Fan Zhang

Tissue Engineering, Biomaterial, Immunoengineering, Drug Delivery, Coronary Artery Bypass Graft, Tissue-engineered Vascular Graft, macrophage

Fan Zhang (she/her/hers) is a postdoc at UW in the Department of Bioengineering. Fan received a B.E. at Zhejiang Science and Technology University, China and a M.S. at North Carolina State University. She then received her Ph.D. degree in Fiber and Polymer Science in Dr. Martin King’s lab at North Carolina State University, engineering immunomodulatory biomaterials for tissue-engineered vascular graft. Fan’s current research focuses on understanding the mechanism underlying biomaterial-induced vascularization and the vascularization of engineered tissue and organ.

Works (11)

Updated: July 23rd, 2023 21:13

2023 article

A textile-reinforced composite vascular graft that modulates macrophage polarization and enhances endothelial cell migration, adhesion and proliferation in vitro

Zhang, F., Tao, H., Gluck, J. M., Wang, L., Daneshmand, M. A., & King, M. W. (2023, January 20). SOFT MATTER, Vol. 1.

By: F. Zhang n, H. Tao*, J. Gluck n, L. Wang*, M. Daneshmand & M. King n

MeSH headings : Endothelial Cells; Macrophage Activation; Textiles; Hydrogels; Cell Proliferation; Macrophages; Tissue Engineering
Sources: ORCID, Web Of Science
Added: February 9, 2023

2023 journal article

Effects of sterilization methods on gelatin methacryloyl hydrogel properties and macrophage gene expression in vitro


By: F. Zhang*, G. Scull*, J. Gluck*, A. Brown* & M. King*

author keywords: gelatin methacryloyl; hydrogel; sterilization; macrophage phenotype; gene expression
MeSH headings : Hydrogels; Macrophages
Sources: ORCID, Web Of Science
Added: November 22, 2022

2023 journal article

Heparin Affinity-Based IL-4 Delivery to Modulate Macrophage Phenotype and Endothelial Cell Activity In Vitro


By: F. Zhang n, J. Gluck n, A. Brown n, D. Zaharoff n & M. King n

author keywords: gelatin methacryloyl; heparin; interleukin4; hydrogel; macrophage; endothelial cell; immunomodulation
MeSH headings : Interleukin-4 / pharmacology; Heparin / pharmacology; Heparin / metabolism; Macrophages / metabolism; Phenotype; Hydrogels / pharmacology; Hydrogels / metabolism
Sources: Web Of Science, ORCID
Added: June 26, 2023

2022 article

A collagen/PLA hybrid scaffold supports tendon-derived cell growth for tendon repair and regeneration


By: Y. Xie n, F. Zhang n, O. Akkus* & M. King n

author keywords: biomaterials; biotextiles; collagen yarn; tendon regeneration; tissue engineering scaffold
MeSH headings : Cell Proliferation; Collagen; Humans; Polyesters; Regeneration; Rotator Cuff Injuries; Tendons; Tissue Engineering; Tissue Scaffolds
Sources: ORCID, Web Of Science
Added: July 3, 2022

2022 article

Immunomodulation Strategies for the Successful Regeneration of a Tissue-Engineered Vascular Graft

Zhang, F., & King, M. W. (2022, March 27). ADVANCED HEALTHCARE MATERIALS, Vol. 3.

By: F. Zhang n & M. King n

author keywords: immune response; immunomodulation; macrophage; tissue engineering; tissue-engineered vascular grafts
MeSH headings : Blood Vessel Prosthesis; Blood Vessel Prosthesis Implantation; Humans; Immunity; Immunomodulation; Tissue Engineering
Sources: ORCID, Web Of Science
Added: March 31, 2022

2021 journal article

A hybrid vascular graft harnessing the superior mechanical properties of synthetic fibers and the biological performance of collagen filaments


author keywords: Tissue-engineered vascular graft; Biomaterial; Hybrid; Electrochemically aligned collagen; Poly (lactic acid)
MeSH headings : Biocompatible Materials / pharmacology; Blood Vessel Prosthesis; Collagen; Endothelial Cells; Tissue Engineering; Tissue Scaffolds
Sources: Web Of Science, ORCID
Added: January 19, 2021

2020 journal article

Biodegradable Polymers as the Pivotal Player in the Design of Tissue Engineering Scaffolds

Advanced Healthcare Materials, 5, 1901358.

