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Liu, M., Pan, H., Kaur, P., Wang, L. J., Jin, M., Detwiler, A. C., … Riehn, R. (2023). Assembly path dependence of telomeric DNA compaction by TRF1, TIN2, and SA1. BIOPHYSICAL JOURNAL, 122(10), 1822–1832. https://doi.org/10.1016/j.bpj.2023.04.014

Kaur, P., Lu, X., Xu, Q., Irvin, E. M., Pappas, C., Zhang, H., … Wang, H. (2023). High-speed AFM imaging reveals DNA capture and loop extrusion dynamics by cohesin-NIPBL. JOURNAL OF BIOLOGICAL CHEMISTRY, 299(11). https://doi.org/10.1016/j.jbc.2023.105296

Laspata, N., Kaur, P., Mersaoui, S. Y., Muoio, D., Liu, Z. S., Bannister, M. H., … Fouquerel, E. (2023, February 16). PARP1 associates with R-loops to promote their resolution and genome stability. NUCLEIC ACIDS RESEARCH, Vol. 2. https://doi.org/10.1093/nar/gkad066

Irvin, E. M., & Wang, H. (2023). Single-molecule imaging of genome maintenance proteins encountering specific DNA sequences and structures. DNA REPAIR, 128. https://doi.org/10.1016/j.dnarep.2023.103528

Wojtaszek, J. L., Hoff, K. E., Longley, M. J., Kaur, P., Andres, S. N., Wang, H., … Copeland, W. C. (2023, August 18). Structure-specific roles for PolG2-DNA complexes in maintenance and replication of mitochondrial DNA. NUCLEIC ACIDS RESEARCH, Vol. 8. https://doi.org/10.1093/nar/gkad679

Leighton, G. O., Irvin, E. M., Kaur, P., Liu, M., You, C., Bhattaram, D., … Williams Jr, D. C. (2022). Densely methylated DNA traps Methyl-CpG-binding domain protein 2 but permits free diffusion by Methyl-CpG-binding domain protein 3. JOURNAL OF BIOLOGICAL CHEMISTRY, 298(10). https://doi.org/10.1016/j.jbc.2022.102428

Li, Z., Kaur, P., Lo, C.-Y., Chopra, N., Smith, J., Wang, H., & Gao, Y. (2022, November 18). Structural and dynamic basis of DNA capture and translocation by mitochondrial Twinkle helicase. NUCLEIC ACIDS RESEARCH, Vol. 11. https://doi.org/10.1093/nar/gkac1089

Pan, H., Kaur, P., Barnes, R., Detwiler, A. C., Sanford, S. L., Liu, M., … Wang, H. (2021). Structure, dynamics, and regulation of TRF1-TIN2-mediated trans- and cis-interactions on telomeric DNA. JOURNAL OF BIOLOGICAL CHEMISTRY, 297(3). https://doi.org/10.1016/j.jbc.2021.101080

Pan, H., Kaur, P., Barnes, R., Detwiler, A. C., Sanford, S. L., Liu, M., … others. (2021). Structure, dynamics, and regulation of TRF1-TIN2-mediated trans-and cis-interactions on telomeric DNA. Journal of Biological Chemistry, 101080.

Kaur, P., Barnes, R., Pan, H., Detwiler, A. C., Liu, M., Mahn, C., … Wang, H. (2021). TIN2 is an architectural protein that facilitates TRF2-mediated trans- and cis-interactions on telomeric DNA. NUCLEIC ACIDS RESEARCH, 49(22), 13000–13018. https://doi.org/10.1093/nar/gkab1142

Kaur, P., Pan, H., Longley, M. J., Copeland, W. C., & Wang, H. (2021). Using Atomic Force Microscopy to Study the Real Time Dynamics of DNA Unwinding by Mitochondrial Twinkle Helicase. BIO-PROTOCOL, 11(17). https://doi.org/10.21769/BioProtoc.4139

Pan, H., Jin, M., Ghadiyaram, A., Kaur, P., Miller, H. E., Ta, H. M., … Wang, H. (2020). Cohesin SA1 and SA2 are RNA binding proteins that localize to RNA containing regions on DNA. NUCLEIC ACIDS RESEARCH, 48(10), 5639–5655. https://doi.org/10.1093/nar/gkaa284

Pan, H., Jin, M., Ghadiyaram, A., Kaur, P., Miller, H. E., Ta, H. M., … others. (2020). Cohesin SA1 and SA2 are RNA binding proteins that localize to RNA containing regions on DNA. Nucleic Acids Research.

