@article{ford_jang_chen_zhou_gallins_wright_chiu_rusyn_2022, title={A Population-Based Human In Vitro Approach to Quantify Inter-Individual Variability in Responses to Chemical Mixtures}, volume={10}, ISSN={["2305-6304"]}, url={https://doi.org/10.3390/toxics10080441}, DOI={10.3390/toxics10080441}, number={8}, journal={TOXICS}, author={Ford, Lucie C. and Jang, Suji and Chen, Zunwei and Zhou, Yi-Hui and Gallins, Paul J. and Wright, Fred A. and Chiu, Weihsueh A. and Rusyn, Ivan}, year={2022}, month={Aug} } @article{zhou_gallins_etheridge_jima_scholl_wright_innocenti_2022, title={A resource for integrated genomic analysis of the human liver}, volume={12}, ISSN={["2045-2322"]}, url={https://doi.org/10.1038/s41598-022-18506-z}, DOI={10.1038/s41598-022-18506-z}, number={1}, journal={SCIENTIFIC REPORTS}, author={Zhou, Yi-Hui and Gallins, Paul J. and Etheridge, Amy S. and Jima, Dereje and Scholl, Elizabeth and Wright, Fred A. and Innocenti, Federico}, year={2022}, month={Sep} } @article{roman-hubers_cordova_rohde_chiu_mcdonald_wright_dodds_baker_rusyn_2022, title={Characterization of compositional variability in petroleum substances}, volume={317}, ISSN={["1873-7153"]}, DOI={10.1016/j.fuel.2022.123547}, journal={FUEL}, author={Roman-Hubers, Alina T. and Cordova, Alexandra C. and Rohde, Arlean M. and Chiu, Weihsueh A. and McDonald, Thomas J. and Wright, Fred A. and Dodds, James N. and Baker, Erin S. and Rusyn, Ivan}, year={2022}, month={Jun} } @article{boysen_rusyn_chiu_wright_2022, title={Characterization of population variability of 1,3-butadiene derived protein adducts in humans and mice}, volume={132}, ISSN={["1096-0295"]}, DOI={10.1016/j.yrtph.2022.105171}, journal={REGULATORY TOXICOLOGY AND PHARMACOLOGY}, author={Boysen, Gunnar and Rusyn, Ivan and Chiu, Weihsueh A. and Wright, Fred A.}, year={2022}, month={Jul} } @article{mandal_levy_ives_hwang_zhou_motsinger-reif_pan_huggins_hamilton_wright_et al._2022, title={Correlation Analysis of Variables From the Atherosclerosis Risk in Communities Study}, volume={13}, ISSN={["1663-9812"]}, DOI={10.3389/fphar.2022.883433}, journal={FRONTIERS IN PHARMACOLOGY}, author={Mandal, Meisha and Levy, Josh and Ives, Cataia and Hwang, Stephen and Zhou, Yi-Hui and Motsinger-Reif, Alison and Pan, Huaqin and Huggins, Wayne and Hamilton, Carol and Wright, Fred and et al.}, year={2022}, month={Jul} } @article{ting_wright_zhou_2022, title={Fast Multivariate Probit Estimation via a Two-Stage Composite Likelihood}, volume={2}, ISSN={["1867-1772"]}, url={https://doi.org/10.1007/s12561-022-09338-6}, DOI={10.1007/s12561-022-09338-6}, journal={STATISTICS IN BIOSCIENCES}, author={Ting, Bryan and Wright, Fred and Zhou, Yi-Hui}, year={2022}, month={Feb} } @article{jima_skaar_planchart_motsinger-reif_cevik_park_cowley_wright_house_liu_et al._2022, title={Genomic map of candidate human imprint control regions: the imprintome}, volume={6}, ISSN={["1559-2308"]}, url={https://doi.org/10.1080/15592294.2022.2091815}, DOI={10.1080/15592294.2022.2091815}, journal={EPIGENETICS}, author={Jima, Dereje D. and Skaar, David A. and Planchart, Antonio and Motsinger-Reif, Alison and Cevik, Sebnem E. and Park, Sarah S. and Cowley, Michael and Wright, Fred and House, John and Liu, Andy and et al.}, year={2022}, month={Jun} } @article{house_grimm_klaren_dalzell_kuchi_zhang_lenz_boogaard_ketelslegers_gant_et al._2022, title={Grouping of UVCB Substances with Dose-Response Transcriptomics Data from Human Cell-Based Assays}, volume={39}, ISSN={["1868-8551"]}, DOI={10.14573/altex.2107051}, number={3}, journal={ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION}, author={House, John S. and Grimm, Fabian A. and Klaren, William D. and Dalzell, Abigail and Kuchi, Srikeerthana and Zhang, Shu-Dong and Lenz, Klaus and Boogaard, Peter J. and Ketelslegers, Hans B. and Gant, Timothy W. and et al.}, year={2022}, pages={388–404} } @article{harlow_gandawijaya_bamford_martin_wood_most_tanaka_leonard_etheridge_innocenti_et al._2022, title={Identification and single-base gene-editing functional validation of a cis-EPO variant as a genetic predictor for EPO-increasing therapies}, volume={109}, ISSN={["1537-6605"]}, DOI={10.1016/j.ajhg.2022.08.004}, number={9}, journal={AMERICAN JOURNAL OF HUMAN GENETICS}, author={Harlow, Charli E. and Gandawijaya, Josan and Bamford, Rosemary A. and Martin, Emily-Rose and Wood, Andrew R. and Most, Peter J. and Tanaka, Toshiko and Leonard, Hampton L. and Etheridge, Amy S. and Innocenti, Federico and et al.}, year={2022}, month={Sep}, pages={1638–1652} } @article{sun_liu_rosen_huang_pace_dang_gallins_blue_ling_corvol_et al._2022, title={Leveraging TOPMed imputation server and constructing a cohort-specific imputation reference panel to enhance genotype imputation among cystic fibrosis patients}, volume={3}, ISSN={["2666-2477"]}, DOI={10.1016/j.xhgg.2022.100090}, number={2}, journal={HUMAN GENETICS AND GENOMICS ADVANCES}, author={Sun, Quan and Liu, Weifang and Rosen, Jonathan D. and Huang, Le and Pace, Rhonda G. and Dang, Hong and Gallins, Paul J. and Blue, Elizabeth E. and Ling, Hua and Corvol, Harriet and et al.}, year={2022}, month={Apr} } @article{sun_yang_rosen_jiang_chen_liu_wen_raffield_pace_zhou_et al._2022, title={MagicalRsq: Machine-learning-based genotype imputation quality calibration}, volume={109}, ISSN={["1537-6605"]}, DOI={10.1016/j.ajhg.2022.09.009}, number={11}, journal={AMERICAN JOURNAL OF HUMAN GENETICS}, author={Sun, Quan and Yang, Yingxi and Rosen, Jonathan D. and Jiang, Min-Zhi and Chen, Jiawen and Liu, Weifang and Wen, Jia and Raffield, Laura M. and Pace, Rhonda G. and Zhou, Yi-Hui and et al.}, year={2022}, month={Nov}, pages={1986–1997} } @article{rusyn_chiu_wright_2022, title={Model systems and organisms for addressing inter- and intra-species variability in risk assessment}, volume={132}, ISSN={["1096-0295"]}, DOI={10.1016/j.yrtph.2022.105197}, journal={REGULATORY TOXICOLOGY AND PHARMACOLOGY}, author={Rusyn, Ivan and Chiu, Weihsueh A. and Wright, Fred A.}, year={2022}, month={Jul} } @article{aksit_ling_pace_raraigh_onchiri_faino_pagel_pugh_stilp_sun_et al._2022, title={Pleiotropic modifiers of age-related diabetes and neonatal intestinal obstruction in cystic fibrosis}, volume={109}, ISSN={["1537-6605"]}, DOI={10.1016/j.ajhg.2022.09.004}, number={10}, journal={AMERICAN JOURNAL OF HUMAN GENETICS}, author={Aksit, Melis A. and Ling, Hua and Pace, Rhonda G. and Raraigh, Karen S. and Onchiri, Frankline and Faino, Anna V. and Pagel, Kymberleigh and Pugh, Elizabeth and Stilp, Adrienne M. and Sun, Quan and et al.}, year={2022}, month={Oct}, pages={1894–1908} } @article{bhandari_casillas_aly_zhu_newman_wright_miller_adler_rusyn_chiu_2022, title={Spatial and Temporal Analysis of Impacts of Hurricane Florence on Criteria Air Pollutants and Air Toxics in Eastern North Carolina}, volume={19}, ISSN={["1660-4601"]}, DOI={10.3390/ijerph19031757}, number={3}, journal={INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH}, author={Bhandari, Sharmila and Casillas, Gaston and Aly, Noor A. and Zhu, Rui and Newman, Galen and Wright, Fred A. and Miller, Anthony and Adler, Gabriela and Rusyn, Ivan and Chiu, Weihsueh A.