Works (195)
Updated: September 13th, 2023 05:01
2023 journal article
Astaxanthin supplementation counters exercise-induced decreases in immune-related plasma proteins
FRONTIERS IN NUTRITION, 10.
author keywords: astaxanthin; exercise; proteomics; oxylipins; inflammation; cytokines
www.frontiersin.org (publisher PDF)
Sources: Web Of Science, ORCID
Added: April 17, 2023
2023 review
Blueberry Supplementation and Skin Health
[Review of ]. ANTIOXIDANTS, 12(6).
author keywords: blueberries; skin; inflammation; polyphenol; antioxidant
Sources: Web Of Science, ORCID
Added: June 14, 2023
2023 article
CADMIUM EXPOSURE AFFECTS THE PROGRESSION OF HUMAN METASTATIC MELANOMA BY INDUCING A DEREGULATION OF ANTIOXIDANT CELL RESPONSE
Casoni, A., Benedusi, M., Cervellati, F., Pecorelli, A., Ferrara, F., Vallese, A., & Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 42–43.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2023 article
CONSTITUTIVE ACTIVATION OF NLRP3 INFLAMMASOME MACHINERY IN EX-VIVO MODELS OF RETT SYNDROME: FROM PATHOGENETIC ROLE TO NEW POTENTIAL THERAPEUTIC TARGET
Cordone, V., Pecorelli, A., Ferrara, F., Guiotto, A., Hayek, J., Cervellati, C., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 12–12.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2023 article
Caffeic acid-loaded lipid nanoparticles as a tool to protect skin against oxidative stress: formulation and evaluation on human skin explants
Sguizzato, M., Ferrara, F., Valacchi, G., Cortesi, R., & Esposito, E. (2023, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 198, pp. S19–S19.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2023 article
Deregulated NLRP3 inflammasome response due to a constitutive activation of NF-kappa B p65 pro-inflammatory pathway in lymphomonocytes of Rett syndrome patients
Cordone, V., Vallese, A., Pecorelli, A., Guiotto, A., Ferrara, F., Benedusi, M., … Valacchi, G. (2023, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 198, pp. S21–S22.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2023 journal article
Development of Spray Dried Spirulina Protein-Berry Pomace Polyphenol Particles to Attenuate Pollution-Induced Skin Damage: A Convergent Food-Beauty Approach
ANTIOXIDANTS, 12(7).
author keywords: sustainability; value-added; repurposing; skin health; cosmeceuticals
Sources: Web Of Science, ORCID
Added: July 17, 2023
2023 article
Editorial: Cell cycle control as a new therapeutic approach for SARS-CoV-2 infection
Rizzo, R., Caccuri, F., Valacchi, G., & Zauli, G. (2023, February 1). FRONTIERS IN PHARMACOLOGY, Vol. 14.
author keywords: cell cycle; SARS-CoV-2; p53; cytokine storm; idasanutlin
Sources: Web Of Science, ORCID
Added: March 13, 2023
2023 journal article
Evaluation of Anti-Oxinflammatory and ACE-Inhibitory Properties of Protein Hydrolysates Obtained from Edible Non-Mulberry Silkworm Pupae (Antheraea assama and Philosomia ricinii)
NUTRIENTS, 15(4).
author keywords: non-mulberry silkworm pupae; angiotensin converting enzyme-inhibitory peptides; antioxidative peptides; ultrafiltration; anti-inflammatory peptides
MeSH headings : Animals; Angiotensin-Converting Enzyme Inhibitors / pharmacology; Antioxidants / pharmacology; Protein Hydrolysates / pharmacology; Bombyx; Pupa; Endothelial Cells; Lipopolysaccharides; Peptides / pharmacology; Hypertension; Hydrolysis
Sources: Web Of Science, ORCID
Added: March 20, 2023
2023 article
INFLAMMASOMES REGULATION BY ENVIRONMENTAL POLLUTANTS IN HUMAN SKIN
Ferrara, F., Pecorelli, A., Guiotto, A., Vallese, A., Cordone, V., Benedusi, M., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 38–39.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2023 journal article
Identification of bromelain subfamily proteases encoded in the pineapple genome
SCIENTIFIC REPORTS, 13(1).
Sources: Web Of Science, ORCID
Added: August 21, 2023
2023 article
MITOCHONDRIAL DYSFUNCTION AND NLRP3 INFLAMMASOME ACTIVATION IN AUTISM SPECTRUM DISORDER
Vallese, A., Pecorelli, A., Cordone, V., Ferrara, F., Benedusi, M., Cervellati, F., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 20–20.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2023 review
Moderate red wine intake and cardiovascular health protection: a literature review
[Review of ]. FOOD & FUNCTION, 14(14), 6346–6362.
MeSH headings : Male; Humans; Female; Wine / analysis; Cardiovascular Diseases / prevention & control; Alcoholic Beverages; Cardiovascular System; Antioxidants; Ethanol; Alcohol Drinking
Sources: Web Of Science, ORCID
Added: July 24, 2023
2023 journal article
Modulation of Cutaneous Carotenoid Content via Ozone Exposure
COSMETICS, 10(4).
author keywords: skin barrier; carotenoids; ozone exposure; Raman spectroscopy; statistics
Sources: Web Of Science, ORCID
Added: September 11, 2023
2023 journal article
Ox-inflammasome involvement in neuroinflammation
FREE RADICAL BIOLOGY AND MEDICINE, 207, 161–177.
Sources: Web Of Science, ORCID
Added: September 5, 2023
2023 article
ROLE OF COENZYME Q10 IN MITOCHONDRIAL DYSFUNCTION AND OXIDATIVE DAMAGE IN RETT SYNDROME
Silvestri, S., Marcheggiani, F., Orlando, P., Cirilli, I., Mengarelli, F., Vallese, A., … Tiano, L. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 16–16.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2023 article
THE POSSIBLE MODULATION OF NRF2 AND NF-KB CROSSTALK BY SULFORAPHANE IN THE PROGRESSION OF HUMAN MELANOMA
Benedusi, M., Canella, R., Vallese, A., Casoni, A., Guerra, M., Rispoli, G., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 57–57.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2023 article
THE PROTECTIVE ROLE OF ENDOTHELIAL alpha 1AMPK IN AIRCRAFT NOISE-INDUCED VASCULAR DYSFUNCTION AND OXIDATIVE STRESS IS MEDIATED BY FASTING, EXERCISE AND PHARMACOLOGICAL TREATMENT
Cordone, V., Pecorelli, A., Ferrara, F., Guiotto, A., Hayek, J., Cervellati, C., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 11–12.
Sources: Web Of Science, ORCID
Added: June 19, 2023
2022 article
Aberrant Mitochondrial Bioenergetics Fuels Inflammasome Machinery in Autism Spectrum Disorder
Pecorelli, A., Francesca, F., Cordone, V., Guiotto, A., Cervellati, C., Hayek, J., & Valacchi, G. (2022, February 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 180, pp. 97–98.
Sources: Web Of Science, ORCID
Added: April 25, 2022
2022 journal article
Biological activity of new bioactive steroids deriving from biotransformation of cortisone
MICROBIAL CELL FACTORIES, 21(1).
author keywords: Biotransformations; Cortisone; Steroids; Neuroprotective; Anti-inflammatory; Antioxidant
MeSH headings : Cortisone; Antioxidants / pharmacology; Biotransformation; Steroids; Anti-Inflammatory Agents / pharmacology; Anti-Inflammatory Agents / therapeutic use
Sources: Web Of Science, ORCID
Added: December 5, 2022
2022 journal article
Chemoresistive Sensors for Cellular Type Discrimination Based on Their Exhalations
NANOMATERIALS, 12(7).
author keywords: chemoresistivity; nanostructures; sensors; cells; tumor; VOCs
Sources: Web Of Science, ORCID
Added: April 25, 2022
2022 journal article
Dimethyl Fumarate-Loaded Transethosomes: A Formulative Study and Preliminary Ex Vivo and In Vivo Evaluation
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(15).
author keywords: dimethyl fumarate; cryogenic transmission electron microscopy; wound healing; transethosomes; transdermal delivery
MeSH headings : Administration, Cutaneous; Dimethyl Fumarate / pharmacology; Drug Delivery Systems / methods; Humans; Liposomes / chemistry; Phosphatidylcholines / metabolism; Skin / metabolism; Skin Absorption
Sources: Web Of Science, ORCID
Added: August 29, 2022
2022 article
Editorial: Angiogenesis and Nutraceuticals
Trabalzini, L., Tundis, R., Valacchi, G., Evelson, P. A., & Finetti, F. (2022, May 30). FRONTIERS IN PHARMACOLOGY, Vol. 13.
author keywords: angiogenesis; nutraceuticals; endothelial cells; foods; food-derived products
Sources: Web Of Science, ORCID
Added: June 20, 2022
2022 journal article
Ethosomes and Transethosomes as Cutaneous Delivery Systems for Quercetin: A Preliminary Study on Melanoma Cells
PHARMACEUTICS, 14(5).
author keywords: quercetin; ethosome; transethosome; in vitro release test; in vitro permeation test; Franz cell; wound healing; migration assay
Sources: Web Of Science, ORCID
Added: June 13, 2022
2022 journal article
Extra Virgin Olive Oil Extracts of Indigenous Southern Tuscany Cultivar Act as Anti-Inflammatory and Vasorelaxant Nutraceuticals
ANTIOXIDANTS, 11(3).
author keywords: olive oil; traceability quality; food origin; luteolin; oleuropein; CaCo-2 cells; Nrf2; NF-kappa B
Sources: Web Of Science, ORCID
Added: April 18, 2022
2022 article
Inflammasome involvement in CS-induced damage in HaCaT keratinocytes
Prieux, R., Ferrara, F., Cervellati, F., Guiotto, A., Benedusi, M., & Valacchi, G. (2022, April 15). IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, Vol. 4.
MeSH headings : Animals; Cytokines / metabolism; Inflammasomes / metabolism; Interleukin-1beta / metabolism; Keratinocytes / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Skin / metabolism
Sources: Web Of Science, ORCID
Added: May 2, 2022
2022 article
Involvement Of Ferroptosis In Rett Syndrome
Guiotto, A., Cordone, V., Benedusi, M., Cervellati, F., Cervellati, C., Hayek, J., … Pecorelli, A. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.
Sources: Web Of Science, ORCID
Added: March 6, 2023
2022 article
Loss of Scavenger Receptor B1 (SR-B1) in Brain of a Rett Syndrome Mouse Model
Pecorelli, A., Ferrara, F., Guiotto, A., Vallese, A., Cordone, V., Belmonte, G., … Valacchi, G. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.
Sources: Web Of Science, ORCID
Added: March 6, 2023
2022 journal article
MicroRNA Alterations Induced in Human Skin by Diesel Fumes, Ozone, and UV Radiation
JOURNAL OF PERSONALIZED MEDICINE, 12(2).
author keywords: microRNAs; environmental risk factors; cutaneous tissues; ozone exposure
Sources: Web Of Science, ORCID
Added: April 4, 2022
2022 article
Mutations Specific Redox Regulation Pathway In Rett Syndrome By The Use Of Transcriptomics And Proteomics Approaches
Pasqui, A., Cicaloni, V., Tinti, L., Mori, A., Bruttini, M., Pecorelli, A., … Valacchi, G. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.
