@inproceedings{medwig_choi_castillo_yu_2024, title={Practical quantum approximate optimization algorithms on IBM quantum processors}, volume={11391}, DOI={10.1117/12.3002940}, abstractNote={In recent years, significant progress has been made in building quantum computers by several companies. Despite the progress, these noisy intermediate-scale quantum (NISQ) computers still suffer from several noises and errors such as measurement errors, multi-qubit gate errors, and worse, short decoherence times. Though quantum computer vendors are releasing better quantum computers in terms of Quantum Volume, the quantum device still remains far from quantum supremacy in practical problems. The Quantum Approximate Optimization Algorithm (QAOA) was suggested to potentially demonstrate a computational advantage in combinatorial optimization problems on NISQ computers. In this paper, we optimize the QAOA circuits and to scale the problem size on IBM quantum processors. In addition, we study the effect of the length of the QAOA ansatz on IBM quantum processors and discuss optimal implementation methods for scalable QAOA. We test our implementations on the MaxCut problems.}, booktitle={Quantum Computing, Communication, and Simulation IV}, publisher={SPIE}, author={Medwig, Gregory and Choi, Sua and Castillo, Paulo C. and Yu, Kwangmin}, editor={Hemmer, Philip R. and Migdall, Alan L.Editors}, year={2024}, month={Mar}, pages={53} }
 @article{farella_medwig_abrahao_nomerotski_2024, title={Spectral characterization of an SPDC source with a fast broadband spectrometer}, url={https://doi.org/10.1063/5.0168423}, DOI={10.1063/5.0168423}, abstractNote={Knowing the properties of single photons produced in a Spontaneous Parametric Down-Conversion (SPDC) source can be crucial for specific applications and uses. In particular, the spectral properties are of key relevance. Here, we investigate a commercial SPDC source using our fast broadband spectrometer. Our analysis is a valid method for other SPDC sources, as well as other single-photon generation techniques, thus providing a good example of how to use this spectrometer design. We calibrate the spectrometer using known lines of the argon emission spectrum. We show that the two down-converted photons from the SPDC source have different spectral properties depending on the pump power, and under which condition we measured spectrally similar down-converted photons. Finally, we were able to reconstruct and investigate the spectral information for the pump photon.}, journal={AIP Advances}, author={Farella, Brianna and Medwig, Gregory and Abrahao, Raphael A. and Nomerotski, Andrei}, year={2024}, month={Apr} }
 @article{richardson_barahona_medwig_johns_pérez_sode_daniele_miller_lobaton_pavlidis_2024, title={Towards monitoring of critical illness via the detection of histones with extended gate field-effect transistor sensors}, volume={19}, DOI={10.1016/j.biosx.2024.100501}, abstractNote={Extracellular histone proteins in the blood indicate a heightened risk of morbidity after trauma or in major illnesses such as sepsis. We present the development of an aptasensor for histone detection with an extended gate field-effect transistor (EGFET) configuration, which benefits from low power consumption, rapid response, and compatibility with miniaturized gold electrodes. Histones have a high isoelectric point and charge density, which cause them to physically adsorb to non-specific elements of the sensor that have available electrostatic charges. To combat this, the sensing surface is formed with a thiol-modified, high-affinity and histone-specific RNA aptamer sequence and by co-immobilizing with poly(ethylene glycol) methyl ether thiol (PEG) as a blocking agent. Surface plasmon resonance (SPR) is used to analyze aptamer and PEG immobilization strategies, confirm histone binding, and calculate kinetic binding constants. Through comparison of different blocking agents and time-dependent preparation, the ideal equilibrium dissociation constant (KD) is estimated to be below 200 pM, which is the upper range of extracellular histone concentrations in critically ill patients with high mortality. The EGFET sensitivity of the optimized aptasensor is 6.65 mV/decade concentration change for histone H4 with a physiologically relevant 5 pM limit of detection. Selectivity tests with 100 nM bovine serum albumin (BSA) demonstrate a signal response that is 13-fold smaller than for histones. This EGFET aptasensor platform is suitable for future point-of-care monitoring of histone levels in critically ill patients, thus permitting the early detection of increased risk and the need for more aggressive interventional measures to prevent mortality.}, journal={Biosensors and Bioelectronics: X}, publisher={Elsevier BV}, author={Richardson, Hayley and Barahona, Jeffrey and Medwig, Greg and Johns, Angela and Pérez, Lina M. Acosta and Sode, Koji and Daniele, Michael and Miller, Francis J. and Lobaton, Edgar and Pavlidis, Spyridon}, year={2024}, month={Aug}, pages={100501} }
 @article{pavlidis_medwig_thomas_2024, title={Ultrawide-Bandgap Semiconductors for High-Frequency Devices}, volume={25}, ISSN={["1557-9581"]}, url={https://doi.org/10.1109/MMM.2024.3428193}, DOI={10.1109/MMM.2024.3428193}, number={10}, journal={IEEE MICROWAVE MAGAZINE}, author={Pavlidis, Spyridon and Medwig, Greg and Thomas, Michael}, year={2024}, month={Oct}, pages={68–79} }
 @inproceedings{conley_choi_medwig_mroczko_wan_castillo_yu_2023, title={Quantum optimization algorithm for solving elliptic boundary value problems on D-Wave quantum annealing device}, volume={11391}, DOI={10.1117/12.2649076}, abstractNote={The quantum annealing devices, which encode the solution to a computational problem in the ground state of a quantum Hamiltonian, are implemented in D-Wave systems with more than 2,000 qubits. However, quantum annealing can solve only a classical combinatorial optimization problem such as an Ising model, or equivalently, a quadratic unconstrained binary optimization (QUBO) problem. In this paper, we formulate the QUBO model to solve elliptic problems with Dirichlet and Neumann boundary conditions using the finite element method. In this formulation, we develop the objective function of quadratic binary variables represented by qubits and the system finds the binary string combination minimizing the objective function globally. Based on the QUBO formulation, we introduce an iterative algorithm to solve the elliptic problems. We discuss the validation of the modeling on the D-Wave quantum annealing system.}, booktitle={Quantum Computing, Communication, and Simulation III}, publisher={SPIE}, author={Conley, Rebecca and Choi, Deokkyu and Medwig, Gregory and Mroczko, Eric and Wan, David and Castillo, Paulo C. and Yu, Kwangmin}, editor={Hemmer, Philip R. and Migdall, Alan L.Editors}, year={2023}, month={Mar}, pages={29} }
 @inproceedings{cordova_medwig_roy_karmakar_2021, title={Artificial intelligence (AI) to study self-discharge batteries}, volume={28}, DOI={10.1109/uemcon53757.2021.9666507}, abstractNote={This work shows the application of artificial intelligence (AI) in the selection of proper batteries for various applications. A graphical user interface (GUI) to estimate the status or the life of a battery based on its type and capacity is developed. The GUI interface is used in the front end for user input and output and different self-discharge equations are solved in the back end to produce different results and plots. A program that calculates the self-discharge of different chemical reactions in a battery for every day, can have several advantages to the companies and to the stores. It is time saving and easy to use for most engineers and people outside the major. So far, the program has multiple tabs for different kinds of uses in the battery’s self-discharge. This work also provides options to categorize various batteries for various applications.}, booktitle={2021 IEEE 12th Annual Ubiquitous Computing, Electronics & Mobile Communication Conference (UEMCON)}, publisher={IEEE}, author={Cordova, Diego and Medwig, Gregory and Roy, Abhijith Variathu and Karmakar, Supriya}, year={2021}, month={Dec}, pages={0298–0302} }