Hongliang Xin

Works (4)

Updated: July 5th, 2023 15:38

2017 article

Drug Delivery: Thrombin‐Responsive Transcutaneous Patch for Auto‐Anticoagulant Regulation (Adv. Mater. 4/2017)

Zhang, Y., Yu, J., Wang, J., Hanne, N. J., Cui, Z., Qian, C., … Gu, Z. (2017, January 1). Advanced Materials, Vol. 29.

By: Y. Zhang n, J. Yu n, J. Wang  n, N. Hanne  n, Z. Cui n, C. Qian  n, C. Wang n, H. Xin n ...

topics (OpenAlex): Neurological disorders and treatments
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: NC State University Libraries, NC State University Libraries
Added: August 6, 2018

2017 article

Relay Drug Delivery for Amplifying Targeting Signal and Enhancing Anticancer Efficacy

Hu, Q., Sun, W., Qian, C., Bomba, H. N., Xin, H., & Gu, Z. (2017, February 3). Advanced Materials.

By: Q. Hu n, W. Sun n, C. Qian n, H. Bomba n, H. Xin n & Z. Gu n

MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / pharmacokinetics; Biomimetic Materials / chemistry; Blood Vessels / drug effects; Blood Vessels / metabolism; Cell Line, Tumor; Cell Survival / drug effects; Cells, Cultured; Dextrans / chemistry; Drug Delivery Systems; Human Umbilical Vein Endothelial Cells / drug effects; Human Umbilical Vein Endothelial Cells / metabolism; Humans; Mice, Nude; Microtubules / enzymology; Microtubules / metabolism; Nanostructures / chemistry; Neoplasm Transplantation; Neoplasms / blood supply; Neoplasms / drug therapy; Neoplasms / metabolism; Oligopeptides / chemistry; Paclitaxel / administration & dosage; Paclitaxel / pharmacokinetics; Tumor Necrosis Factor-alpha / chemistry; Tumor Necrosis Factor-alpha / pharmacokinetics
topics (OpenAlex): RNA Interference and Gene Delivery; Advanced biosensing and bioanalysis techniques; Nanoplatforms for cancer theranostics
TL;DR: A "relay drug delivery" system based on two distinct modules that can specifically induce tumor blood vessel inflammation generation and an execution biomimetic nanocarrier B that can accumulate at the tumor site by receiving the broadcasting signals generated by NCA is developed for amplifying active tumor targeting signal and enhancing antitumor therapy. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 article

Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus

Hu, Q., Qian, C., Sun, W., Wang, J., Chen, Z., Bomba, H. N., … Gu, Z. (2016, September 14). Advanced Materials.

By: Q. Hu n, C. Qian n, W. Sun n, J. Wang n, Z. Chen n, H. Bomba n, H. Xin n, Q. Shen *, Z. Gu n

MeSH headings : Animals; Biomimetic Materials / chemistry; Biomimetic Materials / pharmacokinetics; Biomimetics; Blood Platelets / cytology; Bone and Bones / metabolism; Cell Line, Tumor; Cell Membrane / metabolism; Cellular Microenvironment; Disease Models, Animal; Drug Carriers / chemistry; Drug Carriers / pharmacokinetics; Humans; Mice; Multiple Myeloma / complications; Multiple Myeloma / drug therapy; Multiple Myeloma / metabolism; Multiple Myeloma / pathology; Nanoparticles / chemistry; Thrombosis / complications; Thrombosis / drug therapy
topics (OpenAlex): Multiple Myeloma Research and Treatments; Dendrimers and Hyperbranched Polymers; Protein Degradation and Inhibitors
TL;DR: A platelet-membrane-coated biomimetic nanocarrier, which can sequentially target the bone microenvironment and Myeloma cells to enhance the drug availability at the myeloma site and decrease off-target effects, is developed for inhibiting multiple myelomas growth and simultaneously eradicating thrombus complication. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 article

Synergistic Transcutaneous Immunotherapy Enhances Antitumor Immune Responses through Delivery of Checkpoint Inhibitors

Ye, Y., Wang, J., Hu, Q., Hochu, G. M., Xin, H., Wang, C., & Gu, Z. (2016, September 6). ACS Nano.

By: Y. Ye n, J. Wang n, Q. Hu  n, G. Hochu n, H. Xin n, C. Wang n, Z. Gu n

author keywords: drug delivery; immunotherapy; anti-PD1; IDO; microneedle
MeSH headings : Animals; Cell Cycle Checkpoints / drug effects; Drug Delivery Systems; Immunosuppression Therapy; Immunotherapy / methods; Indoleamine-Pyrrole 2,3,-Dioxygenase / therapeutic use; Melanoma / therapy; Programmed Cell Death 1 Receptor / therapeutic use; Skin Neoplasms / therapy; Tumor Microenvironment
topics (OpenAlex): Immunotherapy and Immune Responses; Advancements in Transdermal Drug Delivery; Cancer Immunotherapy and Biomarkers
TL;DR: This synergistic immunotherapy strategy locally targets the immunoinhibitory receptor programmed cell death protein 1 (PD1) and immunosuppressive enzyme indoleamine 2,3-dioxygenase (IDO) for the treatment of melanoma through a microneedle-based transcutaneous delivery approach and achieves potent antitumor efficacy. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2026) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.