Works (60)

2021 journal article

Structure, dynamics, and regulation of TRF1-TIN2-mediated trans-and cis-interactions on telomeric DNA

Journal of Biological Chemistry, 101080.

By: H. Pan, P. Kaur, R. Barnes, A. Detwiler, S. Sanford, M. Liu, P. Xu, C. Mahn ...

Source: ORCID
Added: September 23, 2021

2021 journal article

Using Atomic Force Microscopy to Study the Real Time Dynamics of DNA Unwinding by Mitochondrial Twinkle Helicase

BIO-PROTOCOL, 11(17), e4139–e4139.

By: P. Kaur, H. Pan, M. Longley, W. Copeland & H. Wang

Sources: Web Of Science, ORCID
Added: September 20, 2021

2020 journal article

Cohesin SA1 and SA2 are RNA binding proteins that localize to RNA containing regions on DNA

NUCLEIC ACIDS RESEARCH, 48(10), 5639–5655.

By: H. Pan, M. Jin, A. Ghadiyaram, P. Kaur, H. Miller, H. Ta, M. Liu, Y. Fan ...

Source: Web Of Science
Added: October 5, 2020

2020 journal article

Cohesin SA1 and SA2 are RNA binding proteins that localize to RNA containing regions on DNA

Nucleic Acids Research.

By: H. Pan, M. Jin, A. Ghadiyaram, P. Kaur, H. Miller, H. Ta, M. Liu, Y. Fan ...

Source: ORCID
Added: September 23, 2021

2020 journal article

DNA looping by two 5-methylcytosine-binding proteins quantified using nanofluidic devices

EPIGENETICS & CHROMATIN, 13(1), 1–10.

By: M. Liu, S. Movahed, S. Dangi, H. Pan, P. Kaur, S. Bilinovich, E. Faison, G. Leighton ...

Sources: Web Of Science, ORCID
Added: April 20, 2020

2020 journal article

Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase

JOURNAL OF BIOLOGICAL CHEMISTRY, 295(17), 5564–5576.

By: P. Kaur, M. Longley, H. Pan, W. Wang, P. Countryman, H. Wang, W. Copeland

Source: Web Of Science
Added: May 18, 2020

2020 journal article

Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase

Journal of Biological Chemistry, 295(17), 5564–5576.

By: P. Kaur, M. Longley, H. Pan, W. Wang, P. Countryman, H. Wang, W. Copeland

Source: ORCID
Added: September 23, 2021

2019 journal article

Cohesin SA2 and EWSR1 in R-Loop Regulation

Biophysical Journal, 116(3), 505a.

By: H. Wang, A. Ghadiyaram, H. Pan, Y. Fan, P. Kaur, A. Gorthi, R. Riehn, A. Bishop, Y. Jane Tao

Sources: Crossref, ORCID
Added: December 18, 2020

2019 article

Measuring UV Photoproduct Repair in Isolated Telomeres and Bulk Genomic DNA

DNA REPAIR: METHODS AND PROTOCOLS, pp. 295–306.

By: E. Fouquerel, R. Barnes, H. Wang & P. Opresko

Source: Web Of Science
Added: October 7, 2019

2019 chapter

Measuring UV Photoproduct Repair in Isolated Telomeres and Bulk Genomic DNA

In DNA Repair (pp. 295–306). Springer.

By: E. Fouquerel, R. Barnes, H. Wang & P. Opresko

Source: ORCID
Added: September 23, 2021

2019 journal article

Single-Molecule Study of TRF2 Mediated DNA Compaction using Physiologically Relevant Long Telomeric DNA

Biophysical Journal, 116(3), 505a.

By: P. Kaur, R. Barnes, H. Pan, P. Opresko, R. Riehn & H. Wang

Sources: Crossref, ORCID
Added: December 18, 2020

2019 journal article

TIN2 is an Architectural Protein Stabilizing TRF1 at Telomere

Biophysical Journal, 116(3), 211a–212a.

By: H. Pan, S. Dangi, P. Kaur, P. Hao, K. Weninger, R. Riehn, P. Opresko, H. Wang

Sources: Crossref, ORCID
Added: December 18, 2020

2018 journal article

Cohesin SA2 is a sequence-independent DNA-binding protein that recognizes DNA replication and repair intermediates

Journal of Biological Chemistry, 293(3), 1054–1069.

By: P. Countryman, Y. Fan, A. Gorthi, H. Pan, J. Strickland, P. Kaur, X. Wang, J. Lin ...

Source: NC State University Libraries
Added: August 6, 2018

2018 journal article

Single-molecule DREEM imaging reveals DNA wrapping around human mitochondrial single-stranded DNA binding protein

NUCLEIC ACIDS RESEARCH, 46(21), 11287–11302.