}, year={2022}, month={Feb} } @article{xia_shabalin_yin_chung_sullivan_wright_styner_gilmore_santelli_zou_2022, title={TwinEQTL: ultrafast and powerful association analysis for eQTL and GWAS in twin studies}, ISSN={["1943-2631"]}, DOI={10.1093/genetics/iyac088}, journal={GENETICS}, author={Xia, Kai and Shabalin, Andrey A. and Yin, Zhaoyu and Chung, Wonil and Sullivan, Patrick F. and Wright, Fred A. and Styner, Martin and Gilmore, John H. and Santelli, Rebecca C. and Zou, Fei}, year={2022}, month={Jun} } @article{wang_rivenbark_gong_wright_phillips_2021, title={Application of Edible Montmorillonite Clays for the Adsorption and Detoxification of Microcystin}, volume={4}, ISSN={["2576-6422"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-85115268354&partnerID=MN8TOARS}, DOI={10.1021/acsabm.1c00779}, number={9}, journal={ACS APPLIED BIO MATERIALS}, author={Wang, Meichen and Rivenbark, Kelly and Gong, Joonho and Wright, Fred A. and Phillips, Timothy D.}, year={2021}, month={Sep}, pages={7254–7265} } @article{roman-hubers_cordova_aly_mcdonald_lloyd_wright_baker_chiu_rusyn_2021, title={Data Processing Workflow to Identify Structurally Related Compounds in Petroleum Substances Using Ion Mobility Spectrometry-Mass Spectrometry}, volume={35}, ISSN={["1520-5029"]}, DOI={10.1021/acs.energyfuels.1c00892}, number={13}, journal={ENERGY & FUELS}, author={Roman-Hubers, Alina T. and Cordova, Alexandra C. and Aly, Noor A. and McDonald, Thomas J. and Lloyd, Dillon T. and Wright, Fred A. and Baker, Erin S. and Chiu, Weihsueh A. and Rusyn, Ivan}, year={2021}, month={Jul}, pages={10529–10539} } @article{aly_casillas_luo_mcdonald_wade_zhu_newman_lloyd_wright_chiu_et al._2021, title={Environmental impacts of Hurricane Florence flooding in eastern North Carolina: temporal analysis of contaminant distribution and potential human health risks}, volume={31}, ISSN={["1559-064X"]}, DOI={10.1038/s41370-021-00325-5}, number={5}, journal={JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY}, author={Aly, Noor A. and Casillas, Gaston and Luo, Yu-Syuan and McDonald, Thomas J. and Wade, Terry L. and Zhu, Rui and Newman, Galen and Lloyd, Dillon and Wright, Fred A. and Chiu, Weihsueh A. and et al.}, year={2021}, month={Sep}, pages={810–822} } @article{house_grimm_klaren_dalzell_kuchi_zhang_lenz_boogaard_ketelslegers_gant_et al._2021, title={Grouping of UVCB Substances with New Approach Methodologies (NAMs) Data}, volume={38}, ISSN={["1868-8551"]}, DOI={10.14573/altex.2006262}, number={1}, journal={ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION}, author={House, John S. and Grimm, Fabian A. and Klaren, William D. and Dalzell, Abigail and Kuchi, Srikeerthana and Zhang, Shu-Dong and Lenz, Klaus and Boogaard, Peter J. and Ketelslegers, Hans B. and Gant, Timothy W. and et al.}, year={2021}, pages={123–137} } @article{erber_goodman_wright_chiu_tretyakova_rusyn_2021, title={Intra- and Inter-Species Variability in Urinary N7-(1-Hydroxy-3-buten-2-yl)guanine Adducts Following Inhalation Exposure to 1,3-Butadiene}, volume={34}, ISSN={["1520-5010"]}, DOI={10.1021/acs.chemrestox.1c00291}, number={11}, journal={CHEMICAL RESEARCH IN TOXICOLOGY}, author={Erber, Luke and Goodman, Samantha and Wright, Fred A. and Chiu, Weihsueh A. and Tretyakova, Natalia Y. and Rusyn, Ivan}, year={2021}, month={Nov}, pages={2375–2383} } @article{chen_jang_kaihatu_zhou_wright_chiu_rusyn_2021, title={Potential Human Health Hazard of Post-Hurricane Harvey Sediments in Galveston Bay and Houston Ship Channel: A Case Study of Using In Vitro Bioactivity Data to Inform Risk Management Decisions}, volume={18}, ISSN={["1660-4601"]}, url={https://doi.org/10.3390/ijerph182413378}, DOI={10.3390/ijerph182413378}, number={24}, journal={INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH}, author={Chen, Zunwei and Jang, Suji and Kaihatu, James M. and Zhou, Yi-Hui and Wright, Fred A. and Chiu, Weihsueh A. and Rusyn, Ivan}, year={2021}, month={Dec} } @article{luo_chen_blanchette_zhou_wright_baker_chiu_rusyn_2021, title={Relationships between constituents of energy drinks and beating parameters in human induced pluripotent stem cell (iPSC)-Derived cardiomyocytes}, volume={149}, ISSN={["1873-6351"]}, url={https://doi.org/10.1016/j.fct.2021.111979}, DOI={10.1016/j.fct.2021.111979}, journal={FOOD AND CHEMICAL TOXICOLOGY}, author={Luo, Yu-Syuan and Chen, Zunwei and Blanchette, Alexander D. and Zhou, Yi-Hui and Wright, Fred A. and Baker, Erin S. and Chiu, Weihsueh A. and Rusyn, Ivan}, year={2021}, month={Mar} } @article{chen_lloyd_zhou_chiu_wright_rusyn_2021, title={Risk Characterization of Environmental Samples Using In Vitro Bioactivity and Polycyclic Aromatic Hydrocarbon Concentrations Data}, volume={179}, ISSN={["1096-0929"]}, DOI={10.1093/toxsci/kfaa166}, number={1}, journal={TOXICOLOGICAL SCIENCES}, author={Chen, Zunwei and Lloyd, Dillon and Zhou, Yi-Hui and Chiu, Weihsueh A. and Wright, Fred A. and Rusyn, Ivan}, year={2021}, month={Jan}, pages={108–120} } @misc{marvel_house_wheeler_song_zhou_wright_chiu_rusyn_motsinger-reif_reif_2021, title={The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning}, volume={129}, ISSN={["1552-9924"]}, DOI={10.1289/EHP8690}, number={1}, journal={ENVIRONMENTAL HEALTH PERSPECTIVES}, author={Marvel, Skylar W. and House, John S. and Wheeler, Matthew and Song, Kuncheng and Zhou, Yi-Hui and Wright, Fred A. and Chiu, Weihsueh A. and Rusyn, Ivan and Motsinger-Reif, Alison and Reif, David M.}, year={2021}, month={Jan} } @article{etheridge_gallins_jima_broadaway_ratain_schuetz_schadt_schroder_molony_zhou_et al._2020, title={A New Liver Expression Quantitative Trait Locus Map From 1,183 Individuals Provides Evidence for Novel Expression Quantitative Trait Loci of Drug Response, Metabolic, and Sex-Biased Phenotypes}, volume={107}, ISSN={["1532-6535"]}, DOI={10.1002/cpt.1751}, number={6}, journal={CLINICAL PHARMACOLOGY & THERAPEUTICS}, author={Etheridge, Amy S. and Gallins, Paul J. and Jima, Dereje and Broadaway, K. Alaine and Ratain, Mark J. and Schuetz, Erin and Schadt, Eric and Schroder, Adrian and Molony, Cliona and Zhou, Yihui and et al.}, year={2020}, month={Jun}, pages={1383–1393} } @article{mukherjee_beykal_szafran_onel_stossi_mancini_lloyd_wright_zhou_mancini_et al._2020, title={Classification of estrogenic compounds by coupling high content analysis and machine learning algorithms}, volume={16}, ISSN={["1553-7358"]}, DOI={10.1371/journal.pcbi.1008191}, number={9}, journal={PLOS COMPUTATIONAL BIOLOGY}, author={Mukherjee, Rajib and Beykal, Burcu and Szafran, Adam T. and Onel, Melis and Stossi, Fabio and Mancini, Maureen G. and Lloyd, Dillon and Wright, Fred A. and Zhou, Lan and Mancini, Michael A. and et al.}, year={2020}, month={Sep} } @article{house_bouzos_fahy_francisco_lloyd_wright_motsinger-reif_asuri_wheeler_2020, title={Low-Dose Silver Nanoparticle Surface Chemistry and Temporal Effects on Gene Expression in Human Liver Cells}, volume={16}, ISSN={["1613-6829"]}, DOI={10.1002/smll.202000299}, number={21}, journal={SMALL}, author={House, John S. and Bouzos, Evangelia and Fahy, Kira M. and Francisco, Victorino Miguel and Lloyd, Dillon T. and Wright, Fred A. and Motsinger-Reif, Alison A. and Asuri, Prashanth and Wheeler, Korin E.}, year={2020}, month={May} } @misc{rusyn_chiu_wright_2020, title={Questioning Existing Cancer Hazard Evaluation Standards in the Name of Statistics}, volume={177}, ISSN={["1096-0929"]}, DOI={10.1093/toxsci/kfaa077}, number={2}, journal={TOXICOLOGICAL SCIENCES}, author={Rusyn, Ivan and Chiu, Weihsueh A. and Wright, Fred A.