Works (121)

Updated: March 2nd, 2024 07:18

2023 journal article

A science-based agenda for health-protective chemical assessments and decisions: overview and consensus statement

ENVIRONMENTAL HEALTH, 21(SUPPL 1).

By: T. Woodruff*, S. Rayasam*, D. Axelrad*, P. Koman*, N. Chartres*, D. Bennett*, L. Birnbaum*, P. Brown* ...

co-author countries: Canada 🇨🇦 United States of America 🇺🇸
author keywords: Chemicals; Conflicts of Interest; Environmental Health; Environmental Justice; EPA; Hazard Identification; Health Equity; Risk Assessment; TSCA
MeSH headings : Humans; Environmental Exposure / adverse effects; Environmental Exposure / prevention & control; Environmental Health; Environmental Pollutants / analysis; Public Health; Risk Assessment; Consensus Development Conferences as Topic
Sources: Web Of Science, ORCID
Added: March 6, 2023

2023 review

Advancing the science on chemical classes

[Review of ]. ENVIRONMENTAL HEALTH, 21(SUPPL 1).

By: M. Maffini*, S. Rayasam, D. Axelrad*, L. Birnbaum*, C. Cooper, S. Franjevic, P. MacRoy, K. Nachman* ...

co-author countries: United States of America 🇺🇸
author keywords: Chemical class; Regulation; Decision-making; Toxic chemicals; Risk assessment; Chemical grouping; Ortho-phthalates
MeSH headings : Humans; Hazardous Substances / toxicity; Risk Assessment / methods
Sources: Web Of Science, ORCID
Added: March 6, 2023

2023 journal article

Developmental organophosphate flame retardant exposure disrupts adult hippocampal neurogenesis in Wistar rats

NEUROTOXICOLOGY, 99, 104–114.

By: A. Newell n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Neurodevelopment; OPFR; OPE; Flame retardants; Neurotoxicity; Neurotoxicology; Postnatal; Reproductive and developmental toxicology; Hippocampus; Dentate gyrus; Adult hippocampal neurogenesis
Sources: Web Of Science, ORCID
Added: December 11, 2023

2023 journal article

Gestational exposure to FireMaster® 550 (FM 550) disrupts the placenta-brain axis in a socially monogamous rodent species, the prairie vole (Microtus ochrogaster)

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 576.

By: W. Marinello n, S. Gillera n, Y. Han*, J. Richardson*, G. St Armour n, B. Horman n, H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Pregnancy; EDCs; Endocrine disruptors; Neurotoxicology; Developmental toxicology; Organophosphate
Sources: Web Of Science, ORCID
Added: October 16, 2023

2023 article

Machine learning reveals common transcriptomic signatures across rat brain and placenta following developmental organophosphate ester exposure

Newell, A. J., Jima, D., Reading, B., & Patisaul, H. B. (2023, July 3). TOXICOLOGICAL SCIENCES, Vol. 7.

By: A. Newell n, D. Jima n, B. Reading n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: artificial intelligence; toxicogenomics; neurodevelopment; OPFR; OPE; flame retardants; neurotoxicology; hippocampus; cortex; placenta
Sources: Web Of Science, ORCID
Added: July 24, 2023

2023 journal article

Maternal organophosphate flame retardant exposure alters the developing mesencephalic dopamine system in fetal rat

TOXICOLOGICAL SCIENCES, 191(2), 357–373.

By: A. Newell n, V. Kapps n, Y. Cai n, M. Rai, G. St Armour n, B. Horman n, K. Rock n, S. Witchey n, A. Greenbaum n, H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: neurodevelopment; monoamine; OPFR; OPE; flame retardants; neurotransmitters; neurotoxicity; neurotoxicology; prenatal; reproductive and developmental toxicology; mesocortical dopamine system; tissue clearing light sheet microscopy.
Sources: Web Of Science, ORCID
Added: February 12, 2024

2023 journal article

Skeletal effects following developmental flame-retardant exposure are specific to sex and chemical class in the adult Wistar rat

FRONTIERS IN TOXICOLOGY, 5.

By: S. Schkoda n, B. Horman n, S. Witchey*, A. Jansson n, S. Macari* & H. Patisaul n

co-author countries: Brazil 🇧🇷 United States of America 🇺🇸
author keywords: endocrine disrupting chemicals; flame retardants; sex difference; osteotoxicology; computed tomography; bone
Sources: Web Of Science, ORCID
Added: August 28, 2023

2023 journal article

Uncovering the common factors of chemical exposure and behavior: Evaluating behavioral effects across a testing battery using factor analysis

NEUROTOXICOLOGY, 99, 264–273.

By: W. Marinello n, S. Gillera n, L. Huang n, J. Rollman n, D. Reif n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: EDCs; Endocrine disruptors; Neurodevelopment; Neurotoxicology; Organophosphate; Flame retardants; Vole; Behavior
Sources: Web Of Science, ORCID
Added: December 18, 2023

2022 journal article

Developmental nicotine exposure and masculinization of the rat preoptic area

NEUROTOXICOLOGY, 89, 41–54.

By: R. Joglekar*, M. Cauley*, T. Lipsich*, D. Corcoran*, H. Patisaul n, E. Levin*, J. Meyer*, M. McCarthy*, S. Murphy*

co-author countries: United States of America 🇺🇸
author keywords: Nicotine; Neurodevelopment; Sex differences; DNA methylation; Preoptic area; Toxicology; Sex behavior
MeSH headings : Animals; Electronic Nicotine Delivery Systems; Female; Male; Nicotine / toxicity; Preoptic Area / metabolism; Rats; Sex Characteristics; Sex Differentiation; Testosterone
Sources: Web Of Science, ORCID
Added: July 11, 2022

2022 article

Editorial: Women in developmental and reproductive toxicology: 2021

Adibi, J. J., Christiansen, S., Fenton, S. E., Holloway, A., & Patisaul, H. B. (2022, October 3). FRONTIERS IN TOXICOLOGY, Vol. 4.

co-author countries: Canada 🇨🇦 Denmark 🇩🇰 United States of America 🇺🇸
author keywords: mentor; women's health; gender; fetal; mammary gland; placenta
Sources: Web Of Science, ORCID
Added: June 26, 2023

2022 journal article

Effects of developmental exposure to FireMaster (R) 550 (FM 550) on microglia density, reactivity and morphology in a prosocial animal model

NEUROTOXICOLOGY, 91, 140–154.

By: W. Marinello n, S. Gillera n, M. Fanning n, L. Malinsky n, C. Rhodes n, B. Horman n, H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Prefrontal cortex; Sex difference; Neurodevelopment; Endocrine disrupting chemicals; Flame retardants; Vole
MeSH headings : Animals; Arvicolinae; Female; Humans; Male; Mice; Microglia; Models, Animal; Organophosphates; Polybrominated Biphenyls; Pregnancy; Rats
Sources: Web Of Science, ORCID
Added: June 20, 2022

2022 article

Impacts of Gestational FireMaster 550 (FM 550) Exposure on the Neonatal Cortex are Sex Specific and Largely Attributable to the Organophosphate Esters

Witchey, S. K., Doyle, M. G., Fredenburg, J. D., St Armour, G., Horman, B., Odenkirk, M. T., … Patisaul, H. B. (2022, September 8). NEUROENDOCRINOLOGY, Vol. 9.

By: S. Witchey n, M. Doyle n, J. Fredenburg n, G. St Armour n, B. Horman n, M. Odenkirk n, D. Aylor n, E. Baker n, H. Patisaul n

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: September 26, 2022

2022 journal article

Individual and Combined Effects of Paternal Deprivation and Developmental Exposure to Firemaster 550 on Socio-Emotional Behavior in Prairie Voles

TOXICS, 10(5).

By: S. Gillera n, W. Marinello n, M. Nelson n, B. Horman n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: endocrine disruptors; flame retardants; sexual differentiation; pair bond
Sources: Web Of Science, ORCID
Added: June 13, 2022

2022 article

Virtual Issue: Neurotoxicology

Sombers, L. A., & Patisaul, H. B. (2022, August 3). ACS CHEMICAL NEUROSCIENCE, Vol. 13, pp. 2238–2239.

By: L. Sombers* & H. Patisaul*

Sources: Web Of Science, ORCID
Added: August 15, 2022

2021 journal article

Beyond Cholinesterase Inhibition: Developmental Neurotoxicity of Organophosphate Ester Flame Retardants and Plasticizers

ENVIRONMENTAL HEALTH PERSPECTIVES, 129(10).

By: H. Patisaul n, M. Behl*, L. Birnbaum*, A. Blum*, M. Diamond*, S. Fernandez*, H. Hogberg*, C. Kwiatkowski n ...

co-author countries: Canada 🇨🇦 United States of America 🇺🇸
MeSH headings : Acetylcholinesterase; Child; Environmental Monitoring; Esters; Female; Flame Retardants / analysis; Humans; Organophosphates / urine; Placenta / metabolism; Plasticizers / analysis; Plasticizers / metabolism; Plasticizers / toxicity; Pregnancy
Sources: Web Of Science, ORCID
Added: November 29, 2021

2021 review

Endocrine disruption and reproductive disorders: impacts on sexually dimorphic neuroendocrine pathways

[Review of ]. REPRODUCTION, 162(5), F111–F130.

By: H. Patisaul n

co-author countries: United States of America 🇺🇸
MeSH headings : Endocrine Disruptors / toxicity; Female; Humans; Male; Neurosecretory Systems; Pregnancy; Puberty; Reproduction; Semen Analysis
Sources: Web Of Science, ORCID
Added: October 26, 2021

2021 journal article

FireMaster (R) 550 (FM 550) exposure during the perinatal period impacts partner preference behavior and nucleus accumbens core medium spiny neuron electrophysiology in adult male and female prairie voles, Microtus ochrogaster

HORMONES AND BEHAVIOR, 134.

By: A. Krentzel n, L. Kimble n, D. Dorris n, B. Horman n, J. Meitzen n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Vole; Electrophysiology; Nucleus accumbens; Flame  retardants; Endocrine disruptors; Neurodevelopment; Endocrine disrupting chemical
MeSH headings : Animals; Arvicolinae; Electrophysiology; Female; Grassland; Male; Neurons; Nucleus Accumbens; Organophosphates; Pair Bond; Polybrominated Biphenyls; Pregnancy; Social Behavior; Zebrafish
Sources: Web Of Science, ORCID
Added: September 7, 2021

2021 journal article

Interactions of the estrous cycle, novelty, and light on female and male rat open field locomotor and anxiety-related behaviors

PHYSIOLOGY & BEHAVIOR, 228.

By: C. Miller n, A. Halbing n, H. Patisaul n & J. Meitzen n

co-author countries: United States of America 🇺🇸
author keywords: Estrous cycle; Locomotor and anxiety-related behavior; Open-field; Novelty; Light; Sex differences
MeSH headings : Animals; Anxiety; Behavior, Animal; Estrous Cycle; Estrus; Female; Light; Male; Rats
Sources: Web Of Science, ORCID
Added: January 19, 2021

2021 article

Introduction to sex differences in neurotoxic effects

NEUROTOXICOLOGY AND TERATOLOGY, Vol. 83.

By: E. Levin*, D. Dow-Edwards* & H. Patisaul n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Environmental Exposure; Female; Humans; Male; Maternal Exposure; Maternal-Fetal Exchange; Neurotoxicity Syndromes / etiology; Neurotoxins / administration & dosage; Neurotoxins / toxicity; Paternal Exposure; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Sex Characteristics; Sexual Maturation; Stress, Physiological
Sources: Web Of Science, ORCID
Added: March 8, 2021

2021 journal article

Neural correlates of mating system diversity: oxytocin and vasopressin receptor distributions in monogamous and non-monogamous Eulemur

SCIENTIFIC REPORTS, 11(1).

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Biological Evolution; Brain / metabolism; Brain Mapping / methods; Evolution, Molecular; Female; Lemuridae / metabolism; Male; Memory; Neurosecretory Systems / metabolism; Oxytocin / metabolism; Pair Bond; Primates; Receptors, Oxytocin / metabolism; Receptors, Vasopressin / metabolism; Reproduction; Sexual Behavior, Animal / physiology; Social Behavior; Species Specificity; Vasopressins / metabolism
Sources: Web Of Science, ORCID
Added: March 15, 2021

2021 journal article

Neurotoxicity of Ortho-Phthalates: Recommendations for Critical Policy Reforms to Protect Brain Development in Children

AMERICAN JOURNAL OF PUBLIC HEALTH, 111(4), 687–695.