By: P. Kaur, M. Longley, H. Pan, H. Wang & W. Copeland

Sources: NC State University Libraries, ORCID
Added: February 11, 2019

2017 journal article

Cohesin SA2 is a sequence independent DNA binding protein that recognizes DNA replication and repair intermediates

Journal of Biological Chemistry, jbc-M117.

By: P. Countryman, Y. Fan, A. Gorthi, H. Pan, J. Strickland, P. Kaur, X. Wang, J. Lin ...

Source: ORCID
Added: September 23, 2021

2017 journal article

CpG and methylation-dependent DNA binding and dynamics of the methylcytosine binding domain 2 protein at the single-molecule level

Nucleic Acids Research, 45(15), 9164–9177.

By: H. Pan, S. Bilinovich, P. Kaur, R. Riehn, H. Wang & D. Williams

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2017 journal article

Nucleosome-like, Single-stranded DNA (ssDNA)-Histone Octamer Complexes and the Implication for DNA Double Strand Break Repair

Journal of Biological Chemistry, 292(13), 5271–5281.

By: N. Adkins, S. Swygert, P. Kaur, H. Niu, S. Grigoryev, P. Sung, H. Wang, C. Peterson

Source: ORCID
Added: September 23, 2021

2017 journal article

Single Molecule Fluorescence and Atomic Force Microscopy Studies of DNA Repair

Biophysical Journal, 112(3), 7a.

By: D. Erie, K. Bradford, H. Wilkins, J. Bower, Z. Wang, J. Gauer, M. Satusky, R. Qiu ...

Sources: Crossref, ORCID
Added: December 18, 2020

2017 journal article

Using Atomic Force Microscopy to Characterize the Conformational Properties of Proteins and Protein--DNA Complexes That Carry Out DNA Repair

Methods in Enzymology, 592, 187–212.

By: S. LeBlanc, H. Wilkins, Z. Li, P. Kaur, H. Wang & D. Erie

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2017 journal article

Walking the DNA Methylation Tightrope: The Involvement of Intrinsically Disordered Regions of Transcription Factors

Biophysical Journal, 112(3), 207a.

By: S. Bilinovich, H. Pan, P. Kaur, H. Wang & D. Williams

Sources: Crossref, ORCID
Added: December 18, 2020

2016 journal article

Enhanced electrostatic force microscopy reveals higher-order DNA looping mediated by the telomeric protein TRF2

Scientific Reports, 6.

By: P. Kaur, D. Wu, J. Lin, P. Countryman, K. Bradford, D. Erie, R. Riehn, P. Opresko, H. Wang

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA--DNA pairing

Nucleic Acids Research, gkw518.

By: J. Lin, P. Countryman, H. Chen, H. Pan, Y. Fan, Y. Jiang, P. Kaur, W. Miao ...

Source: ORCID
Added: September 23, 2021

2016 journal article

Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA-DNA pairing

Nucleic Acids Research, 44(13), 6363–6376.

By: J. Lin, P. Countryman, H. Chen, H. Pan, Y. Fan, Y. Jiang, P. Kaur, W. Miao ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection

Molecular Cell.

By: D. Benarroch-Popivker, S. Pisano, A. Mendez-Bermudez, L. Lototska, P. Kaur, S. Bauwens, N. Djerbi, C. Latrick ...

Source: ORCID
Added: September 23, 2021

2016 journal article

TRF2-mediated control of telomere DNA topology as a mechanism for chromosome-end protection

Molecular Cell, 61(2), 274–286.

By: D. Benarroch-Popivker, S. Pisano, A. Mendez-Bermudez, L. Lototska, P. Kaur, S. Bauwens, N. Djerbi, C. Latrick ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Visualizing the Path of DNA through Proteins Using DREEM Imaging

Molecular Cell, 61(2), 315–323.

By: D. Wu, P. Kaur, Z. Li, K. Bradford, H. Wang & D. Erie

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2015 journal article

Interference of ATP with the fluorescent probes YOYO-1 and YOYO-3 modifies the mechanical properties of intercalator-stained DNA confined in nanochannels

Microchimica Acta, 182(7-8), 1561–1565.

By: M. Roushan, Z. Azad, S. Lim, H. Wang & R. Riehn

Source: ORCID
Added: September 23, 2021

2015 journal article

Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts

Nature Communications, 6.

By: D. Parikh, E. Fouquerel, C. Murphy, H. Wang & P. Opresko

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Probing transient protein-mediated DNA linkages using nanoconfinement

Biomicrofluidics, 8(3), 034113.

