Works (208)

Updated: February 15th, 2024 05:04

2024 journal article

A proteomic approach to investigate the role of the MECP2 gene mutation in Rett syndrome redox regulatory pathways

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 752.

By: A. Pasqui*, V. Cicaloni*, L. Tinti*, A. Guiotto n, C. Tinti*, A. Mori*, M. Bruttini*, J. Hayek* ...

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: Rett syndrome; MECP2 mutations; Precision medicine; Proteomics; Oxidative stress
Sources: Web Of Science, ORCID
Added: February 12, 2024

2024 journal article

Ethosomes for Curcumin and Piperine Cutaneous Delivery to Prevent Environmental-Stressor-Induced Skin Damage

ANTIOXIDANTS, 13(1).

By: F. Ferrara*, A. Bondi*, W. Pula*, C. Contado*, A. Baldisserotto*, S. Manfredini*, P. Boldrini*, M. Sguizzato* ...

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: ethosomes (ETs); curcumin (CUR); piperin (PIP); skin; environmental stress
Sources: Web Of Science, ORCID
Added: February 12, 2024

2024 journal article

Nutlin-3 Loaded Ethosomes and Transethosomes to Prevent UV-Associated Skin Damage

LIFE-BASEL, 14(1).

By: E. Esposito*, F. Ferrara*, M. Drechsler*, O. Bortolini*, D. Ragno*, S. Toldo*, A. Bondi*, A. Pecorelli* ...

co-author countries: Germany 🇩🇪 Italy 🇮🇹 Saudi Arabia 🇸🇦 United States of America 🇺🇸
author keywords: nutlin-3; ethosomes; transethosomes; skin damage; UV radiations
Sources: Web Of Science, ORCID
Added: February 12, 2024

2024 journal article

Signature of paraoxonases in the altered redox homeostasis in Alzheimer's disease

CHEMICO-BIOLOGICAL INTERACTIONS, 388.

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: Paraoxonase 1; Paraoxonase 2; 4-Hydroxynonenal; Oxidative stress
Sources: Web Of Science, ORCID
Added: February 12, 2024

2024 journal article

Vitamin C compounds mixture prevents skin barrier alterations and inflammatory responses upon real life multi pollutant exposure

EXPERIMENTAL DERMATOLOGY, 33(1).

By: F. Ferrara*, A. Pecorelli*, E. Pambianchi*, S. White*, H. Choudhary*, A. Casoni*, G. Valacchi*

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: 4HNE; COX2; inflammation; pollution; skin barrier
Sources: Web Of Science, ORCID
Added: January 29, 2024

2023 journal article

Astaxanthin supplementation counters exercise-induced decreases in immune-related plasma proteins

FRONTIERS IN NUTRITION, 10.

By: D. Nieman*, J. Woo*, C. Sakaguchi*, A. Omar*, Y. Tang*, K. Davis*, A. Pecorelli n, G. Valacchi n, Q. Zhang*

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: astaxanthin; exercise; proteomics; oxylipins; inflammation; cytokines
Sources: Web Of Science, ORCID
Added: April 17, 2023

2023 journal article

Bilosomes and Biloparticles for the Delivery of Lipophilic Drugs: A Preliminary Study

ANTIOXIDANTS, 12(12).

By: M. Sguizzato, F. Ferrara, N. Baraldo, A. Bondi, A. Guarino, M. Drechsler, G. Valacchi, R. Cortesi

author keywords: bile acids; nanovesicles; nanoparticles; SLN; NLC; drug solubility; nanotechnology; poorly water-soluble drugs; immunofluorescence; inflammasome
Sources: Web Of Science, ORCID
Added: January 16, 2024

2023 review

Blueberry Supplementation and Skin Health

[Review of ]. ANTIOXIDANTS, 12(6).

By: J. Ivarsson n, A. Pecorelli*, M. Lila n & G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: blueberries; skin; inflammation; polyphenol; antioxidant
Sources: Web Of Science, ORCID
Added: June 14, 2023

2023 review

Bone Fracture in Rett Syndrome: Mechanisms and Prevention Strategies

[Review of ]. CHILDREN-BASEL, 10(12).

By: C. Caffarelli*, A. Al Refaie*, C. Mondillo*, M. De Vita*, L. Baldassini*, G. Valacchi n, S. Gonnelli*

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: Rett syndrome; fractures; osteoporosis; calcium; vitamin D; bisphosphonates
Sources: Web Of Science, ORCID
Added: January 8, 2024

2023 article

CADMIUM EXPOSURE AFFECTS THE PROGRESSION OF HUMAN METASTATIC MELANOMA BY INDUCING A DEREGULATION OF ANTIOXIDANT CELL RESPONSE

Casoni, A., Benedusi, M., Cervellati, F., Pecorelli, A., Ferrara, F., Vallese, A., & Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 42–43.

By: A. Casoni*, M. Benedusi*, F. Cervellati*, A. Pecorelli*, F. Ferrara*, A. Vallese*, G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 article

CONSTITUTIVE ACTIVATION OF NLRP3 INFLAMMASOME MACHINERY IN EX-VIVO MODELS OF RETT SYNDROME: FROM PATHOGENETIC ROLE TO NEW POTENTIAL THERAPEUTIC TARGET

Cordone, V., Pecorelli, A., Ferrara, F., Guiotto, A., Hayek, J., Cervellati, C., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 12–12.

By: V. Cordone*, A. Pecorelli*, F. Ferrara*, A. Guiotto*, J. Hayek*, C. Cervellati*, F. Amicarelli*, G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 article

Caffeic acid-loaded lipid nanoparticles as a tool to protect skin against oxidative stress: formulation and evaluation on human skin explants

Sguizzato, M., Ferrara, F., Valacchi, G., Cortesi, R., & Esposito, E. (2023, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 198, pp. S19–S19.

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷
Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 journal article

Comparison of Pollutant Effects on Cutaneous Inflammasomes Activation

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 24(23).

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: oxinflammation; inflammasome; pollutants; skin
Sources: Web Of Science, ORCID
Added: November 24, 2023

2023 article

Deregulated NLRP3 inflammasome response due to a constitutive activation of NF-kappa B p65 pro-inflammatory pathway in lymphomonocytes of Rett syndrome patients

Cordone, V., Vallese, A., Pecorelli, A., Guiotto, A., Ferrara, F., Benedusi, M., … Valacchi, G. (2023, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 198, pp. S21–S22.

By: V. Cordone*, A. Vallese*, A. Pecorelli n, A. Guiotto*, F. Ferrara*, M. Benedusi*, F. Cervellati*, J. Hayek*, G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 journal article

Development of Spray Dried Spirulina Protein-Berry Pomace Polyphenol Particles to Attenuate Pollution-Induced Skin Damage: A Convergent Food-Beauty Approach

ANTIOXIDANTS, 12(7).

By: R. Hoskin n, M. Grace n, A. Guiotto n, A. Pecorelli n, G. Valacchi n & M. Lila n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: sustainability; value-added; repurposing; skin health; cosmeceuticals
Sources: Web Of Science, ORCID
Added: July 17, 2023

2023 article

Editorial: Cell cycle control as a new therapeutic approach for SARS-CoV-2 infection

Rizzo, R., Caccuri, F., Valacchi, G., & Zauli, G. (2023, February 1). FRONTIERS IN PHARMACOLOGY, Vol. 14.

By: R. Rizzo*, F. Caccuri*, G. Valacchi n & G. Zauli*

co-author countries: Italy 🇮🇹 Saudi Arabia 🇸🇦 United States of America 🇺🇸
author keywords: cell cycle; SARS-CoV-2; p53; cytokine storm; idasanutlin
Sources: Web Of Science, ORCID
Added: March 13, 2023

2023 journal article

Evaluation of Anti-Oxinflammatory and ACE-Inhibitory Properties of Protein Hydrolysates Obtained from Edible Non-Mulberry Silkworm Pupae (Antheraea assama and Philosomia ricinii)

NUTRIENTS, 15(4).

co-author countries: India 🇮🇳 Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: non-mulberry silkworm pupae; angiotensin converting enzyme-inhibitory peptides; antioxidative peptides; ultrafiltration; anti-inflammatory peptides
MeSH headings : Animals; Angiotensin-Converting Enzyme Inhibitors / pharmacology; Antioxidants / pharmacology; Protein Hydrolysates / pharmacology; Bombyx; Pupa; Endothelial Cells; Lipopolysaccharides; Peptides / pharmacology; Hypertension; Hydrolysis
Sources: Web Of Science, ORCID
Added: March 20, 2023

2023 article

INFLAMMASOMES REGULATION BY ENVIRONMENTAL POLLUTANTS IN HUMAN SKIN

Ferrara, F., Pecorelli, A., Guiotto, A., Vallese, A., Cordone, V., Benedusi, M., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 38–39.

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 journal article

Identification of bromelain subfamily proteases encoded in the pineapple genome

SCIENTIFIC REPORTS, 13(1).

By: A. Yow n, H. Bostan n, R. Young*, G. Valacchi n, N. Gillitt, P. Perkins-Veazie n, Q. Xiang n, M. Iorizzo n

co-author countries: Honduras 🇭🇳 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 21, 2023

2023 journal article

Lipid-Based Nanosystems for the Topical Application of Ferulic Acid: A Comparative Study

PHARMACEUTICS, 15(7).

co-author countries: Germany 🇩🇪 Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: ferulic acid; antioxidant molecules; transferosomes; vesicles; monoolein aqueous dispersions; topical application; cryo-TEM
Sources: Web Of Science, ORCID
Added: October 10, 2023

2023 article

MITOCHONDRIAL DYSFUNCTION AND NLRP3 INFLAMMASOME ACTIVATION IN AUTISM SPECTRUM DISORDER

Vallese, A., Pecorelli, A., Cordone, V., Ferrara, F., Benedusi, M., Cervellati, F., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 20–20.

By: A. Vallese n, A. Pecorelli*, V. Cordone*, F. Ferrara*, M. Benedusi*, F. Cervellati*, J. Hayek*, G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 review

Moderate red wine intake and cardiovascular health protection: a literature review

[Review of ]. FOOD & FUNCTION, 14(14), 6346–6362.

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
MeSH headings : Male; Humans; Female; Wine / analysis; Cardiovascular Diseases / prevention & control; Alcoholic Beverages; Cardiovascular System; Antioxidants; Ethanol; Alcohol Drinking
Sources: Web Of Science, ORCID
Added: July 24, 2023

2023 journal article

Modulation of Cutaneous Carotenoid Content via Ozone Exposure

COSMETICS, 10(4).

By: F. Cervellati*, M. Benedusi*, A. Mastaloudis*, V. Nagliati* & G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: skin barrier; carotenoids; ozone exposure; Raman spectroscopy; statistics
Sources: Web Of Science, ORCID
Added: September 11, 2023

2023 journal article

Ox-inflammasome involvement in neuroinflammation

FREE RADICAL BIOLOGY AND MEDICINE, 207, 161–177.

By: A. Vallese*, V. Cordone*, A. Pecorelli* & G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: September 5, 2023

2023 article

OxInflammation in Alzheimer's disease

Cervellati, C., Zuliani, G., & Valacchi, G. (2023, December). NEURAL REGENERATION RESEARCH, Vol. 18, pp. 2709–2710.

By: C. Cervellati, G. Zuliani & G. Valacchi*

Sources: Web Of Science, ORCID
Added: October 23, 2023

2023 article

Protective role of Ibuprofen-Curcumin co-load nanomicelles against oxidative stress and inflammasome activation mediated by indoor pollution exposure in A549 cells

Garces, M., Pecorelli, A., Moretton, M., Magnani, N., Chiapetta, D., Alvarez, S., … Valacchi, G. (2023, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 208, pp. S151–S152.

By: M. Garces*, A. Pecorelli*, M. Moretton*, N. Magnani*, D. Chiapetta*, S. Alvarez*, P. Evelson*, G. Valacchi n

co-author countries: Argentina 🇦🇷 Italy 🇮🇹 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: January 2, 2024

2023 article

ROLE OF COENZYME Q10 IN MITOCHONDRIAL DYSFUNCTION AND OXIDATIVE DAMAGE IN RETT SYNDROME

Silvestri, S., Marcheggiani, F., Orlando, P., Cirilli, I., Mengarelli, F., Vallese, A., … Tiano, L. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 16–16.

By: S. Silvestri*, F. Marcheggiani*, P. Orlando*, I. Cirilli*, F. Mengarelli*, A. Vallese*, A. Pecorelli*, G. Valacchi*, L. Tiano*

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 article

THE POSSIBLE MODULATION OF NRF2 AND NF-KB CROSSTALK BY SULFORAPHANE IN THE PROGRESSION OF HUMAN MELANOMA

Benedusi, M., Canella, R., Vallese, A., Casoni, A., Guerra, M., Rispoli, G., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 57–57.

By: M. Benedusi*, R. Canella*, A. Vallese*, A. Casoni*, M. Guerra*, G. Rispoli*, F. Ferrara*, F. Cervellati*, G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 article

THE PROTECTIVE ROLE OF ENDOTHELIAL alpha 1AMPK IN AIRCRAFT NOISE-INDUCED VASCULAR DYSFUNCTION AND OXIDATIVE STRESS IS MEDIATED BY FASTING, EXERCISE AND PHARMACOLOGICAL TREATMENT

Cordone, V., Pecorelli, A., Ferrara, F., Guiotto, A., Hayek, J., Cervellati, C., … Valacchi, G. (2023, May 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 201, pp. 11–12.

