Hong Wang

Assembly path dependence of telomeric DNA compaction by TRF1, TIN2, and SA1

BIOPHYSICAL JOURNAL, 122(10), 1822–1832.

PARP1 associates with R-loops to promote their resolution and genome stability

Laspata, N., Kaur, P., Mersaoui, S. Y., Muoio, D., Liu, Z. S., Bannister, M. H., … Fouquerel, E. (2023, February 16). NUCLEIC ACIDS RESEARCH, Vol. 2.

Single-molecule imaging of genome maintenance proteins encountering specific DNA sequences and structures

DNA REPAIR, 128.

Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA

Wojtaszek, J. L., Hoff, K. E., Longley, M. J., Kaur, P., Andres, S. N., Wang, H., … Copeland, W. C. (2023, August 18). NUCLEIC ACIDS RESEARCH, Vol. 8.

Densely methylated DNA traps Methyl-CpG-binding domain protein 2 but permits free diffusion by Methyl-CpG-binding domain protein 3

JOURNAL OF BIOLOGICAL CHEMISTRY, 298(10).

Structural and dynamic basis of DNA capture and translocation by mitochondrial Twinkle helicase

Li, Z., Kaur, P., Lo, C.-Y., Chopra, N., Smith, J., Wang, H., & Gao, Y. (2022, November 18). NUCLEIC ACIDS RESEARCH, Vol. 11.

Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA

JOURNAL OF BIOLOGICAL CHEMISTRY, 297(3).

Structure, dynamics, and regulation of TRF1-TIN2-mediated trans-and cis-interactions on telomeric DNA

Journal of Biological Chemistry, 101080.

TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA

NUCLEIC ACIDS RESEARCH, 49(22), 13000–13018.

Using Atomic Force Microscopy to Study the Real Time Dynamics of DNA Unwinding by Mitochondrial Twinkle Helicase

BIO-PROTOCOL, 11(17).

Cohesin SA1 and SA2 are RNA binding proteins that localize to RNA containing regions on DNA

NUCLEIC ACIDS RESEARCH, 48(10), 5639–5655.

Cohesin SA1 and SA2 are RNA binding proteins that localize to RNA containing regions on DNA

Nucleic Acids Research.

DNA looping by two 5-methylcytosine-binding proteins quantified using nanofluidic devices

EPIGENETICS & CHROMATIN, 13(1).

Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase

JOURNAL OF BIOLOGICAL CHEMISTRY, 295(17), 5564–5576.

Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase

Journal of Biological Chemistry, 295(17), 5564–5576.

Cohesin SA2 and EWSR1 in R-Loop Regulation

Biophysical Journal, 116(3), 505a.

Measuring UV Photoproduct Repair in Isolated Telomeres and Bulk Genomic DNA

DNA REPAIR: METHODS AND PROTOCOLS, Vol. 1999, pp. 295–306.

Measuring UV Photoproduct Repair in Isolated Telomeres and Bulk Genomic DNA

In DNA Repair (pp. 295–306). Springer.

Single-Molecule Study of TRF2 Mediated DNA Compaction using Physiologically Relevant Long Telomeric DNA

Biophysical Journal, 116(3), 505a.

TIN2 is an Architectural Protein Stabilizing TRF1 at Telomere

Biophysical Journal, 116(3), 211a–212a.

Cohesin SA2 is a sequence-independent DNA-binding protein that recognizes DNA replication and repair intermediates

JOURNAL OF BIOLOGICAL CHEMISTRY, 293(3), 1054–1069.

Single-molecule DREEM imaging reveals DNA wrapping around human mitochondrial single-stranded DNA binding protein

NUCLEIC ACIDS RESEARCH, 46(21), 11287–11302.

Cohesin SA2 is a sequence independent DNA binding protein that recognizes DNA replication and repair intermediates

Journal of Biological Chemistry, jbc-M117.

CpG and methylation-dependent DNA binding and dynamics of the methylcytosine binding domain 2 protein at the single-molecule level

NUCLEIC ACIDS RESEARCH, 45(15), 9164–9177.

Nucleosome-like, Single-stranded DNA (ssDNA)-Histone Octamer Complexes and the Implication for DNA Double Strand Break Repair

Journal of Biological Chemistry, 292(13), 5271–5281.

Single Molecule Fluorescence and Atomic Force Microscopy Studies of DNA Repair

Biophysical Journal, 112(3), 7a.

Using Atomic Force Microscopy to Characterize the Conformational Properties of Proteins and Protein--DNA Complexes That Carry Out DNA Repair

Methods in Enzymology, 592, 187–212.

Walking the DNA Methylation Tightrope: The Involvement of Intrinsically Disordered Regions of Transcription Factors

Biophysical Journal, 112(3), 207a.

Enhanced electrostatic force microscopy reveals higher-order DNA looping mediated by the telomeric protein TRF2

Scientific Reports, 6(1).

Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA--DNA pairing

Nucleic Acids Research, gkw518.

Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA-DNA pairing

NUCLEIC ACIDS RESEARCH, 44(13), 6363–6376.

TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection

Molecular Cell.

TRF2-mediated control of telomere DNA topology as a mechanism for chromosome-end protection

Molecular Cell, 61(2), 274–286.

Visualizing the Path of DNA through Proteins Using DREEM Imaging

MOLECULAR CELL, 61(2), 315–323.

Determining the DNA Diffusion Behavior of SA2 on Various DNA Substrates

Biophysical Journal, 108(2), 397a.

