Works (115)

Updated: May 25th, 2023 05:00

2023 article

A tiered testing strategy based on in vitro phenotypic and transcriptomic data for selecting representative petroleum UVCBs for toxicity evaluation in vivo

Tsai, H.-H. D., House, J. S., Wright, F. A., Chiu, W. A., & Rusyn, I. (2023, April 20). TOXICOLOGICAL SCIENCES.

By: H. Tsai*, J. House*, F. Wright, W. Chiu* & I. Rusyn*

author keywords: transcriptomic; petroleum; grouping; dose-response; HTTr; NAMs
Source: Web Of Science
Added: May 22, 2023

2022 journal article

A Population-Based Human In Vitro Approach to Quantify Inter-Individual Variability in Responses to Chemical Mixtures

TOXICS, 10(8).

By: L. Ford*, S. Jang*, Z. Chen*, Y. Zhou, P. Gallins, F. Wright, W. Chiu*, I. Rusyn*

author keywords: population-wide; inter-individual variability; toxicodynamics; chemical mixtures; defined mixtures; human health risk assessment; uncertainty factors; genome-wide association study
Sources: Web Of Science, ORCID
Added: August 2, 2022

2022 journal article

A resource for integrated genomic analysis of the human liver

SCIENTIFIC REPORTS, 12(1).

By: Y. Zhou, P. Gallins, A. Etheridge*, D. Jima, E. Scholl, F. Wright, F. Innocenti*

Sources: Web Of Science, ORCID
Added: September 8, 2022

2022 journal article

Characterization of compositional variability in petroleum substances

FUEL, 317.

By: A. Roman-Hubers, A. Cordova, A. Rohde, W. Chiu, T. McDonald, F. Wright, J. Dodds, E. Baker, I. Rusyn

author keywords: UVCB; Registration; Variability; IMS-MS
Sources: Web Of Science, ORCID
Added: May 10, 2022

2022 journal article

Characterization of population variability of 1,3-butadiene derived protein adducts in humans and mice

REGULATORY TOXICOLOGY AND PHARMACOLOGY, 132.

By: G. Boysen*, I. Rusyn*, W. Chiu* & F. Wright

Source: Web Of Science
Added: June 6, 2022

2022 journal article

Correlation Analysis of Variables From the Atherosclerosis Risk in Communities Study

FRONTIERS IN PHARMACOLOGY, 13.

By: M. Mandal*, J. Levy*, C. Ives*, S. Hwang*, Y. Zhou n, A. Motsinger-Reif, H. Pan*, W. Huggins* ...

author keywords: cluster analysis; systems biology; meta-analysis as topic; ARIC; cardiovascular disease
Source: Web Of Science
Added: August 8, 2022

2022 article

Fast Multivariate Probit Estimation via a Two-Stage Composite Likelihood

Ting, B., Wright, F., & Zhou, Y.-H. (2022, February 15). STATISTICS IN BIOSCIENCES, Vol. 2.

By: B. Ting, F. Wright & Y. Zhou

author keywords: Composite; Likelihood; Multivariate; Probit; Two-stage; Two-step
Sources: Web Of Science, ORCID
Added: February 15, 2022

2022 article

Genomic map of candidate human imprint control regions: the imprintome

Jima, D. D., Skaar, D. A., Planchart, A., Motsinger-Reif, A., Cevik, S. E., Park, S. S., … Hoyo, C. (2022, June 25). EPIGENETICS, Vol. 6.

By: D. Jima, D. Skaar, A. Planchart, A. Motsinger-Reif, S. Cevik n, S. Park, M. Cowley, F. Wright ...

author keywords: Epigenetics; genomic imprinting; foetal origins; whole genome; methylation; imprint control regions
Sources: Web Of Science, ORCID
Added: July 11, 2022

2022 journal article

Grouping of UVCB Substances with Dose-Response Transcriptomics Data from Human Cell-Based Assays

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 39(3), 388–404.

By: J. House, F. Grimm*, W. Klaren*, A. Dalzell*, S. Kuchi*, S. Zhang*, K. Lenz*, P. Boogaard ...

Sources: Web Of Science, ORCID
Added: August 29, 2022

2022 journal article

Identification and single-base gene-editing functional validation of a cis-EPO variant as a genetic predictor for EPO-increasing therapies

AMERICAN JOURNAL OF HUMAN GENETICS, 109(9), 1638–1652.

By: C. Harlow, J. Gandawijaya*, R. Bamford*, E. Martin*, A. Wood*, P. Most*, T. Tanaka*, H. Leonard* ...

Source: Web Of Science
Added: November 21, 2022

2022 journal article

Leveraging TOPMed imputation server and constructing a cohort-specific imputation reference panel to enhance genotype imputation among cystic fibrosis patients

HUMAN GENETICS AND GENOMICS ADVANCES, 3(2).

By: Q. Sun*, W. Liu*, J. Rosen*, L. Huang*, R. Pace*, H. Dang*, P. Gallins, E. Blue ...

Sources: Web Of Science, ORCID
Added: May 10, 2022

2022 journal article

MagicalRsq: Machine-learning-based genotype imputation quality calibration

AMERICAN JOURNAL OF HUMAN GENETICS, 109(11), 1986–1997.

