Fang Chen

Works (8)

Updated: July 13th, 2023 21:19

2017 journal article

Molecular machines open cell membranes

Nature, 548(7669), 567–572.

By: V. García-López *, F. Chen n, L. Nilewski *, G. Duret *, A. Aliyan *, A. Kolomeisky*, J. Robinson *, G. Wang n, R. Pal *, J. Tour *

MeSH headings : Animals; Cell Membrane / chemistry; Cell Membrane / metabolism; Cell Survival; Diffusion; HEK293 Cells; Humans; Infrared Rays; Lipid Bilayers / chemistry; Lipid Bilayers / metabolism; Mice; Molecular Motor Proteins / metabolism; Molecular Motor Proteins / radiation effects; Movement / radiation effects; NIH 3T3 Cells; Nanotechnology; Necrosis; Patch-Clamp Techniques; Photons; Rotation; Ultraviolet Rays
TL;DR: Molecular machines can drill through cellular bilayers using their molecular-scale actuation, specifically nanomechanical action and it is expected that molecular machines could also be used in vivo, especially as their design progresses to allow two-photon, near-infrared and radio-frequency activation. (via Semantic Scholar)
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Added: August 6, 2018

2016 journal article

Imaging Single Molecular Machines Attached with Two BODIPY Dyes at the Air-Solid Interface: High Probability of Single-Step-Like Photobleaching and Nonscaling Intensity

JOURNAL OF PHYSICAL CHEMISTRY C, 120(46), 26522–26531.

By: T. Jin n, V. Garcia-Lopez *, F. Chen n, J. Tour * & G. Wang n

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Source: Web Of Science
Added: August 6, 2018

2016 journal article

Investigating axial diffusion in cylindrical pores using confocal single-particle fluorescence correlation spectroscopy

ELECTROPHORESIS, 37(15-16), 2129–2138.

By: F. Chen n, B. Neupane n, P. Li n, W. Su  n & G. Wang n

author keywords: Confined diffusion; Confocal fluorescence microscopy; Cylindrical nanopores; Fluorescence correlation spectroscopy
MeSH headings : Diffusion; Hydrodynamics; Models, Theoretical; Molecular Dynamics Simulation; Nanoparticles / chemistry; Porosity; Spectrometry, Fluorescence / methods
TL;DR: The feasibility of using confocal fluorescence correlation spectroscopy to study small nanoparticle diffusion in hundred‐nanometer‐sized cylindrical pores is explored and two diffusion dynamics can be observed in both original intensity traces and the autocorrelation functions (ACFs). (via Semantic Scholar)
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Added: August 6, 2018

2016 journal article

Microscopic Movement of Slow-Diffusing Nanoparticles in Cylindrical Nanopores Studied with Three-Dimensional Tracking

ANALYTICAL CHEMISTRY, 88(10), 5122–5130.

By: L. Zhao n, Y. Zhong n, Y. Wei n, N. Ortiz n, F. Chen n & G. Wang n

TL;DR: This study shows that it is possible to differentiate slow diffusion in confined environments caused by different mechanisms, and that the particles in sticky pores are microscopically active by showing limited reduction of step sizes. (via Semantic Scholar)
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Added: August 6, 2018

2016 journal article

Moving Kinetics of Nanocars with Hydrophobic Wheels on Solid Surfaces at Ambient Conditions

JOURNAL OF PHYSICAL CHEMISTRY C, 120(20), 10887–10894.

By: F. Chen n, V. Garcia-Lopez *, T. Jin n, B. Neupane n, P. Chu*, J. Tour *, G. Wang n

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Added: August 6, 2018

2016 journal article

Nanosecond Time-Resolution Study of Gold Nanorod Rotation at the Liquid-Solid Interface

CHEMPHYSCHEM, 17(14), 2218–2224.

By: B. Neupane n, F. Chen n, Y. Wei n, N. Fang *, F. Ligler n & G. Wang n

author keywords: adsorption; fluctuation correlation spectroscopy; gold nanorods; rotation; surface plasmon resonance
TL;DR: This nanosecond time-resolution study reveals that the apparent continuous rotation of gold nanorods actually consists of numerous fast, intermittent rotations or transitions between a small number of weakly immobilized states, with the particle resting in the immobilization states most of the time. (via Semantic Scholar)
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Added: August 6, 2018

2015 journal article

Unimolecular Submersible Nanomachines. Synthesis, Actuation, and Monitoring

NANO LETTERS, 15(12), 8229–8239.

By: V. Garcia-Lopez, P. Chiang, F. Chen n, G. Ruan, A. Marti, A. Kolomeisky, G. Wang n, J. Tour

author keywords: Unimolecular submersible nanomachines; light-driven motor; diffusion coefficient; fluorophores
MeSH headings : Fluorescent Dyes; Nanotechnology; Spectrometry, Fluorescence / methods; Ultraviolet Rays
TL;DR: Through careful design of control molecules with no motor and with a slow motor, it is found using single molecule fluorescence correlation spectroscopy that only the molecules with fast rotating speed show an enhancement in diffusion by 26% when the motor is fully activated by UV light. (via Semantic Scholar)
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Added: August 6, 2018

2013 journal article

Tuning donut profile for spatial resolution in stimulated emission depletion microscopy

Review of Scientific Instruments, 84(4).

By: B. Neupane, F. Chen, W. Sun, D. Chiu & G. Wang

Source: NC State University Libraries
Added: August 6, 2018

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