Works (165)
Updated: April 22nd, 2024 05:27
2024 article
Complete genome sequences of <i>Lactobacillus acidophilus</i> strain P42 and <i>Limosilactobacillus reuteri</i> strain P43 isolated from chicken cecum
Hassan, H. M., Mendoza, M., & Dickey, A. N. (2024, March 19). (J. C. D. Hotopp, Ed.). MICROBIOLOGY RESOURCE ANNOUNCEMENTS, Vol. 3.
Ed(s): J. Hotopp
author keywords: complete genome; PacBio HiFi reads; L. acidophilus P42; L. reuteriP43; poultry
TL;DR:
The complete circular genome sequences of Lactobacillus acidophilus strain P42 and Limosilactobacillus reuteri strain P43 isolated from chicken cecal samples are reported and could potentially serve as poultry probiotic strains.
(via Semantic Scholar)
doi.org (publisher)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: March 22, 2024
2024 journal article
In ovo feeding of probiotic lactobacilli differentially alters expression of genes involved in the development and immunological maturation of bursa of Fabricius in pre-hatched chicks
POULTRY SCIENCE, 103(1).
author keywords: chicken; probiotics; Lactobacillus; cytokine; bursa of Fabricius
Sources: Web Of Science, NC State University Libraries, ORCID
Added: January 2, 2024
2024 article
Modulation of functional activity of heat-stressed chicken macrophages by poultry-derived probiotic lactobacilli
Abdelaziz, K., Nixon, T., Joye, A., Hassan, H., Alizadeh, M., Sharif, S., & Kulkarni, R. R. (2024, April 9). CANADIAN JOURNAL OF ANIMAL SCIENCE, Vol. 4.
author keywords: chicken; Lactobacillus; macrophage; cytokine; TLR; heat stress
Sources: Web Of Science, NC State University Libraries
Added: April 15, 2024
2022 journal article
On 'Intracellular production of superoxide radical and of hydrogen peroxide by redox active compounds' by H. Moustafa Hassan, Irwin Fridovich
Archives of Biochemistry and Biophysics.
MeSH headings : Catalase / metabolism; Escherichia coli / metabolism; Free Radicals; Hydrogen Peroxide / pharmacology; Oxidation-Reduction; Oxygen; Superoxide Dismutase / metabolism; Superoxides
TL;DR:
This commentary discusses how the idea of employing redox cycling compounds to generate partially reduced oxygen species to cause oxidative stress in the model organism, Escherichia coli, was born.
(via Semantic Scholar)
Source: ORCID
Added: April 27, 2022
2021 journal article
Role of the Mn-Catalase in Aerobic Growth of Lactobacillus plantarum ATCC 14431
Applied Microbiology.
TL;DR:
The physiological role of Mn-catalase (MnKat) in Lactobacillus plantarum ATCC 14431 is investigated and showed that the MnKat is critical for aerobic growth, protection against H2O2, and maintenance of the rod-shaped cell morphology under aerobic conditions.
(via Semantic Scholar)
Source: ORCID
Added: December 21, 2021
2020 journal article
Attenuated Salmonella enterica Serovar Typhimurium, Strain NC983, Is Immunogenic, and Protective against Virulent Typhimurium Challenges in Mice
VACCINES, 8(4).
author keywords: Salmonella typhimurium; NC983; vaccine; in vivo; infection; C57BL/6 mice; BALB/c mice; IgG
TL;DR:
Oral delivery of strain NC983 was capable of fully protecting C57BL/6 and BALB/c mice against challenge with virulent Typhimurium, and results indicate that strainNC983 is a potential live attenuated vaccine strain that warrants further development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: January 19, 2021
2020 journal article
Complete Genome Sequences of Lactobacillus Strains C25 and P38, Isolated from Chicken Cecum
Microbiology Resource Announcements, 9(39).
Ed(s): D. Rasko
TL;DR:
The complete circular genome sequences of Lactobacillus crispatus strain C25, its plasmid, and LactOBacillus animalis strain P38; both strains were isolated from the cecum of 4-week-old chickens represent potential probiotic strains for poultry.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
15. Life on Land
(Web of Science)
Source: ORCID
Added: September 24, 2020
2020 journal article
Complete Genome Sequences of Six Lactobacilli Isolated from American Quarter Horses
MICROBIOLOGY RESOURCE ANNOUNCEMENTS, 9(47).
Ed(s): D. Rasko
TL;DR:
The complete circular genome sequences of six Lactobacillus strains and their plasmids, if any, from the fecal material of quarter horses at different ages are reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 4, 2021
2017 journal article
A comparison of sequencing platforms and bioinformatics pipelines for compositional analysis of the gut microbiome
BMC MICROBIOLOGY, 17.
author keywords: 16S rRNA amplicon sequencing; microbiome analysis; microbiome; microbiome composition; next generation sequencing platforms; Bioinformatics pipeline; NGS bias
MeSH headings : Analysis of Variance; Animals; Bacteria / classification; Bacteria / genetics; Base Sequence; Biodiversity; Cecum / microbiology; Chickens / microbiology; Computational Biology / instrumentation; Computational Biology / methods; DNA, Bacterial / analysis; DNA, Bacterial / genetics; DNA, Bacterial / isolation & purification; Gastrointestinal Microbiome / genetics; Gene Library; High-Throughput Nucleotide Sequencing / instrumentation; High-Throughput Nucleotide Sequencing / methods; Microbial Consortia / genetics; Multivariate Analysis; Phylogeny; RNA, Ribosomal, 16S / genetics; Reproducibility of Results; Statistics as Topic
TL;DR:
Overall microbiome compositional profiles were comparable between platforms; however, average relative abundance of specific taxa varied depending on sequencing platform, library preparation method, and bioinformatics analysis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2017 journal article
An Attenuated Salmonella enterica Serovar Typhimurium Strain and Galacto-Oligosaccharides Accelerate Clearance of Salmonella Infections in Poultry through Modifications to the Gut Microbiome
Applied and Environmental Microbiology, 84(5).
Ed(s): J. Schottel
author keywords: chicken gut microbiome; gut microbiome modulation; prebiotics
MeSH headings : Animals; Bacterial Vaccines / pharmacology; Chickens; Female; Gastrointestinal Microbiome / drug effects; Oligosaccharides / administration & dosage; Poultry Diseases / microbiology; Poultry Diseases / prevention & control; Prebiotics / administration & dosage; Random Allocation; Salmonella Infections, Animal / microbiology; Salmonella Infections, Animal / prevention & control; Salmonella typhimurium / immunology; Vaccines, Attenuated / pharmacology
TL;DR:
It is demonstrated that a manipulation of the chicken gut microbiota by the administration of an attenuated Salmonella strain or prebiotic galacto-oligosaccharides (GOS) can promote resistance to Salmonellosis via increases of beneficial microorganisms that translate into a less hospitable gut microenvironment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018
2017 journal article
Impact of Dietary Galacto-Oligosaccharide (GOS) on Chicken’s Gut Microbiota, Mucosal Gene Expression, and Salmonella Colonization
Frontiers in Veterinary Science, 4.
author keywords: chickens; immune; Salmonella; prebiotic; galacto-oligosaccharides
TL;DR:
Investigation of the effect of the prebiotic galacto-oligosaccharide (GOS) on the cecal microbiome and ultimately the carriage of Salmonella demonstrated that treatment with thePrebiotic GOS can modify both c Cecal tonsil gene expression and the cECal microbiome, suggesting that this type of treatment may be useful as a tool for altering the carriage in poultry.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries, ORCID
Added: December 19, 2018
2016 journal article
Complete Genome Sequence of NC983, a Live Attenuated Strain of Salmonella enterica Serovar Typhimurium
Genome Announcements, 4(5).
TL;DR:
The genome sequence of the nontyphoidal S. enterica serovar Typhimurium mutant strain NC983 is presented, a potential vaccine candidate, and a potential source of infection for Salmonella serovars.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: June 22, 2021
2016 report
Designer Probiotic Lactobacilli for use in Farm Animals and Methods for Enrichment and Isolation from any Animal Species or Human
(Invention Disclosure No. 17-063).
Source: NC State University Libraries
Added: March 12, 2022
2016 journal article
Development of the Chick Microbiome: How Early Exposure Influences Future Microbial Diversity
Frontiers in Veterinary Science, 3.
author keywords: chicken; microbiome development; Salmonella; probiotic; gut development
TL;DR:
Assessment of the development of the cecal microbiome in chicks from hatch to 28 days of age with and without a live Salmonella vaccine and/or probiotic supplement demonstrates that these live microbial treatments do impact theDevelopment of the bacterial taxa found in the growing chicks.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries, ORCID
Added: December 19, 2018
2016 journal article
Draft Genome Sequence of Lactobacillus crispatus C25 Isolated from Chicken Cecum
Genome Announcements, 4(6).
TL;DR:
The genome sequence of Lactobacillus crispatus strain C25, originally isolated from the cecum of 4-week-old chicken fed a standard diet, is presented, representing a potential probiotic strain for poultry.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries, ORCID
Added: December 19, 2018
2016 journal article
Draft Genome Sequences of Lactobacillus animalis Strain P38 and Lactobacillus reuteri Strain P43 Isolated from Chicken Cecum
Genome Announcements, 4(6).
TL;DR:
These indigenous Lactobacillus isolates are potential probiotic organisms for poultry after isolated from the cecum content of a 4-week old chicken fed a diet supplemented with the prebiotic β(1-4)galacto-oligosaccharide (GOS).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries, ORCID
Added: December 19, 2018
2016 report
Engineered Salmonella Serovar Typhimurium Strains, Compositions Thereof, and Methods of Use
(US Provisional Patent No. 62/368,507).
Source: NC State University Libraries
Added: August 28, 2021
2016 chapter
Interplay Between O2 and Iron in Gene Expression: Environmental Sensing by FNR, ArcA, and Fur in Bacteria
In F. J. de Bruijn (Ed.), Stress and Environmental Regulation of Gene Expression and Adaptation in Bacteria, I&II (pp. 1079–1089).
Ed(s): F. de Bruijn
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
2016 conference paper
The Chicken Gut Microbiome and Salmonella
Presented at the USDA-NIFA –Annual Program Directors Meeting, St. Louis, MO.
Event: USDA-NIFA –Annual Program Directors Meeting at St. Louis, MO on July 30, 2016
Source: NC State University Libraries
Added: August 13, 2021
2016 speech
Use of Probiotics and prebiotics in Poultry
Hassan, H. (2016, October). Presented at the Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China.
Event: at Institute of Animal Science, Chinese Academy of Agricultural Sciences, Beijing, China
Source: NC State University Libraries
Added: March 12, 2022
2016 report
Utilization of Hydroxyl Radicalfor Accelerated Shelf-life Testing
(Invention Disclosure No. 16-275).
Source: NC State University Libraries
Added: March 12, 2022
2015 journal article
Biology of reactive oxygen species, oxidative stress, and antioxidants in lactic acid bacteria
Probiotics and Prebiotics: Current Research and Future Trends, 205–218.
Contributors: M. Leite, B. Troxell, J. Bruno-Barcena* & *
Sources: NC State University Libraries, NC State University Libraries, ORCID
Added: August 6, 2018
2015 journal article
Mitochondrial DNA Fragmentation as a Molecular Tool to Monitor Thermal Processing of Plant-Derived, Low-Acid Foods, and Biomaterials
Journal of Food Science, 80(8), M1804–M1814.
author keywords: mitochondrial DNA; quantitative PCR; thermal processing
MeSH headings : Clostridium botulinum / isolation & purification; DNA Damage; DNA Fragmentation; DNA Primers; DNA, Mitochondrial / genetics; DNA, Mitochondrial / isolation & purification; DNA, Plant / genetics; DNA, Plant / isolation & purification; Food Contamination / analysis; Food Handling / methods; Food Microbiology; Fruit; Genes, Plant; Geobacillus stearothermophilus / isolation & purification; Hot Temperature; Ipomoea batatas / microbiology; Linear Models; Plant Proteins / genetics; Reproducibility of Results; Spores, Bacterial / isolation & purification; Vegetables
TL;DR:
Data is presented as proof-of-concept for a molecular tool that can be used as a rapid, presumptive method for monitoring thermal processing in low-acid plant products.
