Emma Nixon

Works (12)

Updated: September 18th, 2024 05:01

2024 journal article

Percutaneous Absorption of Fireground Contaminants: Naphthalene, Phenanthrene, and Benzo[a]pyrene in Porcine Skin in an Artificial Sweat Vehicle

TOXICS, 12(8).

By: C. Probert n, E. Nixon n , R. Ormond n  & R. Baynes n 

author keywords: dermal absorption; polycyclic aromatic hydrocarbons; benzo[a]pyrene; porcine skin; fireground contaminants; firefighter
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 15, 2024

2022 article

Pharmacokinetic/pharmacodynamic modeling of ketoprofen and flunixin at piglet castration and tail-docking

Nixon, E., Chittenden, J. T., Baynes, R. E., & Messenger, K. M. (2022, July 14). JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, Vol. 7.

By: E. Nixon n , J. Chittenden*, R. Baynes n  & K. Messenger n

author keywords: NSAID; pain; pharmacodynamics; pharmacokinetics; piglet
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal; Clonixin / analogs & derivatives; Dinoprostone; Hydrocortisone; Ketoprofen / pharmacology; Ketoprofen / therapeutic use; Male; Orchiectomy / veterinary; Pain / veterinary; Swine; Tail
TL;DR: Flunixin may be the best NSAID to use in mitigating castration and tail‐docking pain at the current label dose of ketoprofen. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: July 16, 2022

2022 journal article

The pharmacokinetics of transdermal flunixin in lactating dairy goats

JOURNAL OF DAIRY SCIENCE, 105(1), 549–559.

By: E. Meira n, E. Wiloch n, E. Nixon n , J. Yeatts n, F. Sheela n, G. Smith n , R. Baynes n 

author keywords: transdermal flunixin; goat; pharmacokinetics; drug residue; milk
MeSH headings : Administration, Cutaneous; Animals; Anti-Inflammatory Agents, Non-Steroidal; Cattle; Clonixin / analogs & derivatives; Female; Goats; Lactation; Milk / chemistry
TL;DR: Evaluated the pharmacokinetics of transdermal flunixin in dairy goats to determine a milk withdrawal interval (WDI) to avoid violative residue contamination in the food supply and propose safe residue levels in goat milk provides a milk WDI of 60 h using the US Food and Drug Administration tolerance limit method. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: October 17, 2021

2021 journal article

Antiviral Efficacy of Metal and Metal Oxide Nanoparticles against the Porcine Reproductive and Respiratory Syndrome Virus

Nanomaterials.

By: S. Graham *, Y. Cheong *, S. Furniss*, E. Nixon* , J. Smith *, X. Yang*, R. Fruengel *, S. Hussain* ...

author keywords: porcine reproductive and respiratory syndrome virus; antiviral nanoparticle; viricidal efficacy; staphylococcus aureus
TL;DR: Data support the further evaluation of these AVNP as candidate nanoparticles for incorporation into antimicrobial air-filtration systems to reduce transmission of PRRSV and other airborne pathogens. (via Semantic Scholar)
Source: ORCID
Added: August 23, 2021

2021 journal article

Comparative effects of nonsteroidal anti-inflammatory drugs at castration and tail-docking in neonatal piglets

PLOS ONE, 16(11).

By: E. Nixon n , A. Carlson  n, P. Routh n, L. Hernandez n, G. Almond n , R. Baynes n , K. Messenger n

Ed(s): J. Loor

MeSH headings : Animal Husbandry / methods; Animals; Animals, Newborn; Anti-Inflammatory Agents, Non-Steroidal / therapeutic use; Castration / adverse effects; Castration / methods; Clonixin / analogs & derivatives; Clonixin / therapeutic use; Dinoprostone / analysis; Extracellular Fluid / chemistry; Hydrocortisone / blood; Ketoprofen / therapeutic use; Male; Meloxicam / therapeutic use; Pain / drug therapy; Pain / etiology; Pain Management; Swine; Tail
TL;DR: It is demonstrated that management strategies including administration of intramuscular flunixin or ketoprofen to reduce pain associated with processing will likely improve piglet health and welfare in the United States. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
13. Climate Action (Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: December 1, 2021

2021 journal article

EVALUATION OF THE PHARMACOKINETIC BEHAVIOR OF TULATHROMYCIN (DRAXXIN) IN FLORIDA MANATEES (TRICHECHUS MANATUS LATIROSTRIS) UNDERGOING MEDICAL REHABILITATION

JOURNAL OF ZOO AND WILDLIFE MEDICINE, 52(3), 880–885.

By: L. Smith *, C. Bublitz n, E. Nixon n , J. Yeatts n, R. Ball * & R. Baynes n 

MeSH headings : Animals; Animals, Wild; Cattle; Disaccharides; Heterocyclic Compounds; Horses; Swine; Trichechus; Trichechus manatus
TL;DR: The pharmacokinetic behavior of tulathromycin in Florida manatees can be used to optimize dosage regimens in this species, and this antibiotic has also been used in manatee with positive clinical outcomes. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: October 2, 2021

2021 journal article

Non-Steroidal Anti-Inflammatory Drugs: Pharmacokinetics and Mitigation of Procedural-Pain in Cattle

ANIMALS, 11(2).

