Fred Gould

Exploring the value of a global gene drive project registry

Taitingfong, R. I., Triplett, C., Vasquez, V. N., Rajagopalan, R. M., Raban, R., Roberts, A., … Bloss, C. S. (2022, December 15). NATURE BIOTECHNOLOGY, Vol. 12.

Genes drive organisms and slippery slopes

Resnik, D. B., Medina, R. F., Gould, F., Church, G., & Kuzma, J. (2022, December 23). PATHOGENS AND GLOBAL HEALTH, Vol. 12.

Impact of Caterpillar Increased Feeding Rates on Reduction of Bt Susceptibility

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(23).

Genome evolution in an agricultural pest following adoption of transgenic crops

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 118(52).

Mathematical modeling of genetic pest management through female-specific lethality: Is one locus better than two?

EVOLUTIONARY APPLICATIONS, 14(6), 1612–1622.

Population genomics of invasive rodents on islands: Genetic consequences of colonization and prospects for localized synthetic gene drive

EVOLUTIONARY APPLICATIONS, 14(5), 1421–1435.

Rapid evolution of knockdown resistance haplotypes in response to pyrethroid selection in Aedes aegypti

Baltzegar, J., Vella, M., Gunning, C., Vasquez, G., Astete, H., Stell, F., … Gould, F. (2021, July 9). EVOLUTIONARY APPLICATIONS, Vol. 7.

Gene Drive Dynamics in Natural Populations: The Importance of Density Dependence, Space, and Sex

ANNUAL REVIEW OF ECOLOGY, EVOLUTION, AND SYSTEMATICS, VOL 51, 2020, Vol. 51, pp. 505–531.

Keeping up with the fast-moving world of crisis management

Rice, C. W., Schoen, R., Aristidou, A., Burgess, S. C., Capalbo, S., Czarnecki-Maulden, G., … Sample, V. A. (2020, September). AGRICULTURE AND HUMAN VALUES, Vol. 37, pp. 531–533.

The impact of local population genetic background on the spread of the selfish element Medea-1 in red flour beetles

ECOLOGY AND EVOLUTION, 10(2), 863–874.

Genome Editing, Gene Drives, and Synthetic Biology: Will They Contribute to Disease-Resistant Crops, and Who Will Benefit?

ANNUAL REVIEW OF PHYTOPATHOLOGY, VOL 57, 2019, Vol. 57, pp. 165–188.

Locally Fixed Alleles: A method to localize gene drive to island populations

SCIENTIFIC REPORTS, 9.

Pest management by genetic addiction

Gould, F., Dhole, S., & Lloyd, A. L. (2019, March 26). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 116, pp. 5849–5851.

Promises and perils of gene drives: Navigating the communication of complex, post-normal science

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 116(16), 7692–7697.

Science Breakthroughs to Advance Food and Agricultural Research by 2030

In SCIENCE BREAKTHROUGHS TO ADVANCE FOOD AND AGRICULTURAL RESEARCH BY 2030 (pp. 1–228).

Tethered homing gene drives: A new design for spatially restricted population replacement and suppression

EVOLUTIONARY APPLICATIONS, 12(8), 1688–1702.

The distribution and spread of naturally occurring Medea selfish genetic elements in the United States

ECOLOGY AND EVOLUTION, 9(24), 14407–14416.

A roadmap for gene drives: using institutional analysis and development to frame research needs and governance in a systems context

Journal of Responsible Innovation, 5(S1), S13–S39.

Contemporary evolution of a Lepidopteran species, Heliothis virescens, in response to modern agricultural practices

MOLECULAR ECOLOGY, 27(1), 167–181.

Efficacy of Aedes aegypti control by indoor Ultra Low Volume (ULV) insecticide spraying in Iquitos, Peru

PLOS Neglected Tropical Diseases, 12(4), e0006378.

Invasion and migration of spatially self-limiting gene drives: A comparative analysis

Evolutionary Applications, 11(5), 794–808.

The genetic architecture of ecological adaptation: intraspecific variation in host plant use by the lepidopteran crop pest Chloridea virescens

HEREDITY, 120(3), 234–250.

Wicked evolution: Can we address the sociobiological dilemma of pesticide resistance?

Science, 360(6390), 728–732.

‘Mapping research and governance needs for gene drives’

‘Mapping research and governance needs for gene drives.’ Journal of Responsible Innovation, 5(sup1), S4–S12.

Agricultural production: assessment of the potential use of Cas9-mediated gene drive systems for agricultural pest control

Journal of Responsible Innovation, 5(sup1), S98–S120.

Elevating the conversation about GE crops

Nature Biotechnology, 35(4), 302–304.

