Heather Patisaul

Siegler, P. N., Shaughnessy, E. K., Horman, B., Vierling, T. T., King, D. H., Patisaul, H. B., … Dudek, S. M. (2024). Identification of hippocampal area CA2 in hamster and vole brain. JOURNAL OF COMPARATIVE NEUROLOGY, 532(3). https://doi.org/10.1002/cne.25603

Schkoda, S., Horman, B., Witchey, S., Armour, G. S., Nelson, M., Gaeta, E., … Patisaul, H. B. (2024). Sex-specific effects on elements of the social brain neural network in Wistar rats from perinatal exposure to FireMaster 550 or its components. NEUROTOXICOLOGY, 105, 111–120. https://doi.org/10.1016/j.neuro.2024.09.001

Elliott, K. C., Patisaul, H. B., Sargis, R. M., & Vandenberg, L. N. (2024). Words Matter: Reflective Science Communication and Tradeoffs in Environmental Health Research. ENVIRONMENTAL HEALTH PERSPECTIVES, 132(10). https://doi.org/10.1289/EHP14527

Woodruff, T. J., Rayasam, S. D. G., Axelrad, D. A., Koman, P. D., Chartres, N., Bennett, D. H., … Zeise, L. (2023). A science-based agenda for health-protective chemical assessments and decisions: overview and consensus statement. ENVIRONMENTAL HEALTH, 21(SUPPL 1). https://doi.org/10.1186/s12940-022-00930-3

Maffini, M. V., Rayasam, S. D. G., Axelrad, D. A., Birnbaum, L. S., Cooper, C., Franjevic, S., … Woodruff, T. J. (2023). [Review of Advancing the science on chemical classes]. ENVIRONMENTAL HEALTH, 21(SUPPL 1). https://doi.org/10.1186/s12940-022-00919-y

Newell, A. J., & Patisaul, H. B. (2023). Developmental organophosphate flame retardant exposure disrupts adult hippocampal neurogenesis in Wistar rats. NEUROTOXICOLOGY, 99, 104–114. https://doi.org/10.1016/j.neuro.2023.09.009

Marinello, W. P., Gillera, S. E. A., Han, Y., Richardson, J. R., St Armour, G., Horman, B. M., & Patisaul, H. B. (2023). Gestational exposure to FireMaster® 550 (FM 550) disrupts the placenta-brain axis in a socially monogamous rodent species, the prairie vole (<i>Microtus ochrogaster</i>). MOLECULAR AND CELLULAR ENDOCRINOLOGY, 576. https://doi.org/10.1016/j.mce.2023.112041

Newell, A. J., Jima, D., Reading, B., & Patisaul, H. B. (2023, July 3). Machine learning reveals common transcriptomic signatures across rat brain and placenta following developmental organophosphate ester exposure. TOXICOLOGICAL SCIENCES, Vol. 7. https://doi.org/10.1093/toxsci/kfad062

Schkoda, S., Horman, B., Witchey, S. K., Jansson, A., Macari, S., & Patisaul, H. B. (2023). Skeletal effects following developmental flame-retardant exposure are specific to sex and chemical class in the adult Wistar rat. FRONTIERS IN TOXICOLOGY, 5. https://doi.org/10.3389/ftox.2023.1216388

Marinello, W. P., Gillera, S. E. A., Huang, L., Rollman, J., Reif, D. M., & Patisaul, H. B. (2023). Uncovering the common factors of chemical exposure and behavior: Evaluating behavioral effects across a testing battery using factor analysis. NEUROTOXICOLOGY, 99, 264–273. https://doi.org/10.1016/j.neuro.2023.10.012

Joglekar, R., Cauley, M., Lipsich, T., Corcoran, D. L., Patisaul, H. B., Levin, E. D., … Murphy, S. K. (2022). Developmental nicotine exposure and masculinization of the rat preoptic area. NEUROTOXICOLOGY, 89, 41–54. https://doi.org/10.1016/j.neuro.2022.01.005

Adibi, J. J., Christiansen, S., Fenton, S. E., Holloway, A., & Patisaul, H. B. (2022). Editorial: Women in developmental and reproductive toxicology: 2021. Frontiers in Toxicology, 4. https://doi.org/10.3389/ftox.2022.1026314

Marinello, W. P., Gillera, S. E. A., Fanning, M. J., Malinsky, L. B., Rhodes, C. L., Horman, B. M., & Patisaul, H. B. (2022). Effects of developmental exposure to FireMaster (R) 550 (FM 550) on microglia density, reactivity and morphology in a prosocial animal model. NEUROTOXICOLOGY, 91, 140–154. https://doi.org/10.1016/j.neuro.2022.04.015

Witchey, S. K., Doyle, M. G., Fredenburg, J. D., St Armour, G., Horman, B., Odenkirk, M. T., … Patisaul, H. B. (2022, September 8). Impacts of Gestational FireMaster 550 (FM 550) Exposure on the Neonatal Cortex are Sex Specific and Largely Attributable to the Organophosphate Esters. NEUROENDOCRINOLOGY, Vol. 9. https://doi.org/10.1159/000526959

Gillera, S. E. A., Marinello, W. P., Nelson, M. A., Horman, B. M., & Patisaul, H. B. (2022). Individual and Combined Effects of Paternal Deprivation and Developmental Exposure to Firemaster 550 on Socio-Emotional Behavior in Prairie Voles. TOXICS, 10(5). https://doi.org/10.3390/toxics10050268