By: V. Cordone, A. Pecorelli, F. Ferrara, A. Guiotto, J. Hayek, C. Cervellati, F. Amicarelli, G. Valacchi

co-author countries: Germany 🇩🇪 France 🇫🇷 Slovakia 🇸🇰
Sources: Web Of Science, ORCID
Added: June 19, 2023

2023 journal article

Tension as a key factor in skin responses to pollution

SCIENTIFIC REPORTS, 13(1).

By: E. Pambianchi n, Z. Hagenberg n, A. Pecorelli n, A. Pasqui*, J. Therrien n & G. Valacchi n

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: January 22, 2024

2023 article

The pathogenic axis between mitochondrial dysfunction and NLRP3 inflammasome activation in Autism Spectrum Disorder

Vallese, A., Pecorelli, A., Cordone, V., Ferrara, F., Benedusi, M., Cervellati, F., … Valacchi, G. (2023, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 208, pp. S49–S49.

By: A. Vallese*, A. Pecorelli*, V. Cordone*, F. Ferrara*, M. Benedusi*, F. Cervellati*, J. Hayek*, G. Valacchi n

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: November 24, 2023

2022 article

Aberrant Mitochondrial Bioenergetics Fuels Inflammasome Machinery in Autism Spectrum Disorder

Pecorelli, A., Francesca, F., Cordone, V., Guiotto, A., Cervellati, C., Hayek, J., & Valacchi, G. (2022, February 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 180, pp. 97–98.

By: A. Pecorelli n, F. Francesca n, V. Cordone*, A. Guiotto*, C. Cervellati*, J. Hayek*, G. Valacchi n

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: April 25, 2022

2022 journal article

Biological activity of new bioactive steroids deriving from biotransformation of cortisone

MICROBIAL CELL FACTORIES, 21(1).

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: Biotransformations; Cortisone; Steroids; Neuroprotective; Anti-inflammatory; Antioxidant
MeSH headings : Cortisone; Antioxidants / pharmacology; Biotransformation; Steroids; Anti-Inflammatory Agents / pharmacology; Anti-Inflammatory Agents / therapeutic use
Sources: Web Of Science, ORCID
Added: December 5, 2022

2022 journal article

Chemoresistive Sensors for Cellular Type Discrimination Based on Their Exhalations

NANOMATERIALS, 12(7).

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷
author keywords: chemoresistivity; nanostructures; sensors; cells; tumor; VOCs
Sources: Web Of Science, ORCID
Added: April 25, 2022

2022 journal article

Dimethyl Fumarate-Loaded Transethosomes: A Formulative Study and Preliminary Ex Vivo and In Vivo Evaluation

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 23(15).

By: F. Ferrara*, M. Benedusi*, F. Cervellati*, M. Sguizzato*, L. Montesi*, A. Bondi*, M. Drechsler*, W. Pula*, G. Valacchi*, E. Esposito*

co-author countries: Germany 🇩🇪 Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: dimethyl fumarate; cryogenic transmission electron microscopy; wound healing; transethosomes; transdermal delivery
MeSH headings : Administration, Cutaneous; Dimethyl Fumarate / pharmacology; Drug Delivery Systems / methods; Humans; Liposomes / chemistry; Phosphatidylcholines / metabolism; Skin / metabolism; Skin Absorption
Sources: Web Of Science, ORCID
Added: August 29, 2022

2022 article

Editorial: Angiogenesis and Nutraceuticals

Trabalzini, L., Tundis, R., Valacchi, G., Evelson, P. A., & Finetti, F. (2022, May 30). FRONTIERS IN PHARMACOLOGY, Vol. 13.

By: L. Trabalzini*, R. Tundis*, G. Valacchi n, P. Evelson* & F. Finetti*

co-author countries: Argentina 🇦🇷 Italy 🇮🇹 United States of America 🇺🇸
author keywords: angiogenesis; nutraceuticals; endothelial cells; foods; food-derived products
Sources: Web Of Science, ORCID
Added: June 20, 2022

2022 journal article

Ethosomes and Transethosomes as Cutaneous Delivery Systems for Quercetin: A Preliminary Study on Melanoma Cells

PHARMACEUTICS, 14(5).

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: quercetin; ethosome; transethosome; in vitro release test; in vitro permeation test; Franz cell; wound healing; migration assay
Sources: Web Of Science, ORCID
Added: June 13, 2022

2022 journal article

Extra Virgin Olive Oil Extracts of Indigenous Southern Tuscany Cultivar Act as Anti-Inflammatory and Vasorelaxant Nutraceuticals

ANTIOXIDANTS, 11(3).

By: L. Pozzetti*, F. Ferrara*, L. Marotta*, S. Gemma*, S. Butini*, M. Benedusi*, F. Fusi*, A. Ahmed* ...

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷
author keywords: olive oil; traceability quality; food origin; luteolin; oleuropein; CaCo-2 cells; Nrf2; NF-kappa B
Sources: Web Of Science, ORCID
Added: April 18, 2022

2022 article

Inflammasome involvement in CS-induced damage in HaCaT keratinocytes

Prieux, R., Ferrara, F., Cervellati, F., Guiotto, A., Benedusi, M., & Valacchi, G. (2022, April 15). IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, Vol. 4.

By: R. Prieux*, F. Ferrara*, F. Cervellati*, A. Guiotto*, M. Benedusi* & G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
MeSH headings : Animals; Cytokines / metabolism; Inflammasomes / metabolism; Interleukin-1beta / metabolism; Keratinocytes / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Skin / metabolism
Sources: Web Of Science, ORCID
Added: May 2, 2022

2022 article

Involvement Of Ferroptosis In Rett Syndrome

Guiotto, A., Cordone, V., Benedusi, M., Cervellati, F., Cervellati, C., Hayek, J., … Pecorelli, A. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.

By: A. Guiotto, V. Cordone, M. Benedusi, F. Cervellati, C. Cervellati, J. Hayek, G. Valacchi*, A. Pecorelli*

Sources: Web Of Science, ORCID
Added: March 6, 2023

2022 article

Loss of Scavenger Receptor B1 (SR-B1) in Brain of a Rett Syndrome Mouse Model

Pecorelli, A., Ferrara, F., Guiotto, A., Vallese, A., Cordone, V., Belmonte, G., … Valacchi, G. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.

By: A. Pecorelli*, F. Ferrara*, A. Guiotto, A. Vallese*, V. Cordone, G. Belmonte, J. Hayek, C. Cervellati, G. Valacchi*

Sources: Web Of Science, ORCID
Added: March 6, 2023

2022 journal article

MicroRNA Alterations Induced in Human Skin by Diesel Fumes, Ozone, and UV Radiation

JOURNAL OF PERSONALIZED MEDICINE, 12(2).

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: microRNAs; environmental risk factors; cutaneous tissues; ozone exposure
Sources: Web Of Science, ORCID
Added: April 4, 2022

2022 article

Mutations Specific Redox Regulation Pathway In Rett Syndrome By The Use Of Transcriptomics And Proteomics Approaches

Pasqui, A., Cicaloni, V., Tinti, L., Mori, A., Bruttini, M., Pecorelli, A., … Valacchi, G. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.

By: A. Pasqui*, V. Cicaloni, L. Tinti, A. Mori, M. Bruttini, A. Pecorelli*, C. Tinti, F. Dotta, S. Laura, G. Valacchi*

co-author countries: Italy 🇮🇹
Sources: Web Of Science, ORCID
Added: March 6, 2023

2022 review

Oxidative-Stress-Sensitive microRNAs in UV-Promoted Development of Melanoma

[Review of ]. CANCERS, 14(13).

By: A. Pecorelli n & G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: skin cancer; sunlight; redox imbalance; miRNome; mutations; epigenome
Sources: Web Of Science, ORCID
Added: July 26, 2022

2022 journal article

The constitutive activation of TLR4-IRAK1-NF kappa B axis is involved in the early NLRP3 inflammasome response in peripheral blood mononuclear cells of Rett syndrome patients

FREE RADICAL BIOLOGY AND MEDICINE, 181, 1–13.

By: V. Cordone*, F. Ferrara*, A. Pecorelli n, A. Guiotto*, A. Vitale*, F. Amicarelli*, C. Cervellati*, J. Hayek*, G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: MeCP2; p65; Oxinflammation; Interleukin-18; Interleukin-1 beta
MeSH headings : Humans; Inflammasomes / genetics; Inflammasomes / metabolism; Interleukin-1 Receptor-Associated Kinases / genetics; Interleukin-1beta / genetics; Interleukin-1beta / metabolism; Leukocytes, Mononuclear / metabolism; NF-kappa B / genetics; NF-kappa B / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / genetics; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Rett Syndrome / genetics; Rett Syndrome / metabolism; Toll-Like Receptor 4 / genetics
Sources: Web Of Science, ORCID
Added: March 14, 2022

2022 journal article

Ubiquitination as a key regulatory mechanism for O-3-induced cutaneous redox inflammasome activation

REDOX BIOLOGY, 56.

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸

Contributors: F. Ferrara*, V. Cordone*, A. Pecorelli*, M. Benedusi*, E. Pambianchi*, A. Guiotto*, A. Vallese*, F. Cervellati*, G. Valacchi*

author keywords: Inflammasomes; OxInflammation; Proteasome; UBR2; N-end rule pathway
MeSH headings : Adaptor Proteins, Signal Transducing / metabolism; Air Pollutants; Apoptosis Regulatory Proteins / genetics; Catalase / metabolism; Cytokines / metabolism; Environmental Pollutants; Humans; Hydrogen Peroxide / metabolism; Inflammasomes / metabolism; NLR Proteins / metabolism; Oxidation-Reduction; Ozone / metabolism; Particulate Matter; Reactive Oxygen Species / metabolism; Ubiquitin-Protein Ligases / metabolism; Ubiquitination
Sources: Web Of Science, ORCID
Added: September 12, 2022

2022 article

Ubiquitination as a key regulatory mechanism for O3-induced cutaneous redox Inflammasome activation

Ferrara, F., Cordone, V., Pecorelli, A., Benedusi, M., Pambianchi, E., Guiotto, A., … Valacchi, G. (2022, November 1). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 192.

By: F. Ferrara*, V. Cordone*, A. Pecorelli n, M. Benedusi*, E. Pambianchi n, A. Guiotto*, A. Vallese*, F. Cervellati*, G. Valacchi n

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: March 6, 2023

2022 review

Ultraviolet Light Protection: Is It Really Enough?

[Review of ]. ANTIOXIDANTS, 11(8).

By: P. Farris* & G. Valacchi*

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: skin aging; ultraviolet light; solar radiation; pollution; reactive oxygen species; oxidative stress; antioxidants; chelators
Sources: Web Of Science, ORCID
Added: September 6, 2022

2021 journal article

"Plurethosome" as Vesicular System for Cutaneous Administration of Mangiferin: Formulative Study and 3D Skin Tissue Evaluation

PHARMACEUTICS, 13(8).

By: M. Sguizzato*, F. Ferrara*, P. Mariani*, A. Pepe*, R. Cortesi*, N. Huang*, F. Simeliere*, P. Boldrini* ...

co-author countries: France 🇫🇷 Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: phosphatidylcholine; poloxamer; mangiferin; in vitro diffusion; antioxidant
Sources: Web Of Science, ORCID
Added: September 7, 2021

2021 journal article

Alaskan Bog Blueberry (Vaccinium uliginosum) Extract as an Innovative Topical Approach to Prevent UV-Induced Skin Damage

COSMETICS, 8(4).

By: E. Pambianchi n, Z. Hagenberg n, A. Pecorelli n, M. Grace n, J. Therrien n, M. Lila n, G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: cosmeceuticals; environmental stressor; oxidation; inflammation; antioxidant; OxInflammation; phytochemicals
Sources: Web Of Science, ORCID
Added: December 2, 2021

2021 article

Alteration of cellular defensive response and a possible involvement of ferroptosis cell death in Rett syndrome disorder

Guiotto, A., Cordone, V., Benedusi, M., Cervellati, F., Hayek, J., Cervellati, C., … Pecorelli, A. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.

By: A. Guiotto*, V. Cordone*, M. Benedusi*, F. Cervellati*, J. Hayek*, C. Cervellati*, G. Valacchi*, A. Pecorelli*

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: April 5, 2021

2021 journal article

Alterations in oxygen metabolism are associated to lung toxicity triggered by silver nanoparticles exposure

FREE RADICAL BIOLOGY AND MEDICINE, 166, 324–336.

By: M. Garces*, N. Magnani*, A. Pecorelli*, V. Calabro*, T. Marchini*, L. Caceres*, E. Pambianchi*, J. Galdoporpora* ...

co-author countries: Argentina 🇦🇷 Italy 🇮🇹 Korea (Republic of) 🇰🇷
author keywords: Nanoparticles; Lung epithelium; Nanotoxicology; Oxidative metabolism; NADPH oxidase; Mitochondria
MeSH headings : Animals; Hydrogen Peroxide; Lung; Metal Nanoparticles / toxicity; Mice; Oxygen; Silver
Sources: Web Of Science, ORCID
Added: April 19, 2021

2021 review

Altered Bone Status in Rett Syndrome

[Review of ]. LIFE-BASEL, 11(6).

