Hann Wen Tam

Works (2)

Updated: July 5th, 2023 15:40

2019 article

C/EBPβ suppresses keratinocyte autonomous type 1 IFN response and p53 to increase cell survival and susceptibility to UVB-induced skin cancer

Tam, H. W., Hall, J. R., Messenger, Z. J., Jima, D. D., House, J. S., Linder, K., & Smart, R. C. (2019, January 23). Carcinogenesis, Vol. 40, pp. 1099–1109.

By: H. Tam n, J. Hall n , Z. Messenger n, D. Jima n, J. House n , K. Linder n, R. Smart n 

Contributors: H. Tam n, J. Hall n , Z. Messenger n, D. Jima n, J. House n , K. Linder n, R. Smart n 

topics (OpenAlex): interferon and immune responses; Skin Protection and Aging
TL;DR: A p53-C/E BPβ feedback loop, whereby C/EBPβ a transcriptional target of a p53 pathway, functions as a survival factor by negatively regulating p53 apoptotic activity in response to DNA damage is suggested. (via Semantic Scholar)
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: November 18, 2019

2015 article

Long noncoding RNA lincRNA-p21 is the major mediator of UVB-induced and p53-dependent apoptosis in keratinocytes

Hall, J. R., Messenger, Z. J., Tam, H. W., Phillips, S. L., Recio, L., & Smart, R. C. (2015, March 19). Cell Death and Disease, Vol. 6.

By: J. Hall n , Z. Messenger n, H. Tam n, S. Phillips*, L. Recio * & R. Smart n 

MeSH headings : Animals; Apoptosis / genetics; Apoptosis / radiation effects; Cell Cycle Checkpoints / genetics; Cell Cycle Checkpoints / radiation effects; Cell Line; Cell Proliferation / genetics; Cell Proliferation / radiation effects; DNA Damage / genetics; DNA Damage / radiation effects; Gene Expression Regulation / radiation effects; Humans; Keratinocytes / metabolism; Keratinocytes / pathology; Keratinocytes / radiation effects; Mice; RNA, Long Noncoding / biosynthesis; RNA, Long Noncoding / genetics; Skin / metabolism; Skin / pathology; Skin / radiation effects; Skin Neoplasms / genetics; Skin Neoplasms / pathology; Tumor Suppressor Protein p53 / genetics; Ultraviolet Rays
topics (OpenAlex): Cancer-related molecular mechanisms research
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UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

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