Frances Ligler

Moatti, A., Connard, S., De Britto, N., Dunn, W. A., Rastogi, S., Rai, M., … Greenbaum, A. (2024). Surgical procedure of intratympanic injection and inner ear pharmacokinetics simulation in domestic pigs. FRONTIERS IN PHARMACOLOGY, 15. https://doi.org/10.3389/fphar.2024.1348172

Moatti, A., Silkstone, D., Martin, T., Abbey, K., Hutson, K. A., Fitzpatrick, D. C., … Greenbaum, A. (2023). Assessment of drug permeability through an ex vivo porcine round window membrane model. ISCIENCE, 26(6). https://doi.org/10.1016/j.isci.2023.106789

Overchuk, M., Ruhi, M. K., Rickard, B., Ligler, F., & Rizvi, I. (2023). Development of a light emitting device for the treatment of peritoneal car- cinomatosis of ovarian origin by intracavitary photodynamic therapy. PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 41. https://doi.org/10.1016/j.pdpdt.2023.103406

Rickard, B. P., Overchuk, M., Tulino, J., Tan, X., Ligler, F. S., Bae-Jump, V. L., … Rizvi, I. (2023). Exposure to select PFAS and PFAS mixtures alters response to platinum-based chemotherapy in endometrial cancer cell lines. ENVIRONMENTAL HEALTH, 22(1). https://doi.org/10.1186/s12940-023-01034-2

Wang, Y., Sadeghi, S., Velayati, A., Paul, R., Hetzler, Z., Danilov, E., … Wei, Q. (2023). Low-rate smartphone videoscopy for microsecond luminescence lifetime imaging with machine learning. PNAS NEXUS, 2(10). https://doi.org/10.1093/pnasnexus/pgad313

Overchuk, M., Ruhi, M. K., Rickard, B., Ligler, F., & Rizvi, I. (2023). Targeted PDT Combinations to Overcome Fluid Shear Stress-induced Plat- inum Resistance in Ovarian Cancer. PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 41. https://doi.org/10.1016/j.pdpdt.2023.103405

Moatti, A., Cai, Y., Li, C., Popowski, K. D., Cheng, K., Ligler, F. S., & Greenbaum, A. (2023). Tissue clearing and three-dimensional imaging of the whole cochlea and vestibular system from multiple large-animal models. STAR PROTOCOLS, 4(2). https://doi.org/10.1016/j.xpro.2023.102220

Agarwalla, P., Ogunnaike, E. A., Ahn, S., Froehlich, K. A., Jansson, A., Ligler, F. S., … Brudno, Y. (2022, March 24). Bioinstructive implantable scaffolds for rapid in vivo manufacture and release of CAR-T cells. NATURE BIOTECHNOLOGY, Vol. 3. https://doi.org/10.1038/s41587-022-01245-x

Hetzler, Z., Wang, Y., Krafft, D., Jamalzadegan, S., Overton, L., Kudenov, M. W., … Wei, Q. (2022). Flexible sensor patch for continuous carbon dioxide monitoring. FRONTIERS IN CHEMISTRY, 10. https://doi.org/10.3389/fchem.2022.983523

Lee, G.-hun, Huang, S. A., Aw, W. Y., Rathod, M. L., Cho, C., Ligler, F. S., & Polacheck, W. J. (2022). Multilayer microfluidic platform for the study of luminal, transmural, and interstitial flow. BIOFABRICATION, 14(2). https://doi.org/10.1088/1758-5090/ac48e5

Moatti, A., Li, C., Sivadanam, S., Cai, Y., Ranta, J., Piedrahita, J. A., … Greenbaum, A. (2022). Ontogeny of cellular organization and LGR5 expression in porcine cochlea revealed using tissue clearing and 3D imaging. ISCIENCE, 25(8). https://doi.org/10.1016/j.isci.2022.104695

Carter, A., Popowski, K., Cheng, K., Greenbaum, A., Ligler, F. S., & Moatti, A. (2021, September 24). Enhancement of Bone Regeneration Through the Converse Piezoelectric Effect, A Novel Approach for Applying Mechanical Stimulation. BIOELECTRICITY, Vol. 9. https://doi.org/10.1089/bioe.2021.0019

Ogunnaike, E. A., Valdivia, A., Yazdimamaghani, M., Leon, E., Nandi, S., Hudson, H., … Dotti, G. (2021). Fibrin gel enhances the antitumor effects of chimeric antigen receptor T cells in glioblastoma. SCIENCE ADVANCES, 7(41). https://doi.org/10.1126/sciadv.abg5841

Martins, A. M. G., Wilkins, M. D., Ligler, F. S., Daniele, M. A., & Freytes, D. O. (2021). Microphysiological System for High-Throughput Computer Vision Measurement of Microtissue Contraction. ACS SENSORS, 6(3), 985–994. https://doi.org/10.1021/acssensors.0c02172

Giri, B., Pandey, S., Shrestha, R., Pokharel, K., Ligler, F. S., & Neupane, B. B. (2021). [Review of Review of analytical performance of COVID-19 detection methods]. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 413(1), 35–48. https://doi.org/10.1007/s00216-020-02889-x

