Works (6)

Updated: December 19th, 2023 05:03

2023 journal article

Delivering Robust Proton-Only Sensing of Hyperpolarized [1,2-<SUP>13</SUP>C<sub>2</sub>]-Pyruvate Using Broad-Spectral-Range Nuclear Magnetic Resonance Pulse Sequences

ACS SENSORS, 8(11), 4101–4110.

author keywords: parahydrogen; hyperpolarization; pyruvate; SABRE; protonsensing; molecular imaging
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 11, 2023

2023 journal article

Spin dynamics of [1,2-C-13(2)]pyruvate hyperpolarization by parahydrogen in reversible exchange at micro Tesla fields

PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 25(24), 16446–16458.

Contributors: A. Browning n, K. Macculloch n, P. TomHon n, I. Mandzhieva n, E. Chekmenev*, B. Goodson*, S. Lehmkuhl n, T. Theis n

UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: June 13, 2023

2022 article

Interplay of Near-Zero-Field Dephasing, Rephasing, and Relaxation Dynamics and [1-C-13]Pyruvate Polarization Transfer Efficiency in Pulsed SABRE-SHEATH

Nantogma, S., Eriksson, S. L., Adelabu, I., Mandzhieva, I., Browning, A., TomHon, P., … Chekmenev, E. Y. (2022, November 28). JOURNAL OF PHYSICAL CHEMISTRY A, Vol. 11.

MeSH headings : Pyruvic Acid
TL;DR: The application of microtesla pulses is studied to investigate their effect on C-13 polarization efficiency, compared to that of conventional SABRE-SHEATH employing a static field, to provide the matching conditions of polarization transfer from parahydrogen-derived hydrides to the 13C-1 nucleus. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 29, 2022

2022 article

Proton-Only Sensing of Hyperpolarized [1,2-C-13(2)]Pyruvate

Mandzhieva, I., Adelabu, I., Chekmenev, E. Y., & Theis, T. (2022, November 22). ACS SENSORS, Vol. 11.

By: I. Mandzhieva n, I. Adelabu*, E. Chekmenev* & T. Theis n

Contributors: I. Mandzhieva n, I. Adelabu*, E. Chekmenev* & T. Theis n

author keywords: Parahydrogen; hyperpolarization; pyruvate; SABRE; proton sensing; molecular imaging
MeSH headings : Protons; Magnetic Resonance Spectroscopy / methods; Pyruvic Acid / metabolism; Magnetic Resonance Imaging / methods; Contrast Media
TL;DR: The objective of this work is the development of an approach that works on conventional (i.e., proton-only) MRI systems while taking advantage of long-lived 13C hyperpolarization, which obviates 13C excitation and detection for proton sensing of 13C-hyperpolarized pyruvate. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 23, 2022

2022 article

Triplet Photosensitized para-Hydrogen Induced Polarization

Brown, E. E., Mandzhieva, I., TomHon, P. M., Theis, T., & Castellano, F. N. (2022, November 14). ACS CENTRAL SCIENCE, Vol. 11.

By: E. Brown n, I. Mandzhieva n, P. TomHon n, T. Theis n & F. Castellano n

Contributors: E. Brown n, I. Mandzhieva n, P. Tomhon n, T. Theis n & F. Castellano n

Sources: Web Of Science, ORCID, NC State University Libraries
Added: November 15, 2022

2021 article

Order-Unity C-13 Nuclear Polarization of [1-C-13]Pyruvate in Seconds and the Interplay of Water and SABRE Enhancement

Adelabu, I., TomHon, P., Kabir, M. S. H., Nantogma, S., Abdulmojeed, M., Mandzhieva, I., … Chekmenev, E. Y. (2021, December 9). CHEMPHYSCHEM, Vol. 11.

By: I. Adelabu*, P. TomHon n, M. Kabir*, S. Nantogma*, M. Abdulmojeed n, I. Mandzhieva n, J. Ettedgui*, R. Swenson* ...

Contributors: I. Adelabu*, P. TomHon n, M. Kabir*, S. Nantogma*, M. Abdulmojeed n, I. Mandzhieva n, J. Ettedgui*, R. Swenson* ...

author keywords: hyperpolarization; NMR spectroscopy; parahydrogen; C-13; pyruvate
MeSH headings : Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Nitrogen Isotopes; Pyruvic Acid; Water / chemistry
TL;DR: Signal Amplification By Reversible Exchange in SHield Enabled Alignment Transfer (SABRE-SHEATH) is investigated to achieve rapid hyperpolarization of 13C1 spins of [1-13C]pyruvate, using parahydrogen as the source of nuclear spin order. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: December 10, 2021

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