Halle Jiang Cantor

College of Veterinary Medicine

Works (8)

Updated: October 1st, 2024 05:02

2024 article

Clot-Targeted Nanogels for Dual-Delivery of AntithrombinIII and Tissue Plasminogen Activator to Mitigate Disseminated Intravascular Coagulation Complications

Sheridan, A., Nellenbach, K., Pandit, S., Byrnes, E., Hardy, G., Lutz, H., … Brown, A. C. (2024, June 5). ACS NANO, Vol. 6.

By: A. Sheridan n, K. Nellenbach n, S. Pandit n, E. Byrnes n, G. Hardy n, H. Lutz  n, N. Moiseiwitsch n, G. Scull n ...

author keywords: nanogel; fibrin; thrombosis; hemorrhage; fibrinolytic; anticoagulant
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: June 24, 2024

2024 journal article

Inhalable Stem Cell Exosomes Promote Heart Repair After Myocardial Infarction

CIRCULATION, 150(9), 710–723.

By: J. Li n, S. Sun *, D. Zhu* , X. Mei*, Y. Lyu n, K. Huang n , Y. Li n , S. Liu* ...

author keywords: CD36; extracellular vesicles; exosomes; inhalation; myocardial infarction
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3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 1, 2024

2022 article

Exosomes decorated with a recombinant SARS-CoV-2 receptor-binding domain as an inhalable COVID-19 vaccine

Wang, Z., Popowski, K. D., Zhu, D., Abad, B. L. de J., Wang, X., Liu, M., … Cheng, K. (2022, July 4). NATURE BIOMEDICAL ENGINEERING, Vol. 7.

By: Z. Wang n, K. Popowski n , D. Zhu n , B. Abad  n, X. Wang  n, M. Liu n, H. Lutz  n, N. De Naeyer* ...

MeSH headings : Animals; Antibodies, Neutralizing; CD8-Positive T-Lymphocytes; COVID-19 / prevention & control; COVID-19 Vaccines; Exosomes; Humans; Mice; Mice, Inbred BALB C; SARS-CoV-2; Viral Vaccines
TL;DR: The design and preclinical testing of an inhalable virus-like-particle as a COVID-19 vaccine that, after lyophilisation, is stable at room temperature for over three months and elicits systemic and mucosal immune responses in small animals is reported. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 11, 2022

2022 journal article

Inhalable dry powder mRNA vaccines based on extracellular vesicles

Matter, 5(9), 2960–2974.

By: K. Popowski n , A. Moatti n , G. Scull n, D. Silkstone n, H. Lutz  n, B. López de Juan Abad  n, A. George n , E. Belcher  n ...

TL;DR: The results suggest that extracellular vesicles can serve as an inhaled mRNA drug-delivery system that is superior to synthetic liposomes. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: October 17, 2022

2021 journal article

A stem cell-derived ovarian regenerative patch restores ovarian function and rescues fertility in rats with primary ovarian insufficiency

THERANOSTICS, 11(18), 8894–8908.

By: S. Zhang n, D. Zhu n , Z. Li n, K. Huang n , S. Hu n , H. Lutz  n, M. Xie n, X. Mei n ...

Contributors: S. Zhang n, D. Zhu n , Z. Li n, K. Huang n , S. Hu n , H. Lutz  n, M. Xie n, X. Mei n ...

author keywords: primary ovarian insufficiency; ovarian regenerative patch; regenerative medicine; mesenchymal stem cells; acellular therapy; fertility
MeSH headings : Animals; Apoptosis; Cell-Derived Microparticles / metabolism; Disease Models, Animal; Female; Hydrogels / pharmacology; Infertility, Female / therapy; Mesenchymal Stem Cell Transplantation / methods; Mesenchymal Stem Cells / metabolism; Ovary / pathology; Primary Ovarian Insufficiency / therapy; Rats; Rats, Sprague-Dawley; Regenerative Medicine / methods; Secretome; Stem Cells / metabolism; Tissue Scaffolds
TL;DR: In a rat model of POI, implantation of ORP rescued fertility by restoring sexual hormone secretion, estrus cycle duration, and follicle development and represents a cell-free, off-the-shelf, and clinically feasible treatment for POI. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: October 12, 2021

2021 review

Exosome therapeutics for COVID-19 and respiratory viruses

[Review of ]. VIEW, 2(3).

By: K. Popowski n , P. Dinh n, A. George n , H. Lutz  n & K. Cheng n

author keywords: COVID-19; exosomes; respiratory viruses; SARS-CoV-2
TL;DR: The relationship between exosomes and respiratory viruses is reviewed, potential exosome therapeutics for viral infections are described, and progress toward clinical translation for lung‐derived exosomal therapeutics is summarized. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: July 19, 2021

2020 journal article

Dermal exosomes containing miR-218-5p promote hair regeneration by regulating beta-catenin signaling

SCIENCE ADVANCES, 6(30).

By: S. Hu n , Z. Li n, H. Lutz  n, K. Huang n , T. Su n, J. Cores n, P. Dinh n, K. Cheng n

MeSH headings : Cells, Cultured; Exosomes; Hair; Hair Follicle; MicroRNAs / genetics; Regeneration; beta Catenin / genetics
TL;DR: Results revealed that DP spheroids are effective at inducing the progression of the hair follicle cycle from telogen to anagen compared with just DP cell or minoxidil treatment, and it was demonstrated that miR-218-5p was notably up-regulated in DP spheroid–derived exosomes. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 10, 2020

2020 review

Exosome therapeutics for lung regenerative medicine

[Review of ]. JOURNAL OF EXTRACELLULAR VESICLES, 9(1).

By: K. Popowski n , H. Lutz  n, S. Hu n , A. George n , P. Dinh n & K. Cheng n

author keywords: Exosome; regenerative medicine; lung spheroid cell; stem cell
TL;DR: The uses of exosomes as a therapy and their roles in lung regenerative medicine, as well as current challenges in exosome therapies are underline. (via Semantic Scholar)
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2. Zero Hunger (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 20, 2020

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