Roosa, C. A., Muhamed, I., Young, A. T., Nellenbach, K., Daniele, M. A., Ligler, F. S., & Brown, A. C. (2021). Synthesis of sonicated fibrin nanoparticles that modulate fibrin clot polymerization and enhance angiogenic responses. COLLOIDS AND SURFACES B-BIOINTERFACES, 204. https://doi.org/10.1016/j.colsurfb.2021.111805

Su, T., Huang, K., Mathews, K. G., Scharf, V. F., Hu, S., Li, Z., … Cheng, K. (2020). Cardiac Stromal Cell Patch Integrated with Engineered Microvessels Improves Recovery from Myocardial Infarction in Rats and Pigs. ACS BIOMATERIALS SCIENCE & ENGINEERING, 6(11), 6309–6320. https://doi.org/10.1021/acsbiomaterials.0c00942

Shirwaiker, R. A., Fisher, M. B., Anderson, B., Schuchard, K. G., Warren, P. B., Maze, B., … Pourdeyhimi, B. (2020). High-Throughput Manufacture of 3D Fiber Scaffolds for Regenerative Medicine. TISSUE ENGINEERING PART C-METHODS, 26(7), 364–374. https://doi.org/10.1089/ten.tec.2020.0098

Griffith, C. M., Huang, S. A., Cho, C., Khare, T. M., Rich, M., Lee, G.-hun, … Polacheck, W. J. (2020). Microfluidics for the study of mechanotransduction. JOURNAL OF PHYSICS D-APPLIED PHYSICS, 53(22). https://doi.org/10.1088/1361-6463/ab78d4

Agarwalla, P., Ogunnaike, E. A., Ahn, S., Ligler, F. S., Dotti, G., & Brudno, Y. (2020). Scaffold-Mediated Static Transduction of T Cells for CAR-T Cell Therapy. ADVANCED HEALTHCARE MATERIALS, 9(14). https://doi.org/10.1002/adhm.202000275

Moatti, A., Cai, Y., Li, C., Sattler, T., Edwards, L., Piedrahita, J., … Greenbaum, A. (2020). Three-dimensional imaging of intact porcine cochlea using tissue clearing and custom-built light-sheet microscopy. BIOMEDICAL OPTICS EXPRESS, 11(11), 6181–6196. https://doi.org/10.1364/BOE.402991

Su, T., Huang, K., Ma, H., Liang, H., Dinh, P.-U., Chen, J., … Cheng, K. (2019). Biomimetics: Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury (Adv. Funct. Mater. 4/2019). Advanced Functional Materials, 29(4), 1970019. https://doi.org/10.1002/ADFM.201970019

Rich, M., Mohd, O., Ligler, F. S., & Walker, G. M. (2019). Characterization of glass frit capillary pumps for microfluidic devices. MICROFLUIDICS AND NANOFLUIDICS, 23(5). https://doi.org/10.1007/s10404-019-2238-6

Muhamed, I., Sproul, E. P., Ligler, F. S., & Brown, A. C. (2019). Fibrin Nanoparticles Coupled with Keratinocyte Growth Factor Enhance the Dermal Wound-Healing Rate. ACS APPLIED MATERIALS & INTERFACES, 11(4), 3771–3780. https://doi.org/10.1021/acsami.8b21056

Ligler, F. S., & Gooding, J. J. (2019). Lighting Up Biosensors: Now and the Decade To Come. ANALYTICAL CHEMISTRY, 91(14), 8732–8738. https://doi.org/10.1021/acs.analchem.9b00793

Sotoudegan, M. S., Mohd, O., Ligler, F. S., & Walker, G. M. (2019). Paper-based passive pumps to generate controllable whole blood flow through microfluidic devices. LAB ON A CHIP, 19(22), 3787–3795. https://doi.org/10.1039/c9lc00822e

Chen, Q., Hu, Q., Dukhovlinova, E., Chen, G., Ahn, S., Wang, C., … Gu, Z. (2019). Photothermal Therapy Promotes Tumor Infiltration and Antitumor Activity of CAR T Cells. ADVANCED MATERIALS, 31(23). https://doi.org/10.1002/adma.201900192

Su, T., Huang, K., Ma, H., Liang, H., Dinh, P.-U., Chen, J., … Cheng, K. (2019). Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury. ADVANCED FUNCTIONAL MATERIALS, 29(4). https://doi.org/10.1002/adfm.201803567

Su, T., Huang, K., Daniele, M. A., Hensley, M. T., Young, A. T., Tang, J., … Cheng, K. (2018). Cardiac Stem Cell Patch Integrated with Microengineered Blood Vessels Promotes Cardiomyocyte Proliferation and Neovascularization after Acute Myocardial Infarction. ACS APPLIED MATERIALS & INTERFACES, 10(39), 33088–33096. https://doi.org/10.1021/acsami.8b13571

Ligler, F. S., & Macuare, K. A. (2018). THE NAI FELLOW PROFILE: AN INTERVIEW WITH DR. FRANCES LIGLER. TECHNOLOGY AND INNOVATION, Vol. 19, pp. 645–651. https://doi.org/10.21300/19.3.2018.645

Yu, J., Qian, C., Zhang, Y., Cui, Z., Zhu, Y., Shen, Q., … Gu, Z. (2017). Hypoxia and H2O2 Dual-Sensitive Vesicles for Enhanced Glucose-Responsive Insulin Delivery. NANO LETTERS, 17(2), 733–739. https://doi.org/10.1021/acs.nanolett.6b03848