Sources: Web Of Science, ORCID
Added: March 6, 2023
2022 review
Oxidative-Stress-Sensitive microRNAs in UV-Promoted Development of Melanoma
[Review of ]. CANCERS, 14(13).
author keywords: skin cancer; sunlight; redox imbalance; miRNome; mutations; epigenome
Sources: Web Of Science, ORCID
Added: July 26, 2022
2022 journal article
The constitutive activation of TLR4-IRAK1-NF kappa B axis is involved in the early NLRP3 inflammasome response in peripheral blood mononuclear cells of Rett syndrome patients
FREE RADICAL BIOLOGY AND MEDICINE, 181, 1–13.
author keywords: MeCP2; p65; Oxinflammation; Interleukin-18; Interleukin-1 beta
MeSH headings : Humans; Inflammasomes / genetics; Inflammasomes / metabolism; Interleukin-1 Receptor-Associated Kinases / genetics; Interleukin-1beta / genetics; Interleukin-1beta / metabolism; Leukocytes, Mononuclear / metabolism; NF-kappa B / genetics; NF-kappa B / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / genetics; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Rett Syndrome / genetics; Rett Syndrome / metabolism; Toll-Like Receptor 4 / genetics
Sources: Web Of Science, ORCID
Added: March 14, 2022
2022 journal article
Ubiquitination as a key regulatory mechanism for O-3-induced cutaneous redox inflammasome activation
REDOX BIOLOGY, 56.
Contriutors: F. Ferrara*, V. Cordone *, A. Pecorelli* , M. Benedusi *, E. Pambianchi*, A. Guiotto*, A. Vallese* , F. Cervellati *, *
author keywords: Inflammasomes; OxInflammation; Proteasome; UBR2; N-end rule pathway
MeSH headings : Adaptor Proteins, Signal Transducing / metabolism; Air Pollutants; Apoptosis Regulatory Proteins / genetics; Catalase / metabolism; Cytokines / metabolism; Environmental Pollutants; Humans; Hydrogen Peroxide / metabolism; Inflammasomes / metabolism; NLR Proteins / metabolism; Oxidation-Reduction; Ozone / metabolism; Particulate Matter; Reactive Oxygen Species / metabolism; Ubiquitin-Protein Ligases / metabolism; Ubiquitination
Sources: Web Of Science, ORCID
Added: September 12, 2022
2022 article
Ubiquitination as a key regulatory mechanism for O3-induced cutaneous redox Inflammasome activation
Ferrara, F., Cordone, V., Pecorelli, A., Benedusi, M., Pambianchi, E., Guiotto, A., … Valacchi, G. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.
Sources: Web Of Science, ORCID
Added: March 6, 2023
2022 review
Ultraviolet Light Protection: Is It Really Enough?
[Review of ]. ANTIOXIDANTS, 11(8).
author keywords: skin aging; ultraviolet light; solar radiation; pollution; reactive oxygen species; oxidative stress; antioxidants; chelators
Sources: Web Of Science, ORCID
Added: September 6, 2022
2021 journal article
"Plurethosome" as Vesicular System for Cutaneous Administration of Mangiferin: Formulative Study and 3D Skin Tissue Evaluation
PHARMACEUTICS, 13(8).
author keywords: phosphatidylcholine; poloxamer; mangiferin; in vitro diffusion; antioxidant
Sources: Web Of Science, ORCID
Added: September 7, 2021
2021 journal article
Alaskan Bog Blueberry (Vaccinium uliginosum) Extract as an Innovative Topical Approach to Prevent UV-Induced Skin Damage
COSMETICS, 8(4).
author keywords: cosmeceuticals; environmental stressor; oxidation; inflammation; antioxidant; OxInflammation; phytochemicals
Sources: Web Of Science, ORCID
Added: December 2, 2021
2021 article
Alteration of cellular defensive response and a possible involvement of ferroptosis cell death in Rett syndrome disorder
Guiotto, A., Cordone, V., Benedusi, M., Cervellati, F., Hayek, J., Cervellati, C., … Pecorelli, A. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.
Sources: Web Of Science, ORCID
Added: April 5, 2021
2021 journal article
Alterations in oxygen metabolism are associated to lung toxicity triggered by silver nanoparticles exposure
FREE RADICAL BIOLOGY AND MEDICINE, 166, 324–336.
author keywords: Nanoparticles; Lung epithelium; Nanotoxicology; Oxidative metabolism; NADPH oxidase; Mitochondria
MeSH headings : Animals; Hydrogen Peroxide; Lung; Metal Nanoparticles / toxicity; Mice; Oxygen; Silver
Sources: Web Of Science, ORCID
Added: April 19, 2021
2021 review
Altered Bone Status in Rett Syndrome
[Review of ]. LIFE-BASEL, 11(6).
author keywords: MeCP2; bone mineral density; bone metabolism; osteoblast; WNT pathway
Sources: Web Of Science, ORCID
Added: July 12, 2021
2021 article
BACE1 role in Alzheimer's disease and other dementias: from the theory to the practice
Cervellati, C., Valacchi, G., & Zuliani, G. (2021, December). NEURAL REGENERATION RESEARCH, Vol. 16, pp. 2407–2408.
Sources: Web Of Science, ORCID
Added: June 10, 2021
2021 review
Bench approaches to study the detrimental cutaneous impact of tropospheric ozone
[Review of ]. JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, 31(1), 137–148.
author keywords: Environmental pollution; Skin; 3D skin tissue model; Oxidative stress; Skin protection
MeSH headings : Air Pollutants / adverse effects; Air Pollutants / analysis; Cities; Humans; Lipid Peroxidation; Oxidative Stress; Ozone / adverse effects; Ozone / analysis; Skin / metabolism
Sources: Web Of Science, ORCID
Added: November 24, 2020
2021 journal article
Circadian Deregulation as Possible New Player in Pollution-Induced Tissue Damage
ATMOSPHERE, 12(1).
author keywords: circadian clock; pollution; antioxidant system
Sources: Web Of Science, ORCID
Added: February 15, 2021
2021 review
Connection between the Altered HDL Antioxidant and Anti-Inflammatory Properties and the Risk to Develop Alzheimer's Disease: A Narrative Review
[Review of ]. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2021.
MeSH headings : Alzheimer Disease / etiology; Alzheimer Disease / metabolism; Alzheimer Disease / pathology; Animals; Anti-Inflammatory Agents / metabolism; Antioxidants / metabolism; Humans; Inflammation / complications; Lipoproteins, HDL / metabolism; Oxidative Stress
Sources: Web Of Science, ORCID
Added: February 22, 2021
2021 journal article
Cultivating a Three-dimensional Reconstructed Human Epidermis at a Large Scale
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 5(171).
MeSH headings : Cell Differentiation; Cells, Cultured; Coculture Techniques; Epidermal Cells; Epidermis; Filaggrin Proteins; Humans; Keratinocytes; Skin
Sources: Web Of Science, ORCID
Added: June 21, 2021
2021 journal article
Deferoxamine Treatment Improves Antioxidant Cosmeceutical Formulation Protection against Cutaneous Diesel Engine Exhaust Exposure
ANTIOXIDANTS, 10(12).
author keywords: cosmeceuticals; pollution; iron-chelator
Sources: Web Of Science, ORCID
Added: January 24, 2022
2021 article
Deregulated inflammasome response in Rett syndrome
Cordone, V., Pecorelli, A., Falone, S., Hayek, J., Amicarelli, F., & Valacchi, G. (2021, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 177.
Sources: Web Of Science, ORCID
Added: February 21, 2022
2021 journal article
Ethosomes and Transethosomes for Mangiferin Transdermal Delivery
ANTIOXIDANTS, 10(5).
author keywords: ethosomes; transethosomes; mangiferin; franz cell; antioxidants
Sources: Web Of Science, ORCID
Added: June 10, 2021
2021 journal article
Formulative Study and Intracellular Fate Evaluation of Ethosomes and Transethosomes for Vitamin D3 Delivery
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(10).
author keywords: cell culture; cholecalciferol; cryogenic transmission electron microscopy; in vitro test; light microscopy; lipid nanocarriers; transmission electron microscopy
MeSH headings : Cell Line; Chemistry, Pharmaceutical / methods; Cholecalciferol / administration & dosage; Cholecalciferol / metabolism; Cholecalciferol / pharmacology; Drug Carriers / chemistry; Drug Delivery Systems / methods; Fibroblasts / drug effects; Humans; Keratinocytes / drug effects; Lipids / chemistry; Liposomes / chemistry; Myoblasts / drug effects; Nanocapsules / chemistry; Pilot Projects; Skin / metabolism; Skin Absorption; Surface-Active Agents / metabolism
Sources: Web Of Science, ORCID
Added: June 28, 2021
2021 journal article
Impaired mitochondrial quality control in Rett Syndrome
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 700.
author keywords: RTT Syndrome; Oxidative stress; Mitochondrial quality control; Mitophagy; Apoptosis
MeSH headings : Adolescent; Adult; Apoptosis; Caspase 3 / genetics; Caspase 3 / metabolism; Caspase 7 / genetics; Caspase 7 / metabolism; Child; Dynamins / genetics; Dynamins / metabolism; Female; Fibroblasts / metabolism; Fibroblasts / pathology; GTP Phosphohydrolases / genetics; GTP Phosphohydrolases / metabolism; Humans; Membrane Proteins / genetics; Membrane Proteins / metabolism; Methyl-CpG-Binding Protein 2 / genetics; Methyl-CpG-Binding Protein 2 / metabolism; Mitochondria / genetics; Mitochondria / metabolism; Mitochondria / pathology; Mitochondrial Membrane Transport Proteins / genetics; Mitochondrial Membrane Transport Proteins / metabolism; Mitochondrial Proteins / genetics; Mitochondrial Proteins / metabolism; Mitophagy; Oxidation-Reduction; Rett Syndrome / genetics; Rett Syndrome / metabolism; Rett Syndrome / pathology
Sources: Web Of Science, ORCID
Added: March 15, 2021
2021 article
Improper enzymatic defensive responses in Rett syndrome disorder
Guiotto, A., Cordone, V., Benedusi, M., Cervellati, F., Hayek, J., Cervellati, C., … Pecorelli, A. (2021, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 177.
Sources: Web Of Science, ORCID
Added: February 21, 2022
2021 journal article
Inflammasome Activation in Pollution-Induced Skin Conditions
PLASTIC AND RECONSTRUCTIVE SURGERY, 147(1S-2), 15S–24S.
MeSH headings : Air Pollutants / adverse effects; Air Pollution / adverse effects; Animals; Dermatitis / immunology; Dermatitis / pathology; Dermatitis / prevention & control; Disease Models, Animal; Environmental Exposure / adverse effects; Furans; Heterocyclic Compounds, 4 or More Rings / pharmacology; Heterocyclic Compounds, 4 or More Rings / therapeutic use; Humans; Indenes; Inflammasomes / antagonists & inhibitors; Inflammasomes / immunology; Inflammasomes / metabolism; Interleukin-18 / metabolism; Interleukin-1beta / metabolism; Mice; NLR Family, Pyrin Domain-Containing 3 Protein / antagonists & inhibitors; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Nitriles / pharmacology; Nitriles / therapeutic use; Skin / drug effects; Skin / immunology; Skin / pathology; Skin Aging / immunology; Sulfonamides; Sulfones / pharmacology; Sulfones / therapeutic use
Sources: Web Of Science, ORCID
Added: July 6, 2021
2021 article
Mitochondrial dynamics and quality control pathways impairment in Rett Syndrome and Autism Spectrum Disorder
Pecorelli, A., Guiotto, A., Cordone, V., Cervellati, F., Benedusi, M., Cervellati, C., … Valacchi, G. (2021, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 177, pp. S17–S18.
Sources: Web Of Science, ORCID
Added: February 28, 2022
2021 article
Mitochondrial dysfunction fuels inflammasome machinery in Autism Spectrum Disorder
Pecorelli, A., Cordone, V., Guiotto, A., Cervellati, F., Benedusi, M., Cervellati, C., … Valacchi, G. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.