By: Q. Sun*, Y. Yang, J. Rosen, M. Jiang, J. Chen, W. Liu, J. Wen, L. Raffield ...

Sources: Web Of Science, ORCID
Added: January 17, 2023

2022 journal article

Model systems and organisms for addressing inter- and intra-species variability in risk assessment

REGULATORY TOXICOLOGY AND PHARMACOLOGY, 132.

By: I. Rusyn, W. Chiu & F. Wright

Source: Web Of Science
Added: August 15, 2022

2022 journal article

Pleiotropic modifiers of age-related diabetes and neonatal intestinal obstruction in cystic fibrosis

AMERICAN JOURNAL OF HUMAN GENETICS, 109(10), 1894–1908.

By: M. Aksit*, H. Ling, R. Pace, K. Raraigh, F. Onchiri, A. Faino, K. Pagel, E. Pugh ...

Sources: Web Of Science, ORCID
Added: November 21, 2022

2022 journal article

Spatial and Temporal Analysis of Impacts of Hurricane Florence on Criteria Air Pollutants and Air Toxics in Eastern North Carolina

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 19(3).

By: S. Bhandari*, G. Casillas*, N. Aly*, R. Zhu*, G. Newman*, F. Wright, A. Miller*, G. Adler*, I. Rusyn*, W. Chiu*

author keywords: air pollution; geospatial analyses; criteria pollutants; volatile organic compounds
Source: Web Of Science
Added: March 7, 2022

2022 article

TwinEQTL: ultrafast and powerful association analysis for eQTL and GWAS in twin studies

Xia, K., Shabalin, A. A., Yin, Z., Chung, W., Sullivan, P. F., Wright, F. A., … Zou, F. (2022, June 11). GENETICS.

author keywords: Twin; eQTL; GWAS
Source: Web Of Science
Added: July 11, 2022

2021 journal article

Application of Edible Montmorillonite Clays for the Adsorption and Detoxification of Microcystin

ACS APPLIED BIO MATERIALS, 4(9), 7254–7265.

By: M. Wang*, K. Rivenbark*, J. Gong, F. Wright & T. Phillips*

author keywords: adsorption isotherm; Hydra vulgaris; Lemna minor; Caenorhabditis elegans; molecular model; dietary sorbent
Sources: Web Of Science, ORCID
Added: October 12, 2021

2021 journal article

Data Processing Workflow to Identify Structurally Related Compounds in Petroleum Substances Using Ion Mobility Spectrometry-Mass Spectrometry

ENERGY & FUELS, 35(13), 10529–10539.

By: A. Roman-Hubers, A. Cordova, N. Aly, T. McDonald, D. Lloyd, F. Wright, E. Baker, W. Chiu, I. Rusyn

Sources: Web Of Science, ORCID
Added: July 26, 2021

2021 journal article

Environmental impacts of Hurricane Florence flooding in eastern North Carolina: temporal analysis of contaminant distribution and potential human health risks

JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, 31(5), 810–822.

By: N. Aly*, G. Casillas*, Y. Luo*, T. McDonald*, T. Wade*, R. Zhu*, G. Newman*, D. Lloyd ...

author keywords: Disaster research response; Superfund; Chemical contaminants
Source: Web Of Science
Added: May 24, 2021

2021 journal article

Grouping of UVCB Substances with New Approach Methodologies (NAMs) Data

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 38(1), 123–137.

By: J. House, F. Grimm*, W. Klaren*, A. Dalzell*, S. Kuchi*, S. Zhang*, K. Lenz*, P. Boogaard* ...

Sources: Web Of Science, ORCID
Added: March 15, 2021

2021 journal article

Intra- and Inter-Species Variability in Urinary N7-(1-Hydroxy-3-buten-2-yl)guanine Adducts Following Inhalation Exposure to 1,3-Butadiene

CHEMICAL RESEARCH IN TOXICOLOGY, 34(11), 2375–2383.

By: L. Erber*, S. Goodman*, F. Wright, W. Chiu*, N. Tretyakova* & I. Rusyn*

Source: Web Of Science
Added: November 29, 2021

2021 journal article

Potential Human Health Hazard of Post-Hurricane Harvey Sediments in Galveston Bay and Houston Ship Channel: A Case Study of Using In Vitro Bioactivity Data to Inform Risk Management Decisions

INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH, 18(24).

By: Z. Chen*, S. Jang*, J. Kaihatu*, Y. Zhou, F. Wright, W. Chiu*, I. Rusyn*

author keywords: new approach methods (NAMs); environmental mixtures; disaster research
Sources: Web Of Science, ORCID
Added: December 20, 2021

2021 journal article

Relationships between constituents of energy drinks and beating parameters in human induced pluripotent stem cell (iPSC)-Derived cardiomyocytes

FOOD AND CHEMICAL TOXICOLOGY, 149.

By: Y. Luo*, Z. Chen*, A. Blanchette*, Y. Zhou, F. Wright, E. Baker, W. Chiu*, I. Rusyn*

author keywords: Cardiovascular; Heart rate; QT interval; Theophylline; Adenine; Azelate
Sources: Web Of Science, ORCID
Added: February 4, 2021

2021 journal article

Risk Characterization of Environmental Samples Using In Vitro Bioactivity and Polycyclic Aromatic Hydrocarbon Concentrations Data

TOXICOLOGICAL SCIENCES, 179(1), 108–120.

