Eric Scott Land

Works (13)

Updated: February 6th, 2026 14:55

2024 article

Conserved plant transcriptional responses to microgravity from two consecutive spaceflight experiments

Land, E. S., Sheppard, J., Doherty, C. J., & Perera, I. Y. (2024, January 8). Frontiers in Plant Science, Vol. 14.

By: E. Land n , J. Sheppard  n, C. Doherty n  & I. Perera n 

author keywords: transcriptional profiling; adaptation to spaceflight; Arabidopsis; microgravity (mu g); plants
topics (OpenAlex): Polar Research and Ecology; Light effects on plants; Plant Molecular Biology Research
TL;DR: Two separate spaceflight experiments conducted on the International Space Station uncovered microgravity unique transcriptional changes and highlight the validity and importance of an onboard 1 g control. (via Semantic Scholar)
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2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: February 1, 2024

2023 article

Arabidopsis telomerase takes off by uncoupling enzyme activity from telomere length maintenance in space

Barcenilla, B. B., Meyers, A. D., Castillo-González, C., Young, P., Min, J.-H., Song, J., … Shippen, D. E. (2023, November 29). Nature Communications, Vol. 14.

By: B. Barcenilla *, A. Meyers *, C. Castillo-González *, P. Young *, J. Min *, J. Song *, C. Phadke*, E. Land n  ...

MeSH headings : Telomere Homeostasis; Arabidopsis / metabolism; Telomerase / genetics; Telomerase / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Telomere-Binding Proteins / metabolism; Telomere / genetics; Telomere / metabolism; Plants / metabolism
topics (OpenAlex): Telomeres, Telomerase, and Senescence; Spaceflight effects on biology; Genetics, Aging, and Longevity in Model Organisms
TL;DR: No changes in telomere length in space-flown Arabidopsis seedlings are observed, despite a dramatic increase in telomerase activity (up to 150-fold in roots), as well as elevated genome oxidation, and it is proposed that genome oxidation is inversely correlated with telomersase activity levels. (via Semantic Scholar)
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Sources: ORCID, Web Of Science, NC State University Libraries
Added: November 30, 2023

2023 article

Bridging the gap: parallel profiling of ribosome associated and total RNA species can identify transcriptional regulatory mechanisms of plants in spaceflight

Land, E. S., Canaday, E., Meyers, A., Wyatt, S., & Perera, I. Y. (2023, August 28). Journal of Plant Interactions, Vol. 18.

By: E. Land n , E. Canaday *, A. Meyers *, S. Wyatt * & I. Perera n 

author keywords: Spaceflight; transcriptomics; translatomics; TRAP; Arabidopsis thaliana
topics (OpenAlex): Plant Molecular Biology Research; Chromosomal and Genetic Variations; Photosynthetic Processes and Mechanisms
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: August 29, 2023

2022 article

Polyethersulfone (PES) Membrane on Agar Plates as a Plant Growth Platform for Spaceflight

Meyers, A., Land, E., Perera, I., Canaday, E., & Wyatt, S. E. (2022, January 1). Gravitational and Space Research.

By: A. Meyers *, E. Land n , I. Perera  n, E. Canaday * & S. Wyatt *

topics (OpenAlex): Light effects on plants; Magnetic and Electromagnetic Effects; Spaceflight effects on biology
TL;DR: Protocols were developed for using an agar-polyethersulfone (PES) membrane platform for seedling growth that allowed for seedlings germination and growth aboard the ISS and rapid freezing to provide intact seedlings for dissection and extraction of high-quality DNA, RNA, and protein. (via Semantic Scholar)
Source: ORCID
Added: December 4, 2023

2021 article

A Role for Inositol Pyrophosphates in the Metabolic Adaptations to Low Phosphate in Arabidopsis

Land, E. S., Cridland, C. A., Craige, B., Dye, A., Hildreth, S. B., Helm, R. F., … Perera, I. Y. (2021, September 4). Metabolites, Vol. 11, p. 601.