Sources: Web Of Science, ORCID
Added: April 5, 2021
2021 article
NALP1 involvement in cigarette smoke induces cutaneous inflammation
Prieux, R., Benedusi, M., Ferrara, F., Guiotto, A., Cervellati, F., & Valacchi, G. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.
Sources: Web Of Science, ORCID
Added: April 5, 2021
2021 journal article
Novel Spray Dried Algae-Rosemary Particles Attenuate Pollution-Induced Skin Damage
MOLECULES, 26(13).
author keywords: cosmeceuticals; pollution; phytochemicals; herbs
MeSH headings : Antioxidants / chemistry; Antioxidants / pharmacology; Cells, Cultured; Chlorella / chemistry; Cinnamates / chemistry; Depsides / chemistry; Environmental Exposure / adverse effects; Filaggrin Proteins; Humans; Rosmarinus / chemistry; Skin / injuries; Skin / metabolism; Skin / pathology; Skin Aging / drug effects
Sources: Web Of Science, ORCID
Added: June 23, 2021
2021 journal article
Oxidative metabolism in the cardiorespiratory system after an acute exposure to nickel-doped nanoparticles in mice
TOXICOLOGY, 464.
author keywords: nanoparticles; nickel; reactive oxygen species; oxidative stress; NADPH oxidase
MeSH headings : Animals; Antioxidants / metabolism; Female; Lung / drug effects; Lung / metabolism; Male; Metal Nanoparticles / chemistry; Metal Nanoparticles / toxicity; Mice; Mitochondria / drug effects; Nickel / chemistry; Oxidation-Reduction / drug effects; Oxidative Stress / drug effects; Oxygen Consumption / drug effects; Silicon Dioxide / chemistry
Sources: Web Of Science, ORCID
Added: November 29, 2021
2021 article
Proteome composition and profiling of bioactive peptides of edible Antheraea assamensis pupae by sequential enzymatic digestion and kinetic modeling of in vitro gastrointestinal digestion
Sarkar, P., Valacchi, G., & Duary, R. K. (2021, October 28). EUROPEAN FOOD RESEARCH AND TECHNOLOGY, Vol. 10.
author keywords: Insect hydrolysate; Papain; Thermolysin; Gastrointestinal digestion; Free amino acids; Enzyme kinetics
Sources: Web Of Science, ORCID
Added: November 8, 2021
2021 review
SARS-CoV-2 infection, COVID-19 pathogenesis, and exposure to air pollution: What is the connection?
[Review of ]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1486(1), 15–38.
author keywords: air pollution; coronavirus; particulate matter; ozone; nitrogen dioxide; viral infection
MeSH headings : Adaptive Immunity; Air Pollutants / adverse effects; Air Pollution / adverse effects; COVID-19 / etiology; COVID-19 / immunology; COVID-19 / virology; Host Microbial Interactions; Humans; Immunity, Innate; Models, Biological; Pandemics; Particulate Matter / adverse effects; Receptors, Virus / physiology; Respiratory System / physiopathology; SARS-CoV-2 / immunology; SARS-CoV-2 / pathogenicity; SARS-CoV-2 / physiology; Toll-Like Receptors / physiology; Virus Internalization; Virus Replication
Sources: Web Of Science, ORCID
Added: October 19, 2020
2021 journal article
Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents
ACS CHEMICAL NEUROSCIENCE, 12(9), 1716–1736.
author keywords: Endocannabinoid system; fatty acid amide hydrolase; enzyme inhibitors; selective inhibitors; epilepsy; temporal lobe epilepsy; seizures
MeSH headings : Amidohydrolases; Anticonvulsants / pharmacology; Endocannabinoids; Enzyme Inhibitors / pharmacology; Humans; Seizures
Sources: Web Of Science, ORCID
Added: June 10, 2021
2021 article
The role of pulmonary ORCC and CLC-2 channels in the response to oxidative stress
Canella, R., Benedusi, M., Martini, M., Guiotto, A., Cervellati, F., & Valacchi, G. (2021, May 7). MOLECULAR & CELLULAR TOXICOLOGY, Vol. 5.
author keywords: Human lung epithelial cells; Chloride channels; Ozone; Oxidative stress; Patch clamp technique
Sources: Web Of Science, ORCID
Added: June 10, 2021
2021 article
Ubiquitination as a key regulatory mechanism for O-3-induced cutaneous redox inflammasome activation
Ferrara, F., Pecorelli, A., Benedusi, M., Pambianchi, E., Guiotto, A., Cervellati, F., & Valacchi, G. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.
Sources: Web Of Science, ORCID
Added: April 5, 2021
2020 journal article
A proteomics approach to further highlight the altered inflammatory condition in Rett syndrome
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 696.
author keywords: Rare disease; Rett syndrome; Inflammatory status; NLRP3 inflammasome; Mass spectrometry-based proteomics
MeSH headings : Adult; Female; Fibroblasts / chemistry; Humans; Inflammation / complications; Inflammation / metabolism; Protein Interaction Maps; Proteome / analysis; Proteome / metabolism; Proteomics; Rett Syndrome / complications; Rett Syndrome / metabolism; Young Adult
Sources: Web Of Science, ORCID
Added: January 19, 2021
2020 journal article
Alterations of mitochondrial bioenergetics, dynamics, and morphology support the theory of oxidative damage involvement in autism spectrum disorder
FASEB JOURNAL, 34(5), 6521–6538.
author keywords: 4-hydroxynonenal; fission; fusion; mitophagy; nuclear factor erythroid 2-related factor 2
MeSH headings : Adolescent; Adult; Autism Spectrum Disorder / metabolism; Autism Spectrum Disorder / pathology; Case-Control Studies; Child; Energy Metabolism; Female; Fibroblasts / metabolism; Fibroblasts / pathology; Humans; Male; Mitochondria / metabolism; Mitochondria / pathology; Mitochondrial Dynamics; Mitochondrial Proteins / metabolism; Oxidative Stress; Young Adult
Sources: Web Of Science, ORCID
Added: April 20, 2020
2020 journal article
Altered inflammasome machinery as a key player in the perpetuation of Rett syndrome oxinflammation
REDOX BIOLOGY, 28.
author keywords: NLRP3; ASC; Inflammatory status; Cytokines; MeCP2
MeSH headings : Biomarkers; Cytokines / metabolism; Disease Susceptibility; Fibroblasts / metabolism; Fluorescent Antibody Technique; Humans; Inflammasomes / metabolism; Inflammation Mediators / metabolism; Interleukin-1beta / metabolism; NF-kappa B / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Protein Transport; Rett Syndrome / etiology; Rett Syndrome / metabolism
Sources: Web Of Science, ORCID
Added: December 30, 2019
2020 journal article
Circadian Clock and OxInflammation: Functional Crosstalk in Cutaneous Homeostasis
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2020.
MeSH headings : Cells, Cultured; Circadian Clocks / physiology; Homeostasis; Humans; Inflammation / metabolism; Inflammation / pathology; Keratinocytes / cytology; Keratinocytes / metabolism; Skin / metabolism; Skin / pathology
Sources: Web Of Science, ORCID
Added: May 26, 2020
2020 journal article
Defective proteasome biogenesis into skin fibroblasts isolated from Rett syndrome subjects with MeCP2 non-sense mutations
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1866(7).
author keywords: Rett syndrome; Skin primary fibroblasts; Proteasome; alpha-Ring; PAC1; PAC2
MeSH headings : Codon, Nonsense / genetics; Dual Specificity Phosphatase 2 / genetics; Fibroblasts / metabolism; Gene Expression Regulation; Genetic Diseases, X-Linked / genetics; Genetic Diseases, X-Linked / pathology; Humans; Methyl-CpG-Binding Protein 2 / genetics; Neurodevelopmental Disorders / genetics; Neurodevelopmental Disorders / pathology; Primary Cell Culture; Proteasome Endopeptidase Complex / genetics; Proteolysis; Rett Syndrome / genetics; Rett Syndrome / pathology; Skin / metabolism; Skin / pathology; Ubiquitin / genetics
Sources: Web Of Science, ORCID
Added: June 15, 2020
2020 journal article
Ethosomes for Coenzyme Q10 Cutaneous Administration: From Design to 3D Skin Tissue Evaluation
ANTIOXIDANTS, 9(6).
author keywords: ethosome; ubiquinone; H2O2; penetration enhancers; dermal administration; reconstituted human epidermis; small angle X-ray scattering
Sources: Web Of Science, ORCID
Added: August 10, 2020
2020 journal article
Gallic acid loaded poloxamer gel as new adjuvant strategy for melanoma: A preliminary study
COLLOIDS AND SURFACES B-BIOINTERFACES, 185.
author keywords: Biocompatible polymers; Polymer gels; In vitro diffusion; Polymer membranes; Gallic acid; Franz cell
MeSH headings : Adjuvants, Immunologic / pharmacology; Adjuvants, Immunologic / therapeutic use; Cell Line; Cell Movement / drug effects; Diffusion; Elasticity; Gallic Acid / pharmacology; Gallic Acid / therapeutic use; Gels / chemistry; Humans; Kinetics; Melanoma / drug therapy; Phase Transition; Poloxamer / chemistry; Rheology; Temperature; Viscosity; Wound Healing / drug effects
Sources: Web Of Science, ORCID
Added: January 13, 2020
2020 review
Impact of airborne particulate matter on skin: a systematic review from epidemiology to in vitro studies
[Review of ]. PARTICLE AND FIBRE TOXICOLOGY, 17(1).
author keywords: Particulate matter; Air pollution; Urban pollution; Skin models; Skin; In vitro studies; In vivo studies; Oxidative stress; Inflammation; Barrier dysfunction
MeSH headings : Air Pollutants / toxicity; Air Pollution; Humans; Oxidative Stress; Particulate Matter / toxicity; Reactive Oxygen Species; Skin / drug effects
Sources: Web Of Science, ORCID
Added: August 24, 2020
2020 journal article
Increased blood BACE1 activity as a potential common pathogenic factor of vascular dementia and late onset Alzheimer's disease
SCIENTIFIC REPORTS, 10(1).
