Works (4)

Updated: September 12th, 2023 05:01

2023 journal article

A Ferric-Superoxide Intermediate Initiates P450-Catalyzed Cyclic Dipeptide Dimerization

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 8.

By: H. Gering n, X. Li n, H. Tang n, P. Swartz n, W. Chang n & T. Makris n

co-author countries: United States of America 🇺🇸
Sources: Web Of Science, ORCID
Added: September 11, 2023

2022 journal article

Mechanistic analysis of carbon-carbon bond formation by deoxypodophyllotoxin synthase

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 119(1).

By: H. Tang n, M. Wu*, H. Lin*, M. Han*, Y. Tu*, Z. Yang*, T. Chien*, N. Chan*, W. Chang n

co-author countries: Taiwan, Province of China 🇹🇼 United States of America 🇺🇸
author keywords: C-C coupling; cyclization; oxygenase; natural product; reaction mechanism
MeSH headings : Berberidaceae / enzymology; Drugs, Chinese Herbal / chemistry; Ligases / chemistry; Oxidation-Reduction; Plant Proteins / chemistry; Podophyllotoxin / analogs & derivatives; Podophyllotoxin / chemistry
Sources: Web Of Science, ORCID
Added: February 21, 2022

2021 article

BesC Initiates C-C Cleavage through a Substrate-Triggered and Reactive Diferric-Peroxo Intermediate

Manley, O. M., Tang, H., Xue, S., Guo, Y., Chang, W.-chen, & Makris, T. M. (2021, December 13). JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol. 12.

co-author countries: United States of America 🇺🇸
MeSH headings : Carbon / chemistry; Carbon / metabolism; Ferric Compounds / chemistry; Oxidoreductases / metabolism; Oxygen / chemistry; Spectroscopy, Mossbauer; Streptomyces / enzymology; Substrate Specificity
Sources: Web Of Science, ORCID
Added: January 3, 2022

2021 journal article

Harnessing the Substrate Promiscuity of Dioxygenase AsqJ and Developing Efficient Chemoenzymatic Synthesis for Quinolones

ACS CATALYSIS, 11(12), 7186–7192.

By: H. Tang n, Y. Tang*, I. Kurnikov*, H. Liao*, N. Chan*, M. Kurnikova*, Y. Guo*, W. Chang n

co-author countries: Taiwan, Province of China 🇹🇼 United States of America 🇺🇸
author keywords: Fe/2OG enzyme; AsqJ; chemoenzymatic synthesis; rearrangement; quinolone
Sources: Web Of Science, ORCID
Added: July 19, 2021