Works (36)

Updated: September 27th, 2024 05:00

2024 article

Carbon nanofibers/liquid metal composites for high temperature laser ultrasound

Garcia, N., Kim, H., Vinod, K., Sahoo, A., Wax, M., Kim, T., … Jiang, X. (2024, March). ULTRASONICS, Vol. 138.

author keywords: Photoacoustic; Carbon nanofiber; High temperature; Laser ultrasound; Liquid metal
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 26, 2024

2024 journal article

Electrical de-poling and re-poling of relaxor-PbTiO<sub>3</sub> piezoelectric single crystals without heat treatment

NATURE COMMUNICATIONS, 15(1).

By: H. Kim n, M. Zhang*, B. Wang*, H. Wu n, Z. Xu n, S. Liu n, S. Moon n, Y. Yamashita* ...

Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 1, 2024

2024 journal article

Electro-elastic characteristics of KCsMoP2O9 crystal: Exploiting strong piezoelectricity for guided wave transducer applications

JOURNAL OF MATERIOMICS, 11(1).

author keywords: Christoffel equation; Electro-elastic properties; Shear horizontal wave transducer; Damage detection
Source: Web Of Science
Added: September 9, 2024

2024 journal article

High-Performance PMN-PT Single-Crystal-Based 1-3 Composite Transducer Integrated with a Biopsy Needle

BIOSENSORS-BASEL, 14(2).

By: B. Kreager n, H. Wu n, W. Chang, S. Moon n, J. Mitchell n, C. Peng*, C. Huang*, M. Muller n, J. Tian, X. Jiang n

author keywords: imaging-guided biopsy; high-frequency ultrasound; piezoelectric; fine needle aspiration; ultrasound imaging
TL;DR: The integrated biopsy needle prototype exhibited high accuracy in estimating nodule area compared to actual dimensions in vitro and underscores the promising potential of biopsy-needle-integrated transducers in enhancing the accuracy of endoscopic ultrasound-guided fine needle aspiration biopsy (EUS-FNA) for clinical applications. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: March 11, 2024

2024 journal article

Ultrasound-Compatible Electrode for Functional Electrical Stimulation

BIOMEDICINES, 12(8).

By: S. Moon n, X. Xue n, V. Ganesh n, D. Shukla n, B. Kreager n, Q. Cai n, H. Wu n, Y. Zhu n, N. Sharma n, X. Jiang n

author keywords: body-conforming ultrasound-compatible electrode; functional electrical stimulation (FES); silver nanowire (AgNW) electrode; ultrasound (US); wearable ultrasound
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 8, 2024

2023 journal article

A Model of High-Speed Endovascular Sonothrombolysis with Vortex Ultrasound-Induced Shear Stress to Treat Cerebral Venous Sinus Thrombosis

RESEARCH, 6, 1–13.

By: B. Zhang n, H. Wu n, H. Kim n, P. Welch*, A. Cornett*, G. Stocker*, R. Nogueira*, J. Kim* ...

Contributors: B. Zhang n, H. Wu n, H. Kim n, P. Welch*, A. Cornett*, G. Stocker*, R. Nogueira*, J. Kim* ...

Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 5, 2023

2023 journal article

Flexible Ultrasonic Transducers for Wearable Biomedical Applications: A Review on Advanced Materials, Structural Designs, and Future Prospects

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 71(7), 786–810.

By: X. Xue n, H. Wu n, Q. Cai n, M. Chen n, S. Moon n, Z. Huang*, T. Kim*, C. Peng* ...

author keywords: Transducers; Ultrasonic imaging; Biomedical imaging; Sensors; Acoustics; Piezoelectric materials; Biomedical monitoring; biomedical sensing; biomedical therapy; flexible electronics; flexible ultrasound; ultrasound transducers
TL;DR: This article comprehensively reviews the application of flexible ultrasound transducers in the field of biomedical imaging, sensing, and therapy and highlights some promising preliminary data with recent applications. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: January 28, 2024

2023 journal article

Intravascular Sono-Ablation for In-Stent Restenosis Relief: Transducer Development and the In-Vitro Demonstration

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 70(7), 2172–2180.