MeSH headings : Aged; Aged, 80 and over; Alzheimer Disease / blood; Alzheimer Disease / diagnosis; Amyloid Precursor Protein Secretases / blood; Aspartic Acid Endopeptidases / blood; Dementia, Vascular / blood; Dementia, Vascular / diagnosis; Female; Humans; Male
Sources: Web Of Science, ORCID
Added: October 12, 2020
2020 journal article
Inflammation in Neurological Disorders: The Thin Boundary Between Brain and Periphery
ANTIOXIDANTS & REDOX SIGNALING, 33(3), 191–210.
author keywords: Alzheimer's disease; inflammation; multiple sclerosis; vascular dementia
MeSH headings : Animals; Biomarkers; Blood-Brain Barrier / metabolism; Brain / metabolism; Brain / pathology; Disease Susceptibility; Dysbiosis; Humans; Inflammation / etiology; Inflammation / metabolism; Inflammation / pathology; Nervous System Diseases / etiology; Nervous System Diseases / metabolism; Nervous System Diseases / pathology; Oxidative Stress; Peripheral Nerves / metabolism; Peripheral Nerves / pathology
Sources: Web Of Science, ORCID
Added: April 27, 2020
2020 journal article
KRIT1 as a possible new player in melanoma aggressiveness
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 691.
author keywords: KRIT1; Melanoma; Tumor suppressor; N-cadherin; Inflammation; beta-catenin
MeSH headings : Adult; Aged; Aged, 80 and over; Cell Line, Tumor; Cell Movement / physiology; Cell Nucleus / metabolism; Cell Proliferation / genetics; Down-Regulation; Female; Gene Knockdown Techniques / methods; Humans; KRIT1 Protein / genetics; KRIT1 Protein / metabolism; Male; Melanocytes / metabolism; Melanoma / metabolism; Melanoma / pathology; Middle Aged; beta Catenin / metabolism
Sources: Web Of Science, ORCID
Added: October 5, 2020
2020 journal article
Mechanisms involved in the unbalanced redox homeostasis in osteoblastic cellular model of Alkaptonuria
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 690.
author keywords: Alkaptonuria; Osteoblast; Oxidative stress; Nrf2; Mitochondria; NADPH oxidase
MeSH headings : Alkaptonuria / metabolism; Cell Line; DNA-Binding Proteins / metabolism; Homeostasis / physiology; Homogentisic Acid / metabolism; Humans; Hydrogen Peroxide / metabolism; Mitochondria / metabolism; Mitochondria / ultrastructure; NADPH Oxidases / metabolism; NF-E2-Related Factor 2 / metabolism; Osteoblasts / cytology; Oxidation-Reduction; Oxidative Stress / physiology; Signal Transduction; Superoxide Dismutase / metabolism; Thioredoxins / metabolism
Sources: Web Of Science, ORCID
Added: January 19, 2021
2020 review
Mimicking cigarette smoke exposure to assess cutaneous toxicity
[Review of ]. TOXICOLOGY IN VITRO, 62.
author keywords: Cigarette smoke; Skin models; Inflammation; Oxidative stress; Psoriasis; Atopic dermatitis
MeSH headings : Animals; Humans; Skin / drug effects; Skin Diseases / chemically induced; Tobacco Products; Tobacco Smoke Pollution / adverse effects
Sources: Web Of Science, ORCID
Added: December 30, 2019
2020 journal article
Mixed Flavonoid Supplementation Attenuates Postexercise Plasma Levels of 4-Hydroxynonenal and Protein Carbonyls in Endurance Athletes
INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, 30(2), 112–119.
author keywords: inflammation exercise; oxidative stress; peripheral blood mononuclear cells
Sources: Web Of Science, ORCID
Added: July 6, 2020
2020 journal article
NADPH oxidase and mitochondria are relevant sources of superoxide anion in the oxinflammatory response of macrophages exposed to airborne particulate matter
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 205.
author keywords: Air pollution; Oxidative stress; Inflammation; Mitochondria; NADPH oxidase; Macrophages
MeSH headings : Air Pollutants / toxicity; Animals; Antioxidants / metabolism; Coal Ash / toxicity; Hydrogen Peroxide / metabolism; Inflammation; Macrophages, Alveolar / drug effects; Macrophages, Alveolar / immunology; Macrophages, Alveolar / metabolism; Mice; Mitochondria / drug effects; Mitochondria / immunology; Mitochondria / metabolism; NADPH Oxidases / metabolism; Oxidation-Reduction; Oxidative Stress / drug effects; Oxidative Stress / immunology; Particulate Matter / toxicity; RAW 264.7 Cells; Superoxides / metabolism; Tumor Necrosis Factor-alpha / metabolism
Sources: Web Of Science, ORCID
Added: November 16, 2020
2020 journal article
Nanoparticulate Gels for Cutaneous Administration of Caffeic Acid
NANOMATERIALS, 10(5).
author keywords: solid lipid nanoparticles; caffeic acid; poloxamer; small angle X-ray scattering; cigarette smoke
Sources: Web Of Science, ORCID
Added: July 13, 2020
2020 journal article
Particulate Matter Induces Tissue OxInflammation: From Mechanism to Damage
ANTIOXIDANTS & REDOX SIGNALING, 33(4), 308–326.
author keywords: oxidative stress; inflammation; particulate matter; air pollution
MeSH headings : Air Pollution / adverse effects; Animals; Cytokines / metabolism; Disease Susceptibility; Humans; Inflammation / etiology; Inflammation / metabolism; Inflammation / pathology; Inflammation Mediators / metabolism; Oxidation-Reduction; Oxidative Stress; Particulate Matter / adverse effects; Reactive Oxygen Species / metabolism
Sources: Web Of Science, ORCID
Added: July 13, 2020
2020 journal article
Postexercise Inflammasome Activation and IL-1 beta Production Mitigated by Flavonoid Supplementation in Cyclists
INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, 30(6), 396–404.
author keywords: cytokines; gasdermin D; IL-18; inflammation
Sources: Web Of Science, ORCID
Added: November 9, 2020
2020 journal article
Proteomic pro fi ling reveals mitochondrial alterations in Rett syndrome
FREE RADICAL BIOLOGY AND MEDICINE, 155, 37–48.
MeSH headings : Gene Expression Profiling; Humans; Methyl-CpG-Binding Protein 2 / genetics; Mutation; Proteome / genetics; Proteomics; Rett Syndrome / genetics
Sources: Web Of Science, ORCID
Added: July 6, 2020
2020 journal article
Redox regulation of cutaneous inflammasome by ozone exposure
FREE RADICAL BIOLOGY AND MEDICINE, 152, 561–570.
MeSH headings : Caspase 1 / metabolism; Humans; Hydrogen Peroxide; Inflammasomes / metabolism; Interleukin-1beta / genetics; Interleukin-1beta / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / genetics; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Oxidation-Reduction; Ozone / toxicity; Reactive Oxygen Species
Sources: Web Of Science, ORCID
Added: July 13, 2020
2020 journal article
Serum beta-secretase 1 (BACE1) activity as candidate biomarker for late-onset Alzheimer's disease
GEROSCIENCE, 42(1), 159–167.
author keywords: Late-onset Alzheimer's disease; Mild cognitive impairment; Mixed dementia; Blood-based biomarkers; BACE1
MeSH headings : Alzheimer Disease / diagnosis; Amyloid Precursor Protein Secretases; Amyloid beta-Peptides; Aspartic Acid Endopeptidases; Biomarkers; Humans
Sources: Web Of Science, ORCID
Added: March 16, 2020
2020 article
Skin Health from the Inside Out
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 11, Vol. 11, pp. 235–254.
author keywords: pollution; skin; diet; GI tract; inflammation; antioxidant; vitamins
MeSH headings : Antioxidants / metabolism; Humans; Reactive Oxygen Species / metabolism; Skin Physiological Phenomena
Sources: Web Of Science, ORCID
Added: April 27, 2020
2020 journal article
The PDE4 inhibitor CHF6001 affects keratinocyte proliferation via cellular redox pathways
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 685.
author keywords: NOX; NF-kappa B; Cyclin D1; Skin; p21
MeSH headings : Aldehydes / metabolism; Cell Line; Cell Proliferation / drug effects; Cell Survival / drug effects; Cyclin D1 / metabolism; Humans; Keratinocytes / drug effects; Lipid Peroxidation / drug effects; NADPH Oxidases / metabolism; Oxidative Stress / drug effects; Phosphodiesterase 4 Inhibitors / pharmacology; Phosphodiesterase 4 Inhibitors / toxicity; Psoriasis / drug therapy; Sulfonamides / pharmacology; Sulfonamides / toxicity; Transcription Factor RelA / metabolism; para-Aminobenzoates / pharmacology; para-Aminobenzoates / toxicity
Sources: Web Of Science, ORCID
Added: May 8, 2020
2019 journal article
13-HODE, 9-HODE and ALOX15 as potential players in Rett syndrome OxInflammation
FREE RADICAL BIOLOGY AND MEDICINE, 134, 598–603.
author keywords: Rett syndrome; Oxidative stress; Hydroxyoctadecadienoic acids; Inflammation; Omega-3 polyunsaturated fatty acids; Arachidonate 15-Lipoxygenase
MeSH headings : Adolescent; Adult; Arachidonate 15-Lipoxygenase / genetics; Arachidonate 15-Lipoxygenase / metabolism; Case-Control Studies; Child; Female; Humans; Inflammation / genetics; Inflammation / metabolism; Inflammation / pathology; Leukocytes, Mononuclear / metabolism; Linoleic Acids / metabolism; Linoleic Acids, Conjugated / metabolism; Male; Rett Syndrome / genetics; Rett Syndrome / metabolism; Rett Syndrome / pathology; Young Adult
Sources: Web Of Science, ORCID
Added: July 1, 2019
2019 journal article
Antiglycative Activity and RAGE Expression in Rett Syndrome
CELLS, 8(2).
author keywords: methylglyoxal; glyoxalases; advanced glycation end products; MeCP2; dicarbonyl stress; fibroblasts
MeSH headings : Adolescent; Adult; Antigens, Neoplasm / metabolism; Cell Survival / drug effects; Child; Female; Fibroblasts / drug effects; Fibroblasts / metabolism; Glycosylation; Humans; Lactoylglutathione Lyase / metabolism; Mitogen-Activated Protein Kinases / metabolism; Pyruvaldehyde / pharmacology; Rett Syndrome / metabolism; Rett Syndrome / pathology; Thiolester Hydrolases / metabolism; Young Adult
Sources: Web Of Science, ORCID
Added: March 25, 2019
2019 article
Blueberries Topical Application Prevents Ozone Induced Cutaneous Inflammasome Activation
Pambianchi, E., Francesca, F., Pecorelli, A., Woodby, B., Lila, M., & Valacchi, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S148–S148.
Sources: Web Of Science, ORCID
Added: December 2, 2019
2019 journal article
Bone status in relation to ambulatory performance in girls with Rett syndrome: a 10-year longitudinal study
PEDIATRIC RESEARCH, 85(5), 639–643.
MeSH headings : Absorptiometry, Photon; Adolescent; Bone Density; Bone and Bones / diagnostic imaging; Bone and Bones / physiology; Child; Child Nutrition Sciences; Child, Preschool; Cholecalciferol / administration & dosage; Disabled Persons; Female; Finger Phalanges / diagnostic imaging; Follow-Up Studies; Fractures, Bone / diagnostic imaging; Humans; Infant; Longitudinal Studies; Nutritional Status; Rett Syndrome / diagnostic imaging; Rett Syndrome / physiopathology; Surveys and Questionnaires; Ultrasonography; Vitamin D / blood; Walking
Sources: Web Of Science, ORCID
Added: April 9, 2019
2019 article
Comparing Skin Aging in Vitro Induced by External and Internal Cigarette Smoke Exposure
Prieux, R., Valacchi, G., Benedusi, M., & Cervellati, F. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S137–S137.
Sources: Web Of Science, ORCID
Added: December 2, 2019
2019 journal article
Conjugation of LasR Quorum-Sensing Inhibitors with Ciprofloxacin Decreases the Antibiotic Tolerance of P-aeruginosa Clinical Strains
JOURNAL OF CHEMISTRY, 2019.
Sources: Web Of Science, ORCID
Added: April 9, 2019
2019 journal article
Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 183.
author keywords: Endocannabinoid system; Fatty acid amide hydrolase; Enzyme inhibitors; Selective inhibitors; Dopamine ligands; Polypharmacology; Multitarget compounds; Dopamine receptor ligands
MeSH headings : Amidohydrolases / antagonists & inhibitors; Amidohydrolases / metabolism; Binding, Competitive; Cell Line; Cell Survival / drug effects; Dopamine / metabolism; Endocannabinoids / metabolism; Enzyme Inhibitors / chemistry; Enzyme Inhibitors / pharmacology; Humans; Ligands; Piperazines / chemistry; Piperazines / pharmacology; Pyrroles / chemistry; Pyrroles / pharmacology
Sources: Web Of Science, ORCID
Added: December 16, 2019
2019 review
Evaluating the link between Paraoxonase-1 levels and Alzheimer's disease development
[Review of ]. MINERVA MEDICA, 110(3), 238–250.
author keywords: PON1 protein, human; Alzheimer's disease; Oxidative stress
MeSH headings : Alzheimer Disease / blood; Alzheimer Disease / epidemiology; Alzheimer Disease / etiology; Aryldialkylphosphatase / blood; Humans
Sources: Web Of Science, ORCID
Added: May 6, 2019
2019 article
HGA Induces Oxidative Damage in an Ostcoblastic Cellular Model of Alkaptonuria: Sources and Mechanisms HGA Induces Oxidative Damage in an Osteoblastic Cellular Model of Alkaptonuria: Sources and Mechanisms
Schiavone, M. L., Pecorelli, A., Woodby, B., Ferrara, F., Santucci, A., & Valacchi, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S37–S38.