Wang, J., Zhang, Y., Archibong, E., Ligler, F. S., & Gu, Z. (2017). Leveraging H2O2 Levels for Biomedical Applications. Advanced Biosystems, 1(9), 1700084. https://doi.org/10.1002/ADBI.201700084

DiVito, K. A., Daniele, M. A., Roberts, S. A., Ligler, F. S., & Adams, A. A. (2017). Microfabricated blood vessels undergo neoangiogenesis. BIOMATERIALS, 138, 142–152. https://doi.org/10.1016/j.biomaterials.2017.05.012

Cummins, B. M., Chinthapatla, R., Lenin, B., Ligler, F. S., & Walker, G. M. (2017). Modular pumps as programmable hydraulic batteries for microfluidic devices. TECHNOLOGY, 5(1), 21–30. https://doi.org/10.1142/s2339547817200011

Chen, Z., Wang, J., Sun, W., Archibong, E., Kahkoska, A. R., Zhang, X., … Gu, Z. (2017). Synthetic beta cells for fusion-mediated dynamic insulin secretion. Nature Chemical Biology, 14(1), 86–93. https://doi.org/10.1038/NCHEMBIO.2511

Cummins, B. M., Chinthapatla, R., Ligler, F. S., & Walker, G. M. (2017). Time-Dependent Model for Fluid Flow in Porous Materials with Multiple Pore Sizes. Analytical Chemistry, 89(8), 4377–4381. https://doi.org/10.1021/ACS.ANALCHEM.6B04717

DiVito, K. A., Daniele, M. A., Roberts, S. A., Ligler, F. S., & Adams, A. A. (2017). “Data characterizing microfabricated human blood vessels created via hydrodynamic focusing.” Data in Brief, 14, 156–162. https://doi.org/10.1016/J.DIB.2017.07.011

Taitt, C. R., Anderson, G. P., & Ligler, F. S. (2016). Evanescent wave fluorescence biosensors: Advances of the last decade. Biosensors and Bioelectronics, 76, 103–112. https://doi.org/10.1016/J.BIOS.2015.07.040

Steward, A. J., Cole, J. H., Ligler, F. S., & Loboa, E. G. (2016). Mechanical and Vascular Cues Synergistically Enhance Osteogenesis in Human Mesenchymal Stem Cells. TISSUE ENGINEERING PART A, 22(15-16), 997–1005. https://doi.org/10.1089/ten.tea.2015.0533

Roberts, S. A., DiVito, K. A., Ligler, F. S., Adams, A. A., & Daniele, M. A. (2016). Microvessel manifold for perfusion and media exchange in three-dimensional cell cultures. Biomicrofluidics, 10(5), 054109. https://doi.org/10.1063/1.4963145

Neupane, B., Chen, F., Wei, Y., Fang, N., Ligler, F. S., & Wang, G. (2016). Nanosecond Time-Resolution Study of Gold Nanorod Rotation at the Liquid-Solid Interface. CHEMPHYSCHEM, 17(14), 2218–2224. https://doi.org/10.1002/cphc.201600174

Cummins, B. M., Ligler, F. S., & Walker, G. M. (2016). Point-of-care diagnostics for niche applications. Biotechnology Advances, 34(3), 161–176. https://doi.org/10.1016/J.BIOTECHADV.2016.01.005

Giri, B., Pandey, B., Neupane, B., & Ligler, F. S. (2016). Signal amplification strategies for microfluidic immunoassays. TrAC Trends in Analytical Chemistry, 79, 326–334. https://doi.org/10.1016/J.TRAC.2015.10.021

Daniele, M. A., Boyd, D. A., Mott, D. R., & Ligler, F. S. (2015). 3D hydrodynamic focusing microfluidics for emerging sensing technologies. Biosensors and Bioelectronics, 67, 25–34. https://doi.org/10.1016/j.bios.2014.07.002

Pacardo, D. B., Neupane, B., Rikard, S. M., Lu, Y., Mo, R., Mishra, S. R., … Gu, Z. (2015). A dual wavelength-activatable gold nanorod complex for synergistic cancer treatment. NANOSCALE, 7(28), 12096–12103. https://doi.org/10.1039/c5nr01568e

Pacardo, D. B., Neupane, B., Wang, G., Gu, Z., Walker, G. M., & Ligler, F. S. (2015). A temperature microsensor for measuring laser-induced heating in gold nanorods. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 407(3), 719–725. https://doi.org/10.1007/s00216-014-8222-9

Neupane, B., Jin, T., Mellor, L. F., Loboa, E. G., Ligler, F. S., & Wang, G. F. (2015). Continuous-wave stimulated emission depletion microscope for imaging actin cytoskeleton in fixed and live cells. Sensors (Basel, Switzerland), 15(9), 24178–24190.

Daniele, M. A., Boyd, D. A., Adams, A. A., & Ligler, F. S. (2015). Microfluidic strategies for design and assembly of microfibers and nanofibers with tissue engineering and regenerative medicine applications. Advanced Healthcare Materials, 4(1).