}, year={2020}, month={Oct}, pages={521–522} } @article{chen_liu_wright_chiu_rusyn_2020, title={Rapid Hazard Characterization of Environmental Chemicals Using a Compendium of Human Cell Lines from Different Organs}, volume={37}, ISSN={["1868-8551"]}, DOI={10.14573/altex.2002291}, number={4}, journal={ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION}, author={Chen, Zunwei and Liu, Yizhong and Wright, Fred A. and Chiu, Weihsueh A. and Rusyn, Ivan}, year={2020}, pages={623–638} } @article{song_wright_zhou_2020, title={Systematic Comparisons for Composition Profiles, Taxonomic Levels, and Machine Learning Methods for Microbiome-Based Disease Prediction}, volume={7}, ISSN={["2296-889X"]}, DOI={10.3389/fmolb.2020.610845}, journal={FRONTIERS IN MOLECULAR BIOSCIENCES}, author={Song, Kuncheng and Wright, Fred A. and Zhou, Yi-Hui}, year={2020}, month={Dec} } @article{aguet_barbeira_bonazzola_brown_castel_jo_kasela_kim-hellmuth_liang_parsana_et al._2020, title={The GTEx Consortium atlas of genetic regulatory effects across human tissues}, volume={369}, ISSN={["1095-9203"]}, DOI={10.1126/science.aaz1776}, number={6509}, journal={SCIENCE}, author={Aguet, Francois and Barbeira, Alvaro N. and Bonazzola, Rodrigo and Brown, Andrew and Castel, Stephane E. and Jo, Brian and Kasela, Silva and Kim-Hellmuth, Sarah and Liang, Yanyu and Parsana, Princy and et al.}, year={2020}, month={Sep}, pages={1318–1330} } @article{miikherjee_onel_beykal_szafran_stossi_mancini_zhou_wright_pistikopoulos_2019, title={Development of the Texas A&M Superfund Research Program Computational Platform for Data Integration, Visualization, and Analysis}, volume={46}, ISBN={["978-0-12-819939-8"]}, ISSN={["1570-7946"]}, DOI={10.1016/B978-0-12-818634-3.50162-4}, journal={29TH EUROPEAN SYMPOSIUM ON COMPUTER AIDED PROCESS ENGINEERING, PT A}, author={Miikherjee, Rajib and Onel, Melis and Beykal, Burcu and Szafran, Adam T. and Stossi, Fabio and Mancini, Michael A. and Zhou, Lan and Wright, Fred A. and Pistikopoulos, Efstratios N.}, year={2019}, pages={967–972} } @article{onel_beykal_ferguson_chiu_mcdonald_zhou_house_wright_sheen_rusyn_et al._2019, title={Grouping of complex substances using analytical chemistry data: A framework for quantitative evaluation and visualization}, volume={14}, ISSN={["1932-6203"]}, DOI={10.1371/journal.pone.0223517}, number={10}, journal={PLOS ONE}, author={Onel, Melis and Beykal, Burcu and Ferguson, Kyle and Chiu, Weihsueh A. and McDonald, Thomas J. and Zhou, Lan and House, John S. and Wright, Fred A. and Sheen, David A. and Rusyn, Ivan and et al.}, year={2019}, month={Oct} } @article{grimm_house_wilson_sirenko_iwata_wright_ball_rusyn_2019, title={Multi-dimensional in vitro bioactivity profiling for grouping of glycol ethers}, volume={101}, ISSN={["1096-0295"]}, DOI={10.1016/j.yrtph.2018.11.011}, journal={REGULATORY TOXICOLOGY AND PHARMACOLOGY}, author={Grimm, Fabian A. and House, John S. and Wilson, Melinda R. and Sirenko, Oksana and Iwata, Yasuhiro and Wright, Fred A. and Ball, Nicholas and Rusyn, Ivan}, year={2019}, month={Feb}, pages={91–102} } @article{lewis_borowa-mazgaj_conti_chappell_luo_bodnar_konganti_wright_threadgill_chiu_et al._2019, title={Population-Based Analysis of DNA Damage and Epigenetic Effects of 1,3-Butadiene in the Mouse}, volume={32}, ISSN={["1520-5010"]}, DOI={10.1021/acs.chemrestox.9b00035}, number={5}, journal={CHEMICAL RESEARCH IN TOXICOLOGY}, author={Lewis, Lauren and Borowa-Mazgaj, Barbara and Conti, Aline and Chappell, Grace A. and Luo, Yu-Syuan and Bodnar, Wanda and Konganti, Kranti and Wright, Fred A. and Threadgill, David W. and Chiu, Weihsueh A. and et al.}, year={2019}, month={May}, pages={887–898} } @article{luo_cichocki_hsieh_lewis_wright_threadgill_chiu_rusyn_2019, title={Using Collaborative Cross Mouse Population to Fill Data Gaps in Risk Assessment: A Case Study of Population-Based Analysis of Toxicokinetics and Kidney Toxicodynamics of Tetrachloroethylene}, volume={127}, ISSN={["1552-9924"]}, DOI={10.1289/EHP5105}, number={6}, journal={ENVIRONMENTAL HEALTH PERSPECTIVES}, author={Luo, Yu-Syuan and Cichocki, Joseph A. and Hsieh, Nan-Hung and Lewis, Lauren and Wright, Fred A. and Threadgill, David W. and Chiu, Weihsueh A. and Rusyn, Ivan}, year={2019}, month={Jun} } @article{grimm_blanchette_house_ferguson_hsieh_dalaijamts_wright_anson_wright_chiu_et al._2018, title={A Human Population-Based Organotypic In Vitro Model for Cardiotoxicity Screening}, volume={35}, ISSN={["1868-8551"]}, DOI={10.14573/altex.1805301}, number={4}, journal={ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION}, author={Grimm, Fabian A. and Blanchette, Alexander and House, John S. and Ferguson, Kyle and Hsieh, Nan-Hung and Dalaijamts, Chimeddulam and Wright, Alec A. and Anson, Blake and Wright, Fred A. and Chiu, Weihsueh A. and et al.}, year={2018}, pages={441–452} } @article{frayling_beaumont_jones_yaghootkar_tuke_ruth_casanova_west_locke_sharp_et al._2018, title={A common allele in FGF21 associated with sugar intake is associated with body shape, lower total body-fat percentage, and higher blood pressure}, volume={23}, number={2}, journal={Cell reports}, author={Frayling, T. M. and Beaumont, R. N. and Jones, S. E. and Yaghootkar, H. and Tuke, M. A. and Ruth, K. S. and Casanova, F. and West, B. and Locke, J. and Sharp, S. and et al.}, year={2018}, pages={327–336} } @article{polineni_dang_gallins_jones_pace_stonebraker_commander_krenicky_zhou_corvol_et al._2018, title={Airway mucosal host defense is key to genomic regulation of cystic fibrosis lung disease severity}, volume={197}, number={1}, journal={American Journal of Respiratory and Critical Care Medicine}, author={Polineni, D. and Dang, H. and Gallins, P. J. and Jones, L. C. and Pace, R. G. and Stonebraker, J. R. and Commander, L. A. and Krenicky, J. E. and Zhou, Y. H. and Corvol, H. and et al.}, year={2018}, pages={79–93} } @article{li_shabalin_rusyn_wright_nobel_2018, title={An empirical Bayes approach for multiple tissue eQTL analysis}, volume={19}, DOI={10.1093/biostatistics/kxx048}, number={3}, journal={Biostatistics (Oxford, England)}, author={Li, G. and Shabalin, A. A. and Rusyn, I. and Wright, F. A. and Nobel, A. B.}, year={2018}, pages={391–406} } @article{zhou_marron_wright_2018, title={Computation of ancestry scores with mixed families and unrelated individuals}, volume={74}, ISSN={["1541-0420"]}, url={https://doi.org/10.1111/biom.12708}, DOI={10.1111/biom.12708}, number={1}, journal={BIOMETRICS}, publisher={Wiley}, author={Zhou, Yi-Hui and Marron, James S. and Wright, Fred A.}, year={2018}, month={Mar}, pages={155–164} } @article{palowitch_shabalin_zhou_nobel_wright_2018, title={Estimation of cis-eQTL effect sizes using a log of linear model}, volume={74}, ISSN={["1541-0420"]}, url={https://doi.org/10.1111/biom.12810}, DOI={10.1111/biom.12810}, number={2}, journal={BIOMETRICS}, publisher={Wiley}, author={Palowitch, John and Shabalin, Andrey and Zhou, Yi-Hui and Nobel, Andrew B. and Wright, Fred A.}, year={2018}, month={Jun}, pages={616–625} } @article{li_jima_wright_nobel_2018, title={HT-eQTL: integrative expression quantitative trait loci analysis in a large number of human tissues}, volume={19}, journal={BMC Bioinformatics}, author={Li, G. and Jima, D. and Wright, F. A. and Nobel, A. B.