By: Z. Chen*, D. Lloyd, Y. Zhou n, W. Chiu*, F. Wright & I. Rusyn*

author keywords: polycyclic aromatic hydrocarbons; mixtures toxicology; in vitro models; iPSC; humanized models; human risk assessment; risk assessment; new approach methods; bioactivity; spatial analysis
Source: Web Of Science
Added: March 15, 2021

2021 personal communication

The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning

Marvel, S. W., House, J. S., Wheeler, M., Song, K., Zhou, Y.-H., Wright, F. A., … Reif, D. M. (2021, January).

By: S. Marvel, J. House, M. Wheeler*, K. Song, Y. Zhou, F. Wright, W. Chiu*, I. Rusyn*, A. Motsinger-Reif, D. Reif

Sources: Web Of Science, ORCID
Added: March 22, 2021

2020 journal article

A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex-Biased Phenotypes

CLINICAL PHARMACOLOGY & THERAPEUTICS, 107(6), 1383–1393.

By: A. Etheridge*, P. Gallins, D. Jima, K. Broadaway*, M. Ratain*, E. Schuetz*, E. Schadt*, A. Schroder* ...

Sources: Web Of Science, ORCID
Added: February 10, 2020

2020 journal article

Classification of estrogenic compounds by coupling high content analysis and machine learning algorithms

PLOS COMPUTATIONAL BIOLOGY, 16(9).

By: R. Mukherjee*, B. Beykal*, A. Szafran*, M. Onel*, F. Stossi*, M. Mancini*, D. Lloyd, F. Wright ...

Source: Web Of Science
Added: October 26, 2020

2020 journal article

Low-Dose Silver Nanoparticle Surface Chemistry and Temporal Effects on Gene Expression in Human Liver Cells

SMALL, 16(21).

By: J. House, E. Bouzos*, K. Fahy*, V. Francisco*, D. Lloyd, F. Wright, A. Motsinger-Reif, P. Asuri*, K. Wheeler*

author keywords: nanotoxicity; silver nanoparticles; transcriptomics
Sources: Web Of Science, ORCID
Added: April 14, 2020

2020 personal communication

Questioning Existing Cancer Hazard Evaluation Standards in the Name of Statistics

Rusyn, I., Chiu, W. A., & Wright, F. A. (2020, October).

By: I. Rusyn*, W. Chiu* & F. Wright

Source: Web Of Science
Added: December 14, 2020

2020 journal article

Rapid Hazard Characterization of Environmental Chemicals Using a Compendium of Human Cell Lines from Different Organs

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 37(4), 623–638.

By: Z. Chen*, Y. Liu, F. Wright, W. Chiu & I. Rusyn

Source: Web Of Science
Added: February 15, 2021

2020 journal article

Systematic Comparisons for Composition Profiles, Taxonomic Levels, and Machine Learning Methods for Microbiome-Based Disease Prediction

FRONTIERS IN MOLECULAR BIOSCIENCES, 7.

By: K. Song, F. Wright & Y. Zhou

author keywords: phenotype prediction; machine learning method; k-mers; operational taxonomic unit (OTU); amplicon sequence variant (ASV); phylogenetic analysis
Sources: Web Of Science, ORCID
Added: January 19, 2021

2020 journal article

The GTEx Consortium atlas of genetic regulatory effects across human tissues

SCIENCE, 369(6509), 1318–1330.

By: F. Aguet, A. Barbeira, R. Bonazzola, A. Brown, S. Castel, B. Jo, S. Kasela, S. Kim-Hellmuth* ...

Source: Web Of Science
Added: November 16, 2020

2019 article

Development of the Texas A&M Superfund Research Program Computational Platform for Data Integration, Visualization, and Analysis

29TH EUROPEAN SYMPOSIUM ON COMPUTER AIDED PROCESS ENGINEERING, PT A, Vol. 46, pp. 967–972.

author keywords: Data analytics; data integration; statistical analysis; collaborative networks
Source: Web Of Science
Added: November 25, 2019

2019 journal article

Grouping of complex substances using analytical chemistry data: A framework for quantitative evaluation and visualization

PLOS ONE, 14(10).

By: M. Onel*, B. Beykal*, K. Ferguson*, W. Chiu*, T. McDonald*, L. Zhou*, J. House, F. Wright ...

Sources: Web Of Science, ORCID
Added: June 1, 2020

2019 journal article

Multi-dimensional in vitro bioactivity profiling for grouping of glycol ethers

REGULATORY TOXICOLOGY AND PHARMACOLOGY, 101, 91–102.

By: F. Grimm*, J. House, M. Wilson*, O. Sirenko*, Y. Iwata*, F. Wright, N. Ball*, I. Rusyn*

author keywords: New assessment methodologies; Glycol ethers; In vitro; ToxPi; Read-across; Safety assessment
Sources: Web Of Science, ORCID
Added: April 22, 2019

2019 journal article

Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse

CHEMICAL RESEARCH IN TOXICOLOGY, 32(5), 887–898.