By: E. Land n , C. Cridland *, B. Craige *, A. Dye n , S. Hildreth*, R. Helm *, G. Gillaspy *, I. Perera n 

author keywords: inositol pyrophosphates; phosphate starvation response; phosphate homeostasis; lipid remodeling; AtVIP1; AtVIP2
topics (OpenAlex): Plant nutrient uptake and metabolism; Plant Micronutrient Interactions and Effects; Phytase and its Applications
TL;DR: Evidence that both local and systemic responses to phosphate limitation are dampened in the vip1/vip2 mutants as compared to wild-type plants is presented, providing insight on the nexus between inositol phosphates and pyrophosphates involved in complex regulatory mechanisms underpinning phosphate homeostasis in plants. (via Semantic Scholar)
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2. Zero Hunger (Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 8, 2021

2021 article

Lipid remodeling in response to low phosphate is modulated by inositol pyrophosphates

Cridland, C., Land, E., Williams, P., Hildreth, S., Helm, R., Perera, I., & Gillaspy, G. (2021, May 1). The FASEB Journal.

By: C. Cridland *, E. Land n , P. Williams*, S. Hildreth*, R. Helm *, I. Perera  n, G. Gillaspy *

topics (OpenAlex): Plant nutrient uptake and metabolism; Lipid metabolism and biosynthesis; Phytase and its Applications
Source: ORCID
Added: December 4, 2023

2021 article

The Circadian-clock Regulates the Arabidopsis Gravitropic Response

Tolsma, J. S., Ryan, K. T., Torres, J. J., Richards, J. T., Richardson, Z., Land, E. S., … Doherty, C. J. (2021, January 1). Gravitational and Space Research.

By: J. Tolsma  n, K. Ryan  n, J. Torres *, J. Richards*, Z. Richardson n, E. Land n , I. Perera n , C. Doherty n 

topics (OpenAlex): Plant Molecular Biology Research; Magnetic and Electromagnetic Effects; Light effects on plants
TL;DR: Gravitropic responses were disrupted in plants with disrupted circadian clocks, including plants overexpressing Circadian-clock Associated 1 (CCA1) and elf3-2, in the reorientation assay and on a 2D clinostat suggesting the variation is circadian-regulated. (via Semantic Scholar)
Source: ORCID
Added: January 6, 2022

2021 article

Uncovering Transcriptional Responses to Fractional Gravity in Arabidopsis Roots

Sheppard, J., Land, E. S., Toennisson, T. A., Doherty, C. J., & Perera, I. Y. (2021, September 24). Life, Vol. 10.

By: J. Sheppard  n, E. Land n , T. Toennisson n , C. Doherty n  & I. Perera n 

author keywords: spaceflight; fractional gravity; RNA-seq; Arabidopsis; gene expression; heat shock proteins
topics (OpenAlex): Magnetic and Electromagnetic Effects; Light effects on plants; Plant Molecular Biology Research
TL;DR: A subset of genes whose expression correlates with changes in fractional g include those encoding transcription factors, defense, and cell wall-related proteins and heat shock proteins, which are likely to be responsive to gravity changes. (via Semantic Scholar)
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UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 28, 2021

2019 article

Inositol Pyrophosphates and Phosphate Sensing in Plants

Gillaspy, G., Adepoju, O., Land, E., Williams, S. P., Donahue, J., Cridland, C., … Perera, I. (2019, April 1). The FASEB Journal.

By: G. Gillaspy *, O. Adepoju*, E. Land n , S. Williams*, J. Donahue*, C. Cridland *, C. Freed *, I. Perera  n

topics (OpenAlex): Phytase and its Applications; Plant nutrient uptake and metabolism; Pineapple and bromelain studies
TL;DR: The results support a model in which InsP7 and InsP8 function to turn off the PSR in plants, and genetic mutants key for understanding inositol kinase gene function in plants are described. (via Semantic Scholar)
Source: ORCID
Added: December 4, 2023

2019 article

Inositol Trisphosphate Kinase and Diphosphoinositol Pentakisphosphate Kinase Enzymes Constitute the Inositol Pyrophosphate Synthesis Pathway in Plants

Adepoju, O., Williams, S. P., Craige, B., Cridland, C. A., Sharpe, A. K., Brown, A. M., … Gillaspy, G. E. (2019, August 5).