By: S. Engel n, H. Patisaul n, C. Brody n, R. Hauser n, A. Zota n, D. Bennet n, M. Swanson n, R. Whyatt n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Brain / drug effects; Child; Child Development / drug effects; Environmental Exposure / adverse effects; Female; Government Regulation; Humans; Infant; Longitudinal Studies; Male; Phthalic Acids / adverse effects; Phthalic Acids / toxicity; Policy Making; Pregnancy; Prenatal Exposure Delayed Effects; Reproduction / drug effects
Sources: Web Of Science, ORCID
Added: May 24, 2021

2021 journal article

Sex-specific Disruption of the Prairie Vole Hypothalamus by Developmental Exposure to a Flame Retardant Mixture

ENDOCRINOLOGY, 162(8).

By: S. Gillera n, W. Marinello n, K. Cao n, B. Horman n, H. Stapleton* & H. Patisaul n

co-author countries: United States of America 🇺🇸

Contributors: S. Gillera n, W. Marinello n, K. Cao n, B. Horman n, H. Stapleton* & H. Patisaul n

author keywords: Social; anxiety; neurodevelopment; neural; endocrine disruptors; endocrine disrupting chemicals; oxytocin; vasopressin; dopamine
MeSH headings : Animals; Arginine Vasopressin / metabolism; Arvicolinae; Endocrine Disruptors / toxicity; Female; Flame Retardants / toxicity; Male; Neurons / drug effects; Neurons / metabolism; Oxytocin / metabolism; Paraventricular Hypothalamic Nucleus / drug effects; Sex Factors; Tyrosine 3-Monooxygenase / metabolism
Sources: Web Of Science, ORCID
Added: July 12, 2021

2021 journal article

Transcriptomic, proteomic, and metabolomic analyses identify candidate pathways linking maternal cadmium exposure to altered neurodevelopment and behavior

SCIENTIFIC REPORTS, 11(1).

By: K. Hudson n, E. Shiver n, J. Yu*, S. Mehta n, D. Jima n, M. Kane*, H. Patisaul n, M. Cowley n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Body Weight / drug effects; Body Weight / genetics; Cadmium / toxicity; Female; Fetal Development / drug effects; Fetal Development / genetics; Humans; Maternal Exposure; Metabolomics / methods; Mice; Mice, Inbred C57BL; Neurodevelopmental Disorders / chemically induced; Neurodevelopmental Disorders / genetics; Placenta / drug effects; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / genetics; Proteomics / methods; Transcriptome / genetics
Sources: Web Of Science, ORCID
Added: August 30, 2021

2020 review

Achieving CLARITY on bisphenol A, brain and behaviour

[Review of ]. JOURNAL OF NEUROENDOCRINOLOGY, 32(1).

By: H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: amygdala; anxiety; EDC; endocrine disrupting chemical; hypothalamus; oxytocin
MeSH headings : Animals; Behavior, Animal / drug effects; Benzhydryl Compounds / toxicity; Brain / drug effects; Endocrine Disruptors / toxicity; Female; Humans; Male; Neurons / drug effects; Phenols / toxicity; Pregnancy; Sex Differentiation / drug effects; United States; United States Food and Drug Administration
Sources: Web Of Science, ORCID
Added: February 17, 2020

2020 journal article

Analysis of neurotransmitters in rat placenta exposed to flame retardants using IR-MALDESI mass spectrometry imaging

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 412(15), 3745–3752.

By: C. Pace n, B. Horman n, H. Patisaul n & D. Muddiman n

co-author countries: United States of America 🇺🇸
author keywords: IR-MALDESI; Mass spectrometry imaging; Neurotransmitters; Exposomics
MeSH headings : Animals; Female; Flame Retardants / adverse effects; Infrared Rays; Neurotransmitter Agents / analysis; Optical Imaging / instrumentation; Optical Imaging / methods; Placenta / chemistry; Placenta / diagnostic imaging; Pregnancy; Rats; Rats, Wistar; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / instrumentation; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
Sources: Web Of Science, ORCID
Added: June 1, 2020

2020 journal article

Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification

NATURE REVIEWS ENDOCRINOLOGY, 16(1), 45–57.

By: M. La Merrill*, L. Vandenberg*, M. Smith*, W. Goodson*, P. Browne*, H. Patisaul n, K. Guyton*, A. Kortenkamp* ...

co-author countries: France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Japan 🇯🇵 Netherlands 🇳🇱 United States of America 🇺🇸
MeSH headings : Animals; Consensus; Endocrine Disruptors / adverse effects; Environmental Exposure / adverse effects; Environmental Exposure / prevention & control; Environmental Pollutants / adverse effects; Environmental Pollutants / metabolism; Humans; Receptors, Corticotropin / metabolism
Sources: Web Of Science, ORCID
Added: December 30, 2019

2020 journal article

Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies

REPRODUCTIVE TOXICOLOGY, 98, 29–60.

By: J. Heindel*, S. Belcher n, J. Flaws*, G. Prins*, S. Ho*, J. Mao*, H. Patisaul n, W. Ricke* ...

co-author countries: United States of America 🇺🇸

Contributors: J. Heindel*, S. Belcher n, J. Flaws*, G. Prins*, S. Ho*, J. Mao*, H. Patisaul n, W. Ricke* ...

author keywords: CLARITY-BPA; Guideline study; Bisphenol A; EDC; Endocrine disruptor; GLP; Systemic effects
MeSH headings : Animals; Behavior, Animal / drug effects; Benzhydryl Compounds / toxicity; DNA Methylation; Endocrine Disruptors / toxicity; Female; Gene Expression Regulation, Developmental / drug effects; Heart / drug effects; Heart / growth & development; Male; Mammary Glands, Animal / drug effects; Mammary Glands, Animal / growth & development; Maternal-Fetal Exchange; Ovary / drug effects; Ovary / growth & development; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / genetics; Prostate / drug effects; Prostate / growth & development; Rats, Sprague-Dawley; Reproducibility of Results; Thyroid Gland / drug effects; Thyroid Gland / growth & development; Urethra / drug effects; Urethra / growth & development
Sources: Web Of Science, ORCID
Added: January 19, 2021

2020 journal article

Developmental Exposure to the Flame Retardant Mixture Firemaster 550 Compromises Adult Bone Integrity in Male but not Female Rats

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(7).

By: S. Macari*, K. Rock n, M. Santos*, V. Lima*, R. Szawka*, J. Moss n, B. Horman n, H. Patisaul n

co-author countries: Brazil 🇧🇷 United States of America 🇺🇸
author keywords: obesogen; endocrine disrupting chemicals; sex difference; adipose; trabecular; cortical bone; ppar gamma
MeSH headings : Animals; Bone and Bones / drug effects; Cellular Reprogramming / drug effects; Dust / analysis; Environmental Monitoring / methods; Female; Flame Retardants / adverse effects; Halogenation / drug effects; Lactation / drug effects; Male; Mesenchymal Stem Cells / drug effects; Organophosphates / adverse effects; Polybrominated Biphenyls / adverse effects; Rats; Rats, Wistar
Sources: Web Of Science, ORCID
Added: June 15, 2020

2020 journal article

Effects of Prenatal Exposure to a Mixture of Organophosphhate Flame Ritardants on Placental Gene Expression and Serotonergic Innervaion in the Fetal Rat Brain

TOXICOLOGICAL SCIENCES, 176(1), 203–223.

By: K. Rock n, G. St Armour n, B. Horman n, A. Phillips*, M. Ruis*, A. Stewart n, D. Jima n, D. Muddiman n, H. Stapleton*, H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: endocrine disruptors; endocrine toxicology; flame retardants; metabolome; neurotoxicity; developmental; neurotoxicology; neurotransmitter; developmental toxicity; prenatal; reproductive and developmental toxicology; developmental/teratology
MeSH headings : Animals; Brain / drug effects; Female; Fetal Development; Fetus; Flame Retardants / toxicity; Gene Expression; Humans; Male; Organophosphates; Organophosphorus Compounds; Placenta / metabolism; Plasticizers; Polybrominated Biphenyls; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Wistar; Serotonin / metabolism
Sources: Web Of Science, ORCID
Added: December 14, 2020

2020 journal article

Metabotropic glutamate receptor subtype 5 (mGlu(5)) is necessary for estradiol mitigation of light-induced anxiety behavior in female rats

PHYSIOLOGY & BEHAVIOR, 214.

By: C. Miller n, A. Krentzel n, H. Patisaul n & J. Meitzen n

co-author countries: United States of America 🇺🇸
author keywords: Estradiol; Metabotropic glutamate receptor 5; Female; Anxiety; Estrogen
MeSH headings : Animals; Anxiety / prevention & control; Estradiol / pharmacology; Estrogen Antagonists / pharmacology; Excitatory Amino Acid Antagonists / pharmacology; Female; Light; Locomotion / drug effects; Ovariectomy; Pyridines / pharmacology; Rats; Receptor, Metabotropic Glutamate 5 / metabolism
Sources: Web Of Science, ORCID
Added: February 10, 2020

2020 journal article

Temporal and bidirectional influences of estradiol on voluntary wheel running in adult female and male rats

HORMONES AND BEHAVIOR, 120.

By: A. Krentzel n, S. Proano n, H. Patisaul n & J. Meitzen n

co-author countries: United States of America 🇺🇸
author keywords: Estradiol; Sex differences; Voluntary wheel running; Locomotion; Motivation
MeSH headings : Animals; Behavior, Animal / drug effects; Estradiol / analogs & derivatives; Estradiol / pharmacology; Female; Male; Motivation / drug effects; Motor Activity / drug effects; Rats; Rats, Sprague-Dawley; Running / physiology; Sex Characteristics; Time Factors
Sources: Web Of Science, ORCID
Added: April 20, 2020

2020 review

The Use and Misuse of Historical Controls in Regulatory Toxicology: Lessons from the CLARITY-BPA Study

[Review of ]. ENDOCRINOLOGY, 161(5).

By: L. Vandenberg*, G. Prins*, H. Patisaul n & R. Zoeller*

co-author countries: United States of America 🇺🇸
author keywords: adenocarcinoma; Food and Drug Administration; gavage; lymphocyte infiltration; National Toxicology Program; obesity
MeSH headings : Animals; Benzhydryl Compounds / poisoning; Benzhydryl Compounds / toxicity; Ecotoxicology / methods; Ecotoxicology / standards; Endocrine Disruptors / poisoning; Endocrine Disruptors / toxicity; Environmental Exposure / adverse effects; Environmental Exposure / analysis; Guidelines as Topic; Humans; National Institute of Environmental Health Sciences (U.S.); Phenols / poisoning; Phenols / toxicity; Toxicity Tests / methods; Toxicity Tests / standards; United States; United States Food and Drug Administration
Sources: Web Of Science, ORCID
Added: June 1, 2020

2019 journal article

PBDEs Concentrate in the Fetal Portion of the Placenta: Implications for Thyroid Hormone Dysregulation

ENDOCRINOLOGY, 160(11), 2748–2758.

By: M. Ruis*, K. Rock n, S. Hall*, B. Horman n, H. Patisaul n & H. Stapleton n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Female; Halogenated Diphenyl Ethers / pharmacokinetics; Humans; Male; Membrane Transport Proteins / metabolism; Placenta / metabolism; Pregnancy; Rats, Wistar; Thyroid Hormones / metabolism
Sources: Web Of Science, ORCID
Added: January 27, 2020

2019 journal article

Perinatal bisphenol A (BPA) exposure alters brain oxytocin receptor (OTR) expression in a sex- and region- specific manner: A CLARITY-BPA consortium follow-up study

NEUROTOXICOLOGY, 74, 139–148.