Newell, A. J., Kapps, V. A., Cai, Y., Rai, M. R., St Armour, G., Horman, B. M., … Patisaul, H. B. (2023). Maternal organophosphate flame retardant exposure alters the developing mesencephalic dopamine system in fetal rat. TOXICOLOGICAL SCIENCES, 191(2), 357–373. https://doi.org/10.1093/toxsci/kfac137

Sombers, L. A., & Patisaul, H. B. (2022, August 3). Virtual Issue: Neurotoxicology. ACS CHEMICAL NEUROSCIENCE, Vol. 13, pp. 2238–2239. https://doi.org/10.1021/acschemneuro.2c00375

Patisaul, H. B., Behl, M., Birnbaum, L. S., Blum, A., Diamond, M. L., Fernandez, S. R., … Stapleton, H. M. (2021). Beyond Cholinesterase Inhibition: Developmental Neurotoxicity of Organophosphate Ester Flame Retardants and Plasticizers. ENVIRONMENTAL HEALTH PERSPECTIVES, 129(10). https://doi.org/10.1289/EHP9285

Patisaul, H. B. (2021). [Review of Endocrine disruption and reproductive disorders: impacts on sexually dimorphic neuroendocrine pathways]. REPRODUCTION, 162(5), F111–F130. https://doi.org/10.1530/REP-20-0596

Krentzel, A. A., Kimble, L. C., Dorris, D. M., Horman, B. M., Meitzen, J., & Patisaul, H. B. (2021). FireMaster (R) 550 (FM 550) exposure during the perinatal period impacts partner preference behavior and nucleus accumbens core medium spiny neuron electrophysiology in adult male and female prairie voles, Microtus ochrogaster. HORMONES AND BEHAVIOR, 134. https://doi.org/10.1016/j.yhbeh.2021.105019

Grebe, N. M., Sharma, A., Freeman, S. M., Palumbo, M. C., Patisaul, H. B., Bales, K. L., & Drea, C. M. (2021). Neural correlates of mating system diversity: oxytocin and vasopressin receptor distributions in monogamous and non-monogamous Eulemur. SCIENTIFIC REPORTS, 11(1). https://doi.org/10.1038/s41598-021-83342-6

Engel, S. M., Patisaul, H. B., Brody, C., Hauser, R., Zota, A. R., Bennet, D. H., … Whyatt, R. M. (2021). Neurotoxicity of Ortho-Phthalates: Recommendations for Critical Policy Reforms to Protect Brain Development in Children. AMERICAN JOURNAL OF PUBLIC HEALTH, 111(4), 687–695. https://doi.org/10.2105/AJPH.2020.306014

Gillera, S. E. A., Marinello, W. P., Cao, K. T., Horman, B. M., Stapleton, H. M., & Patisaul, H. B. (2021). Sex-specific Disruption of the Prairie Vole Hypothalamus by Developmental Exposure to a Flame Retardant Mixture. ENDOCRINOLOGY, 162(8). https://doi.org/10.1210/endocr/bqab100

Hudson, K. M., Shiver, E., Yu, J., Mehta, S., Jima, D. D., Kane, M. A., … Cowley, M. (2021). Transcriptomic, proteomic, and metabolomic analyses identify candidate pathways linking maternal cadmium exposure to altered neurodevelopment and behavior. SCIENTIFIC REPORTS, 11(1). https://doi.org/10.1038/s41598-021-95630-2

Pace, C. L., Horman, B., Patisaul, H., & Muddiman, D. C. (2020). Analysis of neurotransmitters in rat placenta exposed to flame retardants using IR-MALDESI mass spectrometry imaging. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 412(15), 3745–3752. https://doi.org/10.1007/s00216-020-02626-4

Heindel, J. J., Belcher, S., Flaws, J. A., Prins, G. S., Ho, S.-M., Mao, J., … Zoeller, R. T. (2020). Data integration, analysis, and interpretation of eight academic CLARITY-BPA studies. REPRODUCTIVE TOXICOLOGY, 98, 29–60. https://doi.org/10.1016/j.reprotox.2020.05.014

Macari, S., Rock, K. D., Santos, M. S., Lima, V. T. M., Szawka, R. E., Moss, J., … Patisaul, H. B. (2020). Developmental Exposure to the Flame Retardant Mixture Firemaster 550 Compromises Adult Bone Integrity in Male but not Female Rats. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 21(7). https://doi.org/10.3390/ijms21072553

Rock, K. D., St Armour, G., Horman, B., Phillips, A., Ruis, M., Stewart, A. K., … Patisaul, H. B. (2020). Effects of Prenatal Exposure to a Mixture of Organophosphhate Flame Ritardants on Placental Gene Expression and Serotonergic Innervaion in the Fetal Rat Brain. TOXICOLOGICAL SCIENCES, 176(1), 203–223. https://doi.org/10.1093/toxsci/kfaa046

Miller, C. K., Halbing, A. A., Patisaul, H. B., & Meitzen, J. (2021). Interactions of the estrous cycle, novelty, and light on female and male rat open field locomotor and anxiety-related behaviors. PHYSIOLOGY & BEHAVIOR, 228. https://doi.org/10.1016/j.physbeh.2020.113203

