Haiou Yang

Works (4)

Updated: August 23rd, 2023 21:14

2010 journal article

Binding site on human immunoglobulin G for the affinity ligand HWRGWV

Journal of Molecular Recognition, 23(3), 271–282.

By: H. Yang, P. Gurgel, D. Williams, B. Bobay, J. Cavanagh, D. Muddiman , R. Carbonell

Source: NC State University Libraries
Added: August 6, 2018

2008 article

Purification of human immunoglobulin G via Fc-specific small peptide ligand affinity chromatography

Yang, H., Gurgel, P. V., & Carbonell, R. G. (2008, December 9). Journal of Chromatography A.

By: H. Yang n, P. Gurgel n & R. Carbonell n

author keywords: Human immunoglobulin G; Fc fragment; Hexamer peptide ligand; Affinity chromatography; Ligand density
MeSH headings : Adsorption; Chromatography, Affinity / methods; Culture Media; Humans; Immobilized Proteins / chemistry; Immobilized Proteins / metabolism; Immunoglobulin Fc Fragments / metabolism; Immunoglobulin G / isolation & purification; Immunoglobulin G / metabolism; Kinetics; Ligands; Peptides / chemistry; Peptides / metabolism; Temperature
topics (OpenAlex): Monoclonal and Polyclonal Antibodies Research; Protein purification and stability; Glycosylation and Glycoproteins Research
TL;DR: The results indicate that these small peptide ligands, especially HWRGWV, offer a potential alternative to the use of Protein A or Protein G for large scale affinity chromatography. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

2005 article

Hexamer peptide affinity resins that bind the Fc region of human immunoglobulin G

Yang, H., Gurgel, P. V., & Carbonell, R. G. (2005, December 1). Journal of Peptide Research.

By: H. Yang n, P. Gurgel n & R. Carbonell n

author keywords: affinity chromatography; Fc fragment; hexapeptide; immunoglobulin
topics (OpenAlex): Monoclonal and Polyclonal Antibodies Research; Glycosylation and Glycoproteins Research; Biochemical and Structural Characterization
TL;DR: It was found that HWRGWV possessed the potential to purify HIgG from complete mammalian cell culture medium containing 10% fetal calf serum with purity comparable to commercially available resins, but using milder elution conditions. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

patent

Purification of immunoglobulins using affinity chromatography and peptide ligands

Carbonell, R. G., Yang, H., & Gurgel, P. V. Washington, DC: U.S. Patent and Trademark Office.

By: R. Carbonell, H. Yang & P. Gurgel

Source: NC State University Libraries
Added: August 6, 2018

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