(via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2015 journal article
Mitochondrial DNA Fragmentation to Monitor Processing Parameters in High Acid, Plant-Derived Foods
Journal of Food Science, 80(12), M2892–M2898.
author keywords: high-acid foods; mitochondrial DNA; quantitative PCR; thermal processing
MeSH headings : Acids; Bacteria / growth & development; Cucumis sativus / genetics; DNA Fragmentation; DNA, Mitochondrial; DNA, Plant / analysis; Fermentation; Food Analysis; Food Handling / methods; Food Microbiology; Food Preservation / methods; Fruit; Genes, Mitochondrial; Genes, Plant; Humans; Hydrogen-Ion Concentration; Solanum lycopersicum / genetics; Pasteurization; Plants, Edible / genetics; Temperature; Vegetables
TL;DR:
MtDNA fragmentation was shown to be a potential new tool to characterize low temperature (<100 °C) high acid processes (pH < 4.6), nonthermal processes such as vegetable fermentation and holding times of acidified, plant-derived products.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2015 journal article
Poultry Body Temperature Contributes to Invasion Control through Reduced Expression of Salmonella Pathogenicity Island 1 Genes in Salmonella enterica Serovars Typhimurium and Enteritidis
Applied and Environmental Microbiology, 81(23), 8192–8201.
Contributors: B. Troxell n, N. Petri n, C. Daron n, R. Pereira *, M. Mendoza n, n , M. Koci n
Ed(s): C. Elkins
MeSH headings : Animals; Cecum / microbiology; Cecum / physiology; Chickens; Genomic Islands; Liver / microbiology; Liver / physiology; Poultry Diseases / genetics; Poultry Diseases / metabolism; Poultry Diseases / microbiology; Salmonella Infections, Animal / genetics; Salmonella Infections, Animal / metabolism; Salmonella Infections, Animal / microbiology; Salmonella enteritidis / genetics; Salmonella enteritidis / physiology; Salmonella typhimurium / genetics; Salmonella typhimurium / physiology; Spleen / microbiology; Spleen / physiology; Temperature
TL;DR:
In vivo experiments using chicks demonstrated that numbers of viable S. Typhimurium or S. Enteritidis bacteria within the liver and spleen organ sites were ≥4 orders of magnitude lower than those within the ceca, indicating poor survival within these tissues or a reduced capacity to traverse the host epithelial layer and reach liver/spleen sites or both.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID, Crossref
Added: August 6, 2018
2014 report
A vector for vaccination against Lyme Disease and other insect transmitted diseases using a live Salmonella vaccine
[Invention Disclosure].
Source: NC State University Libraries
Added: March 12, 2022
2014 conference paper
Comparative analysis of 16S amplicon sequencing data from Roche 454 and Ion Torrent PGM platforms
Allali, I., Cadenas, M. B., Ballou, A., Mendoza, M., Ali, R., Hassan, H., … Azcarate-Peril, M. A. (2014, May 20). Presented at the UNC Research Computing Symposium.
Event: UNC Research Computing Symposium on May 20, 2014
Source: NC State University Libraries
Added: March 12, 2022
2014 conference paper
Development of the chick microbiome: How early exposure influences future microbial diversity
Presented at the Symposium on Gut Health, St Louis, MO.
Event: Symposium on Gut Health at St Louis, MO
Source: NC State University Libraries
Added: March 12, 2022
2014 journal article
Ferric Uptake Regulator-Dependent Antinitrosative Defenses in Salmonella enterica Serovar Typhimurium Pathogenesis
INFECTION AND IMMUNITY, 82(1), 333–340.
MeSH headings : Analysis of Variance; Animals; Bacterial Proteins / immunology; Bacterial Proteins / physiology; Disease Models, Animal; Mice; Nitric Oxide Synthase Type II; Oxidative Stress / physiology; Repressor Proteins / deficiency; Repressor Proteins / immunology; Repressor Proteins / physiology; Salmonella Infections / microbiology; Salmonella Infections / physiopathology; Salmonella typhimurium / immunology; Salmonella typhimurium / pathogenicity; Stress, Physiological / physiology
TL;DR:
Investigations indicate that, in addition to playing a critical role in iron homeostasis, Fur is an important antinitrosative determinant of Salmonella pathogenesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
Pyruvate Protects Pathogenic Spirochetes from H2O2 Killing
PLoS ONE, 9(1), e84625.
Ed(s): R. Wooten
MeSH headings : Acetates / metabolism; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Borrelia burgdorferi / drug effects; Borrelia burgdorferi / genetics; Borrelia burgdorferi / metabolism; DNA Repair / drug effects; Gene Deletion; Glucose Oxidase / metabolism; Humans; Hydrogen Peroxide / toxicity; MutS DNA Mismatch-Binding Protein / genetics; MutS DNA Mismatch-Binding Protein / metabolism; Neutrophils / metabolism; Neutrophils / microbiology; Oxidative Stress / drug effects; Pyruvic Acid / metabolism; Pyruvic Acid / pharmacology; Reactive Oxygen Species / metabolism; Spirochaetales / drug effects; Spirochaetales / genetics; Spirochaetales / metabolism
TL;DR:
It is demonstrated that pyruvate, in addition to its classical role in central carbon metabolism, serves as an important H2O2 scavenger for pathogenic spirochetes and reduced ROS generated by human neutrophils in response to the Toll-like receptor 2 (TLR2) agonist zymosan.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018
2014 conference paper
The Chicken Gut Microbiome and Salmonella
Hassan, H. M. (2014, October 21). Invited presentation presented at the United State Animal Health Association – Annual Meeting, Arkansas, MO.
Event: United State Animal Health Association – Annual Meeting at Arkansas, MO on October 21, 2014
Source: NC State University Libraries
Added: March 12, 2022
2013 report
Attenuated FNR deficient enterobacteria
(Patent No. US8435506B2).
Source: NC State University Libraries
Added: March 12, 2022
2013 review
Transcriptional regulation by Ferric Uptake Regulator (Fur) in pathogenic bacteria
[Review of ]. FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 3.
author keywords: Ferric Uptake Regulator; iron; oxidative stress; gene regulation; pathogenic bacteria
MeSH headings : Animals; Bacteria / genetics; Bacteria / isolation & purification; Bacteria / metabolism; Bacterial Infections / microbiology; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Ferric Compounds / metabolism; Gene Expression Regulation, Bacterial; Host-Pathogen Interactions; Humans; Oxidative Stress; Reactive Oxygen Species / metabolism; Reactive Oxygen Species / toxicity; Repressor Proteins / genetics; Repressor Proteins / metabolism; Transcription, Genetic
TL;DR:
This review focuses on the breadth of Fur regulation in pathogenic bacteria since mutants of fur, perR, or zur exhibit reduced virulence within numerous animal and plant models of infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2012 report
Attenuated FNR Deficient Enterobacteria
(US Patent No. 8,101,168).
Source: NC State University Libraries
Added: March 12, 2022
2012 journal article
Direct fed microbial supplementation repartitions host energy to the immune system
JOURNAL OF ANIMAL SCIENCE, 90(8), 2639–2651.
Contributors: R. Qiu n, J. Croom n, R. Ali n, A. Ballou n, C. Smith n, C. Ashwell n , n , C. Chiang, M. Koci n
author keywords: broiler; direct fed microbials; energy metabolism; gene expression; probiotics; systemic immune function
MeSH headings : Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Chickens / immunology; Chickens / metabolism; Diet / veterinary; Dietary Supplements; Energy Metabolism / immunology; Enzyme-Linked Immunosorbent Assay; Erythrocytes / immunology; Gene Expression Regulation / immunology; Gram-Positive Bacteria / physiology; Immunoglobulin A / blood; Immunoglobulin G / blood; Male; Oxygen Consumption; Sheep; Time Factors
TL;DR:
Data indicate that supplementation with the direct fed microbial used in this study resulted in energy re-partitioning to the immune system and an increase in antibody production independent of changes in whole body metabolism or growth performance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2011 journal article
Analysis of the ArcA regulon in anaerobically grown Salmonella enterica sv. Typhimurium
BMC MICROBIOLOGY, 11.
MeSH headings : Anaerobiosis; Animals; Female; Gene Deletion; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Metabolic Networks and Pathways / genetics; Mice; Mice, Inbred C57BL; Microarray Analysis; Regulon; Repressor Proteins / genetics; Repressor Proteins / metabolism; Salmonella typhimurium / genetics; Salmonella typhimurium / growth & development; Salmonella typhimurium / metabolism
TL;DR:
The results demonstrated that in S. Typhimurium, ArcA serves as a transcriptional regulator coordinating cellular metabolism, flagella biosynthesis, and motility, and a set of 120 genes whose regulation was shared with the anaerobic redox regulator, Fnr.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
Fur Negatively Regulates hns and Is Required for the Expression of HilA and Virulence in Salmonella enterica Serovar Typhimurium
JOURNAL OF BACTERIOLOGY, 193(2), 497–505.
MeSH headings : Animals; Bacterial Proteins / biosynthesis; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Chromatin Immunoprecipitation; DNA, Bacterial / metabolism; DNA-Binding Proteins / biosynthesis; DNA-Binding Proteins / metabolism; Disease Models, Animal; Gene Expression Regulation, Bacterial; Gene Knockout Techniques; Genes, Bacterial; Genomic Islands; Mice; Mice, Inbred C3H; Operon; Protein Binding; Repressor Proteins / genetics; Repressor Proteins / metabolism; Salmonella Infections, Animal / microbiology; Salmonella typhimurium / pathogenicity; Salmonella typhimurium / physiology; Survival Analysis; Trans-Activators / biosynthesis; Transcription Factors / biosynthesis; Virulence; Virulence Factors / biosynthesis
TL;DR:
Fur is required for virulence in Salmonella enterica serovar Typhimurium and that Fur is necessary for the activation of hilA, as well as of other HilA-dependent genes, invF and sipC, and chromatin immunoprecipitation was used to show that Fur bound to the upstream region of hns in a metal-dependent fashion.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2011 journal article
The Fur regulon in anaerobically grown Salmonella enterica sv. Typhimurium: identification of new Fur targets
BMC MICROBIOLOGY, 11.
MeSH headings : Anaerobiosis; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Gene Expression Regulation, Bacterial; Iron / metabolism; Oxygen / metabolism; Regulon; Repressor Proteins / genetics; Repressor Proteins / metabolism; Salmonella typhimurium / genetics; Salmonella typhimurium / metabolism
TL;DR:
This work identified twenty-six new targets of Fur regulation, and demonstrates that H-NS repressed genes are down-regulated in Δfur, indicating that Fur is a positive factor in ftnB regulation, while serving to repress the expression of hmpA.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2010 article
Evolution of the Probiotic Concept: From Conception to Validation and Acceptance in Medical Science
ADVANCES IN APPLIED MICROBIOLOGY, VOL 72, Vol. 72, pp. 1–41.
MeSH headings : Animals; Bifidobacterium; Gastrointestinal Tract / microbiology; Humans; Immunologic Factors / pharmacology; Lactobacillus; Organisms, Genetically Modified / microbiology; Probiotics / pharmacology; Probiotics / therapeutic use
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2010 journal article
Role of Antioxidant Enzymes in Bacterial Resistance to Organic Acids
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 76(9), 2747–2753.