By: L. Lewis*, B. Borowa-Mazgaj*, A. Conti*, G. Chappell*, Y. Luo*, W. Bodnar*, K. Konganti*, F. Wright ...

Source: Web Of Science
Added: June 17, 2019

2019 journal article

Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Population-Based Analysis of Toxicokinetics and Kidney Toxicodynamics of Tetrachloroethylene

ENVIRONMENTAL HEALTH PERSPECTIVES, 127(6).

By: Y. Luo*, J. Cichocki*, N. Hsieh*, L. Lewis*, F. Wright, D. Threadgill, W. Chiu*, I. Rusyn*

Source: Web Of Science
Added: July 29, 2019

2018 journal article

A Human Population-Based Organotypic In Vitro Model for Cardiotoxicity Screening

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 35(4), 441–452.

By: F. Grimm*, A. Blanchette*, J. House, K. Ferguson*, N. Hsieh*, C. Dalaijamts*, A. Wright*, B. Anson* ...

Sources: Web Of Science, ORCID
Added: December 10, 2018

2018 journal article

A common allele in FGF21 associated with sugar intake is associated with body shape, lower total body-fat percentage, and higher blood pressure

Cell Reports, 23(2), 327–336.

By: T. Frayling, R. Beaumont, S. Jones, H. Yaghootkar, M. Tuke, K. Ruth, F. Casanova, B. West ...

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Airway mucosal host defense is key to genomic regulation of cystic fibrosis lung disease severity

American Journal of Respiratory and Critical Care Medicine, 197(1), 79–93.

By: D. Polineni, H. Dang, P. Gallins, L. Jones, R. Pace, J. Stonebraker, L. Commander, J. Krenicky ...

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

An empirical Bayes approach for multiple tissue eQTL analysis

Biostatistics (Oxford, England), 19(3), 391–406.

By: G. Li*, A. Shabalin*, I. Rusyn*, F. Wright & A. Nobel*

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Computation of ancestry scores with mixed families and unrelated individuals

BIOMETRICS, 74(1), 155–164.

By: Y. Zhou, J. Marron* & F. Wright

author keywords: Genetic association; Population stratification; Principal components
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Estimation of cis-eQTL effect sizes using a log of linear model

BIOMETRICS, 74(2), 616–625.

By: J. Palowitch*, A. Shabalin*, Y. Zhou, A. Nobel* & F. Wright

author keywords: eQTL analyses; EQTL effect size; Multiple testing; Nonlinear regression
Sources: Web Of Science, ORCID
Added: October 16, 2018

2018 journal article

HT-eQTL: integrative expression quantitative trait loci analysis in a large number of human tissues

BMC Bioinformatics, 19.

By: G. Li, D. Jima, F. Wright & A. Nobel

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Periconceptional maternal mediterranean diet is associated with favorable offspring behaviors and altered CpG methylation of imprinted genes

Frontiers in Cell and Developmental Biology, 6(SEP), 107.

By: J. House, M. Mendez*, R. Maguire, S. Gonzalez-Nahm*, Z. Huang*, J. Daniels*, S. Murphy*, B. Fuemmeler*, F. Wright, C. Hoyo

Sources: NC State University Libraries, ORCID
Added: January 21, 2019

2018 journal article

Polyphasic characterization of four soil-derived phenanthrene-degrading Acidovorax strains and proposal of Acidovorax carolinensis sp nov.

SYSTEMATIC AND APPLIED MICROBIOLOGY, 41(5), 460–472.

author keywords: Acidovorax; Phenanthrene; Polycyclic aromatic hydrocarbons
Source: Web Of Science
Added: October 16, 2018

2018 journal article

Population-based dose-response analysis of liver transcriptional response to trichloroethylene in mouse

MAMMALIAN GENOME, 29(1-2), 168–181.

By: A. Venkatratnam*, J. House, K. Konganti*, C. McKenney n, D. Threadgill*, W. Chiu*, D. Aylor, F. Wright, I. Rusyn*

Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models

BMC Bioinformatics, 19.

By: S. Marvel, K. To, F. Grimm, F. Wright, I. Rusyn & D. Reif

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

A Pipeline for high-throughput concentration response modeling of gene expression for toxicogenomics

Frontiers in Genetics, 8.

By: J. House, F. Grimm, D. Jima, Y. Zhou, I. Rusyn & F. Wright

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

A procedure to detect general association based on concentration of ranks

Stat, 6(1), 88–101.

By: P. Rudra, Y. Zhou & F. Wright

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

A tiered, Bayesian approach to estimating population variability for regulatory decision-making

Altex-Alternatives to Animal Experimentation, 34(3), 377–388.

By: W. Chiu, F. Wright & I. Rusyn

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Adrenal-derived stress hormones modulate ozone-induced lung injury and inflammation

TOXICOLOGY AND APPLIED PHARMACOLOGY, 329, 249–258.

By: A. Henriquez*, J. House, D. Miller*, S. Snow*, A. Fisher*, H. Ren*, M. Schladweiler*, A. Ledbetter*, F. Wright, U. Kodavanti*

author keywords: Ozone; Lung; Stress hormones; Adrenalectomy; RNAseq
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

An improved and explicit surrogate variable analysis procedure by coefficient adjustment

BIOMETRIKA, 104(2), 303–316.

