Works (7)
Updated: March 29th, 2024 11:03
2023 journal article
Gestational exposure to FireMaster® 550 (FM 550) disrupts the placenta-brain axis in a socially monogamous rodent species, the prairie vole (<i>Microtus ochrogaster</i>)
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 576.
author keywords: Pregnancy; EDCs; Endocrine disruptors; Neurotoxicology; Developmental toxicology; Organophosphate
TL;DR:
Prairie voles are used, a monogamous and bi-parental rodent, leveraged for decades to decipher the underpinnings of social behaviors, to examine the impact of fetal FR exposure on gene targets in the mid-gestational placenta and fetal brain and provide insights on the mechanisms by which FRs impair neurodevelopment and later in life social behaviors.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: October 16, 2023
2023 journal article
Maternal organophosphate flame retardant exposure alters the developing mesencephalic dopamine system in fetal rat
TOXICOLOGICAL SCIENCES, 191(2), 357–373.
author keywords: neurodevelopment; monoamine; OPFR; OPE; flame retardants; neurotransmitters; neurotoxicity; neurotoxicology; prenatal; reproductive and developmental toxicology; mesocortical dopamine system; tissue clearing light sheet microscopy.
TL;DR:
Results indicate maternal exposure to OPFRs alters the development trajectory of the embryonic dopaminergic system and adds to growing evidence of OPFR developmental neurotoxicity.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
Sources: Web Of Science, NC State University Libraries
Added: February 12, 2024
2022 article
Impacts of Gestational FireMaster 550 (FM 550) Exposure on the Neonatal Cortex are Sex Specific and Largely Attributable to the Organophosphate Esters
Witchey, S. K., Doyle, M. G., Fredenburg, J. D., St Armour, G., Horman, B., Odenkirk, M. T., … Patisaul, H. B. (2022, September 8). NEUROENDOCRINOLOGY, Vol. 9.
TL;DR:
This study reveals multiple mechanisms by which the components of a common FR mixture are developmentally neurotoxic and that the OPFRs may be the compounds of greatest concern.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: September 26, 2022
2020 journal article
Effects of Prenatal Exposure to a Mixture of Organophosphhate Flame Ritardants on Placental Gene Expression and Serotonergic Innervaion in the Fetal Rat Brain
TOXICOLOGICAL SCIENCES, 176(1), 203–223.
author keywords: endocrine disruptors; endocrine toxicology; flame retardants; metabolome; neurotoxicity; developmental; neurotoxicology; neurotransmitter; developmental toxicity; prenatal; reproductive and developmental toxicology; developmental/teratology
MeSH headings : Animals; Brain / drug effects; Female; Fetal Development; Fetus; Flame Retardants / toxicity; Gene Expression; Humans; Male; Organophosphates; Organophosphorus Compounds; Placenta / metabolism; Plasticizers; Polybrominated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Serotonin / metabolism
TL;DR:
Findings suggest that OPFRs have the potential to impact the 5-HTergic system in the fetal forebrain by disrupting placental Trp metabolism.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 14, 2020
2020 journal article
Gene expression networks in the Drosophila Genetic Reference Panel
GENOME RESEARCH, 30(3), 485–496.
MeSH headings : Animals; DNA Transposable Elements; Drosophila melanogaster / genetics; Drosophila melanogaster / metabolism; Drosophila melanogaster / microbiology; Female; Gene Expression Regulation; Gene Regulatory Networks; Genetic Variation; High-Throughput Nucleotide Sequencing; Male; Microbiota / genetics; Quantitative Trait Loci; Sequence Analysis, RNA
TL;DR:
This study performed deep RNA sequencing of 200 Drosophila Genetic Reference Panel inbred lines with complete genome sequences and mapped expression quantitative trait loci for annotated genes, novel transcribed regions, transposable elements and microbial species, providing new insights regarding the role of natural genetic variation in regulating gene expression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 14, 2020
journal article
Genetic and genomic response to selection for food consumption in Drosophila melanogaster
Garlapow, M. E., Everett, L. J., Zhou, S. S., Gearhart, A. W., Fay, K. A., Huang, W., … Mackay, T. F. C. Behavior Genetics, 47(2), 227–243.
Source: NC State University Libraries
Added: August 6, 2018
journal article
Obp56h modulates mating behavior in Drosophila melanogaster
Shorter, J. R., Dembeck, L. M., Everett, L. J., Morozova, T. V., Arya, G. H., Turlapati, L., … Anholt, R. R. H. G3-Genes Genomes Genetics, 6(10), 3335–3342.
Source: NC State University Libraries
Added: August 6, 2018
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