Levin, E. D., Dow-Edwards, D., & Patisaul, H. (2021). Introduction to sex differences in neurotoxic effects. NEUROTOXICOLOGY AND TERATOLOGY, Vol. 83. https://doi.org/10.1016/j.ntt.2020.106931

Krentzel, A. A., Proano, S., Patisaul, H. B., & Meitzen, J. (2020). Temporal and bidirectional influences of estradiol on voluntary wheel running in adult female and male rats. HORMONES AND BEHAVIOR, 120. https://doi.org/10.1016/j.yhbeh.2020.104694

Patisaul, H. B. (2020). [Review of Achieving CLARITY on bisphenol A, brain and behaviour]. JOURNAL OF NEUROENDOCRINOLOGY, 32(1). https://doi.org/10.1111/jne.12730

La Merrill, M. A., Vandenberg, L. N., Smith, M. T., Goodson, W., Browne, P., Patisaul, H. B., … Zoeller, R. T. (2020). Consensus on the key characteristics of endocrine-disrupting chemicals as a basis for hazard identification. NATURE REVIEWS ENDOCRINOLOGY, 16(1), 45–57. https://doi.org/10.1038/s41574-019-0273-8

Miller, C. K., Krentzel, A. A., Patisaul, H. B., & Meitzen, J. (2020). Metabotropic glutamate receptor subtype 5 (mGlu5) is necessary for estradiol mitigation of light-induced anxiety behavior in female rats. Physiology & Behavior, 214, 112770. https://doi.org/10.1016/j.physbeh.2019.112770

Ruis, M. T., Rock, K. D., Hall, S. M., Horman, B., Patisaul, H. B., & Stapleton, H. M. (2019). PBDEs Concentrate in the Fetal Portion of the Placenta: Implications for Thyroid Hormone Dysregulation. ENDOCRINOLOGY, 160(11), 2748–2758. https://doi.org/10.1210/en.2019-00463

Witchey, S. K., Fuchs, J., & Patisaul, H. B. (2019). Perinatal bisphenol A (BPA) exposure alters brain oxytocin receptor (OTR) expression in a sex- and region- specific manner: A CLARITY-BPA consortium follow-up study. NEUROTOXICOLOGY, 74, 139–148. https://doi.org/10.1016/j.neuro.2019.06.007

Rock, K. D., Gillera, S. E. A., Devarasetty, P., Horman, B., Knudsen, G., Birnbaum, L. S., … Patisaul, H. B. (2019). Sex-specific behavioral effects following developmental exposure to tetrabromobisphenol A (TBBPA) in Wistar rats. NeuroToxicology, 75, 136–147. https://doi.org/10.1016/j.neuro.2019.09.003

Vandenberg, L. N., Prins, G. S., Patisaul, H. B., & Zoeller, R. T. (2020). [Review of The Use and Misuse of Historical Controls in Regulatory Toxicology: Lessons from the CLARITY-BPA Study]. ENDOCRINOLOGY, 161(5). https://doi.org/10.1210/endocr/bqz014

Patisaul, H. B., Fenton, S. E., & Aylor, D. (2018). Animal models of endocrine disruption. Best Practice & Research Clinical Endocrinology & Metabolism, 32(3), 283–297. https://doi.org/10.1016/j.beem.2018.03.011

Prins, G. S., Patisaul, H. B., Belcher, S. M., & Vandenberg, L. N. (2018). CLARITY-BPA academic laboratory studies identify consistent low-dose Bisphenol A effects on multiple organ systems. Basic & Clinical Pharmacology & Toxicology, 10(S3), 14–31. https://doi.org/10.1111/bcpt.13125

Rock, K. D., Horman, B., Phillips, A. L., McRitchie, S. L., Watson, S., Deese-Spruill, J., … al. (2018). EDC IMPACT: Molecular effects of developmental FM 550 exposure in Wistar rat placenta and fetal forebrain. ENDOCRINE CONNECTIONS, 7(2), 305–324. https://doi.org/10.1530/ec-17-0373

Rock, K. D., & Patisaul, H. B. (2018). Environmental Mechanisms of Neurodevelopmental Toxicity. Current Environmental Health Reports, 5(1), 145–157. https://doi.org/10.1007/s40572-018-0185-0

Bagley, M. C., Ekelof, M., Rock, K., Patisaul, H., & Muddiman, D. C. (2018). IR-MALDESI mass spectrometry imaging of underivatized neurotransmitters in brain tissue of rats exposed to tetrabromobisphenol A. ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 410(30), 7979–7986. https://doi.org/10.1007/s00216-018-1420-0

Vogel, A. R., Patisaul, H. B., Arambula, S. E., Tiezzi, F., & McGraw, L. A. (2018). Individual Variation in Social Behaviours of Male Lab-reared Prairie voles (Microtus ochrogaster) is Non-heritable and Weakly Associated with V1aR Density. Scientific Reports, 8(1), 1396. https://doi.org/10.1038/s41598-018-19737-9

Barrett, E. S., & Patisaul, H. B. (2018, May). Introduction to the special issue on endocrine disrupting chemicals and behavior. HORMONES AND BEHAVIOR, Vol. 101, pp. 1–2. https://doi.org/10.1016/j.yhbeh.2018.05.009