Contributors: J. Bruno-Bárcena n , M. Andrea Azcárate-Peril* & *
MeSH headings : Antioxidants / metabolism; Antioxidants / physiology; Bacterial Proteins / genetics; Escherichia coli / genetics; Escherichia coli / metabolism; Hydrogen-Ion Concentration; Iron / metabolism; Lactic Acid / toxicity; Oxidative Stress; Streptococcus thermophilus / drug effects; Streptococcus thermophilus / enzymology; Stress, Physiological; Superoxide Dismutase / genetics; Superoxide Dismutase / metabolism; Superoxide Dismutase / physiology
TL;DR:
It is suggested that acid stress triggers an iron-mediated oxidative stress that can be ameliorated by MnSOD and iron chelators and may explain the ability of some microorganisms to survive better in acidified environments, as in acid foods during fermentation and accumulation of lactic acid or during passage through the low pH of the stomach.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2008 journal article
Antimicrobial properties of milkfat globule membrane fractions
JOURNAL OF FOOD PROTECTION, 71(1), 126–133.
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacillus cereus / growth & development; Cattle; Consumer Product Safety; Culture Media / chemistry; Escherichia coli O157 / growth & development; Food Contamination / prevention & control; Food Microbiology; Food Preservation / methods; Food Preservatives / pharmacology; Hydrogen Peroxide / pharmacology; Lactobacillus / growth & development; Membrane Proteins / pharmacology; Microbial Sensitivity Tests; Milk / chemistry; Protein Hydrolysates / pharmacology; Pseudomonas fluorescens / growth & development; Salmonella typhimurium / growth & development
TL;DR:
It is determined that the antimicrobial effects observed on BHI plates were due to the generation of H2O2 by xanthine oxidase, a major protein constituent of the MFGMs, as a result of purine catalysis, and this substrate is present in BHI but lacking in LB medium.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2008 journal article
Effects of pH, Dissolved Oxygen, and Ionic Strength on the Survival of Escherichia coli O157:H7 in Organic Acid Solutions
JOURNAL OF FOOD PROTECTION, 71(12), 2404–2409.
MeSH headings : Acids / pharmacology; Colony Count, Microbial; Consumer Product Safety; Cucumis sativus / microbiology; Dose-Response Relationship, Drug; Escherichia coli O157 / drug effects; Escherichia coli O157 / growth & development; Food Contamination / analysis; Food Preservation / methods; Humans; Hydrogen-Ion Concentration; Osmolar Concentration; Oxygen / pharmacology
TL;DR:
The results demonstrate that E. coli O157:H7 may survive better than previously expected from studies with acid solutions containing dissolved oxygen, and many acid and acidified foods are sold in hermetically sealed containers with oxygen-limiting conditions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2007 journal article
Anti-inflammatory properties of Lactobacillus gasseri expressing manganese superoxide dismutase using the interleukin 10-deficient mouse model of colitis
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 293(4), G729–G738.
Contributors: I. Carroll *, J. Andrus*, J. Bruno-Bárcena n , T. Klaenhammer n, n & D. Threadgill
author keywords: probiotic; Lactobacilli; oxidative stress; inflammatory bowel disease
MeSH headings : Animals; Anti-Inflammatory Agents / therapeutic use; Colitis / drug therapy; Colitis / pathology; Colon / pathology; Cyclooxygenase 2 / metabolism; Disease Models, Animal; Immunohistochemistry; Interleukin-10 / deficiency; Lactobacillus / enzymology; Mice; Peroxidase / metabolism; Probiotics / therapeutic use; Specific Pathogen-Free Organisms; Superoxide Dismutase / biosynthesis; Superoxide Dismutase / therapeutic use
TL;DR:
This study demonstrates that L. gasseri producing MnSOD has significant anti-inflammatory activity that reduces the severity of colitis in the IL-10-deficient mouse.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2007 journal article
FNR is a global regulator of virulence and anaerobic metabolism in Salmonella enterica serovar typhimurium (ATCC 14028s)
JOURNAL OF BACTERIOLOGY, 189(6), 2262–2273.
MeSH headings : Anaerobiosis; Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Cells, Cultured; DNA-Binding Proteins / genetics; DNA-Binding Proteins / metabolism; Escherichia coli Proteins / genetics; Gene Expression Profiling; Gene Expression Regulation, Bacterial; Humans; Iron-Sulfur Proteins / genetics; Iron-Sulfur Proteins / metabolism; Macrophages, Peritoneal / microbiology; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Mutation; Oligonucleotide Array Sequence Analysis; Salmonella Infections / microbiology; Salmonella Infections / pathology; Salmonella typhimurium / genetics; Salmonella typhimurium / growth & development; Salmonella typhimurium / metabolism; Salmonella typhimurium / pathogenicity; Transcription Factors / genetics; Transcription Factors / metabolism; Virulence
TL;DR:
The role of FNR as a positive regulator of motility, flagellar biosynthesis, and pathogenesis was confirmed by showing that the isogenic fnr mutant is nonmotile, lacks flagella, is attenuated in mice, and does not survive inside macrophages.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2006 journal article
Transcriptional and functional analysis of oxalyl-coenzyme A (CoA) decarboxylase and formyl-CoA transferase genes from Lactobacillus acidophilus
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 72(3), 1891–1899.
Contributors: M. Azcarate-Peril n, J. Bruno-Bárcena* , * & T. Klaenhammer n
MeSH headings : Carboxy-Lyases / genetics; Carboxy-Lyases / metabolism; Coenzyme A-Transferases / genetics; Coenzyme A-Transferases / metabolism; Gene Expression Regulation, Bacterial; Lactobacillus acidophilus / enzymology; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / growth & development; Oligonucleotide Array Sequence Analysis; Operon; Oxalates / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic
TL;DR:
Transcriptional analysis using cDNA microarrays and reverse transcription-quantitative PCR revealed that mildly acidic conditions were a prerequisite for frc and oxc transcription, andOxalate-dependent induction of these genes occurred only in cells first adapted to subinhibitory concentrations of oxalate and then exposed to pH 5.5.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2005 journal article
Marker-free chromosomal integration of the manganese superoxide dismutase gene (sodA) from Streptococcus thermophilus into Lactobacillus gasseri
FEMS MICROBIOLOGY LETTERS, 246(1), 91–101.
Contributors: J. Bruno-Bárcena n , M. Azcárate-Peril n, T. Klaenhammer n & n
author keywords: functional gene replacement; manganese superoxide dismutase; oxidative stress; Lactobacillus gasseri; lactic acid bacteria; probiotics
MeSH headings : Anti-Bacterial Agents / pharmacology; Bacterial Proteins / analysis; Chromosomes, Bacterial / genetics; Gene Expression; Hydrogen Peroxide / pharmacology; Lactobacillus / enzymology; Lactobacillus / genetics; Lactobacillus / growth & development; Plasmids / genetics; RNA, Bacterial / analysis; RNA, Messenger / analysis; Streptococcus thermophilus / enzymology; Streptococcus thermophilus / genetics; Superoxide Dismutase / genetics; Transformation, Bacterial
TL;DR:
This is the first report showing the successful utilization of the pORI plasmids system to generate marker-free gene integration in L. gasseri strains.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2004 journal article
Expression of a heterologous manganese superoxide dismutase gene in intestinal lactobacilli provides protection against hydrogen peroxide toxicity
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 70(8), 4702–4710.
Contributors: J. Bruno-Bárcena* , J. Andrus*, S. Libby*, T. Klaenhammer n & n
MeSH headings : Cloning, Molecular; Humans; Hydrogen Peroxide / pharmacology; Intestines / microbiology; Lactobacillus / classification; Lactobacillus / drug effects; Lactobacillus / enzymology; Lactobacillus / genetics; Oxidative Stress / drug effects; Protein Biosynthesis; Streptococcus / enzymology; Streptococcus / genetics; Superoxide Dismutase / genetics; Superoxide Dismutase / metabolism; Transcription, Genetic
TL;DR:
The data show that MnSOD protects cells against hydrogen peroxide by removing O2·− and preventing the redox cycling of iron and is the first report of a sodA from S. thermophilus being expressed in other lactic acid bacteria.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
2004 journal article
Role of catalase and oxyR in the viable but nonculturable state of Vibrio vulnificus
FEMS MICROBIOLOGY ECOLOGY, 50(3), 133–142.
author keywords: VBNC; oxidative stress; catalase; H2O2; nonculturability
MeSH headings : Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Catalase / metabolism; Cold Temperature; Colony Count, Microbial; DNA, Bacterial / chemistry; DNA, Bacterial / genetics; Gene Deletion; Hydrogen Peroxide / toxicity; Microbial Viability; Molecular Sequence Data; Sequence Analysis, DNA; Trans-Activators / genetics; Trans-Activators / metabolism; Vibrio vulnificus / drug effects; Vibrio vulnificus / genetics; Vibrio vulnificus / growth & development; Vibrio vulnificus / physiology
TL;DR:
This is the first study providing direct evidence for the metabolic basis of nonculturability and the viable but nonculturable state and an oxyR mutant which lacks catalase activity is generated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2003 journal article
Effect of malic acid on the growth kinetics of Lactobacillus plantarum
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 63(2), 207–211.
MeSH headings : Cucumis sativus / metabolism; Cucumis sativus / microbiology; Culture Media; Fermentation; Kinetics; Lactobacillus / drug effects; Lactobacillus / growth & development; Malates / pharmacology
TL;DR:
The results clearly demonstrate the energy-sparing effect of malic acid on the growth- and non-growth-associated energy requirements for L. plantarum.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
13. Climate Action
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2003 journal article
Molecular characterization and functional analysis of the manganese-containing superoxide dismutase gene (sodA) from Streptococcus thermophilus AO54
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 420(1), 103–113.
author keywords: Streptococcus thermophilus; superoxide dismutase; MnSOD; sodA sequence; sodA mutant; SOD-null mutant; oxygen sensitivity; manganese ions; DNA polymerase III
MeSH headings : Amino Acid Sequence; Gene Expression Regulation, Enzymologic / drug effects; Magnesium Chloride / pharmacology; Molecular Sequence Data; Mutagenesis, Site-Directed; Sequence Alignment; Sequence Analysis, Protein; Species Specificity; Streptococcus / chemistry; Streptococcus / drug effects; Streptococcus / enzymology; Streptococcus / genetics; Structure-Activity Relationship; Superoxide Dismutase / chemistry; Superoxide Dismutase / genetics; Superoxide Dismutase / metabolism
TL;DR:
The results suggest that sodA is essential for the aerobic growth of S. thermophilus and in the absence of functional SodA, manganese ions may provide partial protection against oxygen toxicity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2003 journal article
RpoS-dependent stress response and exoenzyme production in Vibrio vulnificus
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 69(10), 6114–6120.
MeSH headings : Culture Media; Enzymes / biosynthesis; Heat-Shock Response; Humans; Hydrogen Peroxide / pharmacology; Hydrogen-Ion Concentration; Molecular Sequence Data; Movement; Mutation; Osmolar Concentration; Vibrio vulnificus / enzymology; Vibrio vulnificus / genetics; Vibrio vulnificus / growth & development; Vibrio vulnificus / physiology
TL;DR:
These studies suggest that rpoS in V. vulnificus is important for adaptation to environmental changes and may have a role in virulence.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
Azotobacter chroococcum does not contain sodA or its gene product Mn-superoxide dismutase
Canadian Journal of Microbiology, 48(2), 183–187.
author keywords: FeSOD; Cu-ZnSOD; MnSOD; Azotobacter chroococcum; Azotobacter vinelandii
MeSH headings : Amino Acid Sequence; Azotobacter / enzymology; Azotobacter / genetics; Molecular Sequence Data; Polymerase Chain Reaction; Sequence Homology, Amino Acid; Superoxide Dismutase / analysis; Superoxide Dismutase / genetics
TL;DR:
Results dispute the assertion that A. chroococcum contains Mn-superoxide dismutase and refute the assertion by Buchanan and Lees (Can. J. Microbiol. 26: 441-447, 1980).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2001 journal article
Characterization of the iron superoxide dismutase gene of <i>Azotobacter vinelandii</i>: <i>sodB</i> may be essential for viability
Canadian Journal of Microbiology, 47(1), 63–71.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 6, 2018
2001 speech
Oxygen Radical Toxicity
Hassan, H. (2001, May). Presented at the Annual Meeting of the Genotoxicity and Environmental Mutagen Society (GEMS), Research Triangle Park, NC.