By: S. Witchey n, J. Fuchs n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Behavior; Estrogen; Endocrine disruption; Sexual differentiation; Neuroendocrine; Oxytocin
MeSH headings : Animals; Animals, Newborn; Benzhydryl Compounds / toxicity; Brain Chemistry / drug effects; Endocrine Disruptors / toxicity; Ethinyl Estradiol / toxicity; Female; Hypothalamus / drug effects; Hypothalamus / metabolism; Male; Oxytocin / biosynthesis; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / metabolism; Rats; Rats, Sprague-Dawley; Receptors, Oxytocin / biosynthesis; Septal Nuclei / drug effects; Septal Nuclei / metabolism; Sex Characteristics
Sources: Web Of Science, ORCID
Added: October 21, 2019

2019 journal article

Sex-specific behavioral effects following developmental exposure to tetrabromobisphenol A (TBBPA) in Wistar rats

NEUROTOXICOLOGY, 75, 136–147.

co-author countries: United States of America 🇺🇸
author keywords: brain; anxiety; endocrine disruptions; sex differences; hyperactivity; neural; sexually dimorphic; neurotoxic; flame retardants; elevated plus maze; neurodevelopment
MeSH headings : Animals; Behavior, Animal / drug effects; Dose-Response Relationship, Drug; Endocrine Disruptors / toxicity; Flame Retardants / toxicity; Maze Learning / drug effects; Motor Activity / drug effects; Polybrominated Biphenyls / toxicity; Rats; Rats, Wistar / growth & development; Sex Factors
Sources: Web Of Science, ORCID
Added: December 16, 2019

2018 journal article

Animal models of endocrine disruption

BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 32(3), 283–297.

By: H. Patisaul n, S. Fenton* & D. Aylor n

co-author countries: United States of America 🇺🇸
author keywords: vole; peromyscus; toxicology; neurosciences; collaborative cross; PFOA
MeSH headings : Animals; Disease Models, Animal; Endocrine Disruptors / toxicity; Endocrine System / drug effects; Endocrine System Diseases / chemically induced; Endocrine System Diseases / pathology; Environmental Exposure / adverse effects; Environmental Illness / chemically induced; Environmental Illness / pathology; Humans; Reproducibility of Results; Reproduction / drug effects; Reproduction / physiology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

CLARITY-BPA academic laboratory studies identify consistent low-dose Bisphenol A effects on multiple organ systems

Basic & Clinical Pharmacology & Toxicology, 10(S3), 14–31.

By: G. Prins*, H. Patisaul n, S. Belcher n & L. Vandenberg*

co-author countries: United States of America 🇺🇸

Contributors: G. Prins*, H. Patisaul n, S. Belcher n & L. Vandenberg*

author keywords: Bisphenol A; CLARITY-BPA; endocrine disruptor; endocrine-disrupting chemical; oestrogen
MeSH headings : Animals; Benzhydryl Compounds / toxicity; Congresses as Topic; Disease Models, Animal; Ecotoxicology / methods; Ecotoxicology / standards; Endocrine Disruptors / toxicity; Environmental Exposure / adverse effects; Environmental Pollutants / toxicity; Female; Fetal Development / drug effects; Guidelines as Topic; Humans; National Institute of Environmental Health Sciences (U.S.) / standards; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / prevention & control; Rats, Sprague-Dawley; Risk Assessment / methods; Risk Assessment / standards; Toxicity Tests / methods; Toxicity Tests / standards; United States; United States Food and Drug Administration / standards
Sources: Crossref, ORCID
Added: August 17, 2019

2018 journal article

EDC IMPACT: Molecular effects of developmental FM 550 exposure in Wistar rat placenta and fetal forebrain

ENDOCRINE CONNECTIONS, 7(2), 305–324.

By: K. Rock n, B. Horman n, A. Phillips*, S. McRitchie*, S. Watson*, J. Deese-Spruill*, D. Jima n, S. Sumner n ...

co-author countries: United States of America 🇺🇸
author keywords: endocrine disruptors; flame retardants; behavior; serotonin; sexually dimorphic; EDC; brain
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Endocrine disruptors and the developing immune system

Current Opinion in Toxicology, 10, 31–36.

By: J. DeWitt* & H. Patisaul n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: January 25, 2020

2018 journal article

Environmental Mechanisms of Neurodevelopmental Toxicity

Current Environmental Health Reports, 5(1), 145–157.

By: K. Rock n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Neurodevelopment; Neurotoxicity; Xenobiotic; Neuroendocrine; Neuroimmune
MeSH headings : Brain / drug effects; Brain / growth & development; Environmental Exposure / adverse effects; Humans; Immune System / drug effects; Neurodevelopmental Disorders / chemically induced; Neurosecretory Systems / drug effects; Oxidative Stress / drug effects
Sources: Crossref, ORCID
Added: August 17, 2019

2018 journal article

IR-MALDESI mass spectrometry imaging of underivatized neurotransmitters in brain tissue of rats exposed to tetrabromobisphenol A

ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 410(30), 7979–7986.

By: M. Bagley n, M. Ekelof n, K. Rock n, H. Patisaul n & D. Muddiman n

co-author countries: United States of America 🇺🇸
author keywords: IR-MALDESI; Neurotransmitters; Mass spectrometry imaging; Exposomics; Orbitrap
MeSH headings : Animals; Brain; Female; Infrared Rays; Neurotransmitter Agents / chemistry; Polybrominated Biphenyls / toxicity; Rats; Spectrometry, Mass, Electrospray Ionization / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization / methods
Sources: Web Of Science, ORCID
Added: December 3, 2018

2018 journal article

Individual Variation in Social Behaviours of Male Lab-reared Prairie voles (Microtus ochrogaster) is Non-heritable and Weakly Associated with V1aR Density

Scientific Reports, 8(1), 1396.

By: A. Vogel, H. Patisaul*, S. Arambula, F. Tiezzi & L. McGraw*

Contributors: A. Vogel, H. Patisaul*, S. Arambula, F. Tiezzi & L. McGraw*

MeSH headings : Animals; Arvicolinae / physiology; Basal Forebrain / metabolism; Female; Male; Mating Preference, Animal; Pair Bond; Receptors, Vasopressin / metabolism; Social Behavior
Sources: Crossref, ORCID
Added: August 17, 2019

2018 article

Introduction to the special issue on endocrine disrupting chemicals and behavior

Barrett, E. S., & Patisaul, H. B. (2018, May). HORMONES AND BEHAVIOR, Vol. 101, pp. 1–2.

By: E. Barrett* & H. Patisaul n

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 review

Neurodevelopmental and neurological effects of chemicals associated with unconventional oil and natural gas operations and their potential effects on infants and children

[Review of ]. REVIEWS ON ENVIRONMENTAL HEALTH, 33(1), 3–29.

By: E. Webb*, J. Moon*, L. Dyrszka, B. Rodriguez*, C. Cox*, H. Patisaul n, S. Bushkin, E. London

co-author countries: United States of America 🇺🇸
author keywords: BTEX; children; EDCs; heavy metals; PAHs; particulate matter; UOG
MeSH headings : Adolescent; Air Pollutants / toxicity; Child; Child, Preschool; Congenital Abnormalities / etiology; Environmental Exposure / adverse effects; Humans; Infant; Infant, Newborn; Learning Disabilities / chemically induced; Natural Gas; Neurodevelopmental Disorders / chemically induced; Oil and Gas Industry; Petroleum; Water Pollutants, Chemical / toxicity
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

Novel unconditioned prosocial behavior in prairie voles (Microtus ochrogaster) as a model for empathy

BMC Research Notes, 11(1).

By: L. Stetzik*, A. Sullivan n, H. Patisaul n & B. Cushing*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Arginine Vasopressin / genetics; Arginine Vasopressin / metabolism; Arvicolinae / physiology; Arvicolinae / psychology; Behavior, Animal / physiology; Cooperative Behavior; Dopaminergic Neurons / cytology; Dopaminergic Neurons / metabolism; Empathy / physiology; Female; Gene Expression; Humans; Hypothalamus / cytology; Hypothalamus / metabolism; Male; Models, Animal; Oxytocin / genetics; Oxytocin / metabolism; Paraventricular Hypothalamic Nucleus / cytology; Paraventricular Hypothalamic Nucleus / metabolism; Tyrosine 3-Monooxygenase / genetics; Tyrosine 3-Monooxygenase / metabolism
Sources: Crossref, ORCID
Added: August 17, 2019

2018 journal article

Nucleus accumbens core medium spiny neuron electrophysiological properties and partner preference behavior in the adult male prairie vole, Microtus ochrogaster

Journal of Neurophysiology, 119(4), 1576–1588.

By: J. Willett n, A. Johnson n, A. Vogel n, H. Patisaul n, L. McGraw n & J. Meitzen n

co-author countries: United States of America 🇺🇸
author keywords: electrophysiology; medium spiny neuron; nucleus accumbens; rat; vole
MeSH headings : Action Potentials / physiology; Animals; Arvicolinae / physiology; Excitatory Postsynaptic Potentials / physiology; Male; Mating Preference, Animal / physiology; Neurons / physiology; Nucleus Accumbens / physiology; Patch-Clamp Techniques; Social Behavior
Sources: Crossref, ORCID
Added: August 17, 2019

2018 journal article

Prenatal bisphenol A (BPA) exposure alters the transcriptome of the neonate rat amygdala in a sex-specific manner: a CLARITY-BPA consortium study

NEUROTOXICOLOGY, 65, 207–220.

By: S. Arambula n, D. Jima n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Endocrine disruptor; EDC; Brain; Oxytocin; Sex difference; Estrogen; Androgen
MeSH headings : Amygdala / drug effects; Amygdala / metabolism; Animals; Animals, Newborn; Benzhydryl Compounds / toxicity; Dose-Response Relationship, Drug; Ethinyl Estradiol / pharmacology; Female; Male; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / metabolism; Rats; Sex Characteristics; Signal Transduction / drug effects; Transcriptome / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2018 journal article

The NIEHS TaRGET II Consortium and environmental epigenomics

Nature Biotechnology, 36(3), 225–227.

By: T. Wang*, E. Pehrsson*, D. Purushotham*, D. Li*, X. Zhuo*, B. Zhang, H. Lawson*, M. Province* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Environmental Exposure / adverse effects; Epigenomics; Genome / drug effects; Humans; National Institute of Environmental Health Sciences (U.S.); United States
Source: Crossref
Added: January 25, 2020

2018 personal communication

The NIEHS TaRGET II Consortium and environmental epigenomics

By: T. Wang, E. Pehrsson, D. Purushotham, D. Li, X. Zhuo, B. Zhang, H. Lawson, M. Province ...

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Chemical Contributions to Neurodevelopmental Disorders

Policy Insights from the Behavioral and Brain Sciences, 4(2), 123–130.

By: H. Patisaul n

co-author countries: United States of America 🇺🇸

Ed(s): S. Fiske

Sources: Crossref, ORCID
Added: August 17, 2019

2017 journal article

Effects of perinatal bisphenol A exposure on the volume of sexually-dimorphic nuclei of juvenile rats: A CLARITY-SPA consortium study

NEUROTOXICOLOGY, 63, 33–42.

By: S. Arambula n, J. Fuchs n, J. Cao n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Bisphenol A; Brain; Hypothalamus; Amygdala; Locus coeruleus; Sexually dimorphic
MeSH headings : Analysis of Variance; Animals; Animals, Newborn; Benzhydryl Compounds / toxicity; Brain / drug effects; Brain / pathology; Dose-Response Relationship, Drug; Endocrine Disruptors / toxicity; Estrogens / pharmacology; Ethinyl Estradiol / pharmacology; Female; Male; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Rats; Rats, Sprague-Dawley; Sex Characteristics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Endocrine Disruption of Vasopressin Systems and Related Behaviors

Frontiers in Endocrinology, 8.

By: H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: bisphenol; oxytocin; sex differences; EDC; genistein; soy; social; anxiety; estrogens
Sources: Crossref, ORCID
Added: August 17, 2019

2017 article

Endocrine disrupting chemicals and behavior: Re-evaluating the science at a critical turning point

Barrett, E. S., & Patisaul, H. B. (2017, November). HORMONES AND BEHAVIOR, Vol. 96, pp. A1–A6.

By: E. Barrett* & H. Patisaul n

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Environmental endocrine disruption of brain and behavior

Hormones, Brain and Behavior, Vol 5: Development of Hormone-Behavior Relationships, 3rd Edition, 63–88.

