Hayden Nathaniel Brochu

Works (8)

Updated: July 8th, 2023 21:14
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2022 journal article

Alternative splicing and genetic variation of mhc-e: implications for rhesus cytomegalovirus-based vaccines

COMMUNICATIONS BIOLOGY, 5(1).

By: H. Brochu n, R. Wang *, T. Tollison n, C. Pyo*, A. Thomas *, E. Tseng *, L. Law *, L. Picker * ...

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Humans; Alternative Splicing; Cytomegalovirus; Cytomegalovirus Vaccines; Genetic Variation; Macaca mulatta; Simian Immunodeficiency Virus; Histocompatibility Antigens Class I / genetics
Sources: Web Of Science, ORCID
Added: January 17, 2023

2022 journal article

Phylogeny-guided microbiome OTU-specific association test (POST)

MICROBIOME, 10(1).

By: C. Huang  n, B. Callahan n , M. Wu *, S. Holloway n, H. Brochu n, W. Lu n, X. Peng n , J. Tzeng n

co-author countries: United States of America 🇺🇸
author keywords: Association test; Phylogenetic tree; Kernel machine regression
MeSH headings : Computational Biology / methods; Computer Simulation; Female; Humans; Infant, Newborn; Microbiota / genetics; Phylogeny; Premature Birth
Sources: Web Of Science, ORCID
Added: June 20, 2022

2022 journal article

Single-Cell-Based High-Throughput Ig and TCR Repertoire Sequencing Analysis in Rhesus Macaques

JOURNAL OF IMMUNOLOGY, 208(3), 762–771.

By: E. Walsh n, T. Tollison n, H. Brochu n, B. Shaw *, K. Diveley n, H. Chou n, L. Law *, A. Kirk *, M. Gale *, X. Peng n 

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Gene Expression Profiling; High-Throughput Nucleotide Sequencing; Immunoglobulins / genetics; Macaca mulatta; Receptors, Antigen, T-Cell, alpha-beta / genetics; Receptors, Antigen, T-Cell, gamma-delta / genetics; Single-Cell Analysis; T-Lymphocytes / immunology; Transcriptome / genetics; VDJ Exons / genetics
Sources: Web Of Science, ORCID
Added: February 28, 2022

2021 journal article

Tumor Necrosis Factor Alpha-Induced Interleukin-1 Alpha Synthesis and Cell Death Is Increased in Mouse Epithelial Cells Infected With Chlamydia muridarum

JOURNAL OF INFECTIOUS DISEASES, 224, S47–S55.

By: U. Nagarajan*, C. Cho *, C. Gyorke*, S. Nagarajan*, J. Ezzell *, H. Brochu n, I. Huntress n, E. Harrell n, X. Peng n 

co-author countries: United States of America 🇺🇸
author keywords: Chlamydia muridarum; IL-1 alpha; mouse epithelial cells; mouse model; TNF alpha
MeSH headings : Animals; Cell Death; Chlamydia Infections / immunology; Chlamydia Infections / metabolism; Chlamydia muridarum / immunology; Epithelial Cells; Female; Interleukin-1alpha / immunology; Interleukin-1alpha / metabolism; Mice; Mice, Inbred C57BL; Tumor Necrosis Factor-alpha / immunology; Tumor Necrosis Factor-alpha / metabolism
Sources: Web Of Science, ORCID
Added: September 13, 2021

2020 journal article

Inhalation of lung spheroid cell secretome and exosomes promotes lung repair in pulmonary fibrosis

NATURE COMMUNICATIONS, 11(1).

By: P. Dinh n, D. Paudel n, H. Brochu n, K. Popowski n , M. Gracieux n, J. Cores n, K. Huang n , M. Hensley n ...

co-author countries: United States of America 🇺🇸
MeSH headings : Administration, Inhalation; Alveolar Epithelial Cells / drug effects; Alveolar Epithelial Cells / metabolism; Alveolar Epithelial Cells / pathology; Animals; Apoptosis / drug effects; Bleomycin / toxicity; Cell Proliferation; Disease Models, Animal; Exosomes / metabolism; Exosomes / transplantation; Humans; Idiopathic Pulmonary Fibrosis / chemically induced; Idiopathic Pulmonary Fibrosis / metabolism; Idiopathic Pulmonary Fibrosis / pathology; Idiopathic Pulmonary Fibrosis / therapy; Lung / cytology; Lung / metabolism; Lung Injury / chemically induced; Lung Injury / metabolism; Lung Injury / pathology; Lung Injury / therapy; Mesenchymal Stem Cells / metabolism; Mice; Myofibroblasts / cytology; Proteomics; Silicon Dioxide / toxicity; Spheroids, Cellular / metabolism
Sources: Web Of Science, ORCID
Added: March 23, 2020

2020 journal article

Systematic Profiling of Full-Length Ig and TCR Repertoire Diversity in Rhesus Macaque through Long Read Transcriptome Sequencing

JOURNAL OF IMMUNOLOGY, 204(12), 3434–3444.

By: H. Brochu n, E. Tseng, E. Smith*, M. Thomas*, A. Jones n, K. Diveley n, L. Law *, S. Hansen * ...

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; High-Throughput Nucleotide Sequencing / methods; Humans; Immunoglobulins / genetics; Immunoglobulins / immunology; Macaca mulatta / genetics; Macaca mulatta / immunology; Receptors, Antigen, T-Cell / immunology; Transcriptome / genetics; Transcriptome / immunology
Sources: Web Of Science, ORCID
Added: July 6, 2020

2019 journal article

Simultaneous profiling of sexually transmitted bacterial pathogens, microbiome, and concordant host response in cervical samples using whole transcriptome sequencing analysis

MICROBIAL CELL, 6(3), 177–183.

By: . Catherine M. O'Connell *, H. Brochu n, J. Girardi*, E. Harrell n, A. Jones n, T. Darville *, A. Sena *, X. Peng n 

co-author countries: United States of America 🇺🇸
author keywords: RNA-seq; chlamydia; gonorrhea; natural infection; microbiome
Sources: Web Of Science, ORCID
Added: March 18, 2019

2017 review

Elucidating the role of host long non-coding RNA during viral infection: Challenges and paths forward

[Review of ]. Vaccines, 5(4).

By: D. Lemler, H. Brochu, F. Yang, E. Harrell & X. Peng 

Source: NC State University Libraries
Added: August 6, 2018