Guojun Chen
Works (16)
Updated: July 5th, 2023 15:34
2022 journal article
Scattered seeding of CAR T cells in solid tumors augments anticancer efficacy
NATIONAL SCIENCE REVIEW, 9(3).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: drug delivery; CAR T therapy; microneedle patch; solid tumor treatment; cell delivery
academic.oup.com (publisher PDF)
Source: Web Of Science
Added: March 28, 2022
2021 article
Bioorthogonal catalytic patch
Chen, Z., Li, H., Bian, Y., Wang, Z., Chen, G., Zhang, X., … Gu, Z. (2021, May 10). NATURE NANOTECHNOLOGY.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacokinetics; Antineoplastic Agents / pharmacology; Catalysis; Drug Delivery Systems; Hep G2 Cells; Humans; Melanoma, Experimental; Metal Nanoparticles / chemistry; Metal Nanoparticles / therapeutic use; Mice; Palladium / chemistry; Palladium / pharmacokinetics; Palladium / pharmacology; Prodrugs / chemistry; Prodrugs / pharmacokinetics; Prodrugs / pharmacology; Titanium / chemistry; Titanium / pharmacokinetics; Titanium / pharmacology
Source: Web Of Science
Added: June 10, 2021
2020 journal article
Glucose-responsive insulin patch for the regulation of blood glucose in mice and minipigs
NATURE BIOMEDICAL ENGINEERING, 4(5), 499–506.
co-author countries:
United States of America 🇺🇸
MeSH headings : Animals; Blood Glucose / metabolism; Diabetes Mellitus, Experimental / blood; Disease Models, Animal; Drug Delivery Systems; Humans; Insulin / pharmacology; Insulin Secretion / drug effects; Male; Mice, Inbred C57BL; Needles; Swine; Swine, Miniature; Transdermal Patch
Source: Web Of Science
Added: February 17, 2020
2019 journal article
A Dual-Bioresponsive Drug-Delivery Depot for Combination of Epigenetic Modulation and Immune Checkpoint Blockade
ADVANCED MATERIALS, 31(17).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: bioresponsive materials; drug delivery; epigenetic modulation; immune checkpoint blockade; immunotherapy
MeSH headings : Animals; Antibodies, Monoclonal / pharmacology; Antibodies, Monoclonal, Humanized; Antineoplastic Agents / chemical synthesis; Antineoplastic Agents / pharmacology; Calcium Carbonate / chemistry; Cell Line, Tumor; Cytidine / analogs & derivatives; Cytidine / pharmacology; Drug Delivery Systems / methods; Drug Liberation; Drug Therapy, Combination / methods; Humans; Hydrogen-Ion Concentration; Immunosuppressive Agents / chemistry; Immunosuppressive Agents / pharmacology; Immunotherapy / methods; Melanoma / drug therapy; Nanoparticles / chemistry; Programmed Cell Death 1 Receptor / metabolism; Reactive Oxygen Species / metabolism; Tumor Microenvironment / drug effects
Source: Web Of Science
Added: May 13, 2019
2019 journal article
A Therapeutic Microneedle Patch Made from Hair-Derived Keratin for Promoting Hair Regrowth
ACS NANO, 13(4), 4354–4360.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: drug delivery; microneedle; exosome; keratin; hair regrowth; transdermal drug delivery
MeSH headings : Animals; Cell Line; Delayed-Action Preparations / chemistry; Drug Delivery Systems / instrumentation; Equipment Design; Hair / chemistry; Hair / drug effects; Hair / growth & development; Hair Follicle / drug effects; Hair Follicle / growth & development; Humans; Injections, Subcutaneous; Keratins / chemistry; Mice, Inbred C57BL; Transdermal Patch
Source: Web Of Science
Added: June 4, 2019
2019 journal article
Adipocytes as Anticancer Drug Delivery Depot
MATTER, 1(5), 1203–1214.
