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Works (3)
Updated: June 29th, 2024 05:01
2024 article
Engineering Sclareol Production on the Leaf Surface of <i>Nicotiana tabacum</i>
Ma, H., Steede, T., Dewey, R. E., & Lewis, R. S. (2024, June 6). JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, Vol. 6.
author keywords: sclareol; terpene; terpenoid; metabolicengineering; tobacco; trichome; diterpenoid; leaf surface; secondary metabolite
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 24, 2024
2022 journal article
CLCNt2 Mediates Nitrate Content in Tobacco Leaf, Impacting the Production of Tobacco-Specific Nitrosamines in Cured Leaves
FRONTIERS IN PLANT SCIENCE, 13.
author keywords: CLCNt2; chloride channel; tobacco; NNN; NNK; nitrate transport; chloride; proton antiporters; tobacco-specific nitrosamines
TL;DR:
This study provides a straight path toward the development of new commercial tobacco varieties with reduced TSNA levels by breeding of variants deficient in active CLCNt2 copies byressing expression or knocking-out CLCnt2 has a direct impact on leaf nitrate and TSNA reduction in cured leaves without altering biomass.
(via Semantic Scholar)
open access via www.frontiersin.org (publisher PDF)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: March 14, 2022
2019 journal article
microRNA-21-5p dysregulation in exosomes derived from heart failure patients impairs regenerative potential
JOURNAL OF CLINICAL INVESTIGATION, 129(6), 2237–2250.
MeSH headings : Animals; Exosomes / genetics; Exosomes / metabolism; Exosomes / pathology; Female; Heart / physiology; Heart Failure / genetics; Heart Failure / metabolism; Heart Failure / pathology; Human Umbilical Vein Endothelial Cells / metabolism; Human Umbilical Vein Endothelial Cells / pathology; Humans; Male; Mice; MicroRNAs / genetics; MicroRNAs / metabolism; Myocardium / metabolism; Myocardium / pathology; Myocytes, Cardiac / metabolism; Myocytes, Cardiac / pathology; Neovascularization, Physiologic; Proto-Oncogene Proteins c-akt / genetics; Proto-Oncogene Proteins c-akt / metabolism; Regeneration; Signal Transduction; Stromal Cells / metabolism; Stromal Cells / pathology
TL;DR:
The heart failure pathological condition altered the miR cargos of cardiac-derived exosomes and impaired their regenerative activities, and mechanistic studies revealed that miR-21-5p augmented Akt kinase activity through the inhibition of phosphatase and tensin homolog.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: June 24, 2019
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