Daniele, M. A., Boyd, D. A., Adams, A. A., & Ligler, F. S. (2015). Microfluidics: Microfluidic Strategies for Design and Assembly of Microfibers and Nanofibers with Tissue Engineering and Regenerative Medicine Applications (Adv. Healthcare Mater. 1/2015). Advanced Healthcare Materials, 4(1), 2–2. https://doi.org/10.1002/ADHM.201570002

Yu, J., Zhang, Y., Ye, Y., DiSanto, R., Sun, W., Ranson, D., … Gu, Z. (2015). Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(27), 8260–8265. https://doi.org/10.1073/pnas.1505405112

Pacardo, D. B., Ligler, F. S., & Gu, Z. (2015). [Review of Programmable nanomedicine: synergistic and sequential drug delivery systems]. NANOSCALE, 7(8), 3381–3391. https://doi.org/10.1039/c4nr07677j

Sweedler, J. V., Armstrong, D. W., Baba, Y., Desmet, G., Dovichi, N., Ewing, A., … Zhang, X. (2015). The Scope of Analytical Chemistry. Analytical Chemistry, 87(13), 6425–6425. https://doi.org/10.1021/ACS.ANALCHEM.5B02231

Lu, Y., Hu, Q., Lin, Y., Pacardo, D. B., Wang, C., Sun, W., … Gu, Z. (2015). Transformable liquid-metal nanomedicine. NATURE COMMUNICATIONS, 6(1). https://doi.org/10.1038/ncomms10066

Boyd, D. A., Naciri, J., Fontana, J., Pacardo, D. B., Shields, A. R., Verbarg, J., … Ligler, F. S. (2014). Facile Fabrication of Color Tunable Film and Fiber Nanocomposites via Thiol Click Chemistry. MACROMOLECULES, 47(2), 695–704. https://doi.org/10.1021/ma401636e

Daniele, M. A., Adams, A. A., Naciri, J., North, S. H., & Ligler, F. S. (2014). Interpenetrating networks based on gelatin methacrylamide and PEG formed using concurrent thiol click chemistries for hydrogel tissue engineering scaffolds. Biomaterials, 35(6), 1845–1856. https://doi.org/10.1016/J.BIOMATERIALS.2013.11.009

Boyd, D. A., Adams, A. A., Daniele, M. A., & Ligler, F. S. (2014). Microfluidic Fabrication of Polymeric and Biohybrid Fibers with Predesigned Size and Shape. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (83). https://doi.org/10.3791/50958

Daniele, M. A., Boyd, D. A., Adams, A. A., & Ligler, F. S. (2014). Microfluidic Strategies for Design and Assembly of Microfibers and Nanofibers with Tissue Engineering and Regenerative Medicine Applications. Advanced Healthcare Materials, 4(1), 11–28. https://doi.org/10.1002/ADHM.201400144

Daniele, M. A., Radom, K., Ligler, F. S., & Adams, A. A. (2014). Microfluidic fabrication of multiaxial microvessels via hydrodynamic shaping. RSC Adv., 4(45), 23440–23446. https://doi.org/10.1039/c4ra03667k

Neupane, B., Ligler, F. S., & Wang, G. F. (2014). [Review of Review of recent developments in stimulated emission depletion microscopy: Applications on cell imaging]. Journal of Biomedical Optics, 19(8).

Lu, Y., Mo, R., Tai, W., Sun, W., Pacardo, D. B., Qian, C., … Gu, Z. (2014). Self-folded redox/acid dual-responsive nanocarriers for anticancer drug delivery. CHEMICAL COMMUNICATIONS, 50(95), 15105–15108. https://doi.org/10.1039/c4cc07004f

Boyd, D. A., Bezares, F. J., Pacardo, D. B., Ukaegbu, M., Hosten, C., & Ligler, F. S. (2014). Small-Molecule Detection in Thiol-Yne Nanocomposites via Surface-Enhanced Raman Spectroscopy. ANALYTICAL CHEMISTRY, 86(24), 12315–12320. https://doi.org/10.1021/ac503607b

Golden, J. P., Verbarg, J., Howell, P. B., Jr., Shriver-Lake, L. C., & Ligler, F. S. (2013). Automated processing integrated with a microflow cytometer for pathogen detection in clinical matrices. Biosensors and Bioelectronics, 40(1), 10–16. https://doi.org/10.1016/j.bios.2012.08.015

Verbarg, J., Plath, W. D., Shriver-Lake, L. C., Howell, P. B., Jr., Erickson, J. S., Golden, J. P., & Ligler, F. S. (2013). Catch and Release: Integrated System for Multiplexed Detection of Bacteria. Analytical Chemistry, 85(10), 4944–4950. https://doi.org/10.1021/AC303801V

McEwen, C. N., Ligler, F. S., & Swager, T. M. (2013). Chemical and biological detection. CHEMICAL SOCIETY REVIEWS, Vol. 42, pp. 8581–8583. https://doi.org/10.1039/c3cs90078a

Boyd, D. A., Shields, A. R., Howell, P. B., & Ligler, F. S. (2013). Design and fabrication of uniquely shaped thiol–ene microfibers using a two-stage hydrodynamic focusing design. Lab on a Chip, 13(15), 3105. https://doi.org/10.1039/C3LC50413A

Daniele, M. A., North, S. H., Naciri, J., Howell, P. B., Foulger, S. H., Ligler, F. S., & Adams, A. A. (2013). Microfabrication: Rapid and Continuous Hydrodynamically Controlled Fabrication of Biohybrid Microfibers (Adv. Funct. Mater. 6/2013). Advanced Functional Materials, 23(6), 697–697. https://doi.org/10.1002/ADFM.201370031