By: M. Roushan, P. Kaur, A. Karpusenko, P. Countryman, C. Ortiz, S. Lim, H. Wang, R. Riehn

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 journal article

Single-molecule analysis reveals human UV-damaged DNA-binding protein (UV-DDB) dimerizes on DNA via multiple kinetic intermediates

Proceedings of the National Academy of Sciences, 111(18), E1862–E1871.

By: H. Ghodke, H. Wang, C. Hsieh, S. Woldemeskel, S. Watkins, V. Rapić-Otrin, B. Van Houten

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2014 conference paper

Single-molecule imaging reveals DNA-binding properties of cohesin proteins SA1 and SA2.

Environmental and Molecular Mutagenesis, 55, S29–29.

By: J. Lin, P. Kaur, H. Chen, P. Countryman, M. Roushan, D. Flaherty, E. Brennan, C. You ...

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres

Nucleic Acids Research, 42(4), 2493–2504.

By: J. Lin, P. Countryman, N. Buncher, P. Kaur, E. Longjiang, Y. Zhang, G. Gibson, C. You ...

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres

Nucleic Acids Research, 42(4), 2493–2504.

By: J. Lin, P. Countryman, N. Buncher, P. Kaur, E. Longjiang, Y. Zhang, G. Gibson, C. You ...

Source: ORCID
Added: September 23, 2021

2014 journal article

Unraveling secrets of telomeres: One molecule at a time

DNA Repair, 20, 142–153.

By: J. Lin, P. Kaur, P. Countryman, P. Opresko & H. Wang

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2013 journal article

DNA polymerase $δ$ stalls on telomeric lagging strand templates independently from G-quadruplex formation

Nucleic Acids Research, 41(22), 10323–10333.

By: J. Lormand, N. Buncher, C. Murphy, P. Kaur, M. Lee, P. Burgers, H. Wang, T. Kunkel, P. Opresko

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2013 review

Investigating bioconjugation by atomic force microscopy

[Review of ]. Journal of Anobiotechnology, 11.

By: I. Tessmer, P. Kaur, J. Lin & H. Wang

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Investigating bioconjugation by atomic force microscopy

J. Nanobiotechnol, 11, 25.

By: I. Tessmer, P. Kaur, J. Lin & H. Wang

Source: ORCID
Added: September 23, 2021

2013 journal article

Real-time single-molecule imaging reveals a direct interaction between UvrC and UvrB on DNA tightropes

Nucleic Acids Research, gkt177.

By: C. Hughes, H. Wang, H. Ghodke, M. Simons, A. Towheed, Y. Peng, B. Van Houten, N. Kad

Source: ORCID
Added: September 23, 2021

2012 journal article

Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair

Proceedings of the National Academy of Sciences, 109(41), E2737–E2746.

By: J. Yeh, A. Levine, S. Du, U. Chinte, H. Ghodke, H. Wang, H. Shi, C. Hsieh ...

Source: ORCID
Added: September 23, 2021

2012 journal article

Werner syndrome protein suppresses the formation of large deletions during the replication of human telomeric sequences

Cell Cycle, 11(16), 3036–3044.

By: R. Damerla, K. Knickelbein, S. Strutt, F. Liu, H. Wang & P. Opresko

Source: ORCID
Added: September 23, 2021

2011 journal article

High accuracy FIONA--AFM hybrid imaging

Ultramicroscopy, 111(5), 350–355.

By: D. Fronczek, C. Quammen, H. Wang, C. Kisker, R. Superfine, R. Taylor, D. Erie, I. Tessmer

Source: ORCID
Added: September 23, 2021

2011 chapter

Nucleotide excision repair from bacteria to humans: Structure--function studies

In Chemical Carcinogenesis (pp. 267–296). Springer.

By: Y. Peng, H. Wang, L. Santana-Santos, C. Kisker & B. Van Houten

Source: ORCID
Added: September 23, 2021

2011 journal article

Single molecule studies of physiologically relevant telomeric tails reveal POT1 mechanism for promoting G-quadruplex unfolding

Journal of Biological Chemistry, 286(9), 7479–7489.

By: H. Wang, G. Nora, H. Ghodke & P. Opresko

Source: ORCID
Added: September 23, 2021

2010 journal article

Collaborative dynamic DNA scanning by nucleotide excision repair proteins investigated by single-molecule imaging of quantum-dot-labeled proteins

Molecular Cell, 37(5), 702–713.

By: N. Kad, H. Wang, G. Kennedy, D. Warshaw & B. Van Houten

Source: ORCID
Added: September 23, 2021

2009 journal article

Replication protein A stimulates the Werner syndrome protein branch migration activity

Journal of Biological Chemistry, 284(50), 34682–34691.