By: A. Pecorelli n, V. Cordone*, M. Schiavone n, C. Caffarelli*, C. Cervellati*, G. Cerbone*, S. Gonnelli*, J. Hayek*, G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: MeCP2; bone mineral density; bone metabolism; osteoblast; WNT pathway
Sources: Web Of Science, ORCID
Added: July 12, 2021

2021 article

BACE1 role in Alzheimer's disease and other dementias: from the theory to the practice

Cervellati, C., Valacchi, G., & Zuliani, G. (2021, December). NEURAL REGENERATION RESEARCH, Vol. 16, pp. 2407–2408.

By: C. Cervellati*, G. Valacchi* & G. Zuliani

co-author countries: Italy 🇮🇹
Sources: Web Of Science, ORCID
Added: June 10, 2021

2021 review

Bench approaches to study the detrimental cutaneous impact of tropospheric ozone

[Review of ]. JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, 31(1), 137–148.

By: B. Petracca*, B. Rothen-Rutishauser*, G. Valacchi n & M. Eeman

co-author countries: Switzerland 🇨🇭 Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: Environmental pollution; Skin; 3D skin tissue model; Oxidative stress; Skin protection
MeSH headings : Air Pollutants / adverse effects; Air Pollutants / analysis; Cities; Humans; Lipid Peroxidation; Oxidative Stress; Ozone / adverse effects; Ozone / analysis; Skin / metabolism
Sources: Web Of Science, ORCID
Added: November 24, 2020

2021 journal article

Circadian Deregulation as Possible New Player in Pollution-Induced Tissue Damage

ATMOSPHERE, 12(1).

By: M. Benedusi*, E. Frigato*, C. Bertolucci* & G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: circadian clock; pollution; antioxidant system
Sources: Web Of Science, ORCID
Added: February 15, 2021

2021 review

Connection between the Altered HDL Antioxidant and Anti-Inflammatory Properties and the Risk to Develop Alzheimer's Disease: A Narrative Review

[Review of ]. OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2021.

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
MeSH headings : Alzheimer Disease / etiology; Alzheimer Disease / metabolism; Alzheimer Disease / pathology; Animals; Anti-Inflammatory Agents / metabolism; Antioxidants / metabolism; Humans; Inflammation / complications; Lipoproteins, HDL / metabolism; Oxidative Stress
Sources: Web Of Science, ORCID
Added: February 22, 2021

2021 journal article

Cultivating a Three-dimensional Reconstructed Human Epidermis at a Large Scale

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 5(171).

By: I. Dijkhoff*, B. Petracca*, R. Prieux*, G. Valacchi n, B. Rothen-Rutishauser* & M. Eeman*

co-author countries: Belgium 🇧🇪 Switzerland 🇨🇭 Italy 🇮🇹 United States of America 🇺🇸
MeSH headings : Cell Differentiation; Cells, Cultured; Coculture Techniques; Epidermal Cells; Epidermis; Filaggrin Proteins; Humans; Keratinocytes; Skin
Sources: Web Of Science, ORCID
Added: June 21, 2021

2021 journal article

Deferoxamine Treatment Improves Antioxidant Cosmeceutical Formulation Protection against Cutaneous Diesel Engine Exhaust Exposure

ANTIOXIDANTS, 10(12).

By: E. Pambianchi n, F. Ferrara*, A. Pecorelli n, M. Benedusi*, H. Choudhary*, J. Therrien*, G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: cosmeceuticals; pollution; iron-chelator
Sources: Web Of Science, ORCID
Added: January 24, 2022

2021 article

Deregulated inflammasome response in Rett syndrome

Cordone, V., Pecorelli, A., Falone, S., Hayek, J., Amicarelli, F., & Valacchi, G. (2021, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 177.

By: V. Cordone*, A. Pecorelli*, S. Falone*, J. Hayek*, F. Amicarelli* & G. Valacchi*

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷
Sources: Web Of Science, ORCID
Added: February 21, 2022

2021 journal article

Ethosomes and Transethosomes for Mangiferin Transdermal Delivery

ANTIOXIDANTS, 10(5).

co-author countries: Germany 🇩🇪 Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: ethosomes; transethosomes; mangiferin; franz cell; antioxidants
Sources: Web Of Science, ORCID
Added: June 10, 2021

2021 journal article

Formulative Study and Intracellular Fate Evaluation of Ethosomes and Transethosomes for Vitamin D3 Delivery

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 22(10).

co-author countries: Germany 🇩🇪 Italy 🇮🇹 United States of America 🇺🇸
author keywords: cell culture; cholecalciferol; cryogenic transmission electron microscopy; in vitro test; light microscopy; lipid nanocarriers; transmission electron microscopy
MeSH headings : Cell Line; Chemistry, Pharmaceutical / methods; Cholecalciferol / administration & dosage; Cholecalciferol / metabolism; Cholecalciferol / pharmacology; Drug Carriers / chemistry; Drug Delivery Systems / methods; Fibroblasts / drug effects; Humans; Keratinocytes / drug effects; Lipids / chemistry; Liposomes / chemistry; Myoblasts / drug effects; Nanocapsules / chemistry; Pilot Projects; Skin / metabolism; Skin Absorption; Surface-Active Agents / metabolism
Sources: Web Of Science, ORCID
Added: June 28, 2021

2021 journal article

Impaired mitochondrial quality control in Rett Syndrome

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 700.

By: I. Crivellari*, A. Pecorelli n, V. Cordone*, S. Marchi*, P. Pinton*, J. Hayek*, C. Cervellati*, G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: RTT Syndrome; Oxidative stress; Mitochondrial quality control; Mitophagy; Apoptosis
MeSH headings : Adolescent; Adult; Apoptosis; Caspase 3 / genetics; Caspase 3 / metabolism; Caspase 7 / genetics; Caspase 7 / metabolism; Child; Dynamins / genetics; Dynamins / metabolism; Female; Fibroblasts / metabolism; Fibroblasts / pathology; GTP Phosphohydrolases / genetics; GTP Phosphohydrolases / metabolism; Humans; Membrane Proteins / genetics; Membrane Proteins / metabolism; Methyl-CpG-Binding Protein 2 / genetics; Methyl-CpG-Binding Protein 2 / metabolism; Mitochondria / genetics; Mitochondria / metabolism; Mitochondria / pathology; Mitochondrial Membrane Transport Proteins / genetics; Mitochondrial Membrane Transport Proteins / metabolism; Mitochondrial Proteins / genetics; Mitochondrial Proteins / metabolism; Mitophagy; Oxidation-Reduction; Rett Syndrome / genetics; Rett Syndrome / metabolism; Rett Syndrome / pathology
Sources: Web Of Science, ORCID
Added: March 15, 2021

2021 article

Improper enzymatic defensive responses in Rett syndrome disorder

Guiotto, A., Cordone, V., Benedusi, M., Cervellati, F., Hayek, J., Cervellati, C., … Pecorelli, A. (2021, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 177.

By: A. Guiotto*, V. Cordone*, M. Benedusi*, F. Cervellati*, J. Hayek*, C. Cervellati*, G. Valacchi n, A. Pecorelli n

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: February 21, 2022

2021 journal article

Inflammasome Activation in Pollution-Induced Skin Conditions

PLASTIC AND RECONSTRUCTIVE SURGERY, 147(1S-2), 15S–24S.

By: F. Ferrara*, R. Prieux*, B. Woodby* & G. Valacchi*

co-author countries: Korea (Republic of) 🇰🇷 Netherlands 🇳🇱 United States of America 🇺🇸
MeSH headings : Air Pollutants / adverse effects; Air Pollution / adverse effects; Animals; Dermatitis / immunology; Dermatitis / pathology; Dermatitis / prevention & control; Disease Models, Animal; Environmental Exposure / adverse effects; Furans; Heterocyclic Compounds, 4 or More Rings / pharmacology; Heterocyclic Compounds, 4 or More Rings / therapeutic use; Humans; Indenes; Inflammasomes / antagonists & inhibitors; Inflammasomes / immunology; Inflammasomes / metabolism; Interleukin-18 / metabolism; Interleukin-1beta / metabolism; Mice; NLR Family, Pyrin Domain-Containing 3 Protein / antagonists & inhibitors; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Nitriles / pharmacology; Nitriles / therapeutic use; Skin / drug effects; Skin / immunology; Skin / pathology; Skin Aging / immunology; Sulfonamides; Sulfones / pharmacology; Sulfones / therapeutic use
Sources: Web Of Science, ORCID
Added: July 6, 2021

2021 article

Mitochondrial dynamics and quality control pathways impairment in Rett Syndrome and Autism Spectrum Disorder

Pecorelli, A., Guiotto, A., Cordone, V., Cervellati, F., Benedusi, M., Cervellati, C., … Valacchi, G. (2021, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 177, pp. S17–S18.

By: A. Pecorelli n, A. Guiotto*, V. Cordone*, F. Cervellati*, M. Benedusi*, C. Cervellati*, J. Hayek*, G. Valacchi n

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: February 28, 2022

2021 article

Mitochondrial dysfunction fuels inflammasome machinery in Autism Spectrum Disorder

Pecorelli, A., Cordone, V., Guiotto, A., Cervellati, F., Benedusi, M., Cervellati, C., … Valacchi, G. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.

By: A. Pecorelli n, V. Cordone*, A. Guiotto*, F. Cervellati*, M. Benedusi*, C. Cervellati*, J. Hayek*, G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: April 5, 2021

2021 article

NALP1 involvement in cigarette smoke induces cutaneous inflammation

Prieux, R., Benedusi, M., Ferrara, F., Guiotto, A., Cervellati, F., & Valacchi, G. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.

By: R. Prieux, M. Benedusi, F. Ferrara, A. Guiotto, F. Cervellati & G. Valacchi

co-author countries: Croatia 🇭🇷 Poland 🇵🇱
Sources: Web Of Science, ORCID
Added: April 5, 2021

2021 journal article

Novel Spray Dried Algae-Rosemary Particles Attenuate Pollution-Induced Skin Damage

MOLECULES, 26(13).

By: R. Hoskin n, E. Pambianchi n, A. Pecorelli n, M. Grace n, J. Therrien*, G. Valacchi n, M. Lila n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: cosmeceuticals; pollution; phytochemicals; herbs
MeSH headings : Antioxidants / chemistry; Antioxidants / pharmacology; Cells, Cultured; Chlorella / chemistry; Cinnamates / chemistry; Depsides / chemistry; Environmental Exposure / adverse effects; Filaggrin Proteins; Humans; Rosmarinus / chemistry; Skin / injuries; Skin / metabolism; Skin / pathology; Skin Aging / drug effects
Sources: Web Of Science, ORCID
Added: June 23, 2021

2021 journal article

Oxidative metabolism in the cardiorespiratory system after an acute exposure to nickel-doped nanoparticles in mice

TOXICOLOGY, 464.

By: M. Garces*, T. Marchini*, L. Caceres*, V. Calabro*, A. Mebert*, M. Victoria Tuttolomondo*, T. Vico*, V. Vanasco* ...

co-author countries: Argentina 🇦🇷 Italy 🇮🇹
author keywords: nanoparticles; nickel; reactive oxygen species; oxidative stress; NADPH oxidase
MeSH headings : Animals; Antioxidants / metabolism; Female; Lung / drug effects; Lung / metabolism; Male; Metal Nanoparticles / chemistry; Metal Nanoparticles / toxicity; Mice; Mitochondria / drug effects; Nickel / chemistry; Oxidation-Reduction / drug effects; Oxidative Stress / drug effects; Oxygen Consumption / drug effects; Silicon Dioxide / chemistry
Sources: Web Of Science, ORCID
Added: November 29, 2021

2021 article

Proteome composition and profiling of bioactive peptides of edible Antheraea assamensis pupae by sequential enzymatic digestion and kinetic modeling of in vitro gastrointestinal digestion

Sarkar, P., Valacchi, G., & Duary, R. K. (2021, October 28). EUROPEAN FOOD RESEARCH AND TECHNOLOGY, Vol. 10.

By: P. Sarkar*, G. Valacchi* & R. Duary*

co-author countries: India 🇮🇳 Italy 🇮🇹
author keywords: Insect hydrolysate; Papain; Thermolysin; Gastrointestinal digestion; Free amino acids; Enzyme kinetics
Sources: Web Of Science, ORCID
Added: November 8, 2021

2021 review

SARS-CoV-2 infection, COVID-19 pathogenesis, and exposure to air pollution: What is the connection?

[Review of ]. ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1486(1), 15–38.

By: B. Woodby n, M. Arnold* & G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: air pollution; coronavirus; particulate matter; ozone; nitrogen dioxide; viral infection
MeSH headings : Adaptive Immunity; Air Pollutants / adverse effects; Air Pollution / adverse effects; COVID-19 / etiology; COVID-19 / immunology; COVID-19 / virology; Host Microbial Interactions; Humans; Immunity, Innate; Models, Biological; Pandemics; Particulate Matter / adverse effects; Receptors, Virus / physiology; Respiratory System / physiopathology; SARS-CoV-2 / immunology; SARS-CoV-2 / pathogenicity; SARS-CoV-2 / physiology; Toll-Like Receptors / physiology; Virus Internalization; Virus Replication
Sources: Web Of Science, ORCID
Added: October 19, 2020

2021 journal article

Selective Fatty Acid Amide Hydrolase Inhibitors as Potential Novel Antiepileptic Agents

ACS CHEMICAL NEUROSCIENCE, 12(9), 1716–1736.