Sources: Web Of Science, ORCID
Added: December 2, 2019
2019 review
Involvement of 4-hydroxy-2-nonenal in pollution-induced skin damage
[Review of ]. BIOFACTORS, 45(4), 536–547.
author keywords: ozone; particulate matter; cigarette smoke; peroxidation
MeSH headings : Air Pollutants / metabolism; Air Pollutants / toxicity; Aldehydes / metabolism; Aldehydes / toxicity; Dermatitis, Atopic / chemically induced; Dermatitis, Atopic / genetics; Dermatitis, Atopic / metabolism; Dermatitis, Atopic / pathology; Gene Expression Regulation / drug effects; Humans; Mitogen-Activated Protein Kinases / genetics; Mitogen-Activated Protein Kinases / metabolism; Oxidation-Reduction; Oxidative Stress; Ozone / metabolism; Ozone / toxicity; Particulate Matter / toxicity; Psoriasis / chemically induced; Psoriasis / genetics; Psoriasis / metabolism; Psoriasis / pathology; Reactive Oxygen Species / agonists; Reactive Oxygen Species / metabolism; Signal Transduction; Skin / drug effects; Skin / metabolism; Skin / pathology; Skin Aging / drug effects; Skin Aging / genetics; Skin Aging / pathology; Tobacco Smoke Pollution / adverse effects; Transcription Factors / genetics; Transcription Factors / metabolism
Sources: Web Of Science, ORCID
Added: April 20, 2020
2019 journal article
Involvement of cutaneous SR-B1 in skin lipid homeostasis
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 666, 1–7.
author keywords: Scavenger receptor; Skin; Keratinocytes; Lipids; Ceramides; Cholesterol; Differentiation
MeSH headings : Cell Differentiation / physiology; Cells, Cultured; Filaggrin Proteins; Gene Expression Regulation; Homeostasis; Humans; Keratinocytes / cytology; Lipid Metabolism / genetics; Scavenger Receptors, Class B / genetics; Scavenger Receptors, Class B / physiology; Skin / cytology; Skin / metabolism
Sources: Web Of Science, ORCID
Added: June 17, 2019
2019 journal article
Involvement of the TREK-1 channel in human alveolar cell membrane potential and its regulation by inhibitors of the chloride current
JOURNAL OF CELLULAR PHYSIOLOGY, 234(10), 17704–17713.
author keywords: 9-AC; A549 cells; ANO-6; DCPIB; K plus channels; pneumocytes
MeSH headings : A549 Cells; Alveolar Epithelial Cells / metabolism; Biological Transport / physiology; Cell Line, Tumor; Cell Membrane / metabolism; Cell Size; Chloride Channels / metabolism; Chlorides / metabolism; Humans; Membrane Potentials / physiology; Patch-Clamp Techniques / methods; Potassium Channels, Tandem Pore Domain / metabolism
Sources: Web Of Science, ORCID
Added: July 29, 2019
2019 journal article
Lipid nanostructures for antioxidant delivery: a comparative preformulation study
BEILSTEIN JOURNAL OF NANOTECHNOLOGY, 10, 1789–1801.
author keywords: alpha-tocopherol; cryogenic transmission electron microscopy (cryo-TEM); dermocosmetics; HO-1; nanostructured lipid carriers (NLCs); retinoic acid; skin pollution; solid lipid nanoparticles (SLNs)
Sources: Web Of Science, ORCID
Added: September 16, 2019
2019 journal article
Multiple mechanisms of Rottlerin toxicity in A375 melanoma cells
BIOFACTORS, 45(6), 920–929.
author keywords: apoptosis; ER stress; melanoma; mitochondria; protein synthesis; rottlerin
Sources: Web Of Science, ORCID
Added: August 26, 2019
2019 article
OxInflammation as a Aossible new Player in Rett Syndrome Pathophysiology
Pecorelli, A., Valacchi, G., Cordone, V., & Hayek, J. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S149–S149.
Sources: Web Of Science, ORCID
Added: December 2, 2019
2019 review
Ozonated Oils and Cutaneous Wound Healing
[Review of ]. CURRENT PHARMACEUTICAL DESIGN, 25(20), 2264–2278.
author keywords: Cutaneous wound healing; ROS; peroxidation; topical application; ozonated oil; inflammation
MeSH headings : Humans; Ozone; Phytotherapy; Plant Oils / therapeutic use; Skin; Wound Healing
Sources: Web Of Science, ORCID
Added: October 7, 2019
2019 article
Redox Regulation of Cutaneous Inflammasome Pathway by Ozone Exposure
Ferrara, F., Pecorelli, A., Woodby, B., Pambianchi, E., Messano, N., Therrien, J. P., & Valacchi, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S22–S23.
Sources: Web Of Science, ORCID
Added: December 2, 2019
2019 article
Redox Regulation of Cutaneous Inflammasome Pathway by Ozone Exposure
FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S22–S23.
Source: ORCID
Added: December 3, 2019
2019 article
Redox-Regulation of Antimicrobial Peptides
Woodby, B., Pambianchi, E., Francesca, F., Messano, N., Pecorelli, A., Therrien, J. P., & Valacchii, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S54–S55.
Sources: Web Of Science, ORCID
Added: December 2, 2019
2019 journal article
Skin damage by tropospheric ozone
HAUTARZT, 70(3), 163–168.
author keywords: Air pollution; Skin aging; Skin wrinkling; Oxidative stress; Peroxidation
MeSH headings : Air Pollutants / adverse effects; Air Pollution; Humans; Lipid Peroxidation / drug effects; Nitrogen Dioxide / analysis; Oxidative Stress; Ozone / adverse effects; Ozone / analysis; Particulate Matter / analysis; Public Health; Skin Aging / drug effects; Skin Aging / radiation effects; Ultraviolet Rays / adverse effects
Sources: Web Of Science, ORCID
Added: March 25, 2019
2019 journal article
Trehalose inhibits cell proliferation and amplifies long-term temozolomide- and radiation-induced cytotoxicity in melanoma cells: A role for autophagy and premature senescence
JOURNAL OF CELLULAR PHYSIOLOGY, 234(7), 11708–11721.
author keywords: melanoma cells; trehalose; autophagy; premature senescence; radiosensitization
MeSH headings : Apoptosis / drug effects; Apoptosis / radiation effects; Autophagy / drug effects; Autophagy / radiation effects; Cell Line, Tumor; Cell Proliferation / drug effects; Cell Proliferation / radiation effects; Cellular Senescence / drug effects; Cellular Senescence / radiation effects; Chloroquine / pharmacology; Drug Resistance, Neoplasm / drug effects; Humans; Melanocytes / drug effects; Melanocytes / metabolism; Melanocytes / pathology; Melanocytes / radiation effects; Melanoma / pathology; Melanoma / radiotherapy; Radiation, Ionizing; Sequestosome-1 Protein / metabolism; Temozolomide / pharmacology; Trehalose / pharmacology
Sources: Web Of Science, ORCID
Added: April 22, 2019
2018 article
AtmO(3)spheric skin damage: The oxInflammation phenomena
Valacchi, G., Pecorelli, A., Pambianchi, E., Ferrara, F., & Lila, M. (2018, September). JOURNAL OF INVESTIGATIVE DERMATOLOGY, Vol. 138, pp. B15–B15.
Sources: Web Of Science, ORCID
Added: October 19, 2018
2018 journal article
Circadian clock as possible protective mechanism to pollution induced keratinocytes damage
Mechanisms of Ageing and Development, 172, 13–20.
author keywords: Ozone (O-3); Oxidative stress; Circadian clock; Antioxidant pathway; Skin homeostasis
MeSH headings : ARNTL Transcription Factors / metabolism; Air Pollutants / toxicity; Cell Line; Circadian Clocks; Gene Expression Regulation / drug effects; Humans; Keratinocytes / metabolism; Keratinocytes / pathology; NF-E2-Related Factor 2 / metabolism; Organ Specificity; Ozone / toxicity; Skin / metabolism; Skin / pathology
Sources: Crossref, ORCID
Added: January 25, 2020
2018 journal article
Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain
ChemMedChem, 13(19), 2090–2103.
author keywords: covalent inhibitors; endocannabinoid system; fatty acid amide hydrolase; neuropathic pain; serine hydrolase
MeSH headings : Amidohydrolases / antagonists & inhibitors; Animals; Benzodiazepinones / chemical synthesis; Benzodiazepinones / pharmacology; Benzodiazepinones / therapeutic use; Benzodiazepinones / toxicity; Cell Line, Tumor; Enzyme Inhibitors / chemical synthesis; Enzyme Inhibitors / pharmacology; Enzyme Inhibitors / therapeutic use; Enzyme Inhibitors / toxicity; Humans; Male; Mice; Molecular Docking Simulation; Molecular Structure; NF-kappa B / metabolism; Neuralgia / drug therapy; Oxidative Stress / drug effects; Structure-Activity Relationship
Sources: Crossref, ORCID
Added: January 25, 2020
2018 article
Inflammasome involvement in Rett syndrome subclinical inflammation
Pecorelli, A., Cordone, V., Falone, S., Romani, A., Benedusi, M., Hayek, J., … Valacchi, G. (2018, November 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 128, pp. S108–S109.