By: H. Kim n, H. Wu n, M. Chen n, X. Dai, R. Zhou* & X. Jiang n

author keywords: In stent restenosis; focused ultrasound; tissue ablation; interstitial transducer; small aperture
MeSH headings : Humans; Coronary Restenosis; Stents; Computer Simulation; Treatment Outcome
TL;DR: The developed device can be used for sonoablation of the remaining plaque, providing a novel approach to the treatment of ISR, suggesting it could be as a future ISR treatment modality. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 7, 2023

2023 article

Intravascular sonothrombolysis with nanobubbles : <i>in</i>-<i>vitro</i> study

2023 IEEE 23RD INTERNATIONAL CONFERENCE ON NANOTECHNOLOGY, NANO, pp. 376–379.

Contributors: H. Wu n, B. Kreager n, M. Chen n, B. Zhang n, E. Abenojar*, A. Exner*, X. Jiang n

author keywords: Micro/Nano-bubble mixture; Sonothrombolysis
TL;DR: An innovative method utilizing a stacked transducer for intravascular sonothrombolysis for higher lysis efficiency, employing a mixture of nanobubbles (NB) and microbubbles (MB) serves to enhance cavitation and improve the breakdown of clot structures. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 23, 2023

2023 article

Lung nodule biopsy guided using a 30 MHz ultrasound transducer: in vitro study

HEALTH MONITORING OF STRUCTURAL AND BIOLOGICAL SYSTEMS XVII, Vol. 12488.

By: B. Kreager n, S. Moon n, J. Mitchell n, H. Wu n, C. Peng*, M. Muller n, C. Huang*, X. Jiang n

author keywords: High-frequency ultrasound; piezoelectric; ultrasound imaging; fine needle aspiration; imaging guided biopsy; lung nodule
TL;DR: Results showed that the 30 MHz ultrasound transducer can map the geometry of the gelatin-foam boundary, indicating the capability of distinguishing tumor and healthy lung tissue with this ultrasound-guided biopsy technique. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: July 31, 2023

2023 journal article

Miniaturized Stacked Transducer for Intravascular Sonothrombolysis With Internal-Illumination Photoacoustic Imaging Guidance and Clot Characterization

IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 70(8), 2279–2288.

By: H. Wu n, Y. Tang*, B. Zhang n, P. Klippel*, Y. Jing*, J. Yao*, X. Jiang n

Contributors: H. Wu n, Y. Tang*, B. Zhang n, P. Klippel*, Y. Jing*, J. Yao*, X. Jiang n

author keywords: Intravascular ultrasound transducer; sonothrombolysis; deep tissue imaging; functional imaging; photoacoustic imaging; internal illumination
TL;DR: The findings have demonstrated the feasibility of the proposed PAT-guided intravascular sonothrombolysis with real-time feedback during the treatment process and the treatment efficiency for clinical application may not be optimized. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 1, 2023

2023 article

Nanotechnology-Enabled Ultrasound Transducers

Peng, C., Wu, H., & Jiang, X. (2023, August 2). IEEE NANOTECHNOLOGY MAGAZINE.

By: C. Peng*, H. Wu n & X. Jiang n

author keywords: Transducers; Ultrasonic imaging; Nanomaterials; Acoustics; Nanoparticles; Zinc oxide; Polymers; Flexible ultrasound transducer; laser ultrasound transducer; nanofabrication; nanomaterials; nanotechnology; ultrasound transducer
TL;DR: The objective of this review is to provide the state-of-the-art advancement of nanotechnology-enabled ultrasound transducers, with a focus on nanomaterials applied in both piezoelectric transducers and optoacoustictransducers, as well as fabrication techniques of nanostructured materials for ultrasoundtransducers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 21, 2023

2023 journal article

Vortex-ultrasound for microbubble-mediated thrombolysis of retracted clots

APPLIED PHYSICS LETTERS, 123(7).

Contributors: H. Kim n, B. Zhang n, H. Wu n, J. Yao*, C. Shi* & X. Jiang n

TL;DR: The use of endovascular vortex ultrasound holds promise as a potential clinical option for the thrombolysis of retracted clots due to its potential to induce shear stress and enhance the clot lysis. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: September 5, 2023

2022 article

A Dual-Frequency Intravascular Ultrasound Transducer for Amplified Nanodroplet Vaporization Effects in Cavitation-Enhanced Sonothrombolysis

2022 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS).

