Works (10)

Updated: July 5th, 2023 15:35

2021 journal article

Fibrin-modulating nanogels for treatment of disseminated intravascular coagulation

BLOOD ADVANCES, 5(3), 613–627.

By: E. Mihalko n, M. Sandry n, N. Mininni n, K. Nellenbach n, H. Deal n, M. Daniele n, K. Ghadimi*, J. Levy*, A. Brown n

MeSH headings : Disseminated Intravascular Coagulation / drug therapy; Fibrin; Humans; Microcirculation; Nanogels; Thrombosis / drug therapy
Source: Web Of Science
Added: March 22, 2021

2021 article

Fibrin-specific poly(N-isopropylacrylamide) nanogels for targeted delivery of tissue-type plasminogen activator to treat thrombotic complications are well tolerated in vivo

Mihalko, E. P., Nellenbach, K., Krishnakumar, M., Moiseiwitsch, N., Sollinger, J., Cooley, B. C., & Brown, A. C. (2021, December 11). BIOENGINEERING & TRANSLATIONAL MEDICINE.

By: E. Mihalko n, K. Nellenbach n, M. Krishnakumar n, N. Moiseiwitsch n, J. Sollinger n, B. Cooley*, A. Brown n

author keywords: disseminated intravascular coagulation; fibrin; nanogels; pNIPAM; targeted delivery; thrombosis; tissue plasminogen activator
Source: Web Of Science
Added: December 20, 2021

2021 article

Multivalent Aptamer-Functionalized Single-Strand RNA Origami as Effective, Target-Specific Anticoagulants with Corresponding Reversal Agents

Krissanaprasit, A., Key, C. M., Froehlich, K., Pontula, S., Mihalko, E., Dupont, D. M., … LaBean, T. H. (2021, April 21). ADVANCED HEALTHCARE MATERIALS.

By: A. Krissanaprasit n, C. Key n, K. Froehlich n, S. Pontula, E. Mihalko n, D. Dupont*, E. Andersen*, J. Kjems*, A. Brown n, T. LaBean n

author keywords: anticoagulants; aptamers; direct thrombin inhibitors; nucleic acids; reversal agents; RNA nanotechnology; RNA origami
MeSH headings : Anticoagulants / pharmacology; Aptamers, Nucleotide / pharmacology; Blood Coagulation; RNA / pharmacology; Thrombin
Source: Web Of Science
Added: June 10, 2021

2021 article

Platelet-like particles reduce coagulopathy-related and neuroinflammatory pathologies post-experimental traumatic brain injury

Todd, J., Bharadwaj, V. N., Nellenbach, K., Nandi, S., Mihalko, E., Copeland, C., … Stabenfeldt, S. E. (2021, June 11). JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS.

By: J. Todd*, V. Bharadwaj*, K. Nellenbach n, S. Nandi n, E. Mihalko n, C. Copeland*, A. Brown n, S. Stabenfeldt*

author keywords: blood-brain barrier; coagulopathy; neuroinflammation; permeability; platelet-like particles; traumatic brain injury
MeSH headings : Animals; Blood Platelets / metabolism; Blood-Brain Barrier / metabolism; Brain Injuries, Traumatic / complications; Brain Injuries, Traumatic / drug therapy; Brain Injuries, Traumatic / metabolism; Disease Models, Animal; Mice; Microglia / metabolism
Source: Web Of Science
Added: June 21, 2021

2021 journal article

Synthetic Platelet Microgels Containing Fibrin Knob B Mimetic Motifs Enhance Clotting Responses


By: S. Nandi n, E. Mihalko n, K. Nellenbach n, M. Castaneda n, J. Schneible n, M. Harp*, H. Deal n, M. Daniele n ...

author keywords: bleeding; Clotting; fibrin; hemostasis; microgel
Sources: Web Of Science, ORCID
Added: April 5, 2021

2020 review

Clot Structure and Implications for Bleeding and Thrombosis


By: E. Mihalko n & A. Brown n

author keywords: fibrin; clot structure; atomic force microscopy; fibrinolysis; thrombosis
MeSH headings : Fibrin / metabolism; Fibrinolysis; Hemorrhage / metabolism; Hemorrhage / pathology; Humans; Thrombosis / metabolism; Thrombosis / pathology
Source: Web Of Science
Added: February 27, 2020

2020 journal article

Nanosilver composite pNIPAm microgels for the development of antimicrobial platelet-like particles


By: E. Chee n, S. Nandi n, K. Nellenbach n, E. Mihalko n, D. Snider n, L. Morrill n, A. Bond n, E. Sproul n ...

author keywords: antimicrobial; microgels; nanosilver; platelet-mimetic; wound healing
MeSH headings : Acrylic Resins / chemistry; Animals; Anti-Infective Agents / chemistry; Anti-Infective Agents / pharmacology; Bacterial Infections / drug therapy; Bacterial Infections / microbiology; Blood Platelets; Clot Retraction; Colony-Forming Units Assay; Fibrin / chemistry; Fibrin / immunology; Gels; Hemorrhage / drug therapy; Hemostasis / drug effects; Liver / injuries; Male; Metal Nanoparticles; Mice; Mice, Inbred C57BL; Microgels; Silver / administration & dosage; Silver / chemistry; Wound Healing
Sources: Web Of Science, ORCID
Added: March 16, 2020

2020 journal article

Platelet-like particles improve fibrin network properties in a hemophilic model of provisional matrix structural defects


By: S. Nandi n, L. Sommerville*, K. Nellenbach n, E. Mihalko n, M. Erb n, D. Freytes n, M. Hoffman*, D. Monroe*, A. Brown n

author keywords: Fibrin; Biomimetic; Platelet; Hemophilia; Biomaterials
MeSH headings : Blood Coagulation; Blood Platelets; Fibrin; Plasma; Wound Healing
Source: Web Of Science
Added: August 24, 2020

2018 review

Material Strategies for Modulating Epithelial to Mesenchymal Transitions

[Review of ]. ACS BIOMATERIALS SCIENCE & ENGINEERING, 4(4), 1149–1161.

By: E. Mihalko n & A. Brown n

author keywords: epithelial to mesenchymal transition; EMT; mechanotransduction; fibrosis; development; transforming growth factor beta; EndoMT
Source: Web Of Science
Added: August 6, 2018

2018 journal article

Targeted repair of heart injury by stem cells fused with platelet nanovesicles


By: J. Tang n, T. Su n, K. Huang, P. Dinh n, Z. Wang*, A. Vandergriff n, M. Hensley n, J. Cores n ...

Sources: Web Of Science, ORCID
Added: August 6, 2018