By: H. Patisaul, A. Gore & D. Crews

Source: NC State University Libraries
Added: August 6, 2018

2017 journal article

Sex Specific Placental Accumulation and Behavioral Effects of Developmental Firemaster 550 Exposure in Wistar Rats

SCIENTIFIC REPORTS, 7.

By: K. Baldwin n, A. Phillips*, B. Horman n, S. Arambula n, M. Rebuli n, H. Stapleton*, H. Patisaul n

co-author countries: United States of America 🇺🇸
MeSH headings : Age Factors; Analysis of Variance; Animals; Behavior, Animal / drug effects; Dose-Response Relationship, Drug; Female; Flame Retardants / adverse effects; Flame Retardants / analysis; Male; Molecular Structure; Placenta / drug effects; Placenta / metabolism; Pregnancy; Rats; Rats, Wistar; Sex Factors
Sources: Web Of Science, ORCID
Added: August 6, 2018

2017 journal article

Simultaneous Voltammetric Measurements of Glucose and Dopamine Demonstrate the Coupling of Glucose Availability with Increased Metabolic Demand in the Rat Striatum

ACS Chemical Neuroscience, 8(2), 272–280.

By: S. Smith n, C. Lee n, M. Dausch n, B. Horman n, H. Patisaul n, G. McCarty n, L. Sombers n

co-author countries: United States of America 🇺🇸
author keywords: Biosensor; carbon fiber microelectrode; neuroenergetics; glucose oxidase; cocaine; fast-scan cyclic voltammetry
MeSH headings : Animals; Biophysics; Cocaine / pharmacology; Corpus Striatum / cytology; Corpus Striatum / diagnostic imaging; Corpus Striatum / drug effects; Corpus Striatum / metabolism; Dopamine / metabolism; Dopamine Antagonists / pharmacology; Dopamine Uptake Inhibitors / pharmacology; Drug Combinations; Electric Stimulation; Extracellular Fluid / metabolism; Glial Fibrillary Acidic Protein / metabolism; Glucose / metabolism; Hydrogen Peroxide / metabolism; Male; Microelectrodes; Raclopride / pharmacology; Rats; Rats, Sprague-Dawley; Tyrosine 3-Monooxygenase / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2016 article

Assessment of sex specific endocrine disrupting effects in the prenatal and pre-pubertal rodent brain

Rebuli, M. E., & Patisaul, H. B. (2016, June). JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, Vol. 160, pp. 148–159.

By: M. Rebuli n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Endocrine disrupting compounds; Neurodevelopment; Sex differences; Developmental exposure; Rodent; Bisphenol; BPA; Genistein; Xenoestrogen; EDC
MeSH headings : Animals; Brain / drug effects; Brain / embryology; Brain / growth & development; Endocrine Disruptors / pharmacology; Female; Male; Puberty / drug effects; Rodentia / embryology; Rodentia / growth & development; Sex Characteristics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Endocrine disruption by dietary phyto-oestrogens: impact on dimorphic sexual systems and behaviours

Proceedings of the Nutrition Society, 76(2), 130–144.

By: H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Soya; Isoflavones; Genistein; Equol; Endocrine disruption; Oestrogen; ER; ER; Brain; Hypothalamus
MeSH headings : Animals; Benzhydryl Compounds / adverse effects; Diet; Disease Models, Animal; Endocrine Disruptors / adverse effects; Humans; Isoflavones / adverse effects; Neurosecretory Systems / drug effects; Phenols / adverse effects; Phytoestrogens / adverse effects; Reproduction / drug effects; Sexual Behavior / drug effects; Sexual Behavior, Animal / drug effects; Soybeans / chemistry
Sources: Crossref, ORCID
Added: August 17, 2019

2016 journal article

Impact of Low Dose Oral Exposure to Bisphenol A (BPA) on the Neonatal Rat Hypothalamic and Hippocampal Transcriptome: A CLARITY-BPA Consortium Study

Endocrinology, 157(10), 3856–3872.

By: S. Arambula n, S. Belcher n, A. Planchart n, S. Turner* & H. Patisaul n

co-author countries: United States of America 🇺🇸

Contributors: S. Arambula n, S. Belcher n, A. Planchart n, S. Turner* & H. Patisaul n

MeSH headings : Administration, Oral; Animals; Animals, Newborn; Benzhydryl Compounds / administration & dosage; Benzhydryl Compounds / toxicity; Estrogens, Non-Steroidal / administration & dosage; Estrogens, Non-Steroidal / toxicity; Female; Gene Expression / drug effects; Hippocampus / drug effects; Hippocampus / metabolism; Hypothalamus / drug effects; Hypothalamus / metabolism; Male; Phenols / administration & dosage; Phenols / toxicity; Random Allocation; Rats; Rats, Sprague-Dawley; Sex Characteristics; Transcriptome / drug effects
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2016 journal article

Interaction of bisphenol A (BPA) and soy phytoestrogens on sexually dimorphic sociosexual behaviors in male and female rats

HORMONES AND BEHAVIOR, 84, 121–126.

By: K. Hicks n, A. Sullivan n, J. Cao n, E. Sluzas n, M. Rebuli n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Endocrine disruption; Neuroendocrine disruption; Neuropeptides; Social; Diet; Open field; Affiliation; Activity; Environment
MeSH headings : Animals; Benzhydryl Compounds / pharmacology; Endocrine Disruptors / pharmacology; Exploratory Behavior / drug effects; Female; Isoflavones / pharmacology; Male; Phenols / pharmacology; Phytoestrogens / pharmacology; Rats; Sexual Behavior, Animal / drug effects; Social Behavior
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Sex differences in microglial colonization and vulnerabilities to endocrine disruption in the social brain

GENERAL AND COMPARATIVE ENDOCRINOLOGY, 238, 39–46.

By: M. Rebuli n, P. Gibson n, C. Rhodes n, B. Cushing* & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Vole; Rat; Hypothalamus; EDC; Sexual differentiation; Puberty
MeSH headings : Amygdala / cytology; Amygdala / drug effects; Animals; Animals, Newborn; Arvicolinae; Benzhydryl Compounds / toxicity; Brain / cytology; Brain / drug effects; Brain / growth & development; Dentate Gyrus / cytology; Dentate Gyrus / drug effects; Endocrine Disruptors / toxicity; Female; Male; Microglia / drug effects; Microglia / metabolism; Phenols / toxicity; Rats, Wistar; Sex Characteristics; Social Behavior; Somatosensory Cortex / cytology; Somatosensory Cortex / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 journal article

Transplacental and Lactational Transfer of Firemaster (R) 550 Components in Dosed Wistar Rats

TOXICOLOGICAL SCIENCES, 153(2), 246–257.

By: A. Phillips, A. Chen, K. Rock*, B. Horman*, H. Patisaul* & H. Stapleton

author keywords: Firemaster 550; lactational transfer; gestational transfer; metabolites; rodent
MeSH headings : Animals; Dose-Response Relationship, Drug; Female; Flame Retardants / pharmacokinetics; Lactation; Male; Maternal-Fetal Exchange; Placenta / metabolism; Pregnancy; Rats; Rats, Wistar
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Impact of Gestational Bisphenol A on Oxidative Stress and Free Fatty Acids: Human Association and Interspecies Animal Testing Studies

ENDOCRINOLOGY, 156(3), 911–922.

By: A. Veiga-Lopez*, S. Pennathur*, K. Kannan*, H. Patisaul n, D. Dolinoy*, L. Zeng*, V. Padmanabhan

co-author countries: United States of America 🇺🇸
MeSH headings : Adult; Animals; Benzhydryl Compounds / blood; Benzhydryl Compounds / toxicity; Biomarkers; Environmental Pollutants; Fatty Acids, Nonesterified / metabolism; Female; Fetal Blood / chemistry; Fetus / drug effects; Humans; Hypopituitarism; Maternal Exposure; Mice; Oxidative Stress; Phenols / blood; Phenols / toxicity; Pregnancy; Rats; Species Specificity
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Impact of Low-Dose Oral Exposure to Bisphenol A (BPA) on Juvenile and Adult Rat Exploratory and Anxiety Behavior: A CLARITY-BPA Consortium Study

TOXICOLOGICAL SCIENCES, 148(2), 341–354.

By: M. Rebuli n, L. Camacho*, M. Adonay n, D. Reif n, D. Aylor n & H. Patisaul n

co-author countries: United States of America 🇺🇸

Contributors: M. Rebuli n, L. Camacho*, M. Adonay n, D. Reif n, D. Aylor n & H. Patisaul n

author keywords: bisphenol A; CLARITY; behavior; anxiety; exploratory activity; endocrine disruption; EDC; sexually dimorphic; brain; BPA; plastic
MeSH headings : Age Factors; Animals; Anxiety / chemically induced; Anxiety / psychology; Behavior, Animal / drug effects; Benzhydryl Compounds / toxicity; Dose-Response Relationship, Drug; Endocrine Disruptors / toxicity; Exploratory Behavior / drug effects; Female; Gestational Age; Lactation; Male; Maternal Exposure / adverse effects; Motor Activity / drug effects; Neurotoxicity Syndromes / etiology; Neurotoxicity Syndromes / psychology; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Sprague-Dawley; Risk Assessment; Sex Factors
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

Soy but not bisphenol A (BPA) or the phytoestrogen genistin alters developmental weight gain and food intake in pregnant rats and their offspring

REPRODUCTIVE TOXICOLOGY, 58, 282–294.

By: J. Cao n, R. Echelberger n, M. Liu*, E. Sluzas n, K. McCaffrey n, B. Buckley*, H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Endocrine disruption; Genistein; Phytoestrogens; Behavior; Sexually dimorphic; Obesogen; Body weight; Metabolic
MeSH headings : Age Factors; Animal Nutritional Physiological Phenomena / drug effects; Animals; Benzhydryl Compounds / metabolism; Benzhydryl Compounds / toxicity; Dietary Proteins / metabolism; Dietary Proteins / toxicity; Eating / drug effects; Endocrine Disruptors / metabolism; Endocrine Disruptors / toxicity; Female; Genistein / metabolism; Genistein / toxicity; Male; Maternal Nutritional Physiological Phenomena / drug effects; Nutritional Status / drug effects; Obesity / chemically induced; Obesity / physiopathology; Phenols / metabolism; Phenols / toxicity; Phytoestrogens / metabolism; Phytoestrogens / toxicity; Pregnancy; Prenatal Exposure Delayed Effects; Rats, Wistar; Risk Assessment; Sexual Maturation / drug effects; Soybean Proteins / metabolism; Soybean Proteins / toxicity; Weight Gain / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

A Novel Model for Neuroendocrine Toxicology: Neurobehavioral Effects of BPA Exposure in a Prosocial Species, the Prairie Vole (Microtus ochrogaster)

ENDOCRINOLOGY, 155(10), 3867–3881.

By: A. Sullivan n, E. Beach*, L. Stetzik*, A. Perry*, . Alyssa S. D'Addezio n, B. Cushing*, H. Patisaul n

co-author countries: United States of America 🇺🇸
MeSH headings : Affect / drug effects; Animals; Arvicolinae / physiology; Arvicolinae / psychology; Behavior, Animal / drug effects; Benzhydryl Compounds / toxicity; Defense Mechanisms; Endocrine Disruptors / toxicity; Environmental Exposure; Environmental Pollutants / toxicity; Female; Male; Models, Animal; Motor Activity / drug effects; Neurosecretory Systems / drug effects; Phenols / toxicity; Social Behavior; Toxicity Tests
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

In vitro assessment of human nuclear hormone receptor activity and cytotoxicity of the flame retardant mixture FM 550 and its triarylphosphate and brominated components

Toxicology Letters, 228(2), 93–102.

By: S. Belcher*, C. Cookman*, H. Patisaul n & H. Stapleton*

co-author countries: United States of America 🇺🇸

Contributors: S. Belcher*, C. Cookman*, H. Patisaul n & H. Stapleton*

author keywords: Apoptosis Endocrine disruptor; Flame retardant; Nuclear receptors; Obesity; Peroxisome proliferator-activated receptor
MeSH headings : Adipocytes / drug effects; Animals; CHO Cells; Caspase 3 / metabolism; Cell Survival / drug effects; Cricetinae; Cricetulus; Endocrine Disruptors / toxicity; Flame Retardants / toxicity; Humans; Ligands; Organophosphates / chemistry; Organophosphates / toxicity; Organotin Compounds / toxicity; PPAR gamma / drug effects; PPAR gamma / metabolism; Receptors, Cytoplasmic and Nuclear / drug effects; Transcriptional Activation / drug effects
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2014 journal article

Investigation of the Effects of Subchronic Low Dose Oral Exposure to Bisphenol A (BPA) and Ethinyl Estradiol (EE) on Estrogen Receptor Expression in the Juvenile and Adult Female Rat Hypothalamus

TOXICOLOGICAL SCIENCES, 140(1), 190–203.