Event: Annual Meeting of the Genotoxicity and Environmental Mutagen Society (GEMS) at Research Triangle Park, NC on May 16, 2001
Source: NC State University Libraries
Added: March 12, 2022
1998 journal article
Mechanism of regulation of 8-hydroxyguanine endonuclease by oxidative stress: Roles of fnr, arcA, and fur
FREE RADICAL BIOLOGY AND MEDICINE, 24(7-8), 1193–1201.
author keywords: oh(8)Gua endonuclease; regulation; DNA repair; regulon genes; MutM; FPG; free radical
MeSH headings : Bacterial Outer Membrane Proteins / genetics; Bacterial Proteins / genetics; Base Sequence; Catalase / biosynthesis; Chelating Agents / pharmacology; DNA, Bacterial / genetics; DNA, Bacterial / metabolism; DNA-Formamidopyrimidine Glycosylase; Enzyme Induction / drug effects; Escherichia coli / drug effects; Escherichia coli / enzymology; Escherichia coli / genetics; Escherichia coli Proteins; Free Radicals / metabolism; Genes, Bacterial; Glucosephosphate Dehydrogenase / biosynthesis; Hydrogen Peroxide / toxicity; Iron-Sulfur Proteins / genetics; Molecular Sequence Data; Mutation; N-Glycosyl Hydrolases / biosynthesis; Oxidative Stress / drug effects; Paraquat / toxicity; Repressor Proteins / genetics; Superoxide Dismutase / biosynthesis; Superoxide Dismutase / metabolism
TL;DR:
Findings suggest that the oxidative regulation of oh8Gua endonuclease is under control of fnr, fur, and arcA, where fnr plays a predominant role, and will enhance the efficiency of cellular growth and survival in the aerobic environment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
1997 journal article
Characterization of superoxide dismutase in Streptococcus thermophilus
Applied and Environmental Microbiology, 63(9), 3732–3735.
Source: NC State University Libraries
Added: August 6, 2018
1997 chapter
Cytotoxicity of oxyradicals and the evolution of superoxide dismutases
In D. Massaro & L. Clerch (Eds.), Oxygen, gene expression and cellular function (pp. 26–51). New York: Marcel Dekker.
Ed(s): D. Massaro & L. Clerch
Source: NC State University Libraries
Added: March 12, 2022
1996 journal article
Enhancement of the antibacterial activity of ampicillin by liposome encapsulation
Drug Delivery, 3(4), 273–278.
TL;DR:
It was showed that encapsulation of ampicillin in liposomes prepared with synthetic lecithins enhanced its antibiotic activity against both Amp-sensitive and Amp-resistant Escherichia coli.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1995 journal article
Binding of integration host factor (IHF) to the Escherichia coli sodA gene and its role in the regulation of a sodA-lacZ fusion gene
Molecular and General Genetics MGG, 246(2), 228–235.
author keywords: ESCHERICHIA COLI; SUPEROXIDE DISMUTASE (SOD); INTEGRATION HOST FACTOR (IHF); MOBILITY-SHIFT
MeSH headings : 2,2'-Dipyridyl / pharmacology; Aerobiosis; Anaerobiosis; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Base Sequence; DNA, Bacterial / metabolism; DNA-Binding Proteins / metabolism; Escherichia coli / genetics; Gene Expression Regulation, Bacterial; Integration Host Factors; Lac Operon; Molecular Sequence Data; Promoter Regions, Genetic; Protein Binding; Recombinant Fusion Proteins / biosynthesis; Superoxide Dismutase / biosynthesis; Superoxide Dismutase / genetics
TL;DR:
The clectrophoretic mobility-shift assay was used to reveal specific DNA-protein interactions between DNA fragments containing the sodA promoter and proteins present in Escherichia coli cell-free extracts, and evidence presented suggests that IHF binds to multiple sites in the SodA promoter.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1995 speech
Metals in Biology
Presented at the Keystone Symposium, Park City, UT.
Event: Keystone Symposium at Park City, UT on March 20-24, 1995
Source: NC State University Libraries
Added: March 12, 2022
1994 chapter
Regulation of the biosynthesis of manganese-superoxide dismutase in Escherichia coli in response to iron and manganese
In K. Asada & T. Yoshikawa (Eds.), Frontiers of reactive oxygen species in biology and medicine (pp. 245–250). NY: Elsevier Science.
Ed(s): K. Asada & T. Yoshikawa
Source: NC State University Libraries
Added: March 12, 2022
1994 journal article
Roles of manganese and iron in the regulation of the biosynthesis of manganese-superoxide dismutase inEscherichia coli
FEMS Microbiology Reviews, 14(4), 315–323.
MeSH headings : Amino Acid Sequence; Bacterial Proteins / physiology; Base Sequence; Escherichia coli / enzymology; Escherichia coli Proteins; Iron / pharmacology; Iron-Sulfur Proteins; Manganese / pharmacology; Molecular Sequence Data; Repressor Proteins / physiology; Superoxide Dismutase / biosynthesis
TL;DR:
A model for the regulation of the MnSOD has been proposed in which the Mn SOD gene (sodA) is negatively regulated at the level of transcription by an iron-containing redox-sensitive repressor protein.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1994 journal article
Stability of Escherichia coli sodA mRNA and identification of the transcriptional start site(s) under different environmental and oxidative stresses
Free Radical Biology and Medicine, 17(3), 209–213.
author keywords: MN-SUPEROXIDE DISMUTASE; SODA MESSENGER-RNA STABILITY; TRANSCRIPTION START SITE; NALIDIXIC ACID; PARAQUAT; 2,2'-DIPYRIDYL; TRANSCRIPTION; TRANSLATION; FREE RADICALS
MeSH headings : 2,2'-Dipyridyl / pharmacology; Base Sequence; Drug Stability; Escherichia coli / genetics; Half-Life; Manganese; Molecular Sequence Data; Nalidixic Acid / pharmacology; Oxidation-Reduction; Oxidative Stress; Paraquat / pharmacology; Promoter Regions, Genetic; RNA, Messenger / metabolism; Reactive Oxygen Species / pharmacology; Superoxide Dismutase / genetics; Transcription, Genetic / drug effects
TL;DR:
Results indicate that under oxidative stress/inducing conditions, the increase in aerobic transcription of sodA occurs from only one transcription start site without affecting the stability of SodA mRNA, and suggests that no translational regulation occurs aerobically.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1994 journal article
The Effects of fur on the Transcriptional and Post-transcriptional Regulation of MnSOD Gene (sodA) in Escherichia coli
Archives of Biochemistry and Biophysics, 309(2), 288–292.
MeSH headings : Aerobiosis; Bacterial Proteins / pharmacology; Escherichia coli / enzymology; Escherichia coli / genetics; Gene Expression Regulation, Bacterial / drug effects; Iron / metabolism; Manganese; Mutation; Plasmids; RNA, Messenger / metabolism; Recombinant Fusion Proteins / metabolism; Repressor Proteins / pharmacology; Superoxide Dismutase / genetics; Superoxide Dismutase / metabolism; Transcription, Genetic / drug effects; beta-Galactosidase / genetics
TL;DR:
Fur plays the role of a repressor at the transcriptional level, but it also plays an indirect role at the post-transcriptional level where it affects the maturation of SodA into a fully active enzyme, Mn2SodA (MnSOD).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1993 journal article
Characterization of cis-Acting Regulatory Mutations Causing Anaerobic Expression of the sodA Gene in Escherichia coli
Archives of Biochemistry and Biophysics, 302(2), 372–379.
MeSH headings : Alleles; Anaerobiosis; Base Sequence; DNA Transposable Elements / genetics; DNA, Recombinant / genetics; Escherichia coli / genetics; Gene Expression Regulation, Bacterial / drug effects; Genes, Bacterial / genetics; Molecular Sequence Data; Mutagenesis, Insertional / genetics; Paraquat / pharmacology; Plasmids / genetics; Promoter Regions, Genetic / genetics; Recombinant Proteins / biosynthesis; Regulatory Sequences, Nucleic Acid / genetics; Sequence Homology, Nucleic Acid; Superoxide Dismutase / biosynthesis; Superoxide Dismutase / genetics; beta-Galactosidase / biosynthesis; beta-Galactosidase / genetics
TL;DR:
To further investigate the mode of regulation of the gene (sodA) encoding this enzyme, cis-acting regulatory mutations in a strain containing a sodA::lacZ gene fusion were studied and revealed an IS2 insertion element in the promoter region of one of the mutants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1993 journal article
Characterization of regulatory mutations causing anaerobic derepression of the sodA gene in Escherichia coli K12: cooperation between cis- and trans-acting regulatory loci
Journal of General Microbiology, 139(11), 2677–2684.
MeSH headings : Base Sequence; Escherichia coli / enzymology; Escherichia coli / genetics; Gene Expression Regulation, Bacterial / physiology; Gene Expression Regulation, Enzymologic / physiology; Genes, Bacterial / physiology; Genes, Regulator / physiology; Iron Chelating Agents / metabolism; Lac Operon; Molecular Sequence Data; Mutation / physiology; Regulatory Sequences, Nucleic Acid / physiology; Superoxide Dismutase / genetics; Transcriptional Activation / physiology
TL;DR:
The data presented suggest that the cis-mutation in UV14 (sodA14) affects the Fur-binding site in the sodA promoter, while having no effect on Fnr or Arc mediated repression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1993 journal article
Cloning and expression of the manganese superoxide dismutase gene of Escherichia coli in Lactococcus lactis and Lactobacillus gasseri
Molecular and General Genetics MGG, 239(1-2), 33–40.
author keywords: ESCHERICHIA-COLI; SUPEROXIDE DISMUTASE; FUSION PROTEIN; LACTOCOCCUS; LACTOBACILLUS
MeSH headings : Base Sequence; Blotting, Western; Cloning, Molecular; DNA, Bacterial; Electrophoresis, Polyacrylamide Gel; Escherichia coli / enzymology; Escherichia coli / genetics; Escherichia coli / growth & development; Gene Expression Regulation, Enzymologic / drug effects; Lactobacillus / genetics; Lactococcus lactis / genetics; Manganese / pharmacology; Molecular Sequence Data; Oxygen / metabolism; Paraquat / pharmacology; Plasmids; Superoxide Dismutase / genetics
TL;DR:
The Escherichia coli sodA gene encoding the antioxidant enzyme Mn-containing superoxide dismutase (MnSOD), was cloned in the expression vector pMG36e, which has a multiple cloning site down-stream of a promoter and Shine-Dalgarno sequences derived from Lactococcus.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1993 journal article
Modeling the cucumber fermentation: Growth ofLactobacillus plantarum
Journal of Industrial Microbiology, 12(3-5), 341–345.
author keywords: LACTIC ACID BACTERIA; LACTIC ACID; ACETIC ACID; SODIUM CHLORIDE; PH; HYDROGEN ION
TL;DR:
The present paper summarizes experimental data and the development of a model for growth of the commercially important bacterium, lactobacillus plantarum, in cucumber juice, which provides an excellent correlation of data for the influence on bacterial growth rate of NaCl, protons (H+), and the neutral, inhibitory forms of acetic acid and the fermentation product, lactic acid.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(Web of Science)
12. Responsible Consumption and Production
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1993 journal article
Modeling the specific growth rate of Lactobacillus plantarum in cucumber extract
Applied Microbiology and Biotechnology, 40(1).
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1993 journal article
Transcriptional activation of Mn-superoxide dismutase gene (sodA) of Escherichia coli by MnCl2
Biochimica Et Biophysica Acta (BBA) - Gene Structure and Expression, 1216(2), 186–190.
author keywords: SUPEROXIDE DISMUTASE; MANGANESE ENZYME; TRANSCRIPTION ACTIVATION; TOPOLOGY; IRON-CONTAINING REPRESSOR PROTEIN; (ESCHERICHIA-COLI)
MeSH headings : Chlorides / pharmacology; Escherichia coli / drug effects; Escherichia coli / enzymology; Escherichia coli / genetics; Gene Expression; Iron / analysis; Manganese / analysis; Manganese Compounds / pharmacology; Mutation; Superoxide Dismutase / genetics; Transcription, Genetic / drug effects; beta-Galactosidase / genetics
TL;DR:
Results show that Mn2+ causes activation of sodA transcription, and it is found that manganese was capable of altering DNA topology.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1992 journal article
Characterization oftrans-acting regulatory elements affecting the expression of Mn-superoxide dismutase (sodA) inEscherichia coli
Current Microbiology, 25(3), 135–141.
