Works (25)
Updated: July 7th, 2023 21:14
2022 journal article
Endocrine response and outcome in 14 cats with insulin resistance and acromegaly treated with stereotactic radiosurgery (17 Gy)
AMERICAN JOURNAL OF VETERINARY RESEARCH, 83(1), 64–71.
MeSH headings : Acromegaly / veterinary; Animals; Cat Diseases; Cats; Insulin Resistance; Radiosurgery / adverse effects; Radiosurgery / veterinary
TL;DR:
The SRS protocol was well tolerated and associated with survival times similar to those reported previously, emphasizing the need for careful ongoing diabetic monitoring of acromegalic cats after pituitary gland irradiation.
(via Semantic Scholar)
avmajournals.avma.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: February 7, 2022
2022 journal article
Stereotactic radiotherapy (10 Gy X 3) for canine nonlymphomatous intranasal tumors is associated with prolonged survival and minimal risk of severe radiotoxicity
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 260(12), 1496–1506.
MeSH headings : Dogs; Animals; Retrospective Studies; Dog Diseases / surgery; Quality of Life; Radiosurgery / methods; Radiosurgery / veterinary; Chondrosarcoma / veterinary; Bone Neoplasms / veterinary; Death; Treatment Outcome
TL;DR:
Oncologic outcomes following administration of a uniform stereotactic radiotherapy protocol for canine intranasal tumors are described and any clinical or dosimetric factors were predictive of event-free or overall survival time (EFST or OST) are identified.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: February 13, 2023
2021 journal article
Retrospective evaluation of intranasal carcinomas in cats treated with external-beam radiotherapy: 42 cases
JOURNAL OF VETERINARY INTERNAL MEDICINE, 35(2), 1018–1030.
author keywords: head and neck cancer; nasal cancer; nasal tumor; radiation therapy
MeSH headings : Animals; Carcinoma, Squamous Cell / veterinary; Cat Diseases / radiotherapy; Cats; Neoplasm Recurrence, Local / veterinary; Progression-Free Survival; Retrospective Studies; Treatment Outcome
TL;DR:
In cats with INC, DRT is associated with prolonged OST and PFS as compared to PRT, and if tumor progression occurs, a second course of DRT should be considered.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: March 22, 2021
2020 journal article
Cherenkov emissions for studying tumor changes during radiation therapy: An exploratory study in domesticated dogs with naturally-occurring cancer
PLOS ONE, 15(8).
MeSH headings : Animals; Dogs; Image Processing, Computer-Assisted; Neoplasms / diagnostic imaging; Neoplasms / radiotherapy; Particle Accelerators; Pilot Projects; Prospective Studies; Radiotherapy Dosage; Tomography, X-Ray Computed; X-Rays
TL;DR:
It is demonstrated that it is possible to obtain Cherenkov emissions from canine cancers within a fraction of radiotherapy, and lends credence to the goal of using this method during radiotherapy in human patients and client-owned pets.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: September 21, 2020
2019 journal article
Changes in target volume during irradiation of canine intranasal tumors can significantly impact radiation dosimetry
VETERINARY RADIOLOGY & ULTRASOUND, 60(5), 594–604.
author keywords: nasal tumor; normal tissue complications; radiation therapy
MeSH headings : Animals; Dog Diseases / pathology; Dog Diseases / radiotherapy; Dogs; Female; Imaging, Three-Dimensional / veterinary; Male; Nose Neoplasms / pathology; Nose Neoplasms / radiotherapy; Nose Neoplasms / veterinary; Radiometry / veterinary; Radiotherapy Planning, Computer-Assisted / veterinary; Radiotherapy, Conformal / veterinary; Radiotherapy, Intensity-Modulated / veterinary
TL;DR:
Results suggest that near-complete resolution of GTV warrants plan revision, and describe dosimetric effects of these changing volumes during a course of RT in veterinary medicine.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: July 15, 2019
2019 journal article
Radiobiological Characterization of Canine Malignant Melanoma Cell Lines with Different Types of Ionizing Radiation and Efficacy Evaluation with Cytotoxic Agents
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 20(4).
author keywords: canine malignant melanoma; ionizing radiation; photon; carbon ion; tumor hypoxia
MeSH headings : Animals; Cell Death / drug effects; Cell Death / radiation effects; Cell Line, Tumor; Cell Survival / drug effects; Cell Survival / radiation effects; Clone Cells; Cytotoxins / pharmacology; Cytotoxins / therapeutic use; Dogs; Melanoma / drug therapy; Melanoma / pathology; Melanoma / radiotherapy; Oxygen / metabolism; Radiation, Ionizing; Relative Biological Effectiveness; Survival Analysis; Treatment Outcome
TL;DR:
This study revealed that CMM has a wide range of radiosensitivity and that hypoxia can reduce it, indicating that widely used hypofractionated protocols may not be optimal for all CMM patients.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: April 2, 2019
2019 journal article
Stereotactic radiation therapy for canine multilobular osteochondrosarcoma: Eight cases
Veterinary and Comparative Oncology.