By: S. Lee*, W. Sun*, F. Wright & F. Zou*

author keywords: Batch effect; High-dimensional data; Principal component analysis; Surrogate variable analysis
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Conditional eQTL analysis reveals allelic heterogeneity of gene expression

HUMAN MOLECULAR GENETICS, 26(8), 1444–1451.

By: R. Jansen*, J. Hottenga*, M. Nivard*, A. Abdellaoui*, B. Laport*, E. Geus*, F. Wright, B. Penninx*, D. Boomsma*

Source: Web Of Science
Added: August 6, 2018

2017 journal article

Dynamic landscape and regulation of RNA editing in mammals

Nature, 550(7675), 249–254.

By: M. Tan*, Q. Li*, R. Shanmugam*, R. Piskol*, J. Kohler*, A. Young*, K. Liu*, R. Zhang* ...

Sources: Crossref, ORCID
Added: January 25, 2020

2017 journal article

Editor's Highlight: Collaborative Cross Mouse Population Enables Refinements to Characterization of the Variability in Toxicokinetics of Trichloroethylene and Provides Genetic Evidence for the Role of PPAR Pathway in Its Oxidative Metabolism

TOXICOLOGICAL SCIENCES, 158(1), 48–62.

By: A. Venkatratnam*, S. Furuya*, O. Kosyk*, A. Gold*, W. Bodnar*, K. Konganti*, D. Threadgill*, K. Gillespie n ...

author keywords: population; trichloroethylene; mouse
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues

AMERICAN JOURNAL OF HUMAN GENETICS, 100(4), 605–616.

By: X. Liu*, H. Finucane*, A. Gusev*, G. Bhatia*, S. Gazal*, L. O'Connor*, B. Bulik-Sullivan*, F. Wright ...

Source: Web Of Science
Added: August 6, 2018

2017 journal article

Genetic effects on gene expression across human tissues

Nature, 550(7675), 204-.

By: F. Aguet, A. Brown, S. Castel, J. Davis, Y. He, B. Jo, P. Mohammadi, Y. Park ...

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Genetic effects on gene expression across human tissues

Nature, 550(7675), 204–213.

By: F. Aguet, A. Brown*, S. Castel, J. Davis, Y. He*, B. Jo, P. Mohammadi, Y. Park ...

Ed(s): A. Battle*, C. Brown*, B. Engelhardt* & S. Montgomery*

Sources: Crossref, ORCID
Added: December 19, 2020

2017 journal article

Landscape of X chromosome inactivation across human tissues

Nature, 550(7675), 244–248.

By: T. Tukiainen*, A. Villani*, A. Yen*, M. Rivas*, J. Marshall*, R. Satija*, M. Aguirre*, L. Gauthier* ...

Source: Crossref
Added: December 19, 2020

2017 journal article

The impact of rare variation on gene expression across tissues

Nature, 550(7675), 239–243.

By: X. Li*, Y. Kim*, E. Tsang*, J. Davis*, F. Damani*, C. Chiang*, G. Hess*, Z. Zappala* ...

Sources: Crossref, ORCID
Added: January 25, 2020

2016 journal article

A chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives

GREEN CHEMISTRY, 18(16), 4407–4419.

By: F. Grimm*, Y. Iwata*, O. Sirenko*, G. Chappell*, F. Wright, D. Reif, J. Braisted*, D. Gerhold* ...

Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Erratum: Corrigendum: Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

Scientific Reports, 6(1), 19384.

By: J. Yang, T. Huang, F. Petralia, Q. Long, B. Zhang, C. Argmann, Y. Zhao, C. Mobbs ...

Source: Crossref
Added: January 4, 2021

2016 journal article

Gene expression in major depressive disorder

Molecular Psychiatry, 21(3), 339–347.

By: R. Jansen, B. Penninx, V. Madar, K. Xia, Y. Milaneschi, J. Hottenga, A. Hammerschlag, A. Beekman ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Homologous recombination and translesion DNA synthesis play critical roles on tolerating DNA damage caused by trace levels of hexavalent chromium

PLoS One, 11(12).

By: X. Tian, K. Patel, J. Ridpath, Y. Chen, Y. Zhou, D. Neo, J. Clement, M. Takata ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Integrative approaches for large-scale transcriptome-wide association studies

Nature Genetics, 48(3), 245–252.

By: A. Gusev, A. Ko, H. Shi, G. Bhatia, W. Chung, B. Penninx, R. Jansen, E. Geus ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Integrative approaches for large-scale transcriptome-wide association studies

Nature Genetics, 48(3), 245–252.

By: A. Gusev*, A. Ko*, H. Shi*, G. Bhatia*, W. Chung*, B. Penninx*, R. Jansen*, E. de Geus* ...

Source: Crossref
Added: February 24, 2020

2016 conference paper

Poster: risk-based attack surface approximation

Symposium and Bootcamp on the Science of Security, 121–123.

By: C. Theisen & L. Williams

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

The projack: a resampling approach to correct for ranking bias in high-throughput studies

Biostatistics (Oxford, England), 17(1), 54–64.

By: Y. Zhou & F. Wright

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Consistent testing for recurrent genomic aberrations

BIOMETRIKA, 102(4), 783–796.