By: M. Rebuli n, J. Cao n, E. Sluzas n, K. Delclos*, L. Camacho*, S. Lewis*, M. Vanlandingham*, H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: brain; endocrine disruptor; endocrine disruption; hypothalamus; development; subchronic exposure; sexually dimorphic; ethinyl estradiol; bisphenol A
MeSH headings : Aging / metabolism; Animals; Benzhydryl Compounds / toxicity; Dose-Response Relationship, Drug; Estrogen Receptor alpha / genetics; Estrogen Receptor beta / genetics; Ethinyl Estradiol / toxicity; Female; Gene Expression / drug effects; Hypothalamus / drug effects; Hypothalamus / embryology; Hypothalamus / growth & development; Hypothalamus / metabolism; Male; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / metabolism; Rats, Sprague-Dawley; Receptors, Estrogen / genetics; Sex Characteristics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 article

Sex-specific Esr2 mRNA expression in the rat hypothalamus and amygdala is altered by neonatal bisphenol A exposure

Cao, J., Joyner, L., Mickens, J. A., Leyrer, S. M., & Patisaul, H. B. (2014, April). REPRODUCTION, Vol. 147, pp. 537–554.

By: J. Cao*, L. Joyner, J. Mickens*, S. Leyrer & H. Patisaul*

MeSH headings : Amygdala / drug effects; Amygdala / growth & development; Amygdala / metabolism; Animals; Animals, Newborn; Behavior, Animal / drug effects; Benzhydryl Compounds / toxicity; Dose-Response Relationship, Drug; Estradiol / analogs & derivatives; Estradiol / pharmacology; Estrogen Receptor beta / genetics; Estrogen Receptor beta / metabolism; Female; Gene Expression Regulation, Developmental / drug effects; Hypothalamus / drug effects; Hypothalamus / growth & development; Hypothalamus / metabolism; Male; Phenols / toxicity; Rats; Rats, Long-Evans; Sex Factors; Sexual Behavior, Animal / drug effects; Social Behavior
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Soy but not bisphenol A (BPA) induces hallmarks of polycystic ovary syndrome (PCOS) and related metabolic co-morbidities in rats

REPRODUCTIVE TOXICOLOGY, 49, 209–218.

By: H. Patisaul n, N. Mabrey n, H. Adewale n & A. Sullivan n

co-author countries: United States of America 🇺🇸
author keywords: Phytoestrogens; Genistein; Endocrine disruptors; Ovary; Development
MeSH headings : Animals; Benzhydryl Compounds / adverse effects; Diet / adverse effects; Endocrine Disruptors / adverse effects; Female; Ovary / drug effects; Ovary / pathology; Phenols / adverse effects; Polycystic Ovary Syndrome / chemically induced; Polycystic Ovary Syndrome / pathology; Pregnancy; Rats; Rats, Wistar; Soy Foods / adverse effects; Testosterone / blood
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Test driving ToxCast: endocrine profiling for 1858 chemicals included in phase II

CURRENT OPINION IN PHARMACOLOGY, 19, 145–152.

By: D. Filer*, H. Patisaul n, T. Schug*, D. Reif n & K. Thayer*

co-author countries: United States of America 🇺🇸

Contributors: D. Filer*, H. Patisaul n, T. Schug*, D. Reif n & K. Thayer*

MeSH headings : Animals; Databases, Factual; Endocrine Disruptors / toxicity; High-Throughput Screening Assays; Humans; Models, Theoretical; Risk Assessment; United States; United States Environmental Protection Agency
Sources: Web Of Science, ORCID
Added: August 6, 2018

2014 journal article

Urinary Tetrabromobenzoic Acid (TBBA) as a Biomarker of Exposure to the Flame Retardant Mixture Firemaster ® 550

Environmental Health Perspectives, 122(9), 963–969.

co-author countries: United States of America 🇺🇸
MeSH headings : Adult; Aged; Animals; Biomarkers / metabolism; Bromobenzoates / urine; Dust / analysis; Environmental Exposure / analysis; Environmental Pollutants / urine; Female; Flame Retardants / metabolism; Hand; Humans; Male; Mass Spectrometry / methods; Middle Aged; Organophosphates / urine; Phthalic Acids / urine; Polybrominated Biphenyls / urine; Rats
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2013 journal article

Decoding the language of epigenetics during neural development is key for understanding development as well as developmental neurotoxicity

EPIGENETICS, 8(11), 1128–1132.

By: M. Yeo*, H. Patisaul n & W. Liedtke*

co-author countries: Netherlands 🇳🇱 United States of America 🇺🇸
author keywords: neurodevelopmental toxicity; bisphenol A; chloride shift; KCC2; SLC12A5
MeSH headings : Air Pollutants, Occupational / adverse effects; Animals; Benzhydryl Compounds / adverse effects; Cerebral Cortex / metabolism; Chlorides / metabolism; Epigenesis, Genetic / drug effects; Female; Humans; Male; Nerve Tissue Proteins / metabolism; Neurons / metabolism; Phenols / adverse effects; Response Elements; Symporters / biosynthesis
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Designing endocrine disruption out of the next generation of chemicals

Green Chem., 15(1), 181–198.

By: T. Schug*, R. Abagyan*, B. Blumberg*, T. Collins*, D. Crews*, P. DeFur*, S. Dickerson, T. Edwards* ...

co-author countries: Canada 🇨🇦 United States of America 🇺🇸
Source: Crossref
Added: September 8, 2020

2013 journal article

Designing endocrine disruption out of the next generation of chemicals

Green Chemistry, 15(1), 181–198.

By: T. Schug, R. Abagyan, B. Blumberg, T. Collins, D. Crews, P. DeFur, S. Dickerson, T. Edwards ...

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Effects of environmental endocrine disruptors and phytoestrogens on the Kisspeptin system

Kisspeptin Signaling in Reproductive Biology, 784, 455–479.

By: H. Patisaul

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Prenatal Bisphenol A Exposure Alters Sex-Specific Estrogen Receptor Expression in the Neonatal Rat Hypothalamus and Amygdala

TOXICOLOGICAL SCIENCES, 133(1), 157–173.

By: J. Cao n, M. Rebuli n, J. Rogers n, K. Todd n, S. Leyrer n, S. Ferguson*, H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: brain; endocrine disruptor; endocrine disruption; hypothalamus; development; sexually dimorphic; ethinyl estradiol
MeSH headings : Amygdala / drug effects; Amygdala / growth & development; Amygdala / metabolism; Animals; Animals, Newborn; Benzhydryl Compounds / toxicity; Dose-Response Relationship, Drug; Endocrine Disruptors / toxicity; Estrogen Receptor alpha / genetics; Estrogen Receptor beta / genetics; Female; Gene Expression Regulation, Developmental / drug effects; Hypothalamus / drug effects; Hypothalamus / growth & development; Hypothalamus / metabolism; Male; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Prenatal Exposure Delayed Effects / genetics; Prenatal Exposure Delayed Effects / metabolism; Rats; Rats, Sprague-Dawley; Receptors, Estrogen / genetics; Sex Factors
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Sex specific impact of perinatal bisphenol A (BPA) exposure over a range of orally administered doses on rat hypothalamic sexual differentiation

NEUROTOXICOLOGY, 36, 55–62.

By: K. McCaffrey n, B. Jones*, N. Mabrey n, B. Weiss*, S. Swan* & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Endocrine disruption; Estrogen; Hypothalamus; Sexually dimorphic; Dopamine
MeSH headings : Administration, Oral; Air Pollutants, Occupational / toxicity; Analysis of Variance; Animals; Benzhydryl Compounds / administration & dosage; Benzhydryl Compounds / toxicity; Calbindins / metabolism; Cell Count; Dose-Response Relationship, Drug; Female; Hypothalamus / drug effects; Hypothalamus / metabolism; Male; Phenols / administration & dosage; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Rats; Rats, Long-Evans; Sex Differentiation / physiology; Tyrosine 3-Monooxygenase / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Accumulation and Endocrine Disrupting Effects of the Flame Retardant Mixture Firemaster®550 in Rats: An Exploratory Assessment

Journal of Biochemical and Molecular Toxicology, 27(2), 124–136.

By: H. Patisaul n, S. Roberts*, N. Mabrey n, K. McCaffrey n, R. Gear*, J. Braun*, S. Belcher*, H. Stapleton*

co-author countries: United States of America 🇺🇸

Contributors: H. Patisaul n, S. Roberts*, N. Mabrey n, K. Mccaffrey n, R. Gear*, J. Braun*, S. Belcher*, H. Stapleton*

author keywords: Anxiety; Cardiac Hypertrophy; Endocrine Disruptor; Flame Retardants; Metabolic Syndrome; Metabolism; Obesity; Obesogen; Polybrominated Diphenyl Ethers; Rodents
MeSH headings : Animals; Cardiomegaly / blood; Cardiomegaly / chemically induced; Cardiomegaly / pathology; Endocrine System / metabolism; Endocrine System / pathology; Endocrine System / physiology; Female; Flame Retardants / adverse effects; Male; Maternal Exposure / adverse effects; Obesity / blood; Obesity / chemically induced; Obesity / pathology; Pregnancy; Prenatal Exposure Delayed Effects / blood; Prenatal Exposure Delayed Effects / pathology; Rats; Rats, Wistar; Thyroxine / blood
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2012 journal article

Anxiogenic Effects of Developmental Bisphenol A Exposure Are Associated with Gene Expression Changes in the Juvenile Rat Amygdala and Mitigated by Soy

PLOS ONE, 7(9).

By: H. Patisaul n, A. Sullivan n, M. Radford n, D. Walker*, H. Adewale n, B. Winnik*, J. Coughlin*, B. Buckley*, A. Gore*

co-author countries: United States of America 🇺🇸
MeSH headings : Amygdala / drug effects; Animals; Anxiety / chemically induced; Anxiety / etiology; Benzhydryl Compounds / adverse effects; Estrogen Receptor beta / metabolism; Female; Gene Expression Profiling; Genistein / pharmacology; Maternal Exposure; Phenols / adverse effects; Pregnancy; Pregnancy, Animal; Rats; Rats, Wistar; Receptors, Melanocortin / metabolism; Sex Characteristics; Soybeans / drug effects; Water / chemistry
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Disrupted Organization of RFamide Pathways in the Hypothalamus Is Associated with Advanced Puberty in Female Rats Neonatally Exposed to Bisphenol A

BIOLOGY OF REPRODUCTION, 87(2).

By: S. Losa-Ward n, K. Todd n, K. McCaffrey n, K. Tsutsui* & H. Patisaul n

co-author countries: Japan 🇯🇵 United States of America 🇺🇸
author keywords: endocrine disruptor; kisspeptin; puberty; RFRP
MeSH headings : Animals; Benzhydryl Compounds; Body Weight / drug effects; Estrogens, Non-Steroidal / toxicity; Female; Gonadotropin-Releasing Hormone / metabolism; Hypothalamus / drug effects; Kisspeptins / metabolism; Male; Neuropeptides / metabolism; Phenols / toxicity; Puberty, Precocious / blood; Puberty, Precocious / chemically induced; Rats; Rats, Transgenic; Rats, Wistar; Vagina / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 review

Endocrine Disrupters: A Review of Some Sources, Effects, and Mechanisms of Actions on Behaviour and Neuroendocrine Systems

[Review of ]. JOURNAL OF NEUROENDOCRINOLOGY, 24(1), 144–159.