Sources: Web Of Science, ORCID
Added: November 19, 2018
2018 journal article
Keratinocytes oxidative damage mechanisms related to airbone particle matter exposure
MECHANISMS OF AGEING AND DEVELOPMENT, 172, 86–95.
author keywords: Air pollution; Particulate matter; Oxidative damage; Inflammation
MeSH headings : Cell Line, Transformed; Humans; Interleukin-1alpha / metabolism; Keratinocytes / metabolism; Keratinocytes / pathology; NF-E2-Related Factor 2 / metabolism; NF-kappa B / metabolism; Oxidation-Reduction / drug effects; Particulate Matter / toxicity
Sources: Web Of Science, ORCID
Added: August 6, 2018
2018 journal article
Lifestyle determinants of healthy ageing in a Mediterranean population: The multinational MEDIS study
Experimental Gerontology, 110, 35–41.
author keywords: Healthy ageing; Longevity; Elderly; Health policy; Mediterranean
MeSH headings : Aged; Aged, 80 and over; Cardiovascular Diseases / epidemiology; Diet, Mediterranean; Exercise; Feeding Behavior; Female; Healthy Aging; Humans; Logistic Models; Longevity; Male; Mediterranean Region / epidemiology; Risk Factors; Smoking / epidemiology
Sources: Crossref, ORCID
Added: January 25, 2020
2018 journal article
Low-grade systemic inflammation is associated with functional disability in elderly people affected by dementia
GeroScience, 40(1), 61–69.
author keywords: Inflammation; Dementia; Alzheimer's disease; Mixed dementia; Functional abilities
MeSH headings : Activities of Daily Living; Aged; Aged, 80 and over; Aging / physiology; Alzheimer Disease / etiology; Alzheimer Disease / physiopathology; Analysis of Variance; C-Reactive Protein / metabolism; Case-Control Studies; Cognitive Dysfunction / etiology; Cognitive Dysfunction / physiopathology; Dementia / complications; Dementia / diagnosis; Disability Evaluation; Disease Progression; Female; Geriatric Assessment / methods; Homocysteine / metabolism; Humans; Inflammation / complications; Inflammation / diagnosis; Italy; Male; Reference Values; Retrospective Studies
Sources: Crossref, ORCID
Added: January 25, 2020
2018 journal article
Mediterranean diet and depression among older individuals: The multinational MEDIS study
Experimental Gerontology, 110, 67–72.
author keywords: Mediterranean diet; Tea; Depression; Older adults
MeSH headings : Aged; Aged, 80 and over; Cross-Sectional Studies; Depression / epidemiology; Diet, Mediterranean; Female; Geriatric Assessment; Humans; Life Style; Logistic Models; Male; Mediterranean Region / epidemiology; Psychiatric Status Rating Scales; Risk Factors; Self Report; Tea
Sources: Crossref, ORCID
Added: January 25, 2020
2018 journal article
Modulation of cutaneous scavenger receptor B1 levels by exogenous stressors impairs “in vitro” wound closure
Mechanisms of Ageing and Development, 172, 78–85.
author keywords: Skin; Oxidative stress; Pollution; RHE; Wound healing; Particulate matter; Cigarette smoke; Ozone
MeSH headings : Cell Line, Transformed; Epidermis / metabolism; Epidermis / pathology; Gene Expression Regulation; Humans; Keratinocytes / metabolism; Keratinocytes / pathology; Scavenger Receptors, Class B / biosynthesis; Tobacco Smoke Pollution / adverse effects; Wound Healing
Sources: Crossref, ORCID
Added: January 25, 2020
2018 journal article
Non-conventional rottlerin anticancer properties
Archives of Biochemistry and Biophysics, 645, 50–53.
MeSH headings : Acetophenones / pharmacology; Acetophenones / therapeutic use; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Benzopyrans / pharmacology; Benzopyrans / therapeutic use; Breast Neoplasms / drug therapy; Humans; Melanoma / drug therapy
Sources: Crossref, ORCID
Added: January 25, 2020
2018 journal article
OXINFLAMMATION IN RETT SYNDROME
Pathophysiology, 25(3), 189.
Sources: Crossref, ORCID
Added: January 25, 2020
2018 review
OxInflammation: From Subclinical Condition to Pathological Biomarker
[Review of ]. FRONTIERS IN PHYSIOLOGY, 9.
author keywords: biomarkers; neurological disorders; oxidative stress; inflammation mediators; NF kappa B
Sources: Web Of Science, ORCID
Added: August 6, 2018
2018 journal article
Role of Nrf2 in preventing oxidative stress induced chloride current alteration in human lung cells
Journal of Cellular Physiology, 233(8), 6018–6027.
author keywords: catalase; chloride current; ozone; patch clamp; redox imbalance; respiratory tract
MeSH headings : A549 Cells; Antioxidants / metabolism; Catalase / metabolism; Cell Line, Tumor; Cell Survival / drug effects; Cell Survival / physiology; Chloride Channels / metabolism; Chlorides / metabolism; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Gene Expression Regulation / drug effects; Gene Expression Regulation / physiology; Humans; Hydrogen Peroxide / pharmacology; Lung / drug effects; Lung / metabolism; NF-E2-Related Factor 2 / metabolism; Oxidative Stress / drug effects; Oxidative Stress / physiology; Ozone / pharmacology
Sources: Crossref, ORCID
Added: January 25, 2020
2018 journal article
SR-B1 involvement in keratinocytes in vitro wound closure
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 658, 1–6.
author keywords: Wound healing; Skin; Proliferation; Migration
MeSH headings : Cell Line, Transformed; Cell Movement / physiology; Cell Proliferation / physiology; Cyclin D1 / metabolism; Gene Knockout Techniques; Humans; Keratinocytes / cytology; Keratinocytes / physiology; Matrix Metalloproteinase 9 / metabolism; NF-kappa B p50 Subunit / metabolism; Scavenger Receptors, Class B / genetics; Scavenger Receptors, Class B / physiology; Skin / metabolism; Wound Healing / physiology
Sources: Web Of Science, ORCID
Added: November 26, 2018
2018 article
Scavenger receptor B1 as a possible new player in cutaneous tissue proliferation and differentiation
Valacchi, G., Muresan, X., Belmonte, G., Pecorelli, A., & Gruber, F. (2018, September). JOURNAL OF INVESTIGATIVE DERMATOLOGY, Vol. 138, pp. B25–B25.
Sources: Web Of Science, ORCID
Added: October 19, 2018
2018 journal article
Tropospheric ozone affects SRB1 levels via oxidative post-translational modifications in lung cells
FREE RADICAL BIOLOGY AND MEDICINE, 126, 287–295.
MeSH headings : A549 Cells; Aldehydes / metabolism; Alveolar Epithelial Cells / drug effects; Alveolar Epithelial Cells / metabolism; Antioxidants / pharmacology; Biological Transport / drug effects; Catalase / genetics; Catalase / metabolism; Cell Survival / drug effects; Humans; Hydrogen Peroxide / metabolism; Lung / drug effects; Lung / metabolism; Lung / pathology; Oxidation-Reduction / drug effects; Oxidative Stress / drug effects; Ozone / pharmacology; Protein Processing, Post-Translational / drug effects; Scavenger Receptors, Class B / genetics; Scavenger Receptors, Class B / metabolism; Vitamin E / metabolism
Sources: Web Of Science, ORCID
Added: October 16, 2018
2017 review
4-hydroxynonenal protein adducts: Key mediator in Rett syndrome oxinflammation
[Review of ]. FREE RADICAL BIOLOGY AND MEDICINE, 111, 270–280.
author keywords: Inflammation; Isoprostanes; Oxidative stress; Rare disease; Orphan disease; CDKL5; FOXG1; MecP2
MeSH headings : Aldehydes / metabolism; Brain / metabolism; Brain / pathology; Feedback, Physiological; Forkhead Transcription Factors / genetics; Forkhead Transcription Factors / metabolism; Humans; Inflammation; Isoprostanes / metabolism; Lipid Peroxidation / genetics; Methyl-CpG-Binding Protein 2 / genetics; Methyl-CpG-Binding Protein 2 / metabolism; Mutation; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / metabolism; Oxidative Stress; Proteasome Endopeptidase Complex / metabolism; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases / genetics; Protein Serine-Threonine Kinases / metabolism; Rett Syndrome / genetics; Rett Syndrome / metabolism; Rett Syndrome / pathology
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
First dual AK/GSK-3 beta inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 138, 438–457.
author keywords: Antioxidant agents; Glycogen synthase kinase 3 beta (GSK-3 beta); Adenosine kinase (AK); Dual inhibitors; Molecular docking
MeSH headings : Adenosine Kinase / antagonists & inhibitors; Adenosine Kinase / metabolism; Antioxidants / chemical synthesis; Antioxidants / chemistry; Antioxidants / pharmacology; Cell Line, Tumor; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3 beta / antagonists & inhibitors; Glycogen Synthase Kinase 3 beta / metabolism; Humans; Hydrogen Peroxide / antagonists & inhibitors; Hydrogen Peroxide / pharmacology; Molecular Structure; Neuroblastoma / metabolism; Neuroblastoma / pathology; Neuroprotective Agents / chemical synthesis; Neuroprotective Agents / chemistry; Neuroprotective Agents / pharmacology; Oxidative Stress / drug effects; Protein Kinase Inhibitors / chemical synthesis; Protein Kinase Inhibitors / chemistry; Protein Kinase Inhibitors / pharmacology; Reactive Oxygen Species / metabolism; Structure-Activity Relationship
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Is car use related with successful aging of older adults? Results from the multinational Mediterranean islands study
Annals of Epidemiology, 27(3), 225–229.
author keywords: Successful aging; Car use; Driving; Mediterranean islands; Older adults
MeSH headings : Aged; Aged, 80 and over; Aging / physiology; Aging / psychology; Automobile Driving / psychology; Automobile Driving / statistics & numerical data; Cross-Sectional Studies; Female; Greece; Humans; Male; Mediterranean Islands; Quality of Life / psychology; Rural Population / statistics & numerical data
Sources: Crossref, ORCID
Added: January 25, 2020
2017 journal article
Mediterranean lifestyle and cardiovascular disease prevention
Cardiovascular Diagnosis and Therapy, 7, S39–47.
Source: NC State University Libraries
Added: August 6, 2018
2017 journal article
Modulation of Chloride Currents in Human Lung Epithelial Cells Exposed to Exogenous Oxidative Stress
JOURNAL OF CELLULAR PHYSIOLOGY, 232(7), 1817–1825.
MeSH headings : A549 Cells; Chloride Channels / metabolism; Electrophysiological Phenomena / drug effects; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Humans; Lung / pathology; Oxidative Stress / drug effects; Ozone / pharmacology; Patch-Clamp Techniques; Protective Agents / pharmacology; Vitamin E / pharmacology
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Monoolein aqueous dispersions as a delivery system for quercetin
Biomedical Microdevices, 19(2).
author keywords: Quercetin; Monoolein aqueous dispersions (MAD); Monoolein; Antioxidant activity
MeSH headings : Antioxidants / chemistry; Antioxidants / toxicity; Cell Line; Drug Carriers / chemistry; Glycerides / chemistry; Humans; Kinetics; Quercetin / chemistry; Quercetin / toxicity; Water / chemistry
Sources: Crossref, ORCID
Added: January 25, 2020
2017 journal article
Nanostructured lipid carriers (NLC) for the delivery of natural molecules with antimicrobial activity: production, characterisation and in vitro studies
Journal of Microencapsulation, 34(1), 63–72.
author keywords: Nanoparticles; nanotechnology; formulation; nanostructured lipid carriers
MeSH headings : Anti-Infective Agents / administration & dosage; Anti-Infective Agents / pharmacology; Bacteria / drug effects; Bacterial Infections / drug therapy; Cell Line; Cyanobacteria / drug effects; Drug Carriers / chemistry; Fungi / drug effects; Humans; Lipids / chemistry; Mycoses / drug therapy; Nanostructures / chemistry; Nanostructures / ultrastructure
Sources: Crossref, ORCID
Added: January 25, 2020
2017 journal article
Nanostructured lipid systems modified with waste material of propolis for wound healing: Design, in vitro and in vivo evaluation
Colloids and Surfaces B: Biointerfaces, 158, 441–452.
author keywords: Nanotechnology; Materials science; Formulation; Propolis by-product; Nanoparticles; Nanostructured lipid carriers; Propolis byproduct
MeSH headings : Drug Delivery Systems / methods; Lipids / chemistry; Nanoparticles / chemistry; Nanostructures / chemistry; Nanotechnology / methods; Propolis / chemistry; Wound Healing / physiology
Sources: Crossref, ORCID
Added: January 25, 2020
2017 journal article
Novel Artificial Tears Containing Cross-Linked Hyaluronic Acid: An In Vitro Re-Epithelialization Study
MOLECULES, 22(12).
author keywords: anti-inflammatory; artificial tears; corneal epithelium; cyclin D1; dry eye syndrome; HA; HA-CL; IL-8; re-epithelialization
MeSH headings : Analysis of Variance; Biomarkers; Cell Line; Cell Survival; Cyclin D1 / metabolism; Drug Stability; Dry Eye Syndromes; Epithelium, Corneal / drug effects; Humans; Hyaluronic Acid / analysis; Hyaluronic Acid / chemistry; Hydrogen-Ion Concentration; Lubricant Eye Drops / analysis; Lubricant Eye Drops / chemical synthesis; Lubricant Eye Drops / chemistry; Lubricant Eye Drops / pharmacology; Re-Epithelialization / drug effects; Viscosity; Wound Healing / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Paraoxonase, arylesterase and lactonase activities of paraoxonase-1 (PON1) in obese and severely obese women
Scandinavian Journal of Clinical and Laboratory Investigation, 78(1-2), 18–24.
author keywords: Arylesterase; body mass index; markers of oxidative stress; obesity; paraoxonase-1
MeSH headings : Anthropometry; Aryldialkylphosphatase / blood; Body Mass Index; Carboxylic Ester Hydrolases / blood; Female; Humans; Middle Aged; Obesity / blood; Obesity / enzymology; Regression Analysis
Sources: Crossref, ORCID
Added: January 25, 2020
2017 journal article
Potassium Ascorbate with Ribose: Promising Therapeutic Approach for Melanoma Treatment
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2017.