By: A. Grillo*, F. Fezza*, G. Chemi*, R. Colangeli*, S. Brogi*, D. Fazio*, S. Federico*, A. Papa* ...

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 Italy 🇮🇹 Korea (Republic of) 🇰🇷 Malta 🇲🇹 United States of America 🇺🇸
author keywords: Endocannabinoid system; fatty acid amide hydrolase; enzyme inhibitors; selective inhibitors; epilepsy; temporal lobe epilepsy; seizures
MeSH headings : Amidohydrolases; Anticonvulsants / pharmacology; Endocannabinoids; Enzyme Inhibitors / pharmacology; Humans; Seizures
Sources: Web Of Science, ORCID
Added: June 10, 2021

2021 article

The role of pulmonary ORCC and CLC-2 channels in the response to oxidative stress

Canella, R., Benedusi, M., Martini, M., Guiotto, A., Cervellati, F., & Valacchi, G. (2021, May 7). MOLECULAR & CELLULAR TOXICOLOGY, Vol. 5.

By: R. Canella*, M. Benedusi*, M. Martini*, A. Guiotto*, F. Cervellati* & G. Valacchi*

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷
author keywords: Human lung epithelial cells; Chloride channels; Ozone; Oxidative stress; Patch clamp technique
Sources: Web Of Science, ORCID
Added: June 10, 2021

2021 article

Ubiquitination as a key regulatory mechanism for O-3-induced cutaneous redox inflammasome activation

Ferrara, F., Pecorelli, A., Benedusi, M., Pambianchi, E., Guiotto, A., Cervellati, F., & Valacchi, G. (2021, March). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 165.

By: F. Ferrara, A. Pecorelli, M. Benedusi, E. Pambianchi, A. Guiotto, F. Cervellati, G. Valacchi

co-author countries: Portugal 🇵🇹
Sources: Web Of Science, ORCID
Added: April 5, 2021

2020 journal article

A proteomics approach to further highlight the altered inflammatory condition in Rett syndrome

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 696.

By: V. Cicaloni*, A. Pecorelli n, V. Cordone*, L. Tinti*, M. Rossi*, J. Hayek*, L. Salvini*, C. Tinti*, G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: Rare disease; Rett syndrome; Inflammatory status; NLRP3 inflammasome; Mass spectrometry-based proteomics
MeSH headings : Adult; Female; Fibroblasts / chemistry; Humans; Inflammation / complications; Inflammation / metabolism; Protein Interaction Maps; Proteome / analysis; Proteome / metabolism; Proteomics; Rett Syndrome / complications; Rett Syndrome / metabolism; Young Adult
Sources: Web Of Science, ORCID
Added: January 19, 2021

2020 journal article

Alterations of mitochondrial bioenergetics, dynamics, and morphology support the theory of oxidative damage involvement in autism spectrum disorder

FASEB JOURNAL, 34(5), 6521–6538.

By: A. Pecorelli*, F. Ferrara*, N. Messano*, V. Cordone*, M. Schiavone*, F. Cervellati*, B. Woodby*, C. Cervellati*, J. Hayek*, G. Valacchi*

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: 4-hydroxynonenal; fission; fusion; mitophagy; nuclear factor erythroid 2-related factor 2
MeSH headings : Adolescent; Adult; Autism Spectrum Disorder / metabolism; Autism Spectrum Disorder / pathology; Case-Control Studies; Child; Energy Metabolism; Female; Fibroblasts / metabolism; Fibroblasts / pathology; Humans; Male; Mitochondria / metabolism; Mitochondria / pathology; Mitochondrial Dynamics; Mitochondrial Proteins / metabolism; Oxidative Stress; Young Adult
Sources: Web Of Science, ORCID
Added: April 20, 2020

2020 journal article

Altered inflammasome machinery as a key player in the perpetuation of Rett syndrome oxinflammation

REDOX BIOLOGY, 28.

By: A. Pecorelli*, V. Cordone*, N. Messano*, C. Zhang*, S. Falone*, F. Amicarelli*, J. Hayek*, G. Valacchi*

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: NLRP3; ASC; Inflammatory status; Cytokines; MeCP2
MeSH headings : Biomarkers; Cytokines / metabolism; Disease Susceptibility; Fibroblasts / metabolism; Fluorescent Antibody Technique; Humans; Inflammasomes / metabolism; Inflammation Mediators / metabolism; Interleukin-1beta / metabolism; NF-kappa B / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Protein Transport; Rett Syndrome / etiology; Rett Syndrome / metabolism
Sources: Web Of Science, ORCID
Added: December 30, 2019

2020 journal article

Circadian Clock and OxInflammation: Functional Crosstalk in Cutaneous Homeostasis

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2020.

By: E. Frigato*, M. Benedusi*, A. Guiotto*, C. Bertolucci* & G. Valacchi*

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
MeSH headings : Cells, Cultured; Circadian Clocks / physiology; Homeostasis; Humans; Inflammation / metabolism; Inflammation / pathology; Keratinocytes / cytology; Keratinocytes / metabolism; Skin / metabolism; Skin / pathology
Sources: Web Of Science, ORCID
Added: May 26, 2020

2020 journal article

Defective proteasome biogenesis into skin fibroblasts isolated from Rett syndrome subjects with MeCP2 non-sense mutations

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 1866(7).

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: Rett syndrome; Skin primary fibroblasts; Proteasome; alpha-Ring; PAC1; PAC2
MeSH headings : Codon, Nonsense / genetics; Dual Specificity Phosphatase 2 / genetics; Fibroblasts / metabolism; Gene Expression Regulation; Genetic Diseases, X-Linked / genetics; Genetic Diseases, X-Linked / pathology; Humans; Methyl-CpG-Binding Protein 2 / genetics; Neurodevelopmental Disorders / genetics; Neurodevelopmental Disorders / pathology; Primary Cell Culture; Proteasome Endopeptidase Complex / genetics; Proteolysis; Rett Syndrome / genetics; Rett Syndrome / pathology; Skin / metabolism; Skin / pathology; Ubiquitin / genetics
Sources: Web Of Science, ORCID
Added: June 15, 2020

2020 journal article

Ethosomes for Coenzyme Q10 Cutaneous Administration: From Design to 3D Skin Tissue Evaluation

ANTIOXIDANTS, 9(6).

co-author countries: Germany 🇩🇪 Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: ethosome; ubiquinone; H2O2; penetration enhancers; dermal administration; reconstituted human epidermis; small angle X-ray scattering
Sources: Web Of Science, ORCID
Added: August 10, 2020

2020 journal article

Gallic acid loaded poloxamer gel as new adjuvant strategy for melanoma: A preliminary study

COLLOIDS AND SURFACES B-BIOINTERFACES, 185.

By: M. Sguizzato*, G. Valacchi*, A. Pecorelli*, P. Boldrini*, F. Simeliere*, N. Huang*, R. Cortesi*, E. Esposito*

co-author countries: France 🇫🇷 Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: Biocompatible polymers; Polymer gels; In vitro diffusion; Polymer membranes; Gallic acid; Franz cell
MeSH headings : Adjuvants, Immunologic / pharmacology; Adjuvants, Immunologic / therapeutic use; Cell Line; Cell Movement / drug effects; Diffusion; Elasticity; Gallic Acid / pharmacology; Gallic Acid / therapeutic use; Gels / chemistry; Humans; Kinetics; Melanoma / drug therapy; Phase Transition; Poloxamer / chemistry; Rheology; Temperature; Viscosity; Wound Healing / drug effects
Sources: Web Of Science, ORCID
Added: January 13, 2020

2020 review

Impact of airborne particulate matter on skin: a systematic review from epidemiology to in vitro studies

[Review of ]. PARTICLE AND FIBRE TOXICOLOGY, 17(1).

By: I. Dijkhoff*, B. Drasler*, B. Karakocak*, A. Petri-Fink*, G. Valacchi n, M. Eeman, B. Rothen-Rutishauser*

co-author countries: Switzerland 🇨🇭 Italy 🇮🇹 United States of America 🇺🇸
author keywords: Particulate matter; Air pollution; Urban pollution; Skin models; Skin; In vitro studies; In vivo studies; Oxidative stress; Inflammation; Barrier dysfunction
MeSH headings : Air Pollutants / toxicity; Air Pollution; Humans; Oxidative Stress; Particulate Matter / toxicity; Reactive Oxygen Species; Skin / drug effects
Sources: Web Of Science, ORCID
Added: August 24, 2020

2020 journal article

Increased blood BACE1 activity as a potential common pathogenic factor of vascular dementia and late onset Alzheimer's disease

SCIENTIFIC REPORTS, 10(1).

By: G. Zuliani*, A. Trentini*, V. Rosta*, R. Guerrini*, S. Pacifico*, S. Bonazzi*, A. Guiotto*, A. Passaro* ...

co-author countries: Italy 🇮🇹
MeSH headings : Aged; Aged, 80 and over; Alzheimer Disease / blood; Alzheimer Disease / diagnosis; Amyloid Precursor Protein Secretases / blood; Aspartic Acid Endopeptidases / blood; Dementia, Vascular / blood; Dementia, Vascular / diagnosis; Female; Humans; Male
Sources: Web Of Science, ORCID
Added: October 12, 2020

2020 journal article

Inflammation in Neurological Disorders: The Thin Boundary Between Brain and Periphery

ANTIOXIDANTS & REDOX SIGNALING, 33(3), 191–210.

By: C. Cervellati*, A. Trentini*, A. Pecorelli* & G. Valacchi*

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷
author keywords: Alzheimer's disease; inflammation; multiple sclerosis; vascular dementia
MeSH headings : Animals; Biomarkers; Blood-Brain Barrier / metabolism; Brain / metabolism; Brain / pathology; Disease Susceptibility; Dysbiosis; Humans; Inflammation / etiology; Inflammation / metabolism; Inflammation / pathology; Nervous System Diseases / etiology; Nervous System Diseases / metabolism; Nervous System Diseases / pathology; Oxidative Stress; Peripheral Nerves / metabolism; Peripheral Nerves / pathology
Sources: Web Of Science, ORCID
Added: April 27, 2020

2020 journal article

KRIT1 as a possible new player in melanoma aggressiveness

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 691.

By: J. Ercoli*, F. Finetti*, B. Woodby*, G. Belmonte*, C. Miracco*, G. Valacchi*, L. Trabalzini*

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: KRIT1; Melanoma; Tumor suppressor; N-cadherin; Inflammation; beta-catenin
MeSH headings : Adult; Aged; Aged, 80 and over; Cell Line, Tumor; Cell Movement / physiology; Cell Nucleus / metabolism; Cell Proliferation / genetics; Down-Regulation; Female; Gene Knockdown Techniques / methods; Humans; KRIT1 Protein / genetics; KRIT1 Protein / metabolism; Male; Melanocytes / metabolism; Melanoma / metabolism; Melanoma / pathology; Middle Aged; beta Catenin / metabolism
Sources: Web Of Science, ORCID
Added: October 5, 2020

2020 journal article

Mechanisms involved in the unbalanced redox homeostasis in osteoblastic cellular model of Alkaptonuria

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 690.

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: Alkaptonuria; Osteoblast; Oxidative stress; Nrf2; Mitochondria; NADPH oxidase
MeSH headings : Alkaptonuria / metabolism; Cell Line; DNA-Binding Proteins / metabolism; Homeostasis / physiology; Homogentisic Acid / metabolism; Humans; Hydrogen Peroxide / metabolism; Mitochondria / metabolism; Mitochondria / ultrastructure; NADPH Oxidases / metabolism; NF-E2-Related Factor 2 / metabolism; Osteoblasts / cytology; Oxidation-Reduction; Oxidative Stress / physiology; Signal Transduction; Superoxide Dismutase / metabolism; Thioredoxins / metabolism
Sources: Web Of Science, ORCID
Added: January 19, 2021

2020 review

Mimicking cigarette smoke exposure to assess cutaneous toxicity

[Review of ]. TOXICOLOGY IN VITRO, 62.

By: R. Prieux*, M. Eeman, B. Rothen-Rutishauser* & G. Valacchi n

co-author countries: Switzerland 🇨🇭 Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: Cigarette smoke; Skin models; Inflammation; Oxidative stress; Psoriasis; Atopic dermatitis
MeSH headings : Animals; Humans; Skin / drug effects; Skin Diseases / chemically induced; Tobacco Products; Tobacco Smoke Pollution / adverse effects
Sources: Web Of Science, ORCID
Added: December 30, 2019

2020 journal article

Mixed Flavonoid Supplementation Attenuates Postexercise Plasma Levels of 4-Hydroxynonenal and Protein Carbonyls in Endurance Athletes

INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, 30(2), 112–119.

By: D. Nieman*, G. Valacchi*, L. Wentz*, F. Ferrara*, A. Pecorelli*, B. Woodby*, C. Sakaguchi*, A. Simonson*

co-author countries: Brazil 🇧🇷 Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: inflammation exercise; oxidative stress; peripheral blood mononuclear cells
Sources: Web Of Science, ORCID
Added: July 6, 2020

2020 journal article

NADPH oxidase and mitochondria are relevant sources of superoxide anion in the oxinflammatory response of macrophages exposed to airborne particulate matter

ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY, 205.