By: O. Adepoju*, S. Williams*, B. Craige *, C. Cridland *, A. Sharpe*, A. Brown *, E. Land n , I. Perera  n ...

topics (OpenAlex): Phytase and its Applications; Pineapple and bromelain studies; Cellular transport and secretion
TL;DR: A molecular basis for understanding how plants synthesize PP-InsPs is defined which is crucial for determining the roles of these signaling molecules in processes such as Pi sensing and to help design future strategies to increase phosphate efficiency in plants. (via Semantic Scholar)
Source: ORCID
Added: February 1, 2024

2015 chapter

Methods for RNA Profiling of Gravi-Responding Plant Tissues

Dalal, J., Land, E., Vasani, N., He, L., Smith, C., Rodriguez-Welsh, M., … Sederoff, H. (2015, January 1). Methods in Molecular Biology.

By: J. Dalal  n, E. Land n , N. Vasani n, L. He n, C. Smith  n, M. Rodriguez-Welsh n, I. Perera n , H. Sederoff n 

Contributors: J. Dalal  n, E. Land n , N. Vasani n, L. He n, C. Smith  n, M. Rodriguez-Welsh n, I. Perera n , H. Sederoff n 

author keywords: RNA; Transcript; Transcriptome; Sequencing; PCR; RNAseq; sRNA; miRNA
MeSH headings : Gene Expression Profiling / methods; Gene Expression Regulation, Plant; Gravity Sensing / genetics; Oligonucleotide Array Sequence Analysis / methods; RNA / genetics; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Seeds / genetics; Seeds / growth & development; Transcriptome / genetics
topics (OpenAlex): Banana Cultivation and Research; Nuts composition and effects; Plant and Fungal Interactions Research
TL;DR: The current and most widely used methods to profile the changes in an entire transcriptome by high-throughput sequencing of RNA fractions (RNAseq) and single gene transcript analysis using real-time quantitative reverse-transcriptase polymerase chain reaction (qRT-PCR) are described. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, Crossref, ORCID
Added: August 6, 2018

2014 journal article

Two inositol hexakisphosphate kinases drive inositol pyrophosphate synthesis in plants

The Plant Journal, 80(4), 642–653.

By: M. Desai n, P. Rangarajan*, J. Donahue*, S. Williams*, E. Land n , M. Mandal *, B. Phillippy n, I. Perera n , V. Raboy *, G. Gillaspy *

author keywords: Arabidopsis thaliana; At3g01310; At5g15070; inositol pyrophosphate; inositol kinase; InsP(6)
MeSH headings : Arabidopsis / genetics; Arabidopsis / metabolism; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Chromatography, High Pressure Liquid; Genetic Complementation Test; Inositol Phosphates / metabolism; Mutation; Phosphotransferases (Alcohol Group Acceptor) / genetics; Phosphotransferases (Alcohol Group Acceptor) / metabolism; Phosphotransferases (Phosphate Group Acceptor) / genetics; Phosphotransferases (Phosphate Group Acceptor) / metabolism; Phylogeny; Plant Proteins / genetics; Plant Proteins / metabolism; Seeds / metabolism; Transcription Factors, General / genetics; Transcription Factors, General / metabolism; Yeasts / genetics; Zea mays / genetics; Zea mays / metabolism
topics (OpenAlex): Phytase and its Applications; Legume Nitrogen Fixing Symbiosis; Enzyme Production and Characterization
TL;DR: It is reported that Arabidopsis and maize InsP6 transporter mutants have elevated levels of inositol pyrophosphates in their seed, providing unequivocal identification of their presence in plant tissues and it is shown that plant seeds store a little over 1% of their inositl phosphate pool as InsP7 and InsP8. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018

2012 article

A role for lipid‐mediated signaling in plant gravitropism

Smith, C. M., Desai, M., Land, E. S., & Perera, I. Y. (2012, December 21). American Journal of Botany, Vol. 100, pp. 153–160.

By: C. Smith  n, M. Desai n, E. Land n  & I. Perera n 

author keywords: auxin; calcium; gravitropism; InsP(3); lipid signaling
MeSH headings : Gravitropism / physiology; Indoleacetic Acids / metabolism; Lipid Metabolism; Phosphatidylinositols / metabolism; Plants / metabolism; Signal Transduction
topics (OpenAlex): Plant Molecular Biology Research; Photosynthetic Processes and Mechanisms; Plant Reproductive Biology
TL;DR: This thesis is that membrane lipids and lipid-mediated signaling pathways play critical roles in the initial signaling and in the establishment of polarity in Gravitropism. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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