Interference of ATP with the fluorescent probes YOYO-1 and YOYO-3 modifies the mechanical properties of intercalator-stained DNA confined in nanochannels

Microchimica Acta, 182(7-8), 1561–1565.

Revealing Structure and Dynamics of Telomere Maintenance Proteins on DNA: One Molecule at a Time

Biophysical Journal, 108(2), 7a.

Single-Molecule Imaging Reveals Dynamics of SA1-TRF1 Interactions on Telomeric DNA

Biophysical Journal, 108(2), 206a.

Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts

NATURE COMMUNICATIONS, 6.

Probing transient protein-mediated DNA linkages using nanoconfinement

Biomicrofluidics, 8(3), 034113.

Single-molecule analysis reveals human UV-damaged DNA-binding protein (UV-DDB) dimerizes on DNA via multiple kinetic intermediates

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111(18), E1862–E1871.

Single-molecule imaging reveals DNA-binding properties of cohesin proteins SA1 and SA2.

Environmental and Molecular Mutagenesis, 55, S29–29.

TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres

NUCLEIC ACIDS RESEARCH, 42(4), 2493–2504.

TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres

Nucleic Acids Research, 42(4), 2493–2504.

Unraveling secrets of telomeres: One molecule at a time

DNA REPAIR, 20, 142–153.

DNA polymerase delta stalls on telomeric lagging strand templates independently from G-quadruplex formation

NUCLEIC ACIDS RESEARCH, 41(22), 10323–10333.

Investigating bioconjugation by atomic force microscopy

[Review of ]. Journal of Anobiotechnology, 11.

Investigating bioconjugation by atomic force microscopy

J. Nanobiotechnol, 11, 25.

Real-time single-molecule imaging reveals a direct interaction between UvrC and UvrB on DNA tightropes

Nucleic Acids Research, gkt177.

WT UV-DDB Performs a 3D Search on DNA whereas the XP-E Mutant (K244E DDB2) Mutant Slides

Biophysical Journal, 104(2), 77a.

A New Role for UvrB in NER? Single Molecule Imaging of the NER Complex UvrBC-DNA

Biophysical Journal, 102(3), 485a.

Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair

Proceedings of the National Academy of Sciences, 109(41), E2737–E2746.

Werner syndrome protein suppresses the formation of large deletions during the replication of human telomeric sequences

Cell Cycle, 11(16), 3036–3044.

High accuracy FIONA–AFM hybrid imaging

Ultramicroscopy, 111(5), 350–355.

Investigating Nucleotide Excision DNA Repair by Single-Molecule Imaging of Quantum Dot Labeled Proteins Reveals Unique Scanning Mechanisms

Biophysical Journal, 100(3), 240a.

Nucleotide excision repair from bacteria to humans: Structure--function studies

In Chemical Carcinogenesis (pp. 267–296). Springer.

Single Molecule Studies of Physiologically Relevant Telomeric Tails Reveal POT1 Mechanism for Promoting G-quadruplex Unfolding

Journal of Biological Chemistry, 286(9), 7479–7489.

Collaborative Dynamic DNA Scanning by Nucleotide Excision Repair Proteins Investigated by Single- Molecule Imaging of Quantum-Dot-Labeled Proteins

Molecular Cell, 37(5), 702–713.

Replication Protein A Stimulates the Werner Syndrome Protein Branch Migration Activity

Journal of Biological Chemistry, 284(50), 34682–34691.

The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation

PLoS One, 4(3), e4825.

Efficient processing of TFO-directed psoralen DNA interstrand crosslinks by the UvrABC nuclease

Nucleic Acids Research, 36(22), 7136–7145.

Functional Characterization and Atomic Force Microscopy of a DNA Repair Protein Conjugated to a Quantum Dot

Nano Letters, 8(6), 1631–1637.

Characterization of protein--protein interactions using atomic force microscopy

In Protein Interactions (pp. 39–77). Springer.

Structural basis for DNA recognition and processing by UvrB

Nature Structural & Molecular Biology, 13(4), 360–364.

The C-terminal Zinc Finger of UvrA Does Not Bind DNA Directly but Regulates Damage-specific DNA Binding

Journal of Biological Chemistry, 281(36), 26370–26381.

UvrB Domain 4, an Autoinhibitory Gate for Regulation of DNA Binding and ATPase Activity

Journal of Biological Chemistry, 281(22), 15227–15237.

Structural insights into the first incision reaction during nucleotide excision repair

The EMBO Journal, 24(5), 885–894.

Structural insights into the first incision reaction during nucleotide excision repair

The EMBO Journal, 24(5), 885–894.

‘Close-fitting sleeves’: DNA damage recognition by the UvrABC nuclease system

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 577(1-2), 92–117.

DNA bending and unbending by MutS govern mismatch recognition and specificity

Proceedings of the National Academy of Sciences, 100(25), 14822–14827.

Functional oligomeric state of avian sarcoma virus integrase

Journal of Biological Chemistry, 278(2), 1323–1327.

Quantitative characterization of biomolecular assemblies and interactions using atomic force microscopy

Methods, 29(2), 175–187.

A minimal exonuclease domain of WRN forms a hexamer on DNA and possesses both 3'-5'exonuclease and 5'-protruding strand endonuclease activities

Biochemistry, 41(9), 2901–2912.

DNA binding properties of the yeast Msh2-Msh6 and Mlh1-Pms1 heterodimers

Biological Chemistry, 383(6), 969–975.

High affinity cooperative DNA binding by the yeast Mlh1-Pms1 heterodimer

Journal of Molecular Biology, 312(4), 637–647.