}, year={2018} } @article{house_mendez_maguire_gonzalez-nahm_huang_daniels_murphy_fuemmeler_wright_hoyo_2018, title={Periconceptional Maternal Mediterranean Diet Is Associated With Favorable Offspring Behaviors and Altered CpG Methylation of Imprinted Genes}, volume={6}, DOI={10.3389/fcell.2018.00107}, journal={FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY}, author={House, John S. and Mendez, Michelle and Maguire, Rachel L. and Gonzalez-Nahm, Sarah and Huang, Zhiqing and Daniels, Julie and Murphy, Susan K. and Fuemmeler, Bernard F. and Wright, Fred A. and Hoyo, Cathrine}, year={2018} } @article{singleton_lee_dickey_stroud_scholl_wright_aitken_2018, title={Polyphasic characterization of four soil-derived phenanthrene-degrading Acidovorax strains and proposal of Acidovorax carolinensis sp nov.}, volume={41}, ISSN={["0723-2020"]}, DOI={10.1016/j.syapm.2018.06.001}, number={5}, journal={SYSTEMATIC AND APPLIED MICROBIOLOGY}, author={Singleton, David R. and Lee, Janice and Dickey, Allison N. and Stroud, Aaron and Scholl, Elizabeth H. and Wright, Fred A. and Aitken, Michael D.}, year={2018}, month={Sep}, pages={460–472} } @article{venkatratnam_house_konganti_mckenney_threadgill_chiu_aylor_wright_rusyn_2018, title={Population-based dose-response analysis of liver transcriptional response to trichloroethylene in mouse}, volume={29}, ISSN={["1432-1777"]}, DOI={10.1007/s00335-018-9734-y}, number={1-2}, journal={MAMMALIAN GENOME}, author={Venkatratnam, Abhishek and House, John S. and Konganti, Kranti and McKenney, Connor and Threadgill, David W. and Chiu, Weihsueh A. and Aylor, David L. and Wright, Fred A. and Rusyn, Ivan}, year={2018}, month={Feb}, pages={168–181} } @article{marvel_to_grimm_wright_rusyn_reif_2018, title={ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models}, volume={19}, journal={BMC Bioinformatics}, author={Marvel, S. W. and To, K. and Grimm, F. A. and Wright, F. A. and Rusyn, I. and Reif, D. M.}, year={2018} } @article{house_grimm_jima_zhou_rusyn_wright_2017, title={A Pipeline for high-throughput concentration response modeling of gene expression for toxicogenomics}, volume={8}, journal={Frontiers in Genetics}, author={House, J. S. and Grimm, F. A. and Jima, D. D. and Zhou, Y. H. and Rusyn, I. and Wright, F. A.}, year={2017} } @article{rudra_zhou_wright_2017, title={A procedure to detect general association based on concentration of ranks}, volume={6}, number={1}, journal={Stat}, author={Rudra, P. and Zhou, Y. H. and Wright, F. A.}, year={2017}, pages={88–101} } @article{chiu_wright_rusyn_2017, title={A tiered, Bayesian approach to estimating population variability for regulatory decision-making}, volume={34}, number={3}, journal={Altex-alternatives to Animal Experimentation}, author={Chiu, W. A. and Wright, F. A. and Rusyn, I.}, year={2017}, pages={377–388} } @article{henriquez_house_miller_snow_fisher_ren_schladweiler_ledbetter_wright_kodavanti_2017, title={Adrenal-derived stress hormones modulate ozone-induced lung injury and inflammation}, volume={329}, ISSN={["1096-0333"]}, DOI={10.1016/j.taap.2017.06.009}, journal={TOXICOLOGY AND APPLIED PHARMACOLOGY}, author={Henriquez, Andres and House, John and Miller, Desinia B. and Snow, Samantha J. and Fisher, Anna and Ren, Hongzu and Schladweiler, Mette C. and Ledbetter, Allen D. and Wright, Fred and Kodavanti, Urmila P.}, year={2017}, month={Aug}, pages={249–258} } @article{lee_sun_wright_zou_2017, title={An improved and explicit surrogate variable analysis procedure by coefficient adjustment}, volume={104}, ISSN={["1464-3510"]}, DOI={10.1093/biomet/asx018}, number={2}, journal={BIOMETRIKA}, author={Lee, Seunggeun and Sun, Wei and Wright, Fred A. and Zou, Fei}, year={2017}, month={Jun}, pages={303–316} } @article{jansen_hottenga_nivard_abdellaoui_laport_geus_wright_penninx_boomsma_2017, title={Conditional eQTL analysis reveals allelic heterogeneity of gene expression}, volume={26}, ISSN={["1460-2083"]}, DOI={10.1093/hmg/ddx043}, number={8}, journal={HUMAN MOLECULAR GENETICS}, author={Jansen, Rick and Hottenga, Jouke-Jan and Nivard, Michel G. and Abdellaoui, Abdel and Laport, Bram and Geus, Eco J. and Wright, Fred A. and Penninx, Brenda W. J. H. and Boomsma, Dorret I.}, year={2017}, month={Apr}, pages={1444–1451} } @article{tan_li_shanmugam_piskol_kohler_young_liu_zhang_ramaswami_ariyoshi_et al._2017, title={Dynamic landscape and regulation of RNA editing in mammals}, volume={550}, ISSN={0028-0836 1476-4687}, url={http://dx.doi.org/10.1038/NATURE24041}, DOI={10.1038/NATURE24041}, number={7675}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Tan, Meng How and Li, Qin and Shanmugam, Raghuvaran and Piskol, Robert and Kohler, Jennefer and Young, Amy N. and Liu, Kaiwen Ivy and Zhang, Rui and Ramaswami, Gokul and Ariyoshi, Kentaro and et al.}, year={2017}, month={Oct}, pages={249–254} } @article{venkatratnam_furuya_kosyk_gold_bodnar_konganti_threadgill_gillespie_aylor_wright_et al._2017, title={Editor's Highlight: Collaborative Cross Mouse Population Enables Refinements to Characterization of the Variability in Toxicokinetics of Trichloroethylene and Provides Genetic Evidence for the Role of PPAR Pathway in Its Oxidative Metabolism}, volume={158}, ISSN={["1096-0929"]}, DOI={10.1093/toxsci/kfx065}, number={1}, journal={TOXICOLOGICAL SCIENCES}, author={Venkatratnam, Abhishek and Furuya, Shinji and Kosyk, Oksana and Gold, Avram and Bodnar, Wanda and Konganti, Kranti and Threadgill, David W. and Gillespie, Kevin M. and Aylor, David L. and Wright, Fred A. and et al.}, year={2017}, month={Jul}, pages={48–62} } @article{liu_finucane_gusev_bhatia_gazal_o'connor_bulik-sullivan_wright_sullivan_neale_et al._2017, title={Functional Architectures of Local and Distal Regulation of Gene Expression in Multiple Human Tissues}, volume={100}, ISSN={["1537-6605"]}, DOI={10.1016/j.ajhg.2017.03.002}, number={4}, journal={AMERICAN JOURNAL OF HUMAN GENETICS}, author={Liu, Xuanyao and Finucane, Hilary K. and Gusev, Alexander and Bhatia, Gaurav and Gazal, Steven and O'Connor, Luke and Bulik-Sullivan, Brendan and Wright, Fred A. and Sullivan, Patrick F. and Neale, Benjamin M. and et al.}, year={2017}, month={Apr}, pages={605–616} } @article{aguet_brown_castel_davis_he_jo_mohammadi_park_parsana_segre_et al._2017, title={Genetic effects on gene expression across human tissues}, volume={550}, number={7675}, journal={Nature}, author={Aguet, F. and Brown, A. A. and Castel, S. E. and Davis, J. R. and He, Y. and Jo, B. and Mohammadi, P. and Park, Y. and Parsana, P. and Segre, A. V. and et al.}, year={2017}, pages={204-} } @article{aguet_brown_castel_davis_he_jo_mohammadi_park_parsana_segrè_et al._2017, title={Genetic effects on gene expression across human tissues}, volume={550}, ISSN={0028-0836 1476-4687}, url={http://dx.doi.org/10.1038/NATURE24277}, DOI={10.1038/NATURE24277}, number={7675}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Aguet, François and Brown, Andrew A. and Castel, Stephane E. and Davis, Joe R. and He, Yuan and Jo, Brian and Mohammadi, Pejman and Park, YoSon and Parsana, Princy and Segrè, Ayellet V. and et al.}, editor={Battle, Alexis and Brown, Christopher D. and Engelhardt, Barbara E. and Montgomery, Stephen B.Editors}, year={2017}, month={Oct}, pages={204–213} } @article{tukiainen_villani_yen_rivas_marshall_satija_aguirre_gauthier_fleharty_kirby_et al._2017, title={Landscape of X chromosome inactivation across human tissues}, volume={550}, ISSN={0028-0836 1476-4687}, url={http://dx.doi.org/10.1038/NATURE24265}, DOI={10.1038/NATURE24265}, number={7675}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Tukiainen, Taru and Villani, Alexandra-Chloé and Yen, Angela and Rivas, Manuel A. and Marshall, Jamie L. and Satija, Rahul and Aguirre, Matt and Gauthier, Laura and Fleharty, Mark and Kirby, Andrew and et al.