By: S. Moon n, H. Wu n, B. Zhang n, J. Kim*, P. Dayton*, Z. Xu*, X. Jiang n

author keywords: Intravascular transducer; dual-frequency thrombolysis; Nanodroplets
TL;DR: A dual-frequency intravascular transducer intended for nanodroplet-specific sonothrombolysis was developed to improve clot mass reduction rate while retaining lower acoustic pressures than the typical nanODroplet vaporization threshold at sub-megahertz excitation (> 5 MPa). (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: February 6, 2023

2022 article

A Laser-Coupled Dual Excitation Intravascular Ultrasound Transducer for Sonothrombolysis

2022 IEEE NANOTECHNOLOGY MATERIALS AND DEVICES CONFERENCE, NMDC, pp. 37–40.

By: B. Zhang n, H. Wu n & X. Jiang n

Contributors: B. Zhang n, H. Wu n & X. Jiang n

author keywords: laser ultrasound; carbon nanoparticles; ultrasound transducer; sonothrombolysis; catheter ultrasound
TL;DR: In this paper, a miniaturized dual excitation laser-coupled intravascular ultrasound transducer with both a piezoelectric stack and a laser ultrasoundTransducer, which can generate a low-frequency and high-frequencyDual excitation waves for thrombolysis is introduced. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 30, 2023

2022 article

A multi-directional transducer array for muscle shear wave anisotropy estimation

2022 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS).

By: H. Wu n, B. Zhang n, G. Xu*, C. Huang* & X. Jiang n

author keywords: Multi-direction array; shear wave ultrasound imaging
TL;DR: A novel star-shape transducer array designed and fabricated in order to measure SWV for exploring the anisotropic properties of muscles showed a great potential in assessment of tissue anisotropy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: February 6, 2023

2022 article

Deep thrombosis characterization using photoacoustic imaging with intravascular light delivery

Tang, Y., Wu, H., Klippel, P., Zhang, B., Huang, H.-Y. S., Jing, Y., … Yao, J. (2022, February 16). BIOMEDICAL ENGINEERING LETTERS, Vol. 12.

By: Y. Tang*, H. Wu n, P. Klippel*, B. Zhang n, H. Huang n, Y. Jing*, X. Jiang n, J. Yao*

Contributors: Y. Tang*, H. Wu n, P. Klippel*, B. Zhang n, H. Huang n, Y. Jing*, X. Jiang n, J. Yao*

author keywords: Thrombosis; Photoacoustic tomography; Internal light illumination; Photoacoustic frequency; Retracted blood clot; Unretracted blood clot; Blood oxygenation
TL;DR: The results show that, with intravascular light delivery, clot oxygenation level can be accurately measured, and the clot age can thus be estimated, and it is found that retracted and unretracted clots had different acoustic frequency spectrum. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 7, 2022

2022 article

Integration of Forward-viewing and Side-viewing Ultrasound Transducers in an Intravascular Sonothrombolysis Catheter

2022 IEEE INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS).

By: B. Zhang n, H. Wu n, J. Kim*, P. Dayton*, Z. Xu* & X. Jiang n

author keywords: ultrasound transducers; microbubbles; thrombus; thrombolysis; sonothrombolysis
TL;DR: The combination of forward and side-viewing (FSV) ultrasound waves is expected to extend the treatment region and improve thrombolysis efficiency compared to a forward or side-Viewing alone sonication. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: February 6, 2023

2022 article

Numerical and experimental evaluation of low-intensity transcranial focused ultrasound wave propagation using human skulls for brain neuromodulation

Chen, M., Peng, C., Wu, H., Huang, C.-C., Kim, T., Traylor, Z., … Jiang, X. (2022, November 24). MEDICAL PHYSICS, Vol. 11.

By: M. Chen n, C. Peng n, H. Wu n, C. Huang n, T. Kim*, Z. Traylor n, M. Muller n, P. Chhatbar* ...

author keywords: human skull; transcranial focused ultrasound; ultrasonic neuromodulation; ultrasound transducer
MeSH headings : Humans; Skull / diagnostic imaging; Brain / diagnostic imaging; Ultrasonography / methods; Head; Transducers; Ultrasonic Waves
TL;DR: The findings have important implications to predict tFUS wave propagation for ultrasound neuromodulation in clinical applications, and guide researchers to develop advanced ultrasound transducers as neural interfaces. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: December 12, 2022

2022 article

Ultrasound and magnetic dual-mode stacked transducer for sonothrombolysis with a combination of nanodroplets and magnetic nanoparticles

2022 IEEE 22ND INTERNATIONAL CONFERENCE ON NANOTECHNOLOGY (NANO), pp. 71–74.

By: B. Zhang n, H. Wu n & X. Jiang n

Contributors: B. Zhang n, H. Wu n & X. Jiang n

TL;DR: A 4-element stacked transducer with a center frequency of 450 kHz, which can create ultrasonic waves in addition to a high frequency oscillating magnetic field to activate the superparamagnetic iron oxide nanoparticles (SPIONs) and nanodroplets is demonstrated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: December 12, 2022

2022 journal article

Ultrasound-Guided Intravascular Sonothrombolysis With a Dual Mode Ultrasound Catheter: In Vitro Study

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 69(6), 1917–1925.

