Works (1)
Updated: July 5th, 2023 15:53
2008 journal article
X-LRT: A likelihood approach to estimate genetic risks and test association with X-linked markers using a case-parents design
GENETIC EPIDEMIOLOGY, 32(4), 370–380.
author keywords: sex linked; maximum-likelihood estimation; confidence interval; hypothesis test; family-based design
MeSH headings : Algorithms; Biometry; Computer Simulation; Confidence Intervals; Epidemiologic Methods; Female; Genes, X-Linked; Genetic Diseases, X-Linked / epidemiology; Genetic Diseases, X-Linked / genetics; Genetic Markers; Haplotypes; Humans; Likelihood Functions; Male; Models, Genetic; Monoamine Oxidase / genetics; Parents; Parkinson Disease / enzymology; Parkinson Disease / genetics; Penetrance; Risk Factors; Siblings
TL;DR:
A likelihood approach to estimate disease‐related marker relative risks and test genotype association using a case‐parents design and shows how efficiency with missing parental information can be improved with additional sibling genotype information.
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UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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