Stetzik, L. A., Sullivan, A. W., Patisaul, H. B., & Cushing, B. S. (2018). Novel unconditioned prosocial behavior in prairie voles (Microtus ochrogaster) as a model for empathy. BMC Research Notes, 11(1). https://doi.org/10.1186/s13104-018-3934-0

Willett, J. A., Johnson, A. G., Vogel, A. R., Patisaul, H. B., McGraw, L. A., & Meitzen, J. (2018). Nucleus accumbens core medium spiny neuron electrophysiological properties and partner preference behavior in the adult male prairie vole, Microtus ochrogaster. Journal of Neurophysiology, 119(4), 1576–1588. https://doi.org/10.1152/jn.00737.2017

Wang, T., Pehrsson, E. C., Purushotham, D., Li, D., Zhuo, X., Zhang, B., … Tyson, F. L. (2018). The NIEHS TaRGET II Consortium and environmental epigenomics. Nature Biotechnology, 36(3), 225–227. https://doi.org/10.1038/NBT.4099

Wang, T., Pehrsson, E. C., Purushotham, D., Li, D. F., Zhuo, X. Y., Zhang, B., … Tsai, Z. T. Y. (2018). The NIEHS TaRGET II Consortium and environmental epigenomics.

Patisaul, H. B. (2017). Chemical Contributions to Neurodevelopmental Disorders. Policy Insights from the Behavioral and Brain Sciences, 4(2), 123–130. https://doi.org/10.1177/2372732217719909

Arambula, S. E., Fuchs, J., Cao, J., & Patisaul, H. B. (2017). Effects of perinatal bisphenol A exposure on the volume of sexually-dimorphic nuclei of juvenile rats: A CLARITY-SPA consortium study. NEUROTOXICOLOGY, 63, 33–42. https://doi.org/10.1016/j.neuro.2017.09.002

Patisaul, H. B. (2017). Endocrine Disruption of Vasopressin Systems and Related Behaviors. Frontiers in Endocrinology, 8. https://doi.org/10.3389/fendo.2017.00134

Barrett, E. S., & Patisaul, H. B. (2017, November). Endocrine disrupting chemicals and behavior: Re-evaluating the science at a critical turning point. HORMONES AND BEHAVIOR, Vol. 96, pp. A1–A6. https://doi.org/10.1016/j.yhbeh.2017.09.010

DeWitt, J. C., & Patisaul, H. B. (2018). Endocrine disruptors and the developing immune system. Current Opinion in Toxicology, 10, 31–36. https://doi.org/10.1016/J.COTOX.2017.12.005

Patisaul, H. B., Gore, A. C., & Crews, D. (2017). Environmental endocrine disruption of brain and behavior. Hormones, Brain and Behavior, Vol 5: Development of Hormone-Behavior Relationships, 3rd Edition, 63–88.

Webb, E., Moon, J., Dyrszka, L., Rodriguez, B., Cox, C., Patisaul, H., … London, E. (2018). [Review of Neurodevelopmental and neurological effects of chemicals associated with unconventional oil and natural gas operations and their potential effects on infants and children]. REVIEWS ON ENVIRONMENTAL HEALTH, 33(1), 3–29. https://doi.org/10.1515/reveh-2017-0008

Arambula, S. E., Jima, D., & Patisaul, H. B. (2018). Prenatal bisphenol A (BPA) exposure alters the transcriptome of the neonate rat amygdala in a sex-specific manner: a CLARITY-BPA consortium study. NEUROTOXICOLOGY, 65, 207–220. https://doi.org/10.1016/j.neuro.2017.10.005

Baldwin, K. R., Phillips, A. L., Horman, B., Arambula, S. E., Rebuli, M. E., Stapleton, H. M., & Patisaul, H. B. (2017). Sex Specific Placental Accumulation and Behavioral Effects of Developmental Firemaster 550 Exposure in Wistar Rats. SCIENTIFIC REPORTS, 7. https://doi.org/10.1038/s41598-017-07216-6

Patisaul, H. B. (2016). Endocrine disruption by dietary phyto-oestrogens: impact on dimorphic sexual systems and behaviours. Proceedings of the Nutrition Society, 76(2), 130–144. https://doi.org/10.1017/s0029665116000677

Arambula, S. E., Belcher, S. M., Planchart, A., Turner, S. D., & Patisaul, H. B. (2016). Impact of Low Dose Oral Exposure to Bisphenol A (BPA) on the Neonatal Rat Hypothalamic and Hippocampal Transcriptome: A CLARITY-BPA Consortium Study. Endocrinology, 157(10), 3856–3872. https://doi.org/10.1210/en.2016-1339

Hicks, K. D., Sullivan, A. W., Cao, J., Sluzas, E., Rebuli, M., & Patisaul, H. B. (2016). Interaction of bisphenol A (BPA) and soy phytoestrogens on sexually dimorphic sociosexual behaviors in male and female rats. HORMONES AND BEHAVIOR, 84, 121–126. https://doi.org/10.1016/j.yhbeh.2016.06.010

Rebuli, M. E., Gibson, P., Rhodes, C. L., Cushing, B. S., & Patisaul, H. B. (2016). Sex differences in microglial colonization and vulnerabilities to endocrine disruption in the social brain. GENERAL AND COMPARATIVE ENDOCRINOLOGY, 238, 39–46. https://doi.org/10.1016/j.ygcen.2016.04.018