Liu, M., Movahed, S., Dangi, S., Pan, H., Kaur, P., Bilinovich, S. M., … Riehn, R. (2020). DNA looping by two 5-methylcytosine-binding proteins quantified using nanofluidic devices. EPIGENETICS & CHROMATIN, 13(1). https://doi.org/10.1186/s13072-020-00339-7

Kaur, P., Longley, M. J., Pan, H., Wang, W., Countryman, P., Wang, H., & Copeland, W. C. (2020). Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase. JOURNAL OF BIOLOGICAL CHEMISTRY, 295(17), 5564–5576. https://doi.org/10.1074/jbc.RA120.012795

Kaur, P., Longley, M. J., Pan, H., Wang, W., Countryman, P., Wang, H., & Copeland, W. C. (2020). Single-molecule level structural dynamics of DNA unwinding by human mitochondrial Twinkle helicase. Journal of Biological Chemistry, 295(17), 5564–5576.

Wang, H., Ghadiyaram, A., Pan, H., Fan, Y., Kaur, P., Gorthi, A., … Jane Tao, Y. (2019). Cohesin SA2 and EWSR1 in R-Loop Regulation. Biophysical Journal, 116(3), 505a. https://doi.org/10.1016/J.BPJ.2018.11.2723

Fouquerel, E., Barnes, R. P., Wang, H., & Opresko, P. L. (2019). Measuring UV Photoproduct Repair in Isolated Telomeres and Bulk Genomic DNA. DNA REPAIR: METHODS AND PROTOCOLS, Vol. 1999, pp. 295–306. https://doi.org/10.1007/978-1-4939-9500-4_20

Fouquerel, E., Barnes, R. P., Wang, H., & Opresko, P. L. (2019). Measuring UV Photoproduct Repair in Isolated Telomeres and Bulk Genomic DNA. In DNA Repair (pp. 295–306). Springer.

Kaur, P., Barnes, R., Pan, H., Opresko, P., Riehn, R., & Wang, H. (2019). Single-Molecule Study of TRF2 Mediated DNA Compaction using Physiologically Relevant Long Telomeric DNA. Biophysical Journal, 116(3), 505a. https://doi.org/10.1016/J.BPJ.2018.11.2725

Pan, H., Dangi, S., Kaur, P., Hao, P., Weninger, K., Riehn, R., … Wang, H. (2019). TIN2 is an Architectural Protein Stabilizing TRF1 at Telomere. Biophysical Journal, 116(3), 211a–212a. https://doi.org/10.1016/J.BPJ.2018.11.1168

Countryman, P., Fan, Y., Gorthi, A., Pan, H., Strickland, J., Kaur, P., … Wang, H. (2018). Cohesin SA2 is a sequence-independent DNA-binding protein that recognizes DNA replication and repair intermediates. JOURNAL OF BIOLOGICAL CHEMISTRY, 293(3), 1054–1069. https://doi.org/10.1074/jbc.m117.806406

Kaur, P., Longley, M. J., Pan, H., Wang, H., & Copeland, W. C. (2018). Single-molecule DREEM imaging reveals DNA wrapping around human mitochondrial single-stranded DNA binding protein. NUCLEIC ACIDS RESEARCH, 46(21), 11287–11302. https://doi.org/10.1093/nar/gky875

Countryman, P., Fan, Y., Gorthi, A., Pan, H., Strickland, J., Kaur, P., … others. (2017). Cohesin SA2 is a sequence independent DNA binding protein that recognizes DNA replication and repair intermediates. Journal of Biological Chemistry, jbc-M117.

Pan, H., Bilinovich, S. M., Kaur, P., Riehn, R., Wang, H., & Williams, D. C., Jr. (2017). CpG and methylation-dependent DNA binding and dynamics of the methylcytosine binding domain 2 protein at the single-molecule level. NUCLEIC ACIDS RESEARCH, 45(15), 9164–9177. https://doi.org/10.1093/nar/gkx548

Adkins, N. L., Swygert, S. G., Kaur, P., Niu, H., Grigoryev, S. A., Sung, P., … Peterson, C. L. (2017). Nucleosome-like, Single-stranded DNA (ssDNA)-Histone Octamer Complexes and the Implication for DNA Double Strand Break Repair. Journal of Biological Chemistry, 292(13), 5271–5281.

Erie, D., Bradford, K., Wilkins, H., Bower, J., Wang, Z., Gauer, J., … Wang, H. (2017). Single Molecule Fluorescence and Atomic Force Microscopy Studies of DNA Repair. Biophysical Journal, 112(3), 7a. https://doi.org/10.1016/J.BPJ.2016.11.061

LeBlanc, S., Wilkins, H., Li, Z., Kaur, P., Wang, H., & Erie, D. A. (2017). Using Atomic Force Microscopy to Characterize the Conformational Properties of Proteins and Protein--DNA Complexes That Carry Out DNA Repair. Methods in Enzymology, 592, 187–212.