Evaluating strategies for reversing CRISPR-Cas9 gene drives

Scientific Reports, 7(1).

Application of a dense genetic map for assessment of genomic responses to selection and inbreeding in Heliothis virescens

INSECT MOLECULAR BIOLOGY, 25(4), 385–400.

Comparison of two detailed models of Aedes aegypti population dynamics

Ecosphere, 7(10), e01515.

Integrating Transgenic Vector Manipulation with Clinical Interventions to Manage Vector-Borne Diseases

PLOS Computational Biology, 12(3), e1004695.

A Critical Assessment of Vector Control for Dengue Prevention

[Review of ]. PLOS NEGLECTED TROPICAL DISEASES, 9(5).

Generation of a Transcriptome in a Model Lepidopteran Pest, Heliothis virescens, Using Multiple Sequencing Strategies for Profiling Midgut Gene Expression

PLOS ONE, 10(6).

Monitoring cotton bollworm resistance to Cry1Ac in two counties of northern China during 2009-2013

PEST MANAGEMENT SCIENCE, 71(3), 377–382.

The next generation of rodent eradications: Innovative technologies and tools to improve species specificity and increase their feasibility on islands

BIOLOGICAL CONSERVATION, 185, 47–58.

Feasible Introgression of an Anti-pathogen Transgene into an Urban Mosquito Population without Using Gene-Drive

PLOS NEGLECTED TROPICAL DISEASES, 8(7).

Genetic control of invasive fish: technological options and its role in integrated pest management

BIOLOGICAL INVASIONS, 16(6), 1201–1216.

Within-population variability in a moth sex pheromone blend: genetic basis and behavioural consequences

Proceedings of the Royal Society B: Biological Sciences, 281(1779), 20133054.

A Reduce and Replace Strategy for Suppressing Vector-Borne Diseases: Insights from a Deterministic Model

PLOS ONE, 8(9).

Diminishing Returns from Increased Percent Bt Cotton: The Case of Pink Bollworm

PLOS ONE, 8(7).

Field Cage Studies and Progressive Evaluation of Genetically-Engineered Mosquitoes

PLOS NEGLECTED TROPICAL DISEASES, 7(1).

Modeling the Dynamics of a Non-Limited and a Self-Limited Gene Drive System in Structured Aedes aegypti Populations

PLoS ONE, 8(12), e83354.

One quantitative trait locus for intra‐ and interspecific variation in a sex pheromone

Molecular Ecology, 22(4), 1065–1080.

Regulation of Aedes aegypti Population Dynamics in Field Systems: Quantifying Direct and Delayed Density Dependence

The American Journal of Tropical Medicine and Hygiene, 89(1), 68–77.

Specificity of the receptor for the major sex pheromone component in Heliothis virescens

Journal of Insect Science (Tucson, AZ), 13.

THE IMPORTANCE OF MOSQUITO BEHAVIOURAL ADAPTATIONS TO MALARIA CONTROL IN AFRICA

[Review of ]. EVOLUTION, 67(4), 1218–1230.

An Experimental Field Study of Delayed Density Dependence in Natural Populations of Aedes albopictus

PLOS ONE, 7(4).

Assessing the Feasibility of Controlling Aedes aegypti with Transgenic Methods: A Model-Based Evaluation

PLoS ONE, 7(12), e52235.

Stochasticity in Sexual Selection Enables Divergence: Implications for Moth Pheromone Evolution

[Review of ]. EVOLUTIONARY BIOLOGY, 39(2), 271–281.

THE GENETIC ARCHITECTURE OF A COMPLEX ECOLOGICAL TRAIT: HOST PLANT USE IN THE SPECIALIST MOTH, HELIOTHIS SUBFLEXA

EVOLUTION, 66(11), 3336–3351.

Assessing the impact of density dependence in field populations of Aedes aegypti

JOURNAL OF VECTOR ECOLOGY, 36(2), 300–307.

Differential expression of odorant receptor genes involved in the sexual isolation of two Heliothis moths

INSECT MOLECULAR BIOLOGY, 20(1), 115–124.

Evaluation of Location-Specific Predictions by a Detailed Simulation Model of Aedes aegypti Populations

PLoS ONE, 6(7), e22701.

Field Observations of Oviposition by a Specialist Herbivore on Plant Parts and Plant Species Unsuitable as Larval Food

Environmental Entomology, 40(6), 1478–1486.

Reduced Levels of Membrane-Bound Alkaline Phosphatase Are Common to Lepidopteran Strains Resistant to Cry Toxins from Bacillus thuringiensis

PLOS ONE, 6(3).