Ligler, F. S., & White, H. S. (2013, December 3). Nanomaterials in Analytical Chemistry. ANALYTICAL CHEMISTRY, Vol. 85, pp. 11161–11162. https://doi.org/10.1021/ac403331m

Shriver-Lake, L. C., Golden, J., Bracaglia, L., & Ligler, F. S. (2013). Simultaneous assay for ten bacteria and toxins in spiked clinical samples using a microflow cytometer. Analytical and Bioanalytical Chemistry, 405(16), 5611–5614. https://doi.org/10.1007/S00216-013-6980-4

Boyd, D. A., Shields, A. R., Naciri, J., & Ligler, F. S. (2012). Hydrodynamic Shaping, Polymerization, and Subsequent Modification of Thiol Click Fibers. ACS Applied Materials & Interfaces, 5(1), 114–119. https://doi.org/10.1021/am3022834

Justin, G. A., Denisin, A. K., Nasir, M., Shriver-Lake, L. C., Golden, J. P., & Ligler, F. S. (2012). Hydrodynamic focusing for impedance-based detection of specifically bound microparticles and cells: Implications of fluid dynamics on tunable sensitivity. Sensors and Actuators B: Chemical, 166-167, 386–393. https://doi.org/10.1016/j.snb.2012.02.077

Shields, A. R., Spillmann, C. M., Naciri, J., Howell, P. B., Thangawng, A. L., & Ligler, F. S. (2012). Hydrodynamically directed multiscale assembly of shaped polymer fibers. Soft Matter, 8(24), 6656. https://doi.org/10.1039/c2sm07429j

Daniele, M. A., North, S. H., Naciri, J., Howell, P. B., Foulger, S. H., Ligler, F. S., & Adams, A. A. (2012). Rapid and Continuous Hydrodynamically Controlled Fabrication of Biohybrid Microfibers. Advanced Functional Materials, 23(6), 698–704. https://doi.org/10.1002/adfm.201202258

Verbarg, J., Kamgar-Parsi, K., Shields, A. R., Howell, P. B., & Ligler, F. S. (2012). Spinning magnetic trap for automated microfluidic assay systems. Lab on a Chip, 12(10), 1793. https://doi.org/10.1039/c2lc21189k

Justin, G., Nasir, M., & Ligler, F. S. (2011). Erratum to: Hydrodynamic and electrical considerations in the design of a four-electrode impedance-based microfluidic device. Analytical and Bioanalytical Chemistry, 400(9), 3177–3177. https://doi.org/10.1007/S00216-011-5011-6

Justin, G., Nasir, M., & Ligler, F. S. (2011). Hydrodynamic and electrical considerations in the design of a four-electrode impedance-based microfluidic device. Analytical and Bioanalytical Chemistry, 400(5), 1347–1358. https://doi.org/10.1007/S00216-011-4872-Z

Golden, J. P., Justin, G. A., Nasir, M., & Ligler, F. S. (2011). Hydrodynamic focusing—a versatile tool. Analytical and Bioanalytical Chemistry, 402(1), 325–335. https://doi.org/10.1007/S00216-011-5415-3

Erickson, J. S., Hashemi, N., Sullivan, J. M., Weidemann, A. D., & Ligler, F. S. (2011). In SituPhytoplankton Analysis: There’s Plenty of Room at the Bottom. Analytical Chemistry, 84(2), 839–850. https://doi.org/10.1021/ac201623k

Hashemi, N., Erickson, J. S., Golden, J. P., Jackson, K. M., & Ligler, F. S. (2011). Microflow Cytometer for optical analysis of phytoplankton. Biosensors and Bioelectronics, 26(11), 4263–4269. https://doi.org/10.1016/j.bios.2011.03.042

Smith, J. E., Sapsford, K. E., Tan, W., & Ligler, F. S. (2011). Optimization of antibody-conjugated magnetic nanoparticles for target preconcentration and immunoassays. Analytical Biochemistry, 410(1), 124–132. https://doi.org/10.1016/j.ab.2010.11.005

Hashemi, N., Erickson, J. S., Golden, J. P., & Ligler, F. S. (2011). Optofluidic characterization of marine algae using a microflow cytometer. Biomicrofluidics, 5(3), 032009. https://doi.org/10.1063/1.3608136

Nasir, M., Mott, D. R., Kennedy, M. J., Golden, J. P., & Ligler, F. S. (2011). Parameters affecting the shape of a hydrodynamically focused stream. Microfluidics and Nanofluidics, 11(2), 119–128. https://doi.org/10.1007/S10404-011-0778-5

Thangawng, A. L., Howell, Jr, P. B., Spillmann, C. M., Naciri, J., & Ligler, F. S. (2011). UV polymerization of hydrodynamically shaped fibers. Lab on a Chip, 11(6), 1157. https://doi.org/10.1039/c0lc00392a

Thangawng, A. L., Kim, J. S., Golden, J. P., Anderson, G. P., Robertson, K. L., Low, V., & Ligler, F. S. (2010). A hard microflow cytometer using groove-generated sheath flow for multiplexed bead and cell assays. Analytical and Bioanalytical Chemistry, 398(5), 1871–1881. https://doi.org/10.1007/S00216-010-4019-7

