@article{lian_zeldes_lipscomb_hawkins_han_loder_nishiyama_adams_kelly_2016, title={Ancillary contributions of heterologous biotin protein ligase and carbonic anhydrase for CO2 incorporation into 3-hydroxypropionate by metabolically engineered Pyrococcus furiosus}, volume={113}, number={12}, journal={Biotechnology and Bioengineering}, author={Lian, H. and Zeldes, B. M. and Lipscomb, G. L. and Hawkins, A. B. and Han, Y. J. and Loder, A. J. and Nishiyama, D. and Adams, M. W. W. and Kelly, R. M.}, year={2016}, pages={2652–2660} }
 @article{loder_han_hawkins_lian_lipscomb_schut_keller_adams_kelly_2016, title={Reaction kinetic analysis of the 3-hydroxypropionate/4-hydroxybutyrate CO2 fixation cycle in extremely thermoacidophilic archaea}, volume={38}, ISSN={["1096-7184"]}, DOI={10.1016/j.ymben.2016.10.009}, abstractNote={The 3-hydroxypropionate/4-hydroxybutyrate (3HP/4HB) cycle fixes CO2 in extremely thermoacidophilic archaea and holds promise for metabolic engineering because of its thermostability and potentially rapid pathway kinetics. A reaction kinetics model was developed to examine the biological and biotechnological attributes of the 3HP/4HB cycle as it operates in Metallosphaera sedula, based on previous information as well as on kinetic parameters determined here for recombinant versions of five of the cycle enzymes (malonyl-CoA/succinyl-CoA reductase, 3-hydroxypropionyl-CoA synthetase, 3-hydroxypropionyl-CoA dehydratase, acryloyl-CoA reductase, and succinic semialdehyde reductase). The model correctly predicted previously observed features of the cycle: the 35–65% split of carbon flux through the acetyl-CoA and succinate branches, the high abundance and relative ratio of acetyl-CoA/propionyl-CoA carboxylase (ACC) and MCR, and the significance of ACC and hydroxybutyryl-CoA synthetase (HBCS) as regulated control points for the cycle. The model was then used to assess metabolic engineering strategies for incorporating CO2 into chemical intermediates and products of biotechnological importance: acetyl-CoA, succinate, and 3-hydroxypropionate.}, journal={METABOLIC ENGINEERING}, author={Loder, Andrew J. and Han, Yejun and Hawkins, Aaron B. and Lian, Hong and Lipscomb, Gina L. and Schut, Gerrit J. and Keller, Matthew W. and Adams, Michael W. W. and Kelly, Robert M.}, year={2016}, month={Nov}, pages={446–463} }
 @article{hawkins_lian_zeldes_loder_lipscomb_schut_keller_adams_kelly_2015, title={Bioprocessing analysis of Pyrococcus furiosus strains engineered for CO2-based 3-hydroxypropionate production}, volume={112}, ISSN={["1097-0290"]}, DOI={10.1002/bit.25584}, abstractNote={ABSTRACT}, number={8}, journal={BIOTECHNOLOGY AND BIOENGINEERING}, author={Hawkins, Aaron B. and Lian, Hong and Zeldes, Benjamin M. and Loder, Andrew J. and Lipscomb, Gina L. and Schut, Gerrit J. and Keller, Matthew W. and Adams, Michael W. W. and Kelly, Robert M.}, year={2015}, month={Aug}, pages={1533–1543} }
 @misc{hawkins_mcternan_lian_kelly_adams_2013, title={Biological conversion of carbon dioxide and hydrogen into liquid fuels and industrial chemicals}, volume={24}, ISSN={["1879-0429"]}, DOI={10.1016/j.copbio.2013.02.017}, abstractNote={Non-photosynthetic routes for biological fixation of carbon dioxide into valuable industrial chemical precursors and fuels are moving from concept to reality. The development of 'electrofuel'-producing microorganisms leverages techniques in synthetic biology, genetic and metabolic engineering, as well as systems-level multi-omic analysis, directed evolution, and in silico modeling. Electrofuel processes are being developed for a range of microorganisms and energy sources (e.g. hydrogen, formate, electricity) to produce a variety of target molecules (e.g. alcohols, terpenes, alkenes). This review examines the current landscape of electrofuel projects with a focus on hydrogen-utilizing organisms covering the biochemistry of hydrogenases and carbonic anhydrases, kinetic and energetic analyses of the known carbon fixation pathways, and the state of genetic systems for current and prospective electrofuel-producing microorganisms.}, number={3}, journal={CURRENT OPINION IN BIOTECHNOLOGY}, author={Hawkins, Aaron S. and McTernan, Patrick M. and Lian, Hong and Kelly, Robert M. and Adams, Michael W. W.}, year={2013}, month={Jun}, pages={376–384} }
 @article{hawkins_han_lian_loder_menon_iwuchukwu_keller_leuko_adams_kelly_2011, title={Extremely Thermophilic Routes to Microbial Electrofuels}, volume={1}, ISSN={["2155-5435"]}, DOI={10.1021/cs2003017}, abstractNote={ADVERTISEMENT RETURN TO ISSUEPREVViewpointNEXTExtremely Thermophilic Routes to Microbial ElectrofuelsAaron S. Hawkins†, Yejun Han†, Hong Lian†, Andrew J. Loder†, Angeli L. Menon‡, Ifeyinwa J. Iwuchukwu‡, Matthew Keller‡, Therese T. Leuko‡, Michael W.W. Adams‡, and Robert M. Kelly*†View Author Information† Department of Chemical and Biomolecular Engineering, North Carolina State University, Raleigh, North Carolina 27695-7905, United States‡ Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia 30602, United StatesPhone: (919) 515-6396. Fax: (919) 515-3465. E-mail: [email protected]Cite this: ACS Catal. 2011, 1, 9, 1043–1050Publication Date (Web):August 1, 2011Publication History Received7 June 2011Published online8 August 2011Published inissue 2 September 2011https://pubs.acs.org/doi/10.1021/cs2003017https://doi.org/10.1021/cs2003017editorialACS PublicationsCopyright © 2011 American Chemical Society. This publication is available under these Terms of Use. Request reuse permissions This publication is free to access through this site. Learn MoreArticle Views2851Altmetric-Citations36LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail PDF (3 MB) Get e-AlertscloseSUBJECTS:Bacteria,Genetics,Hydrogen,Oxides,Peptides and proteins Get e-Alerts}, number={9}, journal={ACS CATALYSIS}, author={Hawkins, Aaron S. and Han, Yejun and Lian, Hong and Loder, Andrew J. and Menon, Angeli L. and Iwuchukwu, Ifeyinwa J. and Keller, Matthew and Leuko, Therese T. and Adams, Michael W. W. and Kelly, Robert M.}, year={2011}, month={Sep}, pages={1043–1050} }