By: C. Frye*, E. Bo*, G. Calamandrei*, L. Calza*, F. Dessi-Fulgheri, M. Fernandez*, L. Fusani*, O. Kah* ...

co-author countries: France 🇫🇷 Italy 🇮🇹 Poland 🇵🇱 United States of America 🇺🇸
author keywords: xenoestrogens; dichloro diphenyl trichloroethane; methoxychlor; biocides; tributyltin; bisphenol A; diethylstilbestrol; ethinylestradiol; phytoestrogens; aryl hydrocarbon receptor; the peroxisome proliferator-activated receptor; retinoid X receptor
MeSH headings : Animals; Behavior, Animal / drug effects; Benzhydryl Compounds; Brain / drug effects; Endocrine Disruptors / pharmacology; Environmental Pollutants / pharmacology; Humans; Phenols / pharmacology; Phytoestrogens / pharmacology; Puberty / drug effects; Reproduction / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 article

Infertility in the Southern White Rhino: Is Diet the Source of the Problem?

Patisaul, H. B. (2012, April). ENDOCRINOLOGY, Vol. 153, pp. 1568–1571.

By: H. Patisaul n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Coumestrol / pharmacology; Female; Humans; Isoflavones / pharmacology; Receptors, Estrogen / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2012 journal article

Influence of ERβ selective agonism during the neonatal period on the sexual differentiation of the rat hypothalamic-pituitary-gonadal (HPG) axis

Biology of Sex Differences, 3(1), 2.

By: H. Patisaul n, S. Losa-Ward n, K. Todd n, K. McCaffrey n & J. Mickens n

co-author countries: United States of America 🇺🇸
Sources: Crossref, ORCID
Added: August 18, 2019

2012 journal article

Neonatal Bisphenol A exposure alters sexually dimorphic gene expression in the postnatal rat hypothalamus

NeuroToxicology, 33(1), 23–36.

By: J. Cao n, J. Mickens n, K. McCaffrey n, S. Leyrer n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Kisspeptin; Estrogen receptor; Sexual differentiation; Development; Brain; Endocrine disruption
MeSH headings : Age Factors; Analysis of Variance; Animals; Animals, Newborn; Benzhydryl Compounds; Estrogen Receptor alpha / genetics; Estrogen Receptor alpha / metabolism; Estrogen Receptor beta / genetics; Estrogen Receptor beta / metabolism; Estrogens, Non-Steroidal / pharmacology; Female; Gene Expression Regulation, Developmental / drug effects; Hypothalamus / drug effects; Hypothalamus / growth & development; Hypothalamus / metabolism; Kisspeptins / genetics; Kisspeptins / metabolism; Male; Phenols / pharmacology; RNA, Messenger / metabolism; Rats; Rats, Long-Evans; Sex Characteristics
Sources: Crossref, ORCID
Added: August 18, 2019

2012 journal article

Reproductive consequences of developmental phytoestrogen exposure

REPRODUCTION, 143(3), 247–260.

By: W. Jefferson*, H. Patisaul* & C. Williams*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Child Development / drug effects; Diet; Humans; Infant; Infant Food / adverse effects; Infant Formula / chemistry; Infant, Newborn; Phytoestrogens / adverse effects; Phytoestrogens / pharmacology; Reproduction / drug effects; Reproduction / physiology
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2012 journal article

Sex-specific expression of estrogen receptors α and β and Kiss1 in the postnatal rat amygdala

Journal of Comparative Neurology, 521(2), 465–478.

By: J. Cao n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: development; kisspeptin; sexually dimorphic; hypothalamus; neonatal
MeSH headings : Amygdala / growth & development; Amygdala / metabolism; Animals; Animals, Newborn; Estrogen Receptor alpha / biosynthesis; Estrogen Receptor alpha / genetics; Estrogen Receptor beta / biosynthesis; Estrogen Receptor beta / genetics; Female; Hippocampus / metabolism; Image Processing, Computer-Assisted; In Situ Hybridization; Kisspeptins / biosynthesis; Kisspeptins / genetics; Male; Pregnancy; RNA, Messenger / biosynthesis; RNA, Messenger / genetics; Rats; Rats, Long-Evans; Sex Characteristics; Sexual Maturation
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2011 journal article

Aryl hydrocarbon receptor activation in lactotropes and gonadotropes interferes with estradiol-dependent and -independent preprolactin, glycoprotein alpha and luteinizing hormone beta gene expression

MOLECULAR AND CELLULAR ENDOCRINOLOGY, 333(2), 151–159.

By: J. Cao n, H. Patisaul n & S. Petersen*

co-author countries: United States of America 🇺🇸
author keywords: Dioxin; Ahr; Antiestrogen; Prl; LH; Estradiol
MeSH headings : Animals; Aryl Hydrocarbon Hydroxylases / genetics; Aryl Hydrocarbon Hydroxylases / metabolism; Cytochrome P-450 CYP1A1 / genetics; Cytochrome P-450 CYP1A1 / metabolism; Cytochrome P-450 CYP1A2 / genetics; Cytochrome P-450 CYP1A2 / metabolism; Cytochrome P-450 CYP1B1; Estradiol / pharmacology; Estrogen Receptor alpha / genetics; Estrogen Receptor alpha / metabolism; Female; Gene Expression Regulation / drug effects; Glycoprotein Hormones, alpha Subunit / genetics; Glycoprotein Hormones, alpha Subunit / metabolism; Gonadotrophs / cytology; Gonadotrophs / drug effects; Gonadotrophs / metabolism; Immunohistochemistry; In Situ Hybridization; Lactotrophs / cytology; Lactotrophs / drug effects; Lactotrophs / metabolism; Luteinizing Hormone, beta Subunit / genetics; Luteinizing Hormone, beta Subunit / metabolism; Pituitary Gland / cytology; Pituitary Gland / drug effects; Pituitary Gland / enzymology; Polychlorinated Dibenzodioxins / pharmacology; Prolactin / genetics; Prolactin / metabolism; Protein Precursors / genetics; Protein Precursors / metabolism; RNA, Messenger / genetics; RNA, Messenger / metabolism; Rats; Rats, Sprague-Dawley; Receptors, Aryl Hydrocarbon / genetics; Receptors, Aryl Hydrocarbon / metabolism
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Endocrine Disruption of Brain Sexual Differentiation by Developmental PCB Exposure

ENDOCRINOLOGY, 152(2), 581–594.

By: S. Dickerson*, S. Cunningham*, H. Patisaul n, M. Woller* & A. Gore*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Estrogen Receptor alpha / metabolism; Female; Gonadotropin-Releasing Hormone / metabolism; Immunohistochemistry; Insulin-Like Growth Factor I / genetics; Kisspeptins; Male; Neurosecretory Systems / drug effects; Polychlorinated Biphenyls / pharmacology; Polymerase Chain Reaction; Pregnancy; Preoptic Area; Proteins / metabolism; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Androgen / genetics; Receptors, N-Methyl-D-Aspartate / genetics; Sex Differentiation / drug effects; Transforming Growth Factor beta / genetics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Neonatal agonism of ERβ impairs male reproductive behavior and attractiveness

Hormones and Behavior, 60(2), 185–194.

By: A. Sullivan n, P. Hamilton n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Sex behavior; Endocrine disruptor; Genistein; Estrogen receptor; Partner preference; DPN; Estrogen; Masculinization; Virility; Soy
MeSH headings : Animals; Dose-Response Relationship, Drug; Estradiol / analogs & derivatives; Estradiol / pharmacology; Estrogen Receptor alpha / agonists; Estrogen Receptor alpha / metabolism; Estrogen Receptor beta / agonists; Estrogen Receptor beta / metabolism; Estrogens / pharmacology; Genistein / pharmacology; Male; Mating Preference, Animal / drug effects; Nitriles / pharmacology; Phenols / pharmacology; Phytoestrogens / pharmacology; Propionates / pharmacology; Pyrazoles / pharmacology; Rats; Rats, Long-Evans; Sexual Behavior, Animal / drug effects
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2011 journal article

Neonatal exposure to genistein adversely impacts the ontogeny of hypothalamic kisspeptin signaling pathways and ovarian development in the peripubertal female rat

REPRODUCTIVE TOXICOLOGY, 31(3), 280–289.

By: S. Losa n, K. Todd n, A. Sullivan n, J. Cao n, J. Mickens n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Soy; Estrogen; Phytoestrogens; Endocrine disruptors; Development; Reproductive; Fertility; Ovary
MeSH headings : Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus / drug effects; Arcuate Nucleus of Hypothalamus / metabolism; Arcuate Nucleus of Hypothalamus / pathology; Female; Gene Expression Regulation, Developmental / drug effects; Genistein / toxicity; Hypothalamus / drug effects; Hypothalamus / metabolism; Immunohistochemistry; In Situ Hybridization; Kisspeptins; Midline Thalamic Nuclei / drug effects; Midline Thalamic Nuclei / metabolism; Midline Thalamic Nuclei / pathology; Ovary / drug effects; Ovary / growth & development; Phytoestrogens / toxicity; Proteins / genetics; Proteins / metabolism; RNA, Messenger / analysis; Rats; Rats, Long-Evans; Rats, Wistar; Sex Factors; Sexual Maturation / drug effects; Sexual Maturation / physiology; Signal Transduction / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 article

On the Need for a National (US) Research Program to Elucidate the Potential Risks to Human Health and the Environment Posed by Contaminants of Emerging Concern

Novak, P. J., Arnold, W. A., Blazer, V. S., Halden, R. U., Klaper, R. D., Kolpin, D. W., … Swackhamer, D. L. (2011, May 1). ENVIRONMENTAL SCIENCE & TECHNOLOGY, Vol. 45, pp. 3829–3830.

By: P. Novak*, W. Arnold*, V. Blazer*, R. Halden*, R. Klaper*, D. Kolpin*, D. Kriebel*, N. Love* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Environmental Health / trends; Environmental Pollutants / adverse effects; Environmental Pollution / adverse effects; Humans; Public Health / trends; Research / trends; United States
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

Sexually dimorphic expression of hypothalamic estrogen receptors α and β and kiss1 in neonatal male and female rats

The Journal of Comparative Neurology, 519(15), 2954–2977.

By: J. Cao n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: development; anteroventral periventricular nucleus (AVPV); medial preoptic area (MPOA); arcuate nucleus (ARC); kisspeptin; sex differences
MeSH headings : Animals; Autoradiography; Estrogen Receptor alpha / genetics; Estrogen Receptor alpha / metabolism; Estrogen Receptor beta / genetics; Estrogen Receptor beta / metabolism; Female; Hypothalamus / anatomy & histology; Hypothalamus / metabolism; Kisspeptins / genetics; Kisspeptins / metabolism; Male; Neurons / cytology; Neurons / metabolism; Pregnancy; Rats; Sex Characteristics; Signal Transduction / physiology
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2011 journal article

The impact of neonatal bisphenol-A exposure on sexually dimorphic hypothalamic nuclei in the female rat

NEUROTOXICOLOGY, 32(1), 38–49.

By: H. Adewale n, K. Todd n, J. Mickens n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Xenoestrogen; Endocrine disruption; Brain; Sexual differentiation; Development; Estrogen receptor; Neuroendocrine
MeSH headings : Age Factors; Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus / drug effects; Arcuate Nucleus of Hypothalamus / growth & development; Benzhydryl Compounds; Body Weight / drug effects; Body Weight / physiology; Female; Phenols / toxicity; Preoptic Area / drug effects; Preoptic Area / growth & development; Rats; Rats, Long-Evans; Sex Characteristics; Sexual Behavior, Animal / drug effects; Sexual Behavior, Animal / physiology; Ventromedial Hypothalamic Nucleus / drug effects; Ventromedial Hypothalamic Nucleus / growth & development
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Assessing Risks from Bisphenol A Evaluating human health risks from endocrine disruptors' such as BPA is difficult, but animal studies suggest trouble is afoot

AMERICAN SCIENTIST, 98(1), 30–39.

By: H. Patisaul*

Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 article

Neuroendocrine disruption: Historical roots, current progress, questions for the future

Gore, A. C., & Patisaul, H. B. (2010, October). FRONTIERS IN NEUROENDOCRINOLOGY, Vol. 31, pp. 395–399.

By: A. Gore* & H. Patisaul n

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Endocrine Disruptors / history; Endocrine Disruptors / toxicity; Female; History, 20th Century; History, 21st Century; Humans; Male; Neurosecretory Systems / drug effects; Rats
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 review

The pros and cons of phytoestrogens

[Review of ]. FRONTIERS IN NEUROENDOCRINOLOGY, 31(4), 400–419.