By: V. Walter*, F. Wright & A. Nobel

author keywords: Consistency; DNA copy number; DNA methylation; Genome-wide association study; Hypothesis testing
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Erratum: Gene expression in major depressive disorder

Molecular Psychiatry, 21(3), 444–444.

By: R. Jansen, B. Penninx*, V. Madar, K. Xia, Y. Milaneschi*, J. Hottenga, A. Hammerschlag*, A. Beekman* ...

Source: Crossref
Added: August 28, 2020

2015 journal article

Erratum: Prediction of human population responses to toxic compounds by a collaborative competition

Nature Biotechnology, 33(10), 1109–1109.

By: F. Eduati, L. Mangravite, T. Wang*, H. Tang, J. Bare, R. Huang, T. Norman, M. Kellen ...

Source: Crossref
Added: February 24, 2020

2015 journal article

Gene Expression in Transformed Lymphocytes Reveals Variation in Endomembrane and HLA Pathways Modifying Cystic Fibrosis Pulmonary Phenotypes

The American Journal of Human Genetics, 96(2), 318–328.

By: W. O’Neal*, P. Gallins*, R. Pace*, H. Dang*, W. Wolf*, L. Jones*, X. Guo*, Y. Zhou ...

Sources: Crossref, NC State University Libraries
Added: August 6, 2018

2015 journal article

Gene expression in major depressive disorder

Molecular Psychiatry, 21(3), 339–347.

By: R. Jansen*, B. Penninx*, V. Madar*, K. Xia*, Y. Milaneschi*, J. Hottenga*, A. Hammerschlag*, A. Beekman* ...

Source: Crossref
Added: August 28, 2020

2015 journal article

Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis

Nature Communications, 6.

By: H. Corvol, S. Blackman, P. Boelle, P. Gallins, R. Pace, J. Stonebraker, F. Accurso, A. Clement ...

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis

Nature Communications, 6(1).

By: H. Corvol*, S. Blackman*, P. Boëlle*, P. Gallins*, R. Pace*, J. Stonebraker*, F. Accurso*, A. Clement* ...

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Added: February 5, 2020

2015 journal article

Hypothesis testing at the extremes: fast and robust association for high-throughput data

BIOSTATISTICS, 16(3), 611–625.

By: Y. Zhou & F. Wright

author keywords: Density approximation; Exact testing; Permutation
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Identification of Novel Gene Targets and Putative Regulators of Arsenic-Associated DNA Methylation in Human Urothelial Cells and Bladder Cancer

Chemical Research in Toxicology, 28(6), 1144–1155.

By: J. Rager*, S. Tilley*, S. Tulenko*, L. Smeester*, P. Ray*, A. Yosim*, J. Currier*, M. Ishida* ...

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Added: February 5, 2020

2015 journal article

Identification of novel gene targets and putative regulators of arsenic-associated DNA methylation in human urothelial cells and bladder cancer

Chemical Research in Toxicology, 28(6), 1144–1155.

By: J. Rager, S. Tilley, S. Tulenko, L. Smeester, P. Ray, A. Yosim, J. Currier, M. Ishida ...

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

In vitro screening for population variability in toxicity of pesticide-containing mixtures

ENVIRONMENT INTERNATIONAL, 85, 147–155.

By: N. Abdo*, B. Wetmore*, G. Chappell*, D. Shea, F. Wright & I. Rusyn*

author keywords: Pesticide; Mixture; Population
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Population-Based in Vitro Hazard and Concentration-Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study

ENVIRONMENTAL HEALTH PERSPECTIVES, 123(5), 458–466.

By: N. Abdo*, M. Xia*, C. Brown, O. Kosyk*, R. Huang*, S. Sakamuru*, Y. Zhou, J. Jack ...

Source: Web Of Science
Added: August 6, 2018

2015 journal article

Prediction of human population responses to toxic compounds by a collaborative competition

Nature Biotechnology, 33(9), 933–172.

By: F. Eduati, L. Mangravite, T. Wang, H. Tang, J. Bare, R. Huang, T. Norman, M. Kellen ...

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Prediction of human population responses to toxic compounds by a collaborative competition

Nature Biotechnology, 33(9), 933–940.

By: F. Eduati*, L. Mangravite*, T. Wang*, H. Tang, J. Bare*, R. Huang*, T. Norman*, M. Kellen* ...

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Added: February 24, 2020

2015 journal article

Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

Scientific Reports, 5(1), 15145.

By: J. Yang*, T. Huang*, F. Petralia*, Q. Long*, B. Zhang*, C. Argmann*, Y. Zhao*, C. Mobbs* ...

Source: Crossref
Added: January 4, 2021

2015 journal article

The human transcriptome across tissues and individuals

Science, 348(6235), 660–665.

By: M. Mele, P. Ferreira, F. Reverter, D. DeLuca, J. Monlong, M. Sammeth, T. Young, J. Goldmann ...

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Convergence of sample eigenvalues, eigenvectors, and principal component scores for ultra-high dimensional data

BIOMETRIKA, 101(2), 484–490.

By: S. Lee*, F. Zou* & F. Wright

author keywords: High-dimension low sample size data; Principal component analysis; Random matrix
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Heritability and genomics of gene expression in peripheral blood

Nature Genetics, 46(5), 430–437.

