Works (4)
Updated: April 4th, 2024 13:59
2023 article
Mini-Review: Enteric glia of the tumor microenvironment: An affair of corruption
Mariant, C. L., Bacola, G., & Van Landeghem, L. (2023, September 25). NEUROSCIENCE LETTERS, Vol. 814.
author keywords: Enteric glial cell; Colon cancer; Tumor microenvironment; Cancer stem cell; Intestinal stem cell
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions
(OpenAlex)
Sources: Web Of Science, ORCID
Added: March 4, 2024
2023 article
Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis (vol 49, pg 172, 2019)
Vales, S., Bacola, G., Biraud, M., Bessard, A., Geraldo, F., Dougherty, K. A., … Van Landeghem, L. (2023, February). EBIOMEDICINE, Vol. 88.
TL;DR:
This research attacked the mode of action of EMTs through a probabilistic route called “ ‘spiking’ the Tournaisian nervous system’ through a number of different mechanisms.
(via Semantic Scholar)
www.thelancet.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: February 27, 2023
2019 journal article
Nuclear envelope deformation controls cell cycle progression in response to mechanical force
EMBO REPORTS, 20(9).
author keywords: AP1; c-Jun; mechanotransduction; nuclear envelope; TEAD
MeSH headings : Cell Cycle / genetics; Cell Cycle / physiology; Cell Division / genetics; Cell Division / physiology; Cell Line; Cell Nucleus / genetics; Cell Nucleus / metabolism; Flow Cytometry; G1 Phase / genetics; G1 Phase / physiology; HeLa Cells; Humans; Mechanotransduction, Cellular / genetics; Mechanotransduction, Cellular / physiology; Microscopy, Atomic Force; Nuclear Envelope / genetics; Nuclear Envelope / metabolism; Plasmids / genetics; RNA, Small Interfering / genetics; RNA, Small Interfering / metabolism; S Phase / genetics; S Phase / physiology; Transcription Factors / genetics; Transcription Factors / metabolism
TL;DR:
It is shown that applying compressive force on the nucleus in the absence of myosin II‐mediated tension is sufficient to restore G1 to S transition and reveal that the nuclear envelope can operate as a mechanical sensor whose deformation controls cell growth in response to tension.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 19, 2019
2019 journal article
Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis.
EBioMedicine.
author keywords: Enteric glial cells; Colon cancer stem cells; Colorectal cancer: Tumor microenvironment; PGE2
MeSH headings : Animals; Carcinogenesis / metabolism; Carcinogenesis / pathology; Cell Line; Colonic Neoplasms / pathology; Dinoprostone / metabolism; Epithelial Cells / metabolism; Epithelial Cells / pathology; Female; Humans; Interleukin-1 / metabolism; Male; Mice, SCID; Models, Biological; Neoplastic Stem Cells / metabolism; Neoplastic Stem Cells / pathology; Neuroglia / pathology; Phenotype; Receptors, Prostaglandin E, EP4 Subtype / metabolism; Signal Transduction; Tumor Microenvironment
TL;DR:
Results show that EGCs, once activated by the tumor, acquire a pro-tumorigenic phenotype and stimulate CSC-driven tumorigenesis via a PGE2/EP4/EGFR-dependent pathway.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: ORCID
Added: December 3, 2019
Employment
Updated: December 2nd, 2019 11:00
2017 - present
North Carolina State University Raleigh, NC, US
Graduate Research Assistant
Molecular Biomedical Sciences
Education
Updated: December 2nd, 2019 11:01
2012 - 2017
North Carolina State University Raleigh, North Carolina, US
Bachelor of Science
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