author keywords: axial skeleton tumour; multilobular osteochondroma; multilobular tumour of bone; radiosurgery; skull tumour
MeSH headings : Animals; Antineoplastic Agents / therapeutic use; Bone Neoplasms / drug therapy; Bone Neoplasms / radiotherapy; Bone Neoplasms / veterinary; Dog Diseases / drug therapy; Dog Diseases / radiotherapy; Dogs; Female; Male; North Carolina; Osteosarcoma / drug therapy; Osteosarcoma / radiotherapy; Osteosarcoma / veterinary; Retrospective Studies; Treatment Outcome
TL;DR:
This protocol was well-tolerated, but the duration of response was short-lived, and clinical signs associated with the MLO included a mass noted by owner, stertor, vestibular signs, exophthalmos and abnormal mentation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: September 8, 2019
2016 journal article
Retrospective evaluation of interfractional ureteral movement in dogs undergoing radiation therapy to elucidate appropriate setup margins
Veterinary Radiology & Ultrasound, 57(2), 170–179.
author keywords: organs at risk; planning target volume expansion; radiation therapy; ureter
MeSH headings : Animals; Dog Diseases / radiotherapy; Dogs; Patient Positioning / methods; Patient Positioning / veterinary; Radiotherapy, Image-Guided / veterinary; Reference Values; Retrospective Studies; Tomography, X-Ray Computed / veterinary; Ureter / diagnostic imaging; Urinary Bladder Neoplasms / radiotherapy; Urinary Bladder Neoplasms / veterinary
TL;DR:
This retrospective and descriptive study of 17 dogs with genitourinary carcinomas that underwent intensity-modulated, image-guided radiation therapy (IM-IGRT) was conducted to help radiation oncologists use appropriate ureter expansions for specific patient orientations and positioning verification methods.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, Web Of Science
Added: August 6, 2018
2015 journal article
Dosimetric consequences of using contrast-enhanced computed tomographic images for intensity-modulated stereotactic body radiotherapy planning
Veterinary Radiology & Ultrasound, 56(6), 687–695.
author keywords: dogs; intensity-modulated radiation therapy; stereotactic radiation therapy; translational research; veterinary
MeSH headings : Animals; Brain / radiation effects; Contrast Media; Cross-Sectional Studies; Dog Diseases / radiotherapy; Dogs; Extremities / radiation effects; Eye / radiation effects; Heart / radiation effects; Iohexol; Mouth Mucosa / radiation effects; Neoplasms / radiotherapy; Neoplasms / veterinary; Nose Neoplasms / radiotherapy; Nose Neoplasms / veterinary; Organs at Risk; Palate, Hard / radiation effects; Pelvic Neoplasms / radiotherapy; Pelvic Neoplasms / veterinary; Radiation Dosage; Radiographic Image Enhancement; Radiotherapy Dosage / veterinary; Radiotherapy Planning, Computer-Assisted / veterinary; Radiotherapy, Intensity-Modulated / veterinary; Retrospective Studies; Stereotaxic Techniques / veterinary; Tomography, X-Ray Computed / veterinary; Urinary Bladder / radiation effects
TL;DR:
Although caution would be recommended when planning IM-SBRT for tumors near "reservoirs" for contrast media (such as the heart and urinary bladder), findings supported the use of ceCT with this dose calculation algorithm for both target delineation and IM- SBRT treatment planning.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, Web Of Science
Added: August 6, 2018
2015 journal article
Pudendal Nerve and Internal Pudendal Artery Damage May Contribute to Radiation-Induced Erectile Dysfunction
International Journal of Radiation Oncology*Biology*Physics, 91(4), 796–806.
