Ian Huntress

Dept Molecular Biomedical Scie

Works (5)

Updated: August 30th, 2025 05:04

2025 article

Cervicovaginal microbial features predict Chlamydia trachomatis spread to the upper genital tract of infected women

Jeong, S., Tollison, T., Brochu, H., Chou, H., Huntress, I., Yount, K. S., … Peng, X. (2025, August 12). (M. Raffatellu, Ed.). Infection and Immunity, Vol. 8.

By: S. Jeong n, T. Tollison n, H. Brochu n , H. Chou n, I. Huntress n, K. Yount*, X. Zheng *, T. Darville *, C. O'Connell *, X. Peng n 

Ed(s): M. Raffatellu

author keywords: cervicovaginal microbiome; <italic>Chlamydia trachomatis</italic>; upper genital tract infection; 16S rRNA sequencing
topics (OpenAlex): Reproductive tract infections research; Pelvic floor disorders treatments; Urinary Tract Infections Management
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3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 12, 2025

2025 article

Human long noncoding RNA VILMIR is induced by major respiratory viral infections and modulates the host interferon response

John, K., Huntress, I., Smith, E., Chou, H., Tollison, T. S., Covarrubias, S., … Peng, X. (2025, March 25). (T. Gallagher, Ed.). Journal of Virology, Vol. 3.

By: K. John n, I. Huntress n, E. Smith n, H. Chou  n, T. Tollison n, S. Covarrubias *, E. Crisci n , S. Carpenter *, X. Peng n 

Ed(s): T. Gallagher

author keywords: interferon; lncRNA; influenza; SARS-CoV-2; RSV; ISG; RNA-seq
MeSH headings : Humans; RNA, Long Noncoding / genetics; RNA, Long Noncoding / metabolism; A549 Cells; Interferon-beta / pharmacology; SARS-CoV-2 / immunology; COVID-19 / genetics; COVID-19 / immunology; COVID-19 / virology; Influenza, Human / genetics; Influenza, Human / immunology; Influenza, Human / virology; Influenza A virus / immunology; Respiratory Syncytial Virus Infections / genetics; Respiratory Syncytial Virus Infections / immunology; Respiratory Syncytial Virus Infections / virology; Epithelial Cells / virology; Interferons; Host-Pathogen Interactions; Cell Line
topics (OpenAlex): Cancer-related molecular mechanisms research; RNA modifications and cancer; interferon and immune responses
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3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: March 25, 2025

2025 journal article

Injection of vocal fold lamina propria-derived hydrogels modulates fibrosis in injured vocal folds

Biomaterials Advances, 178, 214424.

By: C. Mora-Navarro  n, E. Smith n, Z. Wang n , M. Ramos-Alamo*, L. Collins n , N. Awad*, D. Cruz *, T. Tollison n ...

author keywords: Vocal fold lamina propria; Fibrosis; Extracellular matrix; Hydrogels; TGF-(31
topics (OpenAlex): Voice and Speech Disorders; Dysphagia Assessment and Management; Tissue Engineering and Regenerative Medicine
Sources: Web Of Science, NC State University Libraries, Crossref
Added: August 25, 2025

2021 article

Coupling high-throughput mapping with proteomics analysis delineates cis-regulatory elements at high resolution

Wu, T., Jiang, D., Zou, M., Sun, W., Wu, D., Cui, J., … Li, G. (2021, September 17). Nucleic Acids Research, Vol. 50.

By: T. Wu *, D. Jiang *, M. Zou *, W. Sun *, D. Wu, J. Cui *, I. Huntress n, X. Peng n , G. Li *

MeSH headings : Chromosome Mapping / methods; Gene Expression Regulation; Genome, Human; High-Throughput Nucleotide Sequencing / methods; Humans; Regulatory Sequences, Nucleic Acid
topics (OpenAlex): Genomics and Chromatin Dynamics; Epigenetics and DNA Methylation; RNA Research and Splicing
TL;DR: The utility of Reel-seq and FREP-MS analyses for the systematic identification of cis-REs at high resolution over a large region of the human genome in a systematic and continuous manner is confirmed. (via Semantic Scholar)
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Sources: Web Of Science, NC State University Libraries
Added: February 14, 2022

2021 article

Tumor Necrosis Factor Alpha-Induced Interleukin-1 Alpha Synthesis and Cell Death Is Increased in Mouse Epithelial Cells Infected With Chlamydia muridarum

Nagarajan, U. M., Cho, C., Gyorke, C. E., Nagarajan, S., Ezzell, J. A., Brochu, H., … Peng, X. (2021, March 25). The Journal of Infectious Diseases, Vol. 224, pp. S47–S55.

By: U. Nagarajan *, C. Cho *, C. Gyorke*, S. Nagarajan*, J. Ezzell *, H. Brochu n , I. Huntress n, E. Harrell n, X. Peng n 

author keywords: Chlamydia muridarum; IL-1 alpha; mouse epithelial cells; mouse model; TNF alpha
MeSH headings : Animals; Cell Death; Chlamydia Infections / immunology; Chlamydia Infections / metabolism; Chlamydia muridarum / immunology; Epithelial Cells; Female; Interleukin-1alpha / immunology; Interleukin-1alpha / metabolism; Mice; Mice, Inbred C57BL; Tumor Necrosis Factor-alpha / immunology; Tumor Necrosis Factor-alpha / metabolism
topics (OpenAlex): Reproductive tract infections research; Immune Response and Inflammation; Reproductive Physiology in Livestock
TL;DR: The results suggest TNFα and IL-1α enhance each other's downstream effects resulting in a hyperinflammatory response to chlamydial infection and propose that biologics targeting TNF-induced IL- 1α synthesis could be used to mitigate tissue damage during chlamYDial infection. (via Semantic Scholar)
UN Sustainable Development Goals Color Wheel
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: September 13, 2021

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