Smith, S. K., Lee, C. A., Dausch, M. E., Horman, B. M., Patisaul, H. B., McCarty, G. S., & Sombers, L. A. (2017). Simultaneous Voltammetric Measurements of Glucose and Dopamine Demonstrate the Coupling of Glucose Availability with Increased Metabolic Demand in the Rat Striatum. ACS Chemical Neuroscience, 8(2), 272–280. https://doi.org/10.1021/acschemneuro.6b00363

Phillips, A. L., Chen, A., Rock, K. D., Horman, B., Patisaul, H. B., & Stapleton, H. M. (2016). Transplacental and Lactational Transfer of Firemaster (R) 550 Components in Dosed Wistar Rats. TOXICOLOGICAL SCIENCES, 153(2), 246–257. https://doi.org/10.1093/toxsci/kfw122

Rebuli, M. E., & Patisaul, H. B. (2016, June). Assessment of sex specific endocrine disrupting effects in the prenatal and pre-pubertal rodent brain. JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY, Vol. 160, pp. 148–159. https://doi.org/10.1016/j.jsbmb.2015.08.021

Veiga-Lopez, A., Pennathur, S., Kannan, K., Patisaul, H. B., Dolinoy, D. C., Zeng, L., & Padmanabhan, V. (2015). Impact of Gestational Bisphenol A on Oxidative Stress and Free Fatty Acids: Human Association and Interspecies Animal Testing Studies. ENDOCRINOLOGY, 156(3), 911–922. https://doi.org/10.1210/en.2014-1863

Rebuli, M. E., Camacho, L., Adonay, M. E., Reif, D. M., Aylor, D. L., & Patisaul, H. B. (2015). Impact of Low-Dose Oral Exposure to Bisphenol A (BPA) on Juvenile and Adult Rat Exploratory and Anxiety Behavior: A CLARITY-BPA Consortium Study. TOXICOLOGICAL SCIENCES, 148(2), 341–354. https://doi.org/10.1093/toxsci/kfv163

Cao, J., Echelberger, R., Liu, M., Sluzas, E., McCaffrey, K., Buckley, B., & Patisaul, H. B. (2015). Soy but not bisphenol A (BPA) or the phytoestrogen genistin alters developmental weight gain and food intake in pregnant rats and their offspring. REPRODUCTIVE TOXICOLOGY, 58, 282–294. https://doi.org/10.1016/j.reprotox.2015.07.077

Sullivan, A. W., Beach, E. C., Stetzik, L. A., Perry, A., Alyssa S. D'Addezio, Cushing, B. S., & Patisaul, H. B. (2014). A Novel Model for Neuroendocrine Toxicology: Neurobehavioral Effects of BPA Exposure in a Prosocial Species, the Prairie Vole (Microtus ochrogaster). ENDOCRINOLOGY, 155(10), 3867–3881. https://doi.org/10.1210/en.2014-1379

Belcher, S. M., Cookman, C. J., Patisaul, H. B., & Stapleton, H. M. (2014). In vitro assessment of human nuclear hormone receptor activity and cytotoxicity of the flame retardant mixture FM 550 and its triarylphosphate and brominated components. Toxicology Letters, 228(2), 93–102. https://doi.org/10.1016/j.toxlet.2014.04.017

Rebuli, M. E., Cao, J., Sluzas, E., Delclos, K. B., Camacho, L., Lewis, S. M., … Patisaul, H. B. (2014). Investigation of the Effects of Subchronic Low Dose Oral Exposure to Bisphenol A (BPA) and Ethinyl Estradiol (EE) on Estrogen Receptor Expression in the Juvenile and Adult Female Rat Hypothalamus. TOXICOLOGICAL SCIENCES, 140(1), 190–203. https://doi.org/10.1093/toxsci/kfu074

Patisaul, H. B., Mabrey, N., Adewale, H. B., & Sullivan, A. W. (2014). Soy but not bisphenol A (BPA) induces hallmarks of polycystic ovary syndrome (PCOS) and related metabolic co-morbidities in rats. REPRODUCTIVE TOXICOLOGY, 49, 209–218. https://doi.org/10.1016/j.reprotox.2014.09.003

Filer, D., Patisaul, H. B., Schug, T., Reif, D., & Thayer, K. (2014). Test driving ToxCast: endocrine profiling for 1858 chemicals included in phase II. CURRENT OPINION IN PHARMACOLOGY, 19, 145–152. https://doi.org/10.1016/j.coph.2014.09.021

Hoffman, K., Fang, M., Horman, B., Patisaul, H. B., Garantziotis, S., Birnbaum, L. S., & Stapleton, H. M. (2014). Urinary Tetrabromobenzoic Acid (TBBA) as a Biomarker of Exposure to the Flame Retardant Mixture Firemaster
            
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            550. Environmental Health Perspectives, 122(9), 963–969. https://doi.org/10.1289/ehp.1308028

Yeo, M., Patisaul, H., & Liedtke, W. (2013). Decoding the language of epigenetics during neural development is key for understanding development as well as developmental neurotoxicity. EPIGENETICS, 8(11), 1128–1132. https://doi.org/10.4161/epi.26406

Schug, T. T., Abagyan, R., Blumberg, B., Collins, T. J., Crews, D., DeFur, P. L., … Vandenberg, L. N. (2013). Designing endocrine disruption out of the next generation of chemicals. Green Chemistry, 15(1), 181–198.