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Ascorbic Acid / chemistry; Cell Line, Tumor; Cell Proliferation / drug effects; Cell Survival / drug effects; Connexin 43 / genetics; Connexin 43 / metabolism; Humans; Melanoma / drug therapy; Melanoma / pathology; Microscopy, Electron, Scanning; Potassium / chemistry; Ribose / chemistry; Spheroids, Cellular / drug effects; Spheroids, Cellular / ultrastructure
Sources: Web Of Science, ORCID
Added: August 6, 2018
2017 journal article
Protective Effects of Topical Vitamin C Compound Mixtures against Ozone-Induced Damage in Human Skin
Journal of Investigative Dermatology, 137(6), 1373–1375.
MeSH headings : Administration, Topical; Antioxidants / therapeutic use; Ascorbic Acid / therapeutic use; Biopsy, Needle; Dermatitis / drug therapy; Dermatitis / etiology; Dermatitis / pathology; Environmental Exposure / adverse effects; Female; Humans; Immunohistochemistry; Male; Oxidative Stress / drug effects; Ozone / adverse effects; Reference Values; Risk Assessment; Treatment Outcome
Sources: Crossref, ORCID
Added: January 25, 2020
2017 journal article
Resveratrol: from diet to topical usage
Food & Function, 8(11), 3879–3892.
MeSH headings : Animals; Cardiovascular Diseases / prevention & control; Cosmetics / analysis; Humans; Resveratrol; Skin / drug effects; Skin / metabolism; Stilbenes / metabolism; Stilbenes / pharmacology
Sources: Crossref, ORCID
Added: January 25, 2020
2017 journal article
Retention of mitochondria in mature human red blood cells as the result of autophagy impairment in Rett syndrome
Scientific Reports, 7.
MeSH headings : Animals; Autophagosomes / pathology; Autophagy / genetics; Cells, Cultured; Cerebellum / pathology; Disease Models, Animal; Erythrocytes / cytology; Erythrocytes / metabolism; Erythrocytes / ultrastructure; Female; Fibroblasts; Healthy Volunteers; Humans; Male; Methyl-CpG-Binding Protein 2 / genetics; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mutation; Primary Cell Culture; Protein Aggregates / genetics; Rett Syndrome / blood; Rett Syndrome / genetics; Rett Syndrome / pathology; Sequestosome-1 Protein / metabolism
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2017 article
Serum from patients affected by Alzheimer disease shows a paraoxonase-dependent pro-apoptotic effect on endothelial cells
Crivellari, I., Cervellati, C., Dalla Sega, F. V., Valacchi, G., Trentini, A., Passaro, A., … Rizzo, P. (2017, July). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 108, pp. S93–S93.
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 journal article
Abnormal N-glycosylation pattern for brain nucleotide pyrophosphatase-5 (NPP-5) in Mecp2-mutant murine models of Rett syndrome
Neuroscience Research, 105, 28–34.
author keywords: Protein glycosylation; Neurological disorders; Nucleotide pyrophosphatase; Mecp2
MeSH headings : Animals; Brain / metabolism; Glycosylation; Membrane Glycoproteins / metabolism; Methyl-CpG-Binding Protein 2 / genetics; Methyl-CpG-Binding Protein 2 / metabolism; Mice, Mutant Strains; Pyrophosphatases / metabolism; Rett Syndrome / metabolism
Sources: Crossref, ORCID
Added: September 4, 2020
2016 journal article
Association between siesta (daytime sleep), dietary patterns and the presence of metabolic syndrome in elderly living in Mediterranean area (MEDIS study): The moderating effect of gender
The Journal of Nutrition, Health & Aging, 21(10), 1118–1124.
author keywords: Metabolic syndrome; sleep; elderly; diet; lifestyle; MEDIS; siesta; mediterranean-type diet
MeSH headings : Aged; Aged, 80 and over; Cross-Sectional Studies; Energy Intake / physiology; Feeding Behavior / physiology; Female; Gender Identity; Humans; Life Style; Male; Mediterranean Islands; Metabolic Syndrome / epidemiology; Metabolic Syndrome / etiology; Prevalence; Sleep / physiology
Sources: Crossref, ORCID
Added: January 21, 2021
2016 journal article
Cytokines profile and peripheral blood mononuclear cells morphology in Rett and autistic patients
Cytokine, 77, 180–188.
author keywords: Rett syndrome; Autism spectrum disorders; Cytokine; Chemokine; Immune system; Peripheral blood mononuclear cells; Mitochondria
MeSH headings : Adolescent; Adult; Autistic Disorder / blood; Autistic Disorder / genetics; Child; Child, Preschool; Cytokines / blood; Cytokines / genetics; Gene Expression Profiling; Humans; Immunoenzyme Techniques / methods; Interleukin-13 / blood; Interleukin-13 / genetics; Interleukin-15 / blood; Interleukin-15 / genetics; Interleukin-1beta / blood; Interleukin-1beta / genetics; Interleukin-8 / blood; Interleukin-8 / genetics; Interleukin-9 / blood; Interleukin-9 / genetics; Leukocytes, Mononuclear / metabolism; Leukocytes, Mononuclear / ultrastructure; Microscopy, Electron, Transmission; Rett Syndrome / blood; Rett Syndrome / genetics; Reverse Transcriptase Polymerase Chain Reaction; Vascular Endothelial Growth Factor A / blood; Vascular Endothelial Growth Factor A / genetics; Young Adult
Sources: Crossref, ORCID
Added: September 4, 2020
2016 journal article
Decreased arylesterase activity of paraoxonase-1 (PON-1) might be a common denominator of neuroinflammatory and neurodegenerative diseases
The International Journal of Biochemistry & Cell Biology, 81, 356–363.
author keywords: Paraoxonase-1; Arylesterase activity; Multiple sclerosis; Alzheimer's disease; Vascular dementia
MeSH headings : Aged; Aryldialkylphosphatase / blood; Aryldialkylphosphatase / metabolism; Biomarkers / blood; Biomarkers / metabolism; Carboxylic Ester Hydrolases / blood; Carboxylic Ester Hydrolases / metabolism; Dementia / blood; Dementia / diagnosis; Dementia / enzymology; Female; Humans; Male; Multiple Sclerosis / blood; Multiple Sclerosis / diagnosis; Multiple Sclerosis / enzymology; Multiple Sclerosis / physiopathology; Neurodegenerative Diseases / blood; Neurodegenerative Diseases / diagnosis; Neurodegenerative Diseases / enzymology; Neurodegenerative Diseases / metabolism; Risk Factors
Sources: Crossref, ORCID
Added: September 4, 2020
2016 journal article
Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress
ACS Chemical Neuroscience, 7(6), 737–748.
author keywords: TRPV1 ligands; capsaicin; antioxidant; oxidative stress; neuroprotective; antinociceptive
MeSH headings : Analgesics / pharmacology; Animals; CHO Cells; Capsaicin / pharmacology; Cricetulus / metabolism; Male; Models, Molecular; Oxidative Stress / drug effects; Rats, Wistar; TRPV Cation Channels / agonists; TRPV Cation Channels / metabolism; Thiophenes / chemical synthesis; Thiophenes / chemistry; Thiophenes / pharmacology
Sources: Crossref, ORCID
Added: January 21, 2021
2016 journal article
Inhibitions of mTORC1 and 4EBP-1 are key events orchestrated by Rottlerin in SK-Mel-28 cell killing
Cancer Letters, 380(1), 106–113.
author keywords: Rottlerin; AMPK; mTOR; 4EBP-1; Autophagy; Protein synthesis
MeSH headings : Acetophenones / pharmacology; Adaptor Proteins, Signal Transducing / antagonists & inhibitors; Adaptor Proteins, Signal Transducing / metabolism; Antineoplastic Agents / pharmacology; Antineoplastic Agents / toxicity; Autophagy / drug effects; Benzopyrans / pharmacology; Cell Cycle Proteins; Cell Line; Dose-Response Relationship, Drug; Humans; Mechanistic Target of Rapamycin Complex 1; Melanoma / drug therapy; Melanoma / enzymology; Melanoma / pathology; Multiprotein Complexes / antagonists & inhibitors; Multiprotein Complexes / metabolism; Phosphoproteins / antagonists & inhibitors; Phosphoproteins / metabolism; Protein Biosynthesis / drug effects; Protein Kinase Inhibitors / pharmacology; Protein Kinase Inhibitors / toxicity; Protein Synthesis Inhibitors / pharmacology; Protein Synthesis Inhibitors / toxicity; Signal Transduction / drug effects; Skin Neoplasms / drug therapy; Skin Neoplasms / enzymology; Skin Neoplasms / pathology; TOR Serine-Threonine Kinases / antagonists & inhibitors; TOR Serine-Threonine Kinases / metabolism; Time Factors
Sources: Crossref, ORCID
Added: September 4, 2020
2016 journal article
OxInflammation in Rett syndrome
The International Journal of Biochemistry & Cell Biology, 81, 246–253.
author keywords: Rett syndrome; MECP2; Oxidative stress; Inflammation; Cytokines
MeSH headings : Humans; Inflammation / physiopathology; Methyl-CpG-Binding Protein 2 / genetics; Methyl-CpG-Binding Protein 2 / metabolism; Oxidative Stress; Rett Syndrome / physiopathology
Sources: Crossref, ORCID
Added: September 4, 2020
2016 journal article
Ozone mediators effect on “in vitro” scratch wound closure
Free Radical Research, 50(9), 1022–1031.
author keywords: Cutaneous tissues; wound healing; HNE; H2O2; oxidative stress
MeSH headings : Humans; Hydrogen Peroxide / metabolism; Oxidative Stress; Skin / drug effects; Wound Healing / physiology
Sources: Crossref, ORCID
Added: September 4, 2020
2016 journal article
Ozone-induced damage in 3D-Skin Model is prevented by topical vitamin C and vitamin E compound mixtures application
Journal of Dermatological Science, 82(3), 209–212.