By: L. Caceres*, M. Paz*, M. Garces*, V. Calabro*, N. Magnani*, M. Martinefski*, P. Adami*, L. Caltana* ...

co-author countries: Argentina 🇦🇷 Italy 🇮🇹
author keywords: Air pollution; Oxidative stress; Inflammation; Mitochondria; NADPH oxidase; Macrophages
MeSH headings : Air Pollutants / toxicity; Animals; Antioxidants / metabolism; Coal Ash / toxicity; Hydrogen Peroxide / metabolism; Inflammation; Macrophages, Alveolar / drug effects; Macrophages, Alveolar / immunology; Macrophages, Alveolar / metabolism; Mice; Mitochondria / drug effects; Mitochondria / immunology; Mitochondria / metabolism; NADPH Oxidases / metabolism; Oxidation-Reduction; Oxidative Stress / drug effects; Oxidative Stress / immunology; Particulate Matter / toxicity; RAW 264.7 Cells; Superoxides / metabolism; Tumor Necrosis Factor-alpha / metabolism
Sources: Web Of Science, ORCID
Added: November 16, 2020

2020 journal article

Nanoparticulate Gels for Cutaneous Administration of Caffeic Acid

NANOMATERIALS, 10(5).

By: M. Sguizzato*, P. Mariani*, F. Ferrara*, M. Drechsler*, S. Hallan*, N. Huang*, F. Simeliere*, N. Khunti* ...

co-author countries: Germany 🇩🇪 France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Italy 🇮🇹 United States of America 🇺🇸
author keywords: solid lipid nanoparticles; caffeic acid; poloxamer; small angle X-ray scattering; cigarette smoke
Sources: Web Of Science, ORCID
Added: July 13, 2020

2020 journal article

Particulate Matter Induces Tissue OxInflammation: From Mechanism to Damage

ANTIOXIDANTS & REDOX SIGNALING, 33(4), 308–326.

By: G. Valacchi n, N. Magnani*, B. Woodby n, S. Maria Ferreira & P. Evelson*

co-author countries: Argentina 🇦🇷 Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: oxidative stress; inflammation; particulate matter; air pollution
MeSH headings : Air Pollution / adverse effects; Animals; Cytokines / metabolism; Disease Susceptibility; Humans; Inflammation / etiology; Inflammation / metabolism; Inflammation / pathology; Inflammation Mediators / metabolism; Oxidation-Reduction; Oxidative Stress; Particulate Matter / adverse effects; Reactive Oxygen Species / metabolism
Sources: Web Of Science, ORCID
Added: July 13, 2020

2020 journal article

Postexercise Inflammasome Activation and IL-1 beta Production Mitigated by Flavonoid Supplementation in Cyclists

INTERNATIONAL JOURNAL OF SPORT NUTRITION AND EXERCISE METABOLISM, 30(6), 396–404.

By: D. Nieman*, F. Ferrara*, A. Pecorelli*, B. Woodby*, A. Hoyle*, A. Simonson*, G. Valacchi*

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: cytokines; gasdermin D; IL-18; inflammation
Sources: Web Of Science, ORCID
Added: November 9, 2020

2020 journal article

Proteomic pro fi ling reveals mitochondrial alterations in Rett syndrome

FREE RADICAL BIOLOGY AND MEDICINE, 155, 37–48.

By: V. Cicaloni*, A. Pecorelli n, L. Tinti*, M. Rossi*, M. Benedusi*, C. Cervellati*, O. Spiga*, A. Santucci* ...

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
MeSH headings : Gene Expression Profiling; Humans; Methyl-CpG-Binding Protein 2 / genetics; Mutation; Proteome / genetics; Proteomics; Rett Syndrome / genetics
Sources: Web Of Science, ORCID
Added: July 6, 2020

2020 journal article

Redox regulation of cutaneous inflammasome by ozone exposure

FREE RADICAL BIOLOGY AND MEDICINE, 152, 561–570.

By: F. Ferrara*, E. Pambianchi*, A. Pecorelli*, B. Woodby*, N. Messano*, J. Therrien, M. Lila*, G. Valacchi*

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
MeSH headings : Caspase 1 / metabolism; Humans; Hydrogen Peroxide; Inflammasomes / metabolism; Interleukin-1beta / genetics; Interleukin-1beta / metabolism; NLR Family, Pyrin Domain-Containing 3 Protein / genetics; NLR Family, Pyrin Domain-Containing 3 Protein / metabolism; Oxidation-Reduction; Ozone / toxicity; Reactive Oxygen Species
Sources: Web Of Science, ORCID
Added: July 13, 2020

2020 journal article

Serum beta-secretase 1 (BACE1) activity as candidate biomarker for late-onset Alzheimer's disease

GEROSCIENCE, 42(1), 159–167.

By: C. Cervellati*, A. Trentini*, V. Rosta*, A. Passaro*, C. Bosi*, J. Sanz*, S. Bonazzi*, S. Pacifico* ...

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷
author keywords: Late-onset Alzheimer's disease; Mild cognitive impairment; Mixed dementia; Blood-based biomarkers; BACE1
MeSH headings : Alzheimer Disease / diagnosis; Amyloid Precursor Protein Secretases; Amyloid beta-Peptides; Aspartic Acid Endopeptidases; Biomarkers; Humans
Sources: Web Of Science, ORCID
Added: March 16, 2020

2020 article

Skin Health from the Inside Out

ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 11, Vol. 11, pp. 235–254.

By: B. Woodby n, K. Penta n, A. Pecorelli n, M. Lila n & G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: pollution; skin; diet; GI tract; inflammation; antioxidant; vitamins
MeSH headings : Antioxidants / metabolism; Humans; Reactive Oxygen Species / metabolism; Skin Physiological Phenomena
Sources: Web Of Science, ORCID
Added: April 27, 2020

2020 journal article

The PDE4 inhibitor CHF6001 affects keratinocyte proliferation via cellular redox pathways

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 685.

By: B. Woodby n, C. Sticozzi*, E. Pambianchi n, G. Villetti, M. Civelli, G. Valacchi n, F. Facchinetti

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: NOX; NF-kappa B; Cyclin D1; Skin; p21
MeSH headings : Aldehydes / metabolism; Cell Line; Cell Proliferation / drug effects; Cell Survival / drug effects; Cyclin D1 / metabolism; Humans; Keratinocytes / drug effects; Lipid Peroxidation / drug effects; NADPH Oxidases / metabolism; Oxidative Stress / drug effects; Phosphodiesterase 4 Inhibitors / pharmacology; Phosphodiesterase 4 Inhibitors / toxicity; Psoriasis / drug therapy; Sulfonamides / pharmacology; Sulfonamides / toxicity; Transcription Factor RelA / metabolism; para-Aminobenzoates / pharmacology; para-Aminobenzoates / toxicity
Sources: Web Of Science, ORCID
Added: May 8, 2020

2019 journal article

13-HODE, 9-HODE and ALOX15 as potential players in Rett syndrome OxInflammation

FREE RADICAL BIOLOGY AND MEDICINE, 134, 598–603.

By: A. Pecorelli n, C. Cervellati*, V. Cordone n, F. Amicarelli*, J. Hayek* & G. Valacchi n

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: Rett syndrome; Oxidative stress; Hydroxyoctadecadienoic acids; Inflammation; Omega-3 polyunsaturated fatty acids; Arachidonate 15-Lipoxygenase
MeSH headings : Adolescent; Adult; Arachidonate 15-Lipoxygenase / genetics; Arachidonate 15-Lipoxygenase / metabolism; Case-Control Studies; Child; Female; Humans; Inflammation / genetics; Inflammation / metabolism; Inflammation / pathology; Leukocytes, Mononuclear / metabolism; Linoleic Acids / metabolism; Linoleic Acids, Conjugated / metabolism; Male; Rett Syndrome / genetics; Rett Syndrome / metabolism; Rett Syndrome / pathology; Young Adult
Sources: Web Of Science, ORCID
Added: July 1, 2019

2019 journal article

Antiglycative Activity and RAGE Expression in Rett Syndrome

CELLS, 8(2).

By: V. Cordone*, A. Pecorelli n, M. Benedusi*, S. Santini*, S. Falone*, J. Hayek*, F. Amicarelli*, G. Valacchi n

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: methylglyoxal; glyoxalases; advanced glycation end products; MeCP2; dicarbonyl stress; fibroblasts
MeSH headings : Adolescent; Adult; Antigens, Neoplasm / metabolism; Cell Survival / drug effects; Child; Female; Fibroblasts / drug effects; Fibroblasts / metabolism; Glycosylation; Humans; Lactoylglutathione Lyase / metabolism; Mitogen-Activated Protein Kinases / metabolism; Pyruvaldehyde / pharmacology; Rett Syndrome / metabolism; Rett Syndrome / pathology; Thiolester Hydrolases / metabolism; Young Adult
Sources: Web Of Science, ORCID
Added: March 25, 2019

2019 article

Blueberries Topical Application Prevents Ozone Induced Cutaneous Inflammasome Activation

Pambianchi, E., Francesca, F., Pecorelli, A., Woodby, B., Lila, M., & Valacchi, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S148–S148.

By: E. Pambianchi, F. Francesca, A. Pecorelli, B. Woodby, M. Lila & G. Valacchi

Sources: Web Of Science, ORCID
Added: December 2, 2019

2019 journal article

Bone status in relation to ambulatory performance in girls with Rett syndrome: a 10-year longitudinal study

PEDIATRIC RESEARCH, 85(5), 639–643.

By: C. Caffarelli*, V. Francolini n, J. Hayek*, G. Valacchi*, S. Giannotti*, R. Nuti*, S. Gonnelli*

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
MeSH headings : Absorptiometry, Photon; Adolescent; Bone Density; Bone and Bones / diagnostic imaging; Bone and Bones / physiology; Child; Child Nutrition Sciences; Child, Preschool; Cholecalciferol / administration & dosage; Disabled Persons; Female; Finger Phalanges / diagnostic imaging; Follow-Up Studies; Fractures, Bone / diagnostic imaging; Humans; Infant; Longitudinal Studies; Nutritional Status; Rett Syndrome / diagnostic imaging; Rett Syndrome / physiopathology; Surveys and Questionnaires; Ultrasonography; Vitamin D / blood; Walking
Sources: Web Of Science, ORCID
Added: April 9, 2019

2019 article

Comparing Skin Aging in Vitro Induced by External and Internal Cigarette Smoke Exposure

Prieux, R., Valacchi, G., Benedusi, M., & Cervellati, F. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S137–S137.

By: R. Prieux, G. Valacchi, M. Benedusi & F. Cervellati

Sources: Web Of Science, ORCID
Added: December 2, 2019

2019 journal article

Conjugation of LasR Quorum-Sensing Inhibitors with Ciprofloxacin Decreases the Antibiotic Tolerance of P-aeruginosa Clinical Strains

JOURNAL OF CHEMISTRY, 2019.

By: D. Bortolotti*, C. Trapella*, A. Bragonzi*, P. Marchetti*, V. Zanirato*, A. Alogna*, V. Gentili*, C. Cervellati* ...

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: April 9, 2019

2019 journal article

Development of novel multipotent compounds modulating endocannabinoid and dopaminergic systems

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 183.

By: A. Grillo*, G. Chemi*, S. Brogi*, M. Brindisi*, N. Relitti*, F. Fezza*, D. Fazio*, L. Castelletti* ...

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: Endocannabinoid system; Fatty acid amide hydrolase; Enzyme inhibitors; Selective inhibitors; Dopamine ligands; Polypharmacology; Multitarget compounds; Dopamine receptor ligands
MeSH headings : Amidohydrolases / antagonists & inhibitors; Amidohydrolases / metabolism; Binding, Competitive; Cell Line; Cell Survival / drug effects; Dopamine / metabolism; Endocannabinoids / metabolism; Enzyme Inhibitors / chemistry; Enzyme Inhibitors / pharmacology; Humans; Ligands; Piperazines / chemistry; Piperazines / pharmacology; Pyrroles / chemistry; Pyrroles / pharmacology
Sources: Web Of Science, ORCID
Added: December 16, 2019

2019 review

Evaluating the link between Paraoxonase-1 levels and Alzheimer's disease development

[Review of ]. MINERVA MEDICA, 110(3), 238–250.

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: PON1 protein, human; Alzheimer's disease; Oxidative stress
MeSH headings : Alzheimer Disease / blood; Alzheimer Disease / epidemiology; Alzheimer Disease / etiology; Aryldialkylphosphatase / blood; Humans
Sources: Web Of Science, ORCID
Added: May 6, 2019

2019 article

HGA Induces Oxidative Damage in an Ostcoblastic Cellular Model of Alkaptonuria: Sources and Mechanisms HGA Induces Oxidative Damage in an Osteoblastic Cellular Model of Alkaptonuria: Sources and Mechanisms

Schiavone, M. L., Pecorelli, A., Woodby, B., Ferrara, F., Santucci, A., & Valacchi, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S37–S38.

By: M. Schiavone, A. Pecorelli, B. Woodby, F. Ferrara, A. Santucci & G. Valacchi

Sources: Web Of Science, ORCID
Added: December 2, 2019

2019 review

Involvement of 4-hydroxy-2-nonenal in pollution-induced skin damage

[Review of ]. BIOFACTORS, 45(4), 536–547.