TL;DR:
Complementation studies revealed that eitherarc (aerobic respiratory control) orfur (ferric uptake regulation) loci independently complemented anaerobic expression of asodA::lacZ protein fusion in one mutant strain (UV16), which exhibited phenotypes typical offur andarc mutants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1992 journal article
Isolation and characterization of an Escherichia coli mutant elevated in manganese-containing superoxide dismutase biosynthesis
Biochem. (Life Sci. Adv.), 11, 23–30.
Source: NC State University Libraries
Added: March 12, 2022
1992 journal article
Regulatory roles of Fnr, Fur, and Arc in expression of manganese-containing superoxide dismutase in Escherichia coli.
Proceedings of the National Academy of Sciences, 89(8), 3217–3221.
MeSH headings : 2,2'-Dipyridyl / pharmacology; Aerobiosis; Anaerobiosis; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Base Sequence; Escherichia coli / drug effects; Escherichia coli / enzymology; Escherichia coli / genetics; Escherichia coli Proteins; Gene Expression Regulation, Bacterial; Gene Expression Regulation, Enzymologic; Genes, Bacterial; Genotype; Iron-Sulfur Proteins; Isoenzymes / biosynthesis; Isoenzymes / genetics; Manganese / metabolism; Molecular Sequence Data; Nitrates / pharmacology; Oligodeoxyribonucleotides; Oxidants / pharmacology; Paraquat / pharmacology; Recombinant Fusion Proteins / biosynthesis; Recombinant Proteins / biosynthesis; Repressor Proteins / genetics; Repressor Proteins / metabolism; Superoxide Dismutase / biosynthesis; Superoxide Dismutase / genetics; Transcription Factors / genetics; Transcription Factors / metabolism; Viral Proteins / genetics; Viral Proteins / metabolism; Viral Regulatory and Accessory Proteins; beta-Galactosidase / biosynthesis; beta-Galactosidase / genetics
TL;DR:
It is concluded that Fnr, Arc, and Fur act as anaerobic repressors of sodA and the regulation of SodA by Fur (ferric uptake regulation protein), Arc (aerobic respiratory control), and Fnr is independent of the superoxide response regulon SoxRS.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1992 journal article
Transcriptional regulation of Mn-superoxide dismutase gene (sodA) of Escherichia coli is stimulated by DNA gyrase inhibitors
Archives of Biochemistry and Biophysics, 299(1), 185–192.
MeSH headings : 2,2'-Dipyridyl / pharmacology; Aminocoumarins; Anti-Bacterial Agents / pharmacology; Cloning, Molecular; Coumarins / pharmacology; Escherichia coli / drug effects; Escherichia coli / enzymology; Escherichia coli / genetics; Gene Expression Regulation, Enzymologic / drug effects; Kinetics; Paraquat / pharmacology; Recombinant Fusion Proteins / metabolism; Sodium Iodide / pharmacology; Superoxide Dismutase / genetics; Superoxide Dismutase / metabolism; Topoisomerase II Inhibitors; Transcription, Genetic / drug effects; beta-Galactosidase / genetics; beta-Galactosidase / metabolism
TL;DR:
The results indicate that the effect of DNA gyrase inhibitors is secondary to the cis- and trans-regulatory elements of SodA and suggest that changes in DNA topology may affect transcriptional regulation of sodA.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1991 chapter
The role of oxygen free radicals in biology and evolution
In C. Bryant (Ed.), Metazoan Life Without Oxygen (pp. 19–37). NY: Chapman and Hall.
Ed(s): C. Bryant
Source: NC State University Libraries
Added: March 12, 2022
1991 journal article
Use of continuous culture for internal pH determination of lactic acid bacteria
Food Microbiology, 8(2), 137–142.
TL;DR:
Oxygen, manganese, cell density, external pH, and organic acid production were shown not to influence the internal pH of these bacteria when grown in continuous culture.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
1990 journal article
Acid Tolerance of Leuconostoc mesenteroides and Lactobacillus plantarum
Applied and Environmental Microbiology, 56(7), 2120–2124.
TL;DR:
The comparatively low growth-limiting internal pH and ability to maintain a pH gradient at high organic acid concentration may contribute to the ability of L. plantarum to terminate vegetable fermentations.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1990 chapter
Superoxide dismutases in aerobic organisms
In R. G. Alscher & J. R. Cumming (Eds.), Stress Responses in Plants: Adaptation and Acclimation Mechanisms (pp. 175–199). NY: Wiley-Liss.
Ed(s): R. Alscher & J. Cumming
Source: NC State University Libraries
Added: March 12, 2022
1990 journal article
Use of site-directed mutagenesis to identify an upstream regulatory sequence of sodA gene of Escherichia coli K-12.
Proceedings of the National Academy of Sciences, 87(7), 2618–2622.
MeSH headings : 2,2'-Dipyridyl / pharmacology; Aerobiosis; Base Sequence; Escherichia coli / drug effects; Escherichia coli / enzymology; Escherichia coli / genetics; Genes, Bacterial; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Paraquat / pharmacology; Plasmids; Regulatory Sequences, Nucleic Acid; Restriction Mapping; Superoxide Dismutase / biosynthesis; Superoxide Dismutase / genetics
TL;DR:
The results indicate that the region within and around the mutated sequence probably plays an important role in sodA regulation and that the mutation disrupts a sequence that interacts with the repressor.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1989 journal article
An electron spin resonance study of oxyradical generation in superoxide dismutase- and catalase-deficient mutants of Escherichia coli K-12
Archives of Biochemistry and Biophysics, 271(2), 323–331.
MeSH headings : Catalase / metabolism; Cyclic N-Oxides; Electron Spin Resonance Spectroscopy; Escherichia coli / drug effects; Escherichia coli / enzymology; Escherichia coli / genetics; Free Radicals; Hydroxides / metabolism; Hydroxyl Radical; Mutation; NAD / metabolism; NADP / metabolism; Oxygen / metabolism; Pyocyanine / pharmacology; Spin Labels; Superoxide Dismutase / metabolism; Superoxides / metabolism
TL;DR:
The response of superoxide dismutase- and catalase-deficient strains of Escherichia coli to redox active compounds was examined by electron spin resonance and levels of radicals formed in response to pyocyanine in situ were extremely low.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1989 chapter
Attenuation of Antioxidant Enzymes in Response to Oxidative Stresses1
In J. C. Somogyi & H. R. Müller (Eds.), Nutritional Impact of Food Processing. 25th Symposium of the Group of European Nutritionists, Reykjavik, September 1987 (pp. 278–287).
Ed(s): J. Somogyi & H. Müller
Event: 25th Symposium of the Group of European Nutritionists at Reykjavik, Iceland
MeSH headings : Antioxidants / pharmacology; Catalase; Oxidation-Reduction; Oxygen / toxicity; Peroxidases; Superoxide Dismutase
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1989 journal article
Effect of temperature andhtpRon the biosynthesis of superoxide dismutase inEscherichia coli
FEMS Microbiology Letters, 58(2-3), 133–137.
TL;DR:
The synthesis of Mn- and FeSODs in response to temperature changes was examined in strains of Escherichia coli with different mutations in sod and htpR genes, with results that showed FeS OD was more stable at 42 degrees C than was MnSOD.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1989 chapter
Microbial Superoxide Dismutases
In Advances in Genetics (pp. 65–97).
MeSH headings : Bacteria / enzymology; Bacteria / genetics; Biological Evolution; Cloning, Molecular; Gene Expression Regulation; Manganese / metabolism; Mutation; Plants / enzymology; Superoxide Dismutase / genetics; Superoxide Dismutase / metabolism; Superoxides / metabolism
TL;DR:
The evolution of three types of SODs to accomplish the same reaction in different organisms attests to their vital role in aerobic survival and the knowledge gained from E. coli will make it possible to explore the regulation of S ODs in other organisms.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1988 journal article
An assay for the detection of superoxide dismutase in individual Escherichia coli colonies
Analytical Biochemistry, 168(2), 455–461.
MeSH headings : Bacteriological Techniques; Escherichia coli / enzymology; Mutation; Superoxide Dismutase / analysis
TL;DR:
This assay provides a method for screening a population of cells for mutants deficient in or overproducing superoxide dismutase, and can detect the presence of superoxide Dismutase and the relative amount of enzyme as well.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1988 journal article
Antibacterial activity of plantaricin SIK-83, a bacteriocin produced by Lactobacillus plantarum
Biochimie, 70(3), 381–390.
MeSH headings : Adsorption; Bacteria / drug effects; Bacteriocins / biosynthesis; Bacteriocins / pharmacology; Bacteriolysis; Cell Membrane / drug effects; Cell Survival / drug effects; Lactobacillus / metabolism; Microbial Sensitivity Tests
TL;DR:
It was shown that the bacteriocin binds specifically to sensitive cells but not to nonsensitive lactic acid bacteria, the producer strain or Gram-negative bacteria, and could be rescued by treatment with proteolytic enzymes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1988 journal article
Induction of the manganese-containing superoxide dismutase in Escherichia coli is independent of the oxidative stress (oxyR-controlled) regulon.
Journal of Biological Chemistry, 263(29), 14808–14811.
TL;DR:
The data clearly demonstrate that the induction of manganese-superoxide dismutase is independent of the oxyR-controlled regulon.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1988 journal article
Isolation and characterization of respiratory-deficient mutants of Escherichia coli K-12
Journal of Bacteriology, 170(1), 78–83.
MeSH headings : Aerobiosis; Catalase / metabolism; Chromosome Mapping; Culture Media; Cytochromes / metabolism; Escherichia coli / enzymology; Escherichia coli / genetics; Escherichia coli / growth & development; Escherichia coli / metabolism; Fermentation; Genes, Bacterial; Glucose / metabolism; Heme / biosynthesis; Kinetics; Mutation; Oxygen Consumption; Peroxidases / metabolism; Superoxide Dismutase / metabolism
TL;DR:
Several mutants of Escherichia coli K-12 defective in aerobic metabolism were isolated and one such mutant was found to be deficient in cytochromes, heme, and catalase, which produced lactic acid as the principal fermentation product.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1988 journal article
Regulation and synthesis of superoxide dismutase
Free Radical Biology and Medicine, 5, 377–385.
Source: NC State University Libraries
Added: March 12, 2022
1988 journal article
Response of hydroperoxidase and superoxide dismutase deficient mutants of Escherichia coli K-12 to oxidative stress
Canadian Journal of Microbiology, 34(10), 1171–1176.
MeSH headings : Anaerobiosis; Antioxidants; Escherichia coli / enzymology; Escherichia coli / genetics; Escherichia coli / growth & development; Ethylmaleimide / toxicity; Iodoacetates / toxicity; Iodoacetic Acid; Mutation; Oxygen Consumption / drug effects; Peroxidase / deficiency; Peroxidase / genetics; Superoxide Dismutase / deficiency; Superoxide Dismutase / genetics
TL;DR:
Strips of E. coli deficient in superoxide dismutase and (or) hydroperoxidase were constructed by generalized transduction and their physiological responses to oxygen and oxidant stress examined, and both types of enzymes were required for an effective defense against chemical oxidants that generate superoxide radicals and hydrogen peroxide.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1988 journal article
Role of oxyradicals in the inactivation of catalase by ozone
Free Radical Biology and Medicine, 5(5-6), 305–312.
