Fan Zhang
https://orcid.org/0000-0001-6754-7500
Tissue Engineering, Biomaterial, Immunoengineering, Drug Delivery, Coronary Artery Bypass Graft, Tissue-engineered Vascular Graft, macrophage
Fan Zhang (she/her/hers) is a postdoc at UW in the Department of Bioengineering. Fan received a B.E. at Zhejiang Science and Technology University, China and a M.S. at North Carolina State University. She then received her Ph.D. degree in Fiber and Polymer Science in Dr. Martin King’s lab at North Carolina State University, engineering immunomodulatory biomaterials for tissue-engineered vascular graft. Fan’s current research focuses on understanding the mechanism underlying biomaterial-induced vascularization and the vascularization of engineered tissue and organ.
Works (11)
Updated: July 23rd, 2023 21:13
2023 article
A textile-reinforced composite vascular graft that modulates macrophage polarization and enhances endothelial cell migration, adhesion and proliferation in vitro
Zhang, F., Tao, H., Gluck, J. M., Wang, L., Daneshmand, M. A., & King, M. W. (2023, January 20). SOFT MATTER, Vol. 1.
MeSH headings : Endothelial Cells; Macrophage Activation; Textiles; Hydrogels; Cell Proliferation; Macrophages; Tissue Engineering
Sources: ORCID, Web Of Science
Added: February 9, 2023
2023 journal article
Effects of sterilization methods on gelatin methacryloyl hydrogel properties and macrophage gene expression in vitro
BIOMEDICAL MATERIALS, 18(1).
author keywords: gelatin methacryloyl; hydrogel; sterilization; macrophage phenotype; gene expression
MeSH headings : Hydrogels; Macrophages
Sources: ORCID, Web Of Science
Added: November 22, 2022
2023 journal article
Heparin Affinity-Based IL-4 Delivery to Modulate Macrophage Phenotype and Endothelial Cell Activity In Vitro
ACS APPLIED MATERIALS & INTERFACES, 15(23), 27457–27470.
author keywords: gelatin methacryloyl; heparin; interleukin4; hydrogel; macrophage; endothelial cell; immunomodulation
MeSH headings : Interleukin-4 / pharmacology; Heparin / pharmacology; Heparin / metabolism; Macrophages / metabolism; Phenotype; Hydrogels / pharmacology; Hydrogels / metabolism
Sources: Web Of Science, ORCID
Added: June 26, 2023
2022 article
A collagen/PLA hybrid scaffold supports tendon-derived cell growth for tendon repair and regeneration
Xie, Y., Zhang, F., Akkus, O., & King, M. W. (2022, July 2). JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, Vol. 7.
author keywords: biomaterials; biotextiles; collagen yarn; tendon regeneration; tissue engineering scaffold
MeSH headings : Cell Proliferation; Collagen; Humans; Polyesters; Regeneration; Rotator Cuff Injuries; Tendons; Tissue Engineering; Tissue Scaffolds
Sources: ORCID, Web Of Science
Added: July 3, 2022
2022 article
Immunomodulation Strategies for the Successful Regeneration of a Tissue-Engineered Vascular Graft
Zhang, F., & King, M. W. (2022, March 27). ADVANCED HEALTHCARE MATERIALS, Vol. 3.
author keywords: immune response; immunomodulation; macrophage; tissue engineering; tissue-engineered vascular grafts
MeSH headings : Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Humans; Immunity; Immunomodulation; Tissue Engineering
Sources: ORCID, Web Of Science
Added: March 31, 2022
2021 journal article
A hybrid vascular graft harnessing the superior mechanical properties of synthetic fibers and the biological performance of collagen filaments
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 118.