MeSH headings : Animals; Arteries / pathology; Arteries / radiation effects; Disease Models, Animal; Dogs; Erectile Dysfunction / drug therapy; Erectile Dysfunction / etiology; Impotence, Vasculogenic / drug therapy; Impotence, Vasculogenic / etiology; Male; Penis / blood supply; Penis / innervation; Penis / radiation effects; Prostate / blood supply; Prostate / innervation; Prostate / radiation effects; Pudendal Nerve / drug effects; Pudendal Nerve / pathology; Pudendal Nerve / physiopathology; Pudendal Nerve / radiation effects; Radiation Dosage; Radiosurgery / adverse effects; Radiosurgery / methods; Systole / physiology; Systole / radiation effects; Veins / pathology; Veins / radiation effects
TL;DR:
This is the first report in which prostatic irradiation was shown to cause morphologic arterial damage that was coincident with altered internal pudendal arterial tone, and in which decreased motor function in the pudendedal nerve was attributed to axonal degeneration and loss.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, Web Of Science
Added: August 6, 2018
2014 journal article
Predicting clinical outcome in feline oral squamous cell carcinoma: tumour initiating cells, telomeres and telomerase
Veterinary and Comparative Oncology, 14(4), 371–383.
author keywords: Bmi-1; cancer stem cells; CD44; feline oral squamous cell carcinoma; stereotactic radiation therapy; telomeres/telomerase
MeSH headings : Animals; Biomarkers, Tumor; Carcinoma, Squamous Cell / pathology; Carcinoma, Squamous Cell / veterinary; Cat Diseases / pathology; Cat Diseases / therapy; Cats; Female; Male; Mouth Neoplasms / pathology; Mouth Neoplasms / veterinary; Neoplastic Stem Cells / pathology; Predictive Value of Tests; Telomerase / metabolism; Telomere
TL;DR:
Results imply that Bmi-1 and telomerase may represent novel therapeutic targets in feline oral SCC, as their inhibition in combination with SRT - would be expected to have beneficial treatment outcome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: September 8, 2019
2013 journal article
A Translational Feline Model of Oral Squamous Cell Carcinoma for Evaluating Tumor Volume Delineation With PET/CT
Practical Radiation Oncology, 3(2), S29.
TL;DR:
The dose–response correlations as measured byFDG-PET difference potentially underlines the importance of FDG- PET as a measure of response, as well as the value of voxelized information.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: September 8, 2019
2013 journal article
Assessment of predictive molecular variables in feline oral squamous cell carcinoma treated with stereotactic radiation therapy
Veterinary and Comparative Oncology, 14(1), 39–57.
author keywords: feline oral squamous cell carcinoma; microvascular density; stereotactic radiation therapy
MeSH headings : Animals; Carcinoma, Squamous Cell / radiotherapy; Carcinoma, Squamous Cell / veterinary; Cat Diseases / radiotherapy; Cats; ErbB Receptors / genetics; ErbB Receptors / metabolism; Female; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Ki-67 Antigen / genetics; Ki-67 Antigen / metabolism; Male; Mouth Neoplasms / radiotherapy; Mouth Neoplasms / veterinary; Oxygen Consumption; Prognosis; Stereotaxic Techniques / veterinary; Survival Analysis
TL;DR:
MVD and degree of keratinization may be useful prognostic markers in cats with oral squamous cell carcinoma that underwent stereotactic radiation therapy (SRT) and SRT alone should be considered as a palliative treatment.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: September 8, 2019
2013 journal article
Comparison between 2-18f-fluoro-2-deoxy-d-glucose positron emission tomography and contrast-enhanced computed tomography for measuring gross tumor volume in cats with oral squamous cell carcinoma
Veterinary Radiology & Ultrasound, 54(3), 307–313.
author keywords: F-18-FDG PET; CT; feline oral squamous cell carcinoma; gross tumor volume; radiation therapy planning
MeSH headings : Animals; Carcinoma, Squamous Cell / diagnostic imaging; Carcinoma, Squamous Cell / pathology; Carcinoma, Squamous Cell / veterinary; Cat Diseases / diagnostic imaging; Cat Diseases / pathology; Cats; Female; Fluorodeoxyglucose F18; Male; Mouth Neoplasms / diagnostic imaging; Mouth Neoplasms / pathology; Mouth Neoplasms / veterinary; Positron-Emission Tomography / methods; Positron-Emission Tomography / veterinary; Prospective Studies; Radiopharmaceuticals; Tomography, X-Ray Computed / methods; Tomography, X-Ray Computed / veterinary; Tumor Burden
TL;DR:
It is indicated that (18) F-FDG PET warrants further investigation as a supplemental imaging modality in cats with oral squamous cell carcinoma because it detected regions of possible primary tumor that were not detected on CT images.
