Works (5)
Updated: May 23rd, 2024 05:00
2024 journal article
Data-dependent and -independent acquisition lipidomics analysis reveals the tissue-dependent effect of metformin on lipid metabolism
METABOLOMICS, 20(3).
author keywords: Metformin; Intestinal metabolism; Lipidomics; DIA
open access via doi.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: May 20, 2024
2024 journal article
Myeloid cell MHC I expression drives CD8<SUP>+</SUP> T cell activation in nonalcoholic steatohepatitis
FRONTIERS IN IMMUNOLOGY, 14.
Contributors: T. Williams n , V. Adams n, L. Collins n , J. Holmes n, P. Hess n , H. Atkins n, n, X. Liu n
Ed(s): T. Williams n , L. Collins n & A. Kennedy n
author keywords: liver; NASH; fibrosis; H2Kb; CD8(+) T cells; immunopeptidome
TL;DR:
Activated hepatic CD8+ T cells are dependent on myeloid cell MHC class I expression in diet induced NASH to promote inflammation and fibrosis and a role of NADPH oxidase in the production of Ncf2 peptide generation is suggested.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 28, 2024
2023 journal article
Histone malonylation is regulated by SIRT5 and KAT2A
ISCIENCE, 26(3).
TL;DR:
The role of histone malonylation in ribosomal gene expression is highlighted by mass spectrometry and it is reported that availability of malonyl-co-enzyme A (malonyL-CoA), an endogenous provider ofmalonyl groups, affects lysinemalonylation, and that the deacylase SIRT5 selectively reduces malonylated of histones.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: June 12, 2023
2022 journal article
C-13 tracer analysis suggests extensive recycling of endogenous CO2 in vivo
CANCER & METABOLISM, 10(1).
author keywords: C-13 tracing; High-resolution mass spectrometry; Anaplerotic metabolism; CO2 recycling
TL;DR:
The results show that recycling of endogenous CO2 is substantial in vivo and incorporation of endogenous 13CO2 into M’+ 1 metabolites is substantial and should be considered, and provide a new paradigm to understand carbon atom transformations in vivo.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 18, 2022
2022 journal article
Prioritize biologically relevant ions for data-independent acquisition (BRI-DIA) in LC-MS/MS-based lipidomics analysis
METABOLOMICS, 18(8).
MeSH headings : Animals; Cardiolipins; Chromatography, Liquid / methods; Ions; Lipidomics; Metabolomics; Mice; Reproducibility of Results; Tandem Mass Spectrometry / methods
TL;DR:
A novel workflow using biologically relevant lipids to construct inclusion list for data-independent acquisition (DIA), named as BRI-DIA workflow, which is as efficient as traditional DDA method in profiling lipids, but offers better consistency of lipid identification, compared to D DA method.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: July 26, 2022
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