MeSH headings : Animals; Antioxidants / pharmacology; Buffers; Catalase / metabolism; Cattle; Enzyme Activation / drug effects; Free Radicals; Hydrogen-Ion Concentration; Ozone / pharmacology; Spectrophotometry; Water
TL;DR:
The data suggest the possible involvement of superoxide radicals in the inactivation of catalase by ozone and that SOD is less effective due to its inactivation by ozone.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
11. Sustainable Cities and Communities
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1988 journal article
Stability and expression of a plasmid-containing killer toxin cDNA in batch and chemostat cultures ofsaccharomyces cerevisiae
Biotechnology and Bioengineering, 31(8), 783–789.
TL;DR:
The effects of dilution rate, D(h−1) on plasmid stability and toxin expression were studied in transformed AH22 (AH22/T3) and Montrachet 522 (522/T1) wine yeast grown in glucose‐limited chemostat cultures and it was suggested that plasmids stability was dependent on the presence of the 2μ plasmide which is naturally present in some yeasts.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1988 conference paper
Superoxide dismutase: an antioxidant defense enzyme
UCLA Symposia on Molecular and Cellular Biology, 82, 183–193.
Source: NC State University Libraries
Added: March 12, 2022
1988 journal article
The role of redox in the regulation of manganese-containing superoxide dismutase biosynthesis in Escherichia coli.
Journal of Biological Chemistry, 263(9), 4269–4273.
TL;DR:
It is concluded that the redox state of the cell possibly influences the biosynthesis and/or activity of an iron-containing repressor protein that serves to negatively regulate manganese-superoxide dismutase biosynthesis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1988 journal article
Transcriptional regulation of katE in Escherichia coli K-12
Journal of Bacteriology, 170(9), 4286–4292.
MeSH headings : Aerobiosis; Anaerobiosis; Catalase / biosynthesis; Catalase / genetics; Cloning, Molecular; Enzyme Induction; Escherichia coli / enzymology; Escherichia coli / genetics; Escherichia coli / growth & development; Gene Expression Regulation; Genes, Bacterial; Hydrogen Peroxide / pharmacology; Mutation; Oxidation-Reduction; Transcription, Genetic; Transduction, Genetic
TL;DR:
Escherichia coli produces two distinct species of catalase, hydroperoxidases I and II, which differ in kinetic properties and regulation, and katE was fully expressed in air and was not further induced when the growth medium was sparged with 100% oxygen.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1987 journal article
Biosynthesis of superoxide dismutase and catalase in chemostat culture of Saccharomyces cerevisiae
Applied Microbiology and Biotechnology, 26(6), 531–536.
TL;DR:
The data clearly show that synthesis of SOD and catalase, though correlated with changes in oxygen tension, are independent of one another.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1987 journal article
Biosynthesis of superoxide dismutase in eight prokaryotes: Effects of oxygen, paraquat and an iron chelator
FEMS Microbiology Letters, 42(1), 33–38.
TL;DR:
The data indicate that the induction of S OD in P. vulgaris, E. cloacae, and Salmonella typhimurium is similar to that found in E. coli and suggest that the mechanism of SOD regulation inE.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1987 journal article
Effect of oxygen tension on stability and expression of a killer toxin chimeric plasmid in a chemostat culture of Saccharomyces cerevisiae
Applied Microbiology and Biotechnology, 27(1), 72–74.
TL;DR:
The effects of oxygen tension and dilution rate on expression and stability of killer toxin chimeric plasmid (pADH-10A) in transformants of wine yeast (Montrachet 522) were investigated using a glucose-limited chemostat culture.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1987 speech
Free Radicals in Health and Disease
Hassan, H. (1987, September). Workshop presented at the Symposium on Nutritional Impact of Food Processing, Reykjavik, Iceland.
Event: Symposium on Nutritional Impact of Food Processing at Reykjavik, Iceland on September 2-4, 1987
Source: NC State University Libraries
Added: March 12, 2022
1987 journal article
Induction and inactivation of catalase and superoxide dismutase of Escherichia coli by ozone
Archives of Biochemistry and Biophysics, 257(2), 464–471.
MeSH headings : Catalase / antagonists & inhibitors; Catalase / biosynthesis; Enzyme Induction; Escherichia coli / drug effects; Escherichia coli / enzymology; Escherichia coli / growth & development; Kinetics; Ozone / pharmacology; Superoxide Dismutase / antagonists & inhibitors; Superoxide Dismutase / biosynthesis
TL;DR:
Ozonation of cell-free extracts showed that superoxide dismutase and catalase are subject to oxidative inactivation by ozone, suggesting in vivo induction of these enzymes may represent an adaptive response evolved to protect cells against ozone toxicity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1987 journal article
Regulation of manganese-containing superoxide dismutase in Escherichia coli. Anaerobic induction by nitrate.
Journal of Biological Chemistry, 262(35), 17173–17177.
TL;DR:
The data support the previously proposed model for a negatively controlled operon where the repressor molecule is envisioned as an allosteric redox sensing protein and conditions known to oxidize or to deplete the iron are also found to cause induction of the manganese-superoxide dismutase albeit the absence of dioxygen.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1986 chapter
An alternate defense mechanism against paraquat toxicity in Escherichia coli
In G. Rotilio (Ed.), Superoxide and Superoxide Dismutase in Chemistry, Biology and Medicine (pp. 354–357). Elsevier Science.
Ed(s): G. Rotilio
Source: NC State University Libraries
Added: March 12, 2022
1986 journal article
Biosynthesis of superoxide dismutase and catalase inSaccharomyces cerevisiae: effects of oxygen and cytochromec deficiency
Journal of Industrial Microbiology, 1(3), 187–193.
TL;DR:
Two strains ofSaccharomyces cerevisiae were used to study the synthesis of superoxide dismutase, and the cytochromec-deficient mutant had lower specific growth rate, growth yield, and oxygen uptake than the wild type.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1986 journal article
Effects of cysteine on growth, protease production, and catalase activity of Pseudomonas fluorescens
Applied and Environmental Microbiology, 51(2), 418–421.
MeSH headings : Catalase / metabolism; Cysteine / pharmacology; Hydrogen Peroxide / pharmacology; Isoenzymes / metabolism; Kinetics; Peptide Hydrolases / biosynthesis; Pseudomonas fluorescens / drug effects; Pseudomonas fluorescens / enzymology; Pseudomonas fluorescens / growth & development
TL;DR:
Cysteine inhibits growth of and protease production by Pseudomonas fluorescens NC3 and suggests a role for the endogenous generation of hydrogen peroxide via the autoxidation of cysteine.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1986 chapter
Effects of cytochrome c deficiency, paraquat and copper on the biosynthesis of copper zinc superoxide dismutase and catalase in Saccharomyces cerevisiae
In G. Rotilio (Ed.), Superoxide and Superoxide Dismutase in Chemistry, Biology and Medicine (pp. 300–303). Elsevier Science.
Ed(s): G. Rotilio
Source: NC State University Libraries
Added: March 12, 2022
1986 chapter
Regulation of the synthesis of superoxide dismutase in procaryotes
In G. Rotilo (Ed.), Superoxide and Superoxide Dismutase in Chemistry, Biology and Medicine (pp. 274–279). Elsevier Science.
Ed(s): G. Rotilo
Source: NC State University Libraries
Added: March 12, 2022
1986 conference paper
Role of Superoxide Dismutase in Cellular Protection
Presented at the Frontiers in Basic Sciences that Relate to Heart, Lung, and Blood Diseases Symposium, Bethesda, MD.
Event: Frontiers in Basic Sciences that Relate to Heart, Lung, and Blood Diseases Symposium at Bethesda, MD on December 10-12, 1986
Source: NC State University Libraries
Added: March 12, 2022
1985 journal article
Biochemical characterization of a paraquat-tolerant mutant of Escherichia coli.
Journal of Biological Chemistry, 260(19), 10478–10481.
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1985 journal article
Biosynthesis of superoxide dismutase in Sacchromyces cerevisiae: Effects of paraquat and copper
Journal of Free Radicals in Biology & Medicine, 1(4), 319–325.
MeSH headings : Catalase / biosynthesis; Copper / pharmacology; Free Radicals; Kinetics; Oxygen Consumption / drug effects; Paraquat / pharmacology; Saccharomyces cerevisiae / drug effects; Saccharomyces cerevisiae / metabolism; Superoxide Dismutase / biosynthesis; Superoxides / metabolism
TL;DR:
A cytochrome c deficient mutant strain was found to be more responsive than the wild type strain to paraquat and/or copper by increasing its copper-zinc superoxide dismutase.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1985 journal article
Isolation of paraquat-resistant mutants ofEscherichia coli: lack of correlation between resistance and the activity of superoxide dismutase
FEMS Microbiology Letters, 28(1), 93–97.
TL;DR:
Resistance to paraquat in these mutant strains is, therefore, unrelated to their capacity to detoxify superoxide or hydrogen peroxide.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1985 chapter
Manipulation of Superoxide Dismutase Levels in Procaryotes
In R. Greenwald (Ed.), CRC Handbook of Methods for Oxygen Radical Research (pp. 353–358). Florida, US: CRC Press Inc.
Ed(s): R. Greenwald
Source: NC State University Libraries
Added: March 12, 2022
1985 journal article
Optimization of the hide powder azure assay for quantitating the protease of Pseudomonas fluorescens
Journal of Microbiological Methods, 4(2), 59–66.
TL;DR:
Protease production by P. fluorescens NC 3 was initiated during late-logarithmic-growth phase in a sodium caseinate medium and reached its maximum at the onset of the stationary phase.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1985 journal article
Regulation of the manganese-containing superoxide dismutase is independent of the inducible DNA repair system in Escherichia coli.
Journal of Biological Chemistry, 260(24), 12954–12956.
TL;DR:
Studies on the induction of the manganese-containing superoxide dismutase in several strains of Escherichia coli with different mutations in recA and lexA revealed that the inductions of the Mn-isozyme and of the SOS system by oxygen free radicals are not coregulated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1984 journal article
Anaerobic biosynthesis of the manganese containing superoxide dismutase in Escherichia coli
Journal of Biological Chemistry, 259(20), 12821–12825.
TL;DR:
A model is presented to account for the observed effects of oxygen, superoxide anion, and chelators on the increased synthesis of MnS OD and the regulatory repressor for MnSOD biosynthesis is envisioned as being an iron-containing protein.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: NC State University Libraries, NC State University Libraries
Added: March 12, 2022
1984 chapter
Chemistry and Biochemistry of Oxygen and of Its Partially Reduced Derivatives
In J. R. Totter, S. F. Gottlieb, & I. S. Longmuir (Eds.), Oxygen: An In Depth Study of Its Pathophysiology (pp. 307–340). Undersea Medical Society, Inc.
Ed(s): J. Totter, S. Gottlieb & I. Longmuir
Source: NC State University Libraries
Added: March 12, 2022
1984 journal article
Induction of the manganese-containing superoxide dismutase inEscherichia coliby nalidixic acid and by iron chelators
FEMS Microbiology Letters, 25(2-3), 233–236.
TL;DR:
2,2′-dipyridyl and 1,10-phenanthroline were shown to cause a 7- to 20-fold increase in the MnSOD of E. coli, and it is proposed that the repressor for MnS OD is an iron-containing protein.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1984 chapter
Oxygen toxicity in prokaryotes
In J. V. Bannister (Ed.), The Biology and Chemistry of Active Oxygen (pp. 128–138). North Holland: Elsevier.
Ed(s): J. Bannister
Source: NC State University Libraries
Added: March 12, 2022
1984 chapter
Superoxide Dismutase: An Antioxidant Defense Enzyme. In Free Radicals in Molecular Biology, Aging and Disease
In D. Armstrong, R. S. Sohal, R. G. Cutler, & T. F. Slater (Eds.), Free Radicals in Molecular Biology, Aging and Disease (pp. 77–85). NY: Raven Press.
Ed(s): D. Armstrong, R. Sohal, R. Cutler & T. Slater
Source: NC State University Libraries
Added: March 12, 2022
1984 journal article
Superoxide dismutase, catalase and peroxidase in four strains of Neisseria meningitidis of different virulence
FEMS Microbiology Letters, 25(1), 71–74.
