology; Osteosarcoma / drug therapy; Osteosarcoma / mortality; Osteosarcoma / radiotherapy; Osteosarcoma / veterinary; Pain / veterinary; Radiation Dosage; Radiotherapy / methods; Radiotherapy / veterinary; Retrospective Studies; Survival
TL;DR: In a univariate analysis, dogs with pulmonary metastases and high pain at the time of irradiation had short overall survival times; use of high radiation doses and chemotherapy were associated with improved survival. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 10, 2020

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