Erin M. Phelps

Works (1)

Updated: June 14th, 2023 22:25

2012 journal article

Structural transitions and oligomerization along polyalanine fibril formation pathways from computer simulations

Proteins, 80(6), 1582–1597.

By: E. Phelps n & C. Hall n 

MeSH headings : Amyloid / chemistry; Amyloid / metabolism; Molecular Dynamics Simulation; Peptides / chemistry; Peptides / metabolism; Protein Conformation; Temperature
TL;DR: The results of a computer simulation study of the aggregation kinetics of a large system of model peptides with particular focus on the formation of intermediates are presented, showing the rearrangement of amorphous aggregates into beta sheets is a critical and necessary step in the fibrillar formation pathway. (via Semantic Scholar)
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Added: August 6, 2018

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