By: G. Sowd, H. Wang, D. Pretto, W. Chazin & P. Opresko

Source: ORCID
Added: September 23, 2021

2009 journal article

The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation

PLoS One, 4(3), e4825.

By: P. Opresko, G. Sowd & H. Wang

Source: ORCID
Added: September 23, 2021

2008 journal article

Efficient processing of TFO-directed psoralen DNA interstrand crosslinks by the UvrABC nuclease

Nucleic Acids Research, 36(22), 7136–7145.

By: L. Christensen, H. Wang, B. Van Houten & K. Vasquez

Source: ORCID
Added: September 23, 2021

2008 journal article

Functional characterization and atomic force microscopy of a DNA repair protein conjugated to a quantum dot

Nano Letters, 8(6), 1631–1637.

By: H. Wang, I. Tessmer, D. Croteau, D. Erie & B. Van Houten

Source: ORCID
Added: September 23, 2021

2007 chapter

Characterization of protein--protein interactions using atomic force microscopy

In Protein Interactions (pp. 39–77). Springer.

By: H. Wang, Y. Yang & D. Erie

Source: ORCID
Added: September 23, 2021

2006 journal article

Structural basis for DNA recognition and processing by UvrB

Nature Structural & Molecular Biology, 13(4), 360–364.

By: J. Truglio, E. Karakas, B. Rhau, H. Wang, M. DellaVecchia, B. Van Houten, C. Kisker

Source: ORCID
Added: September 23, 2021

2006 journal article

The C-terminal zinc finger of UvrA does not bind DNA directly but regulates damage-specific DNA binding

Journal of Biological Chemistry, 281(36), 26370–26381.

By: D. Croteau, M. DellaVecchia, H. Wang, R. Bienstock, M. Melton & B. Van Houten

Source: ORCID
Added: September 23, 2021

2006 journal article

UvrB domain 4, an autoinhibitory gate for regulation of DNA binding and ATPase activity

Journal of Biological Chemistry, 281(22), 15227–15237.

By: H. Wang, M. DellaVecchia, M. Skorvaga, D. Croteau, D. Erie & B. Van Houten

Source: ORCID
Added: September 23, 2021

2005 journal article

Structural insights into the first incision reaction during nucleotide excision repair

The EMBO Journal, 24(5), 885–894.

By: J. Truglio, B. Rhau, D. Croteau, L. Wang, M. Skorvaga, E. Karakas, M. DellaVecchia, H. Wang, B. Van Houten, C. Kisker

Source: ORCID
Added: September 23, 2021

2005 journal article

‘Close-fitting sleeves’: DNA damage recognition by the UvrABC nuclease system

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 577(1), 92–117.

By: B. Van Houten, D. Croteau, M. DellaVecchia, H. Wang & C. Kisker

Source: ORCID
Added: September 23, 2021

2003 journal article

DNA bending and unbending by MutS govern mismatch recognition and specificity

Proceedings of the National Academy of Sciences, 100(25), 14822–14827.

By: H. Wang, Y. Yang, M. Schofield, C. Du, Y. Fridman, S. Lee, E. Larson, J. Drummond ...

Source: ORCID
Added: September 23, 2021

2003 journal article

Functional oligomeric state of avian sarcoma virus integrase

Journal of Biological Chemistry, 278(2), 1323–1327.

By: K. Bao, H. Wang, J. Miller, D. Erie, A. Skalka & I. Wong

Source: ORCID
Added: September 23, 2021

2003 journal article

Quantitative characterization of biomolecular assemblies and interactions using atomic force microscopy

Methods, 29(2), 175–187.

By: Y. Yang, H. Wang & D. Erie

Source: ORCID
Added: September 23, 2021

2002 journal article

A minimal exonuclease domain of WRN forms a hexamer on DNA and possesses both 3'-5'exonuclease and 5'-protruding strand endonuclease activities

Biochemistry, 41(9), 2901–2912.

By: Y. Xue, G. Ratcliff, H. Wang, P. Davis-Searles, M. Gray, D. Erie, M. Redinbo

Source: ORCID
Added: September 23, 2021

2002 journal article

DNA binding properties of the yeast Msh2-Msh6 and Mlh1-Pms1 heterodimers

Biological Chemistry, 383(6), 969–975.

By: K. Drotschmann, M. Hall, P. Shcherbakova, H. Wang, D. Erie, F. Brownewell, E. Kool, T. Kunkel

Source: ORCID
Added: September 23, 2021

2001 journal article

High affinity cooperative DNA binding by the yeast Mlh1-Pms1 heterodimer

Journal of Molecular Biology, 312(4), 637–647.

By: M. Hall, H. Wang, D. Erie & T. Kunkel

Source: ORCID
Added: September 23, 2021