Patisaul, H. B. (2013). Effects of environmental endocrine disruptors and phytoestrogens on the Kisspeptin system. Kisspeptin Signaling in Reproductive Biology, 784, 455–479.

Cao, J., Rebuli, M. E., Rogers, J., Todd, K. L., Leyrer, S. M., Ferguson, S. A., & Patisaul, H. B. (2013). Prenatal Bisphenol A Exposure Alters Sex-Specific Estrogen Receptor Expression in the Neonatal Rat Hypothalamus and Amygdala. TOXICOLOGICAL SCIENCES, 133(1), 157–173. https://doi.org/10.1093/toxsci/kft035

McCaffrey, K. A., Jones, B., Mabrey, N., Weiss, B., Swan, S. H., & Patisaul, H. B. (2013). Sex specific impact of perinatal bisphenol A (BPA) exposure over a range of orally administered doses on rat hypothalamic sexual differentiation. NEUROTOXICOLOGY, 36, 55–62. https://doi.org/10.1016/j.neuro.2013.03.001

Cao, J., Joyner, L., Mickens, J. A., Leyrer, S. M., & Patisaul, H. B. (2014, April). Sex-specific Esr2 mRNA expression in the rat hypothalamus and amygdala is altered by neonatal bisphenol A exposure. REPRODUCTION, Vol. 147, pp. 537–554. https://doi.org/10.1530/rep-13-0501

Patisaul, H. B., Roberts, S. C., Mabrey, N., McCaffrey, K. A., Gear, R. B., Braun, J., … Stapleton, H. M. (2012). Accumulation and Endocrine Disrupting Effects of the Flame Retardant Mixture Firemaster®550 in Rats: An Exploratory Assessment. Journal of Biochemical and Molecular Toxicology, 27(2), 124–136. https://doi.org/10.1002/jbt.21439

Patisaul, H. B., Sullivan, A. W., Radford, M. E., Walker, D. M., Adewale, H. B., Winnik, B., … Gore, A. C. (2012). Anxiogenic Effects of Developmental Bisphenol A Exposure Are Associated with Gene Expression Changes in the Juvenile Rat Amygdala and Mitigated by Soy. PLOS ONE, 7(9). https://doi.org/10.1371/journal.pone.0043890

Schug, T. T., Abagyan, R., Blumberg, B., Collins, T. J., Crews, D., DeFur, P. L., … Myers, J. P. (2013). Designing endocrine disruption out of the next generation of chemicals. Green Chem., 15(1), 181–198. https://doi.org/10.1039/c2gc35055f

Losa-Ward, S. M., Todd, K. L., McCaffrey, K. A., Tsutsui, K., & Patisaul, H. B. (2012). Disrupted Organization of RFamide Pathways in the Hypothalamus Is Associated with Advanced Puberty in Female Rats Neonatally Exposed to Bisphenol A. BIOLOGY OF REPRODUCTION, 87(2). https://doi.org/10.1095/biolreprod.112.100826

Patisaul, H. B. (2012, April). Infertility in the Southern White Rhino: Is Diet the Source of the Problem? ENDOCRINOLOGY, Vol. 153, pp. 1568–1571. https://doi.org/10.1210/en.2012-1008

Patisaul, H. B., Losa-Ward, S. M., Todd, K. L., McCaffrey, K. A., & Mickens, J. A. (2012). Influence of ERβ selective agonism during the neonatal period on the sexual differentiation of the rat hypothalamic-pituitary-gonadal (HPG) axis. Biology of Sex Differences, 3(1), 2. https://doi.org/10.1186/2042-6410-3-2

Jefferson, W. N., Patisaul, H. B., & Williams, C. J. (2012). Reproductive consequences of developmental phytoestrogen exposure. REPRODUCTION, 143(3), 247–260. https://doi.org/10.1530/rep-11-0369

Cao, J., & Patisaul, H. B. (2012). Sex-specific expression of estrogen receptors α and β and Kiss1 in the postnatal rat amygdala. Journal of Comparative Neurology, 521(2), 465–478. https://doi.org/10.1002/cne.23185

Frye, C. A., Bo, E., Calamandrei, G., Calza, L., Dessi-Fulgheri, F., Fernandez, M., … Panzica, G. C. (2012). [Review of Endocrine Disrupters: A Review of Some Sources, Effects, and Mechanisms of Actions on Behaviour and Neuroendocrine Systems]. JOURNAL OF NEUROENDOCRINOLOGY, 24(1), 144–159. https://doi.org/10.1111/j.1365-2826.2011.02229.x

Cao, J., Mickens, J. A., McCaffrey, K. A., Leyrer, S. M., & Patisaul, H. B. (2012). Neonatal Bisphenol A exposure alters sexually dimorphic gene expression in the postnatal rat hypothalamus. NeuroToxicology, 33(1), 23–36. https://doi.org/10.1016/j.neuro.2011.11.002

Sullivan, A. W., Hamilton, P., & Patisaul, H. B. (2011). Neonatal agonism of ERβ impairs male reproductive behavior and attractiveness. Hormones and Behavior, 60(2), 185–194. https://doi.org/10.1016/j.yhbeh.2011.04.006