By: A. Pecorelli n, B. Woodby n, R. Prieux* & G. Valacchi n

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: ozone; particulate matter; cigarette smoke; peroxidation
MeSH headings : Air Pollutants / metabolism; Air Pollutants / toxicity; Aldehydes / metabolism; Aldehydes / toxicity; Dermatitis, Atopic / chemically induced; Dermatitis, Atopic / genetics; Dermatitis, Atopic / metabolism; Dermatitis, Atopic / pathology; Gene Expression Regulation / drug effects; Humans; Mitogen-Activated Protein Kinases / genetics; Mitogen-Activated Protein Kinases / metabolism; Oxidation-Reduction; Oxidative Stress; Ozone / metabolism; Ozone / toxicity; Particulate Matter / toxicity; Psoriasis / chemically induced; Psoriasis / genetics; Psoriasis / metabolism; Psoriasis / pathology; Reactive Oxygen Species / agonists; Reactive Oxygen Species / metabolism; Signal Transduction; Skin / drug effects; Skin / metabolism; Skin / pathology; Skin Aging / drug effects; Skin Aging / genetics; Skin Aging / pathology; Tobacco Smoke Pollution / adverse effects; Transcription Factors / genetics; Transcription Factors / metabolism
Sources: Web Of Science, ORCID
Added: April 20, 2020

2019 journal article

Involvement of cutaneous SR-B1 in skin lipid homeostasis

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 666, 1–7.

By: X. Muresan*, M. Narzt*, B. Woodby n, F. Ferrara n, F. Gruber & G. Valacchi n

co-author countries: Austria 🇦🇹 Italy 🇮🇹 United States of America 🇺🇸
author keywords: Scavenger receptor; Skin; Keratinocytes; Lipids; Ceramides; Cholesterol; Differentiation
MeSH headings : Cell Differentiation / physiology; Cells, Cultured; Filaggrin Proteins; Gene Expression Regulation; Homeostasis; Humans; Keratinocytes / cytology; Lipid Metabolism / genetics; Scavenger Receptors, Class B / genetics; Scavenger Receptors, Class B / physiology; Skin / cytology; Skin / metabolism
Sources: Web Of Science, ORCID
Added: June 17, 2019

2019 journal article

Involvement of the TREK-1 channel in human alveolar cell membrane potential and its regulation by inhibitors of the chloride current

JOURNAL OF CELLULAR PHYSIOLOGY, 234(10), 17704–17713.

By: R. Canella*, M. Martini*, C. Cavicchio, F. Cervellati*, M. Benedusi* & G. Valacchi*

co-author countries: Italy 🇮🇹
author keywords: 9-AC; A549 cells; ANO-6; DCPIB; K plus channels; pneumocytes
MeSH headings : A549 Cells; Alveolar Epithelial Cells / metabolism; Biological Transport / physiology; Cell Line, Tumor; Cell Membrane / metabolism; Cell Size; Chloride Channels / metabolism; Chlorides / metabolism; Humans; Membrane Potentials / physiology; Patch-Clamp Techniques / methods; Potassium Channels, Tandem Pore Domain / metabolism
Sources: Web Of Science, ORCID
Added: July 29, 2019

2019 journal article

Lipid nanostructures for antioxidant delivery: a comparative preformulation study

BEILSTEIN JOURNAL OF NANOTECHNOLOGY, 10, 1789–1801.

By: E. Esposito, M. Sguizzato, M. Drechsler, P. Mariani, F. Carducci, C. Nastruzzi, G. Valacchi*, R. Cortesi

author keywords: alpha-tocopherol; cryogenic transmission electron microscopy (cryo-TEM); dermocosmetics; HO-1; nanostructured lipid carriers (NLCs); retinoic acid; skin pollution; solid lipid nanoparticles (SLNs)
Sources: Web Of Science, ORCID
Added: September 16, 2019

2019 journal article

Multiple mechanisms of Rottlerin toxicity in A375 melanoma cells

BIOFACTORS, 45(6), 920–929.

By: F. Ietta*, G. Valacchi*, L. Benincasa*, A. Pecorelli*, L. Cresti* & E. Maioli*

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷
author keywords: apoptosis; ER stress; melanoma; mitochondria; protein synthesis; rottlerin
Sources: Web Of Science, ORCID
Added: August 26, 2019

2019 article

OxInflammation as a Aossible new Player in Rett Syndrome Pathophysiology

Pecorelli, A., Valacchi, G., Cordone, V., & Hayek, J. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S149–S149.

By: A. Pecorelli, G. Valacchi, V. Cordone & J. Hayek

Sources: Web Of Science, ORCID
Added: December 2, 2019

2019 review

Ozonated Oils and Cutaneous Wound Healing

[Review of ]. CURRENT PHARMACEUTICAL DESIGN, 25(20), 2264–2278.

By: Y. Lim*, H. Lee*, B. Woodby n & G. Valacchi*

co-author countries: Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: Cutaneous wound healing; ROS; peroxidation; topical application; ozonated oil; inflammation
MeSH headings : Humans; Ozone; Phytotherapy; Plant Oils / therapeutic use; Skin; Wound Healing
Sources: Web Of Science, ORCID
Added: October 7, 2019

2019 article

Redox Regulation of Cutaneous Inflammasome Pathway by Ozone Exposure

Ferrara, F., Pecorelli, A., Woodby, B., Pambianchi, E., Messano, N., Therrien, J. P., & Valacchi, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S22–S23.

By: F. Ferrara, A. Pecorelli, B. Woodby, E. Pambianchi, N. Messano, J. Therrien, G. Valacchi

Sources: Web Of Science, ORCID
Added: December 2, 2019

2019 article

Redox Regulation of Cutaneous Inflammasome Pathway by Ozone Exposure

FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S22–S23.

By: F. Ferrara, A. Pecorelli, B. Woodby, E. Pambianchi, N. Messano, J. Therrien, G. Valacchi

Source: ORCID
Added: December 3, 2019

2019 article

Redox-Regulation of Antimicrobial Peptides

Woodby, B., Pambianchi, E., Francesca, F., Messano, N., Pecorelli, A., Therrien, J. P., & Valacchii, G. (2019, December). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 145, pp. S54–S55.

By: B. Woodby, E. Pambianchi, F. Francesca, N. Messano, A. Pecorelli, J. Therrien, G. Valacchii

Sources: Web Of Science, ORCID
Added: December 2, 2019

2019 journal article

Skin damage by tropospheric ozone

HAUTARZT, 70(3), 163–168.

By: K. Fuks*, B. Woodby n & G. Valacchi n

co-author countries: Germany 🇩🇪 Italy 🇮🇹 United States of America 🇺🇸
author keywords: Air pollution; Skin aging; Skin wrinkling; Oxidative stress; Peroxidation
MeSH headings : Air Pollutants / adverse effects; Air Pollution; Humans; Lipid Peroxidation / drug effects; Nitrogen Dioxide / analysis; Oxidative Stress; Ozone / adverse effects; Ozone / analysis; Particulate Matter / analysis; Public Health; Skin Aging / drug effects; Skin Aging / radiation effects; Ultraviolet Rays / adverse effects
Sources: Web Of Science, ORCID
Added: March 25, 2019

2019 journal article

Trehalose inhibits cell proliferation and amplifies long-term temozolomide- and radiation-induced cytotoxicity in melanoma cells: A role for autophagy and premature senescence

JOURNAL OF CELLULAR PHYSIOLOGY, 234(7), 11708–11721.

By: G. Allavena*, B. Del Bello*, P. Tini*, N. Volpi*, G. Valacchi*, C. Miracco*, L. Pirtoli*, E. Maellaro*

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: melanoma cells; trehalose; autophagy; premature senescence; radiosensitization
MeSH headings : Apoptosis / drug effects; Apoptosis / radiation effects; Autophagy / drug effects; Autophagy / radiation effects; Cell Line, Tumor; Cell Proliferation / drug effects; Cell Proliferation / radiation effects; Cellular Senescence / drug effects; Cellular Senescence / radiation effects; Chloroquine / pharmacology; Drug Resistance, Neoplasm / drug effects; Humans; Melanocytes / drug effects; Melanocytes / metabolism; Melanocytes / pathology; Melanocytes / radiation effects; Melanoma / pathology; Melanoma / radiotherapy; Radiation, Ionizing; Sequestosome-1 Protein / metabolism; Temozolomide / pharmacology; Trehalose / pharmacology
Sources: Web Of Science, ORCID
Added: April 22, 2019

2018 article

AtmO(3)spheric skin damage: The oxInflammation phenomena

Valacchi, G., Pecorelli, A., Pambianchi, E., Ferrara, F., & Lila, M. (2018, September). JOURNAL OF INVESTIGATIVE DERMATOLOGY, Vol. 138, pp. B15–B15.

By: G. Valacchi n, A. Pecorelli*, E. Pambianchi*, F. Ferrara n & M. Lila*

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: October 19, 2018

2018 journal article

Circadian clock as possible protective mechanism to pollution induced keratinocytes damage

Mechanisms of Ageing and Development, 172, 13–20.

By: M. Benedusi*, E. Frigato*, M. Beltramello*, C. Bertolucci* & G. Valacchi*

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: Ozone (O-3); Oxidative stress; Circadian clock; Antioxidant pathway; Skin homeostasis
MeSH headings : ARNTL Transcription Factors / metabolism; Air Pollutants / toxicity; Cell Line; Circadian Clocks; Gene Expression Regulation / drug effects; Humans; Keratinocytes / metabolism; Keratinocytes / pathology; NF-E2-Related Factor 2 / metabolism; Organ Specificity; Ozone / toxicity; Skin / metabolism; Skin / pathology
Sources: Crossref, ORCID
Added: January 25, 2020

2018 journal article

Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain

ChemMedChem, 13(19), 2090–2103.

By: M. Brindisi*, G. Borrelli*, S. Brogi*, A. Grillo*, S. Maramai*, M. Paolino*, M. Benedusi*, A. Pecorelli n ...

co-author countries: Canada 🇨🇦 Italy 🇮🇹 United States of America 🇺🇸
author keywords: covalent inhibitors; endocannabinoid system; fatty acid amide hydrolase; neuropathic pain; serine hydrolase
MeSH headings : Amidohydrolases / antagonists & inhibitors; Animals; Benzodiazepinones / chemical synthesis; Benzodiazepinones / pharmacology; Benzodiazepinones / therapeutic use; Benzodiazepinones / toxicity; Cell Line, Tumor; Enzyme Inhibitors / chemical synthesis; Enzyme Inhibitors / pharmacology; Enzyme Inhibitors / therapeutic use; Enzyme Inhibitors / toxicity; Humans; Male; Mice; Molecular Docking Simulation; Molecular Structure; NF-kappa B / metabolism; Neuralgia / drug therapy; Oxidative Stress / drug effects; Structure-Activity Relationship
Sources: Crossref, ORCID
Added: January 25, 2020

2018 article

Inflammasome involvement in Rett syndrome subclinical inflammation

Pecorelli, A., Cordone, V., Falone, S., Romani, A., Benedusi, M., Hayek, J., … Valacchi, G. (2018, November 20). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 128, pp. S108–S109.

By: A. Pecorelli n, V. Cordone*, S. Falone*, A. Romani*, M. Benedusi*, J. Hayek*, F. Amicarelli*, G. Valacchi n

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: November 19, 2018

2018 journal article

Keratinocytes oxidative damage mechanisms related to airbone particle matter exposure

MECHANISMS OF AGEING AND DEVELOPMENT, 172, 86–95.

By: A. Romani*, C. Cervellati*, X. Muresan*, G. Belmonte*, A. Pecorelli n, F. Cervellati*, M. Benedusi*, P. Evelson*, G. Valacchi n

co-author countries: Argentina 🇦🇷 Italy 🇮🇹 United States of America 🇺🇸
author keywords: Air pollution; Particulate matter; Oxidative damage; Inflammation
MeSH headings : Cell Line, Transformed; Humans; Interleukin-1alpha / metabolism; Keratinocytes / metabolism; Keratinocytes / pathology; NF-E2-Related Factor 2 / metabolism; NF-kappa B / metabolism; Oxidation-Reduction / drug effects; Particulate Matter / toxicity
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Lifestyle determinants of healthy ageing in a Mediterranean population: The multinational MEDIS study

Experimental Gerontology, 110, 35–41.

By: A. Foscolou*, E. Magriplis*, S. Tyrovolas*, G. Soulis*, V. Bountziouka*, A. Mariolis, S. Piscopo*, G. Valacchi* ...

co-author countries: Spain 🇪🇸 Greece 🇬🇷 Italy 🇮🇹 Malta 🇲🇹 United States of America 🇺🇸
author keywords: Healthy ageing; Longevity; Elderly; Health policy; Mediterranean
MeSH headings : Aged; Aged, 80 and over; Cardiovascular Diseases / epidemiology; Diet, Mediterranean; Exercise; Feeding Behavior; Female; Healthy Aging; Humans; Logistic Models; Longevity; Male; Mediterranean Region / epidemiology; Risk Factors; Smoking / epidemiology
Sources: Crossref, ORCID
Added: January 25, 2020

2018 journal article

Low-grade systemic inflammation is associated with functional disability in elderly people affected by dementia

GeroScience, 40(1), 61–69.

co-author countries: Italy 🇮🇹
author keywords: Inflammation; Dementia; Alzheimer's disease; Mixed dementia; Functional abilities
MeSH headings : Activities of Daily Living; Aged; Aged, 80 and over; Aging / physiology; Alzheimer Disease / etiology; Alzheimer Disease / physiopathology; Analysis of Variance; C-Reactive Protein / metabolism; Case-Control Studies; Cognitive Dysfunction / etiology; Cognitive Dysfunction / physiopathology; Dementia / complications; Dementia / diagnosis; Disability Evaluation; Disease Progression; Female; Geriatric Assessment / methods; Homocysteine / metabolism; Humans; Inflammation / complications; Inflammation / diagnosis; Italy; Male; Reference Values; Retrospective Studies
Sources: Crossref, ORCID
Added: January 25, 2020

2018 journal article

Mediterranean diet and depression among older individuals: The multinational MEDIS study

Experimental Gerontology, 110, 67–72.