Contributors: H. Wu n, B. Zhang n, C. Huang*, C. Peng*, Q. Zhou* & X. Jiang n

author keywords: Imaging-guided sonothombolysis; intravascular ultrasound transducer; ultrasound imaging
MeSH headings : Animals; Catheters; Cattle; Thromboembolism; Thrombosis / therapy; Transducers; Ultrasonography / methods; Ultrasonography, Interventional
TL;DR: The findings suggest that the proposed ultrasound-guided intravascular sonothrombolysis can be enhanced since the position of treatment transducer can be adjusted with the target at the clot due to the imaging guide. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 13, 2022

2021 journal article

A multi-pillar piezoelectric stack transducer for nanodroplet mediated intravascular sonothrombolysis

ULTRASONICS, 116.

By: H. Kim n, J. Kim n, H. Wu n, B. Zhang n, P. Dayton n & X. Jiang n

Contributors: H. Kim n, J. Kim n, H. Wu n, B. Zhang n, P. Dayton n & X. Jiang n

author keywords: Intravascular transducer; Sonothrombolysis; Nanodroplet; Piezoelectric stack; Small aperture
TL;DR: The ND-mediated intravascular sonothrombolysis using MPPS transducers was demonstrated with an unprecedented lysis rate, which may offer a new clinical option for DVT treatments. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 16, 2021

2021 journal article

Dual-Frequency Intravascular Sonothrombolysis: An In Vitro Study

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 68(12), 3599–3607.

By: H. Wu n, L. Goel n, H. Kim n, B. Zhang n, J. Kim*, P. Dayton*, Z. Xu*, X. Jiang n

Contributors: H. Wu n, L. Goel n, H. Kim n, B. Zhang n, J. Kim*, P. Dayton*, Z. Xu*, X. Jiang n

author keywords: Transducers; Acoustics; Ultrasonic imaging; Frequency measurement; Frequency control; Impedance; Broadband communication; Dual-frequency thrombolysis; intravascular ultrasound transducer; passive cavitation; sonothrombolysis
MeSH headings : Acoustics; Contrast Media; Microbubbles; Transducers; Ultrasonic Therapy
TL;DR: A new broadband intravascular transducer is developed and tests indicated that the MB-mediated, dual-frequency (750+500 kHz) sonothrombolysis yields an 85% higher lysis rate compared with the single-frequency treatment, and the lysis Rate increases with the difference between the two frequency components. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 24, 2021

2021 article

Intravascular Dual-frequency Ultrasound Transducer Using a Stack Composite

INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS 2021).

By: H. Wu n, H. Kim n, B. Zhang n, J. Kim*, P. Dayton*, Z. Xu*, X. Jiang n

Contributors: H. Wu n, H. Kim n, B. Zhang n, J. Kim*, P. Dayton*, Z. Xu*, X. Jiang n

author keywords: Intravascular transducer; dual-frequency thrombolysis; sonothrombolysis; ultrasound catheter
TL;DR: An intravascular ultrasound transducer with a composite structure is reported, which can operate with the dual-frequency condition for enhancing the cavitation effect of infused contrast agents and showed a 34% improvement in the lysis rate when theDual-frequency excitation was applied with the nanodroplets infusion. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 15, 2022

2021 article

Laser beam guided magnetic scanning catheter for sonothrombolysis with real-time clot detection

INTERNATIONAL ULTRASONICS SYMPOSIUM (IEEE IUS 2021).

By: B. Zhang n, H. Wu n & X. Jiang n

Contributors: B. Zhang n, H. Wu n & X. Jiang n

author keywords: ultrasound transducers; microbubbles; magnetic catheter; thrombolysis; sonothrombolysis
TL;DR: A novel magnetically driven scanning catheter device that integrates a stacked transducer, a tiny ring magnet, and fiber-optic laser sensors for clot spot tracking during the thrombolysis process is reported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 15, 2022

2021 journal article

Magneto-sonothrombolysis with combination of magnetic microbubbles and nanodroplets

ULTRASONICS, 116.