MeSH headings : Administration, Cutaneous; Antioxidants / administration & dosage; Antioxidants / pharmacology; Ascorbic Acid / administration & dosage; Ascorbic Acid / pharmacology; Drug Combinations; Environmental Exposure / adverse effects; Epidermis / drug effects; Epidermis / pathology; Humans; Models, Anatomic; Oxidants, Photochemical / toxicity; Ozone / toxicity; Sebum / drug effects; Vitamin E / administration & dosage; Vitamin E / pharmacology
Sources: Crossref, ORCID
Added: September 4, 2020
2016 journal article
Proteomic analysis of 4-hydroxynonenal and nitrotyrosine modified proteins in RTT fibroblasts
The International Journal of Biochemistry & Cell Biology, 81, 236–245.
author keywords: Oxidative stress; 4-hydroxynonenal; Nitric monoxide; Nitrotyrosine; Inducible nitric oxide synthase; Post-translational modification
MeSH headings : Aldehydes / chemistry; Aldehydes / metabolism; Blotting, Western; Case-Control Studies; Cells, Cultured; Female; Fibroblasts / chemistry; Fibroblasts / metabolism; Fibroblasts / pathology; Humans; Proteins / chemistry; Proteins / genetics; Proteome; Proteomics; Real-Time Polymerase Chain Reaction; Rett Syndrome / genetics; Rett Syndrome / physiopathology; Tyrosine / analogs & derivatives; Tyrosine / chemistry; Tyrosine / metabolism
Sources: Crossref, ORCID
Added: September 4, 2020
2016 journal article
Redox regulation of inflammatory processes
The International Journal of Biochemistry & Cell Biology, 81, 234–235.
Sources: Crossref, ORCID
Added: September 4, 2020
2016 journal article
Skeletal muscle mass and body fat in relation to successful ageing of older adults: The multi-national MEDIS study
Archives of Gerontology and Geriatrics, 66, 95–101.
author keywords: Successful ageing; Appendicular skeletal muscle mass; Body fat; Energy balance; Older adults
MeSH headings : Adipose Tissue; Aged; Aged, 80 and over; Aging; Body Composition; Body Mass Index; Cross-Sectional Studies; Energy Intake; Energy Metabolism; Feeding Behavior; Female; Greece / epidemiology; Humans; Male; Mediterranean Region / epidemiology; Muscle, Skeletal; Quality of Life; Sarcopenia / epidemiology
Sources: Crossref, ORCID
Added: September 4, 2020
2016 journal article
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity
European Journal of Medicinal Chemistry, 109, 99–106.
author keywords: COX-2 inhibitors; 1,5-diarylpyrrole derivatives; Anti-inflammatory agents; Antinociceptive agents; Antiproliferative activity; Molecular modelling
MeSH headings : Adult; Analgesics / chemical synthesis; Analgesics / chemistry; Analgesics / therapeutic use; Animals; Anti-Inflammatory Agents, Non-Steroidal / chemical synthesis; Anti-Inflammatory Agents, Non-Steroidal / chemistry; Anti-Inflammatory Agents, Non-Steroidal / therapeutic use; Antineoplastic Agents / chemical synthesis; Antineoplastic Agents / chemistry; Antineoplastic Agents / therapeutic use; Cell Line; Cell Proliferation / drug effects; Cyclooxygenase 2 / metabolism; Cyclooxygenase 2 Inhibitors / chemical synthesis; Cyclooxygenase 2 Inhibitors / chemistry; Cyclooxygenase 2 Inhibitors / therapeutic use; Edema / drug therapy; Halogenation; Humans; Hyperalgesia / drug therapy; Models, Molecular; Pyrroles / chemical synthesis; Pyrroles / chemistry; Pyrroles / therapeutic use; Rats; Skin / drug effects; Skin / pathology; Skin Neoplasms / drug therapy; Skin Neoplasms / pathology
Sources: Crossref, ORCID
Added: January 21, 2021
2016 journal article
Targeted lipidomics distinguishes patient subgroups in mild cognitive impairment (MCI) and late onset Alzheimer's disease (LOAD)
BBA Clinical, 5, 25–28.
author keywords: MCI; AD; Plasmalogens; DAG; Patient stratification
Sources: Crossref, ORCID
Added: September 4, 2020
2015 journal article
Chondroprotective effect of three different classes of anti-inflammatory agents on human osteoarthritic chondrocytes exposed to IL-1β
International Immunopharmacology, 28(1), 794–801.
author keywords: Chondrocyte; Osteoarthritis; Nitric oxide-selective cyclooxigenase-2 inhibitors; Cyclooxigenase inhibitor nitric oxide donors; Naproxen; VA694
MeSH headings : Aged; Anti-Inflammatory Agents, Non-Steroidal / administration & dosage; Anti-Inflammatory Agents, Non-Steroidal / chemistry; Anti-Inflammatory Agents, Non-Steroidal / pharmacology; Cell Culture Techniques; Cell Survival / drug effects; Cells, Cultured; Chondrocytes / drug effects; Chondrocytes / immunology; Cyclooxygenase 2 / genetics; Dinoprostone / analysis; Dinoprostone / metabolism; Dose-Response Relationship, Drug; Gene Expression / drug effects; Humans; Interleukin-1beta / pharmacology; Matrix Metalloproteinases / genetics; Middle Aged; Molecular Structure; NF-kappa B / immunology; Naproxen / analogs & derivatives; Naproxen / chemistry; Naproxen / pharmacology; Nitrates / chemistry; Nitrates / pharmacology; Osteoarthritis, Hip / immunology; Pyrroles / chemistry; Pyrroles / pharmacology
Sources: Crossref, ORCID
Added: September 4, 2020
2015 journal article
Correction: Wound healing properties of hyaluronan derivatives bearing ferulate residues
Journal of Materials Chemistry B, 3(36), 7307–7307.
Sources: Crossref, ORCID
Added: September 4, 2020
2015 journal article
Impaired enzymatic defensive activity, mitochondrial dysfunction and proteasome activation are involved in RTT cell oxidative damage
Biochimica Et Biophysica Acta (BBA) - Molecular Basis of Disease, 1852(10), 2066–2074.
author keywords: Oxidative stress; NADPH oxidase; Glutathione peroxidase; Superoxide dismutase thioredoxin-reductases; 4HNE
Sources: Crossref, ORCID
Added: September 4, 2020
2015 journal article
NADPH oxidase activation and 4-hydroxy-2-nonenal/aquaporin-4 adducts as possible new players in oxidative neuronal damage presents in drug-resistant epilepsy
Biochimica Et Biophysica Acta (BBA) - Molecular Basis of Disease, 1852(3), 507–519.
author keywords: 4-Hydroxy-2-nonenal; Matrix metalloproteinase; NADPH oxidase; Aquaporin-4; Drug-resistant epilepsy
MeSH headings : Adolescent; Adult; Aldehydes / metabolism; Aquaporin 4 / metabolism; Astrocytes / metabolism; Astrocytes / pathology; Child, Preschool; Drug Resistance; Enzyme Activation; Epilepsy / mortality; Epilepsy / pathology; Female; Hippocampus / metabolism; Hippocampus / pathology; Humans; Lipid Peroxidation; Male; Membrane Glycoproteins / metabolism; NADPH Oxidase 2; NADPH Oxidases / metabolism; Neurodegenerative Diseases / metabolism; Neurodegenerative Diseases / pathology; Neurons / metabolism; Neurons / pathology; Superoxides / metabolism; Water-Electrolyte Balance
Sources: Crossref, ORCID
Added: September 4, 2020
2015 journal article
Phosphorylation-independent mTORC1 inhibition by the autophagy inducer Rottlerin
Cancer Letters, 360(1), 17–27.
author keywords: Rottlerin; AMPK; mTOR; Raptor; Autophagy
MeSH headings : AMP-Activated Protein Kinases / metabolism; Acetophenones / pharmacology; Adenocarcinoma / enzymology; Adenocarcinoma / genetics; Adenocarcinoma / pathology; Antineoplastic Agents / pharmacology; Autophagy / drug effects; Benzopyrans / pharmacology; Breast Neoplasms / enzymology; Breast Neoplasms / genetics; Breast Neoplasms / pathology; Female; Humans; MCF-7 Cells; Mechanistic Target of Rapamycin Complex 1; Multiprotein Complexes / antagonists & inhibitors; Multiprotein Complexes / metabolism; Phosphorylation; Protein Kinase C-delta / metabolism; Protein Kinase Inhibitors / pharmacology; RNA Interference; Signal Transduction / drug effects; TOR Serine-Threonine Kinases / antagonists & inhibitors; TOR Serine-Threonine Kinases / genetics; TOR Serine-Threonine Kinases / metabolism; Time Factors; Transfection
Sources: Crossref, ORCID
Added: September 4, 2020
2015 journal article
Protective Effect of Palmitoylethanolamide in a Rat Model of Cystitis
Journal of Urology, 193(4), 1401–1408.
author keywords: urinary bladder; cystitis; interstitial; palmidrol; cyclophosphamide; receptors; cannabinoid
MeSH headings : Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal / therapeutic use; Cyclophosphamide; Cystitis / chemically induced; Cystitis / prevention & control; Disease Models, Animal; Ethanolamines / therapeutic use; Female; Palmitic Acids / therapeutic use; Rats; Rats, Wistar
Sources: Crossref, ORCID
Added: September 4, 2020
2015 journal article
The Air Quality Health Index and Emergency Department Visits for Urticaria in Windsor, Canada
Journal of Toxicology and Environmental Health, Part A, 78(8), 524–533.
MeSH headings : Adolescent; Adult; Age Factors; Aged; Air Pollutants / analysis; Air Pollutants / toxicity; Air Pollution / adverse effects; Child; Emergency Service, Hospital; Environmental Exposure / adverse effects; Environmental Illness / chemically induced; Environmental Illness / epidemiology; Environmental Illness / therapy; Environmental Monitoring; Female; Hospitals, Urban; Humans; Infant; Male; Models, Biological; Nitrogen Dioxide / analysis; Nitrogen Dioxide / toxicity; Ontario / epidemiology; Oxidants, Photochemical / analysis; Oxidants, Photochemical / toxicity; Ozone / analysis; Ozone / toxicity; Particulate Matter / analysis; Particulate Matter / toxicity; Risk; Sex Characteristics; Urban Health; Urticaria / chemically induced; Urticaria / epidemiology; Urticaria / therapy
Sources: Crossref, ORCID
Added: September 4, 2020
2015 journal article
The effects of three different classes of anti-inflammatory agents on in vitro human osteoarthritic chondrocytes exposed to IL-1β
Osteoarthritis and Cartilage, 23, A159–A160.
Sources: Crossref, ORCID
Added: September 4, 2020
2015 journal article
Wound healing properties of hyaluronan derivatives bearing ferulate residues
Journal of Materials Chemistry B, 3(35), 7037–7045.
Sources: Crossref, ORCID
Added: September 4, 2020
2014 journal article
Altered erythrocyte membrane fatty acid profile in typical Rett syndrome: Effects of omega-3 polyunsaturated fatty acid supplementation
Prostaglandins, Leukotrienes and Essential Fatty Acids, 91(5), 183–193.
author keywords: Omega-3 polyunsaturated fatty acids; Erythrocyte membrane; Inflammation; Isoprostanes; Rett syndrome
MeSH headings : Adolescent; Adult; Animals; Biomarkers / blood; Child; Child, Preschool; Dietary Supplements; Docosahexaenoic Acids / administration & dosage; Docosahexaenoic Acids / metabolism; Eicosapentaenoic Acid / administration & dosage; Eicosapentaenoic Acid / metabolism; Erythrocyte Membrane / drug effects; Erythrocyte Membrane / metabolism; Erythrocyte Membrane / pathology; Fatty Acids, Omega-3 / administration & dosage; Fatty Acids, Omega-3 / metabolism; Female; Humans; Inflammation / metabolism; Inflammation / pathology; Isoprostanes / blood; Lipids / blood; Rett Syndrome / diet therapy; Rett Syndrome / metabolism; Rett Syndrome / pathology
Sources: Crossref, ORCID
Added: September 11, 2020
2014 journal article
Comparative effects between electronic and cigarette smoke in human keratinocytes and epithelial lung cells
Toxicology in Vitro, 28(5), 999–1005.