co-author countries:
United States of America 🇺🇸
Source: Web Of Science
Added: April 6, 2020
2019 journal article
Bioresponsive Protein Complex of aPD1 and aCD47 Antibodies for Enhanced Immunotherapy
NANO LETTERS, 19(8), 4879–4889.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: Drug delivery; immunotherapy; immune checkpoint blockade; bioresponsive; nanomedicine
MeSH headings : Animals; Antibodies, Monoclonal / immunology; Antibodies, Monoclonal / therapeutic use; Antineoplastic Agents, Immunological / immunology; Antineoplastic Agents, Immunological / therapeutic use; CD47 Antigen / immunology; Female; Immunotherapy; Melanoma / immunology; Melanoma / therapy; Mice, Inbred C57BL; Programmed Cell Death 1 Receptor / immunology; Reactive Oxygen Species / immunology; Tumor Microenvironment / drug effects
Source: Web Of Science
Added: September 3, 2019
2019 journal article
Charge-switchable polymeric complex for glucose-responsive insulin delivery in mice and pigs
SCIENCE ADVANCES, 5(7).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Blood Glucose / drug effects; Diabetes Mellitus, Experimental / drug therapy; Drug Carriers / chemical synthesis; Drug Carriers / chemistry; Drug Delivery Systems; Insulin / administration & dosage; Mice; Molecular Structure; Polymers / chemical synthesis; Polymers / chemistry; Swine
Source: Web Of Science
Added: August 19, 2019
2019 journal article
Enhanced local cancer therapy using a CA4P and CDDP co-loaded polypeptide gel depot
BIOMATERIALS SCIENCE, 7(3), 860–866.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Cell Line, Tumor; Cell Survival / drug effects; Cisplatin / chemistry; Cisplatin / metabolism; Cisplatin / therapeutic use; Cisplatin / toxicity; Colonic Neoplasms / drug therapy; Colonic Neoplasms / pathology; Drug Liberation; Female; Humans; Hydrogels / chemical synthesis; Hydrogels / chemistry; Mice, Inbred BALB C; Peptides / chemistry; Polymers / chemical synthesis; Polymers / chemistry; Stilbenes / chemistry; Stilbenes / metabolism; Stilbenes / therapeutic use; Stilbenes / toxicity; Transplantation, Heterologous; Tumor Microenvironment / drug effects
Source: Web Of Science
Added: April 22, 2019
2019 journal article
Extraction of Plant DNA by Microneedle Patch for Rapid Detection of Plant Diseases
ACS Nano, 13(6), 6540–6549.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: plant disease; DNA extraction; microneedle patch; Phytophthora infestans; nucleic acid amplification; point-of-care diagnostics
MeSH headings : DNA Barcoding, Taxonomic / instrumentation; DNA Barcoding, Taxonomic / methods; DNA, Fungal / chemistry; DNA, Fungal / genetics; Solanum lycopersicum / microbiology; Metagenomics / instrumentation; Metagenomics / methods; Needles; Phytophthora / genetics; Phytophthora / pathogenicity; Plant Diseases / microbiology; Plant Leaves / chemistry; Plant Leaves / microbiology
Sources: Web Of Science, ORCID, Crossref
Added: July 15, 2019
2019 journal article
In situ sprayed bioresponsive immunotherapeutic gel for post-surgical cancer treatment
NATURE NANOTECHNOLOGY, 14(1), 89-+.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Biocompatible Materials / chemistry; Calcium Carbonate / chemistry; Female; Fibrin / chemistry; Gels / chemistry; Humans; Immunity; Immunotherapy / methods; Luminescent Measurements; Melanoma, Experimental / pathology; Mice, Inbred C57BL; Nanoparticles / chemistry; Nanoparticles / ultrastructure; Neoplasm Recurrence, Local / pathology; Neoplasms / pathology; Neoplasms / surgery; Phagocytosis
Source: Web Of Science
Added: January 21, 2019
2019 journal article
Photothermal Therapy Promotes Tumor Infiltration and Antitumor Activity of CAR T Cells
ADVANCED MATERIALS, 31(23).
co-author countries:
China 🇨🇳 United States of America 🇺🇸
author keywords: CAR T cells; cell therapy; drug delivery; immunotherapy; photothermal therapy
MeSH headings : Animals; Antigens / metabolism; Cell Line, Tumor; Chondroitin Sulfate Proteoglycans / metabolism; Combined Modality Therapy; Female; Heterografts; Humans; Hyperthermia, Induced; Immunotherapy, Adoptive / methods; Indocyanine Green / chemistry; Melanoma / pathology; Melanoma / therapy; Membrane Proteins / metabolism; Mice, SCID; Nanoparticles / chemistry; Photosensitizing Agents / chemistry; Phototherapy / methods; Polylactic Acid-Polyglycolic Acid Copolymer / chemistry; Proteoglycans / metabolism; Skin Neoplasms / pathology; Skin Neoplasms / therapy; T-Lymphocytes / metabolism; T-Lymphocytes / transplantation; Tumor Microenvironment
Source: Web Of Science
Added: July 22, 2019
2018 review
Advances in glycosylation-mediated cancer-targeted drug delivery
[Review of ]. DRUG DISCOVERY TODAY, 23(5), 1126–1138.
co-author countries:
China 🇨🇳 United States of America 🇺🇸
MeSH headings : Animals; Drug Delivery Systems; Glycosylation; Humans; Neoplasms / drug therapy
Source: Web Of Science
Added: August 6, 2018
2018 review
Advances in liquid metals for biomedical applications
[Review of ]. CHEMICAL SOCIETY REVIEWS, 47(8), 2518–2533.
co-author countries:
Germany 🇩🇪 Poland 🇵🇱 United States of America 🇺🇸
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Biocompatible Materials / chemistry; Biocompatible Materials / toxicity; Biosensing Techniques / methods; Drug Carriers / chemistry; Drug Carriers / toxicity; Gallium / chemistry; Humans; Metals / chemistry; Microfluidics / instrumentation; Microfluidics / methods; Nanostructures / chemistry; Neoplasms / diagnosis; Neoplasms / drug therapy; Photosensitizing Agents / chemistry; Photosensitizing Agents / therapeutic use
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Delivery Strategies for Immune Checkpoint Blockade
ADVANCED HEALTHCARE MATERIALS, 7(20).
co-author countries:
United States of America 🇺🇸
author keywords: biomaterials; cancer therapy; drug delivery; immune checkpoint blockade; immunotherapy
MeSH headings : Autoimmune Diseases / immunology; Autoimmune Diseases / therapy; Humans; Immunotherapy / methods; Neoplasms / immunology; Neoplasms / therapy
Source: Web Of Science
Added: November 19, 2018
2018 article
The potential of a microneedle patch for reducing obesity
EXPERT OPINION ON DRUG DELIVERY, Vol. 15, pp. 431–433.
co-author countries:
United States of America 🇺🇸
author keywords: Obesity; browning; microneedle; intradermal delivery
Source: Web Of Science
Added: August 6, 2018
