Gregory Robert Bacola

Works (4)

Updated: April 23rd, 2025 20:48

2023 article

Erratum to “Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis” [EBioMedicine 49 (2019) 172–188]

Valès, S., Bacola, G., Biraud, M., Touvron, M., Bessard, A., Geraldo, F., … Landeghem, L. V. (2023, January 21). EBioMedicine, Vol. 88.

By: S. Valès *, G. Bacola n , M. Biraud*, M. Touvron  n, A. Bessard*, F. Geraldo*, K. Dougherty n, S. Lashani n ...

topics (OpenAlex): Cancer Research and Treatments; Cancer Cells and Metastasis; Epigenetics and DNA Methylation
TL;DR: This research attacked the mode of action of EMTs through a probabilistic route called “ ‘spiking’ the Tournaisian nervous system’ through a number of different mechanisms. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 27, 2023

2023 article

Mini-Review: Enteric glia of the tumor microenvironment: An affair of corruption

Mariant, C. L., Bacola, G., & Landeghem, L. V. (2023, August 10). Neuroscience Letters, Vol. 814.

By: C. Mariant n, G. Bacola n  & L. Landeghem n

author keywords: Enteric glial cell; Colon cancer; Tumor microenvironment; Cancer stem cell; Intestinal stem cell
MeSH headings : Humans; Neuroglia / metabolism; Enteric Nervous System; Neurons; Colonic Neoplasms / metabolism; Colonic Neoplasms / pathology; Carcinogenesis; Tumor Microenvironment
topics (OpenAlex): Gastrointestinal motility and disorders; Helicobacter pylori-related gastroenterology studies; Cancer Cells and Metastasis
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 4, 2024

2019 article

Nuclear envelope deformation controls cell cycle progression in response to mechanical force

Aureille, J., Buffière‐Ribot, V., Harvey, B. E., Boyault, C., Pernet, L., Andersen, T., … Guilluy, C. (2019, August 1). EMBO Reports.

By: J. Aureille *, V. Buffière‐Ribot*, B. Harvey*, C. Boyault *, L. Pernet *, T. Andersen *, G. Bacola n , M. Balland * ...

author keywords: AP1; c-Jun; mechanotransduction; nuclear envelope; TEAD
MeSH headings : Cell Cycle / genetics; Cell Cycle / physiology; Cell Division / genetics; Cell Division / physiology; Cell Line; Cell Nucleus / genetics; Cell Nucleus / metabolism; Flow Cytometry; G1 Phase / genetics; G1 Phase / physiology; HeLa Cells; Humans; Mechanotransduction, Cellular / genetics; Mechanotransduction, Cellular / physiology; Microscopy, Atomic Force; Nuclear Envelope / genetics; Nuclear Envelope / metabolism; Plasmids / genetics; RNA, Small Interfering / genetics; RNA, Small Interfering / metabolism; S Phase / genetics; S Phase / physiology; Transcription Factors / genetics; Transcription Factors / metabolism
topics (OpenAlex): Nuclear Structure and Function; Cellular Mechanics and Interactions; RNA Research and Splicing
TL;DR: It is shown that applying compressive force on the nucleus in the absence of myosin II‐mediated tension is sufficient to restore G1 to S transition and reveal that the nuclear envelope can operate as a mechanical sensor whose deformation controls cell growth in response to tension. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: August 19, 2019

2019 article

Tumor cells hijack enteric glia to activate colon cancer stem cells and stimulate tumorigenesis

Valès, S., Bacola, G., Biraud, M., Touvron, M., Bessard, A., Geraldo, F., … Landeghem, L. V. (2019, October 26). EBioMedicine.

By: S. Valès *, G. Bacola n , M. Biraud*, M. Touvron  n, A. Bessard*, F. Geraldo*, K. Dougherty n, S. Lashani n ...

author keywords: Enteric glial cells; Colon cancer stem cells; Colorectal cancer: Tumor microenvironment; PGE2
MeSH headings : Animals; Carcinogenesis / metabolism; Carcinogenesis / pathology; Cell Line; Colonic Neoplasms / pathology; Dinoprostone / metabolism; Epithelial Cells / metabolism; Epithelial Cells / pathology; Female; Humans; Interleukin-1 / metabolism; Male; Mice, SCID; Models, Biological; Neoplastic Stem Cells / metabolism; Neoplastic Stem Cells / pathology; Neuroglia / pathology; Phenotype; Receptors, Prostaglandin E, EP4 Subtype / metabolism; Signal Transduction; Tumor Microenvironment
topics (OpenAlex): Cancer Cells and Metastasis; Cancer, Stress, Anesthesia, and Immune Response; Cancer Research and Treatments
TL;DR: Results show that EGCs, once activated by the tumor, acquire a pro-tumorigenic phenotype and stimulate CSC-driven tumorigenesis via a PGE2/EP4/EGFR-dependent pathway. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: December 3, 2019

Employment

Updated: December 2nd, 2019 11:00

2017 - present

North Carolina State University Raleigh, NC, US
Graduate Research Assistant Molecular Biomedical Sciences

Education

Updated: December 2nd, 2019 11:01

2012 - 2017

North Carolina State University Raleigh, North Carolina, US
Bachelor of Science

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2026) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.