(via Semantic Scholar)
Source: Crossref
Added: January 21, 2021
2013 journal article
Evaluation of 18F-FDG PET/CT as a diagnostic imaging and staging tool for feline oral squamous cell carcinoma
Veterinary and Comparative Oncology, 14(1), 28–38.
author keywords: feline; fluorodeoxyglucose; oral; PET; CT; squamous cell carcinoma
MeSH headings : Animals; Carcinoma, Squamous Cell / diagnosis; Carcinoma, Squamous Cell / veterinary; Cat Diseases / diagnosis; Cat Diseases / pathology; Cats; Female; Fluorodeoxyglucose F18 / pharmacology; Lymph Nodes / pathology; Male; Mouth Neoplasms / diagnosis; Mouth Neoplasms / veterinary; Positron-Emission Tomography / veterinary; Tomography, X-Ray Computed / veterinary
TL;DR:
Tumors invading the osseous structures were more similar in extent on 18FDG-PET/CT and CT although they were more conspicuous on PET images, and three cytologically confirmed metastases were hypermetabolic on PET, while two of those metastase were equivocal on CT.
(via Semantic Scholar)
Source: Crossref
Added: September 8, 2019
2013 journal article
Evaluation of canine prostate intrafractional motion using serial cone beam computed tomography imaging
Veterinary Radiology & Ultrasound, 54(1), 93–98.
author keywords: canine; CBCT; intrafractional; prostate; radiation therapy; rectal balloon; SBRT; translational
MeSH headings : Animals; Cone-Beam Computed Tomography / methods; Cone-Beam Computed Tomography / veterinary; Dog Diseases / diagnostic imaging; Dog Diseases / surgery; Dogs; Humans; Immobilization; Male; Patient Positioning / veterinary; Prostate / diagnostic imaging; Prostatic Neoplasms / diagnostic imaging; Prostatic Neoplasms / surgery; Prostatic Neoplasms / veterinary; Radiosurgery / methods; Radiosurgery / veterinary; Radiotherapy Setup Errors / prevention & control; Radiotherapy, Image-Guided / instrumentation; Radiotherapy, Image-Guided / methods; Urethra / diagnostic imaging
TL;DR:
Minimal intrafraction variability using appropriate patient positioning and rectal balloon, combined with kV CBCT image-guided radiation therapy tools to account for interfraction changes, permit accurate and precise targeting of structures of interest.
(via Semantic Scholar)
Source: Crossref
Added: April 5, 2021
2012 journal article
Immunohistochemical characterization of feline oral squamous cell carcinoma
American Journal of Veterinary Research, 73(11), 1801–1806.
MeSH headings : Animals; Carcinoma, Squamous Cell / blood supply; Carcinoma, Squamous Cell / metabolism; Carcinoma, Squamous Cell / pathology; Carcinoma, Squamous Cell / veterinary; Cats; ErbB Receptors / genetics; ErbB Receptors / metabolism; Gene Expression Regulation, Neoplastic / physiology; Immunohistochemistry / veterinary; Ki-67 Antigen / genetics; Ki-67 Antigen / metabolism; Mouth Neoplasms / blood supply; Mouth Neoplasms / metabolism; Mouth Neoplasms / pathology; Neovascularization, Pathologic / veterinary; Retrospective Studies
TL;DR:
Results suggested that EGFR expression might be a valuable prognostic factor for treatment outcome in feline oral SCC and identified higher angiogenesis in tongue SCC, compared with mandibular and maxillary S CC, which may account for a different clinical outcome.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: September 11, 2019
2012 journal article
Repeatability of a planning target volume expansion protocol for radiation therapy of regional lymph nodes in canine and feline patients with head tumors
Veterinary Radiology & Ultrasound, 53(6), 667–672.
author keywords: head lymph nodes; PTV margin; radiation therapy; setup reproducibility dogs and cats
MeSH headings : Animals; Cat Diseases / radiotherapy; Cats; Dog Diseases / radiotherapy; Dogs; Head and Neck Neoplasms / radiotherapy; Head and Neck Neoplasms / veterinary; Lymphatic Irradiation / veterinary; Radiotherapy Planning, Computer-Assisted / veterinary
TL;DR:
When the patient immobilization devices and bony anatomy matching are used to align the primary head target and these LNs are treated simultaneously, an asymmetrical PTV expansion that ranges 4-9 mm (dogs) and 2-4 mm(cats), depending on the directions of couch movement, should be used to include the LNs within the PTV at least 95% of the time.
(via Semantic Scholar)
Source: Crossref
Added: April 5, 2021
2009 journal article
External beam radiation therapy for canine intracranial meningioma
The Canadian Veterinary Journal / La Revue Veterinaire Canadienne, 50(1), 97–100.