Novak, P. J., Arnold, W. A., Blazer, V. S., Halden, R. U., Klaper, R. D., Kolpin, D. W., … Swackhamer, D. L. (2011, May 1). On the Need for a National (US) Research Program to Elucidate the Potential Risks to Human Health and the Environment Posed by Contaminants of Emerging Concern. ENVIRONMENTAL SCIENCE & TECHNOLOGY, Vol. 45, pp. 3829–3830. https://doi.org/10.1021/es200744f

Cao, J., & Patisaul, H. B. (2011). Sexually dimorphic expression of hypothalamic estrogen receptors α and β and kiss1 in neonatal male and female rats. The Journal of Comparative Neurology, 519(15), 2954–2977. https://doi.org/10.1002/cne.22648

Cao, J., Patisaul, H. B., & Petersen, S. L. (2011). Aryl hydrocarbon receptor activation in lactotropes and gonadotropes interferes with estradiol-dependent and -independent preprolactin, glycoprotein alpha and luteinizing hormone beta gene expression. MOLECULAR AND CELLULAR ENDOCRINOLOGY, 333(2), 151–159. https://doi.org/10.1016/j.mce.2010.12.027

Patisaul, H. (2010). Assessing Risks from Bisphenol A Evaluating human health risks from endocrine disruptors' such as BPA is difficult, but animal studies suggest trouble is afoot. AMERICAN SCIENTIST, 98(1), 30–39. https://doi.org/10.1511/2010.82.30

Dickerson, S. M., Cunningham, S. L., Patisaul, H. B., Woller, M. J., & Gore, A. C. (2011). Endocrine Disruption of Brain Sexual Differentiation by Developmental PCB Exposure. ENDOCRINOLOGY, 152(2), 581–594. https://doi.org/10.1210/en.2010-1103

Losa, S. M., Todd, K. L., Sullivan, A. W., Cao, J., Mickens, J. A., & Patisaul, H. B. (2011). Neonatal exposure to genistein adversely impacts the ontogeny of hypothalamic kisspeptin signaling pathways and ovarian development in the peripubertal female rat. REPRODUCTIVE TOXICOLOGY, 31(3), 280–289. https://doi.org/10.1016/j.reprotox.2010.10.002

Gore, A. C., & Patisaul, H. B. (2010, October). Neuroendocrine disruption: Historical roots, current progress, questions for the future. FRONTIERS IN NEUROENDOCRINOLOGY, Vol. 31, pp. 395–399. https://doi.org/10.1016/j.yfrne.2010.07.003

Adewale, H. B., Todd, K. L., Mickens, J. A., & Patisaul, H. B. (2011). The impact of neonatal bisphenol-A exposure on sexually dimorphic hypothalamic nuclei in the female rat. NEUROTOXICOLOGY, 32(1), 38–49. https://doi.org/10.1016/j.neuro.2010.07.008

Patisaul, H. B., & Jefferson, W. (2010). [Review of The pros and cons of phytoestrogens]. FRONTIERS IN NEUROENDOCRINOLOGY, 31(4), 400–419. https://doi.org/10.1016/j.yfrne.2010.03.003

Patisaul, H. B., Todd, K. L., Mickens, J. A., & Adewale, H. B. (2009). Impact of neonatal exposure to the ERα agonist PPT, bisphenol-A or phytoestrogens on hypothalamic kisspeptin fiber density in male and female rats. NeuroToxicology, 30(3), 350–357. https://doi.org/10.1016/j.neuro.2009.02.010

Patisaul, H. B., & Adewale, H. B. (2009). Long-term effects of environmental endocrine disruptors on reproductive physiology and behavior. Frontiers in Behavioral Neuroscience, 3, 10. https://doi.org/10.3389/neuro.08.010.2009

Adewale, H. B., Jefferson, W. N., Newbold, R. R., & Patisaul, H. B. (2009). Neonatal Bisphenol-A Exposure Alters Rat Reproductive Development and Ovarian Morphology Without Impairing Activation of Gonadotropin-Releasing Hormone Neurons. BIOLOGY OF REPRODUCTION, 81(4), 690–699. https://doi.org/10.1095/biolreprod.109.078261

Pazol, K., Northcutt, K. V., Patisaul, H. B., Wallen, K., & Wilson, M. E. (2009). Progesterone and medroxyprogesterone acetate differentially regulate α4 subunit expression of GABAA receptors in the CA1 hippocampus of female rats. Physiology & Behavior, 97(1), 58–61. https://doi.org/10.1016/j.physbeh.2009.01.021

Bateman, H. L., & Patisaul, H. B. (2008). [Review of Disrupted female reproductive physiology following neonatal exposure to phytoestrogens or estrogen specific ligands is associated with decreased GnRH activation and kisspeptin fiber density in the hypothalamus]. NEUROTOXICOLOGY, 29(6), 988–997. https://doi.org/10.1016/j.neuro.2008.06.008

Patisaul, H. B., Adewale, H. B., & Mickens, J. A. (2009). Neonatal agonism of ERα masculinizes serotonergic (5-HT) projections to the female rat ventromedial nucleus of the hypothalamus (VMN) but does not impair lordosis. Behavioural Brain Research, 196(2), 317–322. https://doi.org/10.1016/j.bbr.2008.09.026