Susceptibility of Helicoverpa armigera from different host plants in northern China to Bacillus thuringiensis toxin Cry1Ac

CROP PROTECTION, 30(11), 1421–1424.

Age and Mating Status Do Not Affect Transcript Levels of Odorant Receptor Genes in Male Antennae of Heliothis virescens and Heliothis subflexa

JOURNAL OF CHEMICAL ECOLOGY, 36(11), 1226–1233.

Functional characterization of pheromone receptors in the tobacco budworm Heliothis virescens

Insect Molecular Biology, 20(1), 125–133.

Gene-drive into insect populations with age and spatial structure: a theoretical assessment

Evolutionary Applications, 4(3), 415–428.

Insect oviposition behavior affects the evolution of adaptation to Bt crops: consequences for refuge policies

EVOLUTIONARY ECOLOGY, 24(5), 1017–1030.

Medea selfish genetic elements as tools for altering traits of wild populations: A theoretical analysis.

Evolution, 65(4), 1149–1162.

Modeling the population dynamics of cotton bollworm Helicoverpa armigera (Hubner) (Lepidoptera: Noctuidae) over a wide area in northern China

ECOLOGICAL MODELLING, 221(15), 1819–1830.

Offspring From Sequential Matings Between Bacillus thuringiensis-Resistant and Bacillus thuringiensis-Susceptible Heliothis virescens Moths (Lepidoptera: Noctuidae)

JOURNAL OF ECONOMIC ENTOMOLOGY, 103(3), 861–868.

Sexual isolation of male moths explained by a single pheromone response QTL containing four receptor genes

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(19), 8660–8665.

Understanding Uncertainties in Model-Based Predictions of Aedes aegypti Population Dynamics

PLoS Neglected Tropical Diseases, 4(9), e830.

Vip3Aa Tolerance Response of Helicoverpa armigera Populations From a Cry1Ac Cotton Planting Region

JOURNAL OF ECONOMIC ENTOMOLOGY, 103(6), 2169–2173.

Cry2Ab Tolerance Response of Helicoverpa armigera (Lepidoptera: Noctuidae) Populations From Cry1Ac Cotton Planting Region

JOURNAL OF ECONOMIC ENTOMOLOGY, 102(3), 1217–1223.

Density-Dependent Intraspecific Competition in the Larval Stage of Aedes aegypti (Diptera: Culicidae): Revisiting the Current Paradigm

JOURNAL OF MEDICAL ENTOMOLOGY, 46(3), 409–419.

Effect of Heliothis subflexa herbivory on fruit abscission by Physalis species: the roles of mechanical damage and chemical factors

ECOLOGICAL ENTOMOLOGY, 34(5), 603–613.

Frequency of Bt Resistance Alleles in H-armigera During 2006-2008 in Northern China

ENVIRONMENTAL ENTOMOLOGY, 38(4), 1336–1342.

Fruit abscission by Physalis species as defense against frugivory

ENTOMOLOGIA EXPERIMENTALIS ET APPLICATA, 130(1), 21–27.

GEOGRAPHIC AND TEMPORAL VARIATION IN MOTH CHEMICAL COMMUNICATION

[Review of ]. EVOLUTION, 63(8), 1987–2003.

Gene-drive in age-structured insect populations

Evolutionary Applications, 2(2), 143–159.

QTL analysis of sex pheromone blend differences between two closely related moths: Insights into divergence in biosynthetic pathways

INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 39(8), 568–577.

Response of Heliothis virescens (Lepidoptera: Noctuidae) Strains to Bacillus thuringiensis Cry1Ac Incorporated Into Different Insect Artificial Diets

JOURNAL OF ECONOMIC ENTOMOLOGY, 102(4), 1599–1606.

Skeeter Buster: A Stochastic, Spatially Explicit Modeling Tool for Studying Aedes aegypti Population Replacement and Population Suppression Strategies

PLoS Neglected Tropical Diseases, 3(9), e508.

A Killer-Rescue system for self-limiting gene drive of anti-pathogen constructs

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES, 275(1653), 2823–2829.

An empirical test of the F(2) screen for detection of Bacillus thuringiensis-resistance alleles in tobacco budworm (Lepidoptera : Noctuidae)

JOURNAL OF ECONOMIC ENTOMOLOGY, 101(4), 1406–1414.

Broadening the application of evolutionarily based genetic pest management

EVOLUTION, 62(2), 500–510.

Impact of Herbivore-induced Plant Volatiles on Parasitoid Foraging Success: A Spatial Simulation of the Cotesia rubecula, Pieris rapae, and Brassica oleracea System

Journal of Chemical Ecology, 34(7), 959–970.

