Irina Koryakina
Works (6)
Updated: July 5th, 2023 15:46
2017 journal article
Polyketide Bioderivatization Using the Promiscuous Acyltransferase KirCII
ACS Synthetic Biology, 6(3), 421–427.
co-author countries:
Germany 🇩🇪 Denmark 🇩🇰 United States of America 🇺🇸
author keywords: antibiotic; kirromycin; polyketide synthase; trans-acyltransferase; engineering click chemistry
MeSH headings : Acyltransferases / metabolism; Anti-Bacterial Agents / metabolism; Bacteria / metabolism; Bacterial Proteins / metabolism; Polyketide Synthases / metabolism; Polyketides / metabolism; Pyridones / metabolism
europepmc.org (repository)
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2014 journal article
Evaluating nonpolar surface area and liquid chromatography/mass spectrometry response: an application for site occupancy measurements for enzyme intermediates in polyketide biosynthesis
Rapid Communications in Mass Spectrometry, 28(23), 2511–2522.
co-author countries:
United States of America 🇺🇸
MeSH headings : Acyltransferases / metabolism; Chromatography, Liquid / methods; Filtration; Hydrophobic and Hydrophilic Interactions; Mass Spectrometry / methods; Oligopeptides / chemistry; Oligopeptides / metabolism; Peptide Fragments / chemistry; Peptide Fragments / metabolism; Polyketides / chemistry; Polyketides / metabolism
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2013 journal article
Promiscuity of a modular polyketide synthase towards natural and non-natural extender units
Organic & Biomolecular Chemistry, 11(27), 4449.
co-author countries:
United States of America 🇺🇸
MeSH headings : Acyl Coenzyme A / chemistry; Acyl Coenzyme A / metabolism; Bacterial Proteins / chemistry; Bacterial Proteins / metabolism; Coenzyme A Ligases / chemistry; Coenzyme A Ligases / metabolism; Polyketide Synthases / chemistry; Polyketide Synthases / metabolism; Protein Structure, Tertiary; Rhizobium / chemistry; Rhizobium / enzymology; Rhizobium / metabolism; Substrate Specificity
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2012 journal article
Poly Specific trans-Acyltransferase Machinery Revealed via Engineered Acyl-CoA Synthetases
ACS Chemical Biology, 8(1), 200–208.
co-author countries:
Germany 🇩🇪
MeSH headings : Acyltransferases / chemistry; Acyltransferases / genetics; Bacterial Proteins / chemistry; Bacterial Proteins / genetics; Chromatography, Liquid; Coenzyme A Ligases / chemistry; Coenzyme A Ligases / genetics; Crystallography, X-Ray; Genetic Variation; Models, Molecular; Substrate Specificity
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2011 journal article
A High-Throughput Screen for Directed Evolution of the Natural Product Sulfotransferase LipB
Journal of Biomolecular Screening, 16(8), 845–851.
co-author countries:
United States of America 🇺🇸
author keywords: chemistry; medicinal; organic; synthetic; and combinatorial; enzyme assays or enzyme kinetics; anti-infective drugs; natural products screening
MeSH headings : Acyltransferases / chemistry; Acyltransferases / genetics; Acyltransferases / metabolism; Aminoglycosides / metabolism; Biocatalysis; Biological Products / chemistry; Biological Products / metabolism; Biotransformation; Cloning, Molecular; Colorimetry; Escherichia coli / chemistry; Escherichia coli / enzymology; Escherichia coli / genetics; Escherichia coli Proteins / chemistry; Escherichia coli Proteins / genetics; Escherichia coli Proteins / metabolism; Gene Library; High-Throughput Screening Assays; Nitrobenzenes / analysis; Nitrobenzenes / metabolism; Plasmids; Recombinant Proteins / chemistry; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Small Molecule Libraries / analysis; Small Molecule Libraries / chemistry; Substrate Specificity
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
2011 journal article
Mutant Malonyl-CoA Synthetases with Altered Specificity for Polyketide Synthase Extender Unit Generation
ChemBioChem, 12(15), 2289–2293.
co-author countries:
United States of America 🇺🇸
author keywords: directed evolution; enzymes; polyketides; protein engineering; specificity
MeSH headings : Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Cloning, Molecular; Coenzyme A Ligases / genetics; Coenzyme A Ligases / metabolism; Mutagenesis; Mutant Proteins / genetics; Mutant Proteins / metabolism; Polyketide Synthases / metabolism; Rhizobium / enzymology; Rhizobium / genetics; Substrate Specificity
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018