author keywords: Tissue-engineered vascular graft; Biomaterial; Hybrid; Electrochemically aligned collagen; Poly (lactic acid)
MeSH headings : Biocompatible Materials / pharmacology; Blood Vessel Prosthesis; Collagen; Endothelial Cells; Tissue Engineering; Tissue Scaffolds
Sources: Web Of Science, ORCID
Added: January 19, 2021
2020 journal article
Biodegradable Polymers as the Pivotal Player in the Design of Tissue Engineering Scaffolds
Advanced Healthcare Materials, 5, 1901358.
author keywords: biodegradable materials; biomaterials; composites; polymers; tissue engineering scaffolds
MeSH headings : Biocompatible Materials; Polymers; Regenerative Medicine; Tissue Engineering; Tissue Scaffolds
Source: ORCID
Added: May 19, 2020
2020 book
Coronary Artery Disease and The Evolution of Angioplasty Devices
In SpringerBriefs in Materials.
Source: ORCID
Added: May 27, 2020
2019 journal article
Application of Cognitive Task Performance Modeling for Assessing Usability of Transradial Prostheses
IEEE TRANSACTIONS ON HUMAN-MACHINE SYSTEMS, 49(4), 381–387.
author keywords: Cognitive modeling; GOMSL; mental workload; prosthetics
Sources: Web Of Science, ORCID
Added: August 12, 2019
2019 journal article
Engineering small-caliber vascular grafts from collagen filaments and nanofibers with comparable mechanical properties to native vessels
BIOFABRICATION, 11(3).
author keywords: small caliber vascular graft; endothelialization; knitting; electrospinning; electrochemically aligned collagen (ELAC) filament; collagen nanofibers; mechanical properties
MeSH headings : Animals; Biomechanical Phenomena; Blood Vessel Prosthesis; Blood Vessels / physiology; Cell Adhesion / drug effects; Cell Proliferation / drug effects; Collagen / pharmacology; Mice; Nanofibers / chemistry; Polyesters / chemistry; Rats; Sutures; Tissue Engineering / methods; Tissue Scaffolds / chemistry
Sources: ORCID, Web Of Science
Added: June 4, 2019
2019 chapter
Structural Design, Fabrication and Evaluation of Resorbable Fiber-Based Tissue Engineering Scaffolds
In & L. Q. Z. (E. In E. Jacob-Lopes (Ed.), Biotechnology and Bioengineering.
Ed(s): &. In E. Jacob-Lopes
www.intechopen.com (publisher PDF)
Source: ORCID
Added: February 16, 2020
Employment
Updated: November 10th, 2022 15:30
2022 - present
University of Washington Seattle, Washington, US
Postdoctoral Scholar
Bioengineering
2018 - present
North Carolina State University Raleigh, NC, US
Research Assistant
Wilson College of Textiles
2018 - 2021
North Carolina State University Raleigh, NC, US
Teaching Assistant
UNC/NCSU Joint Department of Biomedical Engineering
2021 - 2021
North Carolina State University Analytical Instrumentation Facility Raleigh, North Carolina, US
Laboratory assistant
Bio Sample Preparation Lab
2019 - 2019
Novozymes Franklinton, North Carolina, US
R&D Intern
Research and Development
Education
Updated: July 31st, 2022 00:14
2018 - 2022
North Carolina State University Raleigh, North Carolina, US
PhD
Wilson College of Textiles, Fiber and Polymer Science
Funding History
Funding history based on the linked ORCID record. Updated: July 4th, 2021 17:44
grant
January 1 - December 1, 2021
Textile-Reinforced Composite Vascular Graft for Cardiac Patients
AATCC Foundation
award
December 1, 2020
A Spatiotemporally Controlled Multi-Factor Releasing Composite Scaffold for Vascular Tissue Engineering
Society for Biomaterials
grant
March 1 - December 1, 2020
WBC 2020 - 11th World Biomaterials Congress
Ellen Rohde Women’s Leadership Initiative
grant
January 1 - December 1, 2020
A hybrid vascular graft harnessing the superior mechanical properties of synthetic fibers and the bioactivity of collagen yarns
AATCC Foundation