Bilinovich, S. M., Pan, H., Kaur, P., Wang, H., & Williams, D. C., Jr. (2017). Walking the DNA Methylation Tightrope: The Involvement of Intrinsically Disordered Regions of Transcription Factors. Biophysical Journal, 112(3), 207a. https://doi.org/10.1016/J.BPJ.2016.11.1144

Kaur, P., Wu, D., Lin, J., Countryman, P., Bradford, K. C., Erie, D. A., … Wang, H. (2016). Enhanced electrostatic force microscopy reveals higher-order DNA looping mediated by the telomeric protein TRF2. Scientific Reports, 6(1). https://doi.org/10.1038/SREP20513

Lin, J., Countryman, P., Chen, H., Pan, H., Fan, Y., Jiang, Y., … others. (2016). Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA--DNA pairing. Nucleic Acids Research, gkw518.

Lin, J., Countryman, P., Chen, H., Pan, H., Fan, Y., Jiang, Y., … Wang, H. (2016). Functional interplay between SA1 and TRF1 in telomeric DNA binding and DNA-DNA pairing. NUCLEIC ACIDS RESEARCH, 44(13), 6363–6376. https://doi.org/10.1093/nar/gkw518

Benarroch-Popivker, D., Pisano, S., Mendez-Bermudez, A., Lototska, L., Kaur, P., Bauwens, S., … others. (2016). TRF2-Mediated Control of Telomere DNA Topology as a Mechanism for Chromosome-End Protection. Molecular Cell.

Benarroch-Popivker, D., Pisano, S., Mendez-Bermudez, A., Lototska, L., Kaur, P., Bauwens, S., … Ye, J. (2016). TRF2-mediated control of telomere DNA topology as a mechanism for chromosome-end protection. Molecular Cell, 61(2), 274–286.

Wu, D., Kaur, P., Li, Z. M., Bradford, K. C., Wang, H., & Erie, D. A. (2016). Visualizing the Path of DNA through Proteins Using DREEM Imaging. MOLECULAR CELL, 61(2), 315–323. https://doi.org/10.1016/j.molcel.2015.12.012

Countryman, P. J., Lin, J., Kaur, P., Brennan, E., Chen, H., You, C., … Wang, H. (2015). Determining the DNA Diffusion Behavior of SA2 on Various DNA Substrates. Biophysical Journal, 108(2), 397a. https://doi.org/10.1016/J.BPJ.2014.11.2177

Roushan, M., Azad, Z., Lim, S. F., Wang, H., & Riehn, R. (2015). Interference of ATP with the fluorescent probes YOYO-1 and YOYO-3 modifies the mechanical properties of intercalator-stained DNA confined in nanochannels. Microchimica Acta, 182(7-8), 1561–1565. https://doi.org/10.1007/S00604-015-1495-7

Wang, H., Lin, J., Kaur, P., Countryman, P., Opresko, P., Smith, S., & Tao, J. (2015). Revealing Structure and Dynamics of Telomere Maintenance Proteins on DNA: One Molecule at a Time. Biophysical Journal, 108(2), 7a. https://doi.org/10.1016/J.BPJ.2014.11.059

Lin, J., Chen, H., Kaur, P., Miao, W., Countryman, P., You, C., … Wang, H. (2015). Single-Molecule Imaging Reveals Dynamics of SA1-TRF1 Interactions on Telomeric DNA. Biophysical Journal, 108(2), 206a. https://doi.org/10.1016/J.BPJ.2014.11.1138

Parikh, D., Fouquerel, E., Murphy, C. T., Wang, H., & Opresko, P. L. (2015). Telomeres are partly shielded from ultraviolet-induced damage and proficient for nucleotide excision repair of photoproducts. NATURE COMMUNICATIONS, 6. https://doi.org/10.1038/ncomms9214

Roushan, M., Kaur, P., Karpusenko, A., Countryman, P. J., Ortiz, C. P., Fang Lim, S., … Riehn, R. (2014). Probing transient protein-mediated DNA linkages using nanoconfinement. Biomicrofluidics, 8(3), 034113. https://doi.org/10.1063/1.4882775

Ghodke, H., Wang, H., Hsieh, C. L., Woldemeskel, S., Watkins, S. C., Rapic-Otrin, V., & Van Houten, B. (2014). Single-molecule analysis reveals human UV-damaged DNA-binding protein (UV-DDB) dimerizes on DNA via multiple kinetic intermediates. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 111(18), E1862–E1871. https://doi.org/10.1073/pnas.1323856111

Lin, J., Kaur, P., Chen, H., Countryman, P., Roushan, M., Flaherty, D., … Wang, H. (2014). Single-molecule imaging reveals DNA-binding properties of cohesin proteins SA1 and SA2. Environmental and Molecular Mutagenesis, 55, S29–29.