By: F. Zhang n & M. King n

author keywords: biodegradable materials; biomaterials; composites; polymers; tissue engineering scaffolds
MeSH headings : Biocompatible Materials; Polymers; Regenerative Medicine; Tissue Engineering; Tissue Scaffolds
Source: ORCID
Added: May 19, 2020

2020 book

Coronary Artery Disease and The Evolution of Angioplasty Devices

In SpringerBriefs in Materials.

Source: ORCID
Added: May 27, 2020

2019 journal article

Application of Cognitive Task Performance Modeling for Assessing Usability of Transradial Prostheses


By: M. Zahabi*, M. White*, W. Zhang n, A. Winslow n, F. Zhang n, H. Huang n, D. Kaber*

author keywords: Cognitive modeling; GOMSL; mental workload; prosthetics
Sources: Web Of Science, ORCID
Added: August 12, 2019

2019 journal article

Engineering small-caliber vascular grafts from collagen filaments and nanofibers with comparable mechanical properties to native vessels


By: F. Zhang n, Y. Xie n, H. Celik*, O. Akkus*, S. Bernacki* & M. King n

author keywords: small caliber vascular graft; endothelialization; knitting; electrospinning; electrochemically aligned collagen (ELAC) filament; collagen nanofibers; mechanical properties
MeSH headings : Animals; Biomechanical Phenomena; Blood Vessel Prosthesis; Blood Vessels / physiology; Cell Adhesion / drug effects; Cell Proliferation / drug effects; Collagen / pharmacology; Mice; Nanofibers / chemistry; Polyesters / chemistry; Rats; Sutures; Tissue Engineering / methods; Tissue Scaffolds / chemistry
Sources: ORCID, Web Of Science
Added: June 4, 2019

2019 chapter

Structural Design, Fabrication and Evaluation of Resorbable Fiber-Based Tissue Engineering Scaffolds

In & L. Q. Z. (E. In E. Jacob-Lopes (Ed.), Biotechnology and Bioengineering.

By: M. King, J. Chen, M. Deshpande*, T. He, H. Ramakrishna, Y. Xie, F. Zhang*, F. Zhao

Ed(s): &. In E. Jacob-Lopes

Source: ORCID
Added: February 16, 2020


Updated: November 10th, 2022 15:30

2022 - present

University of Washington Seattle, Washington, US
Postdoctoral Scholar Bioengineering

2018 - present

North Carolina State University Raleigh, NC, US
Research Assistant Wilson College of Textiles

2018 - 2021

North Carolina State University Raleigh, NC, US
Teaching Assistant UNC/NCSU Joint Department of Biomedical Engineering

2021 - 2021

North Carolina State University Analytical Instrumentation Facility Raleigh, North Carolina, US
Laboratory assistant Bio Sample Preparation Lab

2019 - 2019

Novozymes Franklinton, North Carolina, US
R&D Intern Research and Development


Updated: July 31st, 2022 00:14

2018 - 2022

North Carolina State University Raleigh, North Carolina, US
PhD Wilson College of Textiles, Fiber and Polymer Science

Funding History

Funding history based on the linked ORCID record. Updated: July 4th, 2021 17:44

grant January 1 - December 1, 2021
Textile-Reinforced Composite Vascular Graft for Cardiac Patients
AATCC Foundation
award December 1, 2020
A Spatiotemporally Controlled Multi-Factor Releasing Composite Scaffold for Vascular Tissue Engineering
Society for Biomaterials
grant March 1 - December 1, 2020
WBC 2020 - 11th World Biomaterials Congress
Ellen Rohde Women’s Leadership Initiative
grant January 1 - December 1, 2020
A hybrid vascular graft harnessing the superior mechanical properties of synthetic fibers and the bioactivity of collagen yarns
AATCC Foundation