By: B. Zhang n, H. Wu n, L. Goel n, H. Kim n, C. Peng n, J. Kim n, P. Dayton n, Y. Gao*, X. Jiang n

Contributors: B. Zhang n, H. Wu n, L. Goel n, H. Kim n, C. Peng n, J. Kim n, P. Dayton n, Y. Gao*, X. Jiang n

author keywords: Magnetic microbubbles; Magnetic nanoparticles; Nanodroplets; Sonothrombolysis; Cavitation
TL;DR: It is demonstrated that tPA-mediated magneto-sonothrombolysis in combining NDs with MMBs could significantly enhance in vitro lysis of both unretracted clots and retracted clots in a flow model with 30 min treatment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 23, 2021

2021 article

Miniaturized Dual-Mode Intravascular Transducer for Sonothrombolysis

2021 IEEE 16TH NANOTECHNOLOGY MATERIALS AND DEVICES CONFERENCE (NMDC 2021).

By: B. Zhang n, H. Wu n & X. Jiang n

Contributors: B. Zhang n, H. Wu n & X. Jiang n

author keywords: laser ultrasound; carbon nanoparticles; ultrasound transducer; sonothrombolysis; catheter ultrasound
TL;DR: A miniaturized dual-mode ultrasound transducer with piezoelectric stacks and a laser ultrasoundTransducer is presented, which combines a low-frequency tone burst sonication and a high-frequency laser ultrasound pulse excitation to achieve intravascular sonothrombolysis with enhanced thrombectomy efficiency and safety. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 2, 2022

2021 journal article

Nanodroplet-mediated catheter-directed sonothrombolysis of retracted blood clots

MICROSYSTEMS & NANOENGINEERING, 7(1).

By: L. Goel n, H. Wu n, B. Zhang n, J. Kim n, P. Dayton n, Z. Xu*, X. Jiang n

Contributors: L. Goel n, H. Wu n, B. Zhang n, J. Kim n, P. Dayton n, Z. Xu*, X. Jiang n

TL;DR: For the first time, it is demonstrated that a sub-megahertz, forward-viewing intravascular (FVI) transducer can be used for ND-mediated sonothrombolysis, in vitro and combined nanodroplet with tPA-mediatedSonothromBolysis was able to significantly enhance retracted clot lysis in retracted blood clots. (via Semantic Scholar)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: February 15, 2021

2021 review

Recent Advances in Transducers for Intravascular Ultrasound (IVUS) Imaging

[Review of ]. SENSORS, 21(10).

By: C. Peng n, H. Wu n, S. Kim*, X. Dai* & X. Jiang n

author keywords: atherosclerosis; intravascular ultrasound (IVUS) imaging; ultrasound transducer; multifrequency ultrasound imaging; multimodality IVUS imaging
MeSH headings : Coronary Artery Disease / diagnostic imaging; Equipment Design; Humans; Transducers; Ultrasonography; Ultrasonography, Interventional
TL;DR: A comprehensive review of recent advances in ultrasound transducers for IVUS imaging is given and IVUS-based multimodality intravascular imaging of atherosclerotic plaque is discussed. (via Semantic Scholar)
Source: Web Of Science
Added: July 12, 2021

2021 journal article

SAFETY EVALUATION OF A FORWARD-VIEWING INTRAVASCULAR TRANSDUCER FOR SONOTHROMBOLYSIS: AN IN VITRO AND EX VIVO STUDY

ULTRASOUND IN MEDICINE AND BIOLOGY, 47(11), 3231–3239.

By: L. Goel n, H. Wu n, B. Zhang n, J. Kim n, P. Dayton n, Z. Xu*, X. Jiang n

Contributors: L. Goel n, H. Wu n, B. Zhang n, J. Kim n, P. Dayton n, Z. Xu*, X. Jiang n

author keywords: Intravascular sonothrombolysis; Safety; Retracted clots; Nanodroplets; Microbubbles; Ultrasound-assisted thrombolysis; Tissue plasminogen activator
MeSH headings : Animals; Microbubbles; Particle Size; Thrombolytic Therapy; Thrombosis / therapy; Tissue Plasminogen Activator; Transducers; Ultrasonic Therapy
TL;DR: In vitro and ex vivo tests using FVI transducers revealed a temperature rise of less than 1°C, no vessel damage as assessed by histology and no downstream clot particles >500 µm, which indicates that the F VI transducer poses minimal risk for sonothrombolysis applications and should be further evaluated in animal models. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 26, 2021

2021 article

Ultrasound Imaging-Guided Microbubble-Mediated Catheter-Directed Sonothrombolysis: An In-Vitro Study