Hashemi, N., Howell, Jr., P. B., Erickson, J. S., Golden, J. P., & Ligler, F. S. (2010). Dynamic reversibility of hydrodynamic focusing for recycling sheath fluid. Lab on a Chip, 10(15), 1952. https://doi.org/10.1039/c004696e

Nasir, M., Price, D. T., Shriver-Lake, L. C., & Ligler, F. (2010). Effect of diffusion on impedance measurements in a hydrodynamic flow focusing sensor. Lab on a Chip, 10(20), 2787. https://doi.org/10.1039/c005257d

Nasir, M., Ateya, D. A., Burk, D., Golden, J. P., & Ligler, F. S. (2010). Hydrodynamic focusing of conducting fluids for conductivity-based biosensors. Biosensors and Bioelectronics, 25(6), 1363–1369. https://doi.org/10.1016/j.bios.2009.10.033

Lin, B., Johnson, B. J., Rubin, R. A., Malanoski, A. P., & Ligler, F. S. (2010). Iron chelation by cranberry juice and its impact on Escherichia coli growth. BioFactors, 37(2), 121–130. https://doi.org/10.1002/biof.110

Kim, J. S., Taitt, C. R., Ligler, F. S., & Anderson, G. P. (2010). Multiplexed magnetic microsphere immunoassays for detection of pathogens in foods. Sensing and Instrumentation for Food Quality and Safety, 4(2), 73–81. https://doi.org/10.1007/S11694-010-9097-X

Kim, J. S., & Ligler, F. S. (2010). Utilization of microparticles in next-generation assays for microflow cytometers. Analytical and Bioanalytical Chemistry, 398(6), 2373–2382. https://doi.org/10.1007/S00216-010-3848-8

Thangawng, A. L., Howell Jr, P. B., Richards, J. J., Erickson, J. S., & Ligler, F. S. (2009). A simple sheath-flow microfluidic device for micro/nanomanufacturing: fabrication of hydrodynamically shaped polymer fibers. Lab on a Chip, 9(21), 3126. https://doi.org/10.1039/b910581f

Ligler, F. S. (2009). Common and uncommon sense for sensingIntegrated Analytical Systems, R. Poryrailo (Ed.), Springer (2009) [Review of Common and uncommon sense for sensing Integrated Analytical Systems, R. Poryrailo (Ed.), Springer (2009), by R. Poryrailo]. Biosensors and Bioelectronics, 25(2), 537. https://doi.org/10.1016/j.bios.2009.07.035

Golden, J. P., Kim, J. S., Erickson, J. S., Hilliard, L. R., Howell, P. B., Anderson, G. P., … Ligler, F. S. (2009). Multi-wavelength microflow cytometer using groove-generated sheath flow. Lab on a Chip, 9(13), 1942. https://doi.org/10.1039/b822442k

Kim, J. S., Anderson, G. P., Erickson, J. S., Golden, J. P., Nasir, M., & Ligler, F. S. (2009). Multiplexed Detection of Bacteria and Toxins Using a Microflow Cytometer. Analytical Chemistry, 81(13), 5426–5432. https://doi.org/10.1021/ac9005827

Wojciechowski, J. R., Shriver-Lake, L. C., Yamaguchi, M. Y., Füreder Erwin, Pieler, R., Schamesberger, M., … Ligler, F. S. (2009). Organic Photodiodes for Biosensor Miniaturization. Analytical Chemistry, 81(9), 3455–3461. https://doi.org/10.1021/ac8027323

Ligler, F. S. (2009). Perspective on Optical Biosensors and Integrated Sensor Systems. Analytical Chemistry, 81(2), 519–526. https://doi.org/10.1021/ac8016289

Hu, J. E., Erickson, J. S., Taitt, C. R., Lin, B., Ligler, A. G., Blaney, K. M., … Ligler, F. S. (2008). A Parametric Study of Sample Lysis and DNA Purification Techniques for Use in Automated Devices. Analytical Letters, 41(10), 1701–1719. https://doi.org/10.1080/00032710802162186

Howell, P. B., Jr, Mott, D. R., Ligler, F. S., Golden, J. P., Kaplan, C. R., & Oran, E. S. (2008). A combinatorial approach to microfluidic mixing. Journal of Micromechanics and Microengineering, 18(11), 115019. https://doi.org/10.1088/0960-1317/18/11/115019

Erickson, J. S., & Ligler, F. S. (2008). Home diagnostics to music. Nature, 456(7219), 178–179. https://doi.org/10.1038/456178a

Johnson, B. J., Delehanty, J. B., Lin, B., & Ligler, F. S. (2008). Immobilized Proanthocyanidins for the Capture of Bacterial Lipopolysaccharides. Analytical Chemistry, 80(6), 2113–2117. https://doi.org/10.1021/ac7024128

Johnson, B. J., Lin, B., Dinderman, M. A., Rubin, R. A., Malanoski, A. P., & Ligler, F. S. (2008). Impact of cranberry on Escherichia coli cellular surface characteristics. Biochemical and Biophysical Research Communications, 377(3), 992–994. https://doi.org/10.1016/j.bbrc.2008.10.098