Limitations of stable carbon isotope analysis for determining natal host origins of tobacco budworm, Heliothis virescens

ENTOMOLOGIA EXPERIMENTALIS ET APPLICATA, 126(1), 46–52.

The Impact of Herbivore-Induced Plant Volatiles on Parasitoid Foraging Success: A General Deterministic Model

Journal of Chemical Ecology, 34(7), 945–958.

A polymerase chain reaction screen of field populations of Heliothis virescens for a retrotransposon insertion conferring resistance to Bacillus thuringiensis toxin

JOURNAL OF ECONOMIC ENTOMOLOGY, 100(1), 187–194.

Cross-resistance responses of Cry1Ac-selected Heliothis virescens (Lepidoptera : Noctuidae) to the Bacillus thuringiensis protein Vip3A

JOURNAL OF ECONOMIC ENTOMOLOGY, 100(1), 180–186.

Differential attraction of Heliothis subflexa males to synthetic pheromone lures in eastern US and western Mexico

JOURNAL OF CHEMICAL ECOLOGY, 33(2), 353–368.

Increasing tolerance to Cry1Ac cotton from cotton bollworm, Helicoverpa armigera, was confirmed in Bt cotton farming area of China

ECOLOGICAL ENTOMOLOGY, 32(4), 366–375.

Introducing desirable transgenes into insect populations using Y-linked meiotic drive - A theoretical assessment

EVOLUTION, 61(4), 717–726.

Introducing transgenes into insect populations using combined gene-drive strategies: Modeling and analysis

INSECT BIOCHEMISTRY AND MOLECULAR BIOLOGY, 37(10), 1054–1063.

The diversity of Bt resistance genes in species of Lepidoptera

Heckel, D. G., Gahan, L. J., Baxter, S. W., Zhao, J.-Z., Shelton, A. M., Gould, F., & Tabashnik, B. E. (2007, July). JOURNAL OF INVERTEBRATE PATHOLOGY, Vol. 95, pp. 192–197.

Experimental evidence for interspecific directional selection on moth pheromone communication

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 103(15), 5858–5863.

Gene drive systems for insect disease vectors

[Review of ]. NATURE REVIEWS GENETICS, 7(6), 427–435.

Genetic strategies for controlling mosquito-borne diseases

AMERICAN SCIENTIST, 94(3), 238–246.

Genetic variation for resistance to Bacillus thuringiensis toxins in Helicoverpa zea (Lepidoptera : Noctuidae) in eastern North Carolina

Journal of Economic Entomology, 99(5), 1790–1797.

Genetically engineered underdominance for manipulation of pest populations: A deterministic model

GENETICS, 172(4), 2613–2620.

Genetics of sex pheromone blend differences between Heliothis virescens and Heliothis subflexa: a chromosome mapping approach

JOURNAL OF EVOLUTIONARY BIOLOGY, 19(2), 600–617.

Impact of small fitness costs on pest adaptation to crop varieties with multiple toxins: A heuristic model

Journal of Economic Entomology, 99(6), 2091–2099.

Effect of PBAN on pheromone production by mated Heliothis virescens and Heliothis subflexa females

JOURNAL OF CHEMICAL ECOLOGY, 31(1), 14–28.

Genetic basis of resistance to Cry1Ac and Cry2Aa in Heliothis virescens (Lepidoptera : Noctuidae)

JOURNAL OF ECONOMIC ENTOMOLOGY, 98(4), 1357–1368.

Male and female antennal responses in Heliothis virescens and H subflexa to conspecific and heterospecific sex pheromone compounds

ENVIRONMENTAL ENTOMOLOGY, 34(2), 256–263.

Pest control by genetic manipulation of sex ratio

Journal of Economic Entomology, 98(1), 18–34.

Predation of Colorado potato beetle eggs by a polyphagous ladybeetle in the presence of alternate prey: potential impact on resistance evolution

ENTOMOLOGIA EXPERIMENTALIS ET APPLICATA, 114(1), 47–54.

Transposable element insertion location bias and the dynamics of gene drive in mosquito populations

INSECT MOLECULAR BIOLOGY, 14(5), 493–500.

Comparative production of Helicoverpa zea (Lepidoptera : Noctuidae) from transgenic cotton expressing either one or two Bacillus thuringiensis proteins with and without insecticide oversprays

JOURNAL OF ECONOMIC ENTOMOLOGY, 97(5), 1719–1725.

Delaying evolution of insect resistance to transgenic crops by decreasing dominance and heritability

JOURNAL OF EVOLUTIONARY BIOLOGY, 17(4), 904–912.