By: M. Masana*, J. Haro*, A. Mariolis, S. Piscopo*, G. Valacchi*, V. Bountziouka*, F. Anastasiou*, A. Zeimbekis ...

co-author countries: Spain 🇪🇸 Greece 🇬🇷 Italy 🇮🇹 Malta 🇲🇹 United States of America 🇺🇸
author keywords: Mediterranean diet; Tea; Depression; Older adults
MeSH headings : Aged; Aged, 80 and over; Cross-Sectional Studies; Depression / epidemiology; Diet, Mediterranean; Female; Geriatric Assessment; Humans; Life Style; Logistic Models; Male; Mediterranean Region / epidemiology; Psychiatric Status Rating Scales; Risk Factors; Self Report; Tea
Sources: Crossref, ORCID
Added: January 25, 2020

2018 journal article

Modulation of cutaneous scavenger receptor B1 levels by exogenous stressors impairs “in vitro” wound closure

Mechanisms of Ageing and Development, 172, 78–85.

By: X. Muresan*, C. Sticozzi*, G. Belmonte*, V. Savelli*, P. Evelson* & G. Valacchi n

co-author countries: Argentina 🇦🇷 Italy 🇮🇹 United States of America 🇺🇸
author keywords: Skin; Oxidative stress; Pollution; RHE; Wound healing; Particulate matter; Cigarette smoke; Ozone
MeSH headings : Cell Line, Transformed; Epidermis / metabolism; Epidermis / pathology; Gene Expression Regulation; Humans; Keratinocytes / metabolism; Keratinocytes / pathology; Scavenger Receptors, Class B / biosynthesis; Tobacco Smoke Pollution / adverse effects; Wound Healing
Sources: Crossref, ORCID
Added: January 25, 2020

2018 journal article

Non-conventional rottlerin anticancer properties

Archives of Biochemistry and Biophysics, 645, 50–53.

By: E. Maioli*, E. Daveri*, E. Maellaro*, F. Ietta*, L. Cresti* & G. Valacchi*

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
MeSH headings : Acetophenones / pharmacology; Acetophenones / therapeutic use; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Benzopyrans / pharmacology; Benzopyrans / therapeutic use; Breast Neoplasms / drug therapy; Humans; Melanoma / drug therapy
Sources: Crossref, ORCID
Added: January 25, 2020

2018 journal article

OXINFLAMMATION IN RETT SYNDROME

Pathophysiology, 25(3), 189.

By: G. Valacchi n, A. Pecorelli n & C. Cervellati*

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
Sources: Crossref, ORCID
Added: January 25, 2020

2018 review

OxInflammation: From Subclinical Condition to Pathological Biomarker

[Review of ]. FRONTIERS IN PHYSIOLOGY, 9.

By: G. Valacchi n, F. Virgili*, C. Cervellati* & A. Pecorelli n

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: biomarkers; neurological disorders; oxidative stress; inflammation mediators; NF kappa B
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Role of Nrf2 in preventing oxidative stress induced chloride current alteration in human lung cells

Journal of Cellular Physiology, 233(8), 6018–6027.

By: R. Canella*, M. Benedusi*, M. Martini*, F. Cervellati*, C. Cavicchio* & G. Valacchi*

co-author countries: Italy 🇮🇹
author keywords: catalase; chloride current; ozone; patch clamp; redox imbalance; respiratory tract
MeSH headings : A549 Cells; Antioxidants / metabolism; Catalase / metabolism; Cell Line, Tumor; Cell Survival / drug effects; Cell Survival / physiology; Chloride Channels / metabolism; Chlorides / metabolism; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Gene Expression Regulation / drug effects; Gene Expression Regulation / physiology; Humans; Hydrogen Peroxide / pharmacology; Lung / drug effects; Lung / metabolism; NF-E2-Related Factor 2 / metabolism; Oxidative Stress / drug effects; Oxidative Stress / physiology; Ozone / pharmacology
Sources: Crossref, ORCID
Added: January 25, 2020

2018 journal article

SR-B1 involvement in keratinocytes in vitro wound closure

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 658, 1–6.

By: X. Muresan*, C. Sticozzi*, G. Belmonte*, F. Cervellati*, F. Ferrara*, M. Lila n, G. Valacchi n

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: Wound healing; Skin; Proliferation; Migration
MeSH headings : Cell Line, Transformed; Cell Movement / physiology; Cell Proliferation / physiology; Cyclin D1 / metabolism; Gene Knockout Techniques; Humans; Keratinocytes / cytology; Keratinocytes / physiology; Matrix Metalloproteinase 9 / metabolism; NF-kappa B p50 Subunit / metabolism; Scavenger Receptors, Class B / genetics; Scavenger Receptors, Class B / physiology; Skin / metabolism; Wound Healing / physiology
Sources: Web Of Science, ORCID
Added: November 26, 2018

2018 article

Scavenger receptor B1 as a possible new player in cutaneous tissue proliferation and differentiation

Valacchi, G., Muresan, X., Belmonte, G., Pecorelli, A., & Gruber, F. (2018, September). JOURNAL OF INVESTIGATIVE DERMATOLOGY, Vol. 138, pp. B25–B25.

By: G. Valacchi n, X. Muresan, G. Belmonte*, A. Pecorelli & F. Gruber

co-author countries: Austria 🇦🇹 Italy 🇮🇹 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: October 19, 2018

2018 journal article

Tropospheric ozone affects SRB1 levels via oxidative post-translational modifications in lung cells

FREE RADICAL BIOLOGY AND MEDICINE, 126, 287–295.

By: C. Sticozzi*, A. Pecorelli*, A. Romani*, G. Belmonte*, F. Cervellati*, E. Maioli*, M. Lila*, C. Gervellati, G. Valacchi*

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
MeSH headings : A549 Cells; Aldehydes / metabolism; Alveolar Epithelial Cells / drug effects; Alveolar Epithelial Cells / metabolism; Antioxidants / pharmacology; Biological Transport / drug effects; Catalase / genetics; Catalase / metabolism; Cell Survival / drug effects; Humans; Hydrogen Peroxide / metabolism; Lung / drug effects; Lung / metabolism; Lung / pathology; Oxidation-Reduction / drug effects; Oxidative Stress / drug effects; Ozone / pharmacology; Protein Processing, Post-Translational / drug effects; Scavenger Receptors, Class B / genetics; Scavenger Receptors, Class B / metabolism; Vitamin E / metabolism
Sources: Web Of Science, ORCID
Added: October 16, 2018

2017 review

4-hydroxynonenal protein adducts: Key mediator in Rett syndrome oxinflammation

[Review of ]. FREE RADICAL BIOLOGY AND MEDICINE, 111, 270–280.

By: G. Valacchi n, A. Pecorelli n, C. Cervellati* & J. Hayek*

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: Inflammation; Isoprostanes; Oxidative stress; Rare disease; Orphan disease; CDKL5; FOXG1; MecP2
MeSH headings : Aldehydes / metabolism; Brain / metabolism; Brain / pathology; Feedback, Physiological; Forkhead Transcription Factors / genetics; Forkhead Transcription Factors / metabolism; Humans; Inflammation; Isoprostanes / metabolism; Lipid Peroxidation / genetics; Methyl-CpG-Binding Protein 2 / genetics; Methyl-CpG-Binding Protein 2 / metabolism; Mutation; Nerve Tissue Proteins / genetics; Nerve Tissue Proteins / metabolism; Oxidative Stress; Proteasome Endopeptidase Complex / metabolism; Protein Processing, Post-Translational; Protein Serine-Threonine Kinases / genetics; Protein Serine-Threonine Kinases / metabolism; Rett Syndrome / genetics; Rett Syndrome / metabolism; Rett Syndrome / pathology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

First dual AK/GSK-3 beta inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 138, 438–457.

By: S. Brogi*, A. Ramunno*, L. Savi*, G. Chemi*, G. Alfano*, A. Pecorelli n, E. Pambianchi n, P. Galatello* ...

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: Antioxidant agents; Glycogen synthase kinase 3 beta (GSK-3 beta); Adenosine kinase (AK); Dual inhibitors; Molecular docking
MeSH headings : Adenosine Kinase / antagonists & inhibitors; Adenosine Kinase / metabolism; Antioxidants / chemical synthesis; Antioxidants / chemistry; Antioxidants / pharmacology; Cell Line, Tumor; Dose-Response Relationship, Drug; Glycogen Synthase Kinase 3 beta / antagonists & inhibitors; Glycogen Synthase Kinase 3 beta / metabolism; Humans; Hydrogen Peroxide / antagonists & inhibitors; Hydrogen Peroxide / pharmacology; Molecular Structure; Neuroblastoma / metabolism; Neuroblastoma / pathology; Neuroprotective Agents / chemical synthesis; Neuroprotective Agents / chemistry; Neuroprotective Agents / pharmacology; Oxidative Stress / drug effects; Protein Kinase Inhibitors / chemical synthesis; Protein Kinase Inhibitors / chemistry; Protein Kinase Inhibitors / pharmacology; Reactive Oxygen Species / metabolism; Structure-Activity Relationship
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Is car use related with successful aging of older adults? Results from the multinational Mediterranean islands study

Annals of Epidemiology, 27(3), 225–229.

By: S. Tyrovolas*, E. Polychronopoulos*, M. Morena*, A. Mariolis, S. Piscopo*, G. Valacchi*, V. Bountziouka*, F. Anastasiou* ...

co-author countries: Spain 🇪🇸 Greece 🇬🇷 Italy 🇮🇹 Malta 🇲🇹 United States of America 🇺🇸
author keywords: Successful aging; Car use; Driving; Mediterranean islands; Older adults
MeSH headings : Aged; Aged, 80 and over; Aging / physiology; Aging / psychology; Automobile Driving / psychology; Automobile Driving / statistics & numerical data; Cross-Sectional Studies; Female; Greece; Humans; Male; Mediterranean Islands; Quality of Life / psychology; Rural Population / statistics & numerical data
Sources: Crossref, ORCID
Added: January 25, 2020

2017 journal article

Mediterranean lifestyle and cardiovascular disease prevention

Cardiovascular Diagnosis and Therapy, 7, S39–47.

By: E. Georgousopoulou, D. Mellor, N. Naumovski, E. Polychronopoulos, S. Tyrovolas, S. Piscopo, G. Valacchi, F. Anastasiou ...

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Modulation of Chloride Currents in Human Lung Epithelial Cells Exposed to Exogenous Oxidative Stress

JOURNAL OF CELLULAR PHYSIOLOGY, 232(7), 1817–1825.

By: R. Canella*, M. Martini*, R. Borriello*, C. Cavicchio*, X. Muresan*, M. Benedusi*, F. Cervellati*, G. Valacchi n

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
MeSH headings : A549 Cells; Chloride Channels / metabolism; Electrophysiological Phenomena / drug effects; Epithelial Cells / drug effects; Epithelial Cells / metabolism; Humans; Lung / pathology; Oxidative Stress / drug effects; Ozone / pharmacology; Patch-Clamp Techniques; Protective Agents / pharmacology; Vitamin E / pharmacology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Monoolein aqueous dispersions as a delivery system for quercetin

Biomedical Microdevices, 19(2).

By: R. Cortesi*, E. Cappellozza*, M. Drechsler*, C. Contado*, A. Baldisserotto*, P. Mariani*, F. Carducci*, A. Pecorelli, E. Esposito*, G. Valacchi*

co-author countries: Germany 🇩🇪 Italy 🇮🇹
author keywords: Quercetin; Monoolein aqueous dispersions (MAD); Monoolein; Antioxidant activity
MeSH headings : Antioxidants / chemistry; Antioxidants / toxicity; Cell Line; Drug Carriers / chemistry; Glycerides / chemistry; Humans; Kinetics; Quercetin / chemistry; Quercetin / toxicity; Water / chemistry
Sources: Crossref, ORCID
Added: January 25, 2020

2017 journal article

Nanostructured lipid carriers (NLC) for the delivery of natural molecules with antimicrobial activity: production, characterisation and in vitro studies

Journal of Microencapsulation, 34(1), 63–72.

co-author countries: Germany 🇩🇪 Italy 🇮🇹 United States of America 🇺🇸
author keywords: Nanoparticles; nanotechnology; formulation; nanostructured lipid carriers
MeSH headings : Anti-Infective Agents / administration & dosage; Anti-Infective Agents / pharmacology; Bacteria / drug effects; Bacterial Infections / drug therapy; Cell Line; Cyanobacteria / drug effects; Drug Carriers / chemistry; Fungi / drug effects; Humans; Lipids / chemistry; Mycoses / drug therapy; Nanostructures / chemistry; Nanostructures / ultrastructure
Sources: Crossref, ORCID
Added: January 25, 2020

2017 journal article

Nanostructured lipid systems modified with waste material of propolis for wound healing: Design, in vitro and in vivo evaluation

Colloids and Surfaces B: Biointerfaces, 158, 441–452.