By: F. Wright, P. Sullivan, A. Brooks, F. Zou, W. Sun, K. Xia, V. Madar, R. Jansen ...

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Heritability and genomics of gene expression in peripheral blood

Nature Genetics, 46(5), 430–437.

By: F. Wright, P. Sullivan*, A. Brooks*, F. Zou*, W. Sun*, K. Xia*, V. Madar*, R. Jansen* ...

Source: Crossref
Added: February 5, 2020

2014 journal article

Physiologically Based Pharmacokinetic (PBPK) Modeling of Interstrain Variability in Trichloroethylene Metabolism in the Mouse

ENVIRONMENTAL HEALTH PERSPECTIVES, 122(5), 456–463.

By: W. Chiu*, J. Campbell*, H. Clewell*, Y. Zhou, F. Wright, K. Guyton*, I. Rusyn*

Source: Web Of Science
Added: August 6, 2018

2014 journal article

Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol

The American Journal of Human Genetics, 94(2), 233–245.

By: L. Lange*, Y. Hu*, H. Zhang*, C. Xue*, E. Schmidt*, Z. Tang*, C. Bizon*, E. Lange* ...

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2013 journal article

Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicity

Toxicology and Applied Pharmacology, 273(3), 500–507.

By: O. Sirenko, E. Cromwell, C. Crittenden, J. Wignall, F. Wright & I. Rusyn

author keywords: iPSC; Calcium flux; Cardiotoxicity; hERG; Phenotypic screening; Predictive toxicology
Source: Crossref
Added: August 28, 2020

2013 journal article

Space-time clustering and the permutation moments of quadratic forms

Stat, 2(1), 292–302.

By: Y. Zhou, G. Mayhew*, Z. Sun*, X. Xu*, F. Zou* & F. Wright

author keywords: exact testing; resampling; statistical computing
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Added: February 5, 2020

2013 journal article

The Genotype-Tissue Expression (GTEx) project

Nature Genetics, 45(6), 580–585.

By: J. Lonsdale, J. Thomas*, M. Salvatore*, R. Phillips*, E. Lo*, S. Shad*, R. Hasz*, G. Walters* ...

Source: Crossref
Added: August 28, 2020

2013 journal article

The Value of Statistical or Bioinformatics Annotation for Rare Variant Association With Quantitative Trait

Genetic Epidemiology, 37(7), 666–674.

By: A. Byrnes*, M. Wu*, F. Wright, M. Li* & Y. Li*

author keywords: rare variants; association; weighting; variable selection; variant annotation
Source: Crossref
Added: August 28, 2020

2013 journal article

Unified Analysis of Secondary Traits in Case–Control Association Studies

Journal of the American Statistical Association, 108(502), 566–576.

By: A. Ghosh*, F. Wright & F. Zou*

author keywords: GWAS; Profile likelihood; Pseudo-likelihood; Retrospective study; Secondary phenotype; Semiparametric method
Source: Crossref
Added: August 28, 2020

2012 journal article

Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis

Nature Genetics, 44(8), 886–889.

By: M. Emond*, T. Louie*, J. Emerson*, W. Zhao*, R. Mathias*, M. Knowles*, F. Wright, M. Rieder* ...

Source: Crossref
Added: August 28, 2020

2012 journal article

Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis

Nature Genetics, 44(5), 562–569.

By: L. Sun*, J. Rommens*, H. Corvol*, W. Li*, X. Li*, T. Chiang*, F. Lin*, R. Dorfman* ...

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Added: August 28, 2020

2011 journal article

A novel lung disease phenotype adjusted for mortality attrition for cystic fibrosis Genetic modifier studies

Pediatric Pulmonology, 46(9), 857–869.

By: C. Taylor*, C. Commander*, J. Collaco*, L. Strug*, W. Li*, F. Wright, A. Webel*, R. Pace* ...

author keywords: forced expiratory volume; age effects; severity of illness index
Source: Crossref
Added: August 28, 2020

2011 journal article

Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2

Nature Genetics, 43(6), 539–546.

By: F. Wright, L. Strug*, V. Doshi*, C. Commander*, S. Blackman*, L. Sun*, Y. Berthiaume*, D. Cutler* ...

Source: Crossref
Added: August 28, 2020

2011 journal article

MicroRNA expression in the livers of inbred mice

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 714(1-2), 126–133.

By: D. Gatti*, L. Lu*, R. Williams*, W. Sun*, F. Wright, D. Threadgill, I. Rusyn*

author keywords: MicroRNA; Liver; Mouse; Gene expression
Sources: Crossref, Web Of Science
Added: August 6, 2018

2011 journal article

Nuclear Factor κ-Light Chain-Enhancer of Activated B Cells is Activated by Radiotherapy and is Prognostic for Overall Survival in Patients With Rectal Cancer Treated With Preoperative Fluorouracil-Based Chemoradiotheraphy

International Journal of Radiation Oncology*Biology*Physics, 80(3), 705–711.