}, year={2017}, month={Oct}, pages={244–248} } @article{li_kim_tsang_davis_damani_chiang_hess_zappala_strober_scott_et al._2017, title={The impact of rare variation on gene expression across tissues}, volume={550}, ISSN={0028-0836 1476-4687}, url={http://dx.doi.org/10.1038/NATURE24267}, DOI={10.1038/NATURE24267}, number={7675}, journal={Nature}, publisher={Springer Science and Business Media LLC}, author={Li, Xin and Kim, Yungil and Tsang, Emily K. and Davis, Joe R. and Damani, Farhan N. and Chiang, Colby and Hess, Gaelen T. and Zappala, Zachary and Strober, Benjamin J. and Scott, Alexandra J. and et al.}, year={2017}, month={Oct}, pages={239–243} } @article{grimm_iwata_sirenko_chappell_wright_reif_braisted_gerhold_yeakley_shepard_et al._2016, title={A chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives}, volume={18}, ISSN={["1463-9270"]}, url={http://europepmc.org/abstract/med/28035192}, DOI={10.1039/c6gc01147k}, number={16}, journal={GREEN CHEMISTRY}, author={Grimm, Fabian A. and Iwata, Yasuhiro and Sirenko, Oksana and Chappell, Grace A. and Wright, Fred A. and Reif, David M. and Braisted, John and Gerhold, David L. and Yeakley, Joanne M. and Shepard, Peter and et al.}, year={2016}, pages={4407–4419} } @article{yang_huang_petralia_long_zhang_argmann_zhao_mobbs_schadt_zhu_et al._2016, title={Erratum: Corrigendum: Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases}, volume={6}, ISSN={2045-2322}, url={http://dx.doi.org/10.1038/SREP19384}, DOI={10.1038/SREP19384}, number={1}, journal={Scientific Reports}, publisher={Springer Science and Business Media LLC}, author={Yang, Jialiang and Huang, Tao and Petralia, Francesca and Long, Quan and Zhang, Bin and Argmann, Carmen and Zhao, Yong and Mobbs, Charles V. and Schadt, Eric E. and Zhu, Jun and et al.}, year={2016}, month={Jan}, pages={19384} } @article{jansen_penninx_madar_xia_milaneschi_hottenga_hammerschlag_beekman_wee_smit_et al._2016, title={Gene expression in major depressive disorder}, volume={21}, number={3}, journal={Molecular Psychiatry}, author={Jansen, R. and Penninx, B. W. J. H. and Madar, V. and Xia, K. and Milaneschi, Y. and Hottenga, J. J. and Hammerschlag, A. R. and Beekman, A. and Wee, N. and Smit, J. H. and et al.}, year={2016}, pages={339–347} } @article{tian_patel_ridpath_chen_zhou_neo_clement_takata_takeda_sale_et al._2016, title={Homologous recombination and translesion DNA synthesis play critical roles on tolerating DNA damage caused by trace levels of hexavalent chromium}, volume={11}, number={12}, journal={PLoS One}, author={Tian, X. and Patel, K. and Ridpath, J. R. and Chen, Y. J. and Zhou, Y. H. and Neo, D. and Clement, J. and Takata, M. and Takeda, S. and Sale, J. and et al.}, year={2016} } @article{gusev_ko_shi_bhatia_chung_penninx_jansen_geus_boomsma_wright_et al._2016, title={Integrative approaches for large-scale transcriptome-wide association studies}, volume={48}, number={3}, journal={Nature Genetics}, author={Gusev, A. and Ko, A. and Shi, H. and Bhatia, G. and Chung, W. and Penninx, B. W. J. H. and Jansen, R. and Geus, E. J. C. and Boomsma, D. I. and Wright, F. A. and et al.}, year={2016}, pages={245–252} } @article{gusev_ko_shi_bhatia_chung_penninx_jansen_de geus_boomsma_wright_et al._2016, title={Integrative approaches for large-scale transcriptome-wide association studies}, volume={48}, ISSN={1061-4036 1546-1718}, url={http://dx.doi.org/10.1038/NG.3506}, DOI={10.1038/NG.3506}, number={3}, journal={Nature Genetics}, publisher={Springer Science and Business Media LLC}, author={Gusev, Alexander and Ko, Arthur and Shi, Huwenbo and Bhatia, Gaurav and Chung, Wonil and Penninx, Brenda W J H and Jansen, Rick and de Geus, Eco J C and Boomsma, Dorret I and Wright, Fred A and et al.}, year={2016}, month={Feb}, pages={245–252} } @inproceedings{theisen_williams_2016, title={Poster: risk-based attack surface approximation}, booktitle={Symposium and Bootcamp on the Science of Security}, author={Theisen, C. and Williams, L.}, year={2016}, pages={121–123} } @article{zhou_wright_2016, title={The projack: a resampling approach to correct for ranking bias in high-throughput studies}, volume={17}, number={1}, journal={Biostatistics (Oxford, England)}, author={Zhou, Y. H. and Wright, F. A.}, year={2016}, pages={54–64} } @article{walter_wright_nobel_2015, title={Consistent testing for recurrent genomic aberrations}, volume={102}, ISSN={["1464-3510"]}, DOI={10.1093/biomet/asv046}, number={4}, journal={BIOMETRIKA}, author={Walter, V. and Wright, F. A. and Nobel, A. B.}, year={2015}, month={Dec}, pages={783–796} } @article{jansen_penninx_madar_xia_milaneschi_hottenga_hammerschlag_beekman_van der wee_smit_et al._2015, title={Erratum: Gene expression in major depressive disorder}, volume={21}, ISSN={1359-4184 1476-5578}, url={http://dx.doi.org/10.1038/MP.2015.94}, DOI={10.1038/MP.2015.94}, number={3}, journal={Molecular Psychiatry}, publisher={Springer Nature}, author={Jansen, R and Penninx, B W J H and Madar, V and Xia, K and Milaneschi, Y and Hottenga, J J and Hammerschlag, A R and Beekman, A and van der Wee, N and Smit, J H and et al.}, year={2015}, month={Jun}, pages={444–444} } @article{eduati_mangravite_wang_tang_bare_huang_norman_kellen_menden_yang_et al._2015, title={Erratum: Prediction of human population responses to toxic compounds by a collaborative competition}, volume={33}, ISSN={1087-0156 1546-1696}, url={http://dx.doi.org/10.1038/NBT1015-1109A}, DOI={10.1038/NBT1015-1109A}, number={10}, journal={Nature Biotechnology}, publisher={Springer Nature}, author={Eduati, Federica and Mangravite, Lara M and Wang, Tao and Tang, Hao and Bare, J Christopher and Huang, Ruili and Norman, Thea and Kellen, Mike and Menden, Michael P and Yang, Jichen and et al.}, year={2015}, month={Oct}, pages={1109–1109} } @article{o’neal_gallins_pace_dang_wolf_jones_guo_zhou_madar_huang_et al._2015, title={Gene Expression in Transformed Lymphocytes Reveals Variation in Endomembrane and HLA Pathways Modifying Cystic Fibrosis Pulmonary Phenotypes}, volume={96}, ISSN={0002-9297}, url={http://dx.doi.org/10.1016/J.AJHG.2014.12.022}, DOI={10.1016/J.AJHG.2014.12.022}, number={2}, journal={The American Journal of Human Genetics}, publisher={Elsevier BV}, author={O’Neal, Wanda K. and Gallins, Paul and Pace, Rhonda G. and Dang, Hong and Wolf, Whitney E. and Jones, Lisa C. and Guo, XueLiang and Zhou, Yi-Hui and Madar, Vered and Huang, Jinyan and et al.}, year={2015}, month={Feb}, pages={318–328} } @article{jansen_penninx_madar_xia_milaneschi_hottenga_hammerschlag_beekman_van der wee_smit_et al._2015, title={Gene expression in major depressive disorder}, volume={21}, ISSN={1359-4184 1476-5578}, url={http://dx.doi.org/10.1038/MP.2015.57}, DOI={10.1038/MP.2015.57}, number={3}, journal={Molecular Psychiatry}, publisher={Springer Nature}, author={Jansen, R and Penninx, B W J H and Madar, V and Xia, K and Milaneschi, Y and Hottenga, J J and Hammerschlag, A R and Beekman, A and van der Wee, N and Smit, J H and et al.