By: B. Wagner n, E. Nixon n , I. Robles n , R. Baynes n , J. Coetzee * & M. Pairis-Garcia n 

author keywords: cattle; NSAID; flunixin; meloxicam; aspirin; pain control
TL;DR: A comprehensively evaluated existing literature to summarize three NSAIDs (meloxicam, flunixin and aspirin) pharmacokinetics and administration outcome in regard to pain control during castration and disbudding procedures, in cattle. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: January 27, 2021

2021 journal article

Producer and Veterinarian Perspectives towards Pain Management Practices in the US Cattle Industry

ANIMALS, 11(1).

By: I. Robles n , A. Arruda *, E. Nixon n , E. Johnstone *, B. Wagner n, L. Edwards-Callaway *, R. Baynes n , J. Coetzee *, M. Pairis-Garcia n 

author keywords: cattle; animal welfare; pain mitigation; analgesics; attitudes; survey; FARAD
TL;DR: This study explored producer and veterinarian perspectives on pain management practices by exploring inquires received by Food Animal Residue Avoidance Databank (FARAD) regarding analgesic use in cattle and using a survey instrument to identify factors that impact pain management implementation in the US cattle industry. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: January 21, 2021

2020 journal article

Comparative Plasma and Interstitial Fluid Pharmacokinetics of Meloxicam, Flunixin, and Ketoprofen in Neonatal Piglets

FRONTIERS IN VETERINARY SCIENCE, 7.

By: E. Nixon n , G. Almond n , R. Baynes n  & K. Messenger n

author keywords: piglet; pain; welfare; castration; NSAID; pharmacokinetics; interstitial fluid
TL;DR: If drug concentrations in the ISF are more closely related to efficacy than the plasma, then the delay between the Tmax in plasma and ISF may be relevant to the timing of castration in order to provide the greatest analgesic effect. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 30, 2020

2020 journal article

Plasma, urine and tissue concentrations of Flunixin and Meloxicam in Pigs

BMC VETERINARY RESEARCH, 16(1).

By: E. Nixon n , T. Mays*, P. Routh n, J. Yeatts n, V. Fajt *, T. Hairgrove *, R. Baynes n 

author keywords: Pig; Flunixin; Meloxicam; Pharmacokinetics; NSAIDs; Residue; Urine; Show
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / pharmacokinetics; Clonixin / analogs & derivatives; Clonixin / blood; Clonixin / pharmacokinetics; Clonixin / urine; Half-Life; Injections, Intramuscular / veterinary; Kidney / chemistry; Liver / chemistry; Male; Meloxicam / blood; Meloxicam / pharmacokinetics; Meloxicam / urine; Sus scrofa
TL;DR: The data suggest that pigs given a single intramuscular dose of meloxicam or flunixin are likely to have detectable levels of the parent drug in urine up to 2 days and 5 days, respectively, after the first dose, but unlikely to have tissue residues above the US FDA tolerance or EU MRL following negative urine testing. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: October 12, 2020

2020 journal article

Sterility and concentration of liposomal bupivacaine single-use vial when used in a multiple-dose manner

VETERINARY SURGERY, 49(4), 772–777.

By: A. Carlson  n, E. Nixon n , M. Jacob n & K. Messenger n

MeSH headings : Anesthesia, Local / methods; Anesthesia, Local / veterinary; Anesthetics, Local / analysis; Anesthetics, Local / therapeutic use; Bupivacaine / analysis; Bupivacaine / therapeutic use; Drug Contamination; Drug Storage
TL;DR: Single-use liposomal bupivacaine liposome injectable suspension used in a multiple-dose fashion for 5 days yielded no bacterial growth and remained sterile for 5 days when aseptic technique was used. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 27, 2020

2016 journal article

Pharmacokinetics of C-14-ortho-phenylphenol following intravenous administration in pigs

JOURNAL OF APPLIED TOXICOLOGY, 37(4), 508–512.

By: E. Nixon n , J. Brooks n, P. Routh n, J. Chittenden * & R. Baynes n 

author keywords: pharmacokinetics; ortho-phenylphenol; intravenous dose; pig; biocide
MeSH headings : Administration, Intravenous; Animals; Area Under Curve; Biphenyl Compounds / administration & dosage; Biphenyl Compounds / pharmacokinetics; Disinfectants / pharmacokinetics; Feces / chemistry; Half-Life; Male; Sus scrofa; Swine; Tissue Distribution
TL;DR: Comparisons with other species suggest that 14C‐OPP clearance in pigs (2.48 ml h–1 kg–1) is less than that in humans and rats and that the kidneys play a crucial role in clearance with a large percentage of the dose being found in the urine. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 6, 2018

Education

Updated: July 27th, 2024 13:41

2017 - 2021

NC State University Raleigh, NC, US
Comparative Biomedical Sciences Graduate Program

2013 - 2017

University of Surrey Guildford, Surrey, GB
BSc Veterinary Biosciences (Hons)

Funding History

Funding history based on the linked ORCID record. Updated: February 17th, 2020 12:14

grant January 1, 2020 - January 1, 2022
Identifying practical pharmaceutical approaches to mitigate castration pain on commercial swine farms
American Veterinary Medical Foundation

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2025) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.