By: H. Rosseto*, L. Toledo*, L. Francisco*, E. Esposito*, Y. Lim*, G. Valacchi*, R. Cortesi*, M. Bruschi*

co-author countries: Brazil 🇧🇷 Italy 🇮🇹 Korea (Republic of) 🇰🇷
author keywords: Nanotechnology; Materials science; Formulation; Propolis by-product; Nanoparticles; Nanostructured lipid carriers; Propolis byproduct
MeSH headings : Drug Delivery Systems / methods; Lipids / chemistry; Nanoparticles / chemistry; Nanostructures / chemistry; Nanotechnology / methods; Propolis / chemistry; Wound Healing / physiology
Sources: Crossref, ORCID
Added: January 25, 2020

2017 journal article

Novel Artificial Tears Containing Cross-Linked Hyaluronic Acid: An In Vitro Re-Epithelialization Study

MOLECULES, 22(12).

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: anti-inflammatory; artificial tears; corneal epithelium; cyclin D1; dry eye syndrome; HA; HA-CL; IL-8; re-epithelialization
MeSH headings : Analysis of Variance; Biomarkers; Cell Line; Cell Survival; Cyclin D1 / metabolism; Drug Stability; Dry Eye Syndromes; Epithelium, Corneal / drug effects; Humans; Hyaluronic Acid / analysis; Hyaluronic Acid / chemistry; Hydrogen-Ion Concentration; Lubricant Eye Drops / analysis; Lubricant Eye Drops / chemical synthesis; Lubricant Eye Drops / chemistry; Lubricant Eye Drops / pharmacology; Re-Epithelialization / drug effects; Viscosity; Wound Healing / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Paraoxonase, arylesterase and lactonase activities of paraoxonase-1 (PON1) in obese and severely obese women

Scandinavian Journal of Clinical and Laboratory Investigation, 78(1-2), 18–24.

By: C. Cervellati*, G. Bonaccorsi*, A. Trentini*, G. Valacchi*, J. Sanz*, M. Squerzanti*, M. Spagnolo*, L. Massari* ...

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
author keywords: Arylesterase; body mass index; markers of oxidative stress; obesity; paraoxonase-1
MeSH headings : Anthropometry; Aryldialkylphosphatase / blood; Body Mass Index; Carboxylic Ester Hydrolases / blood; Female; Humans; Middle Aged; Obesity / blood; Obesity / enzymology; Regression Analysis
Sources: Crossref, ORCID
Added: January 25, 2020

2017 journal article

Potassium Ascorbate with Ribose: Promising Therapeutic Approach for Melanoma Treatment

OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2017.

By: C. Cavicchio*, M. Benedusi*, E. Pambianchi n, A. Pecorelli n, F. Cervellati*, V. Savelli*, D. Calamandrei*, E. Maellaro* ...

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Antineoplastic Agents / therapeutic use; Ascorbic Acid / chemistry; Cell Line, Tumor; Cell Proliferation / drug effects; Cell Survival / drug effects; Connexin 43 / genetics; Connexin 43 / metabolism; Humans; Melanoma / drug therapy; Melanoma / pathology; Microscopy, Electron, Scanning; Potassium / chemistry; Ribose / chemistry; Spheroids, Cellular / drug effects; Spheroids, Cellular / ultrastructure
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Protective Effects of Topical Vitamin C Compound Mixtures against Ozone-Induced Damage in Human Skin

Journal of Investigative Dermatology, 137(6), 1373–1375.

By: G. Valacchi*, A. Pecorelli*, G. Belmonte, E. Pambianchi, F. Cervellati, S. Lynch*, Y. Krol*, C. Oresajo*

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
MeSH headings : Administration, Topical; Antioxidants / therapeutic use; Ascorbic Acid / therapeutic use; Biopsy, Needle; Dermatitis / drug therapy; Dermatitis / etiology; Dermatitis / pathology; Environmental Exposure / adverse effects; Female; Humans; Immunohistochemistry; Male; Oxidative Stress / drug effects; Ozone / adverse effects; Reference Values; Risk Assessment; Treatment Outcome
Sources: Crossref, ORCID
Added: January 25, 2020

2017 journal article

Resveratrol: from diet to topical usage

Food & Function, 8(11), 3879–3892.

By: V. Chedea*, S. Vicaş, C. Sticozzi*, F. Pessina*, M. Frosini*, E. Maioli*, G. Valacchi*

co-author countries: Italy 🇮🇹 Romania 🇷🇴 United States of America 🇺🇸
MeSH headings : Animals; Cardiovascular Diseases / prevention & control; Cosmetics / analysis; Humans; Resveratrol; Skin / drug effects; Skin / metabolism; Stilbenes / metabolism; Stilbenes / pharmacology
Sources: Crossref, ORCID
Added: January 25, 2020

2017 journal article

Retention of mitochondria in mature human red blood cells as the result of autophagy impairment in Rett syndrome

Scientific Reports, 7.

By: D. Sbardella*, G. Tundo*, L. Campagnolo*, G. Valacchi n, A. Orlandi*, P. Curatolo*, G. Borsellino*, M. D'Esposito* ...

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
MeSH headings : Animals; Autophagosomes / pathology; Autophagy / genetics; Cells, Cultured; Cerebellum / pathology; Disease Models, Animal; Erythrocytes / cytology; Erythrocytes / metabolism; Erythrocytes / ultrastructure; Female; Fibroblasts; Healthy Volunteers; Humans; Male; Methyl-CpG-Binding Protein 2 / genetics; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mutation; Primary Cell Culture; Protein Aggregates / genetics; Rett Syndrome / blood; Rett Syndrome / genetics; Rett Syndrome / pathology; Sequestosome-1 Protein / metabolism
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2017 article

Serum from patients affected by Alzheimer disease shows a paraoxonase-dependent pro-apoptotic effect on endothelial cells

Crivellari, I., Cervellati, C., Dalla Sega, F. V., Valacchi, G., Trentini, A., Passaro, A., … Rizzo, P. (2017, July). FREE RADICAL BIOLOGY AND MEDICINE, Vol. 108, pp. S93–S93.

By: I. Crivellari*, C. Cervellati*, F. Dalla Sega*, G. Valacchi n, A. Trentini*, A. Passaro*, C. Bosi*, A. Romani* ...

co-author countries: Italy 🇮🇹 United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Abnormal N-glycosylation pattern for brain nucleotide pyrophosphatase-5 (NPP-5) in Mecp2-mutant murine models of Rett syndrome

Neuroscience Research, 105, 28–34.

By: A. Cortelazzo*, C. De Felice*, R. Guerranti*, C. Signorini*, S. Leoncini*, A. Pecorelli*, F. Scalabrì*, M. Madonna* ...

co-author countries: France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Italy 🇮🇹
author keywords: Protein glycosylation; Neurological disorders; Nucleotide pyrophosphatase; Mecp2
MeSH headings : Animals; Brain / metabolism; Glycosylation; Membrane Glycoproteins / metabolism; Methyl-CpG-Binding Protein 2 / genetics; Methyl-CpG-Binding Protein 2 / metabolism; Mice, Mutant Strains; Pyrophosphatases / metabolism; Rett Syndrome / metabolism
Sources: Crossref, ORCID
Added: September 4, 2020

2016 journal article

Association between siesta (daytime sleep), dietary patterns and the presence of metabolic syndrome in elderly living in Mediterranean area (MEDIS study): The moderating effect of gender

The Journal of Nutrition, Health & Aging, 21(10), 1118–1124.

By: E. Georgousopoulou*, N. Naumovski*, D. Mellor*, S. Tyrovolas*, S. Piscopo*, G. Valacchi*, N. Tsakountakis*, A. Zeimbekis ...

co-author countries: Australia 🇦🇺 Spain 🇪🇸 Greece 🇬🇷 Italy 🇮🇹 Malta 🇲🇹 United States of America 🇺🇸
author keywords: Metabolic syndrome; sleep; elderly; diet; lifestyle; MEDIS; siesta; mediterranean-type diet
MeSH headings : Aged; Aged, 80 and over; Cross-Sectional Studies; Energy Intake / physiology; Feeding Behavior / physiology; Female; Gender Identity; Humans; Life Style; Male; Mediterranean Islands; Metabolic Syndrome / epidemiology; Metabolic Syndrome / etiology; Prevalence; Sleep / physiology
Sources: Crossref, ORCID
Added: January 21, 2021

2016 journal article

Cytokines profile and peripheral blood mononuclear cells morphology in Rett and autistic patients

Cytokine, 77, 180–188.

By: A. Pecorelli*, F. Cervellati*, G. Belmonte*, G. Montagner*, P. Waldon*, J. Hayek*, R. Gambari*, G. Valacchi*

co-author countries: Italy 🇮🇹 Korea (Republic of) 🇰🇷 United States of America 🇺🇸
author keywords: Rett syndrome; Autism spectrum disorders; Cytokine; Chemokine; Immune system; Peripheral blood mononuclear cells; Mitochondria
MeSH headings : Adolescent; Adult; Autistic Disorder / blood; Autistic Disorder / genetics; Child; Child, Preschool; Cytokines / blood; Cytokines / genetics; Gene Expression Profiling; Humans; Immunoenzyme Techniques / methods; Interleukin-13 / blood; Interleukin-13 / genetics; Interleukin-15 / blood; Interleukin-15 / genetics; Interleukin-1beta / blood; Interleukin-1beta / genetics; Interleukin-8 / blood; Interleukin-8 / genetics; Interleukin-9 / blood; Interleukin-9 / genetics; Leukocytes, Mononuclear / metabolism; Leukocytes, Mononuclear / ultrastructure; Microscopy, Electron, Transmission; Rett Syndrome / blood; Rett Syndrome / genetics; Reverse Transcriptase Polymerase Chain Reaction; Vascular Endothelial Growth Factor A / blood; Vascular Endothelial Growth Factor A / genetics; Young Adult
Sources: Crossref, ORCID
Added: September 4, 2020

2016 journal article

Decreased arylesterase activity of paraoxonase-1 (PON-1) might be a common denominator of neuroinflammatory and neurodegenerative diseases

The International Journal of Biochemistry & Cell Biology, 81, 356–363.

By: M. Castellazzi*, A. Trentini*, A. Romani*, G. Valacchi*, T. Bellini*, G. Bonaccorsi*, E. Fainardi*, C. Cavicchio* ...

co-author countries: Italy 🇮🇹
author keywords: Paraoxonase-1; Arylesterase activity; Multiple sclerosis; Alzheimer's disease; Vascular dementia
MeSH headings : Aged; Aryldialkylphosphatase / blood; Aryldialkylphosphatase / metabolism; Biomarkers / blood; Biomarkers / metabolism; Carboxylic Ester Hydrolases / blood; Carboxylic Ester Hydrolases / metabolism; Dementia / blood; Dementia / diagnosis; Dementia / enzymology; Female; Humans; Male; Multiple Sclerosis / blood; Multiple Sclerosis / diagnosis; Multiple Sclerosis / enzymology; Multiple Sclerosis / physiopathology; Neurodegenerative Diseases / blood; Neurodegenerative Diseases / diagnosis; Neurodegenerative Diseases / enzymology; Neurodegenerative Diseases / metabolism; Risk Factors
Sources: Crossref, ORCID
Added: September 4, 2020

2016 journal article

Design and Synthesis of New Transient Receptor Potential Vanilloid Type-1 (TRPV1) Channel Modulators: Identification, Molecular Modeling Analysis, and Pharmacological Characterization of the N-(4-Hydroxy-3-methoxybenzyl)-4-(thiophen-2-yl)butanamide, a Small Molecule Endowed with Agonist TRPV1 Activity and Protective Effects against Oxidative Stress

ACS Chemical Neuroscience, 7(6), 737–748.

By: F. Aiello*, M. Badolato*, F. Pessina, C. Sticozzi*, V. Maestrini, C. Aldinucci, L. Luongo*, F. Guida* ...

co-author countries: Italy 🇮🇹
author keywords: TRPV1 ligands; capsaicin; antioxidant; oxidative stress; neuroprotective; antinociceptive
MeSH headings : Analgesics / pharmacology; Animals; CHO Cells; Capsaicin / pharmacology; Cricetulus / metabolism; Male; Models, Molecular; Oxidative Stress / drug effects; Rats, Wistar; TRPV Cation Channels / agonists; TRPV Cation Channels / metabolism; Thiophenes / chemical synthesis; Thiophenes / chemistry; Thiophenes / pharmacology
Sources: Crossref, ORCID
Added: January 21, 2021

2016 journal article

Inhibitions of mTORC1 and 4EBP-1 are key events orchestrated by Rottlerin in SK-Mel-28 cell killing

Cancer Letters, 380(1), 106–113.

By: E. Daveri*, E. Maellaro*, G. Valacchi*, F. Ietta*, M. Muscettola* & E. Maioli*

co-author countries: Italy 🇮🇹
author keywords: Rottlerin; AMPK; mTOR; 4EBP-1; Autophagy; Protein synthesis
MeSH headings : Acetophenones / pharmacology; Adaptor Proteins, Signal Transducing / antagonists & inhibitors; Adaptor Proteins, Signal Transducing / metabolism; Antineoplastic Agents / pharmacology; Antineoplastic Agents / toxicity; Autophagy / drug effects; Benzopyrans / pharmacology; Cell Cycle Proteins; Cell Line; Dose-Response Relationship