Ateya, D. A., Erickson, J. S., Howell, P. B., Jr, Hilliard, L. R., Golden, J. P., & Ligler, F. S. (2008). The good, the bad, and the tiny: a review of microflow cytometry. Analytical and Bioanalytical Chemistry, 391(5), 1485–1498. https://doi.org/10.1007/S00216-007-1827-5

Howell Jr, P. B., Golden, J. P., Hilliard, L. R., Erickson, J. S., Mott, D. R., & Ligler, F. S. (2008). Two simple and rugged designs for creating microfluidic sheath flow. Lab on a Chip, 8(7), 1097. https://doi.org/10.1039/b719381e

Kulagina, N., Shaffer, K., Ligler, F., & Taitt, C. (2007). Antimicrobial peptides as new recognition molecules for screening challenging species. Sensors and Actuators B: Chemical, 121(1), 150–157. https://doi.org/10.1016/j.snb.2006.09.044

Erickson, J. S., Hu, J. E., Anderson, G. P., Salls, A. C., Gray, S. A., Golden, J. P., … Ligler, F. S. (2007). Automated module for hybridization and staining of commercially produced nucleic acid microarrays. Microfluidics and Nanofluidics, 3(5), 623–628. https://doi.org/10.1007/S10404-007-0155-6

Delehanty, J. B., Johnson, B. J., Hickey, T. E., Pons, T., & Ligler, F. S. (2007). Binding and Neutralization of Lipopolysaccharides by Plant Proanthocyanidins. Journal of Natural Products, 70(11), 1718–1724. https://doi.org/10.1021/np0703601

Shriver‐Lake, L. C., Erickson, J. S., Sapsford, K. E., Ngundi, M. M., Shaffer, K. M., Kulagina, N. V., … Taitt, C. R. (2007). Blind Laboratory Trials for Multiple Pathogens in Spiked Food Matrices. Analytical Letters, 40(17), 3219–3231. https://doi.org/10.1080/00032710701672798

Johnson-White, B., Lin, B., & Ligler, F. S. (2007). Combination of Immunosensor Detection with Viability Testing and Confirmation Using the Polymerase Chain Reaction and Culture. Analytical Chemistry, 79(1), 140–146. https://doi.org/10.1021/ac061229l

Lassman, M. E., Rahbar, A., Medintz, I. L., & Ligler, F. S. (2007). Incorporation of18Oxygen into Peptide Mixtures and Analysis with Multi‐Dimensional Chromatography and Mass‐Spectroscopy. Analytical Letters, 40(10), 1864–1878. https://doi.org/10.1080/00032710701384659

O’Shaughnessy, T. J., Hu, J. E., Kulp, J. L., III, Daly, S. M., & Ligler, F. S. (2007). Laser ablation of micropores for formation of artificial planar lipid bilayers. Biomedical Microdevices, 9(6), 863–868. https://doi.org/10.1007/S10544-007-9099-6

Golden, J. P., Floyd-Smith, T. M., Mott, D. R., & Ligler, F. S. (2007). Target delivery in a microfluidic immunosensor. Biosensors and Bioelectronics, 22(11), 2763–2767. https://doi.org/10.1016/j.bios.2006.12.017

Sanchez-Carbayo, M., Shriver-Lake, L. C., Cordon-Cardo, C., & Ligler, F. S. (2006). 982: A Multianalyte Biosensor for Bladder Cancer Diagnostics. Journal of Urology, 175(4S), 316–317. https://doi.org/10.1016/S0022-5347(18)33207-5

Sapsford, K. E., Soto, C. M., Blum, A. S., Chatterji, A., Lin, T., Johnson, J. E., … Ratna, B. R. (2006). A cowpea mosaic virus nanoscaffold for multiplexed antibody conjugation: Application as an immunoassay tracer. Biosensors and Bioelectronics, 21(8), 1668–1673. https://doi.org/10.1016/j.bios.2005.09.003

Kulagina, N. V., Shaffer, K. M., Anderson, G. P., Ligler, F. S., & Taitt, C. R. (2006). Antimicrobial peptide-based array for Escherichia coli and Salmonella screening. Analytica Chimica Acta, 575(1), 9–15. https://doi.org/10.1016/j.aca.2006.05.082

Ngundi, M. M., Qadri, S. A., Wallace, E. V., Moore, M. H., Lassman, M. E., Shriver-Lake, L. C., … Taitt, C. R. (2006). Detection of Deoxynivalenol in Foods and Indoor Air Using an Array Biosensor. Environmental Science & Technology, 40(7), 2352–2356. https://doi.org/10.1021/es052396q

Ngundi, M. M., Taitt, C. R., McMurry, S. A., Kahne, D., & Ligler, F. S. (2006). Detection of bacterial toxins with monosaccharide arrays. Biosensors and Bioelectronics, 21(7), 1195–1201. https://doi.org/10.1016/j.bios.2005.05.001

Ligler, F. S., & Erickson, J. S. (2006). Diagnosis on disc. Nature, 440(7081), 159–160. https://doi.org/10.1038/440159a

Moreno-Bondi, M. C., Taitt, C. R., Shriver-Lake, L. C., & Ligler, F. S. (2006). Multiplexed measurement of serum antibodies using an array biosensor. Biosensors and Bioelectronics, 21(10), 1880–1886. https://doi.org/10.1016/j.bios.2005.12.018