Frequency of Bt resistance genes in Helicoverpa armigera populations from the Yellow River cotton-farming region of China

ENTOMOLOGIA EXPERIMENTALIS ET APPLICATA, 112(2), 135–143.

Introgressing pheromone QTL between species: Towards an evolutionary understanding of differentiation in sexual communication

Journal of Chemical Ecology, 30(12), 2495–2514.

Population genetics of autocidal control and strain replacement

[Review of ]. ANNUAL REVIEW OF ENTOMOLOGY, 49, 193–217.

The HevCaLP protein mediates binding specificity of the Cry1A class of Bacillus thuringiensis toxins in Heliothis virescens

BIOCHEMISTRY, 43(44), 14299–14305.

Bt-resistance management - theory meets data

Gould, F. (2003, December). NATURE BIOTECHNOLOGY, Vol. 21, pp. 1450–1451.

Dual resistance to Bacillus thuringiensis Cry1Ac and Cry2Aa toxins in Heliothis virescens suggests multiple mechanisms of resistance

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 69(10), 5898–5906.

Estimated frequency of nonrecessive Bt resistance genes in bollworm, Helicoverpa zea (Boddie) (Lepidoptera : Noctuidae) in eastern North Carolina

JOURNAL OF ECONOMIC ENTOMOLOGY, 96(1), 137–142.

Insecticide resistance assay

Washington, DC: U.S. Patent and Trademark Office.

Sensitivity analysis of a spatially-explicit stochastic simulation model of the evolution of resistance in Helicoverpa zea (Lepidoptera : Noctuidae) to Bt transgenic corn and cotton

JOURNAL OF ECONOMIC ENTOMOLOGY, 96(1), 173–187.

Spatial processes in the evolution of resistance in Helicoverpa zea (Lepidoptera : Noctuidae) to Bt transgenic corn and cotton in a mixed agroecosystem: a biology-rich stochastic simulation model

JOURNAL OF ECONOMIC ENTOMOLOGY, 96(1), 156–172.

Altered glycosylation of 63- and 68-kilodalton microvillar proteins in Heliothis virescens correlates with reduced Cry1 toxin binding, decreased pore formation, and increased resistance to Bacillus thuringiensis Cry1 toxins

APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 68(11), 5711–5717.

Bacillus thuringiensis-toxin resistance management: Stable isotope assessment of alternate host use by Helicoverpa zea

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 99(26), 16581–16586.

Behavioral adaptations increase the value of enemy-free space for Heliothis subflexa, a specialist herbivore.

Evolution, 56(4), 679–689.

Is attraction fatal? The effects of herbivore-induced plant volatiles on herbivore parasitism

ECOLOGY, 83(12), 3416–3425.

Genetic analysis of larval survival and larval growth of two populations of Leptinotarsa decemlineata on tomato

ENTOMOLOGIA EXPERIMENTALIS ET APPLICATA, 99(2), 143–155.

Identification of a gene associated with bit resistance in Heliothis virescens

SCIENCE, 293(5531), 857–860.

Species diagnosis and Bacillus thuringiensis resistance monitoring of Heliothis virescens and Helicoverpa zea (Lepidoptera : noctuidae) field strains from the southern United States using feeding disruption bioassays

JOURNAL OF ECONOMIC ENTOMOLOGY, 94(1), 76–85.

Bacillus thuringiensis delta-endotoxin proteins show a correlation in toxicity and short circuit current inhibition against Helicoverpa zea

CURRENT MICROBIOLOGY, 41(3), 214–219.

Detection of resistant insects and IPM

Emerging Technologies for Integrated Pest Management : Concepts, Research, and Implementation, 67.

Determination of receptor binding properties of Bacillus thuringiensis delta-endotoxins to cotton bollworm (Helicoverpa zea) and pink bollworm (Pectinophora gossypiella) midgut brush border membrane vesicles

PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 67(3), 198–216.

Dispersal by larvae of the stem borers Scirpophaga incertulas (Lepidoptera : Pyralidae) and Chilo suppressalis (Lepidoptera : Crambidae) in plots of transplanted rice

ENVIRONMENTAL ENTOMOLOGY, 29(5), 958–971.

Frequency of alleles conferring resistance to a Bacillus thuringiensis toxin in a Philippine population of Scirpophaga incertulas (Lepidoptera : Pyralidae)

JOURNAL OF ECONOMIC ENTOMOLOGY, 93(5), 1515–1521.

Heritability of tolerance to the Cry1Ab toxin of Bacillus thuringiensis in Chilo suppressalis (Lepidoptera : Crambidae)

JOURNAL OF ECONOMIC ENTOMOLOGY, 93(1), 14–17.