Works (6)

2017 journal article

Polyketide Bioderivatization Using the Promiscuous Acyltransferase KirCII

ACS Synthetic Biology, 6(3), 421–427.

By: E. Musiol-Kroll*, F. Zubeil*, T. Schafhauser*, T. Härtner*, A. Kulik*, J. McArthur, I. Koryakina, W. Wohlleben* ...

author keywords: antibiotic; kirromycin; polyketide synthase; trans-acyltransferase; engineering click chemistry
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2014 journal article

Evaluating nonpolar surface area and liquid chromatography/mass spectrometry response: an application for site occupancy measurements for enzyme intermediates in polyketide biosynthesis

Rapid Communications in Mass Spectrometry, 28(23), 2511–2522.

By: S. Randall, I. Koryakina, G. Williams & D. Muddiman

Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2013 journal article

Promiscuity of a modular polyketide synthase towards natural and non-natural extender units

Organic & Biomolecular Chemistry, 11(27), 4449.

By: I. Koryakina, J. McArthur, M. Draelos & G. Williams

Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2012 journal article

Poly Specific trans-Acyltransferase Machinery Revealed via Engineered Acyl-CoA Synthetases

ACS Chemical Biology, 8(1), 200–208.

By: I. Koryakina, J. McArthur, S. Randall, M. Draelos, E. Musiol*, D. Muddiman, T. Weber*, G. Williams

Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2011 journal article

A High-Throughput Screen for Directed Evolution of the Natural Product Sulfotransferase LipB

Journal of Biomolecular Screening, 16(8), 845–851.

By: I. Koryakina, J. Neville n, K. Nonaka*, S. Van Lanen* & G. Williams

author keywords: chemistry; medicinal; organic; synthetic; and combinatorial; enzyme assays or enzyme kinetics; anti-infective drugs; natural products screening
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018

2011 journal article

Mutant Malonyl-CoA Synthetases with Altered Specificity for Polyketide Synthase Extender Unit Generation

ChemBioChem, 12(15), 2289–2293.

By: I. Koryakina & G. Williams

author keywords: directed evolution; enzymes; polyketides; protein engineering; specificity
Sources: Web Of Science, ORCID, Crossref
Added: August 6, 2018