By: H. Patisaul* & W. Jefferson

author keywords: Soy; Isoflavones; Genistein; Equol; Endocrine disruption; Estrogen; ER alpha; ER beta; Brain; Hypothalamus
MeSH headings : Animals; Brain / drug effects; Brain / growth & development; Breast Neoplasms / prevention & control; Diethylstilbestrol / adverse effects; Endocrine Disruptors / adverse effects; Endocrine Disruptors / pharmacology; Female; Genitalia / drug effects; Genitalia / growth & development; Heart Diseases / prevention & control; Humans; Male; Menopause / drug effects; Menstrual Cycle / drug effects; Mice; Osteoporosis / prevention & control; Phytoestrogens / adverse effects; Phytoestrogens / pharmacology; Puberty / drug effects; Rats; Sexual Behavior / drug effects; Soybean Proteins / adverse effects; Soybean Proteins / pharmacology
Sources: Web Of Science, ORCID
Added: August 6, 2018

2009 journal article

Impact of neonatal exposure to the ERα agonist PPT, bisphenol-A or phytoestrogens on hypothalamic kisspeptin fiber density in male and female rats

NeuroToxicology, 30(3), 350–357.

By: H. Patisaul n, K. Todd n, J. Mickens n & H. Adewale n

co-author countries: United States of America 🇺🇸
author keywords: Bisphenol; Phytoestrogens; Soy; Genistein; Equal; Gonadotropins; Development; Disruption; Estrogen; Estrogen receptor; GnRH; KISS
MeSH headings : Animals; Animals, Newborn; Benzhydryl Compounds; Estradiol / analogs & derivatives; Estradiol / pharmacology; Estrogen Receptor alpha / agonists; Female; Hypothalamus / anatomy & histology; Kisspeptins; Male; Nerve Fibers / drug effects; Nerve Fibers / metabolism; Ovariectomy; Phenols / pharmacology; Phytoestrogens / pharmacology; Progesterone / pharmacology; Proteins / metabolism; Pyrazoles / pharmacology; Rats; Rats, Long-Evans; Sex Characteristics
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Long-term effects of environmental endocrine disruptors on reproductive physiology and behavior

Frontiers in Behavioral Neuroscience, 3, 10.

By: H. Patisaul n & H. Adewale n

co-author countries: United States of America 🇺🇸
author keywords: bisphenol; genistein; soy; estrogen receptors; development; sexual differentiation
Sources: Crossref, ORCID
Added: August 25, 2019

2009 journal article

Neonatal Bisphenol-A Exposure Alters Rat Reproductive Development and Ovarian Morphology Without Impairing Activation of Gonadotropin-Releasing Hormone Neurons

BIOLOGY OF REPRODUCTION, 81(4), 690–699.

By: H. Adewale n, W. Jefferson*, R. Newbold* & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: AVPV; corpora lutea; development; disruption; endocrine disruptors; ER alpha; ESR1; estradiol; estradiol receptor; estrogen; estrogen receptor; GnRH; gonad; hypothalamus; lordosis; neuroendocrinology; ovary; PPT; puberty
MeSH headings : Animals; Animals, Newborn; Benzhydryl Compounds; Dose-Response Relationship, Drug; Estrogens, Non-Steroidal / administration & dosage; Estrogens, Non-Steroidal / toxicity; Estrous Cycle / drug effects; Female; Gonadotropin-Releasing Hormone / metabolism; Hypothalamus / drug effects; Hypothalamus / metabolism; Male; Neuroendocrine Cells / drug effects; Ovary / drug effects; Ovary / pathology; Phenols / administration & dosage; Phenols / toxicity; Proto-Oncogene Proteins c-fos / metabolism; Rats; Rats, Long-Evans; Sexual Behavior, Animal / drug effects; Sexual Maturation / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2009 journal article

Neonatal agonism of ERα masculinizes serotonergic (5-HT) projections to the female rat ventromedial nucleus of the hypothalamus (VMN) but does not impair lordosis

Behavioural Brain Research, 196(2), 317–322.

By: H. Patisaul n, H. Adewale n & J. Mickens n

co-author countries: United States of America 🇺🇸
author keywords: Estrogen; Development; Hypothalamus; Serotonin; Sex differences; Estrogen receptor; DPN; PPT
MeSH headings : Animals; Animals, Newborn / physiology; Estradiol / administration & dosage; Estradiol / pharmacology; Estrogen Receptor alpha / agonists; Estrogen Receptor alpha / physiology; Estrogen Receptor beta / agonists; Female; Male; Neural Pathways / physiology; Nitriles / pharmacology; Phenols / pharmacology; Propionates / pharmacology; Pyrazoles / pharmacology; Rats; Serotonin / physiology; Sex Characteristics; Sexual Behavior, Animal / physiology; Ventromedial Hypothalamic Nucleus / physiology
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Progesterone and medroxyprogesterone acetate differentially regulate α4 subunit expression of GABAA receptors in the CA1 hippocampus of female rats

Physiology & Behavior, 97(1), 58–61.

By: K. Pazol*, K. Northcutt*, H. Patisaul n, K. Wallen* & M. Wilson*

co-author countries: United States of America 🇺🇸
author keywords: Allopregnanolone; Neurosteroids; GABA(A) receptors
MeSH headings : Animals; Drug Interactions; Estradiol / administration & dosage; Estradiol / analogs & derivatives; Female; Hippocampus / drug effects; Hippocampus / metabolism; Medroxyprogesterone Acetate / administration & dosage; Medroxyprogesterone Acetate / pharmacology; Ovariectomy; Progesterone / administration & dosage; Progesterone / pharmacology; RNA, Messenger / metabolism; Rats; Rats, Long-Evans; Receptors, GABA-A / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2009 journal article

Systemic administration of diarylpropionitrile (DPN) or phytoestrogens does not affect anxiety-related behaviors in gonadally intact male rats

HORMONES AND BEHAVIOR, 55(2), 319–328.

By: H. Patisaul n, K. Burke n, R. Hinkle n, H. Adewale n & D. Shea n

co-author countries: United States of America 🇺🇸

Contributors: H. Patisaul n, K. Burke n, R. Hinkle n, H. Adewale n & D. Shea n

author keywords: DPN; PPT; Estrogen; Soy isoflavones; Testosterone; Anxiety; Endocrine active compound; Resveratrol; Equol; Plus maze; ER beta; Estrogen receptor beta
MeSH headings : Analysis of Variance; Animals; Anti-Anxiety Agents / administration & dosage; Anxiety / drug therapy; Behavior, Animal / drug effects; Equol; Estrogen Receptor alpha / agonists; Isoflavones / administration & dosage; Male; Nitriles / administration & dosage; Nitriles / blood; Phenols; Phytoestrogens / administration & dosage; Propionates / administration & dosage; Propionates / blood; Pyrazoles / administration & dosage; Rats; Rats, Long-Evans; Rats, Wistar; Resveratrol; Stilbenes / administration & dosage; Testosterone / blood
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 review

Disrupted female reproductive physiology following neonatal exposure to phytoestrogens or estrogen specific ligands is associated with decreased GnRH activation and kisspeptin fiber density in the hypothalamus

[Review of ]. NEUROTOXICOLOGY, 29(6), 988–997.

By: H. Bateman n & H. Patisaul n

co-author countries: United States of America 🇺🇸
author keywords: Genistein; Equal; Soy; Isoflavones; Gonadotropin; Puberty; Development; Endocrine disruption; DPN; PPT
MeSH headings : Analysis of Variance; Animals; Animals, Newborn; Estradiol / analogs & derivatives; Estradiol / pharmacology; Estrous Cycle / drug effects; Female; Gonadotropin-Releasing Hormone / metabolism; Hypothalamus / drug effects; Kisspeptins; Nerve Fibers / metabolism; Phenols / pharmacology; Proteins / metabolism; Pyrazoles / pharmacology; Rats; Receptors, Estrogen / agonists; Reproductive Physiological Phenomena / drug effects
Sources: Web Of Science, ORCID
Added: August 6, 2018

2008 journal article

Influence of endocrine active compounds on the developing rodent brain

Brain Research Reviews, 57(2), 352–362.

By: H. Patisaul n & E. Polston*

co-author countries: United States of America 🇺🇸
author keywords: hypothalamus; estrogen receptor; development; sexually dimorphic; phytoestrogen; genistein; bisphenol
MeSH headings : Animals; Benzhydryl Compounds; Brain / drug effects; Brain / growth & development; Brain / pathology; Endocrine Disruptors / toxicity; Estrogens, Non-Steroidal / toxicity; Female; Genistein / toxicity; Male; Mice; Phenols / toxicity; Protein Kinase Inhibitors / toxicity; Rats; Sex Characteristics
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2008 journal article

Neonatal exposure to endocrine active compounds or an ERβ agonist increases adult anxiety and aggression in gonadally intact male rats

Hormones and Behavior, 53(4), 580–588.

By: H. Patisaul n & H. Bateman n

co-author countries: United States of America 🇺🇸
author keywords: DPN; PPT; bisphenol; equol; estrogen; phytoestrogens; soy isoflavones; EAC; endocrine disruptors
MeSH headings : Age Factors; Aggression / drug effects; Aggression / physiology; Analysis of Variance; Animals; Animals, Newborn; Anxiety / metabolism; Benzhydryl Compounds; Endocrine Disruptors / pharmacology; Equol; Estrogen Receptor alpha / agonists; Estrogen Receptor alpha / metabolism; Estrogen Receptor beta / agonists; Estrogen Receptor beta / drug effects; Estrogen Receptor beta / metabolism; Isoflavones / pharmacology; Male; Nitriles / pharmacology; Phenols / pharmacology; Propionates / pharmacology; Pyrazoles / pharmacology; Rats; Rats, Long-Evans; Statistics, Nonparametric; Testis / drug effects; Testis / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2008 journal article

Sex Differences in Serotonergic But Not γ-Aminobutyric Acidergic (GABA) Projections to the Rat Ventromedial Nucleus of the Hypothalamus

Endocrinology, 149(1), 397–408.

By: H. Patisaul n, A. Fortino* & E. Polston*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Animals, Newborn; Arcuate Nucleus of Hypothalamus / metabolism; Dorsomedial Hypothalamic Nucleus / metabolism; Estradiol / pharmacology; Female; Genistein / pharmacology; Glutamate Decarboxylase / metabolism; Male; Neurons, Afferent / drug effects; Neurons, Afferent / metabolism; Neurons, Afferent / physiology; Posture / physiology; Rats; Rats, Sprague-Dawley; Serotonin / metabolism; Sex Characteristics; Sexual Behavior, Animal / drug effects; Sexual Behavior, Animal / physiology; Ventromedial Hypothalamic Nucleus / drug effects; Ventromedial Hypothalamic Nucleus / metabolism; Ventromedial Hypothalamic Nucleus / physiology; gamma-Aminobutyric Acid / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2007 journal article

Differential disruption of nuclear volume and neuronal phenotype in the preoptic area by neonatal exposure to genistein and bisphenol-A

NEUROTOXICOLOGY, 28(1), 1–12.

By: H. Patisaul n, A. Fortino & E. Polston*

co-author countries: United States of America 🇺🇸
author keywords: AVPV; SDN; calbindin; estrogen; development; endocrine disruptor
MeSH headings : Animals; Animals, Newborn / physiology; Benzhydryl Compounds; Biomarkers; Calbindins; Estrogens, Non-Steroidal / toxicity; Female; Genistein / toxicity; Immunohistochemistry; Neurons / drug effects; Neurons / pathology; Oncogene Proteins v-fos / metabolism; Orchiectomy; Paraventricular Hypothalamic Nucleus / anatomy & histology; Paraventricular Hypothalamic Nucleus / drug effects; Paraventricular Hypothalamic Nucleus / growth & development; Phenols / toxicity; Phenotype; Pregnancy; Preoptic Area / anatomy & histology; Preoptic Area / drug effects; Preoptic Area / growth & development; Rats; Rats, Sprague-Dawley; Receptors, LHRH / drug effects; Receptors, LHRH / metabolism; S100 Calcium Binding Protein G / metabolism; Sex Characteristics
Sources: Web Of Science, ORCID
Added: August 6, 2018

2006 journal article

Neonatal genistein or bisphenol-A exposure alters sexual differentiation of the AVPV☆

Neurotoxicology and Teratology, 28(1), 111–118.