Lin, J., Countryman, P., Buncher, N., Kaur, P., Longjiang, E., Zhang, Y., … Wang, H. (2014). TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres. NUCLEIC ACIDS RESEARCH, 42(4), 2493–2504. https://doi.org/10.1093/nar/gkt1132

Lin, J., Countryman, P., Buncher, N., Kaur, P., Longjiang, E., Zhang, Y., … others. (2014). TRF1 and TRF2 use different mechanisms to find telomeric DNA but share a novel mechanism to search for protein partners at telomeres. Nucleic Acids Research, 42(4), 2493–2504.

Lin, J., Kaur, P., Countryman, P., Opresko, P. L., & Wang, H. (2014). Unraveling secrets of telomeres: One molecule at a time. DNA REPAIR, 20, 142–153. https://doi.org/10.1016/j.dnarep.2014.01.012

Lormand, J. D., Buncher, N., Murphy, C. T., Kaur, P., Lee, M. Y., Burgers, P., … Opresko, P. L. (2013). DNA polymerase delta stalls on telomeric lagging strand templates independently from G-quadruplex formation. NUCLEIC ACIDS RESEARCH, 41(22), 10323–10333. https://doi.org/10.1093/nar/gkt813

Tessmer, I., Kaur, P., Lin, J. G., & Wang, H. (2013). [Review of Investigating bioconjugation by atomic force microscopy]. Journal of Anobiotechnology, 11.

Tessmer, I., Kaur, P., Lin, J., & Wang, H. (2013). Investigating bioconjugation by atomic force microscopy. J. Nanobiotechnol, 11, 25.

Hughes, C. D., Wang, H., Ghodke, H., Simons, M., Towheed, A., Peng, Y., … Kad, N. M. (2013). Real-time single-molecule imaging reveals a direct interaction between UvrC and UvrB on DNA tightropes. Nucleic Acids Research, gkt177.

Ghodke, H., Wang, H., Hsieh, C. L., Gibson, G., Watkins, S., Rapic-Otrin, V., … Van Houten, B. (2013). WT UV-DDB Performs a 3D Search on DNA whereas the XP-E Mutant (K244E DDB2) Mutant Slides. Biophysical Journal, 104(2), 77a. https://doi.org/10.1016/j.bpj.2012.11.462

Hughes, C. D., Towheed, M. A., Simons, M., Wang, H., Van Houten, B., & Kad, N. M. (2012). A New Role for UvrB in NER? Single Molecule Imaging of the NER Complex UvrBC-DNA. Biophysical Journal, 102(3), 485a. https://doi.org/10.1016/j.bpj.2011.11.2659

Yeh, J. I., Levine, A. S., Du, S., Chinte, U., Ghodke, H., Wang, H., … Rapic-Otrin, V. (2012). Damaged DNA induced UV-damaged DNA-binding protein (UV-DDB) dimerization and its roles in chromatinized DNA repair. Proceedings of the National Academy of Sciences, 109(41), E2737–E2746. https://doi.org/10.1073/pnas.1110067109

Damerla, R. R., Knickelbein, K. E., Strutt, S., Liu, F.-J., Wang, H., & Opresko, P. L. (2012). Werner syndrome protein suppresses the formation of large deletions during the replication of human telomeric sequences. Cell Cycle, 11(16), 3036–3044.

Fronczek, D. N., Quammen, C., Wang, H., Kisker, C., Superfine, R., Taylor, R., … Tessmer, I. (2011). High accuracy FIONA–AFM hybrid imaging. Ultramicroscopy, 111(5), 350–355. https://doi.org/10.1016/j.ultramic.2011.01.020

Keller, R., Wang, H., Towheed, M. A., Van Houten, B., & Kad, N. M. (2011). Investigating Nucleotide Excision DNA Repair by Single-Molecule Imaging of Quantum Dot Labeled Proteins Reveals Unique Scanning Mechanisms. Biophysical Journal, 100(3), 240a. https://doi.org/10.1016/j.bpj.2010.12.1531

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Wang, H., Nora, G. J., Ghodke, H., & Opresko, P. L. (2011). Single Molecule Studies of Physiologically Relevant Telomeric Tails Reveal POT1 Mechanism for Promoting G-quadruplex Unfolding. Journal of Biological Chemistry, 286(9), 7479–7489. https://doi.org/10.1074/jbc.M110.205641

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Sowd, G., Wang, H., Pretto, D., Chazin, W. J., & Opresko, P. L. (2009). Replication Protein A Stimulates the Werner Syndrome Protein Branch Migration Activity. Journal of Biological Chemistry, 284(50), 34682–34691. https://doi.org/10.1074/jbc.M109.049031

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