}, year={2015}, month={May}, pages={339–347} } @article{corvol_blackman_boelle_gallins_pace_stonebraker_accurso_clement_collaco_dang_et al._2015, title={Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis}, volume={6}, journal={Nature Communications}, author={Corvol, H. and Blackman, S. M. and Boelle, P. Y. and Gallins, P. J. and Pace, R. G. and Stonebraker, J. R. and Accurso, F. J. and Clement, A. and Collaco, J. M. and Dang, H. and et al.}, year={2015} } @article{corvol_blackman_boëlle_gallins_pace_stonebraker_accurso_clement_collaco_dang_et al._2015, title={Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis}, volume={6}, ISSN={2041-1723}, url={http://dx.doi.org/10.1038/NCOMMS9382}, DOI={10.1038/NCOMMS9382}, number={1}, journal={Nature Communications}, publisher={Springer Science and Business Media LLC}, author={Corvol, Harriet and Blackman, Scott M. and Boëlle, Pierre-Yves and Gallins, Paul J. and Pace, Rhonda G. and Stonebraker, Jaclyn R. and Accurso, Frank J. and Clement, Annick and Collaco, Joseph M. and Dang, Hong and et al.}, year={2015}, month={Sep} } @article{zhou_wright_2015, title={Hypothesis testing at the extremes: fast and robust association for high-throughput data}, volume={16}, ISSN={["1468-4357"]}, DOI={10.1093/biostatistics/kxv007}, number={3}, journal={BIOSTATISTICS}, author={Zhou, Yi-Hui and Wright, Fred A.}, year={2015}, month={Jul}, pages={611–625} } @article{rager_tilley_tulenko_smeester_ray_yosim_currier_ishida_gonzález-horta_sánchez-ramírez_et al._2015, title={Identification of Novel Gene Targets and Putative Regulators of Arsenic-Associated DNA Methylation in Human Urothelial Cells and Bladder Cancer}, volume={28}, ISSN={0893-228X 1520-5010}, url={http://dx.doi.org/10.1021/TX500393Y}, DOI={10.1021/TX500393Y}, number={6}, journal={Chemical Research in Toxicology}, publisher={American Chemical Society (ACS)}, author={Rager, Julia E. and Tilley, Sloane K. and Tulenko, Samantha E. and Smeester, Lisa and Ray, Paul D. and Yosim, Andrew and Currier, Jenna M. and Ishida, María C. and González-Horta, Maria del Carmen and Sánchez-Ramírez, Blanca and et al.}, year={2015}, month={Jun}, pages={1144–1155} } @article{rager_tilley_tulenko_smeester_ray_yosim_currier_ishida_gonzalez-horta_sanchez-ramirez_et al._2015, title={Identification of novel gene targets and putative regulators of arsenic-associated DNA methylation in human urothelial cells and bladder cancer}, volume={28}, number={6}, journal={Chemical Research in Toxicology}, author={Rager, J. E. and Tilley, S. K. and Tulenko, S. E. and Smeester, L. and Ray, P. D. and Yosim, A. and Currier, J. M. and Ishida, M. C. and Gonzalez-Horta, M. D. and Sanchez-Ramirez, B. and et al.}, year={2015}, pages={1144–1155} } @article{abdo_wetmore_chappell_shea_wright_rusyn_2015, title={In vitro screening for population variability in toxicity of pesticide-containing mixtures}, volume={85}, ISSN={["1873-6750"]}, url={http://www.scopus.com/inward/record.url?eid=2-s2.0-84941887442&partnerID=MN8TOARS}, DOI={10.1016/j.envint.2015.09.012}, journal={ENVIRONMENT INTERNATIONAL}, author={Abdo, Nour and Wetmore, Barbara A. and Chappell, Grace A. and Shea, Damian and Wright, Fred A. and Rusyn, Ivan}, year={2015}, month={Dec}, pages={147–155} } @article{abdo_xia_brown_kosyk_huang_sakamuru_zhou_jack_gallins_xia_et al._2015, title={Population-Based in Vitro Hazard and Concentration-Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study}, volume={123}, ISSN={["1552-9924"]}, DOI={10.1289/ehp.1408775}, number={5}, journal={ENVIRONMENTAL HEALTH PERSPECTIVES}, author={Abdo, Nour and Xia, Menghang and Brown, Chad C. and Kosyk, Oksana and Huang, Ruili and Sakamuru, Srilatha and Zhou, Yi-Hui and Jack, John R. and Gallins, Paul and Xia, Kai and et al.}, year={2015}, month={May}, pages={458–466} } @article{eduati_mangravite_wang_tang_bare_huang_norman_kellen_menden_yang_et al._2015, title={Prediction of human population responses to toxic compounds by a collaborative competition}, volume={33}, number={9}, journal={Nature Biotechnology}, author={Eduati, F. and Mangravite, L. M. and Wang, T. and Tang, H. and Bare, J. C. and Huang, R. L. and Norman, T. and Kellen, M. and Menden, M. P. and Yang, J. C. and et al.}, year={2015}, pages={933–172} } @article{eduati_mangravite_wang_tang_bare_huang_norman_kellen_menden_yang_et al._2015, title={Prediction of human population responses to toxic compounds by a collaborative competition}, volume={33}, ISSN={1087-0156 1546-1696}, url={http://dx.doi.org/10.1038/NBT.3299}, DOI={10.1038/NBT.3299}, number={9}, journal={Nature Biotechnology}, publisher={Springer Science and Business Media LLC}, author={Eduati, Federica and Mangravite, Lara M and Wang, Tao and Tang, Hao and Bare, J Christopher and Huang, Ruili and Norman, Thea and Kellen, Mike and Menden, Michael P and Yang, Jichen and et al.}, year={2015}, month={Aug}, pages={933–940} } @article{yang_huang_petralia_long_zhang_argmann_zhao_mobbs_schadt_zhu_et al._2015, title={Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases}, volume={5}, ISSN={2045-2322}, url={http://dx.doi.org/10.1038/SREP15145}, DOI={10.1038/SREP15145}, number={1}, journal={Scientific Reports}, publisher={Springer Science and Business Media LLC}, author={Yang, Jialiang and Huang, Tao and Petralia, Francesca and Long, Quan and Zhang, Bin and Argmann, Carmen and Zhao, Yong and Mobbs, Charles V. and Schadt, Eric E. and Zhu, Jun and et al.}, year={2015}, month={Oct}, pages={15145} } @article{mele_ferreira_reverter_deluca_monlong_sammeth_young_goldmann_pervouchine_sullivan_et al._2015, title={The human transcriptome across tissues and individuals}, volume={348}, number={6235}, journal={Science}, author={Mele, M. and Ferreira, P. G. and Reverter, F. and DeLuca, D. S. and Monlong, J. and Sammeth, M. and Young, T. R. and Goldmann, J. M. and Pervouchine, D. D. and Sullivan, T. J. and et al.}, year={2015}, pages={660–665} } @article{lee_zou_wright_2014, title={Convergence of sample eigenvalues, eigenvectors, and principal component scores for ultra-high dimensional data}, volume={101}, ISSN={["1464-3510"]}, DOI={10.1093/biomet/ast064}, number={2}, journal={BIOMETRIKA}, author={Lee, Seunggeun and Zou, Fei and Wright, Fred A.}, year={2014}, month={Jun}, pages={484–490} } @article{wright_sullivan_brooks_zou_sun_xia_madar_jansen_chung_zhou_et al._2014, title={Heritability and genomics of gene expression in peripheral blood}, volume={46}, number={5}, journal={Nature Genetics}, author={Wright, F. A. and Sullivan, P. F. and Brooks, A. I. and Zou, F. and Sun, W. and Xia, K. and Madar, V. and Jansen, R. and Chung, W. I. and Zhou, Y. H. and et al.}, year={2014}, pages={430–437} } @article{wright_sullivan_brooks_zou_sun_xia_madar_jansen_chung_zhou_et al._2014, title={Heritability and genomics of gene expression in peripheral blood}, volume={46}, ISSN={1061-4036 1546-1718}, url={http://dx.doi.org/10.1038/NG.2951}, DOI={10.1038/NG.2951}, number={5}, journal={Nature Genetics}, publisher={Springer Science and Business Media LLC}, author={Wright, Fred A and Sullivan, Patrick F and Brooks, Andrew I and Zou, Fei and Sun, Wei and Xia, Kai and Madar, Vered and Jansen, Rick and Chung, Wonil and Zhou, Yi-Hui and et al.