Source: NC State University Libraries
Added: April 24, 2021
2009 journal article
Impact of tissue inhomogeneity on dose distribution in the canine carpal and tarsal regions for cobalt and 6MV photons
Veterinary Radiology & Ultrasound, 50(3), 319–322.
author keywords: canine; distal extremity; dose distribution; radiation therapy; tissue inhomogeneity
MeSH headings : Animals; Ankle / radiation effects; Bone and Bones / radiation effects; Carpus, Animal / radiation effects; Cobalt; Dogs; Photons; Radiation Dosage; Radiotherapy, High-Energy / veterinary
TL;DR:
The PTV dose achieved without using inhomogeneity correction for cobalt photons results in potentially significant under dosing of portions of the PTV.
(via Semantic Scholar)
Source: Crossref
Added: January 24, 2021
2009 journal article
Use of a petroleum-based bolus for photon radiation therapy of distal extremities in dogs
Veterinary Radiology & Ultrasound, 50(2), 235–238.
author keywords: bolus; photon; radiation therapy
MeSH headings : Animals; Bone Neoplasms / radiotherapy; Bone Neoplasms / veterinary; Dog Diseases / radiotherapy; Dogs; Dose-Response Relationship, Radiation; Extremities / radiation effects; Petroleum; Photons / therapeutic use; Radiotherapy Dosage; Radiotherapy Planning, Computer-Assisted; Radiotherapy, Conformal / instrumentation; Radiotherapy, Conformal / methods; Radiotherapy, Conformal / veterinary; Radiotherapy, High-Energy / instrumentation; Radiotherapy, High-Energy / methods; Radiotherapy, High-Energy / veterinary; Tarsus, Animal / radiation effects; Technology, Radiologic
TL;DR:
This study assesses the dose homogeneity achieved using a petroleum-based bolus material, in combination with a commercially available sheet bolus, for radiation treatment of the canine tarsus, which is considered clinically acceptable by the authors.
(via Semantic Scholar)
Source: Crossref
Added: January 21, 2021
2008 journal article
A Dog with Osteosarcoma which Metastasized to the Eye Months before Metastasis to Other Organs
Journal of Veterinary Medical Science, 70(8), 825–828.
author keywords: canine; metastasis to the eye; osteosarcoma
MeSH headings : Animals; Antineoplastic Agents / therapeutic use; Combined Modality Therapy; Dog Diseases / pathology; Dogs; Eye Enucleation / veterinary; Eye Neoplasms / drug therapy; Eye Neoplasms / pathology; Eye Neoplasms / secondary; Eye Neoplasms / surgery; Eye Neoplasms / veterinary; Fatal Outcome; Male; Neoplasm Metastasis / pathology; Osteosarcoma / drug therapy; Osteosarcoma / pathology; Osteosarcoma / surgery; Osteosarcoma / veterinary
TL;DR:
A 9-year-old male Shih Tzu with osteosarcoma had a forelimb amputation and underwent chemotherapy, and the right eye was enucleated due to refractory glaucoma, and was diagnosed as anterior uveal malignant melanoma.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: September 11, 2019
2008 journal article
A dog with squamous cell carcinoma in the middle ear
The Canadian Veterinary Journal / La Revue Veterinaire Canadienne, 49(9), 877–879.
Source: NC State University Libraries
Added: April 24, 2021
2008 journal article
Complications associated with the use of vascular access ports in dogs receiving external beam radiation therapy
Journal of the American Veterinary Medical Association, 233(1), 96–103.
MeSH headings : Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / therapeutic use; Catheters, Indwelling / adverse effects; Catheters, Indwelling / veterinary; Cohort Studies; Dog Diseases / drug therapy; Dogs; Female; Male; Neoplasms / drug therapy; Postoperative Complications / veterinary; Veterinary Medicine / instrumentation; Veterinary Medicine / methods
TL;DR:
Most complications were minor and self-limiting; however, a low risk of serious complications existed, and placement of VAPs provided ready access in dogs receiving radiation therapy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: September 11, 2019
2008 journal article
Odontoclastic Resorptive Lesions in a Dog
Journal of Veterinary Medical Science, 70(1), 103–105.
author keywords: canine; neck lesion; odontoclastic resorptive lesions
MeSH headings : Animals; Dog Diseases / pathology; Dogs; Male; Osteoclasts / pathology; Tooth / pathology; Tooth Resorption / pathology; Tooth Resorption / veterinary
TL;DR:
Since this is the first report of a dog with the same lesion in other teeth after the first treatment, it is hoped that better treatment and prevention methods are established.
(via Semantic Scholar)
Source: Crossref
Added: September 11, 2019
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