By: H. Patisaul*, A. Fortino & E. Polston

author keywords: phytoestrogens; ER alpha; tyrosine hydroxylase; rat; development; hypothalamus
MeSH headings : Animals; Animals, Newborn; Benzhydryl Compounds; Cell Count; Cell Differentiation / drug effects; Cell Differentiation / physiology; Disease Models, Animal; Estradiol / metabolism; Estradiol / pharmacology; Estradiol Congeners / toxicity; Estrogen Receptor alpha / drug effects; Estrogen Receptor alpha / metabolism; Estrogens, Non-Steroidal / adverse effects; Female; Genistein / toxicity; Growth Inhibitors / toxicity; Male; Nervous System Malformations / chemically induced; Nervous System Malformations / pathology; Nervous System Malformations / physiopathology; Phenols / toxicity; Pregnancy; Preoptic Area / abnormalities; Preoptic Area / drug effects; Preoptic Area / physiopathology; Rats; Rats, Sprague-Dawley; Sex Characteristics; Sex Differentiation / drug effects; Sex Differentiation / physiology; Tyrosine 3-Monooxygenase / drug effects; Tyrosine 3-Monooxygenase / metabolism
Sources: Crossref, ORCID
Added: August 18, 2019

2005 journal article

Dietary Soy Supplements Produce Opposite Effects on Anxiety in Intact Male and Female Rats in the Elevated Plus-Maze.

Behavioral Neuroscience, 119(2), 587–594.

By: H. Patisaul*, A. Blum*, J. Luskin* & M. Wilson*

co-author countries: United States of America 🇺🇸
author keywords: phytoestrogens; soy; stress; estrogen; endocrine disruptors
MeSH headings : Animals; Anxiety; Dietary Supplements; Estrus; Female; Male; Maze Learning; Phytoestrogens / pharmacology; Rats; Rats, Long-Evans; Sex Factors; Soybean Proteins / pharmacology
Sources: Crossref, ORCID
Added: August 18, 2019

2005 journal article

Phytoestrogen Action in the Adult and Developing Brain

Journal of Neuroendocrinology, 17(1), 57–64.

By: H. Patisaul*

author keywords: soy; phytoestrogens; coumestrol; isoflavones; genistein; daidzein; endocrine disrupters; oestrogen; sex behaviour; ER alpha; ER beta; brain; hypothalamus
MeSH headings : Adult; Animals; Brain / drug effects; Brain / growth & development; Dietary Supplements; Humans; Infant; Phytoestrogens / administration & dosage; Phytoestrogens / chemistry; Soy Foods
Sources: Crossref, ORCID
Added: August 18, 2019

2004 journal article

A soy supplement and tamoxifen inhibit sexual behavior in female rats

Hormones and Behavior, 45(4), 270–277.

By: H. Patisaul*, J. Luskin* & M. Wilson*

co-author countries: United States of America 🇺🇸
author keywords: pacing; lordosis; soy; isoflavone; phytoestrogen; SERM; sex
MeSH headings : Analysis of Variance; Animals; Dietary Supplements; Drug Combinations; Estradiol / physiology; Estrogen Antagonists / pharmacology; Estrogens, Non-Steroidal / pharmacology; Female; Genistein / pharmacology; Isoflavones / pharmacology; Male; Posture; Progesterone / physiology; Rats; Rats, Long-Evans; Sexual Behavior, Animal / drug effects; Sexual Behavior, Animal / physiology; Soy Foods; Tamoxifen / pharmacology
Sources: Crossref, ORCID
Added: August 18, 2019

2004 chapter

Dietary Phytoestrogens

In Endocrine Disruptors (pp. 135–173).

By: H. Patisaul* & P. Whitten

Sources: Crossref, ORCID
Added: August 18, 2019

2003 journal article

Immediate and residual effects of tamoxifen and ethynylestradiol in the female rat hypothalamus

Brain Research, 978(1-2), 185–193.

By: H. Patisaul*, E. Aultman*, I. Bielsky*, L. Young* & M. Wilson*

co-author countries: United States of America 🇺🇸
author keywords: selective estrogen receptor modulator; ER beta; ER alpha; estrogen; hypothalamus; progesterone
MeSH headings : Animals; Autoradiography; Binding Sites; Drug Administration Schedule / veterinary; Estradiol Congeners / adverse effects; Estradiol Congeners / pharmacology; Estrogen Antagonists / adverse effects; Estrogen Antagonists / pharmacology; Ethinyl Estradiol / adverse effects; Ethinyl Estradiol / pharmacology; Fallopian Tubes / drug effects; Female; Gene Expression Regulation / drug effects; Hypothalamus / drug effects; Hypothalamus / metabolism; In Situ Hybridization; Organ Size / drug effects; RNA, Messenger / biosynthesis; Rats; Rats, Sprague-Dawley; Receptors, Oxytocin / genetics; Receptors, Oxytocin / metabolism; Receptors, Progesterone / genetics; Receptors, Progesterone / metabolism; Reverse Transcriptase Polymerase Chain Reaction / methods; Tamoxifen / adverse effects; Tamoxifen / pharmacology; Time Factors; Vasotocin / analogs & derivatives; Vasotocin / pharmacokinetics
Sources: Crossref, ORCID
Added: August 18, 2019

2003 journal article

Oxytocin, But Not Oxytocin Receptor, is Regulated by Oestrogen Receptor β in the Female Mouse Hypothalamus

Journal of Neuroendocrinology, 15(8), 787–793.

By: H. Patisaul*, E. Scordalakes*, L. Young* & E. Rissman*

co-author countries: United States of America 🇺🇸
author keywords: oestrogen; ER beta; paraventricular nucleus; supraoptic nucleus; ER alpha
MeSH headings : Animals; Autoradiography; Estrogen Receptor beta; Estrogens / pharmacology; Female; Gene Expression / drug effects; Gene Expression / physiology; Hypothalamus, Anterior / metabolism; Immunohistochemistry; In Situ Hybridization; Mice; Mice, Inbred C57BL; Mice, Knockout; Ovariectomy; Oxytocin / genetics; Oxytocin / metabolism; Paraventricular Hypothalamic Nucleus / metabolism; Progesterone / pharmacology; Receptors, Estrogen / genetics; Receptors, Estrogen / metabolism; Receptors, Oxytocin / metabolism; Vasopressins / genetics; Vasopressins / metabolism
Sources: Crossref, ORCID
Added: August 18, 2019

2002 journal article

Genistein Affects ERβ- But Not ERα-Dependent Gene Expression in the Hypothalamus

Endocrinology, 143(6), 2189–2197.

By: H. Patisaul*, M. Melby, P. Whitten & L. Young

MeSH headings : Animals; Autoradiography; Brain Chemistry / drug effects; Diet; Estrogen Receptor alpha; Estrogen Receptor beta; Estrogens / blood; Estrogens, Non-Steroidal / blood; Estrogens, Non-Steroidal / pharmacology; Female; Gene Expression Regulation / drug effects; Genistein / blood; Genistein / pharmacology; Hypothalamus / drug effects; Hypothalamus / metabolism; In Situ Hybridization; Male; RNA, Messenger / biosynthesis; Radioimmunoassay; Rats; Rats, Long-Evans; Receptors, Estrogen / biosynthesis; Receptors, Estrogen / genetics; Receptors, Oxytocin / drug effects; Receptors, Oxytocin / metabolism; Sexual Behavior, Animal / drug effects; Sexual Maturation / physiology; Uterus / drug effects; Uterus / growth & development
Sources: Crossref, ORCID
Added: August 18, 2019

2002 journal article

Neurobehavioral actions of coumestrol and related isoflavonoids in rodents

Neurotoxicology and Teratology, 24(1), 47–54.

By: P. Whitten*, H. Patisaul* & L. Young*

co-author countries: United States of America 🇺🇸
author keywords: phytoestrogens; coumestrol; isoflavones; genistein; daidzein; endocrine disrupters; estrogen; sex behavior; ER alpha; ER beta
MeSH headings : Animals; Animals, Suckling; Coumestrol / pharmacology; Estrogens, Non-Steroidal / pharmacology; Female; Gene Expression / drug effects; Isoflavones / pharmacology; Male; Mice; Rats; Receptors, Estrogen / genetics; Sexual Behavior, Animal / drug effects
Sources: Crossref, ORCID
Added: August 18, 2019

2001 journal article

Coumestrol Antagonizes Neuroendocrine Actions of Estrogen via the Estrogen Receptor α

Experimental Biology and Medicine, 226(4), 301–306.

By: D. Jacob*, J. Temple*, H. Patisaul*, L. Young* & E. Rissman*

co-author countries: United States of America 🇺🇸
author keywords: phytoestrogen; progesterone receptor; luteinizing hormone; nutrition; estrogen receptor beta
MeSH headings : Animals; Brain / drug effects; Brain / metabolism; Coumestrol / administration & dosage; Coumestrol / pharmacology; Drug Evaluation, Preclinical; Estradiol / administration & dosage; Estradiol / pharmacology; Estrogen Receptor alpha; Estrogens, Non-Steroidal / pharmacology; Female; Hypothalamus / drug effects; Hypothalamus / metabolism; Luteinizing Hormone / blood; Mice; Mice, Knockout; Ovariectomy; Receptors, Estrogen / antagonists & inhibitors; Receptors, Estrogen / deficiency; Receptors, Estrogen / genetics; Receptors, Progesterone / analysis
Sources: Crossref, ORCID
Added: August 18, 2019

2001 journal article

Cross-species and interassay comparisons of phytoestrogen action.

Environmental Health Perspectives, 109(suppl 1), 5–20.

By: P. Whitten* & H. Patisaul*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Biological Assay / methods; Bone Density / drug effects; Breast / drug effects; Breast / pathology; Cell Division / drug effects; Diet; Dose-Response Relationship, Drug; Endocrine System / drug effects; Estrogens / agonists; Humans; Hypothalamo-Hypophyseal System / drug effects; Plant Growth Regulators / pharmacology; Urogenital System / drug effects; Urogenital System / pathology
Sources: Crossref, ORCID
Added: August 18, 2019

2001 journal article

Soy Isoflavone Supplements Antagonize Reproductive Behavior and Estrogen Receptor α- and β-Dependent Gene Expression in the Brain*

Endocrinology, 142(7), 2946–2952.

By: H. Patisaul*, M. Dindo*, P. Whitten* & L. Young*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Brain / physiology; Chromatography, High Pressure Liquid; Estradiol / metabolism; Estrogen Receptor alpha; Estrogen Receptor beta; Female; Gene Expression / drug effects; Isoflavones / analysis; Isoflavones / pharmacology; Male; RNA, Messenger / metabolism; Rats; Rats, Long-Evans; Receptors, Estrogen / genetics; Receptors, Estrogen / physiology; Receptors, Oxytocin / metabolism; Sexual Behavior, Animal / drug effects; Soybeans / chemistry; Uterus / drug effects
Sources: Crossref, ORCID
Added: August 18, 2019

1999 journal article

Regulation of estrogen receptor beta mRNA in the brain: opposite effects of 17β-estradiol and the phytoestrogen, coumestrol

Molecular Brain Research, 67(1), 165–171.

By: H. Patisaul*, P. Whitten & L. Young

author keywords: paraventricular nucleus; 17 beta-estradiol; ER beta; phytoestrogen; endocrine disruptor
MeSH headings : Animals; Antisense Elements (Genetics); Brain Chemistry / drug effects; Coumestrol / pharmacology; Estradiol / pharmacology; Estrogens, Non-Steroidal / pharmacology; Female; Gene Expression / physiology; In Situ Hybridization; Isoflavones; Ovariectomy; Paraventricular Hypothalamic Nucleus / chemistry; Paraventricular Hypothalamic Nucleus / physiology; Phytoestrogens; Plant Preparations; RNA, Messenger / metabolism; Rats; Rats, Sprague-Dawley; Receptors, Estrogen / genetics; Septal Nuclei / chemistry; Septal Nuclei / physiology
Sources: Crossref, ORCID
Added: August 18, 2019

Employment

Updated: August 15th, 2019 13:31

Noth Carolina State University Raleigh, NC, US
Associate Dean for Research College of Sciences

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