Soper, S. A., Brown, K., Ellington, A., Frazier, B., Garcia-Manero, G., Gau, V., … Wilson, D. (2006). Point-of-care biosensor systems for cancer diagnostics/prognostics. Biosensors and Bioelectronics, 21(10), 1932–1942. https://doi.org/10.1016/j.bios.2006.01.006

Johnson-White, B., Buquo, L., Zeinali, M., & Ligler, F. S. (2006). Prevention of Nonspecific Bacterial Cell Adhesion in Immunoassays by Use of Cranberry Juice. Analytical Chemistry, 78(3), 853–857. https://doi.org/10.1021/ac051700v

Sapsford, K. E., Ngundi, M. M., Moore, M. H., Lassman, M. E., Shriver-Lake, L. C., Taitt, C. R., & Ligler, F. S. (2006). Rapid detection of foodborne contaminants using an Array Biosensor. Sensors and Actuators B: Chemical, 113(2), 599–607. https://doi.org/10.1016/j.snb.2005.07.008

Ngundi, M. M., Taitt, C. R., & Ligler, F. S. (2006). Simultaneous determination of kinetic parameters for the binding of cholera toxin to immobilized sialic acid and monoclonal antibody using an array biosensor. Biosensors and Bioelectronics, 22(1), 124–130. https://doi.org/10.1016/j.bios.2005.12.007

Kayagil, T. A., Richardson, J. A., Archer, M. J., Ligler, F. S., & Erickson, J. S. (2006). The beadwhacker for maintaining even dispersion of micron-sized beads. Measurement Science and Technology, 18(1), N1–N4. https://doi.org/10.1088/0957-0233/18/1/N01

Mott, D. R., Howell, Jr., P. B., Golden, J. P., Kaplan, C. R., Ligler, F. S., & Oran, E. S. (2006). Toolbox for the design of optimized microfluidic components. Lab on a Chip, 6(4), 540. https://doi.org/10.1039/b516459a

Howell, Jr., P. B., Mott, D. R., Fertig, S., Kaplan, C. R., Golden, J. P., Oran, E. S., & Ligler, F. S. (2005). A microfluidic mixer with grooves placed on the top and bottom of the channel. Lab on a Chip, 5(5), 524. https://doi.org/10.1039/b418243j

Golden, J., Taitt, C., Shriverlake, L., Shubin, Y., & Ligler, F. (2005). A portable automated multianalyte biosensor. Talanta, 65(5), 1078–1085. https://doi.org/10.1016/j.talanta.2004.03.072

Golden, J., Shriver-Lake, L., Sapsford, K., & Ligler, F. (2005). A “do-it-yourself” array biosensor. Methods, 37(1), 65–72. https://doi.org/10.1016/j.ymeth.2005.05.010

Kulagina, N. V., Lassman, M. E., Ligler, F. S., & Taitt, C. R. (2005). Antimicrobial Peptides for Detection of Bacteria in Biosensor Assays. Analytical Chemistry, 77(19), 6504–6508. https://doi.org/10.1021/ac050639r

Ngundi, M. M., Shriver-Lake, L. C., Moore, M. H., Lassman, M. E., Ligler, F. S., & Taitt, C. R. (2005). Array Biosensor for Detection of Ochratoxin A in Cereals and Beverages. Analytical Chemistry, 77(1), 148–154. https://doi.org/10.1021/ac048957y

Floyd-Smith, T. M., Golden, J. P., Howell, P. B., & Ligler, F. S. (2005). Characterization of passive microfluidic mixers fabricated using soft lithography. Microfluidics and Nanofluidics, 2(2), 180–183. https://doi.org/10.1007/S10404-005-0060-9

Taitt, C. R., Anderson, G. P., & Ligler, F. S. (2005). Evanescent wave fluorescence biosensors. Biosensors and Bioelectronics, 20(12), 2470–2487. https://doi.org/10.1016/j.bios.2004.10.026

Taitt, C. R., Golden, J. P., Shubin, Y. S., Shriver-Lake, L. C., Sapsford, K. E., Rasooly, A., & Ligler, F. S. (2004). A Portable Array Biosensor for Detecting Multiple Analytes in Complex Samples. Microbial Ecology, 47(2), 175–185. https://doi.org/10.1007/S00248-003-1011-1

Howell, Jr, P. B., Mott, D. R., Golden, J. P., & Ligler, F. S. (2004). Design and evaluation of a Dean vortex-based micromixer. Lab on a Chip, 4(6), 663. https://doi.org/10.1039/b407170k

Sapsford, K. E., Rasooly, A., Taitt, C. R., & Ligler, F. S. (2004). Detection ofCampylobacterandShigellaSpecies in Food Samples Using an Array Biosensor. Analytical Chemistry, 76(2), 433–440. https://doi.org/10.1021/ac035122z

Sapsford, K. E., Shubin, Y. S., Delehanty, J. B., Golden, J. P., Taitt, C. R., Shriver-Lake, L. C., & Ligler, F. S. (2004). Fluorescence-based array biosensors for detection of biohazards. Journal of Applied Microbiology, 96(1), 47–58. https://doi.org/10.1046/j.1365-2672.2003.02115.x

Sapsford, K. E., & Ligler, F. S. (2004). Real-time analysis of protein adsorption to a variety of thin films. Biosensors and Bioelectronics, 19(9), 1045–1055. https://doi.org/10.1016/j.bios.2003.10.002