By: B. O'Neil*, W. Funkhouser*, B. Calvo*, M. Meyers*, H. Kim*, R. Goldberg*, S. Bernard*, L. Caskey* ...

author keywords: Chemoradiotherapy; NF-kappa B; rectal cancer; prognostic markers; inducible resistance genes; TRAF1; Bcl-2; cIAP-2; interleukin 8
Source: Crossref
Added: January 4, 2021

2010 journal article

An approximate Bayesian approach for quantitative trait loci estimation

Computational Statistics & Data Analysis, 54(2), 565–574.

By: Y. Chang*, F. Zou* & F. Wright

Source: Crossref
Added: August 28, 2020

2010 journal article

Interactome analysis of longitudinal pharyngeal infection of cynomolgus macaques by group A Streptococcus

Proceedings of the National Academy of Sciences, 107(10), 4693–4698.

By: P. Shea*, K. Virtaneva*, J. Kupko*, S. Porcella*, W. Barry*, F. Wright, S. Kobayashi*, A. Carmody* ...

author keywords: epithelial growth factor receptor; host pathogen; microarray; Streptococcus pyogenes; transcriptome
Source: Crossref
Added: August 28, 2020

2010 journal article

Use of Pharmaco-Metabonomics for Early Prediction of Acetaminophen-Induced Hepatotoxicity in Humans

Clinical Pharmacology & Therapeutics, 88(1), 45–51.

By: J. Winnike*, Z. Li*, F. Wright, J. Macdonald*, T. O'Connell* & P. Watkins*

Source: Crossref
Added: August 28, 2020

2009 journal article

A robust QTL mapping procedure

Journal of Statistical Planning and Inference, 139(3), 978–989.

By: F. Zou*, L. Nie*, F. Wright & P. Sen*

author keywords: GEE; Generalized least squares estimate; Quantitative trait; Weighted least squares estimate; Wilcoxon-Mann-Whitney statistic
Source: Crossref
Added: August 28, 2020

2009 journal article

A susceptibility gene for type 2 diabetes confers substantial risk for diabetes complicating cystic fibrosis

Diabetologia, 52(9), 1858–1865.

By: S. Blackman*, S. Hsu*, S. Ritter*, K. Naughton*, F. Wright, M. Drumm*, M. Knowles*, G. Cutting*

author keywords: Association; CFRD; Corticosteroid; Cystic fibrosis; Diabetes; Genetics; Glucocorticoid; Modifier gene; TCF7L2
Source: Crossref
Added: August 28, 2020

2009 journal article

Erratum: Genomewide association for schizophrenia in the CATIE study: results of stage 1

Molecular Psychiatry, 14(12), 1144–1144.

By: P. Sullivan*, D. Lin, J. Tzeng, E. van den Oord, D. Perkins, T. Stroup, M. Wagner, S. Lee ...

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Added: February 24, 2020

2009 journal article

Genetic Modifiers of Liver Disease in Cystic Fibrosis

JAMA, 302(10), 1076–1083.

By: J. Bartlett*, K. Friedman*, S. Ling*, R. Pace*, S. Bell*, B. Bourke*, G. Castaldo*, C. Castellani* ...

Source: Crossref
Added: January 17, 2021

2009 journal article

Replication and narrowing of gene expression quantitative trait loci using inbred mice

Mammalian Genome, 20(7), 437–446.

By: D. Gatti*, A. Harrill*, F. Wright, D. Threadgill* & I. Rusyn*

Source: Crossref
Added: August 28, 2020

2008 journal article

Comment on a Simple and Improved Correction for Population Stratification

The American Journal of Human Genetics, 82(2), 524–526.

By: S. Lee*, P. Sullivan*, F. Zou* & F. Wright

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Added: August 28, 2020

2008 journal article

Estimating Odds Ratios in Genome Scans: An Approximate Conditional Likelihood Approach

The American Journal of Human Genetics, 82(5), 1064–1074.

By: A. Ghosh*, F. Zou* & F. Wright

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Added: August 28, 2020

2008 journal article

Estimating Odds Ratios in Genome Scans: An Approximate Conditional Likelihood Approach

The American Journal of Human Genetics, 82(5), 1224.

By: A. Ghosh, F. Zou & F. Wright

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Added: August 28, 2020

2008 journal article

Genomewide association for schizophrenia in the CATIE study: results of stage 1

Molecular Psychiatry, 13(6), 570–584.

By: P. Sullivan*, D. Lin*, J. Tzeng, E. van den Oord*, D. Perkins*, T. Stroup*, M. Wagner*, S. Lee* ...

author keywords: schizophrenia; genomewide association; CATIE
Sources: Crossref, Web Of Science
Added: August 6, 2018

2005 journal article

Genetic Modifiers of Lung Disease in Cystic Fibrosis

New England Journal of Medicine, 353(14), 1443–1453.

By: M. Drumm*, M. Konstan*, M. Schluchter*, A. Handler*, R. Pace*, F. Zou*, M. Zariwala*, D. Fargo* ...

Source: Crossref
Added: August 28, 2020

2005 journal article

Group A Streptococcus Transcriptome Dynamics during Growth in Human Blood Reveals Bacterial Adaptive and Survival Strategies

The American Journal of Pathology, 166(2), 455–465.

By: M. Graham*, K. Virtaneva*, S. Porcella*, W. Barry*, B. Gowen*, C. Johnson*, F. Wright, J. Musser*

Source: Crossref
Added: August 28, 2020