TL;DR:
It was shown that the presence of catalase could yield an artifactual SOD-band when the SOD activity stain is performed in the presenceof 10 mM H2O2, normally required to inactivate and identify FeSODs.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1984 chapter
[30] Determination of the mutagenicity of oxygen free radicals using microbial systems
In L. Packer (Ed.), Oxygen Radicals in Biological Systems (pp. 254–263).
Ed(s): L. Packer
MeSH headings : Animals; Bacillus subtilis / drug effects; Biotransformation; Escherichia coli / drug effects; Free Radicals; Hydrogen Peroxide / toxicity; Hydroxides / toxicity; Hydroxyl Radical; Microsomes, Liver / metabolism; Mutagenicity Tests; Mutagens; Mutation; Saccharomyces cerevisiae / drug effects; Salmonella typhimurium / drug effects; Species Specificity; Superoxides / toxicity
TL;DR:
This chapter presents methods for assessing the mutagenicity of oxygen free radicals in microbial systems, usually rapid, simple, and inexpensive.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1984 chapter
[53] Determination of microbial damage caused by oxygen free radicals, and the protective role of superoxide dismutase
In L. Packer (Ed.), Oxygen Radicals in Biological Systems (pp. 404–412).
Ed(s): L. Packer
MeSH headings : Anaerobiosis; Animals; Anti-Bacterial Agents; Electron Transport; Enzyme Induction; Escherichia coli / drug effects; Escherichia coli / metabolism; Humans; Neutrophils / physiology; Oxygen / toxicity; Photolysis; Superoxide Dismutase / biosynthesis; Superoxide Dismutase / metabolism; Superoxides / metabolism; Superoxides / toxicity; Xanthine Oxidase / metabolism
TL;DR:
This chapter presents methods for generating oxygen free radicals, for manipulating the cellular concentration of SOD, and for assessing the damage caused by oxygenfree radicals.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1984 chapter
[69] Exacerbation of superoxide radical formation by Paraquat
In L. Packer (Ed.), Oxygen Radicals in Biological Systems (pp. 523–532).
Ed(s): L. Packer
MeSH headings : Animals; Cyanides / pharmacology; Escherichia coli / drug effects; Escherichia coli / metabolism; Free Radicals; Kinetics; NADP / metabolism; Oxidation-Reduction; Oxygen / metabolism; Oxygen Consumption / drug effects; Paraquat / radiation effects; Paraquat / toxicity; Pulse Radiolysis / methods; Superoxide Dismutase / metabolism; Superoxides / metabolism
TL;DR:
This chapter presents methods for measuring and identifying the partially reduced oxygen species generated during the reaction of PQ· + and O 2 .
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1983 speech
Antioxidant Enzymes and Aging
Hassan, H. (1983, October). Lecture presented at the 13th Annual Meeting of the American Aging Association, Washington, DC.
Event: 13th Annual Meeting of the American Aging Association at Washington, DC on October 6-8, 1983
Source: NC State University Libraries
Added: March 12, 2022
1983 speech
Oxygen
Hassan, H. (1983, June). Workshop presented at the Undersea Medical Society and the Institute of Energy Analysis Oak Ridge Associated Universities, Oak Ridge, TN.
Event: Undersea Medical Society and the Institute of Energy Analysis Oak Ridge Associated Universities at Oak Ridge, TN on June 30 - July 1, 1983
Source: NC State University Libraries
Added: March 12, 2022
1983 chapter
Oxygen toxicity and mutagenicity in procaryotes
In G. Cohen & R. Greenwald (Eds.), Oxy Radicals and Their scavengers Systems: Molecular Aspects (Vol. 1, pp. 198–206). Holland: Elsevier.
Ed(s): G. Cohen & R. Greenwald
Source: NC State University Libraries
Added: March 12, 2022
1982 journal article
Biosynthesis of oxygen-detoxifying enzymes in Bdellovibrio stolpii
Journal of Bacteriology, 152(2), 792–796.
MeSH headings : Aerobiosis; Bdellovibrio / enzymology; Catalase / biosynthesis; Isoenzymes / biosynthesis; Kinetics; Oxygen / metabolism; Oxygen Consumption; Peroxidase; Peroxidases / biosynthesis; Superoxide Dismutase / biosynthesis
TL;DR:
Induction of superoxide dismutase with 100% oxygen was manifested as an increase in the intensities of the two minor bands of activity, suggesting that isozyme I is constitutive, whereas isozymes II and III are inducible.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1982 chapter
Exacerbations of Oxygen Toxicity by Redox Active Compounds
In T. E. King, H. S. Mason, & M. Morrison (Eds.), Oxidases and Related Redox Systems (pp. 151–167).
Ed(s): T. King, H. Mason & M. Morrison
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1982 journal article
MUTAGENICITY OF OXYGEN FREE-RADICALS
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 79(9), 2855–2859.
MeSH headings : Catalase / metabolism; Free Radicals; Mutagenicity Tests; Mutagens; Oxygen; Paraquat / toxicity; Salmonella typhimurium / drug effects; Superoxide Dismutase / metabolism
TL;DR:
The mutagenicity of paraquat appears to be due to its ability to exacerbate the intracellular production of superoxide radicals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
1982 journal article
Superoxide dismutase protects against paraquat-mediated dioxygen toxicity and mutagenicity: studies in Salmonella typhimurium
Canadian Journal of Physiology and Pharmacology, 60(11), 1367–1373.
MeSH headings : Animals; Electron Transport; Enzyme Induction; Free Radicals; Humans; Mutagens / antagonists & inhibitors; Oxygen / antagonists & inhibitors; Oxygen / metabolism; Oxygen / toxicity; Paraquat / antagonists & inhibitors; Paraquat / toxicity; Salmonella typhimurium / drug effects; Salmonella typhimurium / genetics; Superoxide Dismutase / metabolism; Superoxide Dismutase / pharmacology
TL;DR:
Cells containing high levels of superoxide dismutase were more resistant to the toxic and mutagenic effects of paraquat than were cells containing a normal level of this enzyme.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1981 journal article
Chemistry and biochemistry of superoxide dismutases
European Journal of Rheumatology and Inflammation, 4, 160–172.
Source: NC State University Libraries
Added: March 12, 2022
1981 chapter
Superoxide and superoxide dismutases in Escherichia coli: threat and defense
In K. Bloch, L. Bolis, D. C. Tosteson, & J. Wright (Eds.), Membranes, Molecules, Toxins, and Cells (pp. 123–133). Boston: PSG Inc.
Ed(s): K. Bloch, L. Bolis, D. Tosteson & J. Wright
Source: NC State University Libraries
Added: March 12, 2022
1981 report
Vacuum Drum Planters
(Patent No. US4306509A).
Source: NC State University Libraries
Added: March 12, 2022
1980 chapter
Impermeability of the Escherichia coli cell envelope to superoxide radical
In W. H. Bannister & J. V. Bannister (Eds.), Developments in Biochemistry: Biological and Clinical Aspects of Superoxide and Superoxide Dismutase (Vol. 11B, pp. 57–71). North Holland: Elsevier North Holland.
Ed(s): W. Bannister & J. Bannister
Source: NC State University Libraries
Added: March 12, 2022
1980 journal article
Inhibitors of superoxide dismutases: A cautionary tale
Archives of Biochemistry and Biophysics, 199(2), 349–354.
MeSH headings : Animals; Cattle; Cytochrome c Group / metabolism; Dianisidine / metabolism; Enterococcus faecalis / enzymology; Erythrocytes / enzymology; Escherichia coli / enzymology; Metalloproteins / metabolism; Naphthols / pharmacology; Oxidation-Reduction; Superoxide Dismutase / antagonists & inhibitors; Superoxide Dismutase / blood
TL;DR:
It was shown that pamoic acid did not at all inhibit superoxide dismutase but rather diminished the sensitivity of the assays, and the mechanism proposed to account for this effect involved oxidation of pamoate, by O2−, to yield a pamoates radical which can then reduce cytochrome c or oxidize pyrogallol.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1980 journal article
Mechanism of the antibiotic action pyocyanine
Journal of Bacteriology, 141(1), 156–163.
MeSH headings : Catalase / biosynthesis; Enzyme Induction; Escherichia coli / drug effects; Escherichia coli / metabolism; Hydrogen Peroxide / metabolism; Isoenzymes; Oxygen / metabolism; Oxygen Consumption / drug effects; Phenazines / pharmacology; Pseudomonas aeruginosa / drug effects; Pyocyanine / pharmacology; Superoxide Dismutase / biosynthesis; Superoxides / metabolism
TL;DR:
It is concluded that pyocyanine diverts electron flow and thus increases the production of O2- and H2O2 and that the antibiotic action of this pigment is largely a reflection of the toxicity of these products of oxygen reduction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1980 chapter
Superoxide Dismutases
In D. Evered & G. Lawrenson (Eds.), Biological Roles of Copper (pp. 125–142).
Ed(s): D. Evered & G. Lawrenson
MeSH headings : Aerobiosis; Animals; Copper / analysis; Enzyme Induction; Escherichia coli / enzymology; Iron / analysis; Macromolecular Substances; Manganese / analysis; Protein Conformation; Species Specificity; Superoxide Dismutase / metabolism; Superoxides / pharmacology; Zinc / analysis
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1980 chapter
Superoxide Dismutases: Detoxication of a Free Radical
In W. B. Jakoby (Ed.), Enzymatic Basis of Detoxication (pp. 311–332).
Ed(s): W. Jakoby
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1980 speech
Superoxide and Superoxide Dismutases
Hassan, H. (1980, June). Mini symposium presented at the American Society of Biological Chemists Meeting, New Orleans, LA.
Event: American Society of Biological Chemists Meeting at New Orleans, LA on June 4, 1980
Source: NC State University Libraries
Added: March 12, 2022
1979 speech
Clinical Application of Superoxide Dismutase
Hassan, H. (1979, October). Presented at the Chemie Grunenthal GMBH, Aachen, West Germany.
Event: Chemie Grunenthal GMBH at Aachen, West Germany on October 19-20, 1979
Source: NC State University Libraries
Added: March 12, 2022
1979 journal article
Intracellular production of superoxide radical and of hydrogen peroxide by redox active compounds
Archives of Biochemistry and Biophysics, 196(2), 385–395.
MeSH headings : Catalase / metabolism; Cyanides / pharmacology; Electron Transport; Escherichia coli / drug effects; Escherichia coli / metabolism; Hydrogen Peroxide / metabolism; NAD / metabolism; Oxidation-Reduction; Oxygen / metabolism; Oxygen Consumption / drug effects; Subcellular Fractions / metabolism; Superoxide Dismutase / metabolism; Superoxides / metabolism
TL;DR:
The effect of alloxan appeared paradoxical in that it increased cyanide-resistant respiration without significantly increasing the cell content of the manganese-superoxide dismutase and with only a small effect on the level of catalase.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1979 chapter
Oxygen toxicity
In M. Shilo (Ed.), Strategy of Microbial Life in Extreme Environments (pp. 223–241). NY: Dahlem Konferenzen, Verlag Chemie.
Ed(s): M. Shilo
Source: NC State University Libraries
Added: March 12, 2022
1979 journal article
Paraquat and Escherichia coli. Mechanism of production of extracellular superoxide radical.
Journal of Biological Chemistry, 254(21), 10846–10852.
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1979 journal article
Paraquat and the exacerbation of oxygen toxicity
Trends in Biochemical Sciences, 4(5), 113–115.
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1979 chapter
Superoxide dismutase and its role for survival in the presence of oxygen
In M. Shilo (Ed.), Strategy of Microbial Life in Extreme Environments (pp. 179 193). NY: DahlemKonferenzen, Verlag Chemie [Wiley-VCH].
Ed(s): M. Shilo
Source: NC State University Libraries
Added: March 12, 2022
1979 journal article
Superoxide, Hydrogen Peroxide, and Oxygen Tolerance of Oxygen-Sensitive Mutants of Escherichia coli
Clinical Infectious Diseases, 1(2), 357–369.