2021 IEEE 16TH NANOTECHNOLOGY MATERIALS AND DEVICES CONFERENCE (NMDC 2021).

By: C. Peng n, B. Zhang n, H. Wu n, P. Dayton n, Z. Xu* & X. Jiang n

UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: May 2, 2022

2021 article

Ultrasound and Magnetic Dual-Mode Stacked Transducer for High-Frequency Magneto- Sonothrombolysis

2021 IEEE 16TH NANOTECHNOLOGY MATERIALS AND DEVICES CONFERENCE (NMDC 2021).

By: B. Zhang n, H. Wu n & X. Jiang n

Contributors: B. Zhang n, H. Wu n & X. Jiang n

author keywords: microbubbles; magnetic nanoparticle; ultrasound transducer; sonothrombolysis
TL;DR: The results showed that the combined effects of localized hyperthermia from the high-frequency oscillation of SPIONs and mechanical shock waves from ultrasound could effectively enhance the tPA-mediated sonothrombolysis efficacy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: May 2, 2022

2020 journal article

A 1.5-D Array for Acoustic Radiation Force (ARF)-Induced Peak Displacement-Based Tissue Anisotropy Assessment With a Row-Column Excitation Method

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 68(4), 1278–1287.

By: H. Wu n, M. Hossain n, H. Kim n, C. Gallippi n & X. Jiang n

author keywords: Transducers; Flexible printed circuits; Acoustics; Fabrication; Impedance; Anisotropic magnetoresistance; Muscles; 15-D array; acoustic radio forced impulse (ARFI); anisotropy; fractional anisotropy; peak displacement (PD); row-column excitation
MeSH headings : Acoustics; Anisotropy; Mechanical Phenomena; Phantoms, Imaging; Transducers
TL;DR: The results suggest that the array is capable of assessing DoA using PD ratio without physical rotation of the transducer and has the potential to reduce the misalignment errors for DoA assessment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 27, 2021

2020 journal article

EXAMINING THE INFLUENCE OF LOW-DOSE TISSUE PLASMINOGEN ACTIVATOR ON MICROBUBBLE-MEDIATED FORWARD-VIEWING INTRAVASCULAR SONOTHROMBOLYSIS

ULTRASOUND IN MEDICINE AND BIOLOGY, 46(7), 1698–1706.

By: L. Goel n, H. Wu n, H. Kim n, B. Zhang n, J. Kim n, P. Dayton n, Z. Xu*, X. Jiang n

Contributors: L. Goel n, H. Wu n, H. Kim n, B. Zhang n, J. Kim n, P. Dayton n, Z. Xu*, X. Jiang n

author keywords: Sonothrombolysis; Intravascular sonothrombolysis; Microbubble-mediated sonothrombolysis; Clot lysis; Tissue plasminogen activator
MeSH headings : Animals; Cattle; Combined Modality Therapy; Mechanical Thrombolysis / methods; Microbubbles / therapeutic use; Thrombolytic Therapy / methods; Thrombosis / drug therapy; Thrombosis / therapy; Tissue Plasminogen Activator / administration & dosage; Tissue Plasminogen Activator / therapeutic use; Ultrasonic Therapy / methods
TL;DR: Changes in stable and inertial cavitation doses were observed, corresponding to changes in clot lysis in MB-mediated FVI sonothrombolysis with and without tPA. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: July 20, 2020

2019 journal article

Sonothrombolysis with magnetic microbubbles under a rotational magnetic field

ULTRASONICS, 98, 62–71.

By: B. Zhang n, H. Kim n, H. Wu n, Y. Gao* & X. Jiang n

Contributors: B. Zhang n, H. Kim n, H. Wu n, Y. Gao* & X. Jiang n

author keywords: Magnetic microbubbles; Magnetic nanoparticle; Thrombolysis; Sonothrombolysis; Cavitation
TL;DR: A new method using the rotational magnetic field to trap and vibrate magnetic microbubbles at target clot region and then using an intravascular forward-looking ultrasound transducer to activate them acoustically significantly enhances in vitro lysis of blood clot. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: September 9, 2019

2017 article

MINIATURIZED FOCUSED ULTRASOUND TRANSDUCERS FOR INTRAVASCULAR THERAPIES

PROCEEDINGS OF THE ASME INTERNATIONAL MECHANICAL ENGINEERING CONGRESS AND EXPOSITION, 2017, VOL 3.

By: J. Kim n, H. Wu n & X. Jiang n

UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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