Patisaul, H. B., & Bateman, H. L. (2008). Neonatal exposure to endocrine active compounds or an ERβ agonist increases adult anxiety and aggression in gonadally intact male rats. Hormones and Behavior, 53(4), 580–588. https://doi.org/10.1016/j.yhbeh.2008.01.008

Patisaul, H. B., Burke, K. T., Hinkle, R. E., Adewale, H. B., & Shea, D. (2009). Systemic administration of diarylpropionitrile (DPN) or phytoestrogens does not affect anxiety-related behaviors in gonadally intact male rats. HORMONES AND BEHAVIOR, 55(2), 319–328. https://doi.org/10.1016/j.yhbeh.2008.11.004

Patisaul, H. B., & Polston, E. K. (2008). Influence of endocrine active compounds on the developing rodent brain. Brain Research Reviews, 57(2), 352–362. https://doi.org/10.1016/j.brainresrev.2007.06.008

Patisaul, H. B., Fortino, A. E., & Polston, E. K. (2008). Sex Differences in Serotonergic But Not γ-Aminobutyric Acidergic (GABA) Projections to the Rat Ventromedial Nucleus of the Hypothalamus. Endocrinology, 149(1), 397–408. https://doi.org/10.1210/en.2007-0666

Patisaul, H. B., Fortino, A. E., & Polston, E. K. (2007). Differential disruption of nuclear volume and neuronal phenotype in the preoptic area by neonatal exposure to genistein and bisphenol-A. NEUROTOXICOLOGY, 28(1), 1–12. https://doi.org/10.1016/j.neuro.2006.10.001

Patisaul, H., Fortino, A., & Polston, E. (2006). Neonatal genistein or bisphenol-A exposure alters sexual differentiation of the AVPV☆. Neurotoxicology and Teratology, 28(1), 111–118. https://doi.org/10.1016/j.ntt.2005.11.004

Patisaul, H. B., Blum, A., Luskin, J. R., & Wilson, M. E. (2005). Dietary Soy Supplements Produce Opposite Effects on Anxiety in Intact Male and Female Rats in the Elevated Plus-Maze. Behavioral Neuroscience, 119(2), 587–594. https://doi.org/10.1037/0735-7044.119.2.587

Patisaul, H. B. (2005). Phytoestrogen Action in the Adult and Developing Brain. Journal of Neuroendocrinology, 17(1), 57–64. https://doi.org/10.1111/j.1365-2826.2005.01268.x

Patisaul, H. B., Luskin, J. R., & Wilson, M. E. (2004). A soy supplement and tamoxifen inhibit sexual behavior in female rats. Hormones and Behavior, 45(4), 270–277. https://doi.org/10.1016/j.yhbeh.2003.12.006

Patisaul, H. B., & Whitten, P. L. (2004). Dietary Phytoestrogens. In Endocrine Disruptors (pp. 135–173). https://doi.org/10.1201/9781420038866-5

Patisaul, H. B., Aultman, E. A., Bielsky, I. F., Young, L. J., & Wilson, M. E. (2003). Immediate and residual effects of tamoxifen and ethynylestradiol in the female rat hypothalamus. Brain Research, 978(1-2), 185–193. https://doi.org/10.1016/s0006-8993(03)02807-5

Patisaul, H. B., Scordalakes, E. M., Young, L. J., & Rissman, E. F. (2003). Oxytocin, But Not Oxytocin Receptor, is Regulated by Oestrogen Receptor β in the Female Mouse Hypothalamus. Journal of Neuroendocrinology, 15(8), 787–793. https://doi.org/10.1046/j.1365-2826.2003.01061.x

Patisaul, H. B., Melby, M., Whitten, P. L., & Young, L. J. (2002). Genistein Affects ERβ- But Not ERα-Dependent Gene Expression in the Hypothalamus. Endocrinology, 143(6), 2189–2197. https://doi.org/10.1210/endo.143.6.8843

Whitten, P. L., Patisaul, H. B., & Young, L. J. (2002). Neurobehavioral actions of coumestrol and related isoflavonoids in rodents. Neurotoxicology and Teratology, 24(1), 47–54. https://doi.org/10.1016/s0892-0362(01)00192-1

Jacob, D. A., Temple, J. L., Patisaul, H. B., Young, L. J., & Rissman, E. F. (2001). Coumestrol Antagonizes Neuroendocrine Actions of Estrogen via the Estrogen Receptor α. Experimental Biology and Medicine, 226(4), 301–306. https://doi.org/10.1177/153537020122600406

Whitten, P. L., & Patisaul, H. B. (2001). Cross-species and interassay comparisons of phytoestrogen action. Environmental Health Perspectives, 109(suppl 1), 5–20. https://doi.org/10.1289/ehp.01109s15

Patisaul, H. B., Dindo, M., Whitten, P. L., & Young, L. J. (2001). Soy Isoflavone Supplements Antagonize Reproductive Behavior and Estrogen Receptor α- and β-Dependent Gene Expression in the Brain*. Endocrinology, 142(7), 2946–2952. https://doi.org/10.1210/endo.142.7.8241

Patisaul, H. B., Whitten, P. L., & Young, L. J. (1999). Regulation of estrogen receptor beta mRNA in the brain: opposite effects of 17β-estradiol and the phytoestrogen, coumestrol. Molecular Brain Research, 67(1), 165–171. https://doi.org/10.1016/s0169-328x(99)00058-3