MeSH headings : Escherichia coli / classification; Escherichia coli / drug effects; Escherichia coli / genetics; Hydrogen Peroxide / toxicity; Mutation; Oxygen / toxicity; Superoxide Dismutase / physiology; Superoxides / toxicity; Virulence
TL;DR:
The results indicated that enzymic scavenging of both H2O2 and O2- provides an important defense against oxygen toxicity.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1978 journal article
Regulation and Role of Superoxide Dismutase
Biochemical Society Transactions, 6(2), 356–361.
MeSH headings : Enzyme Induction; Escherichia coli / metabolism; Glucose / metabolism; Kinetics; Oxygen; Superoxide Dismutase / metabolism
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1978 journal article
Regulation of the synthesis of catalase and peroxidase in Escherichia coli.
Journal of Biological Chemistry, 253(18), 6445–6450.
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1978 speech
Strategies of Microbial Life in Extreme Environment
Hassan, H. (1978, November). Workshop presented at the Dahlem Konferenzen, Berlin, W. Germany.
Event: Dahlem Konferenzen at Berlin, W. Germany on November 20-24, 1978
Source: NC State University Libraries
Added: March 12, 2022
1978 journal article
Superoxide radical and the oxygen enhancement of the toxicity of paraquat in Escherichia coli.
Journal of Biological Chemistry, 253(22), 8143–8148.
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1977 journal article
Biochemical and physiological properties of alkaline phosphatases in five isolates of marine bacteria
Journal of Bacteriology, 129(3), 1607–1612.
MeSH headings : Alkaline Phosphatase / biosynthesis; Alkaline Phosphatase / metabolism; Bacteria / enzymology; Enzyme Repression; Isoenzymes / biosynthesis; Kinetics; Magnesium / pharmacology; Phosphates / pharmacology; Seawater; Species Specificity
TL;DR:
The alkaline phosphatase activities of five unique isolates of marine bacteria were found to be associated with the periplasmic space; however, the enzymes from these isolates differed with respect to their repressibility, the apparent number of isoenzymes, the necessity for Mg2 for activity, and the conditions required for their release.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1977 journal article
Enzymatic defenses against the toxicity of oxygen and of streptonigrin in Escherichia coli
Journal of Bacteriology, 129(3), 1574–1583.
MeSH headings : Anaerobiosis; Catalase / biosynthesis; Chloramphenicol / pharmacology; Enzyme Induction / drug effects; Escherichia coli / drug effects; Escherichia coli / enzymology; Escherichia coli / ultrastructure; Isoenzymes / biosynthesis; Oxygen / toxicity; Peroxidases / biosynthesis; Puromycin / pharmacology; Streptonigrin / toxicity; Superoxide Dismutase / biosynthesis
TL;DR:
Anaerobically grown Escherichia coli K-12 cells showed a much greater oxygen enhancement of the lethality of streptonigrin than did aerobically growing cells, in accord with the proposal that streptonigratedin can serve as an intracellular source of superoxide.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1977 journal article
Physiological function of superoxide dismutase in glucose-limited chemostat cultures of Escherichia coli
Journal of Bacteriology, 130(2), 805–811.
MeSH headings : Escherichia coli / drug effects; Escherichia coli / enzymology; Escherichia coli / growth & development; Free Radicals; Glucose / metabolism; Isoenzymes / analysis; Oxygen / pharmacology; Oxygen Consumption; Streptonigrin / pharmacology; Superoxide Dismutase / analysis; Superoxide Dismutase / physiology; Superoxides / metabolism
TL;DR:
Conditions for continuous culture of Escherichia coli K-12 His- Thi- under glucose limitation were established, and results indicated a progressive deficiency of reducing power at growth rates below 0.25/h and a surfeit of reducingPower with progressively greater protection against O2- by superoxide dismutase at growth rate greater than 0.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1977 journal article
Regulation of superoxide dismutase synthesis in Escherichia coli: glucose effect
Journal of Bacteriology, 132(2), 505–510.
MeSH headings : Cyclic AMP / metabolism; Enzyme Repression; Escherichia coli / enzymology; Escherichia coli / metabolism; Fermentation; Glucose / metabolism; Hydrogen-Ion Concentration; Methylglucosides / pharmacology; Paraquat / pharmacology; Superoxide Dismutase / biosynthesis
TL;DR:
It appears likely that superoxide dismutase is controlled directly or indirectly by the intracellular level of O2- and that glucose depressed the level of this enzyme because glucose metabolism is not associated with as rapid a production of O 2- as is the metabolsim of many other substances.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1977 journal article
Regulation of the synthesis of superoxide dismutase in Escherichia coli. Induction by methyl viologen.
Journal of Biological Chemistry, 252(21), 7667–7672.
TL;DR:
It seems likely that paraquat subverts a portion of the normal, cyanide-sensitive, electron flow in the cells and transfers that electron flow to oxygen, in an increased rate of intracellular production of O,-, then induces or derepresses the biosynthesis of the manganese-superoxide dismutase, which defends the cell against the deleterious reactivities of this radical.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1976 journal article
Diminution of outer membrane permeability by Mg2+ in a marine pseudomonad
Journal of Bacteriology, 125(3), 910–915.
MeSH headings : Alkaline Phosphatase / metabolism; Cell Membrane Permeability / drug effects; Cell-Free System; Kinetics; Nitrophenols; Organophosphates / metabolism; Pseudomonas / enzymology; Pseudomonas / metabolism; Seawater; Sodium Chloride / pharmacology; Water Microbiology
TL;DR:
Intact cells of the marine pseudomonad MB-45, in the presence of optimal Mg2+, exhibited little alkaline phosphatase activity as judged by the hydrolysis of p-nitrophenylphosphate, but Sonic extracts, in contrast, were rich in this activity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1975 chapter
Characterization of methane production from poultry manure
In Managing Livestock Wastes (pp. 244–247, 251). American Society of Agricultural Engineers.
Source: NC State University Libraries
Added: March 12, 2022
1975 chapter
Energy recovery and feed production from poultry waste
In W. J. Jewell (Ed.), Energy, Agriculture and Waste Management (pp. 289–305). Michigan, US: Ann Arbor Science Publishers Inc.
Ed(s): W. Jewell
Source: NC State University Libraries
Added: March 12, 2022
1975 journal article
Kinetics of Na+-dependent K+ ion transport in a marine pseudomonad
Journal of Bacteriology, 121(1), 160–164.
MeSH headings : Biological Transport, Active; Cell Membrane / metabolism; Kinetics; Potassium / metabolism; Potassium Isotopes; Pseudomonadaceae / metabolism; Radioisotopes; Seawater; Sodium / metabolism; Water Microbiology
TL;DR:
The results suggest that Na plus and K plus form a ternary complex with a specific K plus carrier molecule on the outer surface of the membrane prior to translocation and the release of K plus inside the cell.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1975 journal article
The resistance of Pseudomonas aeruginosa to chloramphenicol
Canadian Journal of Microbiology, 21(8), 1185–1191.
MeSH headings : Acetylation; Acridines / pharmacology; Acyltransferases / biosynthesis; Chloramphenicol / metabolism; Chloramphenicol / pharmacology; Drug Resistance, Microbial / drug effects; Genetic Variation; Mitomycins / pharmacology; Pseudomonas aeruginosa / drug effects; Pseudomonas aeruginosa / growth & development; Pseudomonas aeruginosa / metabolism; Pyocyanine / biosynthesis; R Factors / drug effects; Sodium Dodecyl Sulfate / pharmacology
TL;DR:
The results suggest that the resistant strain inactivates CM by acetylation and, in addition, develops a "permeability" barrier towards chloramphenicol.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 15, 2021
1973 journal article
Effect of milk solids concentration on buffalo and cow soft cheese
Alexandria Journal of Agricultural Research, 21, 383–389.
Source: NC State University Libraries
Added: March 12, 2022
1973 journal article
Some technological aspects of buffalo and cow soft cheese
Alexandria Journal of Agricultural Research, 21, 391–396.
Source: NC State University Libraries
Added: March 12, 2022
1969 journal article
Effects of Selected Food Additives on Growth of Pseudomonas fragi
Journal of Dairy Science, 52(3), 335–340.
MeSH headings : Bacitracin / pharmacology; Benzoates / pharmacology; Chloramphenicol / pharmacology; Dairy Products; Edetic Acid / pharmacology; Food Additives / pharmacology; Food Microbiology; Food Preservation; Muramidase / pharmacology; Nitrofurazone / pharmacology; Pseudomonas / drug effects; Pseudomonas / growth & development; Tetracycline / pharmacology
TL;DR:
Tests of inhibition of Pseudomonas fragi in lactose-yeast extract broth by the food additives chlortctraeycline, nisin, bacitracin, chloramphenicol, lysozyme, ethylenediaminetetraacetic acid (EDTA), nitrofurazone, propyl-p-hydroxybenzoate, sodium benzoates, and potassium sorbate found them ineffective.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1969 journal article
Molar Growth Yield of Streptococcus faecalis on Pyruvate
Journal of Bacteriology, 97(3), 1496–1497.
MeSH headings : Culture Media; Enterococcus faecalis / growth & development; Enterococcus faecalis / metabolism; Glucose / metabolism; Pyruvates / metabolism
TL;DR:
Y(pyruvate) was 17.3, similar to Y(arginine), for Streptococcus faecalis 6783 grown statically in a complex medium in 1 atm of air.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1969 journal article
Sensory and Shelf-Life Evaluations of Cottage Cheese Treated with Potassium Sorbate
Journal of Dairy Science, 52(4), 439–442.
MeSH headings : Antifungal Agents; Dairy Products; Food Preservation; Potassium
TL;DR:
These amounts of potassium sorbate retarded growth of bacteria that produced fruity and putrid odors and slime in Cottage cheese at refrigeration temperatures andacteria that produced sourness and molds.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1968 journal article
Molar Growth Yields of Certain Lactic Acid Bacteria as Influenced by Autolysis
Journal of Bacteriology, 96(1), 117–125.
MeSH headings : Adenosine Triphosphate / metabolism; Arginine / metabolism; Bacteriological Techniques; Bacteriolysis; Culture Media; Enterococcus faecalis / growth & development; Enterococcus faecalis / metabolism; Glucose / metabolism; Streptococcus / growth & development; Streptococcus / metabolism
TL;DR:
Molar growth yields determined from batch cultures of Streptococcus diacetilactis and S. faecalis were appreciably greater at the peaks of maximal growth than after continued incubation and considerable autolysis.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
1968 journal article
Role of Galactose or Glucose-1-Phosphate in Preventing the Lysis of Streptococcus diacetilactis
Journal of Bacteriology, 95(2), 592–602.
MeSH headings : Bacterial Proteins / analysis; Bacteriolysis; Chloramphenicol / pharmacology; Galactose / metabolism; Glucose / metabolism; Hexosamines / metabolism; Hexosephosphates / metabolism; Hydrogen-Ion Concentration; Lactose / metabolism; Maltose / metabolism; Osmosis; Streptococcus / metabolism; Temperature
TL;DR:
The results indicate that the organism phosphorolyzes maltose to glucose plus beta-glucose-1-phosphate, and suggest that it can use the beta- glucose -1- phosphate in place of alpha-glUCose- 1-ph phosphate in the formation of cell materials.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 13, 2021
Employment
Updated: January 18th, 2023 12:40
1980 - present
North Carolina State University Raleigh, North Carolina, US
Professor of Microbiology, Biochemistry, Food Science, and Toxicology
Poultry Science
Education
Updated: January 18th, 2023 12:45
1962 - 1967
University of California Davis Department of Microbiology and Molecular Genetics Davis, CA, US
Ph.D.
Microbiology
Funding History
Funding history based on the linked ORCID record. Updated: January 18th, 2023 13:02
grant
July 1, 2012 - June 1, 2018
Development of Novel Salmonella control Practices and Integrated Education Program to Reduce Salmonellosis
USDA-NIFA
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