}, year={2014}, month={Apr}, pages={430–437} } @article{chiu_campbell_clewell_zhou_wright_guyton_rusyn_2014, title={Physiologically Based Pharmacokinetic (PBPK) Modeling of Interstrain Variability in Trichloroethylene Metabolism in the Mouse}, volume={122}, ISSN={["1552-9924"]}, DOI={10.1289/ehp.1307623}, number={5}, journal={ENVIRONMENTAL HEALTH PERSPECTIVES}, author={Chiu, Weihsueh A. and Campbell, Jerry L., Jr. and Clewell, Harvey J., III and Zhou, Yi-Hui and Wright, Fred A. and Guyton, Kathryn Z. and Rusyn, Ivan}, year={2014}, month={May}, pages={456–463} } @article{lange_hu_zhang_xue_schmidt_tang_bizon_lange_smith_turner_et al._2014, title={Whole-Exome Sequencing Identifies Rare and Low-Frequency Coding Variants Associated with LDL Cholesterol}, volume={94}, ISSN={0002-9297}, url={http://dx.doi.org/10.1016/J.AJHG.2014.01.010}, DOI={10.1016/J.AJHG.2014.01.010}, number={2}, journal={The American Journal of Human Genetics}, publisher={Elsevier BV}, author={Lange, Leslie A. and Hu, Youna and Zhang, He and Xue, Chenyi and Schmidt, Ellen M. and Tang, Zheng-Zheng and Bizon, Chris and Lange, Ethan M. and Smith, Joshua D. and Turner, Emily H. and et al.}, year={2014}, month={Feb}, pages={233–245} } @article{sirenko_cromwell_crittenden_wignall_wright_rusyn_2013, title={Assessment of beating parameters in human induced pluripotent stem cells enables quantitative in vitro screening for cardiotoxicity}, volume={273}, ISSN={0041-008X}, url={http://dx.doi.org/10.1016/J.TAAP.2013.09.017}, DOI={10.1016/J.TAAP.2013.09.017}, number={3}, journal={Toxicology and Applied Pharmacology}, publisher={Elsevier BV}, author={Sirenko, Oksana and Cromwell, Evan F. and Crittenden, Carole and Wignall, Jessica A. and Wright, Fred A. and Rusyn, Ivan}, year={2013}, month={Dec}, pages={500–507} } @article{zhou_mayhew_sun_xu_zou_wright_2013, title={Space-time clustering and the permutation moments of quadratic forms}, volume={2}, ISSN={2049-1573}, url={http://dx.doi.org/10.1002/STA4.37}, DOI={10.1002/STA4.37}, number={1}, journal={Stat}, publisher={Wiley}, author={Zhou, Yi-Hui and Mayhew, Gregory and Sun, Zhibin and Xu, Xiaolin and Zou, Fei and Wright, Fred A.}, year={2013}, month={Nov}, pages={292–302} } @article{lonsdale_thomas_salvatore_phillips_lo_shad_hasz_walters_garcia_young_et al._2013, title={The Genotype-Tissue Expression (GTEx) project}, volume={45}, ISSN={1061-4036 1546-1718}, url={http://dx.doi.org/10.1038/NG.2653}, DOI={10.1038/NG.2653}, number={6}, journal={Nature Genetics}, publisher={Springer Science and Business Media LLC}, author={Lonsdale, John and Thomas, Jeffrey and Salvatore, Mike and Phillips, Rebecca and Lo, Edmund and Shad, Saboor and Hasz, Richard and Walters, Gary and Garcia, Fernando and Young, Nancy and et al.}, year={2013}, month={May}, pages={580–585} } @article{byrnes_wu_wright_li_li_2013, title={The Value of Statistical or Bioinformatics Annotation for Rare Variant Association With Quantitative Trait}, volume={37}, ISSN={0741-0395}, url={http://dx.doi.org/10.1002/GEPI.21747}, DOI={10.1002/GEPI.21747}, number={7}, journal={Genetic Epidemiology}, publisher={Wiley}, author={Byrnes, Andrea E. and Wu, Michael C. and Wright, Fred A. and Li, Mingyao and Li, Yun}, year={2013}, month={Jul}, pages={666–674} } @article{ghosh_wright_zou_2013, title={Unified Analysis of Secondary Traits in Case–Control Association Studies}, volume={108}, ISSN={0162-1459 1537-274X}, url={http://dx.doi.org/10.1080/01621459.2013.793121}, DOI={10.1080/01621459.2013.793121}, number={502}, journal={Journal of the American Statistical Association}, publisher={Informa UK Limited}, author={Ghosh, Arpita and Wright, Fred A. and Zou, Fei}, year={2013}, month={Jun}, pages={566–576} } @article{emond_louie_emerson_zhao_mathias_knowles_wright_rieder_tabor_nickerson_et al._2012, title={Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis}, volume={44}, ISSN={1061-4036 1546-1718}, url={http://dx.doi.org/10.1038/ng.2344}, DOI={10.1038/ng.2344}, number={8}, journal={Nature Genetics}, publisher={Springer Science and Business Media LLC}, author={Emond, Mary J and Louie, Tin and Emerson, Julia and Zhao, Wei and Mathias, Rasika A and Knowles, Michael R and Wright, Fred A and Rieder, Mark J and Tabor, Holly K and Nickerson, Deborah A and et al.}, year={2012}, month={Jul}, pages={886–889} } @article{sun_rommens_corvol_li_li_chiang_lin_dorfman_busson_parekh_et al._2012, title={Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis}, volume={44}, ISSN={1061-4036 1546-1718}, url={http://dx.doi.org/10.1038/ng.2221}, DOI={10.1038/ng.2221}, number={5}, journal={Nature Genetics}, publisher={Springer Science and Business Media LLC}, author={Sun, Lei and Rommens, Johanna M and Corvol, Harriet and Li, Weili and Li, Xin and Chiang, Theodore A and Lin, Fan and Dorfman, Ruslan and Busson, Pierre-François and Parekh, Rashmi V and et al.}, year={2012}, month={Apr}, pages={562–569} } @article{taylor_commander_collaco_strug_li_wright_webel_pace_stonebraker_naughton_et al._2011, title={A novel lung disease phenotype adjusted for mortality attrition for cystic fibrosis Genetic modifier studies}, volume={46}, ISSN={8755-6863}, url={http://dx.doi.org/10.1002/ppul.21456}, DOI={10.1002/ppul.21456}, number={9}, journal={Pediatric Pulmonology}, publisher={Wiley}, author={Taylor, Chelsea and Commander, Clayton W. and Collaco, Joseph M. and Strug, Lisa J. and Li, Weili and Wright, Fred A. and Webel, Aaron D. and Pace, Rhonda G. and Stonebraker, Jaclyn R. and Naughton, Kathleen and et al.}, year={2011}, month={Apr}, pages={857–869} } @article{wright_strug_doshi_commander_blackman_sun_berthiaume_cutler_cojocaru_collaco_et al._2011, title={Genome-wide association and linkage identify modifier loci of lung disease severity in cystic fibrosis at 11p13 and 20q13.2}, volume={43}, ISSN={1061-4036 1546-1718}, url={http://dx.doi.org/10.1038/ng.838}, DOI={10.1038/ng.838}, number={6}, journal={Nature Genetics}, publisher={Springer Science and Business Media LLC}, author={Wright, Fred A and Strug, Lisa J and Doshi, Vishal K and Commander, Clayton W and Blackman, Scott M and Sun, Lei and Berthiaume, Yves and Cutler, David and Cojocaru, Andreea and Collaco, J Michael and et al.}, year={2011}, month={May}, pages={539–546} } @article{gatti_lu_williams_sun_wright_threadgill_rusyn_2011, title={MicroRNA expression in the livers of inbred mice}, volume={714}, ISSN={0027-5107}, url={http://dx.doi.org/10.1016/j.mrfmmm.2011.05.007}, DOI={10.1016/j.mrfmmm.2011.05.007}, number={1-2}, journal={Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis}, publisher={Elsevier BV}, author={Gatti, Daniel M. and Lu, Lu and Williams, Robert W. and Sun, Wei and Wright, Fred A. and Threadgill, David W. and Rusyn, Ivan}, year={2011}, month={Sep}, pages={126–133} } @article{o'neil_funkhouser_calvo_meyers_kim_goldberg_bernard_caskey_deal_wright_et al._2011, title={Nuclear Factor κ-Light Chain-Enhancer of Activated B Cells is Activated by Radiotherapy and is Prognostic for Overall Survival in Patients With Rectal Cancer Treated With Preoperative Fluorouracil-Based Chemoradiotheraphy}, volume={80}, ISSN={0360-3016}, url={http://dx.doi.org/10.1016/j.ijrobp.2010.02.063}, DOI={10.1016/j.ijrobp.2010.02.063}, number={3}, journal={International Journal of Radiation Oncology*Biology*Physics}, publisher={Elsevier BV}, author={O'Neil, Bert H. and Funkhouser, William K. and Calvo, Benjamin F. and Meyers, Michael O. and Kim, Hong Jin and Goldberg, Richard M. and Bernard, Stephen A. and Caskey, Laura and Deal, Allison M. and Wright, Fred and et al.}, year={2011}, month={Jul}, pages={705–711} } @article{chang_zou_wright_2010, title={An approximate Bayesian approach for quantitative trait loci estimation}, volume={54}, ISSN={0167-9473}, url={http://dx.doi.org/10.1016/j.csda.2009.09.029}, DOI={10.1016/j.csda.2009.09.029}, number={2}, journal={Computational Statistics & Data Analysis}, publisher={Elsevier BV}, author={Chang, Yu-Ling and Zou, Fei and Wright, Fred A.}, year={2010}, month={Feb}, pages={565–574} } @article{shea_virtaneva_kupko_porcella_barry_wright_kobayashi_carmody_ireland_sturdevant_et al._2010, title={Interactome analysis of longitudinal pharyngeal infection of cynomolgus macaques by group A Streptococcus}, volume={107}, ISSN={0027-8424 1091-6490}, url={http://dx.doi.org/10.1073/pnas.0906384107}, DOI={10.1073/pnas.0906384107}, number={10}, journal={Proceedings of the National Academy of Sciences}, publisher={Proceedings of the National Academy of Sciences}, author={Shea, P. R. and Virtaneva, K. and Kupko, J. J. and Porcella, S. F. and Barry, W. T. and Wright, F. A. and Kobayashi, S. D. and Carmody, A. and Ireland, R. M. and Sturdevant, D. E. and et al.}, year={2010}, month={Feb}, pages={4693–4698} } @article{winnike_li_wright_macdonald_o'connell_watkins_2010, title={Use of Pharmaco-Metabonomics for Early Prediction of Acetaminophen-Induced Hepatotoxicity in Humans}, volume={88}, ISSN={0009-9236 1532-6535}, url={http://dx.doi.org/10.1038/clpt.2009.240}, DOI={10.1038/clpt.2009.240}, number={1}, journal={Clinical Pharmacology & Therapeutics}, publisher={Springer Science and Business Media LLC}, author={Winnike, J H and Li, Z and Wright, F A and Macdonald, J M and O'Connell, T M and Watkins, P B}, year={2010}, month={Feb}, pages={45–51} } @article{zou_nie_wright_sen_2009, title={A robust QTL mapping procedure}, volume={139}, ISSN={0378-3758}, url={http://dx.doi.org/10.1016/j.jspi.2008.06.009}, DOI={10.1016/j.jspi.2008.06.009}, number={3}, journal={Journal of Statistical Planning and Inference}, publisher={Elsevier BV}, author={Zou, Fei and Nie, Lei and Wright, Fred. A. and Sen, Pranab K.}, year={2009}, month={Mar}, pages={978–989} } @article{blackman_hsu_ritter_naughton_wright_drumm_knowles_cutting_2009, title={A susceptibility gene for type 2 diabetes confers substantial risk for diabetes complicating cystic fibrosis}, volume={52}, ISSN={0012-186X 1432-0428}, url={http://dx.doi.org/10.1007/s00125-009-1436-2}, DOI={10.1007/s00125-009-1436-2}, number={9}, journal={Diabetologia}, publisher={Springer Science and Business Media LLC}, author={Blackman, S. M. and Hsu, S. and Ritter, S. E. and Naughton, K. M. and Wright, F. A. and Drumm, M. L. and Knowles, M. R. and Cutting, G. R.}, year={2009}, month={Jul}, pages={1858–1865} } @article{sullivan_lin_tzeng_van den oord_perkins_stroup_wagner_lee_wright_zou_et al._2009, title={Erratum: Genomewide association for schizophrenia in the CATIE study: results of stage 1}, volume={14}, ISSN={1359-4184 1476-5578}, url={http://dx.doi.org/10.1038/mp.2008.74}, DOI={10.1038/mp.2008.74}, number={12}, journal={Molecular Psychiatry}, publisher={Springer Science and Business Media LLC}, author={Sullivan, P F and Lin, D and Tzeng, J-Y and van den Oord, E and Perkins, D and Stroup, T S and Wagner, M and Lee, S and Wright, F A and Zou, F and et al.}, year={2009}, month={Nov}, pages={1144–1144} } @article{bartlett_friedman_ling_pace_bell_bourke_castaldo_castellani_cipolli_colombo_et al._2009, title={Genetic Modifiers of Liver Disease in Cystic Fibrosis}, volume={302}, ISSN={0098-7484}, url={http://dx.doi.org/10.1001/jama.2009.1295}, DOI={10.1001/jama.2009.1295}, number={10}, journal={JAMA}, publisher={American Medical Association (AMA)}, author={Bartlett, Jaclyn R. and Friedman, Kenneth J. and Ling, Simon C. and Pace, Rhonda G. and Bell, Scott C. and Bourke, Billy and Castaldo, Giuseppe and Castellani, Carlo and Cipolli, Marco and Colombo, Carla and et al.}, year={2009}, month={Sep}, pages={1076–1083} } @article{gatti_harrill_wright_threadgill_rusyn_2009, title={Replication and narrowing of gene expression quantitative trait loci using inbred mice}, volume={20}, ISSN={0938-8990 1432-1777}, url={http://dx.doi.org/10.1007/s00335-009-9199-0}, DOI={10.1007/s00335-009-9199-0}, number={7}, journal={Mammalian Genome}, publisher={Springer Science and Business Media LLC}, author={Gatti, Daniel M. and Harrill, Alison H. and Wright, Fred A. and Threadgill, David W. and Rusyn, Ivan}, year={2009}, month={Jul}, pages={437–446} } @article{lee_sullivan_zou_wright_2008, title={Comment on a Simple and Improved Correction for Population Stratification}, volume={82}, ISSN={0002-9297}, url={http://dx.doi.org/10.1016/j.ajhg.2007.10.014}, DOI={10.1016/j.ajhg.2007.10.014}, number={2}, journal={The American Journal of Human Genetics}, publisher={Elsevier BV}, author={Lee, Seunggeun and Sullivan, Patrick F. and Zou, Fei and Wright, Fred A.}, year={2008}, month={Feb}, pages={524–526} } @article{ghosh_zou_wright_2008, title={Estimating Odds Ratios in Genome Scans: An Approximate Conditional Likelihood Approach}, volume={82}, ISSN={0002-9297}, url={http://dx.doi.org/10.1016/j.ajhg.2008.03.002}, DOI={10.1016/j.ajhg.2008.03.002}, number={5}, journal={The American Journal of Human Genetics}, publisher={Elsevier BV}, author={Ghosh, Arpita and Zou, Fei and Wright, Fred A.}, year={2008}, month={May}, pages={1064–1074} } @article{ghosh_zou_wright_2008, title={Estimating Odds Ratios in Genome Scans: An Approximate Conditional Likelihood Approach}, volume={82}, ISSN={0002-9297}, url={http://dx.doi.org/10.1016/j.ajhg.2008.04.004}, DOI={10.1016/j.ajhg.2008.04.004}, number={5}, journal={The American Journal of Human Genetics}, publisher={Elsevier BV}, author={Ghosh, Arpita and Zou, Fei and Wright, Fred A.}, year={2008}, month={May}, pages={1224} } @article{sullivan_lin_tzeng_van den oord_perkins_stroup_wagner_lee_wright_zou_et al._2008, title={Genomewide association for schizophrenia in the CATIE study: results of stage 1}, volume={13}, ISSN={1359-4184 1476-5578}, url={http://dx.doi.org/10.1038/mp.2008.25}, DOI={10.1038/mp.2008.25}, number={6}, journal={Molecular Psychiatry}, publisher={Springer Science and Business Media LLC}, author={Sullivan, P F and Lin, D and Tzeng, J-Y and van den Oord, E and Perkins, D and Stroup, T S and Wagner, M and Lee, S and Wright, F A and Zou, F and et al.}, year={2008}, month={Mar}, pages={570–584} } @article{drumm_konstan_schluchter_handler_pace_zou_zariwala_fargo_xu_dunn_et al._2005, title={Genetic Modifiers of Lung Disease in Cystic Fibrosis}, volume={353}, ISSN={0028-4793 1533-4406}, url={http://dx.doi.org/10.1056/NEJMoa051469}, DOI={10.1056/NEJMoa051469}, number={14}, journal={New England Journal of Medicine}, publisher={Massachusetts Medical Society}, author={Drumm, Mitchell L. and Konstan, Michael W. and Schluchter, Mark D. and Handler, Allison and Pace, Rhonda and Zou, Fei and Zariwala, Maimoona and Fargo, David and Xu, Airong and Dunn, John M. and et al.}, year={2005}, month={Oct}, pages={1443–1453} } @article{graham_virtaneva_porcella_barry_gowen_johnson_wright_musser_2005, title={Group A Streptococcus Transcriptome Dynamics during Growth in Human Blood Reveals Bacterial Adaptive and Survival Strategies}, volume={166}, ISSN={0002-9440}, url={http://dx.doi.org/10.1016/S0002-9440(10)62268-7}, DOI={10.1016/S0002-9440(10)62268-7}, number={2}, journal={The American Journal of Pathology}, publisher={Elsevier BV}, author={Graham, Morag R. and Virtaneva, Kimmo and Porcella, Stephen F. and Barry, William T. and Gowen, Brian B. and Johnson, Claire R. and Wright, Fred A